• PMID: 83595
• Gene Name: B2M
• Condition: Azoospermia
• Association: A higher level of beta-2m was found inazoospermia compared with that of normal sperms.
• Sex: Male
• Infertility type: Male infertility
• Other associated phenotypes: Azoospermia

[beta2-Microglobulin in human seminal fluid (author's transl)]

Sire J, Collé A, Pinatel MC, Fellous M, Manuel Y.

The expression of human beta2-microglobulin (beta2m) on human spermatozoa cell surface was investigated by cytotoxicity and immunofluorescence tests. beta2m was also found in human seminal fluid by use of immunochemical techniques. Seminal fluids obtained from couples with infertility problems were tested for beta2m, albumin and total proteins concentration. A higher level of beta-2m was found in azoospermia compared with that of normal sperms. FAU - Sire, J AU - Sire J FAU - Collé, A AU - Collé A FAU - Pinatel, M C AU - Pinatel MC FAU - Fellous, M AU - Fellous M