|
|
| GO term name | GO category | Gene symbols |
|---|
| 'de novo' AMP biosynthetic process | biological process | ADSS2, ADSS1, ADSL |
| 'de novo' cotranslational protein folding | biological process | HSPA14, DNAJC2 |
| 'de novo' CTP biosynthetic process | biological process | CTPS1, CTPS2 |
| 'de novo' GDP-L-fucose biosynthetic process | biological process | GMDS, TSTA3 |
| 'de novo' IMP biosynthetic process | biological process | GART, ATIC, PAICS, ADSL, PPAT, PFAS |
| 'de novo' NAD biosynthetic process from tryptophan | biological process | HAAO, KYNU, IDO2, IDO1, AFMID |
| 'de novo' posttranslational protein folding | biological process | SELENOF, ENTPD5, UGGT1 |
| 'de novo' protein folding | biological process | HSPD1, FKBP1B |
| 'de novo' pyrimidine nucleobase biosynthetic process | biological process | MTOR, CPS1, CMPK1, DHODH, UMPS, CAD |
| 'de novo' UMP biosynthetic process | biological process | DHODH, UMPS, CAD |
| 1-aminocyclopropane-1-carboxylate biosynthetic process | biological process | ACCS |
| 10-formyltetrahydrofolate biosynthetic process | biological process | MTHFD1, MTHFD1L |
| 10-formyltetrahydrofolate catabolic process | biological process | ALDH1L1, ALDH1L2 |
| 10-formyltetrahydrofolate metabolic process | biological process | MTHFD2L |
| 2-oxobutyrate biosynthetic process | biological process | THNSL2 |
| 2-oxobutyrate catabolic process | biological process | PHYH |
| 2-oxoglutarate metabolic process | biological process | IDH1, OGDH, D2HGDH, PHYH, GOT1, GPT2, IDH2, L2HGDH, TAT, AADAT, ADHFE1, GOT2, DLST |
| 3'-phospho-5'-adenylyl sulfate transmembrane transport | biological process | SLC35B3 |
| 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process | biological process | SLC35B3, SLC26A2, PAPSS2, SLC26A1 |
| 3'-phosphoadenosine 5'-phosphosulfate metabolic process | biological process | SULT1E1, SULT1A1, SULT2A1, TPST1, SULT4A1, SULT2B1, BPNT2, SULT1C2, ENPP1, SULT1B1, SULT1C4, SULT1A3, SULT1A4, SULT1A2 |
| 3'-UTR-mediated mRNA destabilization | biological process | ZC3H12A, DHX36, HNRNPD, UPF1, ZFP36L2, RC3H1, CPEB3, ZFP36, ZFP36L1, TRIM71, RBM24, MOV10, ZC3H12D, KHSRP, PLEKHN1 |
| 3'-UTR-mediated mRNA stabilization | biological process | MAPK14, HNRNPA0, YBX3, HNRNPC, RBM10, MYD88, ANGEL2, TIRAP, ELAVL4, ZFP36, RBM24, RBM38 |
| 4-hydroxyproline catabolic process | biological process | ALDH4A1, GOT2, HOGA1 |
| 4-hydroxyproline metabolic process | biological process | PRDX4 |
| 4-nitrophenol metabolic process | biological process | CYP2E1 |
| 5-methylcytosine catabolic process | biological process | TET3, TET1, TET2 |
| 5-phosphoribose 1-diphosphate biosynthetic process | biological process | PRPS2, PRPS1L1, PRPS1, PRPSAP1, PYGL, PRPSAP2 |
| 5S class rRNA transcription by RNA polymerase III | biological process | GTF3C6, GTF3C3, GTF3C1, GTF3C2, GTF3C5, GTF3C4 |
| 7,8-dihydroneopterin 3'-triphosphate biosynthetic process | biological process | GCH1 |
| 7-methylguanosine cap hypermethylation | biological process | TGS1 |
| 7-methylguanosine mRNA capping | biological process | ERCC2, GTF2H3, RNGTT, NCBP2, POLR2F, CDK7, CCNH, POLR2G, GTF2F1, NCBP1, POLR2B, SUPT5H, POLR2D, RNMT, CMTR2, POLR2J, POLR2L, POLR2E, GTF2H1, POLR2K, POLR2I, NCBP3, RAMAC, GTF2F2, GTF2H4, POLR2C, MNAT1, CMTR1, POLR2H, POLR2A, GTF2H5 |
| 7-methylguanosine RNA capping | biological process | TGS1 |
| 9-cis-retinoic acid biosynthetic process | biological process | CYP1A1, ALDH1A2, DHRS9, ALDH8A1 |
| 90S preribosome assembly | biological process | RPL38 |
| abortive mitotic cell cycle | biological process | PTPN11, PTPN6 |
| abscission | biological process | IST1, SPART, CHMP4C, AURKB |
| absorption of visible light | biological process | RHO |
| acetaldehyde metabolic process | biological process | RELA |
| acetate biosynthetic process | biological process | ACSS1, ACSS2 |
| acetate ester transport | biological process | SLC18A3, SLC22A1 |
| acetoacetic acid metabolic process | biological process | TYRP1 |
| acetyl-CoA biosynthetic process | biological process | MLYCD, ACLY, ACSS1, PPCS, ACSS2 |
| acetyl-CoA biosynthetic process from acetate | biological process | ACSS1, ACSS2 |
| acetyl-CoA biosynthetic process from pyruvate | biological process | PDHA1, PDHB, DLAT |
| acetyl-CoA metabolic process | biological process | HMGCS2, HMGCS1, FASN, ACACA, ACACB |
| acetyl-CoA transport | biological process | SLC33A1 |
| acetylcholine biosynthetic process | biological process | SLC44A4, SLC5A7, CHAT |
| acetylcholine receptor signaling pathway | biological process | LY6G6D, CHRM3, CHRNA7, CHRNA3, CHRNB2, CHRNA4, LY6H, CRKL |
| acetylcholine secretion | biological process | SLC44A4 |
| acid secretion | biological process | SLC22A16, DRD3, DRD2 |
| acinar cell differentiation | biological process | PROX1 |
| acrosomal vesicle exocytosis | biological process | RIMS1, EQTN, UNC13B, SYT6 |
| acrosome assembly | biological process | TXNDC8, SPACA1, AGFG1, TBPL1, MFSD14A, TBC1D20, PLA2G3, ACRBP, ZPBP2, CCDC136 |
| acrosome matrix dispersal | biological process | ACR |
| acrosome reaction | biological process | TNP2, ACR, IFTAP, PKDREJ, ABHD2, PCSK4, ROPN1B, GLRA1, SYT6, PLCD4 |
| actin cortical patch assembly | biological process | WIPF3 |
| actin cortical patch localization | biological process | WIPF3, WIPF1, TIGD5, WIPF2, WAS, BIN3 |
| actin crosslink formation | biological process | BAIAP2L1, BAIAP2, DPYSL3, EPS8, GAS2L1, ACTN1, GAS2L3, GAS2L2, MARCKS, GAS2, BAIAP2L2, AIF1 |
| actin cytoskeleton organization | biological process | NPHP1, CDC42, NPHP4, NF2, WASL, DYNLL1, SHROOM3, ARPC1A, CORO1B, MYH10, EHBP1, PALLD, FOXJ1, ARHGEF10, DIAPH2, TNXB, CSRP2, WASF3, BCL6, MOB2, RHOU, RFLNB, SPTBN5, ARHGEF11, VASP, TBCK, CORO1C, SLC9A3R1, ARPC5, WDR1, FLNB, KRAS, CAPZA1, SPECC1L, DLC1, ROCK2, BCR, PFN2, ABR, PDLIM1, ARHGEF5, PDLIM2, PLEK2, TAOK2, RND3, RHOG, AMOT, MRTFA, INF2, MTSS1, DIAPH1, ROCK1, IQSEC1, POF1B, PHACTR1, PACSIN2, CDC42EP2, ADRA2A, ATXN3, MICAL3, KLHL1, AMOTL2, STARD13, PDGFA, SSH2, EPB41L5, RHOQ, FGD6, IQSEC3, SDCBP, TYROBP, RHOBTB3, CSRP3, RAC1, SPIRE1, INPP5K, ARHGEF10L, SDAD1, WASF2, XIRP2, ABL1, RAC2, ADD2, CAPZA2, PRKG1, FMNL2, ARHGAP26, CSRP1, GAS2L3, SSH3, AGAP2, CXCL1, CAPZB, ACTR2, MICALCL, WASF1, PDLIM5, TMOD3, LDB3, SMTN, FLII, TRIP10, FGD4, PDLIM7, OPHN1, ARHGEF17, CYTH2, EHD2, CDC42BPB, SRF, ADD1, RAC3, FGD2, DAAM2, SSH1, NISCH, PDLIM4, DMTN, PDLIM3, RHOJ, CORO2B, MICAL2, ITPKA, CORO1A, CRK, PHACTR4, RHOV, NUAK2, PHACTR3, TESK2, FSCN2, PDPK1, PIP5K1C, LIMK1, PFN3, SHROOM2, SMTNL2, KLHL17, ARHGEF18, FSCN1, ABLIM2, |
| actin cytoskeleton reorganization | biological process | BRSK2, KIT, EZR, S100A9, ANTXR1, SHC1, PTK7, AUTS2, RALA, ANXA1, PLEK, CTTN, PLEK2, S1PR1, ATP2C1, PIP5K1A, DTNBP1, PHACTR1, THSD7A, EPS8, GRB2, GAB1, TNIK, FER, CXADR, PARVG, S1PR2, PARVB, PTPN1, PARVA, CDC42BPB, FARP2, FGF7, RAP2A, PDLIM4, MYH9, NRP1, CAPN10, INSRR, CDC42BPG, MICALL2, MINK1, THSD7B, GPR65, FGF10 |
| actin filament branching | biological process | CDC42, CORO1B, ABL1 |
| actin filament bundle assembly | biological process | EZR, CDC42, AIF1, CORO1B, PAWR, BAIAP2L1, BAIAP2, DPYSL3, PLS1, SWAP70, RHOD, AIF1L, USH1C, LIMA1, NEDD9, FSCN3, ESPN, EPS8, ACTN1, ADD3, MYO1B, ADD2, LCP1, ADD1, DMTN, MARCKS, MICAL1, FSCN2, SHROOM2, ESPNL, ACTN4, FAM107A, FSCN1, BAIAP2L2, FMN2 |
| actin filament bundle organization | biological process | RFLNB, RFLNA |
| actin filament bundle retrograde transport | biological process | SHTN1 |
| actin filament capping | biological process | CAPZA3, SCIN, SPTBN5, CAPZA1, SPTBN1, SPTBN2, CAPZA2, RDX, CAPZB, SPTB, CAPG, SPTAN1, AVIL, DMTN, SPTBN4, VIL1 |
| actin filament debranching | biological process | GMFB, GMFG |
| actin filament depolymerization | biological process | DSTN, PPP1R9B, WDR1, CFL2, MICAL3, TWF2, MICAL2, MICAL1, VIL1 |
| actin filament fragmentation | biological process | DSTN, WDR1, CFL2 |
| actin filament network formation | biological process | COBL, ARPC5, PLS1, ACTN1, CARMIL1, LCP1, FHOD3, CARMIL2, FHOD1 |
| actin filament organization | biological process | BCL2, TMSB4X, CDC42, WASL, KASH5, SHROOM3, CORO1B, ACTR3, DIAPH2, MYOM2, FAT1, RHOU, PPP1R9B, TPM3, TMSB15A, TMSB15B, NCK1, MYO5C, CORO1C, CCL11, TPM4, NCK2, BCAR1, ARF1, RHOG, CFL2, MYO5A, TMSB4Y, EMP2, ACTC1, MYOM3, CORO6, DIAPH1, CAV3, CGNL1, ARHGAP17, POF1B, TTN, CDC42EP2, ALDOA, RHOF, MYO6, FSCN3, SORBS3, SORBS2, RHOQ, TMSB10, DLG1, RUFY3, RHOBTB3, ACTN1, RAC1, SPIRE1, ELMO2, EVL, MYO1B, RAC2, ARHGEF2, ARHGAP6, CARMIL1, MAD2L2, MYO5B, PLA2G1B, ACTR2, TRIOBP, TMOD3, CD2AP, PPP1R9A, MYO1F, ELMO3, SRF, ARHGAP25, RAC3, AVIL, WAS, CORO7, PDLIM3, MPRIP, SAMD14, RHOJ, MYO1C, CORO1A, FHOD3, ARHGAP12, RHOV, TMOD4, TPM2, PPARGC1B, KPTN, FSCN2, MYO7A, SHROOM2, LMOD2, MYO7B, SH3BP1, MYO1G, HIP1R, TMOD1, MYOM1, FSCN1, BIN3, MYO1D, LMOD1, PTK2B, ELMO1, SH3KBP1, PACSIN1, ACTR3C, ACTR3B, XIRP1 |
| actin filament polymerization | biological process | AIF1, JAK2, COBL, WASF3, WASHC3, CTTN, DIAPH1, RAC1, SPIRE1, ARHGAP6, MSRB2, WASF1, HCLS1, MSRB1, PREX1, WAS, CORO7, ARPC4, ANG, LMOD2, FAM107A, CATIP, MICALL2, TTC17, VIL1, DIAPH3 |
| actin filament reorganization | biological process | env, GDPD2, BCAR1, NEDD9, EFS, DMTN |
| actin filament reorganization involved in cell cycle | biological process | ARAP1 |
| actin filament severing | biological process | DSTN, SCIN, SRGAP2, CAPG, FLII, AVIL, FMNL1, VIL1 |
| actin filament uncapping | biological process | ACTN2 |
| actin filament-based movement | biological process | WIPF3, MYH10, MYH14, WIPF1, MYO5A, ACTC1, MYO6, WASF2, MYO1B, TIGD5, WIPF2, WAS, MYH9, MYH3, MYH6, MYO7A, MYO9B |
| actin filament-based process | biological process | ACAP2, ELMO1 |
| actin modification | biological process | SETD3, NAA80, TRIOBP |
| actin nucleation | biological process | SCIN, SPIRE1, EVL, ARPC4, LMOD2, SPIRE2, LMOD1, FMN1, VIL1 |
| actin polymerization or depolymerization | biological process | GHRL, WASL, DSTN, SCIN, SVIL, VASP, WIPF1, ABI2, GHSR, EVL, ABI1, ENAH, CAPG, FLII, AVIL, WAS, CAP2, VIL1, CAP1 |
| actin polymerization-dependent cell motility | biological process | ACTR3, ARPC3, JMY, EPS8, ENAH, NCKAP1L |
| actin rod assembly | biological process | HSP90B1, PDXP |
| actin ubiquitination | biological process | TRIM32 |
| actin-mediated cell contraction | biological process | EMP2, ACTC1, PARVA, PDPN |
| actin-myosin filament sliding | biological process | ACTC1 |
| action potential | biological process | SRI, GJD2, KCNMB3, KCND2, USP53, KCNB1, GNA11, GNAQ, CACNA1G, SCN1A, CLN3, GLRA1, CHRNB2, CHRNA4, KCNMB4, CHRNB4, AKAP6 |
| activated T cell proliferation | biological process | BTN3A1, SATB1, ABL1, CRTAM |
| activation of adenylate cyclase activity | biological process | LHCGR, FSHR, GNAS, ADCY2, EDNRA, ACR, RAF1, P2RY11, LGR4, TMIGD3, RXFP1, ADRB2, ADRB3, GIPR, GHRHR, CALM3, GLP1R, ADCY6, ADCY8, ADCY7, ADORA3, ADCY9, CRHR1, CALCA, AVPR2, DRD1, ADCY4, ADRB1, TSHR, LGR5, ADCY5, ADORA2B, CALCR, CAP2, VIPR2, CAP1 |
| activation of blood coagulation via clotting cascade | biological process | F3, ANO6 |
| activation of cysteine-type endopeptidase activity | biological process | BAK1, CASP8, BAD, LGMN, FADD, CYFIP2, RIPK2, IFI16, ASPH, PERP, PYCARD, GRIN2A, CIDEB |
| activation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | TNF, FAS, CASP1, TNFSF10, BAX, BAK1, CASP3, FASLG, CASP9, CASP8, CDKN2A, F3, BAD, XDH, NGF, HSPD1, F2R, PPARG, S100A9, BEX3, IFT57, JAK2, TNFSF15, DAP, SLC22A2, PDCD2, RPS27L, ANP32B, BCL2L11, SNCA, RACK1, NKX3-1, DLC1, TNFRSF10B, FADD, AIFM1, BID, CFLAR, COL4A3, PDCD6, FAM162A, NLRP3, SENP1, MTCH1, PML, NLRP1, BOK, S100A8, DIABLO, CASP10, ATP2A3, CARD8, NLRP12, TRADD, PIDD1, RET, CASP8AP2, PYCARD, TNFRSF10A, CCK, MUL1, LCK, NGFR, HSPE1, BCL2L10, NOD1, CTSH, HIP1R, TRAF2, SMAD3, BBC3, CRADD, KHDC1, ACER2, EIF2AK3, ROBO1 |
| activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c | biological process | BAX, BAK1, CASP3, CASP9, CYCS, BOK, DIABLO |
| activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological process | FAS, TNFSF10, BAX, FASLG, CASP8, JAK2, SMAD3 |
| activation of GTPase activity | biological process | TBC1D15, EVI5, MTSS2, USP6NL, FOXJ1, ARHGEF10, SYDE2, RALGAPA1, TBCK, CORO1C, TBC1D1, RABGAP1, BCR, ABR, TSC1, RASGRP1, ARHGEF5, RALGAPB, ARHGAP45, RHOG, ARHGAP22, ARHGAP24, RCC2, TBC1D30, EIF5, TBC1D10C, PIP5K1A, TBC1D22B, ADPRH, SCRIB, TBC1D13, RAPGEF1, TBC1D3D, TBC1D3I, TBC1D3E, TBC1D3F, TBC1D3L, NEDD9, RALGAPA2, TBC1D26, TIAM1, DOCK7, TBC1D4, TBC1D8, TBC1D22A, ECT2, TBC1D12, TBC1D28, TBC1D10B, ARHGAP29, PLEKHG4, RABGAP1L, SGSM2, TBC1D9, BCAS3, EPHA1, TBC1D9B, NGEF, EPHA2, CCR7, ARHGAP25, TBC1D16, EVI5L, TAX1BP3, CCDC125, TBC1D5, NTF3, CRK, APC2, GRTP1, TBC1D7, GMIP, AKT2, ARHGEF16, SGSM3, TBC1D2, USP6, RASGRF1, TBC1D25, TBC1D17, ARHGAP42, PTK2B, TIAM2, TBC1D14, CCL21, CRKL, GPR65, ARHGEF26 |
| activation of immune response | biological process | TREX1, HMSD |
| activation of innate immune response | biological process | TLR4, SIN3A, MATR3, TBK1, XRCC5, PSPC1, SFPQ, MNDA, ZCCHC3, XRCC6, NONO, ZBP1, HMGB1, PRKDC, AIM2, IFI16, RBM14, STING1, CGAS, PQBP1, PYCARD, HEXIM1, PYHIN1, MAVS, TRIM5 |
| activation of JAK2 kinase activity | biological process | PRLR |
| activation of Janus kinase activity | biological process | JAK2, PIBF1, GHR, PTK2B |
| activation of JNKK activity | biological process | ERCC6, MAP3K13, MAP3K12, TNIK, MAP3K9, MAP3K10 |
| activation of JUN kinase activity | biological process | MAP4K2, MAP4K1, DAB2IP, MAP3K20, ERCC6, SYK, WNT7B, BIRC7, TAOK2, MAP3K6, MAP2K4, DBNL, MAP2K7, HACD3, MAP3K13, MAP3K12, ERN1, MAP3K9, MAP3K5, MDFIC, TAOK1, PTPN1, MAP3K2, MAP3K10, CCL19, PKN1, MUL1, ERN2 |
| activation of MAPK activity | biological process | SOD1, EGF, TNF, IL1B, TGFB3, CDK1, MAPK3, MAPK1, GHRL, TLR4, IGF1, INSR, KIT, HGF, FPR1, NRG1, PTPN11, DUSP6, PROK2, SAA1, PROK1, MAPK14, CXCR4, GRM4, KARS1, CD74, TDGF1, SHC1, MAPK11, ALK, MAP3K7, TGFA, IRAK1, CD81, UBE2N, RPS27A, IRAK2, IQGAP3, SYK, CSPG4, MAPKAPK5, C5, TAB1, TAOK2, NOD2, THBS1, PHB2, MAP2K4, MAP2K3, MAP2K7, PTPRC, CHRNA7, DUSP5, PLCE1, IKBKG, MAP2K2, UBE2V1, TAB2, GHR, RIPK2, MAP3K5, TRAF6, S1PR2, UBC, GNG3, PEA15, AVPI1, TAOK1, FRS2, PLA2G1B, UBA52, TAB3, MAP3K2, MAP2K6, MAPKAPK3, LPAR1, P2RX7, ADRA2B, MAP2K1, DUSP7, PAK3, MOS, RET, PDE6G, MAP2K5, INAVA, MADD, LPAR3, BMP2, FGF2, NTF3, UBB, ADORA2B, DUSP9, NOD1, SHC2, MUC20, AGT, FGF1, MAPK10, DRD4, IGFBP6, CRKL, LRRK2, FGF10, C5AR1, GRM1 |
| activation of MAPKK activity | biological process | EGFR, EGF, FLT1, BMP4, KISS1R, NGF, RAF1, F2R, RAP1A, NTRK1, GADD45B, LAMTOR3, JAK2, MAP3K4, MAP3K7, MAP3K20, BRAF, MAP3K8, TAOK2, MAP3K15, MAP3K6, TAOK3, PSEN1, RAPGEF1, MAP3K3, KIDINS220, MAP3K13, MAP3K12, MAP3K9, ADAM9, MAP3K5, TGFBR1, TAOK1, FRS2, MAP3K2, MAP3K10, EIF2AK2, CARTPT, MAP3K14, MOS, CRK, CRKL, MAP3K1, LRRK2, GRM1 |
| activation of MAPKKK activity | biological process | TNF, GADD45B, MAP4K2, MAP4K1, DAB2IP, TAB1, MAP4K3, GADD45A, TRAF7, KSR1 |
| activation of meiosis | biological process | MSX1, MSX2 |
| activation of NF-kappaB-inducing kinase activity | biological process | MAS1, MALT1, TNFSF15, COPS8, ZFP91, MAP3K7, IRAK1, CHI3L1, TNFRSF10B, CARD10, TIRAP, TRAF6, TRAF4, TNFRSF10A, TLR3, TRAF2, CARD14, TLR6 |
| activation of phospholipase A2 activity | biological process | PLA2G1B, ANG |
| activation of phospholipase A2 activity by calcium-mediated signaling | biological process | EGFR, NMUR2 |
| activation of phospholipase C activity | biological process | EGFR, EDNRA, NTF4, ITK, RASGRP4, CD86, PLCB2, NTRK2, PHB2, P2RY12, ADRA1A, GNAQ, ARHGAP6, LPAR1, NMUR1, AVPR1B, GNA15, GPR55, ADCYAP1R1, S1PR4, ANG, CALCR, LPAR2, P2RY6, AGT, TXK, C5AR1, HTR2B |
| activation of phospholipase D activity | biological process | CCL5, ARF4, HPCA, ARL1, PRKCZ |
| activation of plasma proteins involved in acute inflammatory response | biological process | F3 |
| activation of protein kinase A activity | biological process | ADCY2, PRKAR2A, FBN1, PRKACB, PRRC1, UCN, ADCY6, ADCY8, ADCY7, PRKACG, ADCY9, PRKAR2B, ADCY4, PRKAR1B, ADCY5 |
| activation of protein kinase activity | biological process | VEGFA, INSR, PIK3CA, PRNP, BORA, CAB39, STK3, MAP3K4, MAP4K2, NEK1, STK4, MARK2, DUSP19, MAP4K1, PDGFB, STK25, KIF14, PRKAG2, RPLP1, STRADB, MAP3K8, CCDC88A, ADNP, TAOK2, STK10, ACVR2B, MAP4K3, MAP4K4, EMP2, WNK1, TPX2, MAP2K4, MAP2K3, TAOK3, MAP2K7, AXIN1, ADRA2A, PAK6, MAP3K3, ITGB3, MAP2K2, TGFB2, DLG1, CDK5R1, STRADA, ECT2, TNIK, MAP3K19, SPDYA, SLK, STK26, TRAF6, TOM1L1, NEK4, PRKCD, TAOK1, AGAP2, CLSPN, GPRC5A, RGCC, MAP3K2, SLC11A1, MAP2K6, DBF4B, GPRC5B, WNT11, CALCA, MAP2K1, MAP3K14, RIPK3, PAK3, OXSR1, PAK4, TGFBR2, NCKAP1L, MAP2K5, GPRC5C, PAK5, EPO, DRD2, MAPK8IP2, RPTOR, MINK1, GPRC5D, ATG13, MAP3K1 |
| activation of protein kinase B activity | biological process | GAS6, PARK7, IGF1, INSR, SRC, NRG1, PDGFB, CCDC88A, OSBPL8, ADRA2A, PINK1, MAPKAP1, ITGB1BP1, PRKCZ, ADRA2B, MT3, MLST8, PRR5, NTF3, ANG, ADRA2C, PDPK1, INS, FGF1 |
| activation of protein kinase C activity | biological process | LEP, CD86, PHB2, ABL1 |
| activation of signaling protein activity involved in unfolded protein response | biological process | BAX, BAK1, HSPA5 |
| activation of store-operated calcium channel activity | biological process | STIMATE, CRACR2A, STIM2, ASPH, PLCG2, STIM1 |
| activation of transmembrane receptor protein tyrosine kinase activity | biological process | EGF, PRLR, NRG1, NRG3, PILRB, ADRB2, EFNA5, ANGPT4, ANGPT1, CHRNA3, PDGFC, DGKQ, GREM1 |
| activation-induced cell death of T cells | biological process | FAS, AKT1, IL2RA, SIVA1 |
| active induction of host immune response by virus | biological process | TGFB1 |
| activin receptor signaling pathway | biological process | INHBA, BMPR2, ACVR1B, ACVR1, ACVR2B, HJV, ACVR1C, TGFBR1, SMAD2, ACVR2A, TGFBR2, ACVRL1, GDF7, GDF2, SMAD3 |
| actomyosin contractile ring assembly | biological process | ANLN, PDCD6IP, RTKN, KIF23 |
| actomyosin structure organization | biological process | MYH10, FRMD6, TJP1, EPB41L1, CIT, MYH14, CNN2, CNN3, EPB41L3, ROCK2, ACTC1, ROCK1, PHACTR1, MYO18A, EPB41L5, FRMD3, F11R, EPB41L4B, CNN1, LIMCH1, ALKBH4, CDC42BPB, MYH9, FRMD5, CDC42BPG, EPB41, EPB41L2 |
| acute inflammatory response | biological process | OGG1, EIF2AK1, ACVR1, NUPR1, TREM1, PTGES, B4GALT1, S100A8, TNFSF4, VNN1, HPR, HP |
| acute inflammatory response to antigenic stimulus | biological process | ICAM1, ELANE, CXCR2, NPFF, CD6, IL31RA |
| acute-phase response | biological process | IL6, IL6R, IL1RN, HIF1A, SERPINA1, CRP, STAT3, HFE, FN1, SERPINA3, SAA1, REG3A, SAA4, ASS1, ORM1, SERPINF2, REG3G, SAA2, APOL2, PLSCR1, ORM2, F8, TFR2, HAMP, HP, APCS, MBL2, ITIH4, CD163, F2, INS, EPO, LBP, SIGIRR, AHSG |
| acyl carnitine transmembrane transport | biological process | SLC25A48, SLC25A29, SLC25A20, SLC25A47 |
| acyl carnitine transport | biological process | SLC25A48, SLC25A29, SLC25A47 |
| acyl-CoA metabolic process | biological process | MLYCD, DBI, GLYAT, BAAT, THEM5, ACOT13, GCDH, ACSM2A, THEM4, ACOT9, ACOT7, ACSM5, GPAM, ACSM3, HMGCL, ACOT2, ACBD6, ACOT11, ACSM1, ACSF2, ACOT4, OXSM |
| acylglycerol acyl-chain remodeling | biological process | DGAT2, DGAT1, PNPLA3, DGAT2L6, MGLL |
| acylglycerol catabolic process | biological process | ABHD12, ABHD2, ABHD6, MGLL |
| acylglycerol homeostasis | biological process | ANGPTL3, APOA5 |
| adaptive immune response | biological process | IFNG, RAG1, IFNA1, HLA-E, CD79A, CD46, IL2, C1QBP, CAMK4, CD8A, FGL1, CLEC6A, FBXO38, ERAP1, JAK2, ERAP2, CD74, GPR183, BCL10, CD79B, EOMES, CTSL, CD1C, CD81, LAMP3, JAM3, ANXA1, IFNA8, SYK, TAP1, BTLA, FCAMR, TSC1, HAVCR2, DCLRE1C, LAT2, CTLA4, TNFRSF17, TAP2, ITK, CLEC4C, CD274, PRDM1, HLA-DQA2, HLA-DMB, CD86, ZAP70, CD209, BTN3A1, SH2D1B, NEDD4, DBNL, IFNA10, FGB, HLA-DOA, HMGB1, TEC, SKAP1, ZNF683, PRKCB, CD3E, C17orf99, FCRL4, CRACR2A, CD3G, BTN3A2, CD247, MICB, RIPK2, TFE3, HLA-DPA1, RNF19B, LYN, ALCAM, PDCD1LG2, BTN3A3, CTSS, PIK3CG, BTK, TNFRSF14, SLAMF6, CD244, CRTAM, LAIR1, CLEC10A, CD4, VTCN1, TNFRSF13C, PRKD2, LIME1, PAG1, CLEC4A, TNFRSF11A, PIK3CD, TNFRSF21, IFNA2, IFNA14, FGA, CD1E, MARCHF8, LAT, LILRA1, CD160, CD6, SLAMF1, TRPM4, CLEC4D, CD84, LILRB5, TFEB, CSK, OTUD7B, LILRA3, LILRB4, RNF125, SLAMF7, TREX1, TNFRSF13B, ICOSLG, CTSH, JAK3, MCOLN1, MYO1G, IFNW1, CD19, PRR7, UNC93B1, CD8B, ADGRE1, PTK2B, MCOLN2, THEMIS, CD7, TXK, TRAT1, SIGLEC10, LY9, HLA-DPB1, BTNL8, LAX1, SIT1 |
| adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | biological process | TGFB1 |
| adaptive thermogenesis | biological process | HNRNPU, UCP3, THADA, PPARGC1A, UCP1, UCP2, SORL1, ZBTB7B |
| adenine biosynthetic process | biological process | GART |
| adenine metabolic process | biological process | APRT, HPRT1 |
| adenine nucleotide transport | biological process | SLC25A5, SLC25A23 |
| adenine salvage | biological process | APRT, HPRT1 |
| adenine transport | biological process | SLC25A4, SLC25A5, SLC29A2 |
| adenohypophysis development | biological process | PROP1, SOX2, HES1, GHRHR, GSX1, DRD2, SLC6A3 |
| adenosine 5'-(hexahydrogen pentaphosphate) catabolic process | biological process | NUDT4, NUDT3 |
| adenosine biosynthetic process | biological process | NT5E |
| adenosine catabolic process | biological process | CECR1, ADAL, ADA |
| adenosine metabolic process | biological process | ACPP, NT5C1A, PTGDR, NT5C1B, ADA, NT5C2 |
| adenosine to inosine editing | biological process | ADARB1, ADAR, NUDT16, ADAD2, ADARB2 |
| adenosine transport | biological process | SLC28A2, SLC29A2, SLC29A1 |
| adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | GNAS, RAPGEF2, ADRB2, ADRB3, ADRA2A, ADRA1A, ADCY9, GPR101, ADRA2B, DRD3, DRD1, ADRA1D, ADRB1, ADRA1B, ADRA2C, DRD2 |
| adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | biological process | PLN, AKAP13 |
| adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate | biological process | PDE4D |
| adenylate cyclase-activating dopamine receptor signaling pathway | biological process | GNAS, SLC9A3R1, GNB1, PTGER1, GNAL, GNG2, DRD3, DRD1, ADCY5 |
| adenylate cyclase-activating G-protein coupled receptor signaling pathway | biological process | LHCGR, FSHR, GNAS, RXFP2, ADCY2, IAPP, ADGRL1, GNAI2, LGR4, CXCL11, PTH1R, CALCRL, MC2R, GPR119, RXFP1, RAMP2, S1PR1, ADRB2, ADRB3, PTGER2, RIT2, PF4, PTGER1, GHRHR, ADRA2A, GPR4, GCGR, ADGRF1, GNAL, ADGRB3, CNR1, PTGER3, GLP1R, ADCY6, ADCY8, ADGRL2, GNAQ, ADCY7, S1PR2, PTGER4, GPR26, NME2, ADGRB2, ADCY9, CRHR1, CXCR3, LPAR1, ADGRE3, RAMP3, CALCA, S1PR5, ADGRB1, PTHLH, DRD1, ADGRG3, ADCY4, LPAR3, ADRB1, CALCB, TSHR, PTGIR, ADGRG5, GPR161, UCN3, S1PR3, GALR1, UCN2, RAMP1, LGR5, ADCY5, S1PR4, ADORA2B, CALCR, ADGRG7, GPHA2, LPAR2, GPR12, ADGRD1, ADGRE2, TBXA2R, ADORA2A, ADGRE5, ADGRE1, ADGRL3, MC1R, GPR65, CXCL10, MC3R, GPER1, ADGRL4 |
| adenylate cyclase-inhibiting adrenergic receptor signaling pathway | biological process | ADRA2A |
| adenylate cyclase-inhibiting dopamine receptor signaling pathway | biological process | DRD3, ADCY5, DRD2, DRD4 |
| adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway | biological process | CHRM3, HRH4, HRH3, CHRM4, CHRM1, CHRM5, CHRM2 |
| adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway | biological process | GRM3, GRM4, GRM8, GRIK3, GRM2, GRM6, GRM7 |
| adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | biological process | INSL3, RXFP2, ADCY2, GNAI1, AKAP12, GNAI2, GPR37L1, GNAI3, GRM8, GNAZ, PSAP, S1PR1, MTNR1A, MARCO, CORT, P2RY12, ADRA2A, NPR3, MCHR1, GNAL, ADCY6, ADCY8, ADCY7, HTR1E, OPRD1, NPY1R, RGS1, FFAR3, ADCY9, GPR176, LPAR1, PTGDR2, P2RY1, GABBR1, PALM, FPR2, HTR1B, ADCY4, EDN1, S1PR3, PDE2A, ADCY5, AKAP5, RIC8A, OPRL1, GRM7, OPRK1, OXER1 |
| adenylate cyclase-inhibiting opioid receptor signaling pathway | biological process | OPRK1 |
| adenylate cyclase-inhibiting serotonin receptor signaling pathway | biological process | HTR1E, HTR1B, HTR5A |
| adenylate cyclase-modulating G-protein coupled receptor signaling pathway | biological process | RXFP2, ADCY2, GNAO1, GNAI1, FPR1, GRK5, GNAI2, CYSLTR1, PTH1R, CALCRL, PRKACB, GNAI3, GNAZ, GNAT2, ADRB2, ADRB3, GIPR, GHRHR, P2RY12, ADRA2A, ADRA1A, GCGR, GNAL, LTB4R, CNR1, GLP1R, GNA12, GNA11, WASF2, GNAQ, PTGER4, GNA14, CRHR1, CRHR2, GPR101, ADRA2B, AVPR2, DRD3, PTH2R, GLP2R, DRD1, ADRA1D, GNA15, ADCY4, ADRB1, ADRA1B, ADCYAP1R1, SCTR, CACNA1D, ADRA2C, CALCR, LTB4R2, DRD2, GALR3, ADORA2A, CHRM2, VIPR2, CCR3, MC3R |
| adherens junction assembly | biological process | CTNNB1, JAM3, HIPK1, RAMP2, VCL, TBCD, ZNF703, PIP5K1C |
| adherens junction maintenance | biological process | TJP1, RASSF8, INAVA |
| adherens junction organization | biological process | CTNNB1, SRC, CDH1, CDC42, CDH18, NUMBL, CDH7, CTNNA1, NUMB, CDH10, CTNND1, CDH19, DSP, CDH12, CDH17, NECTIN4, EPHA4, CDH6, NECTIN1, CDH9, CDH5, EFNB2, CDH8, CDH11, CDH13, JUP, PVR, ANG, CDH3, CSK, CDH4, CDH15, CADM3, CDH24, CDH23, CDHR3, CDH26, CADM2, AFDN |
| adhesion of symbiont to host | biological process | ICAM1, SCARB1 |
| adiponectin-activated signaling pathway | biological process | CSNK2B, ADIPOR1, ACSL1, SLC27A1, ADIPOR2, APPL2, APPL1 |
| adipose tissue development | biological process | ACAT1, LEP, PIK3CA, EBF2, AACS, PGRMC2, DYRK1B, XBP1, PPARD, PPARGC1A, ARID5B, SELENOM, NAMPT, OXCT1, SPART, ATF2, LRP5, ID2, AMER1, SPTLC2, UBB, SLC25A25, SH3PXD2B, LRP5L, RORC, UMODL1, ZNF516, PAXIP1 |
| ADP biosynthetic process | biological process | AK2, AK4, AK1, AK3 |
| ADP catabolic process | biological process | NUDT9 |
| ADP metabolic process | biological process | BAD, AMPD3 |
| ADP transport | biological process | SLC25A4, SLC25A6, SLC25A5, SLC25A17, SLC25A31, SLC25A42 |
| adrenal chromaffin cell differentiation | biological process | ASCL1, INSM1 |
| adrenal cortex formation | biological process | WT1, CITED2 |
| adrenal gland development | biological process | WT1, NR5A1, CYP17A1, NR0B1, INSR, WNT4, ARID5B, FSTL3, CRH, MDK, APOA1, PBX1, SMAD2, WNT11, PDGFRB, SALL1, PDGFRA, STRA6, NF1, SMAD3 |
| adrenergic receptor signaling pathway | biological process | ADRB2, ADRA2A, PDE4D, AKAP13, ADRA2B, ADRA2C |
| adrenomedullin receptor signaling pathway | biological process | CALCRL, RAMP2, RAMP3 |
| adult behavior | biological process | PTEN, PCDH17, ATP6V1B1, BBS2, NLGN4X, ALK, TPGS1, SLC1A2, NRXN1, MAFG, GABRG2, BBS4, NRXN2, SLITRK5, SHANK2, NRXN3, SLITRK1, CNTNAP2, SPTBN2, PAX5, ADAM2, SEPTIN5, NR4A3, DRD2, SHANK1, SPTBN4, UNC79 |
| adult feeding behavior | biological process | GHRL, LEP, ASIP, PRLHR, GHSR, NPY, BRS3, IFT80, CARTPT, DMBX1 |
| adult heart development | biological process | MYH7, GJA1, CHD7, MYH10, TCAP, ADRA1A, MEF2D, SCUBE1, APLNR, MNAT1, NKX2-5, MYH6, HAND2 |
| adult locomotory behavior | biological process | APP, PARK7, GDNF, ARCN1, FGF12, PUM1, KALRN, PPT1, NTAN1, GRIN1, INPP5F, CSTB, PREX2, HTRA2, PRKN, PBX3, TSC1, NTF4, WDR47, NR4A2, CHL1, CNP, ATP1A2, MECP2, EPS8, HIPK2, SLITRK6, ADAM22, OPRD1, HOXD10, ID2, EN1, DMBX1, SEZ6L, GIGYF2, HOXB8, LGI4, NTSR1, TMOD1, CXCL12, SEZ6, BTBD9, GRIN2D, DRD4, SNCG, FOXA2 |
| adult walking behavior | biological process | TRH, CHD7, KCNJ10, FXN, ZMPSTE24, ABHD12, CTNS, HTRA2, OXR1, CNTN2, KLHL1, HIPK2, DMRT3, GBX1, NPC1, SCN1A, EPHA4, GLRA1, DRD1, EFNB3, DRD2, ARRB2, SPTBN4, UCHL1 |
| aerobic electron transport chain | biological process | MT-CO3 |
| aerobic respiration | biological process | PANK2, CAT, COX10, MT-CO1, SDHB, FXN, UQCRB, MDH2, UQCRC2, COX6A1, ATP5F1D, MTFR1L, BLOC1S1, UCN, ADSL, UQCRHL, SLC25A14, SURF1, UQCRC1, MTFR1, MTFR2, UQCR10, NDUFS8, SDHC, UQCRH, OXA1L, ME3, COX6A2, NDUFS7, MT-ND1 |
| aflatoxin metabolic process | biological process | CYP2W1 |
| age-dependent response to reactive oxygen species | biological process | SOD2 |
| aggrephagy | biological process | ATG5, SQSTM1, WDR81, ACBD5, WDFY3, MAP1LC3C |
| aggresome assembly | biological process | TRIM37, PRKN, UBD, BAG3, HDAC6 |
| aggressive behavior | biological process | PENK |
| aging | biological process | SOD1, TIMP1, TGFB1, IL1B, AMH, CYP1A1, IL6, DCN, TGFB3, TNFRSF1B, IL10, PTGS1, FAS, ADM, BAX, BAK1, OGG1, BGLAP, ERCC2, DNMT1, AKT1, GSK3B, CASP9, MBD1, GNRH1, GNAO1, CLU, F3, EDNRA, STAT3, PTEN, CAT, IGF1, CCL5, POLG, MMP7, APEX1, TACR3, MT-CO1, MT-ATP6, NTRK1, SIN3A, MT-ND4, TIMP2, CX3CL1, CCN2, TYMS, CANX, IL15, SCAP, KYNU, SLC12A2, RGN, KCNMB1, CARM1, PPP1R9B, CRYAB, RPN2, IGFBP1, CTNNA1, IRAK1, PTH1R, GCLC, CTSC, LOXL2, HTRA2, ASS1, UCP3, KRTAP4-5, GLRX2, PPARGC1A, NQO1, FBXO4, HMGCR, EEF2, ENDOG, OPA1, COL4A2, NAMPT, RELA, NUDT1, NAPEPLD, APOD, ADRA1A, CASP2, EDNRB, NFKB2, CACYBP, CNP, CNR1, PAX5, EIF2S1, GRB2, PPP3CA, ATP8A2, FOXG1, LITAF, PDE4D, ADA, ABAT, FOS, ENO3, PPP1R9A, PITX3, MBD3, CALCA, ITGB2, IGFBP2, SREBF1, P2RY1, HAMP, LRP1, EIF2B5, MPO, MME, PDGFRB, TGFBR2, KRT83, TPRA1, ATP2B1, FOXO4, DAG1, GJB6, CLDN1, C1QA, SERPING1, POLB, KL, FOXO3, JUND, IGFBP5, SERPINF1, KRTAP4-8, SRR, EPO, KRT14, LONP1, SLC6A3, BCL2A1, AURKB, SLC32A1, AGT, AMFR, PENK, NPY5R |
| agmatine biosynthetic process | biological process | AGMAT, AZIN2 |
| alanine transport | biological process | SLC38A2, SLC6A17 |
| alanyl-tRNA aminoacylation | biological process | AARS1, AARS2, AARSD1 |
| alcohol catabolic process | biological process | ADH4 |
| alcohol metabolic process | biological process | ADH4, ADH1A, ALDH2, ALDH3B1 |
| aldehyde catabolic process | biological process | AKR1A1, ALDH3B1 |
| aldosterone biosynthetic process | biological process | CYP11B1, CYP11B2, CACNA1H |
| alkaloid catabolic process | biological process | CYP3A5, CYP2D6 |
| alkaloid metabolic process | biological process | CYP1A2, CYP2D6 |
| allantoin biosynthetic process | biological process | URAD |
| allantoin catabolic process | biological process | ALLC |
| allantois development | biological process | BMP5 |
| alpha-amino acid metabolic process | biological process | AADAT |
| alpha-beta T cell activation | biological process | INS, DOCK2 |
| alpha-beta T cell differentiation | biological process | TCF7, ANXA1, BCL11B, ABL1, LEF1, PRR7 |
| alpha-beta T cell proliferation | biological process | DOCK2 |
| alpha-glucoside transport | biological process | SLC5A1, SLC5A2 |
| alpha-ketoglutarate transport | biological process | SLC25A11, SLC25A21 |
| alpha-linolenic acid metabolic process | biological process | HSD17B4, SCP2, ACSL1, ACAA1, ELOVL2, ELOVL5, FADS1, ELOVL1, ELOVL3, ABCD1, FADS2, ACOX1 |
| alpha-tubulin acetylation | biological process | KAT2A |
| alternative mRNA splicing, via spliceosome | biological process | SRSF6, HNRNPM, SFPQ, SLU7, CDK13, RSRC1, CELF4, PUF60, RBM17, DDX17, PQBP1, SFSWAP, ESRP2, SCNM1 |
| alveolar primary septum development | biological process | STRA6 |
| alveolar secondary septum development | biological process | FOXA1 |
| amacrine cell differentiation | biological process | NEUROD4, NEUROD1, FOXN4, PTF1A |
| ameboidal-type cell migration | biological process | PDXDC1, WASF2, CAP1, CENPV |
| amelogenesis | biological process | ITGA6, CSF3R, SLC24A4, MMP20, ATF2, PERP, RELT, KLK5, KLK4 |
| amide transport | biological process | SLC47A1 |
| amine biosynthetic process | biological process | SULT1A2 |
| amine metabolic process | biological process | CYP1A1, SULT1A1, AOC2, VCAM1, SULT1C2, AOC1, AOC3, INMT |
| amine transport | biological process | SLC22A2, AQP9, SLC22A16, RHCG |
| aminergic neurotransmitter loading into synaptic vesicle | biological process | DDC, TH, SLC18A2 |
| amino acid activation for nonribosomal peptide biosynthetic process | biological process | AASDH |
| amino acid homeostasis | biological process | SLC66A1 |
| amino acid import across plasma membrane | biological process | SLC7A1, SLC22A4, SLC7A2 |
| amino acid transmembrane transport | biological process | SLC7A5, SLC6A14, SLC6A20, SLC38A9, SLC6A6, SLC36A4, SLC38A7, SLC38A6, SLC36A1, SLC7A6, SLC38A1, SLC38A11, SLC3A1, SLC6A15, SLC7A8, SLC36A2, SLC38A2, SLC38A10, SLC7A9, SLC36A3, SLC38A4, SLC16A10, SLC7A14, PDPN, SLC43A1, SLC6A12, SLC6A9, SLC38A8, SLC6A19, SLC6A18, SLC43A2, SLC38A5, SLC38A3, SLC32A1, SLC7A4 |
| amino acid transport | biological process | SLC7A5, SLC6A14, SLC6A20, SLC38A9, SLC6A6, SLC1A5, SLC36A4, SLC38A7, SLC38A6, SLC25A48, SLC36A1, SLC1A2, SLC7A6, SLC38A1, SLC1A4, SLC38A11, SLC7A3, SFXN1, SLC17A5, SLC66A1, SLC1A3, SLC3A1, SLC6A15, SLC7A8, SLC36A2, SLC38A2, SLC38A10, SLC7A9, SLC38A4, SLC16A10, SLC7A14, SLC1A6, SLC7A1, SLC25A44, SFXN3, PDPN, SLC7A7, SLC43A1, SLC6A12, SLC6A7, SLC3A2, SLC6A9, SLC25A29, SFXN2, SLC38A8, SLC6A19, SLC6A18, SLC7A10, SLC43A2, SLC38A5, SLC38A3, SFXN5, SLC7A2, SLC7A4, SLC25A47 |
| amino-acid betaine catabolic process | biological process | DMGDH |
| aminoacyl-tRNA metabolism involved in translational fidelity | biological process | IARS1, DTD2, IARS2, DTD1, AARS1, AARS2, LARS1, AARSD1, TARS2, VARS1, LARS2, VARS2 |
| aminophospholipid translocation | biological process | TMEM30B, TMEM30A, ATP8A2, ATP8B1 |
| aminophospholipid transport | biological process | TMEM30B, SCARB2, TMEM30A, ATP11B, ATP8B1 |
| ammonia assimilation cycle | biological process | GLUL |
| ammonium import across plasma membrane | biological process | SLC12A6, SLC12A4, SLC12A7 |
| ammonium transmembrane transport | biological process | SLC12A2, RHBG, AQP1, RHD, RHCG, RHAG, RHCE |
| ammonium transport | biological process | SLC12A2, RHBG, AQP1, RHD, RHCG, RHAG, RHCE |
| AMP biosynthetic process | biological process | ADSS2, ADSS1, ADSL |
| AMP catabolic process | biological process | NT5E, AMPD3 |
| AMP metabolic process | biological process | AK2, AK4, AMPD2, AK1, AK3, AMPD3 |
| AMP phosphorylation | biological process | AK9 |
| AMP salvage | biological process | ADK, APRT |
| AMP transport | biological process | SLC25A17, SLC25A42 |
| AMPA glutamate receptor clustering | biological process | APOE, DLG4 |
| amygdala development | biological process | ESR2, TBR1, ATP1A2, UBA6, NF1 |
| amylin receptor signaling pathway | biological process | IAPP, RAMP2, RAMP3, CALCA, RAMP1, CALCR |
| amyloid fibril formation | biological process | APP, IAPP, RIPK3, SERF1A, CD36 |
| amyloid precursor protein catabolic process | biological process | PSENEN, APH1A, DHCR24, ABCG1, PSEN1, CLN3, PSEN2, BACE1 |
| amyloid precursor protein metabolic process | biological process | PSENEN, APH1A, PSEN1, DLG1, TMCC2, NSG1, KLK6 |
| amyloid-beta clearance | biological process | LDLR, IDE, ITGAM, MARCO, LRP2, TREM2, ITGB2, LRP1, MME, C5AR1 |
| amyloid-beta clearance by cellular catabolic process | biological process | LDLR, IDE, LRP1, MME, ABCA7, LRP4, CD36 |
| amyloid-beta clearance by transcytosis | biological process | RAB11A, RAB5A, PICALM, RAB11B, LRPAP1, CLTC, LRP1 |
| amyloid-beta formation | biological process | DYRK1A, PSENEN, APH1A, PSEN1, ABCA7 |
| amylopectin biosynthetic process | biological process | SLC2A4 |
| anaphase-promoting complex-dependent catabolic process | biological process | CDK1, CCNB1, CDC20, PSMA3, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, BUB3, CDC16, PSMD6, PSMD1, CDC23, PSMD14, PSMD7, ANAPC15, FZR1, PSMB6, RPS27A, ANAPC16, BUB1B, PSMD10, PSMD8, PSMC5, ANAPC5, PSMB4, PSME1, PSMB8, PSMD4, PSMC3, PSMA6, ANAPC7, PLK1, MAD2L1, CDC20B, ANAPC11, PSMD12, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, UBC, CDC27, UBE2D1, UBE2E1, UBA52, PSMD5, PSMF1, PSMB3, CDC26, PSMD3, PSMC1, ANAPC1, UBE2C, ECRG4, UBB, ANAPC4, ANAPC2, FBXO31, AURKB, UBE2S, PSMD13, PSMB10 |
| anastral spindle assembly | biological process | NUMA1 |
| anatomical structure development | biological process | SHH, GLI3, ROR1, TDGF1, HNF4G, SELENOH, EGFL8, WNT4, SPOCK2, NR2E3, NR2F6, WIF1, ATXN1, VWDE, ATXN1L, TAPT1, SIX3, EYA4, CFC1B, NR2C1, PYGO1, SPOCK1, SIX1, SIX2, HNF4A, SIX4, EYA1, EGFL7, SIX6, NR2F1, RXRG, LRP4, GLI2, INSRR, ROR2, SIX5, WNT9A, EYA2, HECTD1, SPARCL1, NR2C2 |
| anatomical structure formation involved in morphogenesis | biological process | NODAL, BMP7, BMP4, GATA4, SHH, TP63, GLI3, FOXA1, GATA3, LHX1, GRB2, DLX6, DLX5, GLI2, WNT3, LHX2, NKX2-1 |
| anatomical structure morphogenesis | biological process | SOX10, F2R, FGF8, FGF3, PKD1, MAS1, DYNLL1, SIAH1, CPM, PAX7, IGF2BP2, TRIM13, TBX10, FAT1, FBN2, SMAD4, MPZL2, EOMES, FBN1, SOX18, DCHS1, HOXB5, FOXA1, ZNF141, MRPL40, HIRA, FBN3, BICD1, SOX12, KRT18, GATA3, PAX8, NEDD8, ERVW-1, DEAF1, TSHB, FOXS1, LHX1, EREG, ONECUT2, SOX11, LYVE1, ANKRD11, SCML2, TPD52, RAC1, EYA4, FOXC2, RCAN3, CLTCL1, SOX4, SOX15, LIG1, FOXI1, SIX2, LST1, PITX3, FGF18, GSC, EN1, FOXB1, SIX4, TH, IER3, MNX1, EFNB2, LBX1, NFE2L1, EYA1, IGF2BP3, PTBP3, CST6, SFRP5, S1PR3, ONECUT1, SOX21, FOXE1, GSC2, PDGFRA, HOXA11, FOXC1, FOXI2, FOXD4L4, TBX6, HOXC13, GPC3, FOXL2, SOX7, FSCN2, TBX19, FGF1, FOXE3, GCM1, FOXD3, PHLDA3, MCAM, HOXA4, PITX2, FOXQ1, FOXA2 |
| anatomical structure regression | biological process | BMP4, SPI1, LEF1, LRP5, CD248 |
| androgen biosynthetic process | biological process | SRD5A2, CYP17A1, HSD17B3, HSD3B1, SRD5A1, HSD3B2, SRD5A3, SCARB1, HSD17B6 |
| androgen catabolic process | biological process | SPP1, HSD17B6, HSD17B11 |
| androgen metabolic process | biological process | ESR1, CYP19A1, SRD5A2, ADM, HSD17B4, SRD5A1, SHH, UGT2B7, DHRS9, PLEKHA1, PPARGC1A, HSD17B8, TIPARP, AKR1D1, AKR1C4 |
| androgen receptor signaling pathway | biological process | AR, BRCA1, NRIP1, FKBP4, CTNNB1, RB1, UBE3A, RWDD1, RNF14, NKX3-1, ZMIZ1, PMEPA1, PLPP1, CST11, ARID1A, DDX17 |
| angiogenesis | biological process | EGF, MMP2, CXCL8, VEGFA, NOS3, PTGS2, IL18, HIF1A, SERPINE1, HMOX1, FLT1, FGFR2, KDR, CIB1, ITGA5, FGFR1, LEP, LEPR, PGF, PTEN, ITGAV, BMP4, PIK3CA, PLAU, FN1, SHH, CYP1B1, PROK2, ANXA2, FGF9, ECM1, PROK1, MAPK14, NOX5, SEMA3E, HOXA3, CCN2, OVOL2, ERAP1, ATP5F1B, CCBE1, PDCD10, NOX1, ZC3H12A, EMC10, HIF3A, SHC1, ADGRA2, FZD8, XBP1, CALCRL, DAB2IP, AGGF1, UBP1, VAV3, TNFSF12, EFNA1, SAT1, EPHB2, TIE1, SOX18, ACVR1, PTK2, PRKD1, JAM3, COL4A1, WARS1, COL8A1, FLT4, SYK, NRXN1, VEZF1, CSPG4, MYDGF, RAMP2, PRKX, SRPK2, ROBO4, SLC12A6, CLIC4, SRPX2, S1PR1, NOTCH1, MFGE8, AMOT, ARHGAP22, ARHGAP24, SH2D2A, COL4A2, YWHAZ, TEK, OTULIN, NUS1, APOLD1, ACKR3, RORA, PLCD1, EPHB1, NRCAM, ATP5IF1, ANGPTL3, APOD, GLUL, ELK3, ANGPT4, AMOTL2, EREG, ANGPTL1, PDGFA, ANGPT1, RNF213, THSD7A, ITGB1BP1, NRP2, PDCD6, PTPRB, HTATIP2, MMP14, GAB1, CEMIP2, WASF2, KRIT1, TSPAN12, HOXA7, VAV2, ACTG1, RBPJ, PDE3B, NAA15, ANGPT2, TGFBR1, VEGFC, AIMP1, TGFBI, S100A7, HSPG2, KLF5, EPAS1, BCAS3, C1GALT1, TMEM100, PARVA, SCG2, EPHA1, PIK3CG, CXCR |
| angiogenesis involved in coronary vascular morphogenesis | biological process | TGFBR1, NRP1 |
| angiogenesis involved in wound healing | biological process | GPX1, CX3CL1, HPSE, PRCP, ETS1, GPR4, ITGB3, B4GALT1, SRF, DAG1 |
| angiotensin catabolic process in blood | biological process | ACE, ACE2 |
| angiotensin maturation | biological process | ACE, ACE2, ATP6AP2, AOPEP, CES1, CTSG, CPA3, MME, CTSZ, ENPEP |
| angiotensin-activated signaling pathway | biological process | CA2, MAS1, AHCYL1, AGTR1, AGTRAP, SLC26A6, AGT, CAMK2A |
| angiotensin-activated signaling pathway involved in heart process | biological process | SRC, CAV1 |
| angiotensin-mediated drinking behavior | biological process | ACE2, AGT |
| animal organ development | biological process | CTNNB1, NRG3, SPRY1, NKX3-2, NRG4, CSHL1, GH2, NRG2, ZEB1, SPRY2, HLX, CSH1, NPPC, TLX1, KAT6A, TLX2, CSH2, SPRY3 |
| animal organ formation | biological process | SHH, HOXA3, NKX3-2, FGF10 |
| animal organ morphogenesis | biological process | TNF, DCN, BCL2, VDR, FGFR2, MAPK3, MAPK1, GSK3B, BMP7, INSR, PROP1, THRB, TP63, GAMT, HOXA3, E2F5, LAMC1, TLE1, E2F4, NEK8, PBX2, HCCS, IL7, ASXL2, ASXL1, LHX3, PHLDA2, EPHB2, BRAF, PBX3, SYK, CUL1, FHL1, ABLIM1, FOXN1, USH2A, NTNG1, GDF11, NTN1, DGCR2, RELA, LAMC2, SFTPB, COL9A1, PDX1, NTN4, ITGA2, LHX1, MEGF8, MEIS3, GREM2, EREG, ONECUT2, PDGFA, PBX1, NDST1, PAX5, EP300, MEGF9, TREH, EVL, NTNG2, TRAF6, VEGFC, HSPG2, PALB2, SMARCC1, SEMA6A, TBX3, ITGAX, TLE2, MEIS1, PITX3, LAMB1, TMEFF1, SYCP2, PBX4, MEIS2, TH, TGFBR2, EFNB2, EGFLAM, RDH10, EYA1, CDX2, CRX, HRAS, BMP2, COL18A1, CDX1, TLE5, FOXF1, LAMB3, PDGFC, LAMC3, SIX6, FGF2, ELN, PDGFRA, LAMA3, HHIP, TMEFF2, NRP1, LAMA5, COMP, GPC3, NTN5, AGRN, NTN3, LY6H, JAG1, PTCH1, LFNG, ETV7, THRA, NBL1, TLE3, LHX4, ASXL3, SLIT3, FLI1, ATRNL1, CRKL, CDX4, FGF10, GREM1, CCL2, NKX2-1, APLP1 |
| animal organ regeneration | biological process | TGFB1, LIF, ADM, BAK1, CDK1, GAS6, GSTP1, PGF, TGFBR3, IGF2R, HGF, PPARG, DDR1, MT-CYB, CCNA2, UPF2, ATIC, ANXA3, F7, PKM, BAAT, CCND1, NOTCH1, LPIN1, PDX1, APOA1, ANGPT2, PTPRU, CDKN1A, LCP1, TGFBR2, PPAT, FPGS, NR4A3, CAD, CXCL12, C5AR1, NNMT |
| animal organ senescence | biological process | ERO1A, PDX1, COMP |
| anion homeostasis | biological process | CPS1 |
| anion transmembrane transport | biological process | ABCC1, SLC26A8, VDAC1, SLC26A4, SLC26A3, SLC24A5, SLC24A4, SLC4A7, SLC1A2, SLC22A9, SLC13A2, SLC9C1, SLC9A2, SLC9A1, LRRC8D, SLC26A9, SLC9A7, SLC4A4, SLC26A5, SLC9A9, SLC26A7, LRRC8C, SLC13A1, SLC9C2, SLC4A2, SLC4A11, SLC24A3, LRRC8B, SLC9A6, SLC26A11, SLC26A1, SLC13A5, SLC4A1, SLC4A3, SLC26A10, SLC26A6, SLC4A10, SLC4A9, SLC24A1, VDAC2 |
| anion transport | biological process | VDAC2, SLC26A8, VDAC1, SLC26A3, SLC17A3, SLC4A7, SLC17A5, SLC26A9, SLC4A4, SLC17A1, SLC26A7, SLC17A6, SLC4A2, SLC4A11, GLRA1, SLC4A8, SLC4A1, SLC4A3, SLC26A6, SLC17A9, SLC17A2, SLC4A10, SLC4A9, SLC17A7 |
| anoikis | biological process | E2F1, TFDP1, MAP3K7, IKBKG, BMF, DAPK2, TSC2 |
| anterior commissure morphogenesis | biological process | NFIB, PLXNA4, TSKU, FBXO45 |
| anterior compartment pattern formation | biological process | PBX3 |
| anterior head development | biological process | DDX10, COL2A1, BMP5, PFAS |
| anterior neural tube closure | biological process | FOLR1 |
| anterior semicircular canal development | biological process | GLI3 |
| anterior/posterior axis specification | biological process | NODAL, CTNNB1, BMP4, CER1, WLS, SKI, PGAP1, LHX1, HEY2, SIX2, CDX2, CDX1, GPC3, WNT3, RNF2, CDX4 |
| anterior/posterior axis specification, embryo | biological process | HOXD8, TDGF1, FRS2, TBX3, FZD5 |
| anterior/posterior axon guidance | biological process | NTN1, DCC, UNC5C, UNC5B, UNC5A |
| anterior/posterior pattern specification | biological process | HNF1B, NODAL, BMPR2, NR2F2, OTX1, SHH, ALDH1A2, HOXA3, GLI3, HOXD13, HOXD8, HOXA6, GRSF1, HOXA2, TULP3, TDGF1, HOXD3, SMAD4, CTNNBIP1, CER1, HOXA5, PCGF2, HES1, HOXB5, BMPR1A, HIPK1, HOXB9, TSHZ1, HES6, BHLHE40, WNT3A, ACVR2B, GDF11, MSX1, LRP6, HOXC9, LHX1, BTG2, EMX2, CDON, SMO, HES7, CELSR1, MLLT3, NEUROD1, YY1, PBX1, HIPK2, HOXC10, VANGL2, HOXB7, BPTF, CFC1B, HOXB6, HOXA7, HOXC6, TGFBR1, HOXD10, SMAD2, HEY2, HOXB4, ACVR2A, HOXC5, ALX4, HES4, LRP5, SFRP2, HOXC11, MSX2, CDX2, CDX1, RING1, HEY1, ZIC3, HOXB3, HOXB8, HOXA11, ZBTB16, SCMH1, HOXC4, RARG, HOXB2, HOXA9, HOXC8, HOXC13, HHEX, TCF15, CYP26C1, GLI2, LRP5L, WNT3, FOXH1, CRKL, CDX4, HOXA10, HOXA4, ALX1, BHLHE41, HES2 |
| anterograde axonal protein transport | biological process | KIF5B, RAB27B, KIF5A, DLG2, HSPB1 |
| anterograde axonal transport | biological process | SOD1, KIF3B, BLOC1S2, RAB21, TRAK2, ARL8B, AP3M1, AP3B1, SNAPIN, AP3S2, AP3D1, AP3M2, AP3S1, AP3B2, KIF1B, BLOC1S1, DTNBP1, TRAK1, BLOC1S4, ARL8A, BLOC1S6, KIF4A, KIF1A, SPG7, HAP1, SPAST, NEFL |
| anterograde axonal transport of mitochondrion | biological process | AGBL4, TRAK2, TRAK1, HAP1 |
| anterograde dendritic transport of mitochondrion | biological process | TRAK2 |
| anterograde dendritic transport of neurotransmitter receptor complex | biological process | KIF5B, KIF17, KIF5A |
| anterograde neuronal dense core vesicle transport | biological process | KIF5B, KIF1C, KIF1B, KIF1A |
| anterograde synaptic vesicle transport | biological process | BLOC1S2, AP3M1, AP3B1, SNAPIN, AP3S2, AP3D1, AP3M2, AP3S1, AP3B2, BLOC1S1, DTNBP1, BLOC1S4, BLOC1S6, TRIM46 |
| anthranilate metabolic process | biological process | HAAO, KYNU |
| anti-Mullerian hormone signaling pathway | biological process | AMHR2 |
| antibacterial humoral response | biological process | ADM, HLA-E, APP, B2M, LTF, SEMG1, SEMG2, PLA2G6, SLPI, TAC1, WFDC9, WFDC10A, H2BC21, CAMP, RPL39, WFDC13, NPY, DEFA3, H2BC12, CTSG, DEFB1, DEFA5, PLA2G1B, PI3, RNASE6, RNASE3, CALCA, DEFA4, BPI, DEFA1, WFDC2, ANG, WFDC3, WFDC12, BPIFA1, WFDC5, H2BC10, RNASE7 |
| antibacterial peptide production | biological process | KLK3 |
| antibiotic metabolic process | biological process | DPEP1 |
| antifungal humoral response | biological process | ADM, APP, LTF, TAC1, CAMP, NPY, IL36RN, CALCA, DEFA4, RARRES2, ANG, FAM3A |
| antifungal innate immune response | biological process | DEFB114, RARRES2 |
| antigen processing and presentation | biological process | IFNG, HLA-DRB1, HLA-DPB1, HLA-B, HLA-DQB1, HLA-A, HLA-E, HLA-DRA, HFE, HLA-DQA1, HLA-G, AZGP1, CD8A, HLA-C, CD74, RAB27A, AP3B1, CTSL, RAB4A, RAB3C, AP3D1, RAB6A, PSMB8, RAB32, RAB8B, PSAP, RAB35, HLA-DQA2, HLA-DMB, CD209, HLA-DOA, RAB3B, HLA-DPA1, CTSS, RAB5B, RAB33A, RAB34, RELB, CTSH |
| antigen processing and presentation of endogenous antigen | biological process | CD74, ATG5 |
| antigen processing and presentation of endogenous peptide antigen via MHC class I | biological process | B2M, ERAP1, ERAP2, TAP1, IDE, TAP2, TAPBP |
| antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent | biological process | ABCB1 |
| antigen processing and presentation of endogenous peptide antigen via MHC class Ib | biological process | HLA-E, MICB, FCGRT, HLA-F |
| antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent | biological process | ABCB1, TAP2 |
| antigen processing and presentation of exogenous antigen | biological process | PSME1, MR1 |
| antigen processing and presentation of exogenous peptide antigen via MHC class I | biological process | IFI30, FCER1G, CLEC4A, MFSD6 |
| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological process | HLA-B, HLA-A, HLA-E, B2M, ITGAV, HLA-G, PSMA3, HLA-C, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SEC22B, PSMD6, PSMD1, SNAP23, PSMD14, PSMD7, CYBB, ITGB5, PSMB6, PSMD10, PSMD8, PSMC5, VAMP8, PSMB4, TAP1, PSME1, PSMB8, PSMD4, PSMC3, PSMA6, TAP2, CYBA, IKBKG, NCF1, VAMP3, PSMD12, TAPBP, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, PSMD5, PSMF1, PSMB3, IKBKB, PSMD3, PSMC1, NCF4, CALR, HLA-F, PSMD13, CD36, PSMB10 |
| antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent | biological process | HLA-B, HLA-A, HLA-E, B2M, HLA-G, HLA-C, LNPEP, HLA-F |
| antigen processing and presentation of exogenous peptide antigen via MHC class Ib | biological process | HLA-F |
| antigen processing and presentation of exogenous peptide antigen via MHC class II | biological process | HLA-DRB1, HLA-DPB1, HLA-DQB1, HLA-DRA, CTSD, HLA-DQA1, KIF3B, DYNC2H1, KIF3A, DYNLL1, DYNC1H1, CENPE, ACTR10, KIF2A, CANX, OSBPL1A, CD74, AP2S1, SEC31A, KLC2, KIF15, CTSV, CTSL, IFI30, SEC24C, SEC13, KIFAP3, SH3GL2, DYNC1I1, AP1G1, CAPZA1, AP1S2, KLC1, DYNC1I2, DCTN3, AP1S1, LGMN, DCTN6, DCTN5, AP2A2, FCGR2B, ARF1, DYNC1LI2, HLA-DQA2, HLA-DMB, SAR1B, AP2M1, HLA-DOA, SPTBN2, RAB7A, KIF5A, KIF2B, AP1S3, CTSF, SEC24B, CLTA, AP2B1, SEC23A, DYNC1LI1, HLA-DPA1, CAPZA2, KIF18A, TRAF6, SEC24D, CLTC, DCTN2, CAPZB, ACTR1A, DCTN4, CTSS, AP1B1, RILP, KIF4A, FCER1G, KIF3C, KIF23, ACTR1B, DYNLL2, AP2A1, KIF26A, KIF4B, AP1M1, SEC24A, KIF11, KIF22 |
| antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent | biological process | ABCB1, B2M |
| antigen processing and presentation of peptide antigen | biological process | CTSS, SLC11A1 |
| antigen processing and presentation of peptide antigen via MHC class I | biological process | ACE, HLA-B, HLA-A, HLA-E, B2M, HFE, HLA-G, PDIA3, AZGP1, HLA-C, ERAP1, CANX, ERAP2, SEC31A, SEC24C, SEC13, TAP1, TAP2, SAR1B, TAPBP, SEC24B, BCAP31, SEC23A, ABCB9, SEC24D, MR1, CALR, SEC24A, HLA-F |
| antigen processing and presentation of peptide antigen via MHC class II | biological process | MARCHF1, MARCHF8 |
| antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological process | HLA-DRB1, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DQA1, HLA-DQA2, HLA-DMB, HLA-DOA, HLA-DPA1 |
| antigen processing and presentation, endogenous lipid antigen via MHC class Ib | biological process | CD1C, CD1E |
| antigen processing and presentation, exogenous lipid antigen via MHC class Ib | biological process | AP3B1, CD1C, AP3D1, CD1E |
| antigen receptor-mediated signaling pathway | biological process | SPG21, BCAR1, SLA2, CD19, SH2B2, LAX1 |
| antimicrobial humoral immune response mediated by antimicrobial peptide | biological process | CCL20, CCL8, REG3A, CXCL11, CCL1, RPS19, RPL30, H2BC21, TSLP, REG1B, CAMP, CCL11, RPL39, DEFB103A, GNLY, CXCL6, NPY, KRT6A, DEFA3, H2BC12, NTS, REG3G, DMBT1, CCL22, DEFB4A, PF4, DEFB1, DEFA5, PGLYRP4, DEFB127, CXCL2, MUC7, PLA2G1B, CXCL1, S100A7, CCL18, RNASE6, RNASE3, CCL19, CALCA, HAMP, DEFA4, BPI, DEFA1, PPBP, CXCL3, CCL28, CXCL14, HRG, ANG, HMGN2, PF4V1, BPIFA1, F2, POMC, CXCL12, FAM3A, CCL17, CCL21, LEAP2, CCL27, CXCL10, HTN3, CXCL5, H2BC10, RNASE7, GALP |
| antimicrobial humoral response | biological process | REG3A, BCL3, CAMP, DEFB103A, GNLY, DEFA3, REG3G, COLEC11, DEFB4A, CTSG, DEFB1, DEFA5, BPIFB1, BPIFA2, PRSS3, ATP7A, S100A8, PI3, S100A7, RNASE6, RNASE3, SLC11A1, PGLYRP2, ITLN1, DEFA4, BPI, DEFA1, BPIFB2, AZU1, PRTN3, BPIFA1, LEAP2, HTN3, RNASE7 |
| antiviral innate immune response | biological process | ATAD3A, RNF135, PHB2, CLPB, AKAP1, ZDHHC11, ZDHHC1 |
| antral ovarian follicle growth | biological process | ESR1, FOXO3, GAS2 |
| aorta development | biological process | MYH10, LTBP1, TAB1, DCTN5, ROBO2, PRDM1, PKD2, SMAD6, LOX, NDST1, LRP2, AP2B1, SUFU, ADAMTS6, PDE2A, PRICKLE1, PLXND1, SNX17, HECTD1, ROBO1 |
| aorta morphogenesis | biological process | FGF8, HES1, ADAMTS9, SEC24B, SIX1, LRP1, PDGFRB, EYA1, NPRL3, JAG1, FOXH1, TBX2 |
| aorta smooth muscle tissue morphogenesis | biological process | COL3A1, PROX1, MYLK |
| aortic valve development | biological process | RBPJ, TBX20 |
| aortic valve morphogenesis | biological process | GATA5, EFNA1, ROCK2, NFATC1, NOTCH1, ROBO2, GATA3, ROCK1, SMAD6, TWIST1, HEY2, TBX20, EMILIN1, ELN, JAG1, SLIT3, SLIT2, ROBO1 |
| apelin receptor signaling pathway | biological process | APLNR |
| apical constriction | biological process | FRMD6, ROCK1, EPB41L5, CCDC88C |
| apical junction assembly | biological process | CTNNA1, WDR1, PKN2, VCL, RHOC, FBF1 |
| apical protein localization | biological process | GOPC, ARF4, SHROOM3, DLG5, JAM3, CELSR1, VANGL2, RDX, NAPA, HCN1, MAL, SHROOM2 |
| apolipoprotein A-I-mediated signaling pathway | biological process | ITGAV, ITGB3, ABCA7 |
| apoptotic cell clearance | biological process | AXL, GAS6, ITGAV, NR1H3, MEGF10, MFGE8, MARCO, HMGB1, ITGB3, TYROBP, TGM2, TXNDC5, TREM2, LRP1, ADGRB1, TREX1, MERTK, RARA, CD36, TYRO3 |
| apoptotic chromosome condensation | biological process | TOP2A, ACIN1, DFFB, ERN2, GPER1 |
| apoptotic DNA fragmentation | biological process | CASP3, DICER1, DNASE2B, ENDOG, HMGB1, KPNA1, H1-0, DFFB, DNASE2, DNASE1L3, DFFA, FOXL2, EXOG |
| apoptotic mitochondrial changes | biological process | BCL2, BAX, AKT1, CDKN2A, MCL1, SLC25A4, NDUFS1, BID, PPIF, IFIT2, HK2, BCL2L1, BIK, PIM2, ATP2A1 |
| apoptotic nuclear changes | biological process | DEDD2, CDK5RAP3, ACVR1C, SHARPIN |
| apoptotic process | biological process | IFNG, IL1B, TP53, BCL2, TNFRSF1A, TNFRSF1B, FAS, CASP1, AHR, BRCA1, CASP4, TNFSF10, CASP6, BAX, BAK1, BCL2L2, BIRC5, CDK1, HMOX1, ERCC2, FGFR2, FGFR3, MAPK3, MAPK1, AKT1, STAT1, CASP3, FASLG, CASP9, E2F1, ATM, CASP8, CDKN2A, CIB1, PEG3, PLAGL1, TLR2, IL1A, NR3C1, GAPDH, APP, GPX1, PAEP, CLU, CSNK2A2, BAG6, PTEN, SEMA3A, BRSK2, BAD, IL2RA, RB1, CYCS, C1QBP, PDCD1, IL17A, RAF1, GJA1, FGF8, MEF2A, MCL1, FOXO1, TP63, 38231, S100A9, PRF1, VDAC1, DYNLL1, MAPK14, TNFRSF25, NOX5, CIDEA, GADD45B, IAPP, HINT1, DAP3, UBE2D3, PPP2R2B, BEX3, TRIM69, SIAH1, SLC5A8, RNF34, IFT57, DDX3X, JAK2, TNFSF15, TNFAIP8, G0S2, GRK5, DDIT3, DAP, CXCR4, STK3, RABEP1, ZNF385B, C3orf38, ZC3H8, CTNNBL1, DPF1, LGALS12, COA8, PAWR, ITCH, RMDN3, PDCD10, DDX47, GHITM, CAAP1, BCL2L12, BCLAF1, OGT, FXR1, PPP2CA, XIAP, ARL6IP1, PDCD2, ZC3H12A, RTL10, ZDHHC16, RNF183, ZNF385A, TRIB3, TRIM39, RTN4, PRELID1, NCKAP1, HIF3A, PTRH2, TNFRSF11B, TNFRSF10C, SIAH2, BCL10, POLR2G, STK4, AIMP2, ESPL1, EMC4, CIAPIN1, TCTN3, TNS4, THOC1, MINDY3, AKTIP, ZMAT3, |
| apoptotic process in bone marrow cell | biological process | BCL2L1 |
| apoptotic process involved in blood vessel morphogenesis | biological process | BAX, BAK1, SPI1, LEF1, LRP5 |
| apoptotic process involved in development | biological process | XKR4, MEGF10, ZPR1, SIX3, XKR6, XKR8 |
| apoptotic process involved in embryonic digit morphogenesis | biological process | BAX, BCL2L11, NOTCH1 |
| apoptotic process involved in heart morphogenesis | biological process | CCN1, NKX2-5, HAND2 |
| apoptotic process involved in luteolysis | biological process | ROBO2, SLIT3, SLIT2 |
| apoptotic process involved in morphogenesis | biological process | CRYAB, PPP2R1B, SCRIB, LEF1, FZD5 |
| apoptotic signaling pathway | biological process | TNF, TNFRSF1B, FAS, BAX, BAK1, CASP3, FASLG, CASP8, TLR4, BAD, SHH, ANXA6, TNFRSF25, DAP3, CD38, DAP, PAWR, LY96, PPARD, TNFSF12, MLLT11, IFI6, FASTK, ITGAM, FADD, DIDO1, TM2D1, CASP2, CFLAR, CD3E, PDCD6, TYROBP, SENP1, IFI27, PTGIS, TICAM2, MAP3K5, DAPK1, BTK, CASP10, P2RX7, IFI27L2, MOAP1, PIDD1, RIPK3, IFI27L1, CASP8AP2, TLR3, CD28, P2RX4, TFPT, DPF2, CD5, CRADD, CAV1, TICAM1 |
| arachidonic acid metabolic process | biological process | MAPK3, CYP1B1, PNPLA8, CYP2J2, PLA2G10, CYP4A11, CYP4F3, PLA2G4C, CYP2C8, FAAH2, CYP4F8, ALOX5, PLA2G4A, ALOXE3, CYP4F12, DAGLB, CYP4F2, ALOX15B, ALOX12B, CYP2D6, CYP2D7, MGLL, DAGLA, FAAH, CYP4F11, EPHX1, CYP2C9 |
| arachidonic acid secretion | biological process | ACE, KISS1R, PNPLA8, PLA2G10, BDKRB2, ANXA1, PLA2G3, PROCA1, PLA2G4A, PLA2G1B, PLA2G12A, NMUR2, NMB, DRD3, PLA2G5, DRD2, PLA2G2D, DRD4, PLA2G12B |
| arginine biosynthetic process | biological process | ASS1, ASL |
| arginine biosynthetic process via ornithine | biological process | ASL |
| arginine catabolic process | biological process | NOS3, NOS2, DDAH1, FAH, DDAH2 |
| arginine catabolic process to glutamate | biological process | OAT |
| arginine catabolic process to proline via ornithine | biological process | OAT |
| arginine metabolic process | biological process | ARG2, DDAH1, ART4, SLC39A8, DDAH2 |
| arginine transmembrane transport | biological process | SLC66A1, SLC7A1 |
| arginine transport | biological process | SLC7A3, SLC66A1, SLC7A1, CLN3, SLC7A2 |
| argininosuccinate metabolic process | biological process | ASS1 |
| arginyl-tRNA aminoacylation | biological process | RARS1, DALRD3, RARS2 |
| aromatic amino acid family catabolic process | biological process | TAT |
| aromatic amino acid family metabolic process | biological process | PAH, FAH, TPH1, GSTZ1, TPH2, TH, TAT, HPD |
| aromatic amino acid transport | biological process | SLC16A10 |
| aromatic compound catabolic process | biological process | PON1, PON2, EPHX2, EPHX1 |
| Arp2/3 complex-mediated actin nucleation | biological process | ARPC1A, ACTR3, ARPC3, IQGAP2, MAGEL2, ARPC5, JMY, ACTR2, ARPC4, ARPC1B, ARPC5L, ACTR3C, ACTR3B |
| arsenate ion transmembrane transport | biological process | SLC34A1 |
| arsenite transport | biological process | GET3 |
| arsonoacetate metabolic process | biological process | N6AMT1 |
| arterial endothelial cell differentiation | biological process | NOTCH1, TMEM100, HEY2, HEY1 |
| arterial endothelial cell fate commitment | biological process | RBPJ |
| artery development | biological process | BMPR2, SHH, GLI3, ACVR2B, SLC2A10, HEY2, ACVRL1, LUZP1 |
| artery morphogenesis | biological process | APOE, VEGFA, APOB, CHD7, HES1, ZMIZ1, LDLR, PRDM1, ANGPTL3, PRRX1, RBPJ, FOXC2, TGFBR1, NOTCH3, WNT11, GJA5, ENG, FOXC1, NRP1, COMP, STRA6, NF1 |
| artery smooth muscle contraction | biological process | EDNRA, CD38, BBS2, MKKS, EDN1, GRIP2, AGT, EDN3 |
| artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure | biological process | CALCA |
| articular cartilage development | biological process | BGN, IFT80 |
| ascending aorta development | biological process | LOX |
| ascending aorta morphogenesis | biological process | HES1, TGFB2, SOX4, HEY2 |
| asparagine biosynthetic process | biological process | ASNSD1, ASNS |
| asparagine catabolic process | biological process | ASPG |
| asparagine catabolic process via L-aspartate | biological process | ASRGL1 |
| asparagine transmembrane transport | biological process | SLC38A5 |
| asparagine transport | biological process | SLC38A7, SLC38A3 |
| asparaginyl-tRNA aminoacylation | biological process | NARS1, NARS2 |
| aspartate biosynthetic process | biological process | GOT1L1, GOT1, GOT2 |
| aspartate catabolic process | biological process | ASPA, GOT1, DDO, GOT2 |
| aspartate metabolic process | biological process | ADSS2, ASS1, GOT1, ADSS1, DDO, GOT2 |
| aspartate transport | biological process | SLC13A3, SLC25A13, PHLPP2, SLC25A18, SLC25A22, LRRC28, LRRC8D, LRRC8C, SLC1A6, LRRC8B, SLC25A12, PHLPP1 |
| assembly of large subunit precursor of preribosome | biological process | RPL24, RSL24D1, EIF6 |
| associative learning | biological process | TAC1, ASIC1, PPT1, GRIN1, LGMN, CRH, GABRA5, RIN1, UCN, BTG2, SNAP25, NPTX2, ACTR2, CLN3, SRF, DRD1, CDK5, CHRNB2, DBH, DRD2, NRGN, SHANK1, EIF4A3, BRSK1, AGT, RELN |
| astral microtubule organization | biological process | EZR, RAB11A, CEP120, DLG1, NUMA1, PDE4DIP, TPPP, CLASP1 |
| astrocyte activation | biological process | IFNGR1, PSEN1, SMO, BACE2, TREM2, FPR2, C1QA, ADORA2A, CNTF, TNF, C5AR1, AGER |
| astrocyte activation involved in immune response | biological process | PSEN1, GRN, LRP1 |
| astrocyte cell migration | biological process | HEXB, CCL3, SCRIB, MMP14, APCDD1, CCL2 |
| astrocyte development | biological process | TLR4, VIM, S100A9, ROR1, CDK6, POU3F2, S100A8, TSPAN2, MT3, EIF2B5, DRD1, LAMC3, DLL1, ROR2, AGER |
| astrocyte differentiation | biological process | LIF, STAT3, NKX2-2, NOTCH1, SOX6, S100B, EIF2B5 |
| astrocyte fate commitment | biological process | SOX9, GCM1 |
| astrocyte-dopaminergic neuron signaling | biological process | FZD1 |
| asymmetric cell division | biological process | ACTR3, PARD3, ACTR2, GOLGA2 |
| asymmetric Golgi ribbon formation | biological process | MYO18A, GOLPH3 |
| asymmetric neuroblast division | biological process | SOX5, ARHGEF2, TEAD3 |
| asymmetric protein localization | biological process | DYNC2H1 |
| asymmetric protein localization involved in cell fate determination | biological process | WNT7A |
| ATF6-mediated unfolded protein response | biological process | HSPA5, DDIT3, HSP90B1, XBP1, MBTPS1, MBTPS2, ATF6B, CALR |
| ATP biosynthetic process | biological process | TGFB1, LDHC, MT-ATP6, MT-ATP8, ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, DMAC2L, ATP5MC3, SLC25A13, ATP5PF, ATP5F1E, DNAJC30, ATP5PD, PRKAG2, PKM, ATP5MC1, ATP5F1D, ATP5MC2, ALDOA, ATP5MG, ATP5MF, ATP5ME, PKLR |
| ATP generation from ADP | biological process | AK9 |
| ATP generation from poly-ADP-D-ribose | biological process | NMNAT1, NUDT5, PARG |
| ATP hydrolysis coupled proton transport | biological process | ATP6V0A2 |
| ATP metabolic process | biological process | MYH7, BAD, HSPA1A, HSPA1B, HSPA8, ATP6V1B1, ATP5F1B, ATP6V1B2, CLPX, AK2, ATP5PF, NADK, CTNS, GUK1, AK4, OLA1, ENPP3, ATP6V1A, NDUFS1, ENPP1, FAM20C, ENTPD5, AK1, ATP5MF, ATP5ME, ATP1A2, AMPD3, ATP1B1, SLC25A25, FIGNL1, MYH3, MYH6, MYH8 |
| ATP synthesis coupled electron transport | biological process | MT-ND4, MT-ND5, NDUFS1, NDUFA7, MT-CO2, MT-ND4L |
| ATP synthesis coupled proton transport | biological process | ATP6V0A2, MT-ATP6, MT-ATP8, ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, ATP5MC3, ATP5PF, ATP5F1E, ATP5PD, ATP5MC1, ATP5F1D, ATP5MC2, ATP5MG, ATP5ME |
| ATP transport | biological process | GJA1, SLC25A4, SLC25A13, SLC25A43, SLC25A48, SLC25A18, SLC25A22, SLC25A41, SLC25A36, SLC25A6, SLC25A5, SLC25A1, SLC25A17, SLC25A24, SLC25A31, SLC25A44, CALHM1, SLC25A16, SLC25A29, SLC25A12, SLC25A25, SLC25A42, SLC25A23, SLC25A21, SLC25A19, SLC25A47 |
| ATP-dependent chromatin remodeling | biological process | MBD2, MTA2, ACTB, SMARCA2, SRCAP, ACTL6A, SMARCA5, HNRNPC, SMARCA4, HDAC2, ERCC6, SMARCE1, ARID1B, INO80B, SMARCB1, SMARCC2, RBBP4, SMARCA1, CHD4, PBRM1, ARID1A, SMARCC1, MBD3, SMARCAD1, GATAD2B, ACTL6B, CHD3, CHD8, INO80, ACTR5 |
| atrial cardiac muscle cell action potential | biological process | GJA1, NUP155, ANK2, SCN5A, GJC1, SCN3B |
| atrial cardiac muscle cell development | biological process | FHL2, NKX2-5 |
| atrial cardiac muscle cell to AV node cell communication | biological process | ANK2 |
| atrial cardiac muscle cell to AV node cell communication by electrical coupling | biological process | GJA5 |
| atrial cardiac muscle tissue development | biological process | TREX1 |
| atrial cardiac muscle tissue morphogenesis | biological process | ENG, PROX1, MYH6 |
| atrial septum development | biological process | MDM2, MDM4, ANK2, TBX5, NPHP3, WNT11, GJA5, DAND5 |
| atrial septum morphogenesis | biological process | GATA4, CCN1, ISL1, SMO, TGFB2, TBX5, HEY2, TBX20, GJA5, NKX2-5, ZFPM1 |
| atrial septum primum morphogenesis | biological process | GATA4, ACVR1, NSD2, TGFB2, SOX4 |
| atrial septum secundum morphogenesis | biological process | GATA4, NSD2 |
| atrial ventricular junction remodeling | biological process | GJA1, GJA5 |
| atrioventricular bundle cell differentiation | biological process | TBX3 |
| atrioventricular canal development | biological process | PTPN11, SMAD4, HAS2, RBPJ, FOXN4, TBX2 |
| atrioventricular canal morphogenesis | biological process | ENG |
| atrioventricular node cell development | biological process | NKX2-5, MAML1 |
| atrioventricular node cell fate commitment | biological process | NKX2-5 |
| atrioventricular node development | biological process | NOTCH1, NKX2-5, MAML1 |
| atrioventricular valve development | biological process | HEY2 |
| atrioventricular valve formation | biological process | OLFM1, SMAD4, HEY1 |
| atrioventricular valve morphogenesis | biological process | MDM2, CCN1, ACVR1, MDM4, NOTCH1, TGFB2, TBX5, TGFBR2, BMP2, SLIT3, ZFPM1 |
| attachment of GPI anchor to protein | biological process | PLAUR, PIGS, PGAP1, GPAA1, PIGK, PIGT, PIGU |
| attachment of mitotic spindle microtubules to kinetochore | biological process | CENPE, MIS12, NDC80, SEH1L, MAD1L1, CENPC, NUF2 |
| attachment of spindle microtubules to kinetochore | biological process | AURKC, ABRAXAS2, BUB3, NDC80, ZNF207, SGO1, ABRAXAS1, AURKB |
| auditory behavior | biological process | NEUROG1, SLC1A3, SLITRK6, TIFAB, DRD2 |
| auditory receptor cell development | biological process | FGFR1, SLC4A7, LRTOMT, TMC1, PDZD7 |
| auditory receptor cell fate commitment | biological process | NOTCH1, RBPJ, JAG2 |
| auditory receptor cell morphogenesis | biological process | SCRIB, SLITRK6, SEC24B |
| auditory receptor cell stereocilium organization | biological process | SOD1, STRC, SLC9A3R1, REST, SCRIB, SEC24B, TRIOBP, TPRN, LHFPL5, MYO7A, WHRN, PDZD7, RIPOR2 |
| autocrine signaling | biological process | SERPINB3, CX3CR1, S100A8, HILPDA, FZD1 |
| autonomic nervous system development | biological process | PHOX2B, PHOX2A, GBX2, PRLH |
| autophagic cell death | biological process | SH3GLB1, CTSV, TP53INP1, CDKN2D, BNIP3, CDKN1B, LAMP1 |
| autophagosome assembly | biological process | STX12, RB1CC1, MAP1LC3A, RAB1A, TP53INP1, EMC6, ATG12, BAG3, UBXN2A, PIK3C3, ULK2, RUFY4, ATG5, ULK1, PSEN1, ATG16L2, RAB23, WDR45, RAB7A, ELAPOR1, ATG2B, NSFL1C, SYNPO2, WIPI2, BECN1, WDR45B, UBXN2B, ATG9A, GABARAPL1, ATG3, GABARAP, IRGM, GABARAPL2, WIPI1, MAP1LC3B, STING1, RAB33B, TRAPPC8, ATG101, TCIRG1, ATG2A, PACS2, RAB1B, TMEM41B, AMBRA1, ATG13, ATG9B, VMP1, ATG16L1, MAP1LC3C |
| autophagosome maturation | biological process | TSG101, MAP1LC3A, VTI1B, SNX14, SNAPIN, VAMP8, VPS33B, VIPAS39, SNAP29, LAMP2, STX17, LIX1L, MFSD8, WIPI2, VAMP7, GABARAPL1, RUBCNL, GABARAP, UVRAG, GABARAPL2, MAP1LC3B, CLN3, LIX1, VPS16, VPS33A, TECPR1, MCOLN1, CHMP3, MAP1LC3C |
| autophagosome membrane docking | biological process | VAMP8, SNAP29, STX17 |
| autophagosome organization | biological process | ATP13A2, PIK3C2B |
| autophagosome-endosome fusion | biological process | RUBCNL |
| autophagosome-lysosome fusion | biological process | ATP13A2, RUBCNL, CLN3 |
| autophagy | biological process | CTSD, PARK7, FOXO1, S100A9, VPS41, FUNDC1, OPTN, TRIM17, LGALS8, GPR137B, DAP, RB1CC1, USP13, TMEM74, MAP1LC3A, ANXA7, VPS18, RAB1A, C9orf72, SH3GLB1, XBP1, TP53INP1, ATG10, TMBIM6, FNBP1L, ATG4A, TMEM208, VAMP8, RNF41, RETREG1, EVA1A, C19orf12, PRKN, SUPT20H, TMEM59, TMEM39A, TECPR2, ATG12, PHF23, CHMP4B, ATP13A2, PIK3C3, SNAP29, LAMP2, STX17, LIX1L, SIRT2, ULK2, RUFY4, ATG5, WDR41, PTPN22, ULK1, HMGB1, ARSB, PSEN1, SQSTM1, ULK3, ATG16L2, GPR137, PINK1, WDR45, RAB7A, SRPX, RAB39A, ELAPOR1, SBF2, ATG2B, EI24, ITGB4, TOLLIP, WIPI2, MFN2, BECN1, WDR45B, MAP1S, DRAM1, ATG4B, ABL1, IFI16, DRAM2, ATG9A, NRBF2, GABARAPL1, RUBCNL, ATG3, GABARAP, CLTC, CALCOCO2, ACBD5, WDFY3, RUBCN, UVRAG, IRGM, NPC1, S100A8, PRKAA2, GABARAPL2, WIPI1, SMCR8, GRAMD1A, RNF185, MAP1LC3B, VPS51, STING1, LIX1, RMC1, ATG4C, RAB33B, HDAC6, STBD1, DRD3, IRF8, TRAPPC4, RGS19, VTI1A, VPS16, USP10, TBC1D5, HDAC10, ATG101, TIGAR, DEPP1, RAB8A, TCIRG1, CD84, TM9SF1, TFEB, VPS33A, WDR24, DRD2, CLEC16A, ATG2A, TECPR1, TBC1D25, LRSAM1, WDFY4, ATG4D, |
| autophagy of nucleus | biological process | ATG12, ATG5, WDR45, ATG2B, WIPI2, WDR45B, ATG3, WIPI1, ATG2A, ATG13 |
| autophagy of peroxisome | biological process | RB1CC1, PIK3C3, ACBD5, PIK3R4, TRAPPC8 |
| AV node cell action potential | biological process | CACNA1G, SCN4B, SCN5A, SCN10A |
| AV node cell to bundle of His cell communication | biological process | CXADR, GJA5, SCN5A |
| AV node cell to bundle of His cell communication by electrical coupling | biological process | GJA5, GJC1 |
| AV node cell to bundle of His cell signaling | biological process | CACNA1G |
| AV node cell-bundle of His cell adhesion involved in cell communication | biological process | CXADR |
| axial mesoderm development | biological process | RPL38, EPB41L5, POGLUT1, FOXH1 |
| axial mesoderm formation | biological process | EPHA2 |
| axial mesoderm morphogenesis | biological process | EPB41L5 |
| axial mesodermal cell fate specification | biological process | NODAL |
| axis elongation | biological process | PTK7 |
| axis elongation involved in somitogenesis | biological process | WNT3A, LRP6, MED12 |
| axis specification | biological process | WNT6 |
| axo-dendritic transport | biological process | APP, HSPA8, SPG11, APBA1, KLC3 |
| axon choice point recognition | biological process | EFNB3, GAP43 |
| axon development | biological process | CAMSAP2, MARK2, NEFH, TRIM32, VASH2, ZPR1, SVBP, TSPAN2, L1CAM, SPRY3, NEFL |
| axon ensheathment | biological process | NRG1, CLDN11, PPARD, PRX, MBP, QKI |
| axon extension | biological process | SEMA7A, ITGB1, NDN, AUTS2, C9orf72, DVL1, PPP3CB, ULK2, SPG11, ULK1, RAPH1, CYFIP1, VCL, DCLK1, USP9X, POU4F2, SLC9A6, CDK5, MAP1B, LHX2, SEMA5A |
| axon extension involved in axon guidance | biological process | SEMA3A, SEMA3F, SLIT1, NRP2, ALCAM, NRP1, SLIT3, SLIT2 |
| axon guidance | biological process | ANOS1, BDNF, MAPK3, MAPK1, BMP7, SEMA3A, NCAM1, EZR, SOS1, TUBB3, SHH, FLRT3, NTRK1, KIF26B, SEMA3E, GLI3, KIF5B, RYK, SIAH1, CNTN4, SEMA6D, LRTM1, MYH10, CXCR4, DPYSL2, PALLD, PLA2G10, EXT1, FEZ2, NPTN, PIK3R1, SHC1, SEMA3F, SMAD4, SPTBN5, LGI1, VASP, DVL1, PTPRA, EFNA1, EPHB2, PTK2, NEXN, GRB10, SEMA4C, ARHGAP35, MATN2, SPTBN1, ROBO4, SEMA3G, SEMA4G, SLIT1, NOTCH1, WNT3A, VLDLR, SEMA4D, APBB2, ROBO2, IGSF9, FLRT2, NTN1, GATA3, CNTN2, PRKCQ, DRAXIN, FEZ1, IRS2, EFNA5, EPHB1, SCN1B, NRCAM, NTN4, NRXN3, GRB7, MYPN, USP33, CYFIP2, EPHA6, GAB2, SPTBN2, DCC, KIF5A, CHL1, NRP2, UNC5C, CDK5R1, DPYSL5, TENM2, GRB2, GAB1, UNC5D, EVL, MAPK7, CYFIP1, EFNA2, NFASC, ALCAM, ENAH, FRS2, DSCAM, TRIO, ETV1, EPHA4, OR10A4, SEMA6A, PLXNA4, KLF7, SPTB, EPHA1, SPTAN1, PDLIM7, NOTCH3, OPHN1, DLX5, EFNB1, POU4F2, NECTIN1, PTPRO, NRTN, RPS6KA5, RET, EPHA2, RAP1GAP, EFNB2, SEMA3B, EPHA7, SEMA3C, SEMA6C, PIK3CD, DOK2, PSPN, GBX2, DAG1, EFNB3, VSTM2L, ARX, GFRA3, NGFR, EPHA3, EPHA8, GPC1, GDF7, LMX1A, NR4A3, DOK1, SEMA6B, NRP1, PLXNA3 |
| axon midline choice point recognition | biological process | APP, ROBO2, FOXG1, ROBO1, ROBO3 |
| axon regeneration | biological process | BCL2, MTR, JAK2, ISL1, CTNNA1, JAM3, DHFR, NREP, DAG1, RTN4RL2, MAG, RTN4RL1, FOLR1, GAP43 |
| axon target recognition | biological process | FOXB1, UCHL1 |
| axonal fasciculation | biological process | SEMA3A, CNTN4, NDN, RTN4, NCAM2, EPHB2, ARHGAP35, CNTN2, NRCAM, CRTAC1, CNR1, CDK5R1, TNFRSF21, NRP1, EPHB3, AMIGO1, CELSR3, SEMA5A |
| axonal transport | biological process | AGBL4 |
| axonal transport of mitochondrion | biological process | HIF1A, OPA1, TRAK1, SPAST, NEFL, UCHL1 |
| axonemal central apparatus assembly | biological process | HYDIN |
| axonemal dynein complex assembly | biological process | CCDC103, SPAG1, DNAAF1, CCDC65, DNAAF3, DNAAF2, DRC1, CCDC40 |
| axonemal microtubule depolymerization | biological process | KIF19 |
| axoneme assembly | biological process | SPAG16, OFD1, JHY, FOXJ1, TOGARAM1, TTC26, TTLL1, RSPH9, RP1, DCX, RSPH6A, CFAP206, CFAP46, GAS8, LRGUK, CCDC40, TTLL3, RP1L1, CFAP74, CC2D2A |
| axonogenesis | biological process | BCL2, FGFR2, GSK3B, APP, BRSK2, PTPN11, DSCAML1, SHTN1, RYK, CNTN4, NUMBL, MYH10, ISL1, NDN, BAIAP2, TNN, ANK3, ALS2, RTN4R, NEFH, NUMB, PITPNA, DVL1, ATL1, CTNNA2, CCKAR, TAOK2, SLIT1, S100A6, STMN1, NOTCH1, WNT3A, PICALM, NTNG1, NTN1, SLITRK4, ULK2, BCL11B, SLITRK5, NRCAM, ULK1, PARD3, SLITRK1, DCC, LLGL1, FLOT1, CNP, MAP2, DOCK7, SLITRK6, AFG3L2, MAP1S, RNF165, ATP8A2, NTNG2, TOP2B, DCLK1, PARD6B, KLF7, S100B, POU4F1, NKX2-8, DLX5, POU4F2, PLPPR4, VAX2, ADGRB1, PAK3, SLITRK3, CCK, CDK5, PTPRZ1, RAB8A, SLITRK2, APBB1, DRD2, AMIGO1, BRSK1, SPTBN4, WNT7A, MAP1B, TRIM46, SPAST, UCHL1 |
| axonogenesis involved in innervation | biological process | SEMA3A, NTRK1, NPTX1, NRP1, COL25A1 |
| azole transmembrane transport | biological process | SLC28A2, SLC28A1 |
| B cell activation | biological process | IL4, CASP8, CD79A, HSPD1, MALT1, HDAC4, BANK1, BST2, HDAC9, RASGRP1, LAT2, CXCR5, CD86, ZAP70, PHB2, PRKCB, SKAP2, IGBP1, MS4A1, BTK, PIK3CD, CD22, CHRNB2, CHRNA4, HDAC5, ICOSLG, CD40, LAX1 |
| B cell activation involved in immune response | biological process | GPR183 |
| B cell adhesion | biological process | CD209 |
| B cell affinity maturation | biological process | BTK |
| B cell apoptotic process | biological process | BAX, BAK1, BCL10, BCL2L11, TRAF3IP2, TNFRSF21, PKN1, CRKL |
| B cell chemotaxis | biological process | GAS6, CH25H, HSD3B7, PIK3CD |
| B cell costimulation | biological process | IL4, TNFSF13B, TNFRSF13C |
| B cell cytokine production | biological process | HSPD1 |
| B cell differentiation | biological process | IL4, BCL2, RAG1, IL11, IL10, IFNA1, ITGB1, CD79A, ITGA4, NTRK1, MSH2, HDAC4, CEBPG, FZD9, VCAM1, PIK3R1, CD79B, BCL6, DNAJB9, LYL1, RABL3, HDAC9, PTPN2, IFNA8, DCLRE1C, DCAF1, SP3, NKX2-3, IFNA10, PTPRC, GON4L, EP300, CDH17, GPS2, TPD52, RBPJ, MS4A1, CR2, ADGRG3, NFAM1, KLF6, IFNA2, IFNA14, ONECUT1, TCIRG1, ZBTB7A, HHEX, HDAC5, JAK3, IFNW1, CARD11, PLCG2, CLCF1, RAG2, NHEJ1, ZBTB1 |
| B cell homeostasis | biological process | BCL2, BAX, BAK1, CASP3, SOS1, BCL2L11, MEF2C, RC3H2, DOCK11, TNFSF13B, RC3H1, LYN, NCKAP1L, TNFRSF13C, PKN1, SPNS2, TNFRSF13B, DOCK10 |
| B cell homeostatic proliferation | biological process | BAX, RAG2 |
| B cell lineage commitment | biological process | BCL2, PRKDC, TP53, RAG2 |
| B cell mediated immunity | biological process | FAS, MSH2, SLA2, CD19 |
| B cell negative selection | biological process | BAX, BAK1 |
| B cell proliferation | biological process | BCL2, IL10, IFNA1, CD79A, HSPD1, IFNA8, RASGRP1, CTPS1, ATAD5, MEF2C, IFNA10, PTPRC, ABL1, IL7R, PRKCD, MS4A1, CR2, LEF1, IFNA2, IFNA14, IFNW1, CD40, CARD11 |
| B cell proliferation involved in immune response | biological process | TLR4, ABL1, CD19, PLCL2 |
| B cell receptor apoptotic signaling pathway | biological process | BAX |
| B cell receptor signaling pathway | biological process | BCL2, MAPK1, CD79A, CD38, CD79B, VAV3, PLEKHA1, MNDA, SYK, PTPN6, LAT2, CTLA4, BCAR1, ITK, MEF2C, KLHL6, NFATC2, PTPRC, TEC, PRKCB, IGLL5, RFTN1, ABL1, LYN, MS4A1, BTK, IGLL1, NCKAP1L, LIME1, PIK3CD, LCK, CD19, PLCG2, SH2B2, BLK |
| B-1 B cell differentiation | biological process | MALT1, CD19 |
| B-1 B cell homeostasis | biological process | HIF1A, ABL1 |
| B-1 B cell lineage commitment | biological process | SLAMF8 |
| B-1a B cell differentiation | biological process | CMTM7, PLCL2 |
| baculum development | biological process | ESR1 |
| barbed-end actin filament capping | biological process | TWF1, CAPZA3, SCIN, CAPZA1, EPS8, ADD3, ADD2, CAPZA2, RDX, CAPZB, TRIOBP, CAPG, ADD1, TWF2, AVIL, VIL1 |
| barbed-end actin filament uncapping | biological process | CARMIL1 |
| basal dendrite arborization | biological process | TAOK2, NRP1 |
| basal dendrite development | biological process | NRP1 |
| basal dendrite morphogenesis | biological process | TAOK2 |
| basal protein localization | biological process | ERBIN |
| base conversion or substitution editing | biological process | ADARB1, ADAR, APOBEC3F, APOBEC3G |
| base-excision repair | biological process | TP53, OGG1, XRCC1, XPA, POLQ, PARP2, APEX1, PRMT6, MPG, USP47, NEIL1, RPA2, FEN1, HUWE1, ERCC6, RPA1, APEX2, TDG, NEIL2, HMGA2, NTHL1, MUTYH, RPA3, SMUG1, LIG1, SIRT6, POLB, NEIL3, POLL, UNG, DNTT |
| base-excision repair, AP site formation | biological process | TDG, NTHL1 |
| base-excision repair, AP site formation via deaminated base removal | biological process | UNG |
| base-excision repair, base-free sugar-phosphate removal | biological process | APEX1, POLB |
| base-excision repair, DNA ligation | biological process | XRCC1, LIG3, POLB |
| base-excision repair, gap-filling | biological process | POLG, POLE, POLB, POLL, POLD1 |
| basement membrane assembly | biological process | RAMP2, NTN4, MEGF9, LAMB1, PLOD3, LAMB3, PXDN |
| basement membrane disassembly | biological process | HPN, CTSS |
| basement membrane organization | biological process | SPINT2, COL4A1, FERMT1, FLRT2, CAV2, NID2, DAG1, GAS2, MMP11, RIC8A, CAV1 |
| basic amino acid transmembrane transport | biological process | SLC7A6, SLC66A1, SLC3A1, SLC7A1, SLC7A7, SLC7A4 |
| basic amino acid transport | biological process | SLC3A1 |
| basophil activation involved in immune response | biological process | KARS1, ENPP3 |
| basophil chemotaxis | biological process | VEGFA |
| basophil degranulation | biological process | PI4K2A |
| basophil differentiation | biological process | GATA1 |
| basophil homeostasis | biological process | MPL |
| behavior | biological process | TRMT1L, HTR2C, HTR1B, OPRL1, OPRK1, HTR2B |
| behavioral defense response | biological process | EP300 |
| behavioral fear response | biological process | BCL2, ESR2, VDAC1, ASIC4, ASIC1, ALS2, MDK, DEAF1, GABRA5, MORC1, EIF4E, ATP1A2, MECP2, DPP4, HTR2C, DRD1, BRINP1, MAPK8IP2, GRIK2, GRM7, DRD4, FBXL20, PENK |
| behavioral response to cocaine | biological process | PPP1R1B, HOMER2, FADD, ABAT, HOMER1, DRD3, DRD1, CDK5, DRD2, SDK1, DRD4 |
| behavioral response to ethanol | biological process | HDAC2, CRHBP, EPS8, DBH, DRD2, DRD4, UNC79 |
| behavioral response to formalin induced pain | biological process | NTRK1, P2RX3 |
| behavioral response to nicotine | biological process | CHRNA5, CHRNB1, CHRNA3, CHRNB2, CHRNA4, PPARA, CHRNB4 |
| behavioral response to nutrient | biological process | SLC16A1 |
| behavioral response to pain | biological process | CAPN2, THBS1, LPAR5, THBS4, P2RX4, P2RX3, VWA1, P2RX2, TRPV1 |
| behavioral response to starvation | biological process | GALP |
| benzene metabolic process | biological process | CYP2E1 |
| benzoate metabolic process | biological process | ACSM1 |
| benzoyl-CoA metabolic process | biological process | GLYAT |
| Bergmann glial cell differentiation | biological process | MAPK3, MAPK1, VIM, PTPN11, SHH, TTC21B, ABL1, MAP2K1 |
| beta selection | biological process | SYK, ZAP70 |
| beta-alanine biosynthetic process | biological process | UPB1, DPYD |
| beta-alanine biosynthetic process via 3-ureidopropionate | biological process | UPB1 |
| beta-alanine metabolic process | biological process | DPYS, AASDH, UPB1 |
| beta-amyloid metabolic process | biological process | ACE, APEH, IDE, PSEN1, BACE2, NAT8, MME, PSEN2, BACE1, UNC13A, MGAT3 |
| beta-carotene metabolic process | biological process | BCO1 |
| beta-catenin destruction complex assembly | biological process | GSK3B, CSNK1A1, AXIN1, APC, AMER1 |
| beta-catenin destruction complex disassembly | biological process | GSK3B, CTNNB1, CSNK1A1, DVL1, FZD2, WNT3A, WNT8B, AXIN1, LRP6, APC, DVL2, AMER1, FZD5, DVL3, FRAT2, FZD1, CAV1 |
| beta-catenin-TCF complex assembly | biological process | TERT, CTNNB1, PYGO2, TCF7L2, MYC, HIST1H4A, TCF7, TLE1, ASH2L, SMARCA4, TCF7L1, BCL9, RBBP5, CREBBP, KMT2D, MEN1, CDC73, TLE4, EP300, KAT5, RUVBL1, BCL9L, PYGO1, LEF1, TLE2, AXIN2, LEO1, TLE3 |
| bicarbonate transport | biological process | CFTR, SLC26A8, CA2, SLC26A4, SLC26A3, SLC4A7, CA5A, CA9, SLC26A9, CA13, SLC4A4, SLC26A5, SLC26A7, HBB, SLC39A8, CA14, SLC26A2, CYB5R4, CYB5R2, CA12, SLC4A2, SLC4A11, AQP1, CA3, CA7, SLC4A8, HBA1, SLC26A1, SLC4A1, CA4, SLC4A3, SLC26A10, SLC26A6, RHAG, CA1, SLC4A10, SLC4A9 |
| bicellular tight junction assembly | biological process | ITGB1, CLDN14, CLDN6, CLDN2, MARVELD3, CLDN9, CLDN15, CLDN5, ARL2, RAMP2, MPP7, CLDN16, CLDN18, POF1B, PARD3, CLDN23, STRN, APC, DLG1, ECT2, F11R, CLDN17, PARD6A, PDCD6IP, PARD6B, CLDN10, ESAM, WNT11, TBCD, SRF, CDH5, CLDN1, PECAM1, CLDN7, CLDN4, ACTN4, MICALL2, CRB3, PARD6G, FRMPD2, AFDN, CLDN8 |
| bile acid and bile salt transport | biological process | ALB, NCOA2, SLCO1B3, ABCC3, SLC27A5, SLC10A6, SLCO1A2, NR1H4, NCOA1, SLC10A3, SLCO2B1, CEACAM1, STARD5, SLC51B, ATP8B1, ABCB11, SLC10A7, SLCO1C1, AKR1C1, AKR1C4, SLC10A2 |
| bile acid biosynthetic process | biological process | HSD17B4, SCP2, OSBPL1A, AMACR, STAR, BAAT, SLC27A5, OSBPL2, CH25H, HSD3B7, CYP8B1, OSBPL9, OSBPL6, OSBPL7, SLC27A2, OSBP, OSBPL3, CYP46A1, ABCB11, ACOX2, AKR1D1, AKR1C4 |
| bile acid catabolic process | biological process | SULT2A1, AKR1D1 |
| bile acid conjugation | biological process | BAAT |
| bile acid metabolic process | biological process | NR5A2, LEP, ARV1, SCP2, AMACR, ACAA1, BAAT, SLC27A5, NR1H4, GBA2, NPC1, ATP8B1, AKR1C1 |
| bile acid secretion | biological process | SLC9A3R1, STARD10, ABCB4, SLC51B |
| bile acid signaling pathway | biological process | VDR, NR1H4 |
| bilirubin conjugation | biological process | UGT1A4 |
| binding of sperm to zona pellucida | biological process | ACR, HSPA1L, SPAM1, CRISP1, ZPBP, SPA17, CCT5, CCT4, CCT7, ATP8B3, CCT2, TCP1, POMZP3, CCT3, ALDOA, CCT8, PCSK4, ADAM2, ZPBP2, B4GALT1, ADAM30, OVGP1, ZAN, FETUB, ZP3, VDAC2, UBAP2L, TEX101 |
| biological_process | biological process | MSMB, DMRT2, APOA1BP, INSL6, TAF7L, DPF3, TSPYL1, SLC6A8, YLPM1, DNAH5, PLCH2, VPS41, LRBA, REEP5, CFAP70, LHFPL2, H2AZ2, UBR7, TMEM116, C6orf62, MRPL47, ZMYM2, CALU, MFSD11, TMEM50B, MRPS22, COTL1, HMGN3, QRICH1, TTC27, DAW1, FAM184A, SCFD2, TMEM106C, GHITM, C11orf1, EMC7, ASNSD1, EMC3, MPC1, LRRFIP2, FAU, ATP5MPL, LYPLAL1, CWF19L1, DLEU7, AKAP14, CPNE8, C19orf18, DCUN1D4, TM6SF1, NYX, MRPL46, SMCO4, PXMP4, ZFAND5, RBM10, KRT24, NOM1, MINDY1, FNDC5, CFAP36, BRD9, TAS2R9, CDV3, TSPAN3, ZNF77, CCDC6, GRIPAP1, DHRS7B, POMZP3, KRT73, LRRC34, TRIM58, KIAA1191, MRPS24, H2AC12, SULT4A1, GGTLC1, MKRN2, C21orf62, DIP2B, WASHC3, NEMP1, SFT2D2, RWDD2B, GGTLC2, MIDN, TPRG1L, MBLAC2, SLC22A15, SH3TC1, IMMP1L, POPDC3, FANCF, ETNK2, SIPA1L2, EPB41L3, SMIM24, SDC2, SLC35D2, ZNF114, KIF12, CDCA3, HDHD2, PLEKHA3, APMAP, LRIT1, ARPP21, MATN2, TSPAN9, METTL18, MAGEA6, SMIM11A, GNL2, C9orf64, INO80C, LRRTM1, LENG1, DCUN1D5, H2AJ, CHCHD7, AKAP7, ZNF107, ZNF223, SBNO1, CDRT1, ZBTB11, EVA1C, TMEM52B, EDC4, IGFL2, VMO1, TMPRSS11B, N |
| biomineral tissue development | biological process | BGLAP, ECM1, SLC20A1, SPP1, ASPN, ENPP1, PHEX, CNNM4, FAM20C, ODAM, STATH, AMBN, ITGB1BP1, SRGN, CEMP1, FAM20A, FAM83H, TUFT1, OTOP1, ALPL, TFIP11, WDR72, KLK4, HTN3 |
| biosynthetic process | biological process | NMNAT1, GART, FDFT1, GOT1L1, OLAH, EIF2B3, NMNAT3, APMAP, PCYT1B, GPT, MTFMT, FASN, PCYT2, SPTLC3, GOT1, GPT2, SPTLC1, GCAT, ALDH1L1, KYAT1, SPTLC2, TAT, AADAT, ACCS, FPGS, COASY, GMPPA, GMPPB, GOT2, ALAS1, NMNAT2, PCYT1A, ALDH1L2 |
| biotin import across plasma membrane | biological process | SLC27A1, SLC5A6 |
| biotin metabolic process | biological process | PCCA, MCCC1, PC, BTD, MCCC2, PCCB, SLC5A6, HLCS |
| biotin transport | biological process | SLC27A1, SLC5A6, ABCG2 |
| biphenyl metabolic process | biological process | SRD5A2, CYP17A1, STAR, CYP4B1 |
| blastocyst development | biological process | XAB2, HORMAD1, ETV2, NASP, CAPN2, EOMES, SPIC, PSMC3, MED21, THOC2, PSMC4, EMG1, TGFBR1, CDX2, DAD1, NEK2 |
| blastocyst formation | biological process | SKIL, ACTL6A, RTN4, KDM4C, TM4SF1, CCNB1IP1, MFNG, SF3B6, MFN2, WDR74, RPL7L1, GABPA, PTPN18, FURIN, RRP7A, ZP3 |
| blastocyst growth | biological process | NBN, RTF1, CTR9, ZNF830 |
| blastocyst hatching | biological process | SLC35E2B, RBBP8, BCOR, PHF6, CMTM3, LPAR6, HCFC1, NDUFA2, PEMT, STMN3, CTR9, NECAB1, CCDC62, PPP4R4, SMIM14, ARHGDIG, C6orf141, PLPP4, SLC25A34, ASF1B, Grn, HS3ST6 |
| bleb assembly | biological process | PMP22, ANO6, EMP1, EMP2, ROCK1, LPAR1, P2RX7, LPAR3, MYLK |
| blood circulation | biological process | ADM, STAT1, MTHFR, F5, CHD7, E2F4, OLR1, BDKRB2, HTR7, GUCY1B1, COL4A3, GUCY1A1, TBC1D8, PLN, IMMP2L, CYB5R3, C3AR1, UTS2R, TBX20, NFE2, MYOF, SERPING1, ELN, ACVRL1, HOXB2, MEOX2, HCN4, EPO, ADORA2A, CXCL12, EDN3, FLI1, CXCL10 |
| blood coagulation | biological process | F10, SERPINC1, IFNA1, VWF, TFPI2, GAS6, SERPINA1, C3, F5, F3, PLAUR, SERPINA5, PLAU, PLAT, F2R, GATA4, CDC42, SHH, ANXA5, ZFPM2, JAK2, F2RL3, PAFAH2, GP1BB, PRKAR2A, GATA5, SH2B3, RAD51C, TFPI, RAB27A, HDAC2, AP3B1, MPIG6B, PROC, PRKACB, CAPZA1, ANO6, GP6, THBD, F7, CD59, C4BPB, IFNA8, HBG2, FGG, RAB5A, LMAN1, VPS45, MAFG, PROS1, GP9, GATA3, HPS4, HMG20B, F12, DTNBP1, P2RY12, MAFF, IFNA10, HBD, FGB, ITGA2, HBB, HGFAC, DOCK11, DOCK9, AKAP1, ITGB3, COL1A2, GNA12, MFN2, RAC1, ITPK1, DOCK8, CAPZA2, GNAQ, AK3, RCOR1, LYN, PRKACG, DOCK1, CARMIL1, PAPSS2, IRF2, GATA2, CAPZB, DOCK6, RAD51B, AKAP10, F8, P2RX7, P2RX6, MAFK, IRF1, HNF4A, P2RY1, MMRN1, NFE2, SCUBE1, EHD2, F2RL2, PLG, FCER1G, PRKAR2B, IFNA2, IFNA14, FGA, WAS, EHD3, HRG, SERPING1, PRKAR1B, CBX5, CYP4F2, P2RX4, SERPINA10, GP1BA, PRTN3, COMP, H3C1, PABPC4, ADAMTS13, MICAL1, P2RX5, TSPAN32, PROCR, F2, P2RX3, SLC4A1, ADORA2A, P2RX2, PROZ, ZFPM1, PHF21A, SH2B2, H3-3A, VKORC1, LNPK, CYP4F11, ANXA8, GATA1, CD36, H3C13, HPS5 |
| blood coagulation, common pathway | biological process | FGA |
| blood coagulation, extrinsic pathway | biological process | F10, F3, TFPI, F7 |
| blood coagulation, fibrin clot formation | biological process | FGG, FBLN1, FGB, FGA |
| blood coagulation, intrinsic pathway | biological process | F10, VWF, A2M, C1QBP, GP1BB, PRCP, GP9, F12, F8, SERPING1, GP1BA, F2, APOH |
| blood vessel development | biological process | AHR, HIF1A, MDM2, ITGAV, BMP4, ESX1, PROP1, FOXO1, CHD7, ALDH1A2, PKD1, TCF7L2, ANTXR1, MIB1, SPHK2, TDGF1, FZD4, RAPGEF2, FLVCR1, TIE1, SOX18, PTK2, COL3A1, MEF2C, FOXS1, PSEN1, RAPGEF1, MAP3K3, COL1A2, LOX, CFC1B, FOXC2, ATP7A, HEY2, TBX3, GJA5, PDGFRB, CEACAM1, COL5A1, EPHA2, TGFBR2, CDX2, EGFL7, GJA4, APLNR, FOXF1, CCM2, DHCR7, FOXC1, TREX1, STRA6, CRKL, CDX4 |
| blood vessel endothelial cell differentiation | biological process | CCM2 |
| blood vessel endothelial cell fate specification | biological process | RBPJ |
| blood vessel endothelial cell migration | biological process | GPX1, SOX18, SCARB1, AMOT, EMP2, APOA1, CDH5, MYH9, PTK2B |
| blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | BMP4, ITGB1BP1, NRARP, EPHA2, ACVRL1, BMPER, SEMA5A |
| blood vessel lumenization | biological process | RBPJ |
| blood vessel maturation | biological process | MMP2, DDIT3, LYL1, S1PR1, ANKRD17, CDH5, ACVRL1, RECK |
| blood vessel morphogenesis | biological process | HIF1A, FLT1, FGFR1, GJA1, NR2F2, SOS1, CYP1B1, ETV2, RASA1, COL4A1, FLT4, SYK, FOXN1, AMOT, SERPINF2, NEDD4, LOX, ANGPT2, AIMP1, MEIS1, EPHA2, EFNB2, EDN1, ACVRL1, GDF2, FGF10 |
| blood vessel remodeling | biological process | ACE, LIF, NOS3, BAX, BAK1, AXL, MDM2, BMPR2, FGF8, HOXA3, ACVR2B, MEF2C, ATG5, BGN, RBPJ, FOXC2, CRB1, ATP7A, EPAS1, TGM2, RSPO3, SEMA3C, ACVRL1, FOXC1, DBH, JAG1, AGT, FGF10 |
| blue light signaling pathway | biological process | CRY1, CRY2 |
| BMP signaling pathway | biological process | USP9Y, MAPK3, NODAL, BMP7, TGFBR3, HFE, GDF9, BMP15, BMP4, BMPR2, FGF8, UBE2D3, SMAD4, CER1, ACVR1, RGMA, EGR1, BMPR1A, ZFYVE16, FSTL1, ACVR2B, HJV, SKI, MSX1, PDCD4, SLC39A5, MEGF8, GREM2, SMPD3, SMAD6, BMP5, TGFB2, SOSTDC1, RGMB, LEFTY1, TWSG1, SLC33A1, UBE2D1, USP9X, TMEM100, LEF1, BMP6, ACVR2A, ZCCHC12, USP15, HIVEP1, DLX5, RUNX2, MSX2, BMP2, ZNF8, SMURF2, GDF3, ENG, ACVRL1, GDF7, COMP, ROR2, GDF2, FAM83G, LEFTY2, SMAD9, GDF1, DSG4, SMAD5, GDF5 |
| BMP signaling pathway involved in heart development | biological process | ACVR1, BMPR1A, MSX1, MSX2 |
| BMP signaling pathway involved in heart induction | biological process | BMP4, BMP2 |
| BMP signaling pathway involved in mesodermal cell fate specification | biological process | ETV2 |
| BMP signaling pathway involved in nephric duct formation | biological process | BMP4 |
| BMP signaling pathway involved in renal system segmentation | biological process | BMP4 |
| BMP signaling pathway involved in spinal cord dorsal/ventral patterning | biological process | CHRD |
| BMP signaling pathway involved in ureter morphogenesis | biological process | BMP4 |
| body fluid secretion | biological process | ANXA2, SLC22A2, NPR1, SLC22A4, EDN1, GUCA2B |
| body morphogenesis | biological process | GPC3 |
| bombesin receptor signaling pathway | biological process | NMBR, BRS3 |
| bone development | biological process | HSD17B1, SRD5A2, GNAS, BGLAP, FGFR2, SRD5A1, BMP4, FGF8, PPIB, RPL13, TULP3, RARB, ASXL1, CHAD, DYM, TMEM38B, COL2A1, MCPH1, PHEX, SLC38A10, SMPD3, BGN, MMP16, BBX, NSD2, TRIP11, ANKRD11, MMP14, TWIST1, PTGER4, AKAP13, PAPSS2, TTC9, LRP5, AMER1, P3H1, MIGA2, SULF1, PDGFC, ENG, HOXA11, RARG, SPNS2, SH3PXD2B, NPR2, CCN4, SLC10A7, SULF2, IFT172, PRPSAP2, SMAD5, MYOC, VKORC1, RARA |
| bone growth | biological process | LEP, LEPR, SMPD3, COMP |
| bone marrow development | biological process | SBDS, ASXL1, PTPRC, HOXB4, LRRC17, LRP5, LRP5L, TP53 |
| bone maturation | biological process | FGFR3, GH1, MBTPS2 |
| bone mineralization | biological process | PTGS2, BGLAP, ERCC2, FGFR2, FGFR3, SBDS, LGR4, ZMPSTE24, CER1, PTN, PTH1R, SNX10, GPNMB, ASPN, TMEM38B, SBNO2, ASGR2, ATF4, PHEX, RSPO2, SMPD3, MINPP1, COL1A2, LOX, CYP27B1, KLF10, CLEC3B, SLC24A3, TUFT1, WNT11, FGR, MMP13, PTHLH, AXIN2, BMP2, COMP, GPC3, ROR2, PKDCC, ZBTB40, EIF2AK3 |
| bone mineralization involved in bone maturation | biological process | LEP, IGF1, ANO6, PHOSPHO1, IFT80, BMP2 |
| bone morphogenesis | biological process | FGFR2, FGFR3, LTF, CYP26B1, DHRS3, CHSY1, SKI, MSX1, HAS2, PAPPA2, LRP6, TFAP2A, GLG1, IFT80, PAX1, LRP5, MMP13, DLX5, SFRP2, MSX2, LTBP3, CDX1, SFRP4, RARG, COMP, LRP5L, OSR2 |
| bone regeneration | biological process | FZD9, POSTN, CCN3, LGR6 |
| bone remodeling | biological process | IL6, LGR4, MITF, LRP6, TPH1, RASSF2, TRAF6, EFNA2, LRP5, HTR1B, EPHA2, LTBP3, P3H4, LRP5L, SPP2, WNT16 |
| bone resorption | biological process | CTNNB1, SRC, CTSK, IL7, PTH1R, SNX10, ADRB2, NCDN, TPP1, RAC1, RAC2, TRAF6, GPR55, TCIRG1, RAB3D, IHH, PTK2B, LRRK1, ZNF675 |
| bone trabecula formation | biological process | MMP2, FBN2, MSX2, WNT10B, PPARGC1B, THBS3 |
| bone trabecula morphogenesis | biological process | SBNO2 |
| borate transmembrane transport | biological process | SLC4A11 |
| borate transport | biological process | SLC4A11 |
| box C/D snoRNA 3'-end processing | biological process | FBL |
| box C/D snoRNP assembly | biological process | ZNHIT3, RUVBL2, SNU13, NUFIP1, RUVBL1, PIH1D2, ZNHIT6, TAF9 |
| box H/ACA snoRNA 3'-end processing | biological process | DKC1, PARN |
| box H/ACA snoRNA metabolic process | biological process | DKC1 |
| box H/ACA snoRNP assembly | biological process | SHQ1, NAF1 |
| bradykinin catabolic process | biological process | CPN1, ECE1, IDE, XPNPEP1, CTSH |
| brain development | biological process | FAS, BRCA1, BRCA2, BAX, BAK1, DNMT1, ATM, NODAL, ARNT2, FGFR1, ACAT1, MTOR, BAG6, BMP4, NRG1, BMPR2, CD9, EMX1, PTPN11, VCY, NF2, PAFAH1B2, DSCAML1, PYGO2, 38231, SYNJ1, B4GALT2, GLI3, ARF4, KIF5B, UBE3A, COX17, KCNAB1, NNAT, GJC2, CNTN4, RAB18, MYH10, CXCR4, DPYSL2, JHY, FOXJ1, SPHK2, STK36, BAIAP2, NKX2-2, ZIC2, XRCC5, PBX2, PPT1, EXT1, MDGA1, CDK5RAP1, TULP3, GRIN1, HNRNPD, NCOA6, DNAJC30, ALK, NDUFS4, BCL2L11, EOMES, EEF1AKMT4-ECE2, PTN, STAR, MACROH2A2, CTNS, NEURL1, CDK5RAP2, NDRG4, CTNND1, ACSL3, COL4A1, GNAI3, BCR, PBX3, PPP3CC, ABR, ASPM, CDK5RAP3, MACROD2, NFIB, SYNJ2, BAG3, AK4, STMN1, S1PR1, SYT1, NOTCH1, MACO1, CTTNBP2, CITED1, ARL6, ROBO2, FZD3, TBC1D23, SNPH, WDR47, XRCC6, PTPRG, SELENOP, HPCA, ZFHX3, TBR1, IRS2, SNRPB, GABRA5, OXCT1, HMGCS1, HYDIN, ZNF335, MEN1, APOD, CASP2, PSEN1, AFF2, EMX2, MEIS3, UTP3, CNTNAP2, SLC6A11, ATXN1, UNC5C, ATXN1L, EPOR, PBX1, RGS2, MECP2, RIDA, GRIN2C, CDK5R1, C2CD3, NIPBL, SHARPIN, PHF8, SIX3, SMARCA1, SLC6A4, ID4, PRKDC, PPP3CA, BPTF, MAP1S, AMIGO3, IMMP2L, VC |
| brain morphogenesis | biological process | PTEN, EMX1, BBS2, FANCD2, MKKS, CTNNA2, BBS4, ZNF335, SHANK2, PSEN1, SLC6A4, FANCC, FOXO3, SHANK1, SLC4A10 |
| brain segmentation | biological process | HOXA2, EGR2 |
| brain-derived neurotrophic factor receptor signaling pathway | biological process | BDNF, RAPGEF2, NTRK2, NFATC4, SLC9A6 |
| brainstem development | biological process | GART, ATIC, SMAD4, NLGN4X, PHOX2B, CNTFR, SCN5A |
| branch elongation involved in mammary gland duct branching | biological process | TGFB1 |
| branch elongation involved in salivary gland morphogenesis | biological process | FGFR2, FGF10 |
| branch elongation involved in ureteric bud branching | biological process | FGF1 |
| branch elongation of an epithelium | biological process | HOXD13 |
| branched-chain amino acid biosynthetic process | biological process | BCAT1, BCAT2 |
| branched-chain amino acid catabolic process | biological process | ACAT1, HIBADH, BCKDHB, HIBCH, IVD, AUH, MCCC1, BCAT1, PPM1K, ALDH6A1, MCCC2, ACADSB, SLC25A44, HSD17B10, ACAD8, BCAT2, BCKDHA |
| branched-chain amino acid metabolic process | biological process | BCAT1, BCAT2 |
| branched-chain amino acid transport | biological process | SLC38A9, SLC38A7, SLC25A44 |
| branching involved in blood vessel morphogenesis | biological process | VEGFA, EDNRA, CTNNB1, FGF8, SHH, SEMA3E, RBM15, STK4, ACVR1, COL4A1, FOXC2, NRARP, LEF1, NFATC4, NOTCH4, TBX20, SFRP2, SRF, TGFBR2, EDN1, GBX2, ENG, NRP1, IHH, GDF2, PLXND1 |
| branching involved in labyrinthine layer morphogenesis | biological process | IL10, ADM, FGFR2, SPINT1, GRB2, RSPO3, FZD5, SOCS3, GCM1 |
| branching involved in mammary gland duct morphogenesis | biological process | SRC, DDR1, CSF1, KDM5B, BTRC, CCL11, LRP6, PML, TBX3, LRP5, EPHA2, MSX2, LRP5L |
| branching involved in pancreas morphogenesis | biological process | PROX1 |
| branching involved in prostate gland morphogenesis | biological process | FGFR2, BMP4, SHH, NKX3-1, FEM1B |
| branching involved in salivary gland morphogenesis | biological process | IL6, FGFR2, FGFR1, BMP7, FGF8, SHH, TGM2, ESRP2, FGF7, DAG1, LAMA5, FGF10 |
| branching involved in ureteric bud morphogenesis | biological process | BCL2, WT1, SOX9, CTNNB1, PGF, BMP4, FGF8, SHH, MYC, GDNF, GLI3, SMAD4, GZF1, CTNNBIP1, DCHS1, WNT4, WNT9B, CITED1, PAX8, PKD2, HOXD11, LHX1, PBX1, DLG1, GREB1L, SIX1, ILK, EYA1, BMP2, SALL1, FGF2, HOXA11, LAMA5, GPC3, PTCH1, WNT6 |
| branching morphogenesis of a nerve | biological process | FGFR2, RERE, EPHA7, DRD2, DLX2 |
| branching morphogenesis of an epithelial tube | biological process | EGF, VEGFA, HNF1B, BMP7, BMP4, SHH, PKD1, MYCN, GLI3, NKX3-1, WNT4, CLIC4, WNT9B, NOTCH1, TIMELESS, MMP14, SPRY2, GDF7, LAMA5, GLI2, SLIT2, RASIP1, FGF10 |
| branchiomotor neuron axon guidance | biological process | SEMA3A, SEMA3F, MYCBP2, PLXNA4, NRP1, PLXNA3 |
| brassinosteroid biosynthetic process | biological process | DHCR7 |
| bronchiole development | biological process | HOXA5 |
| bronchiole morphogenesis | biological process | FGF10 |
| bronchus cartilage development | biological process | SOX9, SRF |
| bronchus development | biological process | BMP4, TGFBR2 |
| bronchus morphogenesis | biological process | TULP3, TGFBR2 |
| brown fat cell differentiation | biological process | PTGS2, ITGA6, EBF2, PLAC8, PPARGC1A, ADIPOQ, FABP3, ADRB2, ERO1A, UCP1, ALDH6A1, RGS2, BNIP3, ADIG, LRG1, DIO2, PEX11A, MB, SLC2A4, ADRB1, LAMB3, PRDM16, METRNL, ZNF516, ARL4A |
| brush border assembly | biological process | USH1C, MYO7B |
| bud dilation involved in lung branching | biological process | BMP4 |
| bud elongation involved in lung branching | biological process | FGFR2, BMP4, SPRY1, YAP1, SPRY2, RDH10, FGF10 |
| bud outgrowth involved in lung branching | biological process | SHH, TNC, FGF10 |
| bundle of His cell action potential | biological process | SCN5A, SCN10A |
| bundle of His cell to Purkinje myocyte communication | biological process | TNNI3K |
| bundle of His cell to Purkinje myocyte communication by electrical coupling | biological process | GJA5 |
| bundle of His cell-Purkinje myocyte adhesion involved in cell communication | biological process | CTNNA3, DSP, PKP2, DSG2, DSC2, JUP |
| bundle of His development | biological process | TBX5, ID2, NKX2-5 |
| butyrate catabolic process | biological process | ACADS |
| butyrate metabolic process | biological process | ACSM1, ACOT4 |
| C-5 methylation of cytosine | biological process | DNMT1, DNMT3B, STPG4 |
| C-terminal protein deglutamylation | biological process | AGBL4, FOLH1B, FOLH1, AGBL1 |
| C-terminal protein lipidation | biological process | ATG12, ATG5, GPLD1 |
| C-terminal protein methylation | biological process | LCMT1 |
| C-terminal protein-tyrosinylation | biological process | TTL |
| C21-steroid hormone biosynthetic process | biological process | CYP11A1, CYP11B1, CYP11B2, AKR1B1, STAR, STARD3NL, FDX1, FDX2, STARD3 |
| C21-steroid hormone metabolic process | biological process | CYP11A1, DHRS2, AKR1C2, CYP46A1, AKR1D1, AKR1C1, AKR1C4 |
| CAAX-box protein processing | biological process | ZMPSTE24, RCE1 |
| cadmium ion homeostasis | biological process | MT3 |
| cadmium ion transmembrane transport | biological process | SLC39A8, SLC30A1, SLC11A1, SLC39A14 |
| Cajal body organization | biological process | FAM118B, WRAP53, ZPR1, USPL1 |
| Cajal-Retzius cell differentiation | biological process | PSEN1 |
| calcineurin-mediated signaling | biological process | PPP3CB, PPP3CC, PPP3CA, SULT1A3 |
| calcineurin-NFAT signaling cascade | biological process | NFATC1, PPP3CB, PPP3CC, NFATC3, NFATC2, PPP3CA, NFAT5, ADGRB2, NFATC4, RCAN1, PPP3R1 |
| calcitonin catabolic process | biological process | ECE1 |
| calcitonin gene-related peptide receptor signaling pathway | biological process | CALCRL, CALCA, RAMP1 |
| calcitriol biosynthetic process from calciol | biological process | CYP2R1, CYP27B1 |
| calcium activated galactosylceramide scrambling | biological process | ANO6, ANO7, ANO9, ANO4 |
| calcium activated phosphatidylcholine scrambling | biological process | ANO6, ANO7, ANO9, ANO4 |
| calcium activated phosphatidylserine scrambling | biological process | ANO6, ANO7, ANO9, ANO4 |
| calcium activated phospholipid scrambling | biological process | ANO6, ANO7, ANO9, ANO4 |
| calcium export from the mitochondrion | biological process | LETM1, SLC8B1 |
| calcium import into the mitochondrion | biological process | MAIP1, OPA1, SMDT1, MICU2, AFG3L2, MCUR1, MCUB, MICU1, SLC25A23 |
| calcium ion export | biological process | SLC8A1, ATP2B1 |
| calcium ion export across plasma membrane | biological process | SLC8A3, ATP2B3, ATP2B1, SLC8A2 |
| calcium ion homeostasis | biological process | ADM, WFS1, ATP6V1B1, TRIM24, GRIN1, SNCA, SNX10, TMTC2, CALB1, SELENON, JPH2, STC2, SGCD, CYP27B1, FAM20A, CIB2, SLC8A1, CCDC47, ASPH, HRC, KL, TRPV6, CAV1 |
| calcium ion import | biological process | CACNA1E, CACNA1C, CACNA1A, SLC30A1, SLC8A1, CACNA1G, MCUR1, CACNA1I, CASK, CACNA1H, CDK5, TRPC4, CACNA1D, MICU1, ATP2A1, GCK, CACNA1B, CACNB2 |
| calcium ion import across plasma membrane | biological process | FAM155B, SLC8A3, TRPV2, FAM155A, TRPV3, TRPM2, TRPV6, SLC24A1, TRPV1 |
| calcium ion import into cytosol | biological process | MS4A1 |
| calcium ion import into sarcoplasmic reticulum | biological process | ATP2A2, ZMPSTE24, ATP2A1 |
| calcium ion regulated lysosome exocytosis | biological process | SYT7 |
| calcium ion transmembrane import into cytosol | biological process | GRIN1, GRIN2C, GRIN2B, GRIN2A, TRPM2, GRIN2D |
| calcium ion transmembrane transport | biological process | CATSPER1, CATSPER2, GAS6, IL1RAPL1, ITGAV, CACNA2D1, PKD1, CATSPER4, CATSPER3, ANXA5, CACNA1S, ATP2A2, ASIC1, TRPC3, TRPC4AP, TMEM165, CACNA1E, SLC24A5, SLC24A4, CACNG2, GPM6A, ANO6, PKDREJ, RYR1, RYR2, CACNG6, CACNA1C, CACNG3, CACNG7, ATP2C1, TMEM37, PANX1, ANXA9, PKD2, PKD2L1, TRPA1, ITPR3, P2RY12, CACNA2D2, CACNA1A, CHRNA7, PSEN1, SLC8A3, CUL5, CHRNA10, TRPM3, TRPV2, STIM2, TRPC7, CACHD1, SLC8A1, NCS1, CACNA1G, ATP2B3, ASPH, ITPR1, MCOLN3, CACNA1I, TRPC1, TPCN2, ATP2A3, P2RX7, SLC24A3, CACNG4, CACNB4, ITPR2, GRIN3A, TRPC5, CALHM1, CACNA1H, ATP2B1, TRPC4, SEC61A1, CACNA1D, CACNB1, CACNG1, TRPM4, TMC1, P2RX4, GRIN3B, CACNB3, SLC25A25, PKD1L2, ATP2A1, ATP2B2, TRPM1, TRPV3, MCOLN1, TRPM5, ATP2C2, TRPM2, CACNA1B, SLC8B1, CACNA2D4, ORAI2, SLC8A2, NALCN, MCOLN2, CACNA2D3, TRPM6, TPCN1, CACNB2, TMC2, CACNG8, ORAI3, TRPV6, SLC24A1, TRPV1 |
| calcium ion transmembrane transport via high voltage-gated calcium channel | biological process | CACNA2D1, CACNA1C, CACNB3 |
| calcium ion transmembrane transport via low voltage-gated calcium channel | biological process | WNT3A |
| calcium ion transport | biological process | VDR, CATSPER1, CATSPER2, CCL5, CACNA2D1, CCR5, PLCZ1, PKD1, CATSPER4, CATSPER3, ANXA6, CACNA1S, ATP2A2, SRI, ASIC1, CCR1, CCL8, SARAF, GRIN1, TRPC3, CYSLTR1, CACNA1E, CALCRL, SLC24A5, SLC24A4, CACNG2, CCL3, KCNN4, RYR1, RYR2, CACNG6, SLN, RAMP2, CACNA1C, CACNG3, CACNG7, ATP2C1, BSPRY, TMEM37, PANX1, PKD2, EFHB, PKD2L1, TRPA1, ITPR3, CACNA2D2, CACNA1A, CHRNA7, PSEN1, SLC8A3, CHRNA10, TRPM3, TRPV2, PRKCB, CRACR2A, SMDT1, STIM2, TRPC7, CYP27B1, PLN, PPP3CA, CACHD1, SLC8A1, CACNA1G, ATP2B3, MCUR1, ITPR1, CACNA1I, TRPC1, TPCN2, ATP2A3, P2RX7, NMUR2, NMUR1, SLC24A3, CACNG4, CACNB4, RAMP3, TPT1, ITPR2, GRIN3A, MCUB, TRPC5, CALHM1, CACNA1H, ATP2B1, GJA4, PSEN2, TRPC4, SLC3A2, CORO1A, CACNA1D, CACNB1, CACNG1, GRIN2A, TRPM4, RAMP1, CHRNB2, CHRNA4, CACNB3, MICU1, ATP2A1, LETM1, ATP2B2, TRPV3, MCOLN1, ATP2C2, TRPM2, CACNA1B, SLC8B1, CACNA2D4, CDH23, SLC8A2, MCOLN2, CACNA2D3, TRPM6, TPCN1, CAMK2A, CACNB2, STIM1, CACNG8, TRPV6, SLC24A1, CAV1, TRPV1 |
| calcium ion transport from cytosol to endoplasmic reticulum | biological process | ATP2A2, ATP2A3 |
| calcium ion transport into cytosol | biological process | CACNA2D1, JPH4, RYR2, CACNA1C, JPH3, ITPR3, ADRA1A, SLC8A3, JPH2, SLC8A1, CACNB3, JPH1, TRPM1 |
| calcium ion-regulated exocytosis of neurotransmitter | biological process | RIMS2, RIMS1, SYT1, SYT5, STX1B, SYT12, SYT6, SYT9, RIMS3, SYT7, SYT2, SYT3, DOC2B, SYT10, RIMS4 |
| calcium-dependent activation of synaptic vesicle fusion | biological process | PRRT2, SYT1, SYT9, SYT7 |
| calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules | biological process | PCDHB9, CDH7, DCHS1, CDH10, NRXN1, CDH19, ARVCF, AJUBA, PCDHB4, ATP2C1, PCDHB3, SELP, CDH12, DSG1, CDH17, PCDHB14, PCDHB16, PCDHB5, CDH6, CDH9, PCDHB10, CDH5, CDH8, CDH11, CDH13, PCDH12, CDH16, SELL, PCDHGB4, CDH3, CDH4, CDH15, CDH24, CDH23, CDHR3, CDH26, CDH22, PCDHB2 |
| calcium-dependent cell-matrix adhesion | biological process | DAG1 |
| calcium-dependent self proteolysis | biological process | CAPN3 |
| calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | biological process | CLDN11, CLDN14, CLDN6, CLDN2, CLDN9, CLDN15, CLDN12, CLDN5, CLDN16, CLDN18, CLDN23, CLDN17, CLDN10, CLDN1, CLDN7, CLDN4, CLDN8 |
| calcium-independent cell-matrix adhesion | biological process | ITGB1, FN1, PKD1, VWA2 |
| calcium-ion regulated exocytosis | biological process | RIMS2, SCIN, SYT13, RIMS1, PPP3CB, SYT1, SYT5, ARHGAP17, SYT12, VAMP3, VAMP7, CHP1, SYN2, SYT17, SYT6, SYT9, RIMS3, SYT7, SYT2, SYT3, SYT15, SYT10, RAPGEF4 |
| calcium-mediated signaling | biological process | CXCL8, GPRC6A, KISS1R, CCR5, ACKR4, CXCR4, NUDT4, CCR1, GRIN1, P2RY11, PPP1R9B, RCAN2, TREML1, CALML6, CCL3, XCR1, MCTP2, RYR2, LAT2, CXCR5, HPCA, ACKR3, AGTR1, P2RY12, CHRM3, CXCR2, CCR6, PLCE1, CALM1, CALM2, CALM3, EDNRB, MCTP1, GRIN2C, SGCD, PPP3CA, EFCAB11, RCAN3, CX3CR1, GRIN2B, BHLHA15, CCRL2, CXCR3, BTK, TPCN2, CALML4, NMUR2, NMUR1, PPP1R9A, PTGDR2, RCAN1, CALML5, CXCR1, FPR2, CCR7, CXCR6, EDN1, SAMD14, LAT, CALML3, CCR10, NCALD, GRIN2A, TRPM4, P2RX4, CAMKK2, PDPK1, MCOLN1, GRIN2D, PLCG2, CCR3, KSR2, LRRK2, EIF2AK3, ACKR2, HTR2B, CCR4 |
| calcium-mediated signaling using extracellular calcium source | biological process | CACNA1C, P2RY12, P2RX7, DMTN |
| calcium-mediated signaling using intracellular calcium source | biological process | KDR, PRNP, CCL20, ADGRL1, VCAM1, RYR2, HOMER2, DEFB1, PTPRC, SELP, STIMATE, TENM2, BCAP31, FIS1, FKBP1B, AZU1, DMTN, TRPM2, GPR143, GRM5 |
| calmodulin dependent kinase signaling pathway | biological process | PCP4 |
| camera-type eye development | biological process | CYP1A1, WT1, BMP4, SHH, CHD7, ALDH1A2, GLI3, CRYBA4, FBN2, CRYAB, FBN1, B9D1, ARHGAP35, CACNA1C, TBC1D20, MITF, SKI, NEUROD4, NEUROD1, SLITRK6, MAB21L2, SIX3, TBC1D32, FOXC2, TWSG1, FOXP2, PKNOX1, VAX2, FKBP8, TSKU, RAX, FOXC1, RAB3GAP1, LIM2, SLC25A25, MTERF4, JAG1, SHROOM2, IHH, HSF4, STRA6, CRYBB2, CC2D2A, FOXE3, RPE65, RPGRIP1L, GPD2, EFEMP1, PITX2 |
| camera-type eye morphogenesis | biological process | VEGFA, HIF1A, BMP7, BMP4, AQP5, GLI3, FAT1, EPHB2, C12orf57, COL8A1, GDF11, SKI, EPHB1, YY1, MFN2, COL8A2, NECTIN1, IFT122, RING1, SHROOM2, TENM3, NF1 |
| camera-type eye photoreceptor cell differentiation | biological process | DSCAM, SDK2, ROM1 |
| camera-type eye photoreceptor cell fate commitment | biological process | IHH |
| CAMKK-AMPK signaling cascade | biological process | ZMPSTE24, IRGM, CAMKK2 |
| cAMP biosynthetic process | biological process | ADM, ADCY2, ADCY10, ADCY6, ADCY8, ADCY7, ADCY9, ADCY4, ADCY5 |
| cAMP catabolic process | biological process | PDE4C, PDE7A, PDE7B, PDE4B, PDE4D, PDE8A, PDE10A, PDE8B, PDE4A |
| cAMP metabolic process | biological process | PTHLH, EPHA2 |
| cAMP-mediated signaling | biological process | ADM, SOX9, ADCY2, RIMS2, RAPGEF2, NDUFS4, SLC9A3R1, EIF4EBP2, DEFB1, GHRHR, GLP1R, PDE3A, KSR1, MAPK7, PDE4D, RAPGEF3, ADCYAP1R1, PDE2A, GAL, HTR5A, DGKQ, AKAP6, RAPGEF4 |
| canalicular bile acid transport | biological process | ABCC3, AQP9, ABCB11 |
| cannabinoid biosynthetic process | biological process | ALOX15B |
| cannabinoid signaling pathway | biological process | CNR1, GPR55 |
| canonical glycolysis | biological process | GAPDH, ENO1, GAPDHS, PGK1, PGAM1, ADPGK, PFKM, PFKP, PGM2L1, ENO2, PKM, ALDOB, BPGM, ALDOA, PGAM2, TPI1, GPI, FOXK2, HK2, ENO3, ALDOC, PFKL, GCK, HK3, FOXK1, PKLR |
| canonical Wnt signaling pathway | biological process | EGF, GSK3B, UBE2B, CTNNB1, PTEN, PROP1, FGF8, CDC42, SHH, PYGO2, TCF7L2, MYC, RYK, TCF7, KLF4, FZD9, FZD8, TCF7L1, FZD4, BCL9, CSNK1E, DVL1, WNT10A, WNT7B, WNT4, FZD2, FRZB, DISC1, WNT9B, WNT3A, FZD3, WNT2B, WNT8B, FZD7, LRP6, NR4A2, DVL2, BCL9L, PYGO1, LEF1, LRP5, WNT11, GLI1, MED12, SFRP2, FZD5, DVL3, WNT10B, PLPP3, SFRP5, FZD6, SFRP4, RARG, LRP5L, WNT9A, WNT3, FZD1, WNT6, WNT7A, SDC1, WNT5B, RECK, DIXDC1, LRRK2, WNT16 |
| canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological process | WNT3A |
| canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation | biological process | WNT3, FZD1 |
| canonical Wnt signaling pathway involved in metanephric kidney development | biological process | LGR4, GATA3 |
| canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological process | WNT3 |
| canonical Wnt signaling pathway involved in negative regulation of apoptotic process | biological process | CTNNB1, TCF7, MITF |
| canonical Wnt signaling pathway involved in neural crest cell differentiation | biological process | LRP6 |
| canonical Wnt signaling pathway involved in osteoblast differentiation | biological process | WNT3, FZD1 |
| canonical Wnt signaling pathway involved in positive regulation of apoptotic process | biological process | GSK3B |
| canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation | biological process | CTNNB1 |
| canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion | biological process | PLPP3 |
| canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration | biological process | PLPP3 |
| canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition | biological process | CTNNB1, TCF7L2 |
| canonical Wnt signaling pathway involved in positive regulation of wound healing | biological process | PLPP3 |
| canonical Wnt signaling pathway involved in regulation of cell proliferation | biological process | LRP6, DVL2 |
| canonical Wnt signaling pathway involved in stem cell proliferation | biological process | WNT3 |
| cap-dependent translational initiation | biological process | EIF3D |
| cap-independent translational initiation | biological process | RBM4 |
| cap1 mRNA methylation | biological process | CMTR2, CMTR1 |
| cap2 mRNA methylation | biological process | CMTR2 |
| carbamoyl phosphate biosynthetic process | biological process | CPS1 |
| carbohydrate biosynthetic process | biological process | CHST12, NANS, CHST9, CHST13, CHST10, CHST14, CHST8, CHST11 |
| carbohydrate catabolic process | biological process | AMY2A, DERA, NAGA, ENOSF1 |
| carbohydrate derivative biosynthetic process | biological process | GFPT1 |
| carbohydrate derivative metabolic process | biological process | GFPT1 |
| carbohydrate derivative transport | biological process | TMEM241, SLC35D2, SLC35E3 |
| carbohydrate homeostasis | biological process | TENT4B, VGF |
| carbohydrate mediated signaling | biological process | CLEC7A, COLEC12 |
| carbohydrate metabolic process | biological process | IGF2, AKT1, GSK3B, HEXA, HEXB, AMY2A, INSR, FUT4, LDHC, G6PD, SPAM1, MAN2B1, LDHA, GBA, GAA, GLB1, DCXR, B4GALT2, FUCA1, LDHB, GALT, AKR1B1, SLC2A5, SLC35A1, GK2, PDK4, ADPGK, SLC2A3, GK, GLO1, MLEC, PDK3, B3GAT1, GLA, PDHA1, MDH2, PHKB, CHST12, B4GALT4, PGM3, MDH1, PPP1R2, B4GALNT1, MAN2A1, PGM2L1, FGGY, MGAM, AKR7A2, SI, PPP1R3D, UGDH, GUSB, PGM1, ME1, GBE1, B3GLCT, HEXD, SIAE, B4GALT3, CHI3L1, FBP1, MAN2A2, PPP1CB, GANC, NPL, LCT, ADRB3, MPI, TALDO1, KHK, SLC3A1, FUT5, PGGHG, PPP1R3C, MANBA, BPGM, GNPDA1, PPP1R1A, HKDC1, POFUT2, GLT6D1, GNPDA2, ST8SIA2, ST6GAL2, SHPK, PHKG2, PGM5, CHST9, B3GAT2, PDHB, GALE, IDNK, HYAL3, ALDH2, NAGA, IDH2, CTBS, GK5, PPP1R3B, GPD1L, RPE, FUCA2, B4GALT6, GPI, GALK2, PDK1, CHST13, GALM, PGP, H6PD, B4GALT1, IDH3G, MDH1B, NANP, CHST6, RBKS, SLC2A8, HK2, PGM2, LDHAL6B, B4GALT5, CS, SLC2A4, PHKA2, HYAL2, CHI3L2, CHST4, ST8SIA1, NEU1, STBD1, PYGL, PYGB, IDH3A, CHID1, FUT9, HAS3, FBP2, CHST10, IDUA, GLB1L3, MAN2C1, NAGPA, XYLB, PGLS, TFF1, SLC5A2, GLB1L, CHST14, CASD1, PIGQ, POMT1, |
| carbohydrate phosphorylation | biological process | FGGY, TKFC, GNE, KHK, PFKFB2, HKDC1, NAGK, FCSK, GALK2, RBKS, HK2, POMK, GNPTG, XYLB, PFKFB4, GALK1, GCK, HK3 |
| carbohydrate transmembrane transport | biological process | SLC17A5, TMEM144 |
| carbohydrate transport | biological process | AKT1, SLC2A5, SLC35A1, SLC2A3, SLC35B1, SLC35D1, MFSD4B, SLC35D2, SLC35A5, SLC35A3, SLC2A10, SLC37A3, MFSD2A, PEA15, SLC2A14, SLC2A8, SLC37A4, SLC35A4, SLC2A11, SLC2A4, SLC37A1, SLC50A1, SLC5A1, SLC5A2, SLC35A2, SLC35C1, RFT1, MFSD12, SLC2A6, MFSD2B, AKT2, SLC35D3, SLC2A7, SLC45A1, SLC37A2 |
| carbon catabolite regulation of transcription | biological process | USF1 |
| carbon dioxide transmembrane transport | biological process | AQP1, RHAG |
| carbon dioxide transport | biological process | AQP5, CA2, AQP1, RHAG |
| carbon tetrachloride metabolic process | biological process | CYP2E1 |
| carboxylic acid catabolic process | biological process | PON1 |
| carboxylic acid metabolic process | biological process | MIF, LDHC, LDHA, LDHB, CSAD, MDH2, MDH1, PDXDC1, DDC, GAD1, GADL1, LDHAL6B, GAD2 |
| carboxylic acid transmembrane transport | biological process | AQP9, SLC16A1 |
| carboxylic acid transport | biological process | AQP9 |
| cardiac atrium formation | biological process | MESP1 |
| cardiac atrium morphogenesis | biological process | SOS1, NOTCH1, ENG |
| cardiac cell development | biological process | MTOR |
| cardiac cell fate determination | biological process | ISL1, MESP1 |
| cardiac cell fate specification | biological process | TENM4 |
| cardiac chamber development | biological process | ARID1A, TBX3, TBX2 |
| cardiac chamber formation | biological process | NOTCH1, TBX20 |
| cardiac conduction | biological process | CACNA2D1, GJA1, MEF2A, CACNA1S, ZMPSTE24, CACNG2, KCNH2, KCND3, CACNG6, CACNA1C, KCND2, CACNG3, CACNG7, KCNIP4, KCND1, SCN1B, CACNA2D2, ABCC9, AKAP9, KCNJ4, CACNG4, CACNB4, GJA5, KCNJ2, KCNIP1, KCNK1, KCNK15, KCNE1, KCNIP2, KCNK3, CACNA1D, CACNB1, CACNG1, TRPM4, CACNB3, KCNJ12, KCNIP3, SLC4A3, SCN5A, CACNA2D4, SPTBN4, CACNA2D3, CACNB2, CACNG8, SCN3B, KCNK6 |
| cardiac conduction system development | biological process | NRG1, CDC42, BMPR1A, GJA5, NKX2-5 |
| cardiac endothelial to mesenchymal transition | biological process | SEMA3C |
| cardiac epithelial to mesenchymal transition | biological process | TGFBR3, OLFM1, RTN4, NOTCH1, TGFB2, TGFBR1, HEY2, BMP2, HEY1, WNT16 |
| cardiac left ventricle formation | biological process | TBX5 |
| cardiac left ventricle morphogenesis | biological process | NOTCH1, RBPJ, HEY2, SFRP2, CPE, TGFBR2, FOXF1, NPY5R |
| cardiac muscle cell action potential | biological process | DMD, KCNJ2, SLC4A3 |
| cardiac muscle cell action potential involved in contraction | biological process | CACNA2D1, FGF12, CACNA1C, SCN1B, CACNA1G, SCN1A, PKP2, KCNJ2, ATP1A1, KCNE1, CACNA1D, SCN4B, SCN5A, SCN2B, SCN3B |
| cardiac muscle cell apoptotic process | biological process | HSP90AA1, GNB1, GNGT1, BNIP3 |
| cardiac muscle cell contraction | biological process | CAMK2D, SLC9A1, SGCD |
| cardiac muscle cell development | biological process | MTOR, HNRNPU, ALPK2, SGCB, ACTN2, CAV3, SLC8A1, ALPK3 |
| cardiac muscle cell differentiation | biological process | ITGB1, NRG1, GATA4, KDM6B, TSC1, SLC9A1, MEF2C, CBY1, CACYBP, TBX5, SOX6, AKAP13, ARID1A, MYOCD, TBX3, BMP2, MESP1, NKX2-5, SIK1, CALR |
| cardiac muscle cell fate commitment | biological process | WT1, ACVR1, WNT3A, TBX3 |
| cardiac muscle cell myoblast differentiation | biological process | NRG1, ISL1, REST |
| cardiac muscle cell proliferation | biological process | TGFBR3, ARID2, NDRG4, NOTCH1, TGFB2, FOXC2, DIPK2A, FOXC1, NKX2-5, TENM4 |
| cardiac muscle cell-cardiac muscle cell adhesion | biological process | DSC2 |
| cardiac muscle contraction | biological process | MYH7, MTOR, PIK3CA, TPM1, GAA, CXCR4, TCAP, DMD, MYL4, KCNH2, CASQ2, RYR2, MYBPC3, ACTC1, GRK2, MAP2K3, SCN1B, TTN, ATP1A2, SGCD, CSRP3, SLC8A1, MAP2K6, ATP1B1, TNNI2, MYL2, VEGFB, TNNT1, NKX2-5, SCN4B, MYL3, MYH6, TNNT3, SCN5A, MYLK2, SCN2B, TNNI1, SMAD5, SCN3B, PPP1R13L |
| cardiac muscle fiber development | biological process | VEGFA, TCAP, MYOM2, ZMPSTE24, MYH11, MYOM3, TTN, SGCD, CXADR, MYO18B, MYH6, MYOM1 |
| cardiac muscle hypertrophy | biological process | LEP, TCAP, HDAC2, RYR2, TTN, TIAM1, CSRP3, HEY2, HTR2B |
| cardiac muscle hypertrophy in response to stress | biological process | ATP2A2, HDAC4, TCAP, INPP5F, MEF2C, PPP3CA, HEY2, MYH6, CAMTA2 |
| cardiac muscle thin filament assembly | biological process | NEB, NRAP, NEBL |
| cardiac muscle tissue development | biological process | ITGB1, MTOR, PTEN, ALDH1A2, ZFPM2, GATA5, NDUFV2, BMP5, SGCD, PLN, CSRP3, NPRL3, RBP4, NKX2-5, SGCZ, GJC1, TBX2 |
| cardiac muscle tissue growth involved in heart morphogenesis | biological process | S1PR1 |
| cardiac muscle tissue morphogenesis | biological process | TCAP, MYOM2, NOTCH1, ACTC1, MYOM3, TTN, XIRP2, EGLN1, TBX20, BMP2, NKX2-5, MYOM1, MYLK2, ZFPM1, ANKRD1 |
| cardiac muscle tissue regeneration | biological process | YAP1 |
| cardiac myofibril assembly | biological process | MYH10, TCAP, MYOM2, ACTC1, MYOM3, TTN, CSRP3, OBSL1, PDGFRB, SRF, MYL2, PDGFRA, FHOD3, MYOM1, MYLK3 |
| cardiac neural crest cell development involved in heart development | biological process | MAPK3, MAPK1 |
| cardiac neural crest cell development involved in outflow tract morphogenesis | biological process | HES1, TWIST1, JAG1, HAND2 |
| cardiac neural crest cell migration involved in outflow tract morphogenesis | biological process | TWIST1, FOLR1, HAND2, PITX2 |
| cardiac right atrium morphogenesis | biological process | NOTCH1 |
| cardiac right ventricle formation | biological process | SMARCD3, NOTCH1, HAND2 |
| cardiac right ventricle morphogenesis | biological process | GATA4, ISL1, BMPR1A, GATA3, TGFB2, SOX4, HEY2, TBX20, SEMA3C, JAG1, FOXH1, PPP1R13L |
| cardiac septum development | biological process | BMP4, MYH10, SMAD4, CPLANE1, CRELD1, TAB1, PRDM1, NDST1, AP2B1, TBX20, ZBTB14, ADAMTS6, PLXND1, SNX17 |
| cardiac septum morphogenesis | biological process | MDM2, DHRS3, NOTCH1, BMP5, HEY2, HEY1, JAG1, TP53 |
| cardiac vascular smooth muscle cell development | biological process | VEGFA, NOTCH1, HEY2 |
| cardiac vascular smooth muscle cell differentiation | biological process | SRF, MESP1 |
| cardiac ventricle development | biological process | NACA, KCNK2, ZMPSTE24, GREB1L, MYOCD, TMEM65, SCN5A |
| cardiac ventricle formation | biological process | MEF2C, SOX11, SOX4, MESP1, NKX2-5 |
| cardiac ventricle morphogenesis | biological process | HIF1A, GATA4, NOTCH1, HEY2, HEY1, ENG, NKX2-5 |
| cardioblast anterior-lateral migration | biological process | MESP1 |
| cardioblast differentiation | biological process | EOMES, EEF1AKMT4-ECE2, TGFB2 |
| cardioblast migration | biological process | MESP1 |
| cardioblast migration to the midline involved in heart field formation | biological process | MESP1 |
| cardiocyte differentiation | biological process | MYOCD, BMP2 |
| cardiolipin acyl-chain remodeling | biological process | LCLAT1, THEM5, HADHB, HADHA, PLA2G4A, PLA2G5 |
| cardiolipin biosynthetic process | biological process | PLA2G6, SLC27A1, TAMM41, PTPMT1, PGS1, CRLS1 |
| cardiolipin metabolic process | biological process | MECP2 |
| cardiovascular system development | biological process | APOE, ARID2, NDUFS6, SLITRK5, SEC24B, ABL1, HSPG2, NXN, POGLUT1, CRB2, NKX2-5, SPEG, MYLK |
| carnitine biosynthetic process | biological process | ACADM, SHMT1, ALDH9A1, TMLHE |
| carnitine catabolic process | biological process | ACADL |
| carnitine metabolic process | biological process | SLC22A5, CPT1A, POR, SLC22A4, CPT1C, CPT1B |
| carnitine metabolic process, CoA-linked | biological process | ACADM, CRAT, ACADL |
| carnitine shuttle | biological process | CPT1A, MID1IP1, PRKAG2, CPT2, PRKAA2, ACACA, ACACB, CPT1B, SLC25A20 |
| carnitine transmembrane transport | biological process | SLC22A5, SLC22A16, SLC22A4 |
| carnitine transport | biological process | SLC22A5, SLC22A16, SLC22A4, SLC25A29 |
| carnosine biosynthetic process | biological process | HAO2 |
| carnosine metabolic process | biological process | CARNMT1 |
| carotene catabolic process | biological process | BCO2, BCO1 |
| carotene metabolic process | biological process | BCO2 |
| carotenoid metabolic process | biological process | BCO2 |
| carotid body glomus cell differentiation | biological process | ASCL1 |
| cartilage condensation | biological process | SOX9, PKD1, MYCN, MAPK14, COL11A1, CCN2, OTOR, COL2A1, ACAN, BMP1, SOX6, BARX2, MGP, FGF6, ROR2, THRA, WNT7A |
| cartilage development | biological process | TIMP1, CD44, SOX9, HIF1A, GNAS, MAPK3, GHRL, BMP7, BMP4, PKD1, HOXA3, COL11A1, TYMS, PAX7, BBS2, CSGALNACT1, HOXD3, CHSY1, COL11A2, BMPR1A, MKKS, CHI3L1, COL2A1, MSX1, CREB3L2, CNMD, BMP1, PRRX1, SMPD3, BMP5, TRIP11, TAPT1, HYAL3, ZEB1, SOX6, ATP7A, ITGB8, ESRRA, BMP6, HYAL2, MMP13, SFRP2, MSX2, TGFBR2, MATN3, EDN1, MGP, BMP2, SULF1, IL17F, HOXB3, ZBTB16, HOXC4, COMP, SNORC, DDRGK1, EVC, IHH, GDF2, WNT7A, SULF2, CHST11, SATB2, DLX2, SMAD5, GDF5 |
| cartilage development involved in endochondral bone morphogenesis | biological process | COL2A1, HOXA11 |
| cartilage homeostasis | biological process | CYTL1, SLC39A8, MTF1 |
| cartilage morphogenesis | biological process | HOXA5, MSX1, MEF2C, HAND2 |
| catabolic process | biological process | AADAC, PTER, TMEM150A, CES2, AFMID, NCEH1 |
| catechol-containing compound metabolic process | biological process | COMT |
| catecholamine biosynthetic process | biological process | PAH, DDC, TH, DBH |
| catecholamine catabolic process | biological process | LRTOMT |
| catecholamine metabolic process | biological process | SULT1A1, COMT, AOC2, DDC, ATP7A, LRTOMT, SULT1A3, SULT1A4, SULT1A2 |
| catecholamine secretion | biological process | MECP2 |
| catenin import into nucleus | biological process | CTNNB1 |
| cation homeostasis | biological process | UNC80 |
| cation transmembrane transport | biological process | SLC22A5, SLC38A9, SLC30A9, SLC30A5, ASIC2, SLC38A7, CHRNE, MMGT1, CNGA2, SLC47A1, TMEM63A, ABCC9, ATP1A2, PIEZO2, TMEM63C, SLC30A7, CALHM6, UNC80, CNGB3, ATP8A1, P2RX7, P2RX6, ATP1B1, AQP1, CALHM5, SLC22A4, SLC30A6, P2RX4, GRIN3B, CNGB1, P2RX5, P2RX3, TMEM63B, ANO1, MCOLN1, CALHM2, ANO10, PIEZO1, P2RX2, ASIC3, SLC22A1, CALHM4 |
| cation transport | biological process | ASIC1, SLC30A9, SLC30A5, SLC22A2, ASIC2, GRIN1, MMGT1, ATP10D, PANX3, ANO6, SLC41A1, SLC47A1, SLC30A2, SLC9C1, ATP13A2, SLC9A2, SLC9A1, PANX1, SLC9A7, ATP7B, SLC30A10, PKD2L1, CHRNB1, TMCO3, SLC9A9, SLC30A8, CHRND, TRPM3, SLC9B2, SLC30A1, SLC9C2, PIEZO2, ATP13A3, TMEM63C, ATP7A, SLC30A7, ATP13A5, CNGB3, P2RX7, CALHM1, SLC9A6, SLC30A3, ATP13A4, SLC30A6, TRPM4, CNGB1, SLC39A1, HCN4, P2RX3, ANO1, MCOLN1, ATP13A1, ANO10, TRPM5, TRPM2, SLC8B1, PIEZO1, PANX2, ASIC3, SLC22A1, TRPM6, CHRNA1, SLC30A4 |
| caudate nucleus development | biological process | FOXP2 |
| caveolin-mediated endocytosis | biological process | MAPK3, MAPK1, MLC1, PACSIN2, CAV1 |
| CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | biological process | SHH, CYLD |
| CD4-positive, alpha-beta T cell activation | biological process | RSAD2, STOML2, CDH26 |
| CD4-positive, alpha-beta T cell costimulation | biological process | CD81 |
| CD4-positive, alpha-beta T cell cytokine production | biological process | CD55 |
| CD4-positive, alpha-beta T cell differentiation | biological process | NKX2-3, RSAD2, SATB1, PAX1 |
| CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation | biological process | FUT7, PLA2G2D |
| CD40 signaling pathway | biological process | CD86, PHB2, TNIP2, RNF31, CD40 |
| CD8-positive, alpha-beta T cell activation | biological process | HLA-E, CLEC4A |
| CD8-positive, alpha-beta T cell differentiation | biological process | SATB1, PAX1, IRF1, TNFSF8 |
| CD8-positive, alpha-beta T cell differentiation involved in immune response | biological process | IFNG, EOMES |
| CD8-positive, alpha-beta T cell lineage commitment | biological process | BCL2 |
| CD80 biosynthetic process | biological process | TMEM106A |
| CD86 biosynthetic process | biological process | TMEM106A, TREX1 |
| Cdc42 protein signal transduction | biological process | SHTN1, RHOU, NTN1, WAS, RHOJ, RHOV |
| CDP biosynthetic process | biological process | CMPK1 |
| CDP phosphorylation | biological process | AK9 |
| CDP-choline pathway | biological process | CHKA, CEPT1, CHPT1, PCYT1B, CDS1, PCYT1A |
| CDP-diacylglycerol biosynthetic process | biological process | LCLAT1, AGPAT1, AGPAT2, TAMM41, AGPAT3, CDS1, GPAM, AGPAT4, GPAT3 |
| CDP-diacylglycerol metabolic process | biological process | CDIPT |
| cell activation | biological process | TIMP1, TGFB1, IGF1, FN1, CCL3, GATA3, TLR1, PDGFA, PDGFRA, TLR6 |
| cell activation involved in immune response | biological process | GBF1 |
| cell adhesion | biological process | ICAM1, CD44, KITLG, ANOS1, IGFALS, BGLAP, VWF, GAS6, CIB1, APP, ITGB1, ITGA5, CTNNB1, ITGAV, SRC, ITGA4, CD99, ITGA6, IL2, IZUMO1, PCDH17, CLDN11, FN1, CDH1, NCAM1, CD9, SPAM1, LGALS3BP, CDH18, CYP1B1, FLRT3, AZGP1, SIRPA, DDR1, DSCAML1, SIRPG, CX3CL1, MUC16, CCN1, PSTPIP1, CLDN14, ATP2A2, CCN2, CLDN6, CLDN2, CNTN4, MEGF10, ERBIN, PCDH9, SIGLEC8, HPSE, PCDHB9, LPXN, LAMC1, MYH10, ITGAE, PALLD, FERMT2, GP1BB, TNXB, CCR1, OLR1, FAT1, CDH7, NPTN, CCN6, VCAM1, PXN, CD47, PTK7, NLGN4X, SPACA4, CSF3R, FLRT1, CTNNA3, NCAM2, MPZL2, CLDN9, ITGA2B, PTPRF, ITGB5, CTNNA1, MFAP4, CLDN15, AGGF1, BVES, SIGLEC11, CD93, JCAD, PCDHGB1, CLDN5, PLXNC1, MPDZ, SPP1, BCAM, TNFAIP6, NEXN, TRO, HES1, CD226, SPECC1L, DCHS1, COL12A1, JAM3, LOXL2, CDH10, CTNND1, CNTN5, COL8A1, CD34, CCL11, NRXN1, ITGB3BP, GPNMB, CDH19, ARVCF, SIGLEC6, CTNNA2, PRKX, COL7A1, THEMIS2, MAEA, NLGN2, BCAN, AJUBA, FERMT1, NINJ2, SIGLEC7, PCDHB4, PCDHGA11, PCDHGA12, SRPX2, ITGA10, S1PR1, BCAR1, RND3, MFGE8, MADCAM1, MYBPC3, LAMA4, NEGR1, FAT3, PARD3B, SEMA4D, C |
| cell adhesion involved in heart morphogenesis | biological process | FLRT2 |
| cell adhesion involved in sprouting angiogenesis | biological process | RTN4 |
| cell adhesion mediated by integrin | biological process | ICAM1, ITGA6, ITGB5, FBN1, ITGA2, ITGB6, ITGB3, ITGB4, FYB2, ADAM9, ITGBL1, ITGB8, ITGB7, VTN, ITGB2, CCN3, COL16A1, ITGA11 |
| cell adhesion molecule production | biological process | GOLPH3, GCNT1 |
| cell aggregation | biological process | MPZ |
| cell aging | biological process | SOD1, TP53, ICAM1, BCL2, BRCA2, BGLAP, CDK1, MTOR, MIF, TP63, NPM1, RWDD1, NUP62, MORC3, ZMIZ1, PDCD4, PRELP, PML, MNT, TBX3, ILK, HRAS, TBX2 |
| cell chemotaxis | biological process | KIT, HGF, CX3CL1, CCL20, ACKR4, CXCR4, CCR1, GPR183, PDGFB, SAA4, XCR1, DEFB103A, C5, HOXB9, BCAR1, RHOG, CXCR5, PRKCQ, PIP5K1A, CCL22, DEFB4A, ACKR3, AGTR1, EPHB1, HMGB1, SAA2, CXCR2, CCR6, LOX, ELMO2, CX3CR1, PRKCD, HBEGF, BIN2, LEF1, CCRL2, CXCR3, LPAR1, CCN3, PDGFRB, CXCR1, EPHA2, CCR7, CXCR6, AZU1, CCL28, PLXNB3, CXCL14, PDGFRA, ENG, CCR10, CRK, ARRB2, ARHGEF16, CXCL12, CCR3, CCL21, CRKL, SEMA5A, DOCK4, CCL27, ACKR2, CCR4 |
| cell communication | biological process | NRG1, GJA1, CCL16, GJC2, GJD2, CTSV, OIP5, GJB1, SNTG1, FREM2, KREMEN1, GJB3, GJB5, SLC8A3, FREM3, FRAS1, ITGB4, SLC8A1, ADGRV1, ENPP5, CCL18, TRIP10, GJD4, CCL19, GJA3, GJA5, GJA4, DLL1, GJB6, JAG2, ANG, GJB4, JAG1, GJD3, SLC8A2, NF1, GJC1, GJA9, FREM1 |
| cell communication by chemical coupling | biological process | GJA1, GJA5 |
| cell communication by electrical coupling | biological process | GJA1, GJC2, GJA5, GJB6, KCNA1 |
| cell communication by electrical coupling involved in cardiac conduction | biological process | GJA1, RYR2, CACNA1C, ATP1A3, ATP1A2, SLC8A1, FKBP1B, PKP2, ATP1B1, GJA5, ATP1A1, ATP1B2, GJD3 |
| cell communication involved in cardiac conduction | biological process | GJA5, GJD3 |
| cell competition in a multicellular organism | biological process | DCAF1 |
| cell cycle | biological process | TP53, AHR, BRCA1, LIG4, BRCA2, AURKC, BIRC5, CCNB2, CDK1, CCNB1, MAPK3, MAPK1, WEE1, CDC25A, CDC25C, CDKN2A, E2F1, ATM, CTCFL, CIB1, NR3C1, CSNK2A2, GNAI1, BRSK2, RB1, SRC, MLH1, KHDRBS1, ATR, SYCP3, CDC7, H2AFX, CDC20, 39326, 41153, SYCE1, RNF8, USP8, DYNLT1, KATNB1, RASSF1, WASL, 38231, NBN, CCNA2, CCNA1, FOXM1, SYCP1, STAG3, PRNP, MCM3, RBL1, NASP, HNRNPU, CENPE, RBL2, IKZF1, TFDP1, DMC1, ABRAXAS2, SEPTIN2, CDKN3, BORA, SIAH1, RBBP8, HAUS2, BCCIP, SEPTIN9, MCM8, MCTS1, EID1, KIF2A, EVI5, CDC123, DDIT3, CETN2, CSNK1A1, RAB11A, GPSM2, E2F4, TBRG1, CACUL1, NUP37, RB1CC1, NSMCE2, CGRRF1, TSG101, TIPIN, NUSAP1, MIS12, ARL8B, SEPTIN10, DBF4, ZW10, BUB3, DYRK3, CDK7, MLF1, TXNL4A, NSUN2, CDC16, DLGAP5, MAPK6, CEP55, POGZ, NUP43, NEDD1, NEK1, TXNIP, DSN1, TRIM39, CDC23, ING1, USP16, USP3, CIT, NDC80, SIAH2, CDK14, GNAI2, CCNH, ANAPC15, PIN1, NPAT, CDCA2, WAPL, CCNY, SPDL1, SETDB2, HAUS4, THAP1, CCPG1, FZR1, CCNT1, VPS4B, KATNA1, RALA, RPS6KB1, MAPK4, RACK1, TP53BP2, WTAP, DAB2IP, TLK2, ENTR1, ANAPC16, SENP5, FANCD |
| cell cycle arrest | biological process | TGFB1, IFNG, TP53, INHBA, CXCL8, IL12A, CDKN2A, ATM, GAS6, PLAGL1, MTOR, RB1, KHDRBS1, SOX2, INHA, PKD1, TCF7L2, RASSF1, NBN, MYC, MSH2, PRNP, SKIL, CDKN3, SLC38A9, LAMTOR3, CAB39, CDC123, DDIT3, EIF4G2, TBRG1, CGRRF1, TSG101, CDK7, MLF1, PRR11, PPP1R9B, PRKAB1, LAMTOR5, UHMK1, TP53INP1, BTG4, MAP3K20, HBP1, JMY, BRINP2, PRKAG2, DHCR24, RRAGA, STRADB, GAS1, NOTCH1, RRAGB, APBB2, THBS1, PKD2, ZFHX3, CDKN2B, CDKN2D, IRF6, GADD45A, APC, TGFB2, CDK6, RHEB, KIF20B, GAS2L1, PPM1G, ERN1, MFN2, CDKN1B, STRADA, ABL1, CDKN2C, CAB39L, PML, TGFBR1, PPP1R15A, PPM1A, PRKAA2, KMT2E, RRAGD, CDKN1A, MAP2K6, MAPK12, LAMTOR1, BARD1, WDR6, IRF1, MAP2K1, ILK, MLST8, WNT10B, HRAS, FOXO4, CDKN1C, MTBP, GAS2, ERN2, KAT2B, TBRG4, CGREF1, RBM38, APBB1, BRINP1, VASH1, RPTOR, SGSM3, IFNW1, SMAD3, ING4 |
| cell cycle checkpoint | biological process | RB1 |
| cell cycle comprising mitosis without cytokinesis | biological process | E2F8 |
| cell cycle G2/M phase transition | biological process | AKAP8, AKAP8L |
| cell cycle phase transition | biological process | CDC7, TIPIN, UPF1, TIMELESS, PTPRC, UBE2L3 |
| cell death | biological process | HMOX1, CLU, IL17A, CIDEA, OPTN, PNPLA8, EIF4G2, SNCAIP, OLR1, ALS2, GSDME, BCL10, PMP22, MAP3K20, NUP62, RRAGA, EMP1, EMP2, CACNA1A, KLK8, SUSD6, VAPA, PTGER3, TGFB2, BNIP3, CDKN1B, FOSL2, MAP3K9, FBH1, NDOR1, FAF1, MAP3K10, P2RX7, PRKD2, PARP4, BRINP1, GZMM |
| cell death in response to hydrogen peroxide | biological process | SIGMAR1 |
| cell dedifferentiation | biological process | NCOA3, CDK6, ESRRB |
| cell development | biological process | INHBA, ERCC1, BMP7, GDF15, GDF9, BMP15, GATA4, SHH, INHA, IRX6, NKX2-2, IRX1, PHOX2B, ARID5B, PLA2G3, IRX4, MAF, IRF6, SMO, IRX2, CYB5R4, TRAF6, IRX5, LEF1, IRX3, ID2, HSF4, GJC1, FOXE3, GATA1, DCT, MKX |
| cell differentiation | biological process | AMH, PRM1, TP53, INHBA, VEGFA, SRD5A2, SOX9, SOX10, DAZ2, NR5A1, HIF1A, TSSK4, DAZ4, CATSPER1, CATSPER2, TSSK6, DAZ1, NDRG2, PRM2, FLT1, TYK2, AXL, AKT1, KDR, GSK3B, NR0B1, DLK1, SRY, BRDT, CIB1, RNF17, PLAGL1, DMRT1, SEMA7A, TNP1, BMP7, SRD5A1, CTNNB1, BAG6, PGF, HSPA2, TNP2, SEMA3A, ODF2, PIWIL2, DAZL, PIWIL1, YES1, BMP4, NANOS2, TSPY1, SLC7A5, SOHLH1, TXNDC8, DPY19L2, TEX15, DDX4, DAZ3, NPHP1, RAF1, MAK, FGF8, CDC42, MEF2A, MCL1, FOXO1, CDC20, DUSP6, TAF7L, H1FNT, STRA8, TXNDC2, NME8, SPATA9, SPATA16, DDX25, RNF114, NTRK1, INHA, FGF3, FGF9, ETV5, CREM, CATSPER4, PIWIL4, GALNTL5, HORMAD1, CATSPER3, BOLL, TDRD9, GTSF1, TCP11, TAF4B, GMCL1, MAEL, SLC26A8, ZMYND15, TP63, SOHLH2, WIPF3, FKBP6, CSF1, AGFG1, NANOS3, UTP14C, KLHL10, PIWIL3, NLRP14, SPATA25, CFAP69, ETV2, SEMA3E, GADD45B, RBL1, CCN2, RPS3A, RPS7, HNRNPU, RBL2, CAMK2B, CBX2, NR1D2, SEPTIN2, DZIP1, Dmrtc2, SIAH1, TTC21A, ARMC2, SEMA6D, TDRD7, PSMA8, M1AP, ZFPM2, EID1, KIF2A, DDX3X, KLF4, NUDT21, JAK2, NME5, ISL1, PUM1, ELF2, DPYSL2, RMDN3, TSG101, ZH |
| cell differentiation in hindbrain | biological process | PHOX2B, GATA2 |
| cell differentiation in spinal cord | biological process | NOTCH1 |
| cell differentiation involved in embryonic placenta development | biological process | STK3, STK4, EOMES, KRT19, KRT8, GCM1 |
| cell differentiation involved in kidney development | biological process | GLI3, PTCH1, GLIS2 |
| cell differentiation involved in metanephros development | biological process | LGR4 |
| cell differentiation involved in salivary gland development | biological process | CLCN2, NFIB |
| cell division | biological process | LIG4, AURKC, BIRC5, CCNB2, CDK1, CCNB1, WEE1, CDC25A, CDC25C, CIB1, NR3C1, GNAI1, BRSK2, RB1, SYCP3, CDC7, CDC20, 39326, 41153, SYCE1, RNF8, DYNLT1, KATNB1, WASL, 38231, CCNA2, CCNA1, SYCP1, HNRNPU, CENPE, ABRAXAS2, SEPTIN2, BORA, RBBP8, HAUS2, SEPTIN9, KIF2A, EVI5, CDC123, CETN2, CSNK1A1, GPSM2, NUP37, NSMCE2, TSG101, TIPIN, NUSAP1, MIS12, ARL8B, SEPTIN10, ZW10, BUB3, DYRK3, CDK7, TXNL4A, NSUN2, CDC16, CEP55, POGZ, NUP43, NEDD1, NEK1, DSN1, CDC23, USP16, CIT, NDC80, CDK14, GNAI2, ANAPC15, CDCA2, WAPL, CCNY, SPDL1, SETDB2, HAUS4, FZR1, CCNT1, VPS4B, KATNA1, RALA, ENTR1, ANAPC16, SENP5, MAPRE3, SMC3, OIP5, BUB1, BUB1B, TACC1, RECQL5, TNKS, RPS3, NCAPD3, DYNLT3, CKS1B, CETN1, KIF14, KLHL22, SPECC1L, SMC5, SPC24, CENPT, CHFR, MASTL, FAM83D, ANAPC5, ZNF207, DCTN3, HAUS5, GNAI3, MAP4, ITGB3BP, ASPM, CABLES1, CDCA3, PELO, ZWINT, ARL3, NCAPH, MAEA, USP37, BABAM1, MIS18A, PRC1, CCND1, NEK3, IST1, ARPP19, BCAR1, PPP1CB, PIK3C3, PARD3B, NCAPG, KIFC1, ZWILCH, CHMP1A, ANLN, BABAM2, RCC2, UBE2I, SGO1, SIRT2, SNX33, ZNF830 |
| cell envelope organization | biological process | TGM1, HRNR, TGM3 |
| cell fate commitment | biological process | SOX9, FGFR2, CASP3, NODAL, BMP4, PPARG, GATA4, FGF8, SHH, GATA5, HOXA2, KDM6B, HES1, WNT10A, WNT7B, GAS1, WNT4, NEUROG1, WNT9B, SOX12, NOTCH1, WNT3A, MITF, PRDM1, GATA3, MEF2C, TGFB1I1, WNT2B, WNT8B, NEUROD4, ONECUT2, NEUROD1, RBPJ, PML, SOX6, GATA2, SMAD2, HEY2, BARHL2, SPRY2, WNT11, EYA1, WNT10B, BMP2, ONECUT1, GDF7, ROR2, WNT9A, TBX19, WNT3, WNT6, WNT7A, WNT5B, GATA1, GAP43, PTF1A, WNT16 |
| cell fate determination | biological process | CTNNB1, EBF2, MCL1, CYP26B1, DSCAML1, HOXA2, GATA3, PTCH2, GATA2, NOTCH4, BARHL2, DLL1, PROX1, JAG1, PTCH1 |
| cell fate specification | biological process | SOX9, ITGB1, CTNNB1, SHH, TBX10, EOMES, NOTCH1, TBR1, PSEN1, CDON, SMO, APC, TBX5, MGA, TBX3, DHH, TBX20, TBX21, FKBP8, TBX6, APC2, IHH, TBX19, TBX2, TBX15, FOXA2 |
| cell gliding | biological process | MYO1G |
| cell growth | biological process | TGFB1, IL6, AR, BCL2, TGFB3, MTOR, TGFBR3, ITGAV, PRMT6 |
| cell growth involved in cardiac muscle cell development | biological process | GATA4, MAP2K4, ADRA1A, SORBS2, AKAP13, PDLIM5, AGT |
| cell junction assembly | biological process | ACTB, FERMT2, VASP, CAPZA1, FLNC, MYO9A, ACTG1, FBLIM1, OPHN1, ILK, LIMS2, SH3BP1, VMP1 |
| cell junction maintenance | biological process | CLDN1 |
| cell maturation | biological process | VEGFA, SOX10, AXL, FGFR1, CTNNB1, IL21, PPARG, IL15, ANGPTL8, RFX3, PTH1R, SOX18, HES1, CBFB, GDF11, GATA3, GHRHR, ASCL1, POU2F2, GATA2, BHLHA15, EPAS1, TUSC2, BTK, CCL19, ID2, RUNX2, FZD5, IHH, BFSP2, CCL21 |
| cell migration | biological process | USP9Y, TGFB1, IL12A, CDK1, FLT1, TYK2, GSK3B, GAS6, NODAL, ITGB1, FGFR1, PTEN, TGFBR3, ITGAV, SRC, NRG1, PROP1, NANOS1, ARF4, CCN2, GPC2, CORO1B, LAMC1, CXCR4, BAMBI, PALLD, NOX1, PIK3C2A, NARS1, IQGAP1, FAT1, SYDE2, TNS3, NCKAP1, BTG1, RAB1A, CD47, PTK7, RHOU, CLEC14A, PPP1R9B, PEAK1, TSPAN3, PTPRF, NCK1, ITGB5, HOXA5, TNFAIP1, TMEM18, VAV3, CORO1C, ARPC5, EFNA1, GPC5, HES1, KCTD13, DCHS1, JAM3, FAM83D, SDC2, RHBDF1, ARHGAP35, ABI2, CCDC88A, TAOK2, RHOD, NCK2, SLC9A1, S1PR1, SDC4, BCAR1, GPC6, THBS1, MDK, EMP2, CORO6, WWC1, PHB2, PIP5K1A, CD63, CD151, NFATC2, SCRIB, SRMS, NTN4, LIMA1, ITGB6, DGKZ, USP33, MYO18A, FUT8, RHOF, PRPF40A, NEDD9, AVL9, DOCK5, FSCN3, ITGB1BP1, ITGB3, ITGB4, RHOQ, APC, TGFB2, TIAM1, MEGF9, MMP14, ELMO2, SPATA13, GOLPH3, FER, VAV2, ADAM9, DEPDC1B, FMNL2, PRKCZ, DOCK1, CARMIL1, KNSTRN, ITGBL1, ITGB8, USP34, USP9X, HBEGF, ZRANB1, CD2AP, ITGB7, PIK3CG, MAPRE1, ASAP3, SIX2, EMILIN1, PODXL, PIK3C2B, VTN, ITGB2, LAMB1, LCP1, SCYL3, ELMO3, PSTPIP2, CDC42BPB, ASTN1, GPC4, PAK4, PDGFRB, CEACAM |
| cell migration in diencephalon | biological process | FOXB1 |
| cell migration in hindbrain | biological process | SEMA4C, POU4F1 |
| cell migration involved in coronary angiogenesis | biological process | PDGFRB |
| cell migration involved in coronary vasculogenesis | biological process | TBX5 |
| cell migration involved in endocardial cushion formation | biological process | DCHS1, NOTCH1, ENG |
| cell migration involved in gastrulation | biological process | NODAL, CER1, AMOT, MIXL1, MEGF8, LRP5, GPC3, RIC8A |
| cell migration involved in heart development | biological process | BVES, NDRG4 |
| cell migration involved in kidney development | biological process | VANGL2 |
| cell migration involved in mesendoderm migration | biological process | FGF8 |
| cell migration involved in sprouting angiogenesis | biological process | VEGFA, KDR, ITGB1, TDGF1, CLEC14A, GPLD1, ADTRP, EGR3, PIK3R3, MIA3, SRF, EFNB2, FGF2, NRP1, NR4A1, EPHB4, SLIT2, ROBO1, GREM1 |
| cell migration involved in vasculogenesis | biological process | RTN4, PDGFRB |
| cell morphogenesis | biological process | EGFR, BCL2, VDR, DMRT1, CLU, HGF, NRG1, MAEL, MAPK14, KLHL10, WDR19, SHROOM3, CSNK1A1, CDH7, NCKAP1, BCL6, STK4, ASXL1, AP3B1, SCFD1, EPHB2, CDH10, EPB42, SART3, STRADB, CDH19, LIPA, SS18, TBCC, TFCP2L1, GATA3, MSX1, CYFIP2, CDH12, FRY, TGFB2, CDH17, ARHGEF28, THOC2, CERT1, ECT2, IL7R, CYFIP1, SIDT2, ARHGEF2, SOX6, YAP1, CAPZB, LRATD1, CDH6, P2RX7, TBCCD1, LST1, PTPRO, PDPN, CDH9, CDH5, ADD1, NCKAP1L, CDH8, CDH11, CDH13, SSH1, SLC39A3, VHL, GP1BA, CDH3, CDH4, CDH15, ADAM8, KLF2, SHROOM2, CAP2, WNT3, CDH24, CDH23, UPK3A, CDHR3, CDH26, RP2, CAP1, GREM1, FRYL, PSMB10 |
| cell morphogenesis involved in differentiation | biological process | CTNNB1, DKK1, EPB41L5, LAMC3, MYH9, RELN |
| cell morphogenesis involved in neuron differentiation | biological process | RB1, HES1, UNK, SLC1A3, MEF2C, FOXG1, MYCBP2, OPHN1, ID2, TBCD |
| cell motility | biological process | DSTN, ENPP2, PLD1, PTK2, CD34, CTTN, SRPX2, IER2, CFL2, SKI, DST, PHACTR1, ETS1, ITGB4, MMP14, RAC1, ELMO2, TGFBR1, LRATD1, MAP2K1, ELMO3, PLD2, EPHA2, GAS8, IGSF8, ENG, FSCN1, ELMO1 |
| cell motility in response to calcium ion | biological process | SPAG16 |
| cell motility involved in cerebral cortex radial glia guided migration | biological process | DAB2IP |
| cell projection assembly | biological process | QRICH2, NCKAP1, SCIN, RHOU, NEFH, VAV3, RHOG, CYFIP2, PDGFA, RHOQ, RAC1, RAC2, VAV2, CYFIP1, PARVG, PARVB, PARVA, CAPG, NCKAP1L, RAC3, RHOJ, RHOV |
| cell projection morphogenesis | biological process | PACSIN2, CSPG5, NES |
| cell projection organization | biological process | AKT1, MTOR, AKAP4, NPHP1, DNAH9, CCDC103, SPAG16, DYNC2H1, TEKT4, TEKT2, KIF3A, DNAI1, PTPDC1, OFD1, RO60, IFT88, PCM1, E2F5, ARMC4, CFAP65, WDR19, TXNDC15, CEP20, CCDC113, KIF17, ATP6V1D, ACTR3, E2F4, JHY, FOXJ1, IFT74, CEP19, BBS2, FHDC1, STK36, CCP110, DEUP1, TTC30A, TMEM17, TRAF3IP1, TCTN2, NEK1, IFT52, TOGARAM1, NUBP1, TCTN1, KIF24, TCTN3, BBS5, CEP41, PDCL, DYNC2LI1, RPGR, ENTR1, UBXN10, CPLANE1, SNX10, OCRL, AHI1, DNAAF3, CPLANE2, PTPN23, INTU, B9D1, PLEK, CIBAR2, TSC1, WDR35, WRAP73, BBS9, CCDC88A, IQUB, WDR90, CEP131, CCDC66, CEP43, RP1, TTC8, ARL6, PLA2G3, SNAP29, BBS4, DCDC2, SDCCAG8, P2RY12, CBY1, FAM92A, PKN2, TTBK2, CEP89, GPR22, CFAP126, TMEM107, SAXO1, DNAI2, C2CD3, CEP162, TAPT1, CEP97, MACIR, CEP164, CFAP206, IFT43, KIAA0586, FAM161A, TMEM67, WDR60, HYLS1, CEP126, SSX2IP, NUBP2, WTIP, BBIP1, CFAP221, POC1B, CLUAP1, CEP290, KIF27, CCDC13, CFAP46, PIFO, TCHP, PARVA, CFAP410, ATP6V0D1, CILK1, ILK, KCTD17, CEP250, IFT122, TWF2, AK7, PRICKLE3, EHD3, RAB8A, ARMC9, FUZ, RAB34, TMEM138, CCNO, MYO7A, |
| cell proliferation | biological process | EGFR, TGFB1, TP53, CYP1A1, AR, BCL2, KITLG, LIG4, BRCA2, BAX, BAK1, ERBB2, ERCC1, ERCC2, CDC25A, CDC25C, AKT1, GAS6, PRL, IL1A, GPX1, EDNRA, CTNNB1, STAT3, IFNAR2, PTEN, BAD, IL2RA, IGF1, SRC, MIF, HGF, TSPY1, NRG1, KHDRBS1, PDXK, RAF1, PCNA, CDK9, SHH, PROK2, USP8, PRDX1, TCF7L2, NBN, MAS1, CSF1, NOX5, MYH10, USP13, MORF4L1, CD74, XRCC5, ANXA7, TXNRD1, GNAI2, SMAD4, MAP4K1, LTK, PPARD, TBCK, GNL3, BUB1, TACC1, ZNF324, CKS1B, USP28, FAM83D, LIPG, GNB1, CUL1, FAM83B, CSPG4, RHBDF1, CDK5RAP3, TACC2, LIPA, ASCC3, ECD, WNT3A, PPP1R8, CEP120, RASGRP4, SH2D2A, EMP2, COPS2, YY1AP1, IL18RAP, SCRIB, DDX41, TYR, GLUL, ITGA2, MKI67, MRE11, MELK, DPH1, SDCBP2, TACC3, SOX11, MRPS27, UBE2L3, LRP2, YME1L1, CERT1, ZPR1, GNG2, RAC1, USPL1, CEMP1, RRN3, FER, YPEL5, PDK1, FOXC2, PDS5B, PAX1, TGFBI, LARP1, POC1B, DACH1, IRF2, YAP1, ZFP36L1, CITED2, PAK1IP1, HOXB4, CDK3, SIX2, TBX20, E2F8, MCM7, DLX5, OCA2, BCL2L1, LRP1, FBXW8, ALKBH3, AXIN2, PES1, FPGS, ENPEP, BRAT1, NELFB, KAT2A, FOXC1, OGFOD1, CKS2, PURB, PAK5, CSF1R, RASGRF1, |
| cell proliferation in bone marrow | biological process | ACE |
| cell proliferation in forebrain | biological process | ZEB2, FGF8, KIF14, DISC1, WNT3A, EMX2, SIX3, RRM1, FABP7, LHX5, ARX, WNT7A, DIXDC1 |
| cell proliferation in hindbrain | biological process | C5AR1 |
| cell proliferation in midbrain | biological process | RYK, WNT3A, FZD3, FZD6 |
| cell proliferation involved in heart valve development | biological process | TWIST1 |
| cell proliferation involved in kidney development | biological process | GPC3 |
| cell proliferation involved in metanephros development | biological process | GPC3, PTCH1 |
| cell proliferation involved in outflow tract morphogenesis | biological process | HAND2, PITX2 |
| cell recognition | biological process | CLEC7A, CD226, NCR3, CNTNAP3, CRTAM, PECAM1, CD5 |
| cell redox homeostasis | biological process | IL6, NOS3, NFE2L2, GSR, GPX1, PRDX4, LTF, PDIA3, NOS2, TXNDC8, APEX1, TXNDC2, NME8, TXNDC12, SELENOS, DDIT3, DNAJC10, TXNRD1, CYBB, P4HB, NME9, GCLC, PDIA6, GLRX2, NQO1, HVCN1, PDIA4, PRDX6, NNT, SLC2A10, CYBA, SELENOT, ERO1A, TMX1, TXNL1, NCF1, PRDX3, TMX4, KRIT1, RAC2, PRDX5, ERP44, ERO1B, SLC11A1, TXNDC5, MPO, NFE2L1, NCF4, EGLN2, GLRX, PDIA5, TXN2, PDIA2, TXNRD2, TMX3 |
| cell surface bile acid receptor signaling pathway | biological process | GPBAR1 |
| cell surface pattern recognition receptor signaling pathway | biological process | FCN1 |
| cell surface receptor signaling pathway | biological process | EGFR, IFNG, INHBA, TNFRSF1A, TNFRSF1B, TNFSF10, ERBB2, CASP8, PRL, PRLR, LEPR, IFNAR2, IL2RA, CD79A, MIF, GFRA1, KHDRBS1, IL17A, PROKR2, CD9, OXTR, CCR5, INHA, CD8A, MAPK14, TNFRSF25, SIRPB1, CSNK1A1, FZD9, GP1BB, CCR1, ADGRL1, BDKRB2, CD79B, ADGRA2, RTN4R, FZD8, FZD4, CYSLTR1, LY96, IL1R1, PTH1R, CALCRL, MYD88, NUP62, CTF1, ANXA1, CD59, KLRC1, SYK, IL17C, C5, ITPKB, IFNGR2, FZD2, TNFRSF10D, TNFRSF10B, ASGR2, FCGR2B, GEM, IL13RA1, IRF9, MKNK2, FZD3, CD274, CLEC2D, ADRB2, FCER1A, CD86, FADD, SPRYD3, MARCO, TRPA1, GIPR, TIRAP, GHRHR, ATP1A4, DTX1, FZD7, PTPRC, CXCR2, GCGR, LY6E, ADGRF1, ADGRA3, ADGRF4, FCRL2, MCHR1, SMO, CELSR2, CELSR1, CLEC1B, CD3E, EDNRB, LIFR, COL4A3, BIRC2, C17orf99, FCRL4, ADGRB3, IGSF6, CD3G, GLP1R, CD247, CDA, EVL, GPR182, ADGRL2, TDP2, TSPAN12, SAG, IFITM1, IL7R, CBL, ADGRV1, MAGI1, ADAP1, PRKCZ, GPR157, BRD8, FCGR3B, PDCD1LG2, SEMA6A, ADGRB2, CD2, EPHA1, CRHR1, CXCR3, CRHR2, CASP10, TNFRSF14, P2RX7, PRMT1, ADGRE3, NPR1, P2RY1, PTH2R, PIP4K2B, CD101, BAG1, ADGRB1, GLP2R, CD4, FCGR2A, CX |
| cell surface receptor signaling pathway involved in cell-cell signaling | biological process | ITGAM, P2RX7 |
| cell volume homeostasis | biological process | CLNS1A, WNK3, E2F4, SLC12A2, GNB3, KCNN4, SLC12A6, SLC12A4, P2RX7, AQP1, SLC12A9, SLC12A7, ADD1, SLC12A5, CLCN6, SLC12A3, SLC12A8 |
| cell wall disruption in other organism | biological process | REG3A, REG1B, REG3G |
| cell wall macromolecule catabolic process | biological process | SPACA3 |
| cell-cell adhesion | biological process | FLRT3, CCN1, BAIAP2L1, BAIAP2, FAT1, CDH7, VCAM1, SHC1, CTNNA3, MPZL2, DLG5, KIRREL1, CD93, CD58, CNN3, DCHS1, JAM3, CDH10, CTNND1, ANXA1, CD34, CDH19, PDLIM1, ARVCF, CTNNA2, STXBP6, NLGN2, LRRC1, VEZT, SRPX2, NEGR1, FAT3, ANXA9, NTN1, KRT18, SCRIB, NRCAM, PKP4, TLN2, LRP6, PSEN1, RAPGEF1, CYFIP2, CELSR2, CELSR1, DSP, CDH12, DSG1, ROPN1B, CDC42EP1, CDH17, DLG1, TENM2, ELMO2, CTNND2, CSTA, CXADR, ADGRV1, F11R, CBLL1, FBLIM1, LPP, PDLIM5, TMOD3, CD2AP, CD2, CDH6, DLG4, DSC3, ESAM, PKP2, VNN1, ITGB2, COL8A2, DSG2, NECTIN1, PDPN, DLG3, CDH9, ASTN1, PAK4, SRF, CD33, CDH5, CDH8, CDH11, CDH13, DSC2, ICAM5, JUP, ICAM3, FOXF1, TRIM29, TTYH1, THY1, PKHD1, PECAM1, DSG3, MYH9, JAM2, LAMA3, LAMA5, CDH3, CDH4, CDH15, ADAM8, COL16A1, COL19A1, PKP3, TLN1, PIP5K1C, ITGAL, LIMS2, CDHR2, CELSR3, FAT2, COL13A1, DSG4, CDH24, SIGLEC1, ZAN, DLG2, CDHR3, CDH26, CDH22, SYNJ2BP, ICAM4, VMP1, ITGA8, KIRREL2, FNDC3A |
| cell-cell adhesion in response to extracellular stimulus | biological process | VCAM1 |
| cell-cell adhesion involved in gastrulation | biological process | RIC8A |
| cell-cell adhesion mediated by cadherin | biological process | CDH7, CDH10, CTNND1, CDH19, CDH12, CDH17, FER, CDH6, CDH9, CDH5, CDH8, CDH11, CDH13, CDH3, CDH4, CDH15, CDHR2, CDH24, CDH23, CDHR3, CDH26, AFDN |
| cell-cell adhesion mediated by integrin | biological process | ITGB1, ITGA5, ADAM9, PLPP3 |
| cell-cell adhesion via plasma-membrane adhesion molecules | biological process | CDH7, EPCAM, MPZ, DCHS1, CDH10, CDH19, ITGAM, CDH12, CDH17, UNC5D, CDH6, ITGB2, CDH9, CEACAM1, CDH5, CDH8, CDH11, CDH13, PECAM1, MAG, CDH3, CDH4, CDH15, CDH24, CDH23, CDHR3, CDH26, ADGRL3, CDH22 |
| cell-cell fusion | biological process | VASH2 |
| cell-cell junction assembly | biological process | TJP1, CDH7, CLDN5, CDH10, CTNND1, CDH19, ARVCF, AMOT, PKP4, TLN2, CDH12, DSG1, CDH17, NR1H4, CTNND2, HDAC7, FLCN, PARD6B, CDH6, PKP2, CDH9, CDH5, CDH8, CDH11, CDH13, GJA4, CDH3, CDH4, CDH15, LIM2, PKP3, TLN1, FSCN1, CDH24, CDH23, CDHR3, CDH26, GJC1 |
| cell-cell junction maintenance | biological process | NLGN2, MYADM, PARD6A, PRTN3, CSF1R |
| cell-cell junction organization | biological process | TGFB1, TGFB3, GJA1, NF2, CLDN6, TJP1, NLGN4X, MARVELD3, CLDN9, AJM1, TGFB2, XIRP2, CXADR, SDK2, CCM2, CLDN1, LIMS2, SDK1, SMAD3 |
| cell-cell recognition | biological process | ST6GALNAC6, CD209, FUT3, PCDHA7 |
| cell-cell signaling | biological process | CGA, LHB, IL1B, AMH, PGR, INHBA, AR, IL11, IL10, BDNF, SRD5A2, ADM, TNFSF10, INSL3, NR5A1, IL18, ESR2, FGFR2, FGFR3, FASLG, GNRH1, TRH, PGF, GDF15, CCL5, IL2, IL17A, FGF17, NGF, GJA1, GATA4, CCR5, SHH, INHA, FGF3, FGF9, SIRPG, S100A9, TAC1, CCL16, IAPP, AREG, FGF12, CCL20, GJC2, IL15, CCR1, CCL8, FAT1, FGFBP3, GJD2, CCN6, IL7, CXCL11, ECE2, ASIP, PANX3, CCL3, EFNA1, TNFAIP6, CTF1, LTB, GPNMB, IL17C, SIGLEC6, GRAP2, GJB1, CXCL6, FZD2, FJX1, WNT9B, PANX1, ADRB2, ADRB3, NAMPT, TEK, CCL22, GJB3, TSHB, IL3, PHEX, PKP4, GJB5, ADRA2A, FGF5, ADRA1A, LHX1, FCRL2, EREG, PDGFA, STAB1, TBX5, FGF20, CCL26, KLF10, EFNA2, CX3CR1, CRB1, AIMP1, CCL18, BHLHA15, ASH1L, LNPEP, DHH, CCL23, CHST4, GJD4, GPR101, NMUR2, IL36G, HCN2, GJA3, FGF18, MPZL1, ITGB2, CALCA, NMB, ADRA2B, DRD3, GJA5, EFNB1, GRAP, CARTPT, SFRP2, LHX5, AVP, PTHLH, CD33, DRD1, ADRA1D, PCSK1, EFNB2, SEMA3B, TNFRSF11A, PCDH8, LALBA, IFNA2, EDN1, ADRB1, BMP2, TSHR, SSTR3, GJA4, PTGIR, SST, CCL7, ENPEP, PCDH1, FGFBP1, EFNB3, FGFBP2, FGF21, DLL1, FADS1, GJB6, CXCL14, |
| cell-cell signaling by wnt | biological process | PKD2 |
| cell-cell signaling involved in cardiac conduction | biological process | PKP2 |
| cell-cell signaling involved in mammary gland development | biological process | HOXA5, LRP5 |
| cell-cell signaling via exosome | biological process | KLF5 |
| cell-matrix adhesion | biological process | CD44, STRC, ITGB1, CTNNB1, ITGAV, ITGA4, ITGA6, FN1, PKD1, CCN2, PPFIA1, SORBS1, HPSE, FERMT2, TNN, VCAM1, HOXD3, BCL2L11, SGCE, ITGA2B, ITGB5, BCAM, JAM3, PPFIA2, COL3A1, CD34, SNED1, TSC1, FGG, FERMT1, ITGA10, MADCAM1, FBLN5, EPDR1, EMP2, CD63, ANGPTL3, FGB, ITGA2, ITGB6, LYVE1, ITGB1BP1, ECM2, ITGB3, ITGB4, TIAM1, TECTA, RAC1, ADAM9, PARVG, TIMM10B, VCL, CD96, ITGBL1, ITGB8, MUC4, ITGB7, EMILIN1, TMEM8B, LYPD3, VTN, ITGB2, ILK, SRF, NID2, EDA, FGA, COL5A3, CDK5, ITGA7, FERMT3, COL16A1, MSLN, COL19A1, ADAMTS13, COL17A1, ITGAL, ITGA3, L1CAM, THBS3, COL13A1, SIGLEC1, ADAMTS12, ITGA11, FREM1, LYPD5, ITGA8, ZYX, OTOA |
| cell-matrix adhesion involved in ameboidal cell migration | biological process | ITGA4, ITGB7 |
| cell-substrate adhesion | biological process | VWF, GAS6, ITGB1, ITGA5, ITGAV, ITGA6, PPARD, PRKX, EPHB1, ITGA2, ANGPT4, SMAD6, ANGPT1, SORBS3, ITGB3, ANGPT2, ANGPTL4, ATP1B2, TTYH1, CORO1A, FAT2, MYO1G |
| cell-substrate junction assembly | biological process | ITGA5, ITGA6, FN1, TNS1, TLN1 |
| cell-substrate junction organization | biological process | RAB8B |
| cellular aldehyde metabolic process | biological process | ADH4, ALDH9A1, AKR7A2, AKR1A1, ALDH3A2, ALDH1A1, ALDH3B1 |
| cellular amide metabolic process | biological process | CYP2C9 |
| cellular amino acid biosynthetic process | biological process | MTHFD1, MTR, MTRR, CBSL, CBS, PSAT1, GLUD1, PAH, ASNSD1, ENOPH1, FOLH1B, ASS1, ASNS, ASPA, NAT8L, PYCR2, NAALAD2, BCAT1, GPT, ALDH18A1, PSPH, APIP, GLUL, GOT1, GADL1, GPT2, RIMKLB, OAT, MRI1, ADI1, CTH, FOLH1, MTHFD2L, PHGDH, RIMKLA, PYCR1, KYAT1, PYCR3, GLS2, BCAT2, GLS, GOT2, ASL, ASPG |
| cellular amino acid catabolic process | biological process | ENOSF1 |
| cellular amino acid metabolic process | biological process | MTHFR, SLC7A5, SLC6A14, GLUD1, GLDC, PTS, GOT1L1, GLUD2, CTNS, ASNS, DDC, HGD, SDSL, PEPD, GOT1, SCLY, QDPR, PHGDH, GCAT, TAT, GLS2, GOT2, GGT1, SDS, SRR, CAD, ASPG |
| cellular aromatic compound metabolic process | biological process | CYP1A2, CYP1B1, CYP4B1, SQLE, EPHX1 |
| cellular biogenic amine metabolic process | biological process | MECP2, SULT1B1 |
| cellular biosynthetic process | biological process | PRPS2, PRPS1L1, PRPS1, MRI1 |
| cellular cadmium ion homeostasis | biological process | SLC39A8, SLC11A1 |
| cellular calcium ion homeostasis | biological process | TGFB1, APOE, BCL2, VDR, ITGB1, HEXB, CCL5, EPHX2, ELANE, DMPK, ATP2A2, RMDN3, ANXA7, CCR1, CCL8, RGN, NPTN, GRIN1, TMEM165, VAPB, CCL1, PTH1R, CCL14, SLC24A5, SLC24A4, CCL3, TRDN, RYR1, CCL11, RYR2, CHERP, ATP13A2, GCM2, ATP2C1, STOML2, PKD2, HERPUD1, ATF4, CHRNA7, PSEN1, SLC8A3, PRKCB, STIM2, STC2, ANK2, SLC30A1, PLN, CSRP3, ATP13A3, SLC8A1, SYPL2, ATP2B3, ATP13A5, CCL23, TPCN2, ATP2A3, CCL19, SLC24A3, CALCA, ATP1B1, TPT1, HTR2C, DRD3, KEL, CDH5, CALCB, ATP2B1, CCL7, PKHD1, TCIRG1, ATP13A4, ATP2A1, DRD2, GPR12, ATP2B2, ATP13A1, ATP2C2, CD40, CALR, CXCL12, SLC8B1, SV2A, SLC8A2, EDN3, SLC10A7, GRIK2, DRD4, STIM1, SLC24A1, HTR2B, CAV1, CCL15 |
| cellular carbohydrate catabolic process | biological process | ENOSF1 |
| cellular carbohydrate metabolic process | biological process | GLB1, TKFC, RPE |
| cellular cation homeostasis | biological process | ATP13A2, SLC4A11 |
| cellular chemical homeostasis | biological process | WDTC1 |
| cellular chloride ion homeostasis | biological process | FASLG, SLC12A2, CKB, SLC12A5 |
| cellular component disassembly involved in execution phase of apoptosis | biological process | CASP6, CASP3, CASP8, DNM1L, BOK, CAPN10 |
| cellular component maintenance | biological process | MYOCD |
| cellular component organization | biological process | DIAPH2, INF2, DIAPH1, FMNL2, DAAM2, FMNL1, DIAPH3, FMNL3 |
| cellular copper ion homeostasis | biological process | APP, PRNP, SLC31A2, SCO1, ARF1, ATP7B, ATOX1, ATP7A, MT2A, CCDC22, SLC31A1, SCO2 |
| cellular defense response | biological process | IL4, ITGB1, HLA-G, CCR5, LGALS3BP, PRF1, BCL10, LY96, MNDA, VEZF1, GNLY, NCR1, ITK, KLRC2, RELA, CD300C, DCDC2, UMOD, KLRC3, CXCR2, CCR6, RAB23, NCF1, KIR3DL2, TYROBP, BECN1, CX3CR1, FCMR, LSP1, KLRG1, SPN, CLEC5A, TCIRG1, ADORA2B, PNLIPRP2, IL1RL2, ZNF148, LBP, ADORA2A, CCR3, PTK2B, TRAT1, C5AR1 |
| cellular detoxification | biological process | ABCG2 |
| cellular detoxification of aldehyde | biological process | AKR1A1, AKR1B10, RDH11, RDH12 |
| cellular detoxification of nitrogen compound | biological process | GSTM1 |
| cellular developmental process | biological process | PRDM1 |
| cellular extravasation | biological process | TNF, ITGB2, AZU1, JAM2 |
| cellular glucose homeostasis | biological process | RAF1, FOXO1, PIK3R1, PPARGC1A, HKDC1, NR1H4, FOXK2, STXBP3, HK2, NR1D1, CARTPT, NGFR, PIK3R2, GCK, HK3, FOXK1 |
| cellular glucuronidation | biological process | UGT2B7, UGT1A8, ABHD10, UGT1A4, UGT2B15, UGT2B4, UGT2A3, UGT2B17, UGT2A1, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| cellular heat acclimation | biological process | HSPA1A, HSPA1B, RBBP7, HSBP1, HSPA6 |
| cellular homeostasis | biological process | MCL1, TNS2, DEDD2, ABCA12, SLC22A12, FBXO4, RHOT2, RHOT1, AQP1, NFE2L1, MUC17, CCL2 |
| cellular hyperosmotic response | biological process | YBX3, ERRFI1, RCSD1, ARHGEF2, AQP1, EPO, MAPK10 |
| cellular hyperosmotic salinity response | biological process | AKR1B1, XRCC5, XRCC6 |
| cellular hypotonic response | biological process | CAB39, SLC12A6, OXSR1, MYLK |
| cellular hypotonic salinity response | biological process | SLC12A6 |
| cellular ion homeostasis | biological process | SLC12A5, RHCG, P2RY2, SLC4A1, RHAG |
| cellular iron ion homeostasis | biological process | SOD1, HIF1A, HMOX1, TF, HFE, MYC, ATP6V1G1, FXN, FTL, SKP1, NCOA4, FBXL5, NUBP1, SMAD4, FLVCR1, TFRC, FTH1, IREB2, CUL1, ATP13A2, ATP6V1A, HJV, GLRX3, NEDD8, TMEM199, FTMT, TTC7A, HMOX2, HEPH, CAND1, CCDC115, NDFIP1, ISCU, EGLN1, BMP6, SLC11A1, ATP6V0D1, SLC22A17, ABCB6, SLC40A1, TFR2, HAMP, ATP6AP1, SCARA5, ACO1, HEPHL1, TMPRSS6, FTHL17, GDF2, CYBRD1, ABCG2, ABCB7, BOLA2 |
| cellular ketone body metabolic process | biological process | OXCT1 |
| cellular ketone metabolic process | biological process | CYP2B6, NMT1 |
| cellular lactam catabolic process | biological process | DPEP1 |
| cellular lipid catabolic process | biological process | SIRT2, ACADL, MT3, LRP1 |
| cellular lipid metabolic process | biological process | NCOA2, SIN3A, LTA4H, SCAP, ANGPTL8, ZMPSTE24, STAR, GNPAT, LPIN1, ABHD2, FAM135B, ABHD1, GPAM, LPIN2, FAM135A, LPIN3, NR1H2 |
| cellular localization | biological process | MYO1D |
| cellular macromolecule biosynthetic process | biological process | EIF4G2 |
| cellular macromolecule catabolic process | biological process | PPT1, CLN6 |
| cellular magnesium ion homeostasis | biological process | SLC41A1, KEL, EDN3 |
| cellular manganese ion homeostasis | biological process | ATP2C1, SLC39A8 |
| cellular metabolic process | biological process | MTR, EXOSC10, EIF2B1, WNT7B, POLR2D, FTCD, MRI1, EIF2B2, BLM, CRCP, EIF2B4 |
| cellular metal ion homeostasis | biological process | CLDN16, LETM2, MT3, LETM1 |
| cellular modified amino acid metabolic process | biological process | KYAT1 |
| cellular nitrogen compound metabolic process | biological process | LIPT1, GRHPR, GNMT, LIAS, AGXT, DDO, HAO1 |
| cellular oligosaccharide catabolic process | biological process | NEU2 |
| cellular organofluorine metabolic process | biological process | POR |
| cellular oxidant detoxification | biological process | APOE, PTGS1, PTGS2, GSR, ALB, GPX1, MGST1, GSTT1, GPX4, PRDX4, PARK7, GSTK1, CAT, LPO, TXNDC2, S100A9, ALOX5AP, IPCEF1, SELENOS, TXNRD1, MGST3, MGST2, TP53INP1, UBIAD1, TPO, HBG2, PXDNL, GSTA1, PRDX6, NNT, PRXL2B, EPX, SELENOT, GSTO1, GPX3, HBD, HBB, GSTO2, HBZ, PRDX3, KDM3B, PRXL2A, LOXHD1, GSTZ1, GPX2, PRDX5, SELENOW, NXN, LTC4S, DUOX2, HP, HBQ1, TXNDC17, PXDN, GPX7, SESN2, HBA1, DUOX1, CYGB, TXNRD2, IYD, APOM, SRXN1 |
| cellular phosphate ion homeostasis | biological process | SLC9A3R1, GCM2, FGF23, ENPP1, SLC34A3, XPR1, SLC34A1 |
| cellular pigment accumulation | biological process | SHROOM3, SHROOM2 |
| cellular pigmentation | biological process | POMC |
| cellular polysaccharide biosynthetic process | biological process | EXT1, EXT2, FUT9 |
| cellular potassium ion homeostasis | biological process | SLC12A2, ATP1A4, KCTD7, ATP1A3, ATP1A2, ATP1B1, KCNJ2, ATP1A1, ATP1B2, ATP4A, ATP1B3, KCNMA1, ATP4B |
| cellular potassium ion transport | biological process | KCNK9 |
| cellular process | biological process | APP, GNAO1, CTNNB1, CDHR1, HDGF, RRAS2, TUBB, JUNB, PSRC1, FMNL1, MAP1B |
| cellular process regulating host cell cycle in response to virus | biological process | BAD |
| cellular protein catabolic process | biological process | APOB, PPT1, SIAH2, MAGEA2, UBE2G1, DAB2IP, HTRA2, PRKN, IDE, MAGEC2, UBE4B, DENND3 |
| cellular protein complex assembly | biological process | MBD2, CSNK2B, CCL5 |
| cellular protein complex disassembly | biological process | NRG1 |
| cellular protein complex localization | biological process | EZR, WASL, WASHC5, SNAPIN, MIOS, NACC2, SEH1L, DLG1, SGCD |
| cellular protein localization | biological process | TP53, CTNNB1, CDC42, SIN3A, SEPTIN2, OPTN, LAMTOR3, SEPTIN9, FOXJ1, FRMD6, SEPTIN10, PRPF19, DMD, AP1AR, CTNNA1, SLC9A3R1, AHI1, CPLANE2, RRAGA, AJUBA, DISC1, WNT3A, AMOT, RRAGB, CD63, ANK2, NIPBL, ID4, DVL2, ARMCX3, LATS1, CRB1, PRKCZ, EXOC8, SCYL1, RRAGD, DUOXA2, LAMTOR1, ESAM, SEPTIN11, SCYL3, GRID2, SEPTIN1, SEPTIN5, AKAP11, AXIN2, GAS8, RAP2A, DUOXA1, KCNA1, MYO7A, SEPTIN8, TMEM250, ITSN1, SPTBN4, PADI6, SEPTIN14, ZDHHC18, LRRK2, SEPTIN3, SEPTIN7 |
| cellular protein metabolic process | biological process | MMP2, IGFALS, IGF2, PRL, APP, KLK3, HEXB, LYZ, B2M, LTF, SEMG1, IGF1, SAA1, HIST1H4A, CECR1, CCN1, LTA4H, IAPP, SIAH1, CALU, LAMC1, SNCAIP, CSF2RB, LTBP1, SIAH2, RCN1, D2HGDH, APH1B, PSENEN, PROC, P4HB, IGFBP1, HSP90B1, ITIH2, FBN1, SNCA, RPS27A, KTN1, SPP1, TTF1, APH1A, EVA1A, MGAT4A, PRKN, SDC2, MBTPS1, PDIA6, FGG, GOLM1, LMCD1, QSOX1, APLP2, MFGE8, FSTL1, FGF23, FSTL3, CALB1, PAPPA2, DMBT1, SFTPB, CTSG, CKAP4, IGFBP7, FAM20C, GGA3, ODAM, MEN1, PSEN1, SCG3, AMBN, STC2, PRSS23, APOA1, PRKCSH, IGFBP4, FUCA2, TGOLN2, UBC, TNC, DNAJC3, TGFBI, MIA3, ZDHHC2, UBE2L6, TSPAN15, UBA52, HSPG2, SORL1, USP9X, CCDC59, SCG2, APOA5, CALCA, LAMB1, IGFBP2, MMP13, L2HGDH, NAT8, GGA2, GGA1, PLG, SFTPD, BPIFB2, MATN3, FGA, GIGYF2, TSPAN14, VGF, APCS, SFTPC, HRC, BACE1, TMEM132A, SERPINA10, CHGB, FURIN, UBB, IGFBP5, ADORA2B, GPC3, H3C1, MSLN, ABCA3, F2, INS, MELTF, CTSH, NUCB1, NOTUM, SHISA5, PCSK9, PGA5, ADORA2A, SLC34A1, VWA1, ANO8, NAPSA, TSPAN5, AHSG, IGFBP6, H3-3A, SPP2, SPARCL1, APOL1, SERPINA1, PENK, H4-16, H3C13, MXRA8 |
| cellular protein modification process | biological process | PLOD1, AKT1, YES1, PLAT, MAN2B1, PCMT1, UBE2D3, SLC35A1, FBXO11, NTAQ1, TSG101, LIPT1, SERP1, SEPHS1, MSRA, GNMT, RPN2, UBE2N, RABGGTB, PIGH, STK38, TTLL7, FBXO2, LOXL2, TTLL1, RPN1, TGM1, UBA7, CDKL3, TGM5, MMP15, PLOD2, UBE2I, NEDD8, ERO1A, MANBA, ADPRH, PHEX, CHRM3, ST8SIA2, ST8SIA4, TTLL6, TTL, TTLL2, LOX, UBE2L3, TTLL4, PCMTD1, PPP4R2, LCMT1, RIMKLB, PRKDC, FBXO22, TTLL11, UBA3, FBXW2, WWP2, ABL1, TTLL9, ATG3, CDC34, USP25, UBE2L6, ABL2, UBA52, QPCT, UBL5, PCMTD2, UBA6, PHKA2, TTLL12, RIMKLA, MCRS1, RIPK3, CPE, UBE2M, NAGPA, UBL4A, FBXL2, PARP4, PADI4, HLCS, ST3GAL6, AKT2, TTLL10, TTLL3, USP6, TGM3, ST3GAL1, BAP1, SAE1, UBE2S |
| cellular protein-containing complex assembly | biological process | HACD1, DMD, ATF1, DNAJB12, FGG, RIC3, SAMM50, USH1C, AP2M1, AXIN1, FGB, TIAM1, DNAJB14, PDE4DIP, TAF10, FGA, LONP1, TRAF2 |
| cellular respiration | biological process | BAX, CYP1A2, CYCS, COX10, LYRM7, NDUFAF2, COQ10B, SLC25A13, NDUFS4, PPARGC1A, NDUFS1, NFATC4, NR4A3, SLC25A25 |
| cellular response to 1-oleoyl-sn-glycerol 3-phosphate | biological process | LPAR1 |
| cellular response to 2,3,7,8-tetrachlorodibenzodioxine | biological process | PDE2A |
| cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine | biological process | PTAFR |
| cellular response to 3,3',5-triiodo-L-thyronine | biological process | SIX1 |
| cellular response to acetylcholine | biological process | ROCK2 |
| cellular response to acidic pH | biological process | RAB11FIP5, SLC9A1, PKD2L1, RAB11B, CHP1, AQP10, IMPACT, TRPV1 |
| cellular response to actinomycin D | biological process | RPL23, TP53 |
| cellular response to aldosterone | biological process | AIFM1 |
| cellular response to alkaline pH | biological process | KCNK4, INSRR |
| cellular response to alkaloid | biological process | ICAM1, MDM2, STAR, DDC, BCL2L1, TH, HTR1B, TRPV1 |
| cellular response to alkyl hydroperoxide | biological process | CCL5 |
| cellular response to amine stimulus | biological process | ASS1, UROS |
| cellular response to amino acid starvation | biological process | ATF3, DAP, MAP1LC3A, SESN3, SH3GLB1, NPRL2, PRKD1, MIOS, RRAGA, GCN1, DEPDC5, RRAGB, ATF4, SEH1L, SLC38A2, LARS1, C12orf66, EIF2S1, MAP3K5, BMT2, SZT2, FLCN, CDKN1A, ITFG2, EIF2AK2, NPRL3, SESN2, RNF152, TFEB, WDR24, IMPACT, KPTN, WDR59, EIF2AK3 |
| cellular response to amino acid stimulus | biological process | EGFR, TNF, MMP2, DNMT1, NSMF, CCL5, SLC38A9, LAMTOR3, COL5A2, SH3BP4, SESN3, CAPN2, HNRNPD, LAMTOR5, XBP1, NEURL1, PDGFD, ASS1, COL3A1, COL4A1, RRAGA, SOCS1, RRAGB, IPO5, CYBA, NTRK2, CPEB4, LARS1, CPEB1, COL1A2, COL6A1, ZEB1, ATP7A, CPEB3, RRAGD, LAMTOR1, GLRA1, BCL2L1, PDGFC, PDGFRA, SESN2, COL16A1, RPTOR, GLRA2 |
| cellular response to ammonia | biological process | CPS1 |
| cellular response to ammonium ion | biological process | ASS1, KCNC2 |
| cellular response to angiotensin | biological process | ARID1B, CYBA, RELA, SLC30A10, CDC6, PRKCD, BRIP1, AGT |
| cellular response to anisomycin | biological process | MAPK13 |
| cellular response to anoxia | biological process | EEF2K |
| cellular response to antibiotic | biological process | IL1B, CYP17A1, MDM2, HSPA5, STAR, SLC9A1, CRIP1, CDKN1B, PLA2G4A, ATP7A |
| cellular response to arsenic-containing substance | biological process | HMOX1, DDX3X, MKNK2, GSTO1, ZFAND2A, GSTO2, PPIF, CPEB2, UROS |
| cellular response to arsenite ion | biological process | DHX36, ZFAND1 |
| cellular response to arsenite(3-) | biological process | SLC38A2 |
| cellular response to ATP | biological process | SOD1, PTGS2, P2RY4, P2RY11, HSP90B1, P2RY12, TAF1, CIB2, P2RX7, P2RY1, SSH1, TRPM4, P2RX4, P2RY2, P2RX3, PDXP, TRPV1 |
| cellular response to azide | biological process | AOC1 |
| cellular response to bacterial lipopeptide | biological process | TLR2, TIRAP, TLR1, TLR6, CD36 |
| cellular response to benomyl | biological process | IMPACT |
| cellular response to beta-amyloid | biological process | CASP4, PRNP, SNX6, VCAM1, GRIN1, BCL2L11, LGMN, FCGR2B, ADRB2, NAMPT, CACNA1A, PSEN1, ATP1A3, EPHA4, TREM2, LRP1, FPR2, CDK5, NGFR, BACE1, CACNB1, GRIN2A, FOXO3, GRM5, TLR6, CD36, AGER |
| cellular response to bile acid | biological process | KCNMB1, NR1H4, ABCB4, HAMP, GPBAR1 |
| cellular response to bleomycin | biological process | TIMELESS, DDX11 |
| cellular response to BMP stimulus | biological process | BMP7, BMP4, BMPR2, FN1, GATA5, SMAD4, PHOX2B, CER1, ACVR1, SPINT2, BMPR1A, SPINT1, COL2A1, HJV, GATA3, TMEM100, BMP6, ACVR2A, DLX5, RUNX2, BMP2, ACVRL1, DLX1, ADAMTS7, GDF2, SMAD9, ADAMTS12, SMAD5 |
| cellular response to brain-derived neurotrophic factor stimulus | biological process | UBE3A, EEF2K, SH3GL2, EEF2, NTRK2, TMEM108, WASF1, PDPK1, EIF4A3 |
| cellular response to butyrate | biological process | CLDN1 |
| cellular response to cadmium ion | biological process | SOD1, OGG1, CYP1A2, HMOX1, AKR1C3, UBE2D3, MT1A, CYBB, STAR, MT1F, NCF1, MT1HL1, MT1G, MAPK9, MT1M, MT1H, ATP7A, MT2A, MT1E, MT1X, FOS, PPP5C, MT3, MT1B |
| cellular response to caffeine | biological process | CASQ2, RYR1, RYR2, PPARGC1A, TMEM38B, SLC8A1 |
| cellular response to calcium ion | biological process | AKR1C3, MEF2A, ALOX5AP, FUS, CAMK2D, EEF2K, IQGAP1, CPNE8, CPNE3, SYT13, CHP2, BRAF, RYR1, FOSB, NRXN1, LGMN, CAPN3, ITPKB, CLIC4, SYT1, ENDOG, CPNE2, SYT5, HPCA, MEF2C, PKD2, RASGRP2, CRHBP, CPNE9, SYT12, GUCA1A, GPLD1, CACYBP, PPIF, ADCY8, CPNE1, ECT2, SLC25A24, ADGRV1, CPNE4, JUNB, PRKAA2, ASPH, CARF, FOS, SYT17, CPNE6, ADD1, EDN1, DMTN, LCE1D, SYT6, CPNE5, SYT9, RASA4, JUND, ACER1, MCOLN1, CPNE7, SYT7, TRPM2, SCN5A, SYT2, SYT3, SYT15, SLC25A23, RASAL1, DPEP1, SYT10 |
| cellular response to caloric restriction | biological process | SIRT2 |
| cellular response to cAMP | biological process | WT1, CFTR, APP, SRD5A1, EZR, APEX1, RAP1A, SLC26A3, EEF2K, CPS1, RAPGEF2, STAR, ASS1, AQP9, ADIPOQ, FDX1, PKD2, CRHBP, SLC8A3, RAPGEF1, AKAP9, INPP5K, SLC8A1, PDE4D, ZFP36L1, PIK3CG, HCN2, AQP1, ITPR2, HCN1, WNT10B, RAPGEF3, KCNE1, DMTN, PTAFR, PDE2A, IGFBP5, HCN4, AANAT, SLC5A5, SLC26A6, RAP1B, PENK, AKAP6 |
| cellular response to camptothecin | biological process | RECQL5, BLM, SPIDR |
| cellular response to carbohydrate stimulus | biological process | PRKCB |
| cellular response to carbon monoxide | biological process | HIF1A |
| cellular response to catecholamine stimulus | biological process | GNAS, GNB1, ADCY6, GNG2, DRD1, NR4A3 |
| cellular response to cell-matrix adhesion | biological process | GSTP1, SKP2 |
| cellular response to cGMP | biological process | RAPGEF2, PDE3A, SLC6A4, HCN2, PDE2A, HCN4 |
| cellular response to chemokine | biological process | SLC12A2, ZC3H12A, SH2B3, WNK1, LOX, DOCK8, DUSP1, OXSR1, FOXC1, CXCL12, CCL21, RIPOR1, RIPOR2 |
| cellular response to cholesterol | biological process | INHBA, AACS, GRAMD1C, MLC1, CES1, HMGCS1, LRP6, SMO, GPLD1, GRAMD1A, OSBPL7, NFE2L1, DAG1, PTCH1, GRAMD1B |
| cellular response to chromate | biological process | BAD |
| cellular response to cisplatin | biological process | ADIRF, TIMELESS, SLC31A1, DDX11 |
| cellular response to cobalt ion | biological process | FAS, HIF1A, BNIP3, ATP7A, TIGAR, SERPINF1 |
| cellular response to cocaine | biological process | CCNA2, CRH, CRHBP |
| cellular response to cold | biological process | FOXO1, CIDEA, RNF34, SLC9A1, UCP1, NFKBIA, SAXO1, DNAJC3, NFE2L1, EIF2AK3 |
| cellular response to copper ion | biological process | PRNP, AQP2, MAP1LC3A, MT1A, SNCA, MT1F, MT1HL1, MT1G, MT1M, AOC1, MT1H, ATP7A, MT2A, MT1E, MT1X, MT3, AQP1, NFE2L1, MT1B, BACE1 |
| cellular response to copper ion starvation | biological process | AOC1 |
| cellular response to corticosteroid stimulus | biological process | AKR1C3 |
| cellular response to corticosterone stimulus | biological process | ATP2B1, FOXO3, NPAS4 |
| cellular response to corticotropin-releasing hormone stimulus | biological process | NR4A2, CRHR1, CRHR2, NR4A3, NR4A1 |
| cellular response to cortisol stimulus | biological process | KLF9 |
| cellular response to cyanide | biological process | HIF1A |
| cellular response to cycloheximide | biological process | KLF4, XRN1, KLF2 |
| cellular response to cytokine stimulus | biological process | FAS, STAT1, STAT3, CCL5, ITGA4, CDK9, TBK1, CXCR4, DPYSL3, PTPN23, HAX1, PTPN2, IL1F10, PTPN6, IL13, GATA3, IL18RAP, PTPN20, PID1, PTPN13, PTPN9, TRAF6, NFAT5, LEF1, HCLS1, POU4F1, CSF3, PTPN7, NLRP12, POU4F2, IL18BP, MME, CCR7, PTPN5, FOXF1, PTPN14, PTPN12, TCIRG1, PTPN18, PTPN4, IL1RL2, CSF1R, IL17RA, SIGIRR, KHSRP, SMAD3, FOXH1, ASAH2, AKAP6, TRPV1 |
| cellular response to decreased oxygen levels | biological process | AKT1, PTEN, PICK1, CPEB4 |
| cellular response to dexamethasone stimulus | biological process | TGFB1, IL6, CASP9, DNMT3B, SRD5A1, FOXO1, CBX3, FECH, METTL21C, ERRFI1, STAR, ASS1, PCK2, CRH, FBXO32, EIF4EBP1, CFLAR, EIF4E, AQP1, MSTN, SERPINF1, TFAP4 |
| cellular response to diacyl bacterial lipopeptide | biological process | TLR2, TLR6, CD36 |
| cellular response to dithiothreitol | biological process | CERS1 |
| cellular response to DNA damage stimulus | biological process | TP53, BCL2, BRCA1, LIG4, BRCA2, FMR1, BAX, OGG1, USP1, ERCC1, MGMT, ERCC2, XRCC1, XPA, MAPK3, MAPK1, AKT1, CASP3, CASP9, UBE2B, ATM, CIB1, CHD2, POLQ, PARP1, RAD23A, RAD23B, MLH1, PMS2, ATR, TEX15, XAB2, MLH3, PCNA, H2AFX, APEX1, CDK9, XPC, FOXO1, CLOCK, BRD4, RNF8, TOP2A, MAEL, PRMT6, NPAS2, TP63, RASSF1, NBN, MYC, MPG, MSH2, FOXM1, KIAA0101, MAPK14, ZBTB5, FANCA, XRCC2, UBE2D3, GTF2H3, STXBP4, SLF2, ANKLE1, HELQ, UBE2W, USP47, RBBP8, WAC, BCCIP, REV1, ZBTB47, MCM8, MCTS1, FAN1, REV3L, KIN, UBR5, DDIT3, CETN2, TRIP12, MORF4L2, EPC2, NEIL1, NSMCE2, UIMC1, TIPIN, EXO5, ASH2L, MORF4L1, POLH, SUPT16H, PHF1, ACTL6A, XRCC5, RPA2, FEN1, CDK7, CBX1, XIAP, CBX3, ZC3H12A, SWSAP1, RNF168, ZDHHC16, HMCES, ZNF385A, SLX1A, FAAP24, PARPBP, ZBTB4, PRPF19, ZNF652, USP16, USP3, PSMD14, AP5Z1, ATMIN, RAD51C, SFPQ, BCL6, PMS1, NCOA6, HUWE1, DTX3L, FBXW7, AKTIP, ZMAT3, POLE3, INTS7, FZR1, OARD1, ZMPSTE24, BCL3, ATRX, UBE2N, RBBP5, APTX, TLK2, FANCD2, AP5S1, BAZ1B, VAV3, SMC3, RECQL5, RPS3, ERCC6, RRM2B, SETX, RBBP6, SHLD2, CHD1L |
| cellular response to dopamine | biological process | GSK3B, SIN3A, HDAC2, PRKN, ATF4, ABL1, GABPA, SULT1A3, DRD1, LRRK2 |
| cellular response to drug | biological process | IL1B, TP53, HIF1A, ESR2, GAS6, NFE2L2, NOS2, CD69, RAP1A, MYC, PRNP, CXCR4, PPP1R12A, RNF149, RBM22, PPP1R14A, PPP1R9B, NKX3-1, RECQL5, KCNH2, SLAMF8, TFRC, PPP3CB, ADIPOQ, FBP1, DDC, REST, MEF2C, CRHBP, GPLD1, PDE4B, ADSS1, PPP3CA, AIM2, QDPR, MT2A, PRKAA2, MT3, EFTUD2, TH, HTR1B, PPAT, EDN1, RAP2A, UMPS, CERS1, PPM1E, FGF21, TLR3, NME1, KCNC1, PDE2A, CAD, DPEP1, CRKL, RAP1B, ANKRD1, ACER2, UCHL1, PDE4A |
| cellular response to dsDNA | biological process | RIOK3 |
| cellular response to dsRNA | biological process | RIOK3, P2RX7 |
| cellular response to electrical stimulus | biological process | HIF1A, NSMF, IGF1, ADSS2, SLC9A1, REST, HPCA, ADSS1, PALM, RPE65, GRM1 |
| cellular response to endothelin | biological process | CRK |
| cellular response to epidermal growth factor stimulus | biological process | EGFR, SOX9, AKT1, GSTP1, EEF1A1, BAIAP2, IQGAP1, MARS1, DUSP22, TDGF1, PPP1R9B, ERRFI1, STAT5B, DAB2IP, BAG4, CFLAR, SYAP1, ZPR1, ZFP36L2, INPP5K, CBL, KNSTRN, ZFP36, ZFP36L1, MCM7, DUSP3, NCL, GAREM1, PDE8A, PTPN12, FOXC1, PDPK1, CAD, VIL1 |
| cellular response to epinephrine stimulus | biological process | SRD5A1, SNCA, STAR, RYR2, ADIPOQ, SLC9A1, SIRT2, PDE4B, PDE4D, PKLR |
| cellular response to erythropoietin | biological process | GSK3B, MT2A, MT1X, CD40 |
| cellular response to estradiol stimulus | biological process | EGFR, ESR1, IL10, NRIP1, ESR2, SRD5A1, IGF1, CCNA2, HNRNPD, PPP1R9B, BCL2L11, RUVBL2, NCOA3, H2AZ1, PPARGC1A, AIFM1, CRHBP, ITGA2, CFLAR, CCDC62, KAT5, KIF18A, DDX18, POU4F1, RAMP3, POU4F2, MSX2, ZNF703, MYOD1, MYOG, SSTR3, FAM210B, GPER1 |
| cellular response to estrogen stimulus | biological process | ESR1, FAS, MDM2, TRIM24, SERPINB9, PELP1, CRHBP, SRA1, SFR1, BCAS3, ARID5A, WBP2, RARA |
| cellular response to ethanol | biological process | CCL5, SPI1, KCNMB1, CYBB, TP53INP1, ADCY7, PRKCE, GLRA1, ITPR2, CCL7, GLRA2 |
| cellular response to exogenous dsRNA | biological process | IFIH1, ZCCHC3, COLEC12, IFIT1, FLOT1, RALB, STING1, CGAS, PQBP1, MUL1, TLR3, IRF3, MAVS, CAV1 |
| cellular response to extracellular stimulus | biological process | AXL, ITGA6, AIF1, SLC1A2, ARHGAP35, ADNP, CDKN2B, PTPRC, NR4A2, LYN, FOS, CDKN1A, P2RX7, SFRP2, TLE5, ADORA2B, GSDMD, ASGR1 |
| cellular response to fatty acid | biological process | IL1B, CCNB1, E2F1, SRC, KCNK4, PDK4, PDK3, XRCC5, LPL, CPT1A, PPARGC1A, LDLR, IRS1, PID1, UCP1, NR1H4, NME2, FFAR3, SREBF1, EDN1, NME1, PTAFR, SMARCD1 |
| cellular response to fibroblast growth factor stimulus | biological process | CXCL8, CD44, CTNNB1, CCL5, KDM5B, IQGAP1, TDGF1, CPS1, STAR, GCLC, SETX, POSTN, LHX1, ITGB1BP1, ZFP36L2, EGR3, DSTYK, ZFP36, ZFP36L1, HYAL2, NR4A1, CCL2, CDC5L |
| cellular response to flavonoid | biological process | IP6K2 |
| cellular response to fluid shear stress | biological process | PTGS2, NFE2L2, SRC, PLAU, CA2, XBP1, MEF2C, PKD2, HAS2, MTSS1, HDAC3, KLF2, PTK2B |
| cellular response to folic acid | biological process | FOLR1 |
| cellular response to follicle-stimulating hormone stimulus | biological process | INHBA, STAR, GCLC, PPARGC1A, POR, NOTCH1, EFNA5, HMGCS1, EPHA8 |
| cellular response to forskolin | biological process | ADCY2, GNAI1, FDX1, EFNA5, ADCY6, ADCY8, ADCY5 |
| cellular response to fructose stimulus | biological process | SLC2A5, XBP1, PPARGC1A, SLC26A6 |
| cellular response to gamma radiation | biological process | ATM, ATR, H2AFX, XRCC5, ZMPSTE24, CRYAB, TLK2, MAP3K20, EGR1, TSPYL5, XRCC6, CYBA, ELK1, YAP1, CDKN1A, BCL2L1, HRAS, RPL26, TREX1, TMEM109, TP53, GTF2H5 |
| cellular response to glial cell derived neurotrophic factor | biological process | PITX3 |
| cellular response to glucagon stimulus | biological process | GNAS, ADCY2, PRKAR2A, CPS1, PRKACB, ASS1, GCGR, GLP1R, ADCY6, ADCY8, ADCY7, PRKACG, ADCY9, GLP2R, PRKAR2B, ADCY4, FGF21, PRKAR1B, ADCY5 |
| cellular response to glucocorticoid stimulus | biological process | AHR, GSTP1, IL17A, HNRNPU, ISL1, BCL2L11, ANXA1, REST, UBE2L3, ZFP36L2, ZFP36, ZFP36L1, SSTR4, EDN1, MYOD1, SSTR3, FAM107A, SSTR5 |
| cellular response to glucose starvation | biological process | TP53, BCL2, NFE2L2, HSPA5, PICK1, HIGD1A, HNRNPA1, SESN3, ZC3H12A, SH3GLB1, XBP1, PRKAG2, ASNS, PIK3C3, UPP1, ATF4, CPEB4, C12orf66, BECN1, IFI16, SZT2, PIK3R4, PRKAA2, BHLHA15, TBL2, MTMR3, ITFG2, SESN2, NUAK2, FOXO3, MYBBP1A, IMPACT, KPTN, EIF2AK3 |
| cellular response to glucose stimulus | biological process | IL1B, ICAM1, FAS, HIF1A, GAS6, PIK3CA, POLG, PLAU, FN1, GATA4, RAP1A, SIN3A, AACS, PDK3, XBP1, STAR, RACK1, GCLC, TRA2B, WDR35, PPARGC1A, PCK2, ENDOG, ZBTB20, OPA1, CYBA, IRS2, GHRHR, MEN1, NEUROD1, KCNB1, ERN1, ADCY8, PPP3CA, FIS1, UNC13B, GRIK5, NME2, PRKAA2, SOX4, TH, SRF, ZNF236, FGF21, GJB6, NME1, FOXO3, SERPINF1, SLC29A1, SLC39A14, GPER1, LIN28A |
| cellular response to glycoprotein | biological process | TSHR |
| cellular response to glyoxal | biological process | PARK7 |
| cellular response to gonadotropin stimulus | biological process | WT1, LHCGR, CYP17A1, NSMF, STAR, POR, PAX8, SLC5A5 |
| cellular response to gonadotropin-releasing hormone | biological process | GNRHR, ANXA5, CRHBP, GPR173, UMODL1, RAP1B |
| cellular response to granulocyte macrophage colony-stimulating factor stimulus | biological process | MAPK1, AKT1, PDE1B, ZFP36L2, ETV3, ZFP36, CD4, FCAR, PDE2A, NPR2 |
| cellular response to gravity | biological process | PTAFR |
| cellular response to growth factor stimulus | biological process | TGFB1, TNFRSF1B, BGLAP, ERBB2, AKT1, MDM2, GAS6, CIB1, CLU, SRD5A1, CTNNB1, CAT, INSR, BMP4, NTRK1, EMD, KLF4, CPNE3, SHC1, ACVR1B, PDGFB, RPS6KB1, HTR3A, STAT5B, RACK1, ACVR1, HTRA2, BMPR1A, DDC, ACVR2B, THBS1, FEZ1, EHD4, ACVR1C, URI1, LRP2, TWIST1, MAPK7, ANGPT2, TGFBR1, OPRD1, ACVR2A, TGIF1, TH, MSX2, TGFBR2, MAP2K5, TWF2, BMP2, MYOG, ACVRL1, DTYMK, PLK5, MAP1B, TRPV1 |
| cellular response to growth hormone stimulus | biological process | STAR |
| cellular response to heat | biological process | HMOX1, HSF1, IL1A, HSPA1A, HSPA1B, ATP2A2, HIKESHI, HSF5, DHX36, HDAC2, IRAK1, SLU7, CETN1, ZFAND1, HTRA2, ARPP21, BAG3, STUB1, HSFX1, THBS1, ATXN3, CLPB, HSFY1, PDCD6, YWHAE, EIF2S1, LYN, TPR, IER5, CDKN1A, ST8SIA1, SLC52A3, MYOF, TFEC, HSPA6, SCARA5, ANO1, HSF4, FGF1, NF1, CXCL10, TRPV1 |
| cellular response to heparin | biological process | SOX9, EGR1, AOC1, SLIT2 |
| cellular response to hepatocyte growth factor stimulus | biological process | IL6, IL10, GSK3B, HGF, PLAU, TDGF1, GCLC, LGMN, BCAR1, RELA, SIRT2, APPL2, APPL1, NRP1, VIL1 |
| cellular response to high density lipoprotein particle stimulus | biological process | CCL5, ABCG1 |
| cellular response to high light intensity | biological process | AKT2 |
| cellular response to histamine | biological process | GABRB1, HRH1, GABRG2, GABRB3, DIAPH1, GABRB2, AOC1, GABRA1 |
| cellular response to hormone stimulus | biological process | PLOD1, CYP11B1, STAT3, PGF, NCOA2, CYP11B2, OXTR, AIF1, SOCS2, STAT5B, NCOA3, ASNS, FOSB, UCP3, RAMP2, CCKAR, HCRTR1, ROBO2, IGFBP7, ADRA2A, UCP1, NPFFR2, GHR, NCOA1, INPP5K, JUNB, FOS, DUSP1, PROKR1, RAMP3, IGFBP2, AVPR2, AVPR1B, GPR150, PLOD3, CACNA1H, RAMP1, JUND, SLIT3, SLIT2, GNRHR |
| cellular response to hydrogen peroxide | biological process | IL6, FAS, HIF1A, CDK1, GSK3B, MDM2, EZH2, NFE2L2, F3, PARK7, APEX1, FOXO1, CYP1B1, KLF4, FXN, MAP1LC3A, HDAC2, KDM6B, RPS3, PCGF2, SETX, PDGFD, PLEKHA1, ANXA1, OSER1, NQO1, CBX8, RELA, IL18RAP, AIFM1, ETS1, SMPD3, PPIF, BNIP3, ECT2, ZNF277, ABL1, MAPK7, MAP3K5, PRKCD, PPP5C, HDAC6, AQP1, RIPK3, PDGFRB, IMPACT, KLF2, MAPK13, TRPM2, STAT6, NET1 |
| cellular response to hydrogen sulfide | biological process | PINK1 |
| cellular response to hydroperoxide | biological process | AIF1, TP53INP1, PRKD1, OXR1, PRKCD, DAPK1, CD36 |
| cellular response to hydrostatic pressure | biological process | FAS, PKD2 |
| cellular response to hydroxyurea | biological process | FMR1, ATRX, TIMELESS, RTF2, NSMCE3, BLM, DDX11, TREX1, DDI1, SPIDR |
| cellular response to hyperoxia | biological process | FAS, DNMT3B, PPARG, FOXO1, NOX1, CAV1 |
| cellular response to hypoxia | biological process | TP53, ICAM1, BCL2, VEGFA, FAS, PTGS2, HIF1A, TERT, HMOX1, CCNB1, AKT1, MDM2, E2F1, BMP7, MTOR, PTEN, BAD, SRC, PLAU, CCNA2, B3GAT1, HIGD1A, KCNMB1, RTN4, HIF3A, KCNK2, CYBB, P4HB, PTN, IRAK1, PPARD, NKX3-1, NPEPPS, SIRT4, GNB1, PPARGC1A, MDM4, BNIP3L, AK4, ACAA2, KCND2, STUB1, SLC9A1, ENDOG, OPA1, SIRT2, ERO1A, PHB2, RORA, EIF4EBP1, SLC8A3, PINK1, ANGPT4, CFLAR, GNGT1, CPEB1, STC2, BNIP3, HP1BP3, FAM162A, SCN2A, HIPK2, TWIST1, AQP3, SLC8A1, PTGIS, CPEB2, MPL, OPRD1, ATP7A, ZFP36L1, CARD16, EPAS1, EGLN1, RGCC, SUV39H2, TBL2, S100B, SLC2A4, PRKCE, HYOU1, MT3, AQP1, HILPDA, NDRG1, EGLN2, BRIP1, EDN1, UCN3, TIGAR, KCNK3, FOXO3, ADAM8, VASN, SLC29A1, FMN2, ANKRD1, NDNF |
| cellular response to increased oxygen levels | biological process | ATP6V1G1, ATP6V1A, TMEM199, CCDC115, ATP6V0D1, ATP6AP1 |
| cellular response to indole-3-methanol | biological process | BRCA1, CTNNB1, CDH1, CTNNA1, JUP |
| cellular response to inorganic substance | biological process | ADCY10, AQP1 |
| cellular response to insulin stimulus | biological process | HIF1A, AKT1, GSTP1, PARP1, SRD5A1, IGF1, INSR, SRC, PPARG, FOXO1, USF1, SELENOS, SORBS1, EEF2K, MARS1, TRIB3, EPRS1, PIK3R1, SLC25A33, ERRFI1, XBP1, RPS6KB1, STAR, C2CD5, GCLC, HDAC9, PKM, RAB31, ADIPOQ, PCK2, GHSR, RAB8B, SLC9A1, MYO5A, LPIN1, IRS2, ENPP1, GPT, IRS1, GHRHR, APRT, CFLAR, GPLD1, CPEB1, RHOQ, GOT1, WDTC1, SYAP1, TBC1D4, PRKDC, INPP5K, FER, PDE3B, DENND4C, CYFIP1, CPEB2, PRKCZ, INSIG1, PLA2G1B, ZFP36L1, LPIN2, SLC2A4, SREBF1, YWHAG, POU4F2, CEACAM1, PPAT, RAB8A, PIK3R2, OTOP1, KAT2B, CAPN10, HDAC5, PDPK1, AKT2, GCK, PCSK9, LPIN3, APOBEC1, SLC39A14, TRARG1, SRSF5, PKLR, INSIG2 |
| cellular response to insulin-like growth factor stimulus | biological process | CTNNB1, CCNA2, SLC25A33, FBN1, GHSR, SYAP1, CRK |
| cellular response to interferon-alpha | biological process | AXL, GAS6, RO60, OAS1, STAR, GATA3, IFNAR1, IFIT2, TPR, FCAR, PYHIN1, IFIT3 |
| cellular response to interferon-beta | biological process | STAT1, CAPN2, HTRA2, MNDA, DDX41, AIM2, IFI16, PNPT1, CDC34, IRGM, UBE2K, STING1, IRF1, TLR3, TREX1, PYHIN1, TRIM6 |
| cellular response to interferon-gamma | biological process | GAPDH, CCL5, NOS2, AIF1, CX3CL1, CCL16, KIF5B, CCL20, STXBP4, ACTR3, CCL8, LGALS9, EPRS1, TDGF1, CD47, STX8, SYNCRIP, CCL1, STAR, CCL14, FLNB, CCL3, CD58, RPL13A, ASS1, IL12RB1, CCL11, VPS26B, GBP5, RAB20, MRC1, KIF16B, CCL22, CDC42EP2, GBP2, CDC42EP4, VAMP3, GBP1, EVL, CCL26, HLA-DPA1, ACTG1, GBP3, STXBP3, CCL18, ACTR2, DAPK1, CCL23, CCL19, IRF8, CCL3L1, FCAR, EDN1, WAS, CCL7, STX4, MYO1C, TLR3, CLDN1, ADAMTS13, STXBP2, SLC26A6, CCL17, CCL21, CCL2, ZYX, CCL15 |
| cellular response to interleukin-1 | biological process | IL6, ICAM1, CXCL8, FAS, SOX9, HIF1A, HSPA9, CCL5, IL17A, FN1, RBMX, CX3CL1, CCL16, CCL20, AKAP12, CCL8, ZC3H12A, TFPI, CD47, MAPK11, CCL1, CCL14, DAB2IP, NKX3-1, CCL3, CCL11, FGG, CHI3L1, UPF1, RELA, HAS2, CCL22, RORA, NLRP7, FGB, GBP2, TANK, YY1, HYAL3, GBP1, RC3H1, CCL26, PTGIS, GBP3, CCL18, NR1D1, CCL23, HYAL2, CCL19, CCL3L1, PYCARD, EDN1, CCL7, USP10, ADAMTS7, KLF2, MAPK13, CD40, MYLK3, CACTIN, ADAMTS12, CCL17, CCL21, ANKRD1, CCL2, CCL15 |
| cellular response to interleukin-11 | biological process | SBNO2 |
| cellular response to interleukin-12 | biological process | CD47 |
| cellular response to interleukin-13 | biological process | SHPK |
| cellular response to interleukin-18 | biological process | IFNG, IL18RAP |
| cellular response to interleukin-2 | biological process | CDC5L |
| cellular response to interleukin-3 | biological process | GSK3B, CSF2RB, SH2B3, MT2A |
| cellular response to interleukin-4 | biological process | HSPA5, TCF7, RPL3, KEAP1, XBP1, MRC1, GATA3, RUFY4, SHPK, FASN, PML, ALAD, LEF1, IMPDH2, CORO1A, IL24, NFIL3, ADAMTS13, DCSTAMP, MCM2 |
| cellular response to interleukin-6 | biological process | TDGF1, PPARGC1A, FGG, SBNO2, FGF23, RELA, PTPRT, PID1, PTGIS, SELPLG, HAMP, FCAR, ST3GAL6 |
| cellular response to interleukin-7 | biological process | ATP5F1B, ATIC, P4HB, GIPC1, YBX1, HDGF, STIP1, BTK, CRKL |
| cellular response to interleukin-8 | biological process | EGR1 |
| cellular response to ionizing radiation | biological process | TP53, MGMT, ITGB1, CLOCK, MAPK14, INTS7, FBXO4, KDM4D, NAMPT, GADD45A, EEF1D, RAD9B, TANK, RAD9A, RAD1, GRB2, SWI5, ECT2, HUS1, IFI16, CDKN1A, BLM, RPL26, RAD51AP1, FIGNL1, INO80, NET1, RHNO1, SPIDR, TNKS1BP1 |
| cellular response to ionomycin | biological process | ZC3H12A, PPARGC1A, ZNF683, NFATC4 |
| cellular response to iron ion | biological process | TF, B2M, HFE, TFAP2A, ATP7A, BMP6, TFR2 |
| cellular response to iron ion starvation | biological process | HFE |
| cellular response to iron(II) ion | biological process | GSK3B |
| cellular response to iron(III) ion | biological process | CCNB1 |
| cellular response to jasmonic acid stimulus | biological process | AKR1C3, AKR1C2, AKR1C1, AKR1C4 |
| cellular response to L-arginine | biological process | CASTOR3 |
| cellular response to L-ascorbic acid | biological process | LEP |
| cellular response to L-glutamate | biological process | BCL11A, BAIAP2, OPA1, AMIGO1 |
| cellular response to L-glutamine | biological process | CYBB, CYBA |
| cellular response to laminar fluid shear stress | biological process | NFE2L2, KLF4, SREBF2, XBP1, ASS1, MAPK7, MAP2K5, KLF2 |
| cellular response to lead ion | biological process | DNMT1, ANXA5, ATP7A, ALAD, CLDN1 |
| cellular response to leptin stimulus | biological process | STAT3, LEP, CCNA2, FGF23, PID1, FGB, NR4A3, GCK |
| cellular response to leptomycin B | biological process | ID3 |
| cellular response to leucine | biological process | UBR2, SESN3, KLHL22, UBR1, LARS1, RRAGD, SESN2, RPTOR |
| cellular response to leucine starvation | biological process | SESN3, GCN1, RRAGB, LARS1, RRAGD, SESN2, IMPACT |
| cellular response to leukemia inhibitory factor | biological process | EED, HNRNPU, POLR1F, KDM5B, KLF4, GLDC, SHMT1, EFHC2, PDCD10, MYNN, BCLAF1, MPC1, PLA2G10, XRCC5, PIGA, EIF4A2, SYNGR1, SMARCA5, PFKP, TRIM25, ILDR1, NUP35, MRPL15, FZD4, NEFH, XBP1, SNX10, TFRC, MCF2, RNF138, WDR35, UBXN2A, ARID5B, SPOCK2, SBNO2, SLC25A5, CTBP2, BSPRY, RNMT, SRSF3, JARID2, PMM1, PADI2, DTX1, PARP16, CACYBP, NRP2, TLE4, EPS8, LAPTM5, SRSF7, PML, MAT2A, CTH, VEGFC, NFYB, HK2, KLF5, RIF1, ADAM23, MTF2, SPRY2, PTP4A3, NCL, GNPNAT1, PRDM5, PCOLCE2, BCAT2, SRM, ABCG4, RARG, PCOLCE, MRAS, KAT6B, SOCS3, INA, ABCD4 |
| cellular response to light stimulus | biological process | HIF1A, OPN5, RP1, GPR88, CRB1, TRPM1, RHO, OPN4, OPN3 |
| cellular response to lipid | biological process | IL1B, HIF1A, BAD, CCL5, ELK1, FIS1 |
| cellular response to lipid hydroperoxide | biological process | MGST1 |
| cellular response to lipopolysaccharide | biological process | TNF, IFNG, IL1B, IL6, ICAM1, CXCL8, TNFRSF1B, IL10, IL12A, HIF1A, CYP17A1, SERPINE1, AXL, TLR4, GSTP1, B2M, SRC, CCL5, NOS2, MAPK8, PLAU, FN1, CCR5, NR1H3, MAPK14, SELENOS, TNIP3, ZC3H12A, CHMP5, BCL10, TFPI, CAPN2, LY96, CXCL11, XBP1, STAR, IRAK1, PPARD, DAB2IP, MYD88, AKAP8, NUGGC, PAF1, STAP1, ASS1, BCR, IL1F10, PPARGC1A, CXCL6, HAVCR2, GHSR, UPF1, SBNO2, DEFA3, NOD2, CD274, MRC1, CD86, RELA, MEF2C, PDCD4, CTR9, PF4, CTSG, DEFA5, NLRP7, HMGB1, CEBPE, CDC73, PLSCR4, IL36RN, SHPK, EDNRB, PDE4B, NLRP3, NR1H4, CXCL2, PRPF8, CDK19, RIPK2, ABL1, ADAM9, NFKBIB, TICAM2, LITAF, TRAF6, CX3CR1, PDE4D, IRGM, CXCL1, ZFP36, CARD16, PDCD1LG2, NR1D1, TNFSF4, IL36G, CSF3, HAMP, IRF8, PLAA, DEFA4, BPI, FCAR, DEFA1, TNIP2, PYCARD, PPBP, CXCL3, IL24, TRIM41, PF4V1, IRF3, ADAMTS13, PABPN1, GFI1, SPON2, HDAC5, LBP, TBXA2R, CD40, CACTIN, ANKRD1, CXCL10, RARA, CCL2, CD36, CD80, CXCL5, TICAM1 |
| cellular response to lipoteichoic acid | biological process | TLR4, TLR2, RELA, TIRAP, RIPK2, TREM2, LBP, CD36 |
| cellular response to lithium ion | biological process | FAS, LIG4, GSK3B, CTNNB1, CDH1, SHH, CDKN1B, ADCY7, XRCC4, TPH2, NFATC4, ID2, MYOG, CALR |
| cellular response to low-density lipoprotein particle stimulus | biological process | ITGB1, CD9, SREBF2, SOCS5, CES1, CD81, SYK, LDLR, HMGCS1, NPC1, ITGB2, FCER1G, FGF21, CD36 |
| cellular response to luteinizing hormone stimulus | biological process | CCNA2, STAR |
| cellular response to macrophage colony-stimulating factor stimulus | biological process | PDE1B, FER, PDE2A, CSF1R, DCSTAMP |
| cellular response to magnesium ion | biological process | ANK3, SLC41A1, FBP1, SMPD3, KCNA1 |
| cellular response to magnetism | biological process | ESR2, ASCL1, MYOG |
| cellular response to manganese ion | biological process | HSPA5, PRKN, ATP13A2, TH, BACE1, LRRK2 |
| cellular response to mechanical stimulus | biological process | IL1B, TNFRSF1A, FAS, CASP1, PTGS2, SOX9, BAK1, HIF1A, IGF2, MAPK3, AKT1, GSK3B, CASP8, TLR4, ITGB1, EDNRA, CTNNB1, BAD, BMP4, MAPK8, MMP7, GJA1, KCNK4, HDAC4, BCL10, CNN2, MYD88, GCLC, BAG3, IL13, TNFRSF10B, SLC9A1, CYBA, FADD, MAP2K4, SLC38A2, ITGA2, GADD45A, CASP2, TNFRSF8, GOT1, ATP1A2, BNIP3, RAC1, PIEZO2, F11R, PTGER4, HABP4, MAP3K2, BMP6, WNT11, IRF1, AQP1, KCNJ2, MAP3K14, TNFSF14, TLR7, CASP8AP2, TNFRSF10A, ATP1A1, DAG1, TLR3, ENG, PDE2A, MAG, LTBR, TLR5, CD40, PIEZO1, AGT, CRADD, MAP3K1, ANKRD1, RIPOR2 |
| cellular response to menadione | biological process | NDOR1, DCPS |
| cellular response to mercury ion | biological process | IL4, FN1, AQP2, UBE2D3, AQP1 |
| cellular response to metal ion | biological process | HSD17B1, STAR, NQO1, FSTL3, SLC34A1 |
| cellular response to methotrexate | biological process | IL1B |
| cellular response to methyl methanesulfonate | biological process | TP53INP1 |
| cellular response to methylglyoxal | biological process | AKR1B1 |
| cellular response to mineralocorticoid stimulus | biological process | EDN1, GPER1 |
| cellular response to misfolded protein | biological process | UBE2W, DNAJB12, SDF2L1, STUB1, ATXN3, DNAJB14, DNAJC18, HDAC6 |
| cellular response to molecule of bacterial origin | biological process | FCGR2B, SIRT2, FZD5 |
| cellular response to molecule of fungal origin | biological process | CLEC7A, SYK, BTK |
| cellular response to monosodium glutamate | biological process | HPCA |
| cellular response to morphine | biological process | CCL5, AIF1, PPP1R9B, ADCY8 |
| cellular response to muramyl dipeptide | biological process | CHMP5, NOD2, PTPN22, RIPK2, ARHGEF2, TRIM41, NOD1 |
| cellular response to mycophenolic acid | biological process | PDGFB, EGR1 |
| cellular response to mycotoxin | biological process | CERS1 |
| cellular response to nerve growth factor stimulus | biological process | DNMT1, AKT1, E2F1, CIB1, APP, RAP1A, NTRK1, TAC1, ACAP2, ARPC3, RAPGEF2, RAB35, DYNC1LI2, KIF1B, NTRK2, RAPGEF1, KIDINS220, CBL, CALCA, ARF6, KAT2A, CRK, FOXO3, MICALL1, MAGI2, TRPV1, CDC5L |
| cellular response to nicotine | biological process | TNF, BAD, NTRK1, MSX1, RELA, TH |
| cellular response to nitric oxide | biological process | MTR, FOXO1, CCNA2, HNRNPD, AIFM1, GUCY1B1, CFLAR, MT3, AQP1, CRK, KCNC2, TRAF2, DPEP1 |
| cellular response to nitrite | biological process | HIF1A, PPARGC1A |
| cellular response to nitrogen starvation | biological process | MAP1LC3A, NPRL2, ATG5, BECN1, GABARAPL1, GABARAP, GABARAPL2, MAP1LC3B, MAP1LC3C |
| cellular response to nitrosative stress | biological process | ATM, ATG5, STOX1 |
| cellular response to norepinephrine stimulus | biological process | APP, APLP1 |
| cellular response to nutrient | biological process | HMOX1, LPL, XBP1, TNKS, CDKN2B, PDK2 |
| cellular response to nutrient levels | biological process | ICAM1, MTOR, ULK1, KCNB1, PRKAA2, UCN3, UCN2, TXN2, RPTOR, FAM107A |
| cellular response to oleic acid | biological process | CPS1, ASS1, DGAT2 |
| cellular response to organic cyclic compound | biological process | TGFB1, TNF, IL1B, CYP1A1, FAS, IL18, HIF1A, ESR2, CCNB1, MGMT, AKT1, STAT1, CASP3, CASP9, MDM2, CASP8, SRD5A1, STAT3, CCL5, RAP1A, CYP1B1, CCNA2, KLF4, PPP1R9B, BTRC, PTN, STAR, CCL3, HCFC1, SLC9A1, NOD2, CYBA, TIPARP, RAE1, HMGCS1, P2RY12, ITGA2, CDKN1B, KLF5, STING1, P2RX7, P2RY1, PAK3, PAK4, WNT10B, BMP2, SLC16A1, FOXF1, IGFBP5, KLF2, ALPL, GLI2, P2RY6, RAP1B, ANKRD1, LRRK2, SMAD5, CCL2 |
| cellular response to organic substance | biological process | IL1B, ICAM1, BCL2, CASP1, BAX, MAPK1, CASP3, MDM2, CD68, PLAU, IQGAP3, EGR1, TIMP3, PSAP, CCND1, CALB1, SYP, CYBA, CUX2, MAP2, LOX, SLC6A4, EGR2, POU3F2, TRIM71, CLEC3B, MCM7, TBX21, WNT10B, IL5RA, TREX1, CALR, SATB2 |
| cellular response to organonitrogen compound | biological process | APEX1, CAV3, NR1H4 |
| cellular response to osmotic stress | biological process | DDX3X, SERPINB6, PHLPP2, ZFAND1, LRRC28, LRRC8D, PKD2, LRRC8C, SLC2A4, LRRC8B, DYSF, RELB, PHLPP1 |
| cellular response to oxidative stress | biological process | SOD1, MGMT, NFE2L2, GPX1, PARP1, PARK7, BMP4, TXNDC8, HSPA1A, HSPA1B, G6PD, PRDX2, FOXO1, TXNDC2, ETV5, ATP2A2, SELENOS, KEAP1, RWDD1, DHRS2, TXNRD1, ZC3H12A, MSRA, TMEM161A, PRKRA, STAU1, CYBB, XBP1, SNCA, FANCD2, PRKD1, ADNP2, SETX, ZFAND1, HTRA2, PPARGC1A, PYCR2, ATP13A2, PRDX6, ENDOG, CYBA, NUDT2, VRK2, SIRT2, ERO1A, ATF4, GPX3, RAD52, NR4A2, PINK1, PRR5L, PYROXD1, NCF1, PRDX3, EIF2S1, ABL1, SLC25A24, CPEB2, PNPT1, GPX2, PRDX5, NME2, PRKAA2, FANCC, BRF2, MT3, PYCR1, VKORC1L1, ALDH3B1, NFE2L1, NCF4, SOD3, STX4, GPX7, SESN2, FOXO3, TREX1, LONP1, TXNRD2, MGAT3, LRRK2, PENK, AIF1, SRXN1 |
| cellular response to oxidised low-density lipoprotein particle stimulus | biological process | MYD88, SMPD3, ADTRP, MIA3, TLR6, CD36, TICAM1 |
| cellular response to oxygen levels | biological process | LPAR1, POU4F2, MYOD1 |
| cellular response to oxygen-glucose deprivation | biological process | TSC1, NAMPT, AIFM1, ATF4, AQP3, CBL, CACNB3 |
| cellular response to paclitaxel | biological process | WDR35 |
| cellular response to parathyroid hormone stimulus | biological process | ADAMTS1, HDAC4, FGF23, MEF2C, PHEX, WNT10B, SLC34A1 |
| cellular response to peptide | biological process | AKT1, AKR1B1, KLF4, PPP1R9B, KLF3, IRS2, SMPD3, KLF11, FIS1, KLF10, KLF5, KLF2, ANO1 |
| cellular response to peptide hormone stimulus | biological process | MDM2, CYP11A1, CYP11B1, SRC, CYP11B2, APEX1, RANGAP1, MAS1, MAX, XBP1, POR, MEN1, ZFP36L1, EDN1, CSK, MAP1B, CAV1, GPER1 |
| cellular response to peptidoglycan | biological process | NOD2, RELA, NLRP3, RIPK2, TREM2 |
| cellular response to pH | biological process | ASIC1, HVCN1, PKD2L1, GPLD1, GNA11, KCNK18, MCOLN1, GPR68 |
| cellular response to phenylalanine | biological process | FAS |
| cellular response to pheromone | biological process | GNG8 |
| cellular response to phorbol 13-acetate 12-myristate | biological process | SPHK2, MAP4K1, DEFB104A |
| cellular response to phosphate starvation | biological process | COMT, XPR1 |
| cellular response to platelet-derived growth factor stimulus | biological process | DNMT1, YES1, SRC, FN1, CCNA2, CORO1B, MTSS2, IQGAP1, MARS1, ERRFI1, PTN, PDGFD, HAS2, SYAP1, CBL, RDX, ATP7A, PDGFRB, HAS1 |
| cellular response to potassium ion | biological process | SOD1, CYP11B1, CYP11B2, SLC12A2, PPARGC1A, CRHBP, CARF, DLG4, CACNA1H, DLG2 |
| cellular response to potassium ion starvation | biological process | SLC38A3 |
| cellular response to progesterone stimulus | biological process | SRC |
| cellular response to prolactin | biological process | CDC5L |
| cellular response to prostaglandin D stimulus | biological process | AKR1C3, AKR1C2, PTGDR, TNC |
| cellular response to prostaglandin E stimulus | biological process | GNAS, AKT1, ADAMTS1, FN1, PPARG, P2RY4, AKAP8, GNB1, PTGER2, ADCY6, GNG2, PTGER4, PRKAA2, TNFSF4, PRKCE, ACACA, P2RY6 |
| cellular response to prostaglandin stimulus | biological process | APOB, AKR1C3, PPARG |
| cellular response to purine-containing compound | biological process | P2RY1, P2RY6, TRPM2 |
| cellular response to puromycin | biological process | XRN1 |
| cellular response to putrescine | biological process | HNRNPD |
| cellular response to pyrimidine ribonucleotide | biological process | P2RY6 |
| cellular response to radiation | biological process | ADIRF, NSMCE3 |
| cellular response to raffinose | biological process | ZFP36L1 |
| cellular response to rapamycin | biological process | GOLPH3, LARP1 |
| cellular response to reactive nitrogen species | biological process | MAP3K5, STAT6 |
| cellular response to reactive oxygen species | biological process | AKR1C3, PARK7, SRC, NME8, TPM1, PXN, RPS3, PKD2, UCP1, AGAP3, SMPD3, NCF1, PRDX3, MAPK9, FER, SLC8A1, PRDX5, FOS, CRYGD, BTK, PDGFRA, PPARGC1B, CAMKK2, TREX1, PDK2, MPV17 |
| cellular response to redox state | biological process | SMPD3, ARHGDIB, VASN |
| cellular response to resveratrol | biological process | PPARGC1A |
| cellular response to retinoic acid | biological process | SOX9, LEP, YES1, PPARG, STRA8, CYP26B1, ALDH1A2, KLF4, HOXA2, PTK7, HDAC2, FZD4, LTK, ADNP2, SETX, BRINP2, HTRA2, WNT7B, WNT9B, WNT3A, PHB2, GJB3, WNT8B, FZD7, SLC6A4, TEAD2, LYN, TNC, SNW1, ABL2, YAP1, TESC, WNT11, AQP1, RET, TWF2, WNT10B, MYOG, EPHA3, RARG, SERPINF1, BRINP1, PTK6, WNT9A, WNT3, WNT6, PTK2B, WNT5B |
| cellular response to salt stress | biological process | CAPN3, ZFP36L1, AQP1 |
| cellular response to selenite ion | biological process | EIF4A3 |
| cellular response to sodium arsenite | biological process | HNRNPA1, ZC3H12A, MAPK13 |
| cellular response to sorbitol | biological process | MAP2K4, MAP2K6, MAPK13 |
| cellular response to starvation | biological process | GAS6, ALB, SRD5A1, AKR1C3, BMPR2, FOXO1, GBA, HSPA8, PDK4, MAX, MAP1LC3A, MARS1, SREBF2, CTSV, RRAGA, EHMT2, WNT4, DNAJC15, WNT9B, RRAGB, PIK3C3, ZFYVE1, LAMP2, KRT20, WNT2B, ATG5, GLUL, GCGR, USP33, WDR45, ELAPOR1, RALB, GAS2L1, WIPI2, WDR45B, CADPS2, FBXO22, KLF10, MFSD2A, STK26, FNIP1, WIPI1, TNRC6A, FLCN, MAP1LC3B, RRAGD, PIK3C2B, SREBF1, CARTPT, DSC2, MYOD1, FADS1, TFEB, PPARA, CLEC16A, RPTOR, PCSK9, AMBRA1, MYH13, LRRK2, RIPOR1, CAV1, MAP1LC3C |
| cellular response to staurosporine | biological process | PLAU, CASP7, SLC34A1 |
| cellular response to steroid hormone stimulus | biological process | NR3C1, TFPI, NKX3-1, ATP1A3, ADTRP, URI1, ATP1A2, UBE2L3, NPC1, ATP1A1 |
| cellular response to sterol | biological process | RORA, INSIG1, RORC |
| cellular response to sterol depletion | biological process | NPC1L1 |
| cellular response to sucrose stimulus | biological process | CALCRL |
| cellular response to superoxide | biological process | GLRX2, ADPRS |
| cellular response to temperature stimulus | biological process | KCNK4, HTR1B, TRPM2, HTR2B, TRPV1 |
| cellular response to testosterone stimulus | biological process | SRD5A1, AACS, RWDD1, SPP1, ROCK2, ELK1, MSN |
| cellular response to tetrahydrofolate | biological process | SHMT1, SHMT2 |
| cellular response to thapsigargin | biological process | FIS1 |
| cellular response to Thyroglobulin triiodothyronine | biological process | NCOA2, NCOA1 |
| cellular response to thyroid hormone stimulus | biological process | KIT, BMP4, KLF9, CTSL, CTSB, PPARGC1A, GHSR, GAS2L1, RDX, CTSS, LMO2, CTSH, GATA1 |
| cellular response to thyrotropin-releasing hormone | biological process | TSHR |
| cellular response to thyroxine stimulus | biological process | GCLC |
| cellular response to topologically incorrect protein | biological process | HDAC6 |
| cellular response to toxic substance | biological process | HIF1A, PRKN, PINK1, FIS1, OPRD1, PPP1R9A, KCNC2, ABTB2 |
| cellular response to transforming growth factor beta stimulus | biological process | TGFB1, SOX9, DNMT1, YES1, SRC, CCL5, FN1, SOX5, OVOL2, HDAC2, PDCD5, FBN1, STAR, PTK2, PDGFD, WNT10A, PPARGC1A, WNT4, COL4A2, MEF2C, POSTN, EPB41L5, PDE3A, ZFP36L2, MAPK7, SOX6, TGFBR1, CX3CR1, PPM1A, ZFP36L1, CLEC3B, HYAL2, EDN1, CILP, CLDN1, ACVRL1, CRK, PDE2A, DLX1, WNT7A, SMAD3, WWOX, CRKL, ANKRD1, PENK, CAV1 |
| cellular response to triacyl bacterial lipopeptide | biological process | TLR2, TLR1 |
| cellular response to trichostatin A | biological process | MEF2C, ACTR2 |
| cellular response to triglyceride | biological process | GPLD1 |
| cellular response to tumor cell | biological process | TXNIP |
| cellular response to tumor necrosis factor | biological process | IL6, ICAM1, CXCL8, FAS, BRCA1, APOB, NFE2L2, CIB1, CCL5, GBA, CX3CL1, CCL16, HDAC4, CCL20, ERBIN, YBX3, AKAP12, CCL8, ZC3H12A, GSDME, TDGF1, CCL1, CCL14, DAB2IP, NKX3-1, CCL3, CD58, RPS3, BAG4, ASS1, CCL11, WDR35, PPARGC1A, CHI3L1, ZNF268, THBS1, CYBA, GATA3, RELA, HAS2, CCL22, CRHBP, RORA, POSTN, PID1, NFKBIA, GBP2, TANK, SMPD3, BIRC2, ZFAND6, HYAL3, GBP1, ZFP36L2, PRPF8, INPP5K, CCL26, ARHGEF2, MAP3K5, GBP3, ZFP36, CCL18, ZFP36L1, SLC2A4, NR1D1, CCL23, TCL1A, HYAL2, CCL19, IKBKB, CALCA, HAMP, TRADD, CCL3L1, FCAR, SMPD4, PYCARD, TNFRSF21, EDN1, MYOD1, MYOG, CCL7, KAT2A, CLDN1, ADAMTS13, ADAMTS7, KLF2, CD40, CACTIN, DCSTAMP, ADAMTS12, CCL17, CCL21, ANKRD1, CCL2, CCL15, TRPV1, GPER1 |
| cellular response to type I interferon | biological process | IFIT1, TREX1 |
| cellular response to unfolded protein | biological process | PACRG, HSPA8, OPTN, HSPA14, DERL1, DAB2IP, TMBIM6, PRKN, BAG3, ERN1, RHBDD1, HSPA13, PTPN1, TM7SF3, HSPB8, HSPA6, HSPA1A, HSPA1B |
| cellular response to UV | biological process | TP53, PTGS2, FMR1, BAX, BAK1, CDC25A, CASP9, ATR, PCNA, TP63, MYC, USP47, NPM1, DHX36, PIK3R1, FBXW7, TMEM161A, PTN, TP53INP1, USP28, RUVBL2, CREBBP, POLK, ATF4, NEDD4, COPS9, TRIAP1, TAF1, YY1, EP300, EIF2S1, RHBDD1, SDE2, NSMCE3, ERCC4, NFATC4, BMF, AQP1, RPL26, TREX1, INO80, NOC2L, MAPK13, POLD1, AURKB, RHNO1, N4BP1, ZBTB1 |
| cellular response to UV-A | biological process | PPID, MME, CERS1 |
| cellular response to UV-B | biological process | MFAP4, CRIP1, HYAL3, CDKN1A, HYAL2, MME |
| cellular response to UV-C | biological process | MDM2, POLH, C9orf116, CARD16, IMPACT, TP53 |
| cellular response to vascular endothelial growth factor stimulus | biological process | VEGFA, FLT1, AKT1, KDR, HSPB1, FN1, MAPK14, XBP1, DAB2IP, PRKD1, ANXA1, FLT4, RAMP2, GAS1, NOTCH1, RELA, MAP2K3, ITGB1BP1, ERN1, MT1G, EGR3, SEMA6A, SPRY2, PRKD2, NRP1, NR4A1 |
| cellular response to vasopressin | biological process | RANGAP1, CDC6, ADCY6 |
| cellular response to virus | biological process | IL12A, FMR1, MAPK14, LGALS8, DDX3X, ZC3H12A, LGALS9, GSDME, MAPK11, ADAR, IFI6, ARF1, IKBKE, RIOK3, POU2F2, IRGM, CCL19, RRP1B, GBF1, VWCE, GLI2, POU2AF1, TRIM6, PENK |
| cellular response to vitamin | biological process | BRIP1 |
| cellular response to vitamin B1 | biological process | MDM2 |
| cellular response to vitamin D | biological process | BGLAP, ITGB1, ADAMTS1, IL15, PTN, FGF23, PHEX, TNC, ATP2B1, FES, GDAP1, PENK |
| cellular response to vitamin E | biological process | PPARG |
| cellular response to vitamin K | biological process | GAS6, CCL5, POSTN |
| cellular response to water deprivation | biological process | AQP2, SIPA1 |
| cellular response to wortmannin | biological process | CDC5L |
| cellular response to X-ray | biological process | XRCC5, XRCC6, NIPBL, TP53BP1, HAMP, SFRP2 |
| cellular response to xenobiotic stimulus | biological process | E2F1, RB1, APOBEC3A, MCM7 |
| cellular response to zinc ion | biological process | MT1A, HVCN1, ATP13A2, MT1F, MT1HL1, MT1G, MT1M, MT1H, MT2A, MT1E, MT1X, GLRA1, MT3, KCNK3, MT1B, P2RX4, MTF1, GLRA2 |
| cellular response to zinc ion starvation | biological process | SLC39A5, SLC39A4 |
| cellular senescence | biological process | CDKN2A, H2AFX, PRMT6, NSMCE2, MAGEA2, SMC5, OPA1, CDKN2B, ULK3, PML, PRKCD, TBX3, CDKN1A, ID2, MAP2K1, SRF, HRAS, KAT6A, ECRG4, CALR, TBX2 |
| cellular sodium ion homeostasis | biological process | SLC12A2, SLC9A1, ATP1A4, ATP1A3, ATP1A2, NEDD4L, SLC8A1, TMPRSS3, ATP1B1, ATP1A1, ATP1B2, ATP4A, ATP1B3, AGT, C7, ATP4B |
| cellular sphingolipid homeostasis | biological process | ORMDL3, RTN4, ORMDL2, ABCA2 |
| cellular stress response to acid chemical | biological process | KLF2 |
| cellular stress response to acidic pH | biological process | NOX1 |
| cellular triglyceride homeostasis | biological process | XBP1, DGAT2, C1QTNF3, NR1H4 |
| cellular water homeostasis | biological process | AQP5, AQP7, ANXA7, AQP11, CLN3, AQP1, SCT, SCTR |
| cellular zinc ion homeostasis | biological process | SLC30A9, SLC30A5, MT1A, SLC39A12, ATP13A2, MT1F, ATP7B, SLC30A10, SLC39A10, SLC39A5, SLC30A8, SLC39A8, SLC30A1, MT1HL1, MT1G, SLC39A6, MT1M, SLC39A13, MT1H, MT2A, MT1E, MT1X, MT3, LCK, MT1B, SLC39A4, SLC39A14, SLC39A7 |
| cementum mineralization | biological process | HACD1, ALPL |
| CENP-A containing nucleosome assembly | biological process | HIST1H4A, NASP, NPM1, RBBP7, SMARCA5, CENPN, RSF1, OIP5, CENPI, CENPT, ITGB3BP, MIS18A, HJURP, RBBP4, CENPU, RUVBL1, CENPX, CENPW, CENPC, CENPM, CENPA, CENPS, CENPP, CENPQ, CENPK, CENPO, CENPH, H4-16 |
| central nervous system development | biological process | SOX9, LIG4, ZEB2, SOX3, ARNT2, GSTP1, PTEN, SRC, PROP1, SHH, CHD7, DSCAML1, NPAS2, TIMP2, GLI3, PAM, PTS, STK3, NDN, ZIC2, NHLH1, ASIC2, NCKAP1, SCIN, ACVR1B, STK4, ADGRA2, SPINK5, SH3GL2, COX7B, AHI1, PRKN, ALDH3A2, SH3GL3, SNTG2, BCAN, COL2A1, DRP2, ROBO2, ID3, PAX8, MOG, JARID2, ACAN, BTD, PDX1, HAPLN4, NRCAM, ARSB, EMX2, SMO, CELSR1, DCX, GABRA4, NHLH2, HAPLN1, NPTX1, ANKLE2, RNF103, TPP1, MBP, SPINK6, POU3F3, ZEB1, B3GNT5, WWP1, GBA2, ADAM22, SOX6, SZT2, DCLK1, TRIO, EIF2B2, DHX30, FAIM2, TBX3, ADAM23, S100B, CAPG, HAPLN3, NMUR2, ALDH5A1, DMBX1, SERPINI1, HAPLN2, CHRD, VAX2, MAL, MNX1, TIMP4, ELP3, PSPN, PDGFC, ZIC3, NGFR, PTPRZ1, ZBTB16, LMX1A, ZIC5, NPAS1, ECRG4, MTF1, CYP26C1, THOC6, GSX1, ADORA2A, DNER, KLK6, SH3GL1, GLIS2, NCAN, GRIK1, GRHL3, SHC3, CHST8, CNTN6, NES, RELN, JRKL, TP53, TBX2, UGT8, NHEJ1 |
| central nervous system interneuron axonogenesis | biological process | TCTN1 |
| central nervous system maturation | biological process | CX3CR1 |
| central nervous system myelin formation | biological process | ERCC2, TENM4, ABCA2 |
| central nervous system myelin maintenance | biological process | CLU, PTEN, FA2H, MYRF |
| central nervous system myelination | biological process | KCNJ10, ASPA, CNTN2, ID4, B4GALT6, B4GALT5, MAG, CNTNAP1, MYRF |
| central nervous system neuron axonogenesis | biological process | PTEN, PTK2, ARHGAP35, B4GALT6, B4GALT5, CHRNB2 |
| central nervous system neuron development | biological process | FGFR1, LEP, FGF8, GABRB1, AGBL4, NPY, NTRK2, ASCL1, BTG2, MAP2, FOXG1, GBA2, HPRT1, ATP7A, GATA2, CDK5 |
| central nervous system neuron differentiation | biological process | TULP3, BCL11B, NR4A2, SMO, SPOCK1, POU4F1, LMX1A |
| central nervous system projection neuron axonogenesis | biological process | EPHB2, EPHB1, NR4A2, MYCBP2, DCLK1, CHRNB2, EPHB3, SPTBN4 |
| central nervous system vasculogenesis | biological process | CTNNB1, RTN4, WNT7B, ENG, WNT7A |
| central tolerance induction | biological process | FOXJ1 |
| central tolerance induction to self antigen | biological process | AIRE |
| centriole assembly | biological process | E2F4, NUP62, RBM14 |
| centriole elongation | biological process | C2CD3 |
| centriole-centriole cohesion | biological process | NIN, SGO1, RTTN, CEP68, CEP250, CROCC |
| centromere complex assembly | biological process | CENPI, CENPO, CENPV |
| centrosome cycle | biological process | BRCA1, CDK1, XRCC2, PCM1, HAUS2, NPM1, PPP1R12A, HAUS4, ARL2, NUP62, CDK5RAP2, HAUS5, CEP120, BBS4, TUBE1, SDCCAG8, GADD45A, PLK1, CETN3, HAUS6, SSX2IP, PARD6A, UVRAG, CKAP5, PARD6B, CEP68, SLC16A1, CHD3, FES, GOLGA2, CROCC, KIAA1614, PARD6G |
| centrosome duplication | biological process | BRCA2, CHORDC1, ARHGEF10, CCP110, NDC80, ROCK2, PKD2, USP33, CKAP5, SASS6, STIL, NDE1, BRSK1, CEP192 |
| centrosome localization | biological process | KIF5B, NUBP1, NIN, DYNC1LI2, BICD2, RANBP2, SYNE2, NDE1, SUN2, PLXNA2, TMEM201 |
| centrosome organization | biological process | KIAA0101 |
| centrosome separation | biological process | CNTROB, NEK2 |
| centrosome-templated microtubule nucleation | biological process | NIN, CEP192 |
| ceramide 1-phosphate transport | biological process | PLEKHA3, CERT1, CPTP, GLTP, PLEKHA8, MTTP |
| ceramide biosynthetic process | biological process | GBA, SGMS2, TLCD3B, CERS5, SMPD1, CLN8, DEGS2, CYP4F22, DEGS1, SPTLC3, FA2H, SPTLC1, SPTSSA, SAMD8, P2RX7, ALOXE3, CERS4, SMPD2, SPTLC2, SMPD4, CERS1, CERS6, CERS3, ELOVL1, ALOX12B, AGK, ASAH2 |
| ceramide catabolic process | biological process | ACER3, ACER1, ACER2, ASAH2 |
| ceramide metabolic process | biological process | ASAH1, PPP2CA, ORMDL3, PLPP2, FUT6, HTRA2, PLPP1, SMPD1, PSAP, FUT5, CLN8, NSMAF, SMPD3, ACER3, CERT1, CERK, ORMDL2, PLA2G15, FUT7, PLPP3, FUT3, ACER1, PPP2R1A, ACER2, ASAH2 |
| ceramide phosphoethanolamine biosynthetic process | biological process | SGMS2, SAMD8 |
| ceramide transport | biological process | ABCA12, PLEKHA3, CERT1, CPTP, GLTP, PLEKHA8 |
| cerebellar cortex development | biological process | EZH2, KIF14, CDK5, CLP1 |
| cerebellar cortex formation | biological process | PTPN11, MAP2K1, CDK5 |
| cerebellar cortex morphogenesis | biological process | SMO, GLI1, GLI2 |
| cerebellar granular layer development | biological process | MDK, TTBK2, FAIM2 |
| cerebellar granular layer structural organization | biological process | KIF14 |
| cerebellar granule cell differentiation | biological process | NRXN1, OPHN1, KNDC1, GRID2, PROX1, WNT7A |
| cerebellar granule cell precursor proliferation | biological process | SHH, PSMG1, RERE, RORA, GBX2 |
| cerebellar granule cell precursor tangential migration | biological process | TTBK2, PLXNA2 |
| cerebellar molecular layer formation | biological process | DLL1 |
| cerebellar molecular layer morphogenesis | biological process | ZNF365 |
| cerebellar neuron development | biological process | CRK, CRKL |
| cerebellar Purkinje cell differentiation | biological process | SLC25A46, TTLL1, PSAP, RORA, LHX1, TTC21B, ATP7A, FAIM2, LHX5, HERC1 |
| cerebellar Purkinje cell layer development | biological process | HSPA5, B4GALT2, MYH10, AARS1, KLHL1, UQCRQ, FAIM2, SEZ6L, NAGLU, SEZ6 |
| cerebellar Purkinje cell layer formation | biological process | WHRN |
| cerebellar Purkinje cell layer maturation | biological process | ARCN1, RERE |
| cerebellar Purkinje cell layer morphogenesis | biological process | COQ8B, SPTBN2 |
| cerebellar Purkinje cell layer structural organization | biological process | KIF14, DLL1 |
| cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation | biological process | LHX1, LHX5 |
| cerebellum development | biological process | ESR2, NCOA2, MT-CO1, MT-ND4, GART, ATIC, HNRNPD, NLGN4X, RERE, PTN, CPLANE1, SEMA4C, PPARGC1A, FCGR2B, CNTN1, LHX1, PSEN1, TTBK2, TTC21B, CD3E, NEUROD1, MECP2, CDK5R1, NCOA1, FOXP2, GBX1, ABAT, FAIM2, CDK5R2, LPAR1, CKB, EN1, LHX5, MYO16, SSTR3, GBX2, CDK5, PTPRS, KCNC1, FOXC1, LMX1A, SCN5A, HAP1, RPGRIP1L, TP53, AIF1, PTF1A |
| cerebellum morphogenesis | biological process | GNPAT, LRP6, ABL1 |
| cerebellum structural organization | biological process | HSPA5 |
| cerebellum vasculature development | biological process | IMMP2L |
| cerebellum vasculature morphogenesis | biological process | FZD4 |
| cerebral cortex cell migration | biological process | EGFR, EFHC1, PEX13, PSEN1, HTR6, DIXDC1, NKX2-1 |
| cerebral cortex development | biological process | BAX, HIF1A, SRD5A1, BAD, XAB2, H2AFX, EMX1, BTBD3, BBS2, GART, ATIC, GRIN1, PPP1R9B, TMEM14B, TACC1, NOTCH2NLC, KIF14, NOTCH2NLA, COL3A1, ASPM, TSC1, MKKS, TACC2, NPY, CEP120, MCPH1, NSUN5, WDR47, MDK, NTRK2, TBR1, BBS4, SLC38A2, PHACTR1, LRP6, PSEN1, ASCL1, EMX2, CDON, SMO, CNTNAP2, TACC3, WDR62, YWHAE, PAX5, BNIP3, NCOA1, FOXG1, FOXP2, LRP1, GNG12, TH, CDK5, PTPRS, CRK, NDE1, CCDC85C, BCL2A1, NF1, TRAPPC9, CRKL, LHX2, RELN, NEFL |
| cerebral cortex GABAergic interneuron development | biological process | RAC3 |
| cerebral cortex GABAergic interneuron differentiation | biological process | ASCL1, DLX1, DLX2, NKX2-1 |
| cerebral cortex GABAergic interneuron fate commitment | biological process | DLX1, DLX2 |
| cerebral cortex GABAergic interneuron migration | biological process | CNTN2, DRD1, ARX, DRD2 |
| cerebral cortex neuron differentiation | biological process | EMX1, EOMES, ZNF335, CHD5, GDPD5, ID4, HPRT1, OPHN1, EURL, NKX2-1 |
| cerebral cortex radial glia guided migration | biological process | GLI3, RTN4 |
| cerebral cortex radially oriented cell migration | biological process | DISC1, CDK5R1, POU3F3, POU3F2, DIXDC1, FBXO45 |
| cerebral cortex regionalization | biological process | EMX1, EOMES, TRA2B, EMX2 |
| cerebral cortex tangential migration | biological process | ARX, RELN, FBXO45 |
| cerebrospinal fluid circulation | biological process | LRRC6, SLC9A3R1, KIAA0556 |
| cerebrospinal fluid secretion | biological process | JHY, CELSR2, AQP1 |
| cervix development | biological process | LHX1 |
| cGMP biosynthetic process | biological process | GUCY2F, GUCY1B1, GUCY1A2, GUCY1A1, NPR1, GUCY2D, NPPC, NPR2 |
| cGMP catabolic process | biological process | PDE1A, PDE9A, PDE5A, PDE10A, PDE2A |
| cGMP metabolic process | biological process | PDE9A, RORA, PDE5A |
| cGMP transport | biological process | SLC22A7 |
| cGMP-mediated signaling | biological process | APOE, ADNP, IRAG1, PDE9A, GUCY2F, GUCY1B1, EDNRB, PDE3A, PRKG1, NPR1, HTR2C, AQP1, GUCA2B, NPPC, PDE2A, NPR2, CD36, HTR2B |
| chaperone cofactor-dependent protein refolding | biological process | HSPA8, HSPH1, PTGES3, CD74, HSPA14, ST13, DNAJB12, DNAJB4, DNAJC7, TOR2A, ERO1A, DNAJB14, HSPA13, DNAJB1, DNAJC18, GAK, TOR1B, BAG1, HSPA6, HSPE1, HSPA1A, HSPA1B |
| chaperone mediated protein folding independent of cofactor | biological process | CCT2 |
| chaperone-mediated autophagy | biological process | HSP90AA1, HSPA8, BAG3, STUB1, LAMP2, SYNPO2 |
| chaperone-mediated autophagy translocation complex disassembly | biological process | HSPA8 |
| chaperone-mediated protein complex assembly | biological process | HSP90AA1, HSPA4, CLU, HSPD1, PTGES3, PSMG1, NDUFAF1, CCT2, BBS12, MKKS, HOPX, PSMG3, THEG, PFDN6, APCS, LONP1, PSMG2, HSPA1A |
| chaperone-mediated protein folding | biological process | FKBP4, FKBPL, CLU, FKBP6, HSPA8, PEX19, FKBP5, CHORDC1, PPIB, SGTA, ST13, DNAJB8, PDIA4, PPID, DNAJC24, CSNK2A1, FKBP1B, DNAJC5, TRAP1, P3H1, DFFA, DNAJB2, UNC45B, UNC45A, HSPB1 |
| chaperone-mediated protein transport | biological process | PEX19, TIMM9, BAG3, TIMM8A, TIMM13, TIMM8B, TIMM10, CLIP3 |
| chaperone-mediated protein transport involved in chaperone-mediated autophagy | biological process | HSPA8 |
| chemical homeostasis | biological process | UMOD, POU3F3 |
| chemical homeostasis within a tissue | biological process | HOMER2, HOMER1 |
| chemical synaptic transmission | biological process | MAPK1, CTNNB1, TAC1, VDAC1, GABRB1, FGF12, PCDHB9, CHRNA5, GRM3, GRM4, SLC6A2, USP14, RAPSN, ASIC2, KCNMB1, SYPL1, GJD2, UTS2, GABRA2, CHRNE, GRIN1, NLGN4X, HTR3B, HTR3A, PMP22, CACNA1E, GIPC1, SNAPIN, MPZ, HRH1, TPGS1, KCNN1, DLGAP1, CPLX1, SLC1A2, MYCBPAP, NLGN2, PDE7B, KCND2, SLC12A6, PCDHB4, HCRTR1, NPY, SYT1, HTR7, CHRNA2, SLC18A3, MYO5A, DTNA, SYT5, CRH, GABRG2, GABRB3, SLC1A3, UNC119, SPG11, RIT2, NRXN2, PCDHB3, CORT, KCNQ3, GLRA3, SLITRK5, CHRNB1, SYN1, PMCH, GABRA5, GAD1, SLC12A4, CACNA1A, KCNQ2, LRP6, CHRM3, CHRNA7, AMPH, ATXN3, CHRND, DOC2A, CHRFAM7A, CEP89, CHRNA10, BSN, GABRB2, GABRA4, SNAP25, KCNC4, KIF5A, GABRG1, NLGN4Y, CNP, CHRNA3, GRIA2, MECP2, DLG1, NPTX1, SV2C, UNC13C, AKAP9, SDCBP, MBP, UNC13B, GRIK5, CACNA1G, GABARAP, HTR1E, SLC1A6, EXOC4, PTCHD1, APBA2, HRH4, PCDHB14, GABRP, NPFF, NPTX2, NPBWR1, GRIN2B, HOMER1, PCDHB16, PCDHB5, GABRD, PDYN, DLG4, APBA1, GRM2, GPR176, SYN2, HTR3E, CACNB4, GLRA1, HTR2C, CHRNA6, CARTPT, PCDHB10, OR10H1, SLC12A7, GRM6, CPNE6, HTR1B, CDH8, SLC12A5, LPAR3, HR |
| chemical synaptic transmission, postsynaptic | biological process | AKT1, GSK3B |
| chemoattraction of axon | biological process | LRP1, ROBO3 |
| chemokine (C-C motif) ligand 11 production | biological process | TNFSF4, CXCR3 |
| chemokine (C-C motif) ligand 19 signaling pathway | biological process | CCR7 |
| chemokine (C-C motif) ligand 21 signaling pathway | biological process | WNK1, OXSR1, CCR7, CCL21 |
| chemokine (C-C motif) ligand 5 production | biological process | TUSC2 |
| chemokine (C-X-C motif) ligand 12 signaling pathway | biological process | OXSR1, CXCL12 |
| chemokine biosynthetic process | biological process | IL18 |
| chemokine production | biological process | S100A9, AIRE, S100A8 |
| chemokine-mediated signaling pathway | biological process | CXCL8, CCL5, CCR5, CX3CL1, CCL16, CCL20, ACKR4, CCR1, CCL8, CXCL11, CCL1, CCL14, CCL3, XCR1, CCL11, CXCL6, CXCR5, CCL22, PF4, ACKR3, CXCR2, CCR6, TFF2, CXCL2, CCL26, CX3CR1, CXCL1, CCL18, CCRL2, CXCR3, CCL23, CCL19, CCL3L1, CXCR1, CCR7, CXCR6, PPBP, CXCL3, CCL7, ACKR1, GPR75, CCR10, FOXC1, PF4V1, CMKLR1, GPR17, GPR35, CXCL12, CCR3, PTK2B, CCL17, CCL21, ACKR2, CXCL10, CCL2, CXCL5, CCR4, CCL15 |
| chemorepulsion involved in interneuron migration from the subpallium to the cortex | biological process | NRG1, NRG3 |
| chemorepulsion involved in postnatal olfactory bulb interneuron migration | biological process | SLIT2, ROBO1 |
| chemorepulsion of axon | biological process | NTN1, UNC5C, SEMA3B |
| chemorepulsion of branchiomotor axon | biological process | PLXNA4 |
| chemorepulsion of dopaminergic neuron axon | biological process | RYK |
| chemosensory behavior | biological process | PRKCG, OBP2B, TRPV1 |
| chemotaxis | biological process | IL4, CXCL8, ANOS1, CMTM2, FLT1, MAPK1, PLAUR, CCL5, FPR1, PLAU, CCR5, PROK2, PLA2G6, S100A9, CX3CL1, MAPK14, CCN1, CCL16, CCL20, ACKR4, LECT2, CXCR4, NUP85, CCR1, CCL8, LGALS9, ENPP2, CMTM7, CYSLTR1, CXCL11, RALA, CCL1, PLP2, PLD1, RALBP1, CCL3, XCR1, CMTM3, CXCL16, CREB3, CCL11, DEFB103A, C5, CXCL6, RNASE2, S1PR1, AMOT, MACO1, ROBO2, CXCR5, PLGRKT, CKLF, CCL22, DEFB4A, PF4, ACKR3, DEFB1, HMGB1, CXCR2, FPR3, CCR6, CXCL2, RAC1, CCL26, RAC2, FER, CX3CR1, S100A8, CXCL1, CCL18, CMTM1, PARVA, CCRL2, PIK3CG, CXCR3, CCL23, IL16, C3AR1, CCL19, PTGDR2, MAP2K1, C5AR2, PDGFRB, CCL3L1, TYMP, CXCR1, FPR2, CCR7, NCKAP1L, DEFA1, PIK3CD, CXCR6, HRAS, PPBP, SPN, CXCL3, AZU1, CCL7, CCL28, CXCL14, HRG, FGF2, PDGFRA, PTAFR, CCR10, RARRES2, PF4V1, MOSPD2, CMKLR1, LTB4R2, PIP5K1C, FES, L1CAM, CXCL12, SLIT2, CCR3, CMTM8, CCL17, DOCK2, CCL21, RIPOR2, CCL27, ROBO1, ACKR2, FGF10, CXCL10, CCL2, C5AR1, CXCL5, CCR4, CCL15, ROBO3 |
| chiasma assembly | biological process | UBE2B, MSH5, TEX11, SYCP1, CCNB1IP1, BRIP1 |
| chitin catabolic process | biological process | CHI3L1, CTBS, CHI3L2, OVGP1 |
| chloride ion homeostasis | biological process | ATP6V1B1, SLC12A2, SLC12A6, SLC12A4, CA12, SLC12A9, SLC12A7, SLC12A5, SLC12A3, SLC12A8 |
| chloride transmembrane transport | biological process | CFTR, CLCA4, CLCN2, SLC26A8, SLC26A4, GABRB1, SLC26A3, SLC12A2, PCYOX1, GABRA2, CLCN1, CLCNKA, ANO6, FXYD1, CLCN7, TTYH2, SLC1A4, SLC12A6, CLIC4, SLC26A9, GABRG2, GABRB3, SLC1A3, BEST3, GLRA3, GABRA5, SLC26A5, ANO7, SLC26A7, CLCC1, SLC12A4, CLIC3, FXYD3, PACC1, GABRB2, GABRA4, CLCNKB, GABRG1, ANO9, SLC26A2, CLCN3, CLDN17, CLIC5, GABRP, CLIC1, GABRD, NMUR2, GLRA1, SLC12A9, SLC12A7, SLC5A1, CLIC6, SLC12A5, GABRR2, CLCN4, CLCN6, SLC4A8, TTYH1, GABRA1, GABRA3, SLC26A1, GABRQ, CLDN4, ANO1, ANO2, ANO10, SLC4A1, SLC12A3, SLC26A10, SLC26A6, TTYH3, ANO8, GABRR3, ANO4, GABRG3, SLC12A8, GLRA2, CLCN5, SLC17A7, APOL1 |
| chloride transport | biological process | CFTR, CLCA4, CLCN2, SLC26A8, GABRB1, SLC26A3, CLNS1A, SLC12A2, PCYOX1, GABRA2, WNK4, CLCN1, CLCNKA, ANO6, FXYD1, CLCN7, TTYH2, CLIC4, SLC26A9, GABRG2, GABRB3, BEST3, GLRA3, GABRA5, ANO7, SLC26A7, CLCC1, CLIC3, FXYD3, PACC1, GABRB2, GABRA4, CLCNKB, GABRG1, ANO9, CLCN3, CLDN17, CLIC5, GABRP, CLIC1, GABRD, NMUR1, GLRA1, CLIC6, SLC12A5, GABRR2, CLCN4, CLCN6, TTYH1, GABRA1, GABRA3, SLC26A1, GABRQ, CLDN4, ANO1, ANO2, ANO10, SLC4A1, SLC26A6, TTYH3, ANO8, GABRR3, ANO4, GABRG3, GLRA2, CLCN5, SLC4A10 |
| cholecystokinin signaling pathway | biological process | CCKAR |
| cholesterol biosynthetic process | biological process | CFTR, G6PD, IDI1, LBR, ARV1, ACLY, FDFT1, CES1, LSS, HSD17B7, PMVK, NSDHL, DHCR24, ACAA2, HMGCR, EBP, MSMO1, HMGCS2, HMGCS1, SQLE, APOA1, NPC1L1, INSIG1, CYB5R3, PRKAA2, APOA5, CYP51A1, TM7SF2, DHCR7, MVD, MVK, PLPP6, INSIG2 |
| cholesterol biosynthetic process via 24,25-dihydrolanosterol | biological process | CYP51A1 |
| cholesterol biosynthetic process via desmosterol | biological process | SC5D, DHCR24, EBP, DHCR7 |
| cholesterol biosynthetic process via lathosterol | biological process | SC5D, DHCR24, EBP, DHCR7 |
| cholesterol catabolic process | biological process | APOE, SCARB1, TRERF1, MT3, CYP46A1, SCARF1, SNX17, AKR1D1 |
| cholesterol efflux | biological process | APOE, APOB, NPC2, STX12, SCARB1, ABCG1, ABCA5, APOA1, SOAT1, APOC1, NPC1, APOA5, ABCG4, ABCA7, APOC3, APOM |
| cholesterol ester hydrolysis involved in cholesterol transport | biological process | CES1 |
| cholesterol esterification | biological process | SOAT1, LCAT |
| cholesterol homeostasis | biological process | NR5A2, APOE, APOB, EPHX2, NPC2, NR1H3, PLA2G10, LPL, SREBF2, XBP1, CES1, HDAC9, LIPG, DGAT2, LDLR, SCARB1, FABP3, ABCG1, MALL, GPIHBP1, NUS1, LIPC, RORA, CAV3, LIMA1, MED13, ANGPTL3, APOA1, SOAT1, TTC39B, MYLIP, NR1H4, TMEM97, NPC1, INSIG1, NR1D1, ACSM3, LAMTOR1, APOA5, LRP5, HNF4A, NFE2L1, CETP, FGFR4, GRAMD1B, PCSK9, ABCA2, DISP3, RALY, LRP5L, ABCB11, APOC3, ACSM1, SEC24A, ACOX1, APOM, LCAT, MTTP, AKR1C1, PLA2G12B, NR1H2, CAV1 |
| cholesterol import | biological process | LDLR, SCARB1, APOA1, STARD4, STARD5, CD36 |
| cholesterol metabolic process | biological process | APOE, IL4, APOB, PON1, APP, CYP11A1, CYP11B1, LEP, LEPR, CAT, CYP11B2, LIPE, NPC2, IDI1, LBR, ARV1, ERLIN1, SCAP, OSBPL1A, FDFT1, SREBF2, CES1, STAR, PPARD, SULT2B1, HDLBP, PMVK, NSDHL, MBTPS1, DHCR24, LDLR, SMPD1, OSBPL5, HMGCR, ABCG1, VLDLR, EBP, FDX1, APOF, MSMO1, CLN8, CH25H, LIPC, HMGCS2, HMGCS1, LIMA1, ANGPTL3, SQLE, APOL2, APOA1, SOAT1, NPC1L1, MBTPS2, GBA2, APOC1, NPC1, INSIG1, CYB5R3, PRKAA2, ERLIN2, LRP5, SREBF1, CYP51A1, TM7SF2, NFE2L1, STARD3, DHCR7, MVD, PIP4P1, CETP, CYP46A1, CYP2D6, MVK, PCSK9, DISP3, CUBN, LCAT, CLN6, APOL1, CYP2C9, APOBR, INSIG2 |
| cholesterol storage | biological process | SOAT1 |
| cholesterol transport | biological process | APOB, CFTR, NPC2, ARV1, VPS4B, LDLR, SCARB1, OSBPL5, ABCG1, OSBPL2, LIPC, ABCA5, APOA1, NPC1L1, NPC1, STARD3, CETP, LCAT, CD36, CAV1 |
| cholesterol transport involved in cholesterol storage | biological process | STARD4 |
| choline catabolic process | biological process | SLC44A1, SARDH, DMGDH |
| choline metabolic process | biological process | CHKA, BCHE, DMGDH, ENPP6 |
| choline transport | biological process | SLC22A2, SLC44A4, SLC44A1, SEC14L1, PSEN1, SLC5A7, SLC44A2 |
| chondroblast differentiation | biological process | CCN1, FGF2, RARA, GDF5 |
| chondrocyte development | biological process | SOX9, BMPR2, COL11A1, CHSY1, BPNT2, ACAN, SMPD3, FGF18, RUNX2, SFRP2, MSX2, SULF1, RARG, COMP, SULF2, CHST11, EIF2AK3 |
| chondrocyte development involved in endochondral bone morphogenesis | biological process | SMPD3, SERPINH1 |
| chondrocyte differentiation | biological process | TGFB1, SOX9, FGFR3, FGFR1, BMP4, FGF9, MAPK14, SNX19, PTH1R, BMPR1A, NFIB, COL2A1, RUNX1, CYTL1, MEF2C, CREB3L2, HMGA2, WNT2B, GPLD1, IFT80, MEF2D, SOX6, TGFBI, SIX2, CCN3, RUNX2, WNT10B, BMP2, GLI2, WNT7A, SLC39A14, WNT5B, OSR2 |
| chondrocyte differentiation involved in endochondral bone morphogenesis | biological process | SOX9, TRIP11, AXIN2, IHH |
| chondrocyte hypertrophy | biological process | SOX9, MEX3C |
| chondrocyte proliferation | biological process | FGFR3, CCN2, HMGA2, MMP16, MMP14, COMP, IHH, Grn |
| chondroitin sulfate biosynthetic process | biological process | DCN, DSE, CSGALNACT1, CHST12, SLC35D1, CHSY1, UGDH, CSPG4, BCAN, B3GALT6, CHST15, XYLT2, XYLT1, CHSY3, BGN, CHST9, CHST13, CHPF, CSPG5, NCAN, CHST3, CHST11, CSGALNACT2, CHST7 |
| chondroitin sulfate catabolic process | biological process | DCN, HEXA, HEXB, IDS, CSPG4, BCAN, ARSB, BGN, IDUA, CSPG5, NCAN |
| chondroitin sulfate metabolic process | biological process | DSE, CSGALNACT1, BPNT2, DSEL, CHST11 |
| chondroitin sulfate proteoglycan biosynthetic process | biological process | PXYLP1, B3GAT1, CSGALNACT1, XYLT2, CYTL1, XYLT1, B3GAT2, B3GAT3, CSGALNACT2 |
| chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | biological process | CSGALNACT1, CSGALNACT2 |
| chordate embryonic development | biological process | FAS, BRCA1, BRCA2, FGFR1, CENPU, TRIP6 |
| chorio-allantoic fusion | biological process | CCN1, WNT7B, BMP5, ZFP36L1, LEF1 |
| chorion development | biological process | PAXIP1 |
| chorionic trophoblast cell differentiation | biological process | MAP3K4, E2F7, E2F8, FZD5, HTRA1 |
| chromatin assembly | biological process | TP53, M1AP, RBBP4, CHAF1A, NOC2L |
| chromatin assembly or disassembly | biological process | MTA2, SMARCA5, BAZ1B, HDAC8, SUV39H2, CHD3, HIRIP3, ASF1B |
| chromatin maintenance | biological process | SUPV3L1 |
| chromatin organization | biological process | EZH2, SOX2, LRWD1, EED, HMGN1, RBL1, HDAC4, SUPT4H1, HNRNPU, RBL2, IKZF1, CBX2, RNF20, ARID2, ATAD2, H2AZ2, WAC, DPY30, KDM5B, JAK2, MORF4L2, HMGN3, EPC2, SRCAP, UIMC1, ENY2, ASH2L, MORF4L1, PADI1, OGT, PHF1, ACTL6A, MBTD1, CBX3, RBBP7, CARM1, RNF168, GATAD1, HDAC11, NSD1, NSD3, USP16, USP3, SMARCA5, SMARCA4, BCORL1, ASXL1, DTX3L, HDAC2, RSF1, SETDB2, BRD9, TCF7L1, COPRS, MRGBP, KDM6B, ZMPSTE24, DEK, ATRX, RBBP5, BCOR, TLK2, H2AC12, TSPYL2, TDRD3, SUDS3, MACROH2A2, KDM4A, YEATS4, SUZ12, KMT5B, SMARCE1, DMAP1, HDAC9, RUVBL2, LOXL2, PHF2, H2AZ1, HCFC1, FOXA1, WDR5, ARID1B, EHMT2, RIOX1, HIRA, HLTF, SMARCD3, EMSY, MSL3, L3MBTL4, H2AJ, ING2, KDM4C, BABAM1, L3MBTL1, DCAF1, TDG, KDM4D, H2AC6, HDAC8, KANSL2, CBX8, BABAM2, USP22, KMT2D, RELA, ABRAXAS1, JARID2, HMG20B, PADI2, H2AC7, HMGA2, SFMBT1, MEN1, CBX6, SMARCB1, H2AC20, H2AC21, SMARCC2, CHD5, EHMT1, UTP3, ING3, TLK1, TAF6L, UTY, PRKCB, SATB1, CHD9, DOT1L, H2AP, NSD2, BMI1, KMT2A, RBBP4, H2AC18, KDM3B, KMT2C, KAT5, DNAJC2, SETD5, BAZ2A, PHF8, SETD1B, TET3, SMARCA |
| chromatin remodeling | biological process | ESR1, SOX9, BRDT, TNP1, RB1, BRD4, TP63, MYC, TOP1, HDAC4, KDM5B, NPM1, PAX7, SMARCA2, SRCAP, BAZ2B, ACTL6A, CBX3, GATAD1, NUDT5, HCFC2, SMARCA5, SMARCA4, DR1, HDAC2, RSF1, RERE, KDM6B, ATRX, BAZ1B, HMGB3, KDM4A, CHD1L, SMARCE1, DMAP1, BAZ1A, RUVBL2, HCFC1, FOXA1, ARID1B, INO80C, SMARCD3, KDM4C, KDM4D, GATA3, JARID2, INO80B, HMGB1, SMARCB1, SMARCC2, TAF6L, SATB1, RBBP4, BAZ2A, SMARCA1, BPTF, MYSM1, PBRM1, RUVBL1, ZNHIT1, TADA2A, ARID1A, KDM4B, SMARCC1, ACTR6, SUV39H2, CHRAC1, NPM3, SMARCAD1, VPS72, INO80E, KAT2A, KDM5A, SCMH1, SMARCD1, PADI4, ACTL6B, ZBTB7A, KAT2B, INO80, HDAC5, SMYD1, MORC2, SATB2, ZBTB1 |
| chromatin silencing | biological process | UBR2, TNP1, H2AFX, EED, H2AZ2, MORF4L2, MORF4L1, H2AC12, MACROH2A2, PCGF2, PCGF1, H2AZ1, MSL3, H2AJ, H2AC6, KMT2D, SIRT2, H2AC7, HMGB1, H2AC20, H2AC21, DOT1L, H2AP, BMI1, MECP2, H2AC18, MACROH2A1, CTBP1, H1-0, H2AB1, H2AC11, H2AC1, HDAC5, H2AC4, H2AB2 |
| chromatin silencing at rDNA | biological process | MBD2, HIST1H4A, SMARCA5, SIRT2, BAZ2A, H3C1, H3-3A, H4-16, H3C13 |
| chromatin silencing at telomere | biological process | SIRT2, DOT1L, RIF1, HAT1 |
| chromatin-mediated maintenance of transcription | biological process | CTNNB1, ZMIZ1, ARID1B, CDCA4, PADI2, ELOF1, SERTAD2, ARID1A, SMARCD1, SERTAD1, ZMIZ2, KMT2B |
| chromosome breakage | biological process | BRCA1, BRCA2, RFWD3, HMGA2 |
| chromosome condensation | biological process | PRM1, PRM2, CDK1, H1FNT, TOP2A, H1-4, NCAPD3, NCAPH2, NCAPH, NCAPG, AIFM1, H1-2, HMGA2, H1-8, BANF2, SMC4, H1-0, H1-5, H1-1, H1-3, NCAPD2, NCAPG2, SMC2 |
| chromosome localization to nuclear envelope involved in homologous chromosome segregation | biological process | KASH5 |
| chromosome organization | biological process | LIG4, BRCA2, ERCC1, MYC, SFPQ, ZMPSTE24, SMC3, CENPT, NCAPH2, PELO, PTTG2, DCLRE1C, ITPA, GEM, ZNF830, MRE11, YY1, SMCHD1, SMC1A, SMC4, CENPW, RAD51D, RLF, CDCA8, SMC2, RAD54L, TP53 |
| chromosome organization involved in meiotic cell cycle | biological process | DMC1, ATRX, CCNE1, MEIOC, RAD50, CCNE2 |
| chromosome passenger complex localization to kinetochore | biological process | RCC2 |
| chromosome passenger complex localization to spindle midzone | biological process | KLHL21 |
| chromosome segregation | biological process | DDX3Y, BRCA1, BIRC5, ERCC2, NR3C1, REC8, TOP2A, TOP1, STAG3, CENPE, ABRAXAS2, DDX3X, NEK8, NUP37, MIS12, ARL8B, BUB3, NUP43, DSN1, CIAO2A, BEX4, NDC80, CIAO1, ESPL1, CDCA2, CENPN, SETDB2, CIAO2B, TLK2, OIP5, BUB1, RPS3, CENPT, CDK5RAP2, ZNF207, CEP85, NEK11, SRPK1, MIS18A, SLC25A5, UBE2I, SGO1, HJURP, CENPF, SEH1L, TLK1, USP44, BANF2, MAU2, RAD21, STAG2, STAG1, NTMT1, RIOK3, TTK, NUMA1, SKA2, ARL8A, NSL1, UVRAG, KNSTRN, SGO2, CENPW, USP9X, RCC1, CENPC, PMF1, MMS19, SKA1, TOP3B, NDE1, RGS14, SPC25, NEK6, PPP2R1A, NAA60, INCENP, NEK2, NUF2, CENPH |
| chromosome separation | biological process | RECQL5, NCAPD3, TTK, SMARCAD1, NCAPD2 |
| chronic inflammatory response | biological process | CCL5, GJA1, CAMP, CCL11, THBS1, PTGES, S100A8, VNN1 |
| chronic inflammatory response to antigenic stimulus | biological process | TNF, IL1B, AHCY |
| chronological cell aging | biological process | SERPINE1, ENG |
| chylomicron assembly | biological process | P4HB, APOA1, PLAGL2, LPCAT3, APOC3, MTTP |
| chylomicron remnant clearance | biological process | APOE, LDLR, LIPC, APOC1, APOC3, LMF1 |
| chylomicron remodeling | biological process | LPL, GPIHBP1, APOA1, APOC3 |
| ciliary basal body organization | biological process | JHY, FOXJ1, CCP110, RTTN, CROCC |
| ciliary basal body-plasma membrane docking | biological process | OFD1, PCM1, CEP57, HAUS2, CETN2, RAB11A, CEP70, CCP110, NEDD1, TCTN2, RAB3IP, TCTN1, KIF24, TCTN3, CEP41, HAUS4, CSNK1E, DYNC1I2, AHI1, CDK5RAP2, B9D1, DCTN3, HAUS5, CEP131, CEP43, CSNK1D, SDCCAG8, TTBK2, CEP89, TUBB, PLK1, SCLT1, YWHAE, TUBB4B, C2CD3, CEP162, CEP97, AKAP9, CEP164, TUBG1, ALMS1, CEP63, TMEM67, HAUS6, DCTN2, CNTRL, CEP290, ACTR1A, CKAP5, TUBB4A, MAPRE1, YWHAG, CEP250, SFI1, PCNT, PRKAR2B, NDE1, PPP2R1A, NINL, CLASP1, FBF1, MARK4, IQCB1, CEP192, B9D2, CEP72, CC2D2A, SSNA1, NEK2, RPGRIP1L, CEP83 |
| ciliary body morphogenesis | biological process | TSKU, JAG1, FOXE3 |
| ciliary neurotrophic factor-mediated signaling pathway | biological process | IL6R, IL6ST, CNTFR, LIFR, CNTF |
| ciliary receptor clustering involved in smoothened signaling pathway | biological process | WDR19, IFT122, SSNA1 |
| ciliary transition zone assembly | biological process | DZIP1L |
| cilium assembly | biological process | 39326, DYNC2H1, TEKT3, KIF3A, DYNLL1, PTPDC1, OFD1, RO60, IFT88, SEPTIN2, PCM1, CDKN3, CFAP70, DZIP1, DNAAF1, WDR19, TXNDC15, CEP20, CCDC113, ATP6V1D, NME5, ACTR3, E2F4, CCDC65, CEP70, FOXJ1, IFT74, CEP19, BBS2, FHDC1, STK36, TMEM17, TRAF3IP1, TCTN2, CFAP53, NEK1, RAB3IP, IFT52, TTC26, RFX3, RAB1A, TCTN1, KIF24, TCTN3, BBS5, CEP41, DYNC2LI1, RPGR, UBXN10, CPLANE1, ATXN10, SNX10, CFAP298, OCRL, FNBP1L, AHI1, CPLANE2, PTPN23, INTU, B9D1, MKKS, WDR35, ARL3, BBS9, IQUB, RAB8B, WDR90, RSPH9, DISC1, CEP131, CCDC66, ABLIM1, NOTCH1, TTC8, ARL6, PLA2G3, SNAP29, PIBF1, BBS4, DCDC2, ARL13B, EHD4, IFT46, FAM92A, TTBK2, DZIP1L, CEP89, CELSR2, RAB23, ONECUT2, TMEM107, SCLT1, DNAI2, RSPH6A, C2CD3, CEP162, MACIR, CEP164, CDC14B, IFT43, TBC1D32, KIAA0586, IFT80, FAM161A, TMEM67, TTC39C, WDR60, HYLS1, CEP126, SSX2IP, BBIP1, CFAP221, POC1B, CLUAP1, WDR34, CEP290, ACTR2, KIF27, PARVA, CFAP410, ATP6V0D1, NPHP3, SEPTIN11, HDAC6, CILK1, GALNT11, CEP250, IFT122, EHD2, PCNT, CFAP20, AVIL, WWTR1, EHD3, ONECUT1, PKHD1, RAB8A, ARMC9, NU |
| cilium movement | biological process | CCDC103, DNAH1, DNAH5, DNAH11, DNAI1, CFAP70, ARMC4, CFAP91, LRRC6, TTC29, DNAAF1, DNAH17, ZBBX, CFAP53, RSPH9, CCDC63, DNAAF4, HYDIN, DNAH3, CELSR2, ZMYND10, CFAP61, DNAI2, RSPH6A, WDR78, CFAP206, CCDC114, CFAP221, CFAP73, CFAP100, CCDC40, DNAAF5 |
| cilium movement involved in cell motility | biological process | SPAG16, DNAH1, WDR63, RSPH9, RSPH6A, CFAP46, GAS8 |
| cilium or flagellum-dependent cell motility | biological process | DNAH1 |
| cilium organization | biological process | DZIP1, TTC29, MNS1, KIFAP3, SLC9A3R1, PKD2, RTTN, CFAP126, CFAP61, ROPN1B, FAM161A, CFAP410, CATIP, MARK4, TTC17 |
| cilium-dependent cell motility | biological process | EFHC1, DNAH2, DNAH17, CCDC65, RFX3, DNAH3, DNAH8, DNAAF2, DRC1 |
| circadian behavior | biological process | TP53, NR1D2, USP2, SIX3, GPR157, GPR176, BTBD9 |
| circadian regulation of gene expression | biological process | AHR, NRIP1, HNF1B, NCOA2, CLOCK, CREM, NPAS2, TOP1, PER3, HNRNPU, OGT, PER1, GFPT1, HUWE1, HDAC2, LGR4, MAGED1, CSNK1E, RBM4B, EGR1, PPARGC1A, BHLHE40, PPP1CB, NAMPT, ID3, ZFHX3, PER2, ATF4, RORA, CSNK1D, USP2, KMT2A, ID4, KDM2A, MYCBP2, PML, CRY1, CAVIN3, HDAC3, NR1D1, RAI1, DRD3, ID2, CARTPT, ARNTL, NGFR, KDM5A, KDM8, RELB, MYBBP1A, DRD2, PPARA, CRY2, RORC, MC3R, BHLHE41 |
| circadian regulation of translation | biological process | PER1, HNRNPD, PER2, RBM4 |
| circadian rhythm | biological process | FAS, NRIP1, SERPINE1, GSK3B, LEP, NOS2, NCOA2, PROKR2, PROK2, CLOCK, NTRK1, CREM, NPAS2, TOP1, PROK1, PER3, TYMS, DYRK1A, KLF9, PER1, HNRNPR, HEBP1, LGR4, STAR, CPT1A, SETX, RBM4B, ASS1, F7, PPARGC1A, ADIPOQ, BHLHE40, DDC, HTR7, NAMPT, MTNR1A, ID3, NONO, NTRK2, TIMELESS, HS3ST2, PER2, ATF4, RORA, DBP, TPH1, EP300, SLC6A4, ID4, EGR3, KLF10, NDUFA9, CRY1, TPH2, HDAC3, NCOR1, NR1D1, SREBF1, ID2, ARNTL, IMPDH2, THRAP3, NGFR, JUND, NFIL3, PROX1, CLDN4, AANAT, CRY2, RORC, RPE65, TP53, BHLHE41 |
| circadian sleep/wake cycle | biological process | AHCY, TH |
| circadian sleep/wake cycle, non-REM sleep | biological process | BTBD9 |
| circadian sleep/wake cycle, REM sleep | biological process | SRD5A1, STAR |
| circadian temperature homeostasis | biological process | EGR1, NR1D1, TNFRSF11A |
| circulatory system development | biological process | HEY2, HEY1 |
| cis assembly of pre-catalytic spliceosome | biological process | DDX23, SNRNP200 |
| citrate metabolic process | biological process | ACLY, IREB2, ACO2, CS, ACO1 |
| citrate transport | biological process | SLC13A3, SLC13A1, SLC13A5, SFXN5 |
| citrulline biosynthetic process | biological process | CPS1, ALDH18A1, CAD |
| citrulline metabolic process | biological process | DDAH1, ASS1, DDAH2 |
| clathrin coat assembly | biological process | PIK3C2A, AP2S1, FCHO1, EPS15, PICALM, SNAP91, CLINT1, CLTA, AP2B1, FCHO2, NSG2, CLTC, CLTB, CALY, NSG1, HIP1R, SGIP1 |
| clathrin coat disassembly | biological process | HSPA8, GAK, DNAJC6 |
| clathrin-coated pit assembly | biological process | PICALM, GAK |
| clathrin-dependent endocytosis | biological process | CANX, AP2S1, INPP5F, FCHO1, FCHSD2, FNBP1L, AP2A2, PICALM, SNAP91, AP2M1, GPR107, SLC9B2, CLTA, AP2B1, FCHO2, CLTC, GAK, DNAJC6, CLTB, DLL1, PIP5K1C, AP2A1, SGIP1 |
| clathrin-dependent endocytosis of virus by host cell | biological process | env, SIGLEC1 |
| clathrin-dependent extracellular exosome endocytosis | biological process | ITGA4 |
| clathrin-dependent synaptic vesicle endocytosis | biological process | ITSN2, ITSN1 |
| clearance of foreign intracellular DNA | biological process | APOBEC3A |
| cleavage furrow formation | biological process | SNX33, SNX9, SPIRE1, SNX18, SPIRE2, AURKB |
| cleavage furrow ingression | biological process | ALKBH4 |
| cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | NOL9 |
| cleavage involved in rRNA processing | biological process | NHP2, NOB1 |
| cloaca development | biological process | AHI1 |
| cloacal septation | biological process | BMP4, TP63, WNT11 |
| closure of optic fissure | biological process | SOX11, PHACTR4 |
| club cell differentiation | biological process | NFIB, RBPJ, NKX2-1 |
| clustering of voltage-gated potassium channels | biological process | CNTN2, CNTNAP2, KCNIP2 |
| clustering of voltage-gated sodium channels | biological process | GLDN, NRCAM, SCLT1, NFASC, AGRN, SPTBN4, MYOC |
| CMP phosphorylation | biological process | AK9 |
| CMP-N-acetylneuraminate biosynthetic process | biological process | NANS |
| CMP-N-acetylneuraminate transmembrane transport | biological process | SLC35A1 |
| co-translational protein modification | biological process | STT3B, STT3A, PDF |
| coagulation | biological process | SEMG1, SEMG2 |
| cobalamin metabolic process | biological process | MTR, MTRR, ABCC1, CD320, MMADHC, MMAB, TCN1, AMN, PRSS3, TCN2, MMACHC, CUBN, CBLIF, MMAA, CTRB1, ABCD4 |
| cobalamin transport | biological process | ABCC1, CD320, TCN1, AMN, TCN2, CUBN, CBLIF |
| cobalt ion transport | biological process | SLC30A5, MMGT1, TCN1, SLC39A8, TCN2, CBLIF |
| cocaine metabolic process | biological process | BCHE |
| cochlea development | biological process | CCNA2, KCNK2, HES1, DCHS1, NEUROG1, PSAP, OPA1, CALB1, GATA3, GABRB3, GABRA5, SLC26A5, GABRB2, SLITRK6, VANGL2, TIFAB, GATA2, EPHA4, HEY2, KCNK3, SOBP, MCM2, PVALB, RPGRIP1L |
| cochlea morphogenesis | biological process | SOX9, PTK7, DVL1, FZD2, FRZB, NEUROG1, MYO3B, HPN, VANGL2, DVL2, ZEB1, TIFAB, SIX1, POU3F4, MYO3A, EYA1, CTHRC1, GLI2, GRHL3 |
| cochlear nucleus development | biological process | BCL2, SCRIB, SEC24B |
| coenzyme A biosynthetic process | biological process | PANK2, PPCDC, ACOT7, PPCS, COASY, PANK4, DCAKD, PANK1 |
| coenzyme A metabolic process | biological process | ACLY, HMGCR, MCCC2 |
| coenzyme A transmembrane transport | biological process | SLC25A17, SLC25A42 |
| coenzyme biosynthetic process | biological process | PANK2 |
| cognition | biological process | LHCGR, GNAS, HLA-DRA, CHD7, GTF2A1L, GPR155, CTNS, CBR3, C12orf57, SLC1A4, RP9, NSUN5, DGCR2, CHRNA7, TMPRSS11E, CUX2, CHL1, NIPBL, SETD5, MAGT1, LINS1, CYFIP1, MFSD2A, PTCHD1, METTL23, ST3GAL4, TH, HRH3, LCE1D, CHRM1, CHRNB2, CHRNA4, INS, FAM107A, STRA6, SLC8A2, DOP1B, SOBP, NF1, GRM5, MGAT3, TNF, C5AR1 |
| cohesin loading | biological process | MAU2, NIPBL |
| cold acclimation | biological process | SAXO1, APPL2 |
| collagen biosynthetic process | biological process | P3H3, TRAM2, COL5A1, P3H4, ADAMTS3, SERPINH1 |
| collagen catabolic process | biological process | MMP2, MMP9, CTSD, MMP12, MMP7, MRC2, CTSK, CTSL, CTSB, MMP15, MMP28, MMP23B, MMP16, PEPD, MMP14, PHYKPL, MMP20, ADAMTS2, MMP25, CTSS, MMP13, MMP21, ADAMTS14, MMP10, MMP19, COL15A1, FURIN, PRTN3, MMP11, COL19A1, TMPRSS6, MMP17, COL13A1, KLK6, ADAMTS3, MMP8 |
| collagen fibril organization | biological process | CYP1B1, ANXA2, COL11A1, COL5A2, TNXB, COL12A1, LOXL2, COL3A1, COL11A2, VIPAS39, COL2A1, SERPINF2, ACAN, P4HA1, COL1A2, LOX, TGFB2, FOXC2, TGFBR1, ATP7A, ADAMTS2, ADAMTS14, SFRP2, PLOD3, COL5A1, LOXL3, COL5A3, PXDN, FOXC1, MMP11, COMP, P3H4, ADAMTS3, NF1, SERPINH1, DPT, GREM1 |
| collagen metabolic process | biological process | HIF1A, P3H3, TNXB, TNS2, VPS33B, VIPAS39, SMPD3, COL1A2, P2RX7, PLOD3, P3H1 |
| collagen-activated signaling pathway | biological process | ITGA2, UBASH3B, OSCAR, ITGA11 |
| collagen-activated tyrosine kinase receptor signaling pathway | biological process | DDR1, COL4A1, SYK, COL4A2, COL4A6, COL4A3, UBASH3B, COL4A4 |
| collateral sprouting | biological process | BDNF, ZEB2, NIN, DVL1, EFNA5, ABL1, HDAC6 |
| collateral sprouting in absence of injury | biological process | APP, COBL |
| collecting duct development | biological process | WNT9B, NOTCH1 |
| colon epithelial cell migration | biological process | ARSB |
| columnar/cuboidal epithelial cell development | biological process | ROS1 |
| comma-shaped body morphogenesis | biological process | HES1, LHX1 |
| commissural neuron axon guidance | biological process | VEGFA, RYK, EPHB2, NFIB, FZD3, SMO, DAG1, NRP1, PTCH1, ROBO3 |
| commissural neuron differentiation in spinal cord | biological process | DRAXIN |
| commitment of neuronal cell to specific neuron type in forebrain | biological process | TBR1, BCL11B, ASCL1, GATA2, SATB2 |
| common bile duct development | biological process | HES1 |
| common myeloid progenitor cell proliferation | biological process | GSTP1, ITPKB, FBXO4, CEACAM1, NR4A3 |
| common-partner SMAD protein phosphorylation | biological process | TGFB1, BMP4, SPTBN1, PML, SMAD2, TGFBR2 |
| compartment pattern specification | biological process | NOTCH1, DLL1, LFNG, DLL3 |
| complement activation | biological process | C3, CLU, C1QB, CFD, CFHR1, C6, C5, CFH, C1S, COLEC11, FCN3, CFB, C1QC, MASP1, CFP, FCN1, RGCC, C1R, C1QA, MASP2, C2, MBL2, C8G, C7 |
| complement activation, alternative pathway | biological process | C3, CFD, C5, CFH, CFB, CFP, VSIG4, C8G, C7, CFHR5 |
| complement activation, classical pathway | biological process | C3, CLU, CD46, C1QBP, C1QB, CD55, C6, C4BPB, C5, C1S, SUSD4, C1QC, IGLL5, CR2, IGLL1, C1R, APCS, C1QA, SERPING1, MASP2, C2, MBL2, CFI, C8G, C7, C1RL |
| complement activation, lectin pathway | biological process | KRT1, COLEC11, FCN3, MASP1, FCN1, MASP2, MBL2, VWA1 |
| complement component C5a signaling pathway | biological process | C5AR2, C5AR1 |
| complement receptor mediated signaling pathway | biological process | FPR3, GPLD1, CR2, C3AR1, C5AR2, FPR2, CMKLR1, C5AR1 |
| complement-dependent cytotoxicity | biological process | RAB27A |
| complement-mediated synapse pruning | biological process | ITGAM, TREM2, C1QA |
| condensed mesenchymal cell proliferation | biological process | DCHS1, SIX2 |
| conditioned place preference | biological process | OPRL1 |
| conditioned taste aversion | biological process | GRIN1, TBR1, FOS, DRD1, CHRNB2 |
| connective tissue development | biological process | CCN2, FOXA1, LOX, SLC39A13 |
| connective tissue growth factor biosynthetic process | biological process | IL4 |
| connective tissue replacement involved in inflammatory response wound healing | biological process | TGFB1, HIF1A, IL1A, F2R |
| constitutive secretory pathway | biological process | TMEM167B, TRAPPC11, RAB11B, TMEM167A |
| contact inhibition | biological process | PTPRJ, SMO, YAP1 |
| contractile actin filament bundle assembly | biological process | SRF |
| convergent extension | biological process | PTK7, LRP6 |
| convergent extension involved in axis elongation | biological process | VANGL2, WNT11, SFRP2 |
| convergent extension involved in gastrulation | biological process | MKKS, NPHP3 |
| convergent extension involved in neural plate elongation | biological process | DVL1, VANGL2, DVL2 |
| convergent extension involved in organogenesis | biological process | DVL1, FRZB, VANGL2, DVL2 |
| conversion of ds siRNA to ss siRNA | biological process | DICER1 |
| conversion of ds siRNA to ss siRNA involved in RNA interference | biological process | DICER1 |
| conversion of methionyl-tRNA to N-formyl-methionyl-tRNA | biological process | MTFMT |
| COP9 signalosome assembly | biological process | COPS8, TESPA1, WNT3A, COPS7B, COPS7A |
| COPI coating of Golgi vesicle | biological process | TMED2, ARFGAP3, TMED10, TMED9, GBF1, ARFGAP2 |
| COPI-coated vesicle budding | biological process | TMED10 |
| COPII vesicle coating | biological process | SERPINA1, F5, USO1, AREG, SEC22B, SEC31A, RAB1A, SEC16A, TGFA, NSF, SEC24C, SEC13, STX5, SCFD1, PPP6C, TRAPPC3, CTSC, MCFD2, CNIH1, CD59, LMAN1, COL7A1, KLHL12, CNIH3, TFG, TBC1D20, GORASP1, SAR1B, CSNK1D, TMED2, PPP6R3, PDCD6, TRAPPC5, ANKRD28, BET1, SEC24B, TRAPPC10, SEC23A, KLHL21, GOSR2, SEC24D, TMED10, TRAPPC2L, TRAPPC2, F8, NAPA, TRAPPC4, CTSZ, TRAPPC1, CNIH2, PREB, GRIA1, GOLGA2, PEF1, RAB1B, SEC24A, TRAPPC9, TRAPPC6B, SEC16B, FOLR1 |
| COPII-coated vesicle budding | biological process | SEC23B, SEC31A, VAPB, SEC13, VAPA, SEC23A, SEC31B |
| COPII-coated vesicle cargo loading | biological process | SEC23B, SAR1A, SEC31A, RAB1A, SEC24C, SEC13, TBC1D20, SEC24B, SEC23A, SEC24D, MIA3, SEC31B, SEC24A |
| copper ion export | biological process | ATP7B, ATOX1, ATP7A |
| copper ion homeostasis | biological process | CUTC, XIAP, COMMD1, SCO2 |
| copper ion import | biological process | STEAP4, ATP7B, STEAP2, ATP7A, SLC31A1, STEAP3 |
| copper ion import across plasma membrane | biological process | SLC31A1 |
| copper ion transmembrane transport | biological process | SLC31A2, SLC31A1 |
| copper ion transport | biological process | FKBP4, COX17, CUTC, MMGT1, SLC31A2, SCO1, ATP7B, ATOX1, HEPH, ATP7A, SLC31A1, HEPHL1, SCO2 |
| copulation | biological process | PI3, ABAT |
| cornea development in camera-type eye | biological process | WNT9B, WNT2B, SOX11, WNT9A, WNT6, KERA, FOXE3 |
| corneocyte development | biological process | PSAP |
| cornification | biological process | CYP26B1, KRT38, KRT75, KRT24, SPINK5, KRT73, TMEM79, KRT23, KRT84, KRT6B, TGM1, SPRR1A, TGM5, KRT6A, CAPNS1, KRT18, CELA2A, KRT20, KRT71, SPRR3, PKP4, FLG, KRT32, DSP, PCSK6, DSG1, SPINK6, CSTA, KRT19, KAZN, PPL, PI3, SPRR1B, SPRR2B, KRT6C, KRT17, PERP, KLK13, CAPN1, KRT81, DSC3, PKP2, DSG2, EVPL, KRT83, DSC2, KLK5, KRT86, KRT8, IVL, JUP, KRT85, KRT82, SPRR2D, DSG3, KRT9, CERS3, KRT78, FURIN, KRT15, KRT74, PKP3, KRT14, KRT7, KRT13, KRT2, KRT72, KRT80, KRT77, KLK12, DSG4, ST14, LCE3D |
| cornified envelope assembly | biological process | PSAP, STX4, DMKN, UGCG |
| coronary artery morphogenesis | biological process | VEGFA, ARID2, NOTCH1, LRP2, SEC24B, TGFBR1, NRP1, HAND2 |
| coronary sinus valve morphogenesis | biological process | NOTCH1 |
| coronary vasculature development | biological process | DYNC2H1, MYH10, LTBP1, PTK7, CPLANE1, TAB1, DCTN5, PRDM1, MEGF8, SMAD6, NDST1, LRP2, AP2B1, SUFU, MMP21, ZBTB14, APLNR, VEGFB, ADAMTS6, GPC3, PRICKLE1, PLXND1, SNX17 |
| coronary vasculature morphogenesis | biological process | SGCD, HEY2 |
| coronary vein morphogenesis | biological process | VEGFA, NOTCH1 |
| corpus callosum development | biological process | RYK, RTN4R, CORO1C, EPHB2, NSUN5, WDR89, LPAR1, CDK5, PTPRS, RTN4RL2, EPHB3, HERC1, RTN4RL1, RPGRIP1L |
| corpus callosum morphogenesis | biological process | ZEB2, NIN, C12orf57, SZT2, TSKU |
| cortical actin cytoskeleton organization | biological process | TNF, EPB41L1, NCKAP1, CIT, EPB41L3, ROCK2, PLEK, ROCK1, LLGL1, RHOQ, DLG1, FMNL2, CAVIN3, IKBKB, ARF6, LLGL2, EHD2, NCKAP1L, AKAP11, CDK5, FHOD3, TLN1, FHOD1, CALR, EPB41, FMNL1, EPB41L2, FMNL3 |
| cortical cytoskeleton organization | biological process | RHOU, WDR1, EPB41L3, RHOG, ANLN, RHOQ, RHOBTB3, RAC1, RAC2, RAC3, RTKN, RHOJ, RHOV |
| cortical microtubule organization | biological process | EZR, DLG1 |
| corticospinal neuron axon guidance | biological process | SCN1B |
| corticospinal neuron axon guidance through spinal cord | biological process | SLIT2 |
| corticospinal tract morphogenesis | biological process | ZEB2, NIN, EPHA4, CDH11, FBXO45 |
| corticosterone secretion | biological process | SELENOM |
| corticotropin hormone secreting cell differentiation | biological process | FGF8, BMP2 |
| corticotropin secretion | biological process | CRHR1 |
| cortisol biosynthetic process | biological process | CYP11B1, CYP11B2, CACNA1H |
| cortisol metabolic process | biological process | CYP11A1 |
| cortisol secretion | biological process | GHRL |
| cotranslational protein targeting to membrane | biological process | TRAM1, ARL6IP1, SRP19, SSR2, SEC62, SRPRA, SRP14, SSR1, SEC61A1 |
| coumarin catabolic process | biological process | CYP2A6 |
| coumarin metabolic process | biological process | CYP1A1, UGT1A8, CYP2A7, CYP2A6, CYP2D6, UGT1A7 |
| covalent chromatin modification | biological process | SETD5 |
| cranial ganglion development | biological process | CTNNB1 |
| cranial nerve development | biological process | CHD7, SLC1A3, EPHB1, ERBB3 |
| cranial nerve morphogenesis | biological process | PLXNA4 |
| cranial skeletal system development | biological process | CEP55, TGFB2, RIC1, FOXE1, SH3PXD2B, CRKL |
| cranial suture morphogenesis | biological process | BMP4, TWIST1, INSIG1, MSX2, INSIG2 |
| craniofacial suture morphogenesis | biological process | FOXN3, NEUROG1, MEGF8, RAB23, MMP16, MMP14, TIFAB, FREM1 |
| CRD-mediated mRNA stabilization | biological process | HNRNPU, SYNCRIP, YBX1, IGF2BP1 |
| creatine biosynthetic process | biological process | GAMT, GATM |
| creatine metabolic process | biological process | CKM, SLC6A8, GAMT, CKMT2, GATM, CKB |
| creatine transmembrane transport | biological process | SLC6A8 |
| creatine transport | biological process | SLC6A8, SLC16A12 |
| creatinine metabolic process | biological process | MME |
| cristae formation | biological process | ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, DMAC2L, ATP5MC3, ATP5PF, ATP5F1E, ATP5PD, OMA1, DNAJC11, SAMM50, ATP5MC1, ATP5F1D, ATP5MC2, CHCHD6, APOO, IMMT, ATP5MG, ATP5MF, ATP5ME, AFG3L2, MICOS13, CHCHD3, LETM1 |
| cross-receptor inhibition within G protein-coupled receptor heterodimer | biological process | RAMP3, CALCR |
| CTP biosynthetic process | biological process | NME8, NME7, NME5, NME9, CTPS1, NME6, NME2, NME3, NME1, NME4, CTPS2 |
| CTP salvage | biological process | UCK1, UCKL1, UCK2 |
| CUT catabolic process | biological process | EXOSC10, EXOSC3, DIS3, EXOSC2 |
| cuticle development | biological process | TMEM79, DUOX2, DUOX1 |
| CXCL12-activated CXCR4 signaling pathway | biological process | CXCR4 |
| cyanate catabolic process | biological process | TST, MPST |
| cyclic nucleotide biosynthetic process | biological process | ADCY2, ADCY10, GUCY2F, GUCY1B1, GUCY1A2, GUCY1A1, ADCY6, ADCY8, ADCY7, ADCY9, NPR1, GUCY2D, ADCY4, ADCY5, NPR2 |
| cyclic nucleotide catabolic process | biological process | CNP |
| cyclic purine nucleotide metabolic process | biological process | AMPD2 |
| cyclic-nucleotide-mediated signaling | biological process | NUDT4 |
| cyclooxygenase pathway | biological process | PTGS1, PTGS2, AKR1C3, PTGDS, PTGES3, PTGES2, CBR1, PTGES, PTGIS, HPGDS, TBXAS1 |
| cysteine biosynthetic process | biological process | CBSL, CBS, CTH, GGT1 |
| cysteine biosynthetic process from serine | biological process | CBSL, CBS |
| cysteine biosynthetic process via cystathionine | biological process | CBSL, CBS, CTH |
| cysteine metabolic process | biological process | GCLC, CDO1, CTH |
| cysteine transport | biological process | NFE2L1 |
| cysteinyl-tRNA aminoacylation | biological process | CARS1, CARS2 |
| cytidine deamination | biological process | APOBEC3F, CDADC1, CDA, APOBEC3G, APOBEC3A, APOBEC3C, APOBEC3B, APOBEC1, APOBEC2 |
| cytidine to uridine editing | biological process | RBM47, A1CF, APOBEC3F, APOBEC3G, APOBEC3A, APOBEC3C, APOBEC3B, APOBEC1, APOBEC2 |
| cytidine transport | biological process | SLC28A1 |
| cytochrome c-heme linkage | biological process | HCCS |
| cytochrome complex assembly | biological process | COX10, CYBA |
| cytokine biosynthetic process | biological process | CEBPE, IL17F, CD28 |
| cytokine metabolic process | biological process | TNFSF15 |
| cytokine production | biological process | S100A9, CD226, NFATC1, BATF, RASGRP1, LIPA, ITK, NFATC3, MAF, NFATC2, PLA2R1, NFATC2IP, NFAT5, S100A8, PIK3CG, NFATC4, CD4, PIK3CD, KAT2A, S1PR3, PTAFR, DBH, TXK, IRAK4 |
| cytokine production involved in immune response | biological process | LACC1, NOD2, MR1, INAVA |
| cytokine production involved in inflammatory response | biological process | IDO1, SEH1L, CD96 |
| cytokine secretion | biological process | S100A12, NOX5, BTN3A1, LYN, LCP2, DYSF, AGT, S100A13 |
| cytokine secretion involved in immune response | biological process | TLR2, SPHK2, NOD2, NLRP3 |
| cytokine-mediated signaling pathway | biological process | IL1B, IL6, DCN, IL6R, TNFRSF1A, IL6ST, IFNA1, IL1A, F3, STAT3, BAD, IL5, KIT, IL17RD, FLRT3, IL1R2, LRRC4C, CX3CL1, HSPA8, CCL20, IL13RA2, NUMBL, JAK2, NDN, CCR1, CSF2RB, IL7, VCAM1, PIK3R1, SHC1, BCL6, RHOU, ZC3H15, CSF3R, FZD4, SOCS5, HSP90B1, IL1R1, IFNGR1, IRAK1, STAT5B, RPS27A, PLP2, IL20RB, IL22RA2, IRAK2, KRAS, CCL3, STX3, CTF1, ANXA1, IFNA8, IL12RB1, CCL11, BATF, IL1F10, PTPN6, IL13, IFNGR2, IL10RA, IL34, SOCS1, S1PR1, CCND1, CNTFR, IL13RA1, IL1RAP, IL20, ITGAM, GATA3, CD86, YWHAZ, RELA, IFNL1, IRAK3, CCL22, PF4, IL3, RORA, IL23R, CRLF2, IFNA10, IFNAR1, TEC, IRF5, RAPGEF1, GREM2, IL36RN, GAB2, EREG, LIFR, CNOT9, COL1A2, EPOR, JAK1, GHR, CXCL2, GRB2, TWIST1, FER, CBL, ZEB1, TRAF6, ALOX5, UBC, JUNB, MPL, OPRD1, CXCL1, UBA52, CRLF1, FOS, OSM, ITGAX, CDKN1A, STAT2, IL16, CCL19, DUOX2, IL36G, ITGB2, CSF3, IL32, BCL2L1, CD4, IL2RB, CCL3L1, IL2RG, IFNL3, EDA, IL19, PIK3CD, IFNA2, IFNA14, HCK, POU2F1, STX4, IL11RA, IL17F, OSMR, IL12RB2, FGF2, PTPRZ1, PTAFR, CRK, IL5RA, IL24, IL22RA1, IL31RA, LAMA5, FOXO3, UBB |
| cytokinesis | biological process | BRCA2, AURKC, BIRC5, 39326, NOX5 |
| cytokinetic process | biological process | ANXA11, MYH9, SPAST |
| cytolysis | biological process | BAK1, LYZ, PRF1, LYZL6, C6, GZMB, C5, MMD, GZMH, MICB, GZMA, GZMM, C8G, C7 |
| cytolysis by host of symbiont cells | biological process | CFHR1, CAMP, KRT6A, REG3G, HRG, F2, CFHR5, APOL1 |
| cytolysis in other organism | biological process | CCL28 |
| cytoplasm organization | biological process | KIF5B, TFCP2L1, RRN3, PADI6 |
| cytoplasm protein quality control by the ubiquitin-proteasome system | biological process | RNF126 |
| cytoplasmic actin-based contraction involved in cell motility | biological process | SHTN1, LIMCH1, VIL1 |
| cytoplasmic microtubule organization | biological process | CIB1, PCM1, CAMSAP1, TUBGCP4, CAMSAP2, CCDC88B, KATNA1, WDR73, DVL1, TRDN, CCDC88A, HOOK3, STMN3, HOOK2, CAV3, DST, TUBGCP3, CRIPT, TUBG1, CLIP1, CLIP4, SLK, CCDC88C, CEP126, CHP1, SLAIN2, CCDC13, TBCB, TUBGCP5, TUBGCP2, PLK3, TUBGCP6, FIGNL1, TUBG2, FSD1, CAMSAP3, CLIP2, IFT172, KATNAL2, CLIP3, SPAST |
| cytoplasmic mRNA processing body assembly | biological process | DYNC1H1, LSM3, LSM14A, PATL1, DDX6, RC3H1, EDC3, LIMD1, LSM4, ATXN2 |
| cytoplasmic pattern recognition receptor signaling pathway | biological process | ALPK1, TIFA |
| cytoplasmic pattern recognition receptor signaling pathway in response to virus | biological process | IFIH1 |
| cytoplasmic sequestering of CFTR protein | biological process | GOPC |
| cytoplasmic sequestering of NF-kappaB | biological process | IL10, PSMD10, NFKBIA, NFKBIB, G3BP2, FAF1, CCDC22 |
| cytoplasmic sequestering of protein | biological process | DZIP1, COPS9, LATS1, YWHAB, GET4 |
| cytoplasmic sequestering of transcription factor | biological process | PKD1, SRI, KEAP1, CREB3, MXI1, NFKBIE, PKD2, NFKBIA, SUFU, TONSL, MDFI |
| cytoplasmic translation | biological process | RPL31, RPL24, RPL6, RPLP0, RPL29, RPL15, RPL32, RPS21, RWDD1, DRG1, RPL11, RPL19, HSPA14, RPL35A, RPS23, RPL41, ZC3H15, RPL9, RPL30, RPL38, RPLP1, RPL39, RPL8, FTSJ1, RPL18A, RPL22, RPS29, RPL10A, RPS28, RPL36, RPL26L1, RPL22L1, RPL18, TMA7, RPSA, RPL36A, RPL17, RPL26, DRG2 |
| cytoplasmic translational initiation | biological process | EIF3H, EIF3E, EIF3D, EIF3K, EIF3L, EIF3F, EIF4A2, EIF3M, EIF3G, EIF3J, EIF2B3, EIF3A, EIF4A1, EIF3B, EIF3C, EIF3I |
| cytoplasmic translational termination | biological process | GSPT1, ETF1, GSPT2 |
| cytosine metabolic process | biological process | MAPK1, CDA |
| cytoskeletal anchoring at plasma membrane | biological process | EZR |
| cytoskeleton organization | biological process | APOE, SOX9, BRWD1, TPM1, ANK1, KISS1, MAST2, SIPA1L3, CAMSAP1, DES, DPYSL2, PALLD, ANK3, PDZD8, WASF3, ACTL7B, SVIL, DMD, RHOU, CCDC6, CNN2, MAP3K20, YEATS4, CCL3, ZMYM3, KRT84, MACF1, EPB41L3, EPB42, CCL11, PHIP, ABI2, KRT6B, CTNNA2, SPTBN1, SS18, MAEA, AJUBA, ABLIM1, KRT6A, FTCD, MDK, CYLC2, SPRYD3, DIAPH1, DST, ARAP3, PACSIN2, TLN2, MICAL3, PAK6, PLCE1, SPTBN2, PRPF40A, TUBA3C, TUBA3D, NEDD9, ACTL7A, ANK2, FGD6, MAST4, MSN, ELMO2, TNIK, CYLC1, FMNL2, KLHL20, WTIP, OBSL1, CAPZB, ZMYM4, SEMA6A, ZRANB1, CFAP410, SPTB, SPTAN1, FGD4, GAN, SIPA1, PSTPIP2, CDC42BPB, PLD2, PALM, PAK4, FGD2, LIMD1, AVIL, CCL7, ARHGAP4, DMTN, MAST1, MICAL2, ZMYM6, THY1, BRWD3, ACTL6B, CSPG5, KRT15, SH3D19, MICAL1, TSPAN32, NCKIPSD, PAK5, AGRN, MAST3, KRT13, SYNE1, GPR35, PACSIN3, ARHGAP10, CAP2, CNTNAP1, ABLIM2, SPTBN4, BIN1, ABLIM3, BFSP2, PADI6, RANBP10, FGD5, DOCK2, SH3KBP1, PACSIN1, MARK1, FMNL1, VIL1, CAP1, DIAPH3, STRIP2, CCL2, UGT8, FMNL3 |
| cytoskeleton-dependent cytokinesis | biological process | SEPTIN2, SEPTIN9, SEPTIN10, DCTN3, IST1, ROPN1B, SEPTIN11, SEPTIN1, SEPTIN5, SEPTIN8, TMEM250, BIN3, SEPTIN14, SPAST, SEPTIN3, SEPTIN7 |
| cytoskeleton-dependent intracellular transport | biological process | KIF26B, STARD9, KIF5B, KIF1C, CCDC88B, KIF14, CCDC88A, HOOK3, MAP6D1, KIF1B, HOOK2, TUBB, KIF5A, CCDC88C, MAP6, TUBA1C, MYO10, KIF1A |
| cytosol to endoplasmic reticulum transport | biological process | TAP1, TAP2 |
| cytosolic calcium ion transport | biological process | CCN2, RYR2, SLC8A1 |
| cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration | biological process | P2RY12 |
| cytosolic transport | biological process | ACTR2 |
| cytotoxic T cell degranulation | biological process | RAB27A |
| cytotoxic T cell differentiation | biological process | CD8A |
| D-alanine catabolic process | biological process | DAO |
| D-alanine transport | biological process | SLC7A10 |
| D-amino acid catabolic process | biological process | DDO |
| D-amino acid metabolic process | biological process | DAO, DDO |
| D-aspartate import across plasma membrane | biological process | SLC1A2, SLC1A3, NTSR1 |
| D-gluconate catabolic process | biological process | PGD, IDNK |
| D-gluconate metabolic process | biological process | PGD |
| D-glucuronate catabolic process | biological process | AKR1A1 |
| D-ribose catabolic process | biological process | NUDT5, RBKS |
| D-ribose metabolic process | biological process | RPIA, RBKS |
| D-serine biosynthetic process | biological process | SRR |
| D-serine catabolic process | biological process | DAO |
| D-serine metabolic process | biological process | DAO, SRR |
| D-serine transport | biological process | SFXN1, NFKBIE, SLC7A10 |
| D-xylose catabolic process | biological process | DHDH |
| D-xylose metabolic process | biological process | DCXR, XYLB |
| dADP phosphorylation | biological process | AK9 |
| dAMP biosynthetic process | biological process | DCK, DGUOK |
| dAMP phosphorylation | biological process | AK9 |
| dark adaptation | biological process | TENT2 |
| dATP biosynthetic process | biological process | ADK |
| dATP catabolic process | biological process | NUDT1, SAMHD1, ADA |
| dATP metabolic process | biological process | GUK1 |
| daunorubicin metabolic process | biological process | AKR1C3, AKR1B1, AKR7A2, AKR1A1, AKR1C2, CBR4, AKR1B10, AKR1C1, AKR1C4 |
| dCDP phosphorylation | biological process | AK9 |
| dCMP phosphorylation | biological process | AK9 |
| dCTP catabolic process | biological process | DCTPP1 |
| de novo centriole assembly involved in multi-ciliated epithelial cell differentiation | biological process | DEUP1, CEP63, CCDC78 |
| deadenylation-dependent decapping of nuclear-transcribed mRNA | biological process | PAN3, LSM1, DCP2, DCP1B, PATL1, DCP1A, DCPS |
| deadenylation-independent decapping of nuclear-transcribed mRNA | biological process | PNRC2, EDC4, DCP1B, EDC3, DCP1A |
| death-inducing signaling complex assembly | biological process | TNF, TNFRSF1A, CASP8, RAF1, FADD, TRADD, TRAF2 |
| decidualization | biological process | ESR1, VDR, LIF, PTGS2, GHRL, TPPP3, CTSV, CTSB, PTN, PPARD, SPP1, GHSR, MEN1, STC2, EPOR, CYP27B1, PTGIS, JUNB, ASH1L |
| defecation | biological process | MDK |
| defense response | biological process | TNF, INHBA, TNFRSF1A, IFNA1, HSF1, DEFB106A, DEFB126, DEFB129, CX3CL1, MALT1, NOX1, CD74, CAMLG, CD83, SP140, P2RY11, CSF3R, CYSLTR1, CXCL11, CYBB, STAT5B, TPSAB1, CAMP, KCNN4, IFNA8, DEFB103A, TAP1, CXCL6, COLEC12, FOXN1, FCGR2B, DEFA3, NOD2, EPX, GATA3, TIAL1, RELA, DEFB4A, PF4, MX1, DEFB1, DEFA5, TLR1, DEFB104A, IFNA10, CEBPE, CLEC1B, CD48, DEFB114, DEFB121, NLRP3, DEFB127, CXCL2, DEFB132, IRGM, CXCL1, LILRA2, DEFB125, RNASE6, STAT2, TNIP1, DUOX2, SOCS6, IL32, PTPRCAP, HP, MPO, DEFA4, MX2, DEFA1, MFHAS1, IFNA2, IFNA14, PPBP, CXCL3, WAS, MST1R, ACKR1, TLR3, LILRA1, IL31RA, CD84, SSC5D, LILRB5, PF4V1, LILRA3, MICU1, NOD1, ICOSLG, DUOX1, IFNW1, STAT6, STAT5A, CXCL12, CXCL10, CXCL5 |
| defense response to bacterium | biological process | TNF, IFNG, TNFRSF1A, IL10, S100A12, TLR4, LYZ, ADAMTS5, LTF, LPO, NOS2, MUC5B, EPPIN, DEFB106A, DEFB126, DEFB129, ELANE, SLPI, S100A9, CCL20, LYST, SHC1, RAB1A, BCL3, H2BC21, MYD88, PLAC8, LYZL6, ANXA3, CAMP, SLAMF8, SYK, DEFB103A, GNLY, CXCL6, COLEC12, CST11, DEFA3, NOD2, H2BC12, EPX, NAIP, DEFB4A, CTSG, DEFB1, DEFA5, GSDMB, DEFB104A, STATH, ISG15, RAB14, CEBPE, BPIFA2, DEFB114, DEFB121, STAB1, IGLL5, ANKRD17, PGLYRP4, NR1H4, DEFB127, CFP, RBPJ, DEFB132, PRKCD, NLRP1, IRGM, S100A8, DEFB125, RNASE6, RNASE3, SLC11A1, TREM2, PRG2, HAMP, IRF8, TLR9, HP, MPO, DEFA4, IGLL1, BPI, FPR2, FCER1G, SFTPD, DEFA1, LALBA, PPBP, SPN, AZU1, VGF, TLR3, CLEC4D, MBL2, WFDC12, SPON2, BPIFA1, NOD1, TLR5, LBP, GSDMD, TLR6, COCH, MAVS, STAB2, LEAP2, GSDMA, GSDMC, HTN3, RAG2, H2BC10, RNASE7, GALP |
| defense response to fungus | biological process | S100A12, IL17A, ELANE, S100A9, CLEC6A, COTL1, TSLP, GNLY, DEFA3, CTSG, DEFA5, S100A8, HAMP, MPO, DEFA4, DEFA1, HRG, SPON2, IL17RA, LEAP2, HTN3, RNASE7 |
| defense response to fungus, incompatible interaction | biological process | TGFB1 |
| defense response to Gram-negative bacterium | biological process | IL6, IL6R, ADM, IL23A, SERPINE1, TLR4, APP, B2M, NOS2, DROSHA, TAC1, OPTN, LCE3A, RPS19, RPL30, TSLP, LYZL6, CAMP, DEFB103A, CST11, NPY, RNASE2, DEFA3, H2BC12, DMBT1, DEFB4A, CTSG, DEFB1, DEFA5, IL23R, DEFB104A, SELP, DEFB114, LYZL1, LYZL2, DEFB127, DEFB132, MR1, IRGM, S100A7, RNASE6, TUSC2, RNASE3, SLC11A1, TNFRSF14, CALCA, HAMP, TLR9, ADGRB1, CD4, DEFA4, BPI, DEFA1, PYCARD, LALBA, AZU1, CD160, IL22RA1, RARRES2, SSC5D, LBP, GSDMD, LYPD8, RNASE7, GALP |
| defense response to Gram-positive bacterium | biological process | TNF, IL6, IL6R, IL12A, ADM, HLA-E, TLR2, CRP, APP, B2M, SPACA3, DROSHA, PLA2G2A, TAC1, TBK1, LCE3A, H2BC21, MYD88, LYZL6, CAMP, RPL39, DEFB103A, HAVCR2, NPY, KRT6A, RNASE2, DEFA3, H2BC12, REG3G, DMBT1, DEFB4A, CTSG, TIRAP, DEFB1, DEFA5, DEFB104A, SEH1L, GBP2, DEFB114, LYZL1, LYZL2, PGLYRP4, NLRP3, RIPK2, MR1, PLA2G1B, RNASE6, RNASE3, TNFRSF14, PGLYRP2, P2RX7, CALCA, FGR, HAMP, CARD9, DEFA4, EPHA2, DEFA1, PPP1R11, LALBA, TNFSF8, RARRES2, SSC5D, ANG, MBL2, NOD1, LBP, GSDMD, IL27RA, LTA, STAB2, CD36, C5AR1, H2BC10, RNASE7 |
| defense response to nematode | biological process | EPX, TNFSF4 |
| defense response to other organism | biological process | IL31RA |
| defense response to protozoan | biological process | IFNG, IL4, IL6, IL10, IL12A, CLEC7A, LYST, CCDC88B, BCL3, MYD88, BATF, BATF2, PF4, GBP2, SLC11A1, IRF8, DEFA1, HRAS, TSPAN32, CD40, IL4R |
| defense response to tumor cell | biological process | PRF1, RBMS3, PLK5 |
| defense response to virus | biological process | IFNG, IL6, BCL2, IL23A, IFNA1, STAT1, IL33, CD8A, PRF1, AGBL4, DDX1, TBK1, ADARB1, G3BP1, ITCH, IFIH1, POLR3F, PLA2G10, IFI44L, ZC3H12A, LYST, DHX36, OAS1, BST2, TRIM25, LSM14A, DTX3L, ADAR, APOBEC3F, ISG20, TRIM11, DDX21, IFNA8, ZC3HAV1, AEN, ZCCHC3, BNIP3L, TTC4, ILF3, NLRP9, DHX58, POLR3K, IFI6, RNASE2, DEFA3, IRF9, OASL, RSAD2, EXOSC5, IFIT1, RELA, RNASEL, FADD, SLFN11, IFNL1, DMBT1, POLR3A, FCN3, MX1, ZBP1, DDX41, POLR3H, IFNA10, ISG15, PTPRC, SERINC3, IRF5, ABCC9, AGBL5, IFITM3, BNIP3, SKP2, NLRP3, SHFL, GBP1, BECN1, FAM111A, SAMHD1, ZNF175, RIOK3, PLSCR1, IFITM1, IFI27, CXADR, IFITM2, ZMYND11, IFI16, GBP3, APOBEC3G, PML, AIMP1, DNAJC3, NCBP3, POLR3C, GPAM, EXOSC4, EXOC1, IFIT2, IRF2, APOBEC3A, PCBP2, SERINC5, ELMOD2, DDX17, RNASE6, STAT2, HYAL2, STING1, CGAS, MOV10, APOBEC3C, PQBP1, IRF1, EIF2AK2, BCL2L1, DDX60, IRF7, TRIM52, MAP3K14, CARD9, TLR9, RIPK3, MX2, DEFA1, UNC13D, IFNL3, TLR7, PYCARD, IFNA2, IFNA14, POLR3D, AZU1, TLR3, POLR3E, IL10RB, IRF3, SPON2, BPIFA1, TREX1, IFNW1, CD40, TRIM56, UNC93B1, |
| definitive erythrocyte differentiation | biological process | TGFBR3, ZFPM1 |
| definitive hemopoiesis | biological process | TGFBR3, ADAR, LYL1, BCR, MFAP5, HIPK1, CBFB, SP3, TEK, ZFP36L2, GATA2, HOXB4, MEIS1, HOXB3, HOXA9 |
| dehydroascorbic acid transport | biological process | SLC2A10, SLC2A14, SLC2A8, SLC23A1, SLC2A6 |
| delamination | biological process | AKNA |
| deltoid tuberosity development | biological process | BMP4, PITX2 |
| demethylation | biological process | CYP1A1, POR, CYP51A1, ALKBH4, MMACHC |
| dendrite arborization | biological process | PTN, PHACTR1, CHRNA7, ZNF365 |
| dendrite development | biological process | GHRL, APP, BMP7, BAIAP2, HDAC2, PPP1R9B, FLRT1, TULP1, MCF2, SLC25A46, IGSF9, NTN1, LAMC2, BBS4, GRIP1, KLHL1, STRN, CD3E, MAP2, MECP2, MAP1S, PRKG1, SS18L1, LST1, TMEFF1, GRIN3A, TRAPPC4, PAK3, EGFLAM, CRK, TMEFF2, NRP1, ACTL6B, NTN5, AGRN, NTN3, SCARF1, CRKL, MAP1B, RELN |
| dendrite extension | biological process | LLPH, AUTS2, SH3GL2, CDKL3, CYFIP2, TMEM108, CYFIP1, WASF1, SLC9A6 |
| dendrite morphogenesis | biological process | ITGB1, SEMA3A, MEF2A, RBFOX2, BTBD3, TRAK2, ABITRAM, RERE, DVL1, PREX2, SDC2, CTNNA2, VLDLR, PICALM, DCDC2, SLITRK5, DTNBP1, TRAK1, CELSR2, KIDINS220, MAP2, FARP1, ABI1, HPRT1, MAP6, DCLK1, DSCAM, TMEM106B, KLF7, CDK5, LRP4, MAPK8IP2, MINK1 |
| dendrite regeneration | biological process | FAS, PTN, MATN2 |
| dendrite self-avoidance | biological process | CNTN4, PALLD, TNN, NPTN, NEXN, ROBO4, IGSF9, CNTN2, MYPN, DSCAM, VSTM2L, EMB, CNTN6, ROBO3 |
| dendritic cell chemotaxis | biological process | CCL5, CCR5, CXCR4, CCR1, GPR183, ANO6, HMGB1, CXCR2, CCR6, PIK3CG, CCL19, CXCR1, CCR7, TRPM4, TRPM2, CCL21 |
| dendritic cell cytokine production | biological process | KIT |
| dendritic cell dendrite assembly | biological process | ARID1B, CCL21 |
| dendritic cell differentiation | biological process | IL4, AXL, GAS6, BATF3, LYN, TREM2, TRPM2, GATA1 |
| dendritic cell homeostasis | biological process | GPR183 |
| dendritic cell migration | biological process | CDC42, EPS8, DOCK8, ALOX5, NLRP12 |
| dendritic cell proliferation | biological process | TBK1 |
| dendritic spine development | biological process | ARF4, EPHB2, ARID1B, NCK2, EPHB1, IQSEC1, SRGAP2, ACSL4, UBA6, PAK3, PAK4, SLC9A6, SLC12A5, EPHB3, CAMK2A |
| dendritic spine maintenance | biological process | PICK1, PRNP, CTTN, ITPKA, ITGA3, TANC1 |
| dendritic spine morphogenesis | biological process | PTEN, DVL1, EPHB2, EPHB1, SHANK2, CTNND2, DLG4, HDAC6, PAK3, EPHB3, SHANK1, WNT7A, ZNF365, DOCK10 |
| dendritic spine organization | biological process | PICK1, LGMN, ARF1, CHRNA7 |
| dendritic transport of messenger ribonucleoprotein complex | biological process | HNRNPU, SFPQ, PURA |
| dendritic transport of mitochondrion | biological process | TRAK2, WASF1 |
| dense core granule cytoskeletal transport | biological process | TANC2, PPFIA2, KIF1A |
| dense core granule exocytosis | biological process | CADPS, CADPS2 |
| dense core granule maturation | biological process | SNX19, BAIAP3 |
| dense core granule priming | biological process | UNC13C, UNC13B, UNC13A |
| dentate gyrus development | biological process | PTEN, NEUROD6, MDK, BTG2, EMX2, SMO, NEUROD1, CDK6, TMEM108, LEF1, DRD1, LMX1A, PROX1 |
| dentin mineralization | biological process | TCIRG1 |
| dentinogenesis | biological process | FAM20C, SMPD3, HTRA1, SLC34A1 |
| deoxyadenosine catabolic process | biological process | ADA |
| deoxycytidine metabolic process | biological process | TK2 |
| deoxynucleotide transport | biological process | SLC25A19 |
| deoxyribonucleoside catabolic process | biological process | DERA |
| deoxyribonucleoside monophosphate biosynthetic process | biological process | DCK, DGUOK, TK2, TK1 |
| deoxyribonucleoside monophosphate catabolic process | biological process | DNPH1 |
| deoxyribonucleoside triphosphate catabolic process | biological process | ITPA |
| deoxyribonucleoside triphosphate metabolic process | biological process | RRM2B |
| deoxyribonucleotide biosynthetic process | biological process | RRM2, RRM2B, RRM1 |
| deoxyribonucleotide catabolic process | biological process | DERA, NT5C, SAMHD1, NT5M |
| deoxyribonucleotide metabolic process | biological process | RRM2 |
| deoxyribose phosphate catabolic process | biological process | DERA, PGM2 |
| dephosphorylation | biological process | PON1, PTEN, G6PC3, EPHX2, PTPN11, DUSP6, ACPP, PGAM1, PPIP5K1, PGAM4, PTPRJ, PTPDC1, INPP4B, ALPP, CDKN3, RNGTT, TPTE, MTM1, NT5DC1, DUSP13, PXYLP1, ENOPH1, DUSP11, ALPI, PTPRR, MDP1, DUSP22, MTMR6, ACP2, DUSP8, DUSP19, NT5C3B, DUSP15, PTPRF, APTX, NTPCR, MTMR4, PTPRA, PTPN23, ACP6, PPP3CB, PTPN2, HDHD2, PTPN6, HDDC2, NT5C1A, FBP1, NT5C, PTP4A1, LHPP, DUSP21, NT5E, PTPRG, LPIN1, DUSP27, MTMR8, PTPRT, PFKFB2, DUSP14, PSPH, PTPN20, PTPN22, PTPRC, DUSP5, NUDT16, INPP4A, MINPP1, PTPN13, SSH2, PHOSPHO1, PTPRB, PTPN9, ATP1A2, CDC14B, PTPRM, PPP3CA, PHOSPHO2, PTPMT1, PTPRN2, INPP5K, ARMT1, MTMR1, DUSP18, NT5C1B, PGP, DUSP28, NANP, SSH3, PTPRU, PTPN1, PTPRE, PPM1A, LPIN2, CTDSPL, DUSP1, PUDP, MTMR3, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, FBP2, PTPN5, SSH1, ATP1A1, CA3, PTPRS, PTPN14, PFKFB4, PRUNE1, THNSL2, CILP2, PGAM5, TIGAR, CILP, PTPRZ1, PTPN12, PTPN18, PTPRH, PTPN4, NT5C2, DUSP9, DUSP16, ALPL, DUPD1, ACP7, PDXP, NT5M, LPIN3, THTPA, DUSP26, NT5DC2, PTPRD, PTPN3, MTMR14, DUSP2, TPTE2, G6PC2, MTMR7, DUSP10 |
| dephosphorylation of RNA polymerase II C-terminal domain | biological process | SSU72, RPRD1A, RPRD1B, CTDP1 |
| depurination | biological process | OGG1, MPG, MUTYH |
| depyrimidination | biological process | OGG1, NEIL1, TDG, NEIL2, NTHL1, MBD4, SMUG1, UNG |
| dermatan sulfate biosynthetic process | biological process | DCN, DSE, CHST12, CSPG4, BCAN, DSEL, BGN, CHST14, CSPG5, NCAN, UST |
| dermatan sulfate catabolic process | biological process | IDUA |
| dermatan sulfate metabolic process | biological process | DSE, DSEL |
| dermatan sulfate proteoglycan biosynthetic process | biological process | CSGALNACT1, B3GAT3, CSGALNACT2 |
| dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | biological process | CSGALNACT2 |
| dermatan sulfate proteoglycan metabolic process | biological process | CHST14 |
| descending aorta development | biological process | LOX |
| desensitization of G protein-coupled receptor signaling pathway | biological process | GRK4, GRK2, GIPR |
| desensitization of G protein-coupled receptor signaling pathway by arrestin | biological process | ADRB2, ADRB3, ARRB2 |
| desmosome assembly | biological process | PKP2, JUP, PKP3 |
| desmosome organization | biological process | DSP, PERP, GRHL1, PKP2, DSG2, NECTIN1 |
| detection of abiotic stimulus | biological process | TAC1, TIMELESS, NPFFR2 |
| detection of bacterial lipoprotein | biological process | SSC5D |
| detection of bacterium | biological process | HLA-DRB1, HLA-A, NOD2, NAIP, PGLYRP4, PGLYRP2, NOD1 |
| detection of biotic stimulus | biological process | NOD2, NLRP3, NOD1 |
| detection of calcium ion | biological process | KCNMB1, KCNMB3, CASQ2, RYR2, SYT1, CALM1, CALM2, CALM3, ASPH, KCNIP2, KCNMB4, STIM1 |
| detection of chemical stimulus | biological process | UGT2A1 |
| detection of chemical stimulus involved in sensory perception | biological process | OR5AR1, ASIC3 |
| detection of chemical stimulus involved in sensory perception of bitter taste | biological process | LPO, TAS2R38, PIP, AZGP1, RTP5, TAS2R9, CST2, TAS2R19, TAS2R50, GNAT2, TAS2R60, TAS2R8, PIGR, RTP3, TAS2R1, CST4, RTP1, TAS2R39 |
| detection of chemical stimulus involved in sensory perception of pain | biological process | TRPA1, ASIC3, TRPV1 |
| detection of chemical stimulus involved in sensory perception of smell | biological process | OR2W3, OR12D2, OR2AG2, OR10AD1, OR5AR1, OR52D1, OR5V1, OR9A4, OR51A7, OR1G1, OR9Q2, OR51V1, OR52A1, OR1L6, OR1N2, OR6B3, OR10J1, OR1D5, OR10A3, OR2T33, OR52E4, OR2H1, OR2J2, OR56A4, OR10Q1, OR13C4, OR2T4, OR4X1, OR5P2, OR2M4, OR4C12, OR5B21, OR5F1, OR5I1, OR2L13, OR4D11, OR8D4, OR13A1, OR13C8, OR5R1, OR5K1, OR52B2, OR51B6, OR51B5, OR2S2, OR7C2, OR3A1, OR10A4, OR2A4, OR1E1, OR2W1, OR10H1, OR7C1, OR2A14, OR10A5, OR51I2, OR10H2, OR5C1, OR2T1, OR1C1, OR8G1, OR9Q1, OR1F1, OR2Z1, OR2T6, OR5AC2, OR6C68, OR4K17, OR5T2, OR5P3, OR8D2 |
| detection of chemical stimulus involved in sensory perception of sour taste | biological process | PKD2L1 |
| detection of chemical stimulus involved in sensory perception of sweet taste | biological process | TAS1R2, TAS1R3 |
| detection of chemical stimulus involved in sensory perception of taste | biological process | PKD2L1, TAS1R1 |
| detection of cold stimulus involved in thermoception | biological process | GRIK2 |
| detection of diacyl bacterial lipopeptide | biological process | TLR2, TLR6 |
| detection of DNA damage stimulus involved in DNA damage checkpoint | biological process | TREX1 |
| detection of fungus | biological process | TLR4 |
| detection of glucose | biological process | PDX1, GCK |
| detection of gravity | biological process | OTOP1 |
| detection of hot stimulus involved in thermoception | biological process | WDR47 |
| detection of hypoxia | biological process | TGFB3, ENG |
| detection of hypoxic conditions in blood by carotid body chemoreceptor signaling | biological process | P2RX2 |
| detection of light stimulus | biological process | PDE6B, RHO, OPN3 |
| detection of light stimulus involved in visual perception | biological process | TULP1, CCDC66, GNAT2, GUCY2F, REEP6, ATP8A2, CRB1, CEP250, GRM6, CNGB1, CACNA2D4, EYS, RPE65, RGS9BP |
| detection of lipopolysaccharide | biological process | TLR4, LY96, SCARB1, TREM2 |
| detection of lipoteichoic acid | biological process | TREM2 |
| detection of mechanical stimulus | biological process | PKD1, TCAP, PKDREJ, PKD2, PKD2L1, PIEZO2, JUP, PKD1L2, PIEZO1 |
| detection of mechanical stimulus involved in sensory perception | biological process | IGF1, ASIC2, PIEZO2, LHFPL5, ASIC3 |
| detection of mechanical stimulus involved in sensory perception of pain | biological process | NTRK1, CXCR4, TMEM120A, TRPA1, ITGA2, SCN1A, BACE1, CACNB3, KCNA1, CXCL12, ASIC3 |
| detection of mechanical stimulus involved in sensory perception of sound | biological process | STRC, KIT, COL11A1, MKKS, REST, HPN, CHRNA10, ADGRV1, TMC1, LHFPL5, WHRN, PDZD7, TMC2 |
| detection of mechanical stimulus involved in sensory perception of touch | biological process | KCNK4, KCNA1 |
| detection of molecule of bacterial origin | biological process | LBP |
| detection of muramyl dipeptide | biological process | NOD2 |
| detection of muscle stretch | biological process | TCAP, CAV3, TTN, CSRP3 |
| detection of nodal flow | biological process | PKD2 |
| detection of oxidative stress | biological process | ADIPOQ |
| detection of oxygen | biological process | CYB5R4 |
| detection of peptidoglycan | biological process | TREM2 |
| detection of stimulus | biological process | CRTAM |
| detection of stimulus involved in cell cycle checkpoint | biological process | TREX1 |
| detection of stimulus involved in sensory perception | biological process | PPEF2, PPEF1 |
| detection of temperature stimulus | biological process | TRPM3, NGFR |
| detection of temperature stimulus involved in sensory perception | biological process | ASIC3 |
| detection of temperature stimulus involved in sensory perception of pain | biological process | NTRK1, CXCR4, EPHB1, NR2F6, TAC4, PRDM12, CALCA, LXN, NTSR1, ARRB2, ANO1, CXCL12, ASIC3, TRPV1 |
| detection of temperature stimulus involved in thermoception | biological process | TRPV1 |
| detection of triacyl bacterial lipopeptide | biological process | TLR2, TLR1 |
| detection of tumor cell | biological process | CRTAM |
| detection of virus | biological process | IFIH1, ZCCHC3, SERINC3, SERINC5, TLR3 |
| detection of visible light | biological process | OPN5, ELOVL4, GPR88, GRM6, OPN4, OPN3 |
| detection of wounding | biological process | FOXF1 |
| determination of adult lifespan | biological process | TP53, ATM, MSH2, ZMPSTE24, PRDM2, IDE, TFCP2L1, MSH6, GHRHR, CGAS, TREX1, INPP5D, LRRK2, RAD54L, COQ7 |
| determination of affect | biological process | SHANK1 |
| determination of bilateral symmetry | biological process | ALDH1A2 |
| determination of digestive tract left/right asymmetry | biological process | CCDC103, DNAAF1, MEGF8, ZIC3, CCDC40 |
| determination of dorsal identity | biological process | CER1, WNT8B, GREM2, NBL1, GREM1 |
| determination of heart left/right asymmetry | biological process | CER1, MEGF8, MMP21, DAND5, HAND2 |
| determination of intestine left/right asymmetry | biological process | NPHP3 |
| determination of left/right asymmetry in lateral mesoderm | biological process | SHH, SMO, DAND5 |
| determination of left/right asymmetry in nervous system | biological process | ZIC3 |
| determination of left/right symmetry | biological process | NODAL, FGF8, SHH, KIF3B, DYNC2H1, DNAH5, DNAH11, DNAI1, ARMC4, ALG5, NEK8, FOXJ1, IFT74, DPCD, CFAP53, IFT52, TDGF1, RFX3, DYNC2LI1, ACVR1, NKX3-2, MKKS, NOTCH1, WNT3A, ACVR2B, ARL6, PKD2, DNAAF4, ARL13B, RTTN, MEGF8, SMO, PCSK6, DNAI2, TBC1D32, SUFU, LEFTY1, CFC1B, C9orf116, CITED2, ACVR2A, AP1B1, NPHP3, MMP21, GALNT11, STIL, DAAM2, DRC1, GAS8, FOXF1, DAND5, DLL1, ZIC3, PSKH1, CC2D2A, IFT172, FOXH1, RPGRIP1L, FGF10, PITX2 |
| determination of liver left/right asymmetry | biological process | DNAAF1, PKD2, NPHP3, ZIC3, CCDC40 |
| determination of pancreatic left/right asymmetry | biological process | DNAAF1, NPHP3, ZIC3, CCDC40 |
| determination of stomach left/right asymmetry | biological process | NPHP3 |
| determination of ventral identity | biological process | AIDA |
| detoxification of cadmium ion | biological process | SLC30A1 |
| detoxification of copper ion | biological process | PARK7, MT1A, MT1F, MT1HL1, MT1G, MT1M, MT1H, ATP7A, MT2A, MT1E, MT1X, MT3, MT1B |
| detoxification of mercury ion | biological process | PARK7 |
| detoxification of nitrogen compound | biological process | MTARC2, MTARC1 |
| development involved in symbiotic interaction | biological process | NEDD4 |
| development of primary female sexual characteristics | biological process | LHFPL2, ACVR1B, DACH1, ADCYAP1R1, DACH2 |
| development of primary male sexual characteristics | biological process | LHFPL2, SFRP2 |
| development of primary sexual characteristics | biological process | CBX2 |
| development of secondary female sexual characteristics | biological process | STAT5B, IRF2BPL |
| development of secondary male sexual characteristics | biological process | STAT5B |
| development of secondary sexual characteristics | biological process | BAX, B4GALT1 |
| developmental cell growth | biological process | ARIH2, PRMT2 |
| developmental growth | biological process | BCL2, ADM, SOX10, GNAS, SHH, PYGO2, GLI3, TYMS, SMAD4, ZMIZ1, BMPR1A, ASPM, GAS1, PSAP, GATA3, SMO, NIPBL, SMAD2, KDF1, DMBX1, SRF, HOXA11, ALKBH1, GLI2, STRA6, SMAD3, CHST11, EIF4H |
| developmental growth involved in morphogenesis | biological process | WNT7B, TBX2 |
| developmental induction | biological process | NKX2-1 |
| developmental maturation | biological process | MAP1B |
| developmental pigmentation | biological process | BCL2, ZEB2, KIT, BCL2L11, MYO5A, SLC45A2, EDNRB, GNA11, OCA2, DCT |
| developmental process | biological process | CYP1A1, COMT, TP63, MKKS, NUDCD2, COLEC11, HMGB1, TTPA, SLC7A6OS, LRTOMT, ROGDI, IL11RA, NUDC, NUDCD3, NSRP1, PLVAP, RPGRIP1L |
| developmental process involved in reproduction | biological process | DMRT1, CSF1, PPP1R9B, ALPL |
| dGDP biosynthetic process | biological process | GUK1 |
| dGDP phosphorylation | biological process | AK9 |
| dGMP metabolic process | biological process | GUK1 |
| dGTP catabolic process | biological process | NUDT15, NUDT1, SAMHD1 |
| dGTP metabolic process | biological process | DGUOK |
| diacylglycerol biosynthetic process | biological process | MOGAT1, DGAT2, PLCE1, PLA2G15, MOGAT2, ANG |
| diacylglycerol catabolic process | biological process | LIPE, DAGLB, DAGLA |
| diacylglycerol metabolic process | biological process | DGKK, DGKE, DGKB, DGAT2, DGKI, DGKA, DGKG, DGKZ, DGAT1, PGS1, DGKH, DGKQ, DGKD |
| diadenosine hexaphosphate catabolic process | biological process | NUDT4, NUDT3 |
| diadenosine pentaphosphate catabolic process | biological process | NUDT4, NUDT3 |
| diadenosine polyphosphate catabolic process | biological process | NUDT3 |
| diadenosine tetraphosphate biosynthetic process | biological process | KARS1, GARS1 |
| diadenosine triphosphate catabolic process | biological process | FHIT |
| diapedesis | biological process | ITGA4, CD99L2, FER, PECAM1 |
| diaphragm contraction | biological process | GAA |
| diaphragm development | biological process | WT1, KCNAB1, ASS1, BASP1, STRA6 |
| dibasic protein processing | biological process | FURIN |
| dibenzo-p-dioxin catabolic process | biological process | CYP1A1 |
| dibenzo-p-dioxin metabolic process | biological process | CYP1A1, SRD5A2, CYP17A1, CYP1A2, CCL5, STAR |
| dicarboxylic acid catabolic process | biological process | ACOT4 |
| dicarboxylic acid metabolic process | biological process | GRHPR, GOT1, GOT2, ACOT4 |
| dicarboxylic acid transport | biological process | SLC13A3, SLC13A1, SLC25A10, SLC1A7 |
| dichotomous subdivision of terminal units involved in lung branching | biological process | CTSH |
| dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis | biological process | AREG |
| dichotomous subdivision of terminal units involved in salivary gland branching | biological process | SEMA3A, PLXNA1, SEMA3C, NRP1, PLXND1 |
| diencephalon development | biological process | SIX3, SEMA5A |
| diencephalon morphogenesis | biological process | OTX1 |
| diet induced thermogenesis | biological process | OMA1, ADRB2, UCP1, SORL1, APPL2, ADRB1, SCT, SCTR, TRPV1 |
| digestion | biological process | SULT2A1, PIR, ALPI, PGC, AKR1C2, PPARGC1A, CLPS, PRSS3, CAPN9, CCK, SST, GUCA2B, UCN3, UCN2, PGA5, CTRB1, AKR1D1, GUCA2A, AKR1C1, GKN1, LRCOL1 |
| digestive system development | biological process | NODAL, WDR19, NKX3-2, HIP1R |
| digestive tract development | biological process | TGFB1, CYP1A1, TGFB3, CCNB1, FGFR2, RB1, KIT, ITGA6, OXTR, PKD1, COBL, NKX2-2, LGR4, DCHS1, COL3A1, CLMP, NKX2-3, PDX1, CLDN18, MIXL1, SMO, NIPBL, MYOCD, SLC4A2, ALX4, TGFBR2, FOXF1, PDGFC, HRH2, CHD8, FGF10 |
| digestive tract morphogenesis | biological process | EGFR, BCL2, SOX10, HIF1A, NODAL, SHH, AGR2, VANGL2, GLI1, SFRP2, EPHB3, STRA6 |
| dihydrobiopterin metabolic process | biological process | QDPR, GCH1 |
| dihydrofolate metabolic process | biological process | ATIC, DHFR2, DHFR |
| dimethylallyl diphosphate biosynthetic process | biological process | IDI1 |
| dipeptide import across plasma membrane | biological process | SLC15A2, SLC15A1 |
| dipeptide transport | biological process | SLC15A2 |
| diphosphate metabolic process | biological process | PPA2, PPA1 |
| diphosphoinositol polyphosphate catabolic process | biological process | NUDT3 |
| diphosphoinositol polyphosphate metabolic process | biological process | NUDT4, NUDT3 |
| directional locomotion | biological process | GRIN2C, GRIN2A |
| disaccharide metabolic process | biological process | IDUA |
| distal tubule development | biological process | NOTCH1, JAG1 |
| distal tubule morphogenesis | biological process | WNK4 |
| diterpenoid metabolic process | biological process | SRD5A1, STAR, CRH |
| dITP catabolic process | biological process | NUDT16 |
| divalent inorganic cation transport | biological process | ATP7B, ATP7A, SLC40A1 |
| divalent metal ion export | biological process | SLC11A1 |
| divalent metal ion transport | biological process | SLC41A1 |
| division septum assembly | biological process | BIN3 |
| DN2 thymocyte differentiation | biological process | PTPRC, CCR6 |
| DN3 thymocyte differentiation | biological process | CCR6 |
| DNA ADP-ribosylation | biological process | PARP3 |
| DNA biosynthetic process | biological process | LIG4, TERT, POLQ, POLG, CCN2, REV1, TYMS, POLH, POLE3, POLK, POLG2, CENPF, SMPD3, LOX, POLD2, POLI, TENT4B, LIG1, POLE4, CHRAC1, HROB, LIG3, POLE, TK2, POLB, LIN9, POLL, POLD1, DNTT, TK1 |
| DNA catabolic process | biological process | DFFB, DNASE2, DNASE1L3, DNASE1, TREX1, DNASE1L1 |
| DNA catabolic process, endonucleolytic | biological process | SPO11, MUS81, REXO4, ENDOG, FBH1, DNASE2, DNASE1L3, DNASE1, DNASE1L1, EXOG |
| DNA catabolic process, exonucleolytic | biological process | ISG20, AEN, XRN2, REXO4, ERI1, ERI3 |
| DNA clamp unloading | biological process | ATAD5, RFC1 |
| DNA conformation change | biological process | ABL1, HHEX |
| DNA cytosine deamination | biological process | APOBEC3F, CDADC1, APOBEC3G, APOBEC3A, APOBEC3C, APOBEC3B, APOBEC1 |
| DNA damage checkpoint | biological process | E2F1, ATM, ATR, H2AFX, PTPN11, CLOCK, NBN, MAPK14, TIPIN, INTS7, MAP3K20, ERCC6, USP28, RAD17, RAD9B, DOT1L, RAD9A, RAD1, TIPRL, CEP63, HUS1, PEA15, CLSPN, FBXO6, TP53BP1, HUS1B, BRIP1, HINFP, ATRIP, RHNO1, DONSON |
| DNA damage induced protein phosphorylation | biological process | MAPK3, ATM, ABL1, CRY1, MAP2K6, MAPK12 |
| DNA damage response, detection of DNA damage | biological process | USP1, UBE2B, PARP1, PCNA, MRPS35, MRPS11, MRPS9, RPA2, RFC4, NEK1, RFC5, RFC3, RPS27A, RPS3, DTL, RPA1, MRPS26, HMGA2, POLD2, UBC, RPA3, WDR48, UBA52, SOX4, CFAP410, RFC2, RBX1, POLD4, UBB, POLD1, RAD18, RFC1, DDB1 |
| DNA damage response, signal transduction by p53 class mediator | biological process | TP53, MIF, NBN, BCL3, ATRX, BATF, MDM4, MYO6, TRIAP1, E2F7, NDRG1, USP10, SESN2, FOXO3, PAXIP1, ACER2 |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | biological process | TP53, BAX, CDK1, CCNB1, CDC25C, MDM2, E2F1, ATM, PLAGL1, MUC1, PCNA, PCBP4, RBL2, TFDP1, E2F4, PLK2, CNOT1, CNOT4, CARM1, ZNF385A, CNOT8, PPP2R5C, MDM4, CNOT10, GADD45A, CASP2, BTG2, GML, CNOT9, TRIAP1, EP300, ARID3A, CDKN1B, SFN, PML, TFDP2, CNOT6L, CNOT2, SOX4, RGCC, GTSE1, CDKN1A, E2F7, PRMT1, E2F8, PIDD1, RPL26, PLK3, CNOT3, RBM38, CRADD, TNKS1BP1 |
| DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | TP53, BRCA1, BRCA2, MUC1, TP63, FOXM1, RPS27L, SP100, KAT5, HIPK2, CDKN1A, RBM38, TFAP4, ING4 |
| DNA damage response, signal transduction resulting in transcription | biological process | MAD2L2 |
| DNA dealkylation involved in DNA repair | biological process | MGMT, MPG, ASCC3, ALKBH3, ALKBH1, ASCC2, ALKBH5, ASCC1 |
| DNA deamination | biological process | EXOSC5, EXOSC3, EXOSC4, EXOSC6 |
| DNA demethylation | biological process | APEX1, APOBEC3F, TDG, TET3, APOBEC3G, TET1, APOBEC3A, APOBEC3C, ALKBH4, ALKBH1, TET2, APOBEC3B, APOBEC1, APOBEC2 |
| DNA demethylation of male pronucleus | biological process | TET3, STPG4 |
| DNA double-strand break processing | biological process | BRCA1, ATM, NBN, RBBP8, UBE2N, MRE11, KAT5, UBE2V2, RAD50, EXD2, BLM, BARD1, SMARCAD1 |
| DNA double-strand break processing involved in repair via single-strand annealing | biological process | RBBP8, SLX1A, SLX4, RNF138, RAD52 |
| DNA duplex unwinding | biological process | CHD2, NBN, MCM3, HELQ, DDX1, MCM8, DDX3X, G3BP1, XRCC5, RFC4, SUPV3L1, DHX36, RFC5, RFC3, ATRX, RECQL5, ERCC6, SETX, MCM9, RUVBL2, ANXA1, POT1, ASCC3, RECQL, ERCC8, DSCC1, XRCC6, NAV2, RTEL1, MRE11, CHD5, SMARCAL1, CHD9, MCM5, CHD4, ZRANB3, RUVBL1, CHTF8, FBH1, GTF2F2, RAD50, WRNIP1, RFC2, BLM, CHD6, SMARCAD1, BRIP1, GINS2, RECQL4, DDX11, CHD3, HELB, CHD8, TREX1, CHTF18, IGHMBP2, RAD18, RAD54L2, RAD54B |
| DNA endoreduplication | biological process | ZPR1 |
| DNA geometric change | biological process | MTERF1, HMGB3, HMGB1 |
| DNA hypermethylation | biological process | DNMT1, MORC1 |
| DNA integration | biological process | GIN1, SMARCB1, THAP9, ZBED9, RLF |
| DNA ligation | biological process | LIG4, MGMT, TOP2A, APTX, XRCC6, LIG1, LIG3 |
| DNA ligation involved in DNA recombination | biological process | LIG4 |
| DNA ligation involved in DNA repair | biological process | LIG4, PARP1, PARP2, HMGB1, XRCC4, LIG1, LIG3, PAXX |
| DNA metabolic process | biological process | SPO11, POLG, TOP2A, DMC1, KPNA2, TATDN1, ERI2, RECQL5, DNASE2B, PLD4, TOPBP1, NT5E, ERI1, MYO18A, SMARCAL1, TEFM, RAN, MAP1S, TOP2B, DNASE2, DNASE1L3, MMS19, TATDN2, NME1, TREX1, PLD3, DNTT, DNASE1L1 |
| DNA methylation | biological process | GNAS, DNMT3L, MGMT, DNMT1, EZH2, DNMT3B, MTRR, MTA2, ATRX, DMAP1, EHMT2, GATAD2A, EHMT1, BAZ2A, ATF7IP, KMT2E, FOS, HEMK1, HELLS |
| DNA methylation involved in embryo development | biological process | PICK1 |
| DNA methylation involved in gamete generation | biological process | CTCFL, PIWIL2, DDX4, PICK1, PIWIL4, TDRD9, MAEL, MOV10L1, FKBP6, TDRKH, MORC1, TDRD12, KDM1B, PRMT7, TDRD1 |
| DNA methylation on adenine | biological process | N6AMT1, METTL4 |
| DNA methylation on cytosine | biological process | DNMT1 |
| DNA methylation on cytosine within a CG sequence | biological process | DNMT1, DNMT3B |
| DNA modification | biological process | TREX1, DNTT |
| DNA packaging | biological process | PRM1, PRM2, ASH1L, HAT1, NAA10, KAT6A |
| DNA protection | biological process | CBS, NUDT15, GLRX2, DCTPP1, NUDT1 |
| DNA recombinase assembly | biological process | DMC1, RAD52, SWI5 |
| DNA recombination | biological process | RAG1, BRCA1, LIG4, BRCA2, ERCC1, H2AFX, APEX1, MND1, XRCC2, KIN, NSMCE2, MORF4L1, ACTL6A, XRCC5, RPA2, SWSAP1, SUPV3L1, SLX1A, RAD51C, SFPQ, HMGB3, RECQL5, SETX, SMC5, NSMCE4A, RUVBL2, RPA1, SLX4, APEX2, INO80C, MUS81, DCLRE1C, RECQL, ENDOG, PSMC3IP, EXO1, XRCC6, NONO, INO80B, RTEL1, HMGB1, RAD52, MRE11, NFRKB, RAD21, YY1, PRKDC, TSN, THAP9, RUVBL1, XRCC4, NSMCE3, RPA3, INO80D, NSMCE1, PAGR1, REC114, PALB2, RAD50, RAD51B, RAD51D, LIG1, BLM, MCRS1, SIX6OS1, HROB, LIG3, RECQL4, INO80E, HDAC10, RAD51AP1, UCHL5, TFPT, TREX1, INO80, EME2, XRCC3, IGHMBP2, SPIDR, PAXIP1, ANKRD31, RAD54L, ACTR5, RAG2 |
| DNA repair | biological process | BRCA1, LIG4, BRCA2, OGG1, USP1, CDK1, ERCC1, MGMT, ERCC2, XRCC1, XPA, UBE2B, ATM, POLQ, PARP1, MTOR, RAD23A, RAD23B, MLH1, PMS2, ATR, TEX15, XAB2, PARP2, MLH3, HSPA1A, PCNA, H2AFX, APEX1, CDK9, SUMO1, XPC, RNF8, PRMT6, NBN, MPG, MSH2, FOXM1, KIAA0101, FANCA, XRCC2, UBE2D3, GTF2H3, DMC1, SLF2, ANKLE1, HELQ, UBE2W, USP47, RBBP8, BCCIP, REV1, MCM8, FAN1, REV3L, KIN, UBR5, NPM1, CETN2, TRIP12, MORF4L2, EPC2, NEIL1, NSMCE2, UIMC1, EXO5, MORF4L1, POLH, SUPT16H, ACTL6A, XRCC5, RPA2, RFC4, FEN1, CDK7, SWSAP1, RNF168, SLX1A, FAAP24, PARPBP, PRPF19, USP3, PSMD14, AP5Z1, RAD51C, SFPQ, PMS1, HUWE1, DTX3L, FZR1, ZMPSTE24, RFC5, RFC3, ATRX, CSNK1E, UBE2N, APTX, FANCD2, AP5S1, SMC3, RECQL5, RPS3, ERCC6, KMT5B, RRM2B, SETX, SHLD2, CHD1L, SMC5, JMY, DDB2, USP28, DMAP1, FANCF, MCM9, NSMCE4A, RUVBL2, RPA1, FAAP20, SLX4, ENDOV, RNF138, MGME1, POLK, APEX2, BACH1, UVSSA, INO80C, USP51, EMSY, ASCC3, UPF1, MUS81, DCLRE1C, BABAM1, STUB1, ERCC5, RECQL, ERCC8, TDG, RFWD3, TOPBP1, NEIL2, WRAP53, FANCL, BABAM2, POLG2, EXO1, FANCG, XRCC6, |
| DNA replication | biological process | EGF, BRCA1, LIG4, CDK1, CDC25A, CDC25C, ATM, POLQ, KAT7, IGF1, POLG, ATR, CDC7, PCNA, STRA8, SIN3A, LRWD1, NBN, TOP1, KIAA0101, MCM3, NASP, RBBP8, REV1, MCM8, ORC5, REV3L, KIN, PRIM2, SSBP1, TBRG1, TIPIN, DBF4, POLH, SUPT16H, RPA2, RBMS1, RFC4, FEN1, NAP1L1, GINS1, RBBP7, GINS3, RRM2, POLE3, RFC5, RFC3, TNFAIP1, RECQL5, RRM2B, RBBP6, KCTD13, MCM9, DTL, RPA1, SLX4, POLK, NFIB, ORC1, CCDC88A, DTD1, UPF1, NFIX, TOPBP1, DSCC1, ORC3, POLG2, EXO1, CDC45, NFIA, ORC2, TIMELESS, RAD17, CDC6, RTEL1, NFIC, MRE11, RAD9B, RAD9A, RAD1, RBBP4, KAT5, DNAJC2, RRM1, DUT, MCM5, POLD2, FAM111A, SAMHD1, ORC4, HUS1, SDE2, POLI, CHTF8, RPA3, CINP, CLSPN, RAD50, WRNIP1, LIG1, RFC2, BLM, E4F1, BARD1, GRWD1, RNASEH2A, MCM4, MCM7, PRIM1, SSRP1, STN1, LIG3, POLE, POLA2, MCM6, MCMBP, BRIP1, POLD4, GINS2, RECQL4, POLB, SET, DDX11, CHAF1A, HELB, TREX1, POLL, POLD1, NT5M, MCM10, CHTF18, ATRIP, ING5, RHNO1, IGHMBP2, MCM2, POLN, ING4, RFC1, TOP1MT, RMI1, DONSON, POLA1 |
| DNA replication checkpoint | biological process | TIPIN, CDC45, TIMELESS, RAD17, CDC6, RAD9B, RAD9A, CLSPN |
| DNA replication initiation | biological process | CDC7, LRWD1, MCM3, ORC5, PRIM2, POLE3, PURA, ORC1, TOPBP1, ORC3, CDC45, ORC2, CDC6, CCNE1, MCM5, ORC4, CDC34, POLE4, MCM4, MCM7, PRIM1, POLE, POLA2, MCM6, CCNE2, MCM10, MCM2, POLA1, MCMDC2 |
| DNA replication proofreading | biological process | POLE, POLD1 |
| DNA replication, removal of RNA primer | biological process | FEN1, RNASEH2A, RNASEH1 |
| DNA replication, synthesis of RNA primer | biological process | PRIM2, PRIM1, HELB, PRIMPOL, POLA1 |
| DNA replication-dependent nucleosome assembly | biological process | HIST1H4A, NASP, IPO4, RBBP4, HAT1, H3C1, CHAF1A, ASF1B, H4-16 |
| DNA replication-independent nucleosome assembly | biological process | HIST1H4A, NASP, ATRX, IPO4, HIRA, RBBP4, HAT1, UBN1, CABIN1, H3-3A, ASF1B, H4-16 |
| DNA replication-independent nucleosome organization | biological process | SUPT16H |
| DNA rewinding | biological process | SMARCAL1, ZRANB3 |
| DNA strand elongation | biological process | TERT |
| DNA strand elongation involved in DNA replication | biological process | PCNA, MCM3, RFC4, GINS1, GINS3, RFC3, POLD2, MCM4, MCM7, GINS2, POLA1 |
| DNA strand elongation involved in mitotic DNA replication | biological process | GINS1 |
| DNA strand renaturation | biological process | TP53, RECQL, SMARCAL1, SMARCA1, ZRANB3, BLM, RECQL4, RAD54L |
| DNA strand resection involved in replication fork processing | biological process | MRE11, SAMHD1 |
| DNA synthesis involved in DNA repair | biological process | BRCA1, BRCA2, ATM, NBN, POLH, RFC3, CDKN2D, WRNIP1, HROB, POLE, POLD4, POLD1, POLA1 |
| DNA synthesis involved in UV-damage excision repair | biological process | TREX1, POLA1 |
| DNA topological change | biological process | TOP2A, TOP1, HMGB1, TOP2B, TOP3B, TOP1MT |
| DNA unwinding involved in DNA replication | biological process | TOP2A, SSBP1, PURA, RECQL5, RPA1, RECQL, BLM, MCM4, MCM7, MCM6, RECQL4, MCM2 |
| DNA-dependent DNA replication | biological process | POLQ, POLG, REV3L, RFC4, RFC5, RFC3, BAZ1A, RPA1, POLG2, CDK2AP1, WRNIP1, RFC2, MCMBP, POLD4, WDHD1, POLB, HELB, POLD1, POLN, RFC1 |
| DNA-templated transcription, elongation | biological process | ELL3, TCEA2 |
| DNA-templated transcription, initiation | biological process | TAF4B, TBPL1, HIST1H4A, TAF5, TAF12, TBPL2, NAT14, SMARCA5, NCOA6, RSF1, TAF9B, GTF2B, POLR2D, TAF13, TAF7, TAF6L, TAF1, RRN3, TAF6, TAF4, TAF10, BRF2, BRF1, CRCP, TAF9, H4-16 |
| DNA-templated transcription, termination | biological process | MTERF1, TTF2, TTF1, SETX, XRN2, SMN1, POLR2A, CAVIN1 |
| dolichol biosynthetic process | biological process | SRD5A3, NUS1 |
| dolichol metabolic process | biological process | SRD5A3, DPAGT1, DPM2, DPM1 |
| dolichol-linked oligosaccharide biosynthetic process | biological process | ALG2, ALG14, SRD5A3, ALG8, ALG10, DPAGT1, ALG10B, ALG13, ALG1, ALG3, MPDU1 |
| dolichyl diphosphate biosynthetic process | biological process | SRD5A3, DPAGT1, NUS1, MVD, DOLK |
| dolichyl monophosphate biosynthetic process | biological process | DOLK |
| dopamine biosynthetic process | biological process | DAO, SNCA, DDC, NR4A2, TGFB2, GCH1, TH, SLC6A3 |
| dopamine biosynthetic process from tyrosine | biological process | TH |
| dopamine catabolic process | biological process | COMT, MOXD1, SULT1A3, DBH, SLC6A3 |
| dopamine metabolic process | biological process | COMT, SNCAIP, PRKN, NR4A2, HPRT1, ATP7A, LRTOMT, NPR1, DRD3, DRD1, GRIN2A, DRD2, DRD4 |
| dopamine receptor signaling pathway | biological process | GSK3B, GNAO1, GNB5, GNAI3, KLF16, ADCY6, NSG2, DRD3, SULT1A3, DRD1, CALY, NSG1, DRD2, ARRB2, RGS9, DRD4 |
| dopamine transport | biological process | DRD1, CHRM5, SLC18A2, SLC6A3, SLC22A1, SLC22A3 |
| dopamine uptake | biological process | SLC22A2, MAPK15, SLC6A3, SLC22A1, SLC22A3 |
| dopamine uptake involved in synaptic transmission | biological process | PARK7, SLC6A2, SNCA, PRKN, SLC6A3 |
| dopaminergic neuron axon guidance | biological process | FZD3, VANGL2, CELSR3 |
| dopaminergic neuron differentiation | biological process | VEGFA, HIF1A, CTNNB1, FGF8, SHH, PHOX2B, MANF, FOXA1, LMX1B, LRP6, NR4A2, RSPO2, CDNF, PHOX2A, PITX3, EN1, LMX1A, FOXA2 |
| dorsal aorta development | biological process | NKX3-1, NGFR |
| dorsal aorta morphogenesis | biological process | BMPR1A, RBPJ, HEY2, SRF, HEY1, ENG, ACVRL1 |
| dorsal root ganglion development | biological process | CTNNB1, UNC5C, POU4F2, RGS4 |
| dorsal root ganglion morphogenesis | biological process | NRP2, NRP1 |
| dorsal spinal cord development | biological process | PBX3, DRAXIN, DAAM2, HOXB8, PROX1 |
| dorsal spinal cord interneuron posterior axon guidance | biological process | LHX1 |
| dorsal/ventral axis specification | biological process | CTNNB1, SENP2, BMPR1A, VAX2, MDFI, WNT3 |
| dorsal/ventral axon guidance | biological process | FGF8, SLIT1, DCC |
| dorsal/ventral neural tube patterning | biological process | BMP4, SHH, PAX7, TULP3, TCTN1, FOXA1, WNT3A, PSEN1, SMO, GSC, FKBP8, GLI2, PTCH1 |
| dorsal/ventral pattern formation | biological process | CTNNB1, PROP1, SHH, DUSP6, DYNC2H1, DSCAML1, GLI3, OVOL2, IFT52, HOXA2, LHX3, BMPR1A, LMX1B, HOXD11, ARL13B, SP8, AIDA, LHX1, SMO, FOXG1, TBX20, GLI1, EN1, CHRD, IFT122, FKBP8, EDN1, HOXA11, HHIP, HOXB2, LRP4, GLI2, PTCH1, WNT7A, IFT172, LHX2 |
| dosage compensation | biological process | MACROH2A2, MACROH2A1 |
| dosage compensation by inactivation of X chromosome | biological process | BRCA1, EXOSC10, HNRNPU, YTHDC1, RBM15, EIF1, UPF1, SMCHD1, LRIF1, RBM15B |
| double-strand break repair | biological process | BRCA1, LIG4, BRCA2, ERCC1, CIB1, POLQ, PARP1, H2AFX, RNF8, NBN, MSH2, DDX1, UIMC1, XRCC5, FEN1, RNF168, DTX3L, APTX, SETX, TRIP13, DCLRE1C, BABAM1, BABAM2, ABRAXAS1, TDP1, PARP3, RAD52, MRE11, RAD21, NIPBL, KAT5, MEIOC, PRKDC, TDP2, XRCC4, SMCHD1, MAD2L2, RAD50, EXD2, LIG3, TENT4A, EYA1, BRIP1, MARF1, CDCA5, APLF, INO80, APBB1, EME2, RAD54L, ACTR5, TP53, TNKS1BP1, NHEJ1 |
| double-strand break repair involved in meiotic recombination | biological process | FANCD2, BRIP1, MCMDC2 |
| double-strand break repair via alternative nonhomologous end joining | biological process | POLQ, HMCES, PRKDC, LIG3 |
| double-strand break repair via break-induced replication | biological process | CDC7, MCM3, MUS81, CDC45, MCM5, MCM4, MCM7, MCM6, GINS2, MCM2 |
| double-strand break repair via classical nonhomologous end joining | biological process | LIG4, ERCC6, ERCC8, XRCC6, UVRAG, ZBTB7A |
| double-strand break repair via homologous recombination | biological process | BRCA1, BRCA2, XRCC1, ATM, POLQ, PARP1, REC8, H2AFX, NBN, XRCC2, MEIOB, KASH5, HELQ, RBBP8, MCM8, FAN1, REV3L, NSMCE2, MORF4L1, RPA2, FEN1, SWSAP1, SLX1A, PSMD14, AP5Z1, RAD51C, SFPQ, UBE2N, AP5S1, RECQL5, SMC5, MCM9, RPA1, SLX4, RNF138, RECQL, KDM4D, RFWD3, RAD52, MRE11, YY1, SWI5, NABP1, SAMHD1, HUS1, RPA3, GEN1, SFR1, FBH1, WDR48, NSMCE1, PALB2, RAD50, ERCC4, EXD2, RAD51B, RAD51D, BLM, MMS22L, HUS1B, ZFYVE26, STN1, LIG3, RECQL4, RAD51AP1, NABP2, AUNIP, POLL, INO80, TONSL, XRCC3, SPIDR, POLN, RAD54B, RAD54L, RMI1 |
| double-strand break repair via nonhomologous end joining | biological process | BRCA1, LIG4, ATM, MLH1, H2AFX, SUMO1, RNF8, NBN, HIST1H4A, NSMCE2, UIMC1, XRCC5, RNF168, PRPF19, ATP23, PSMD14, UBE2N, SMC5, DCLRE1C, BABAM1, BABAM2, XRCC6, ABRAXAS1, DCLRE1B, MRE11, SMARCAL1, NSD2, KAT5, PRKDC, XRCC4, KDM2A, UBE2V2, CYREN, TP53BP1, RIF1, RAD50, ERCC4, BARD1, DCLRE1A, POLB, POLL, PIAS4, PAXX, HERC2, PAXIP1, DNTT, MDC1, POLA1, H4-16, NHEJ1 |
| double-strand break repair via single-strand annealing | biological process | RAD52 |
| double-strand break repair via synthesis-dependent strand annealing | biological process | XRCC3, RAD54L |
| doxorubicin metabolic process | biological process | AKR1C3, AKR1B1, AKR7A2, AKR1A1, AKR1C2, CBR4, AKR1B10, AKR1C1, AKR1C4 |
| doxorubicin transport | biological process | RALBP1 |
| drinking behavior | biological process | OXT, UCN, EN1, HTR1B, DRD2, MMP17 |
| drug catabolic process | biological process | CYP1A2, CYP3A5, FMO4, CYP2D6, CYP2C9 |
| drug export | biological process | NR1I2, SLC22A18 |
| drug metabolic process | biological process | CYP1A1, CYP1A2, CYP2B6, EPHX2, UGT1A8, ADH1A, UGT1A4, CYP2C8, CYP2A6, CBR1, CYP2C19, TPMT, ADAL, CYP4F12, AOX1, CYP2E1, CYP4F2, NT5C2, CYP2D6, CAD, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10, FMO1, VKORC1, CYP2C9 |
| drug transmembrane transport | biological process | ABCB1, SLC22A18, SLC22A5, SLC22A2, TMEM30A, ATP8B1, ABCB11, SLC22A1, SLC22A3 |
| drug transport | biological process | SLC22A18, SLC22A5 |
| dsRNA transport | biological process | RFTN2, FLOT1, RFTN1 |
| dTDP biosynthetic process | biological process | DTYMK |
| dTMP biosynthetic process | biological process | TYMS, SHMT1, CDADC1, DCTD |
| dTTP biosynthetic process | biological process | TBPL1, TYMS, DTYMK |
| ductus arteriosus closure | biological process | HPGD, MYOCD, FOXF1, STRA6 |
| dUDP biosynthetic process | biological process | DTYMK |
| dUMP biosynthetic process | biological process | CDADC1, DUT, DCTD |
| dUMP catabolic process | biological process | NT5M |
| dUMP metabolic process | biological process | TYMS |
| dUTP catabolic process | biological process | DUT |
| dynamin family protein polymerization involved in mitochondrial fission | biological process | DNM1L, MIEF2 |
| ear development | biological process | BCL2, DDR1, BCL2L11, PRKRA, ECE1, GATA3, BMP5, DLX5, GSC, RDH10, TCF15, SHROOM2, STRA6 |
| ear morphogenesis | biological process | CHD7, WDR19, NIPBL, EYA1, GJB6 |
| early endosome to late endosome transport | biological process | LMTK2, SNX16, AKTIP, STX8, ANKRD27, PTPN23, RAB5A, HOOK3, PIK3C3, WDR91, EMP2, HOOK2, KIF16B, WDR81, RAB7A, BECN1, EEA1, SNF8, RILP, FAM160A2 |
| early endosome to recycling endosome transport | biological process | CORO1A, MYO1D |
| early viral transcription | biological process | MON1B |
| eating behavior | biological process | TRH, STAT3, LEP, OXTR, OXT, IAPP, CPT1A, BBS12, NMU, ATP8A2, OPRD1, P2RY1, TH, HCRT, CCK, TCF15, OPRL1, PRLH, ADORA2A, UCHL1, NPY5R |
| ectoderm and mesoderm interaction | biological process | TP63 |
| ectoderm development | biological process | CTNNB1, SHH, NF2, BMPR1A, KRT6B, EPB41L5, AMER2, VAX2, ZBTB17, ZBTB7B, GRHL3 |
| ectoderm formation | biological process | LHX1 |
| ectodermal cell differentiation | biological process | ITGA6, VPS52, ITGAM, EDA2R |
| ectodermal cell fate commitment | biological process | ETS2 |
| ectopic germ cell programmed cell death | biological process | IL1B, KITLG, BAX, IL1A, KIT, CASP2, PRKDC |
| efferent axon development in a lateral line nerve | biological process | PHOX2B |
| egg activation | biological process | PLCZ1 |
| egg coat formation | biological process | POMZP3, ZP3 |
| eiF2alpha phosphorylation in response to endoplasmic reticulum stress | biological process | EIF2AK3 |
| elastic fiber assembly | biological process | TNXB, MFAP4, MYH11, FBLN5, LOX, THSD4, ATP7A, EMILIN1, EFEMP2 |
| elastin biosynthetic process | biological process | ATP7A |
| elastin metabolic process | biological process | HIF1A |
| electron transport chain | biological process | SDHA, AKR1B1, HAAO, GLRX5, ADH5, GLDC, CYB5B, ETFDH, TXNRD1, AOC2, DHRS3, CIAPIN1, COX7B2, NMES1, NDUFS4, AKR7A2, CYBB, COX7A2, COX11, AKR1A1, SH3BGRL3, LOXL2, IDO1, ME1, GLRX2, POR, WDR93, STEAP4, GLRX3, FDX1, CYBA, CYB561, PTGES2, HSD17B6, DEGS1, IDH3B, NCF1, ALDH2, MT-CO2, DMGDH, QDPR, GPX2, SURF1, PHGDH, ASPH, TSTA3, FDX2, AOX1, NDUFA4L2, ME2, ALDH4A1, GLRX, COX8C, P4HA2, NQO2, COX7A1, AKR1C4, DHDH |
| electron transport coupled proton transport | biological process | MT-ND5, NDUFS7 |
| embryo development | biological process | NR5A2, BAG6, NRG1, SHH |
| embryo development ending in birth or egg hatching | biological process | CYP1A1, FGF8, FXN, TDGF1, STOX2, SCEL, USP22, MFRP, UBR3, CELF4, TGFB2, CDK5R1, HUS1, FOXI1, AKIRIN2, ANKS6, SEBOX, CAMSAP3, OSR2, TP53, EVX1 |
| embryo implantation | biological process | SOD1, IL1B, MMP2, MMP9, LIF, PTGS2, FKBP4, PRLR, PLAU, DDR1, POLR1B, RPL29, TPPP3, PPARD, SPP1, TRO, UBE2Q1, EMP2, FBLN1, IGFBP7, STC2, PTGIS, ARID1A, CALCA, TGFBR2, FUT7, EPO, RECK, H3-3A, VMP1, Grn |
| embryonic axis specification | biological process | CTNNB1, COBL, CITED1, FZD5, STIL, WNT7A |
| embryonic body morphogenesis | biological process | ZNF281, CDON, GREM2, MAB21L2, IFT122, FUZ |
| embryonic brain development | biological process | CTNNB1, TRA2B, TBC1D23, RPL10, MFSD2A, EN1, MED12, EN2, CC2D2A |
| embryonic camera-type eye development | biological process | ALDH1A2, WDR19, TRAF3IP1, TULP3, ALDH1A3, FZD5, RDH10, RARG, NES, FGF10, RARA, PPP1R13L |
| embryonic camera-type eye formation | biological process | TWIST1, STRA6 |
| embryonic camera-type eye morphogenesis | biological process | BMP7, HIPK1, SP3, LRP6, HIPK2, ZEB1, IFT122, TH, FOXF2, FZD5, IHH, IFT172, TBX2 |
| embryonic cleavage | biological process | ERCC2, TOP2A, TOP1, TPRA1 |
| embryonic cranial skeleton morphogenesis | biological process | GNAS, FGFR2, NODAL, CTNNB1, BMP4, WDR19, WNT9B, PRRX1, TFAP2A, MMP16, PAX5, NIPBL, MMP14, TWIST1, FOXC2, TGFBR1, IRX5, SMAD2, SIX1, SIX2, RUNX2, SIX4, ALX3, TGFBR2, SLC39A3, PDGFRA, SLC39A1, EIF4A3, SMAD3, DLX2, TBX15 |
| embryonic digestive tract development | biological process | TNF, CXCL8, ALDH1A2, FGF9, GLI3, RARB, TGFB2, ADA, FOXF2, SCT, FOXF1, SALL1, RARRES2, GLI2, PKDCC, STRA6, FGF10 |
| embryonic digestive tract morphogenesis | biological process | FGFR2, HNF1B, SHH, GLI3, TCF7, OVOL2, SOX11, NIPBL, SIX2, ID2, FOXF1, HLX, PDGFRA, IHH, RBPMS2, FGF10 |
| embryonic digit morphogenesis | biological process | CTNNB1, BMP4, GJA1, SHH, MYCN, GLI3, HOXD13, TRAF3IP1, LMBR1, IFT52, TULP3, SMAD4, HDAC2, FLVCR1, ECE1, CPLANE1, MAP3K20, BPNT2, INTU, B9D1, BMPR1A, CREBBP, MSX1, FREM2, TMEM107, GNA12, C2CD3, TWIST1, TBC1D32, TBX3, ALX4, LRP5, SFRP2, IFT122, HOXC11, MSX2, SALL1, HOXA11, ZBTB16, LRP4, GLI2, ROR2, IHH, WNT7A, CHST11, OSR2, LNPK, HAND2, TBX2 |
| embryonic ectodermal digestive tract development | biological process | VPS52 |
| embryonic ectodermal digestive tract morphogenesis | biological process | FOXF1 |
| embryonic epithelial tube formation | biological process | WNT4, RET |
| embryonic eye morphogenesis | biological process | RARB, FBN2, FBN1, MFAP2, MFAP5, ALDH1A3, VAX2, RARG, FOXL2, EFEMP1 |
| embryonic foregut morphogenesis | biological process | CTNNB1, GATA4, SHH, ACVR2B, EPB41L5, SMAD2, FOXF1, SMAD3 |
| embryonic forelimb morphogenesis | biological process | CTNNB1, SHH, ALDH1A2, CACNA1C, MSX1, RSPO2, TFAP2A, NIPBL, TBX5, TWIST1, TBX3, ALX4, EN1, RUNX2, IFT122, ALX3, MSX2, RDH10, HOXA11, HOXA9, WNT9A, CRABP2, WNT3, WNT7A, RECK, RPGRIP1L, OSR2, LNPK |
| embryonic genitalia morphogenesis | biological process | TCF7, ROR2, FGF10 |
| embryonic heart tube anterior/posterior pattern specification | biological process | GATA4, BMP2, FOXH1 |
| embryonic heart tube development | biological process | NODAL, CTNNB1, GJA1, FGF8, TRAF3IP1, SOX18, NDRG4, FOXC2, TBX3, TBX20, GJA5, IFT122, FOXC1, NKX2-5, TBX2 |
| embryonic heart tube elongation | biological process | TBX20 |
| embryonic heart tube left/right pattern formation | biological process | MEGF8, CITED2, IFT122, NKX2-5 |
| embryonic heart tube morphogenesis | biological process | ACVR1, HES1, RYR2, MEGF8, TEAD2, YAP1, TBX20, MESP1 |
| embryonic hemopoiesis | biological process | KITLG, HIF1A, KDR, KIT, SH2B3, TPO, GATA3, IL3, ATF4, PBX1, KMT2A, TGFBR2, ZFPM1, CCDC134, FLT3LG, GATA1 |
| embryonic hindgut morphogenesis | biological process | HOXD13, TCF7, DACT1 |
| embryonic hindlimb morphogenesis | biological process | GNAS, CTNNB1, BMP4, FGF8, SHH, CHD7, RARB, NOTCH1, MSX1, RSPO2, TWIST1, TBX3, ALX4, ALX3, MSX2, AFF3, ZBTB16, RARG, GPC3, WNT3, WNT7A, RPGRIP1L, OSR2 |
| embryonic limb morphogenesis | biological process | FGFR1, BMP7, BMP4, SHH, CYP26B1, ALDH1A2, FGF9, DYNC2H1, TP63, GLI3, HOXD13, WDR19, PBX2, FBN2, NOTCH1, MBNL1, SKI, MSX1, DKK1, SP8, LRP6, PSEN1, PRRX1, MEGF8, SALL4, FRAS1, PBX1, TGFB2, C2CD3, TBX5, HOXC10, TWIST1, DLX6, HOXD10, LEF1, GJA5, DLX5, EN1, MSX2, HOXA11, LRP4, MYH3, PTCH1, WNT7A, CHST11, GREM1, HOXA10, GDF5, ALX1 |
| embryonic liver development | biological process | GAMT, CCDC134 |
| embryonic lung development | biological process | PDGFA |
| embryonic morphogenesis | biological process | ZEB2, FLT1, HNF1B, BMP4, SHH, FLRT3, GLI3, ROCK2, BMPR1A, YBX1, MSX1, ROCK1, TMED2, CDON, ZEB1, YTHDF2, MSX2, C2orf49, FGF2, HTR2B |
| embryonic nail plate morphogenesis | biological process | MSX1, MSX2, FZD6 |
| embryonic neurocranium morphogenesis | biological process | TGFB3, MTHFD1, GLI3, TULP3, MTHFD1L, NDST1, MED12 |
| embryonic olfactory bulb interneuron precursor migration | biological process | ARX |
| embryonic organ development | biological process | ERCC1, FGFR2, RAD23B, SHH, GLI3, ARID2, ZFPM2, PBX2, RBBP6, BMPR1A, PBX3, WNT7B, SYF2, GATA3, SMO, PBX1, TEAD2, TEAD1, WDR48, ZFP36L1, PALB2, EPN1, MBD3, MED12, PBX4, PDGFRB, POLE, RDH10, TEAD4, PDGFC, PTCH1, TEAD3, TP53 |
| embryonic organ morphogenesis | biological process | FGFR2, NEUROD1, FOXE1, RBP4, HOXC4 |
| embryonic pattern specification | biological process | FGFR2, NODAL, BMP7, SHH, PGAP1, LRP6, LHX1, MEIS3, OOEP, SMAD2, RIPPLY3, MEIS1, EFNB1, MEIS2, ZBTB16, IHH, SIM2, SMAD3, SATB2, SMAD5, FGF10 |
| embryonic placenta development | biological process | EGFR, HIF1A, HSF1, NODAL, PKD1, PDGFB, SPINT1, SP3, PRDM1, PKD2, TMED2, TTPA, BPTF, GATA2, EPAS1, TFEB, ESRRB |
| embryonic placenta morphogenesis | biological process | ZNF568, WNT7B |
| embryonic process involved in female pregnancy | biological process | HSF1, NODAL, SP3, ACSL4, JUNB, TLE6 |
| embryonic retina morphogenesis in camera-type eye | biological process | HIPK1, LRP6, LHX1, CDON, HIPK2, RBP4, PROX1 |
| embryonic skeletal joint development | biological process | EXT1, SLC2A10, IHH, WNT9A, OSR2 |
| embryonic skeletal joint morphogenesis | biological process | BMP7, BMP4, COL2A1, HOXC11, HOXA11, OSR2 |
| embryonic skeletal limb joint morphogenesis | biological process | CTNNB1, OSR2 |
| embryonic skeletal system development | biological process | DMRT2, BMP4, SHH, FGF9, HOXA3, PAX7, HOXA6, MBTD1, SLC35D1, HOXA5, PCGF2, HSD17B7, HOXB5, NKX3-2, HOXB9, SP3, DEAF1, KIAA1217, XYLT1, HOXD1, HOXC9, PBX1, TAPT1, HOXB6, HOXC6, ACVR2A, HOXC5, WNT11, SULF1, RBP4, HOXA9, DLX1, SULF2, DLX2 |
| embryonic skeletal system morphogenesis | biological process | BMP4, DSCAML1, MYCN, HOXA3, GLI3, COL11A1, HOXA6, HOXA2, HOXD3, FLVCR1, HOXA5, PCGF2, HOXB5, HOXB9, MEF2C, HOXC9, PRRX1, MEGF8, SOX11, DLG1, HOXB7, TWIST1, HOXB6, HOXA7, ZEB1, WDR60, FOXC2, HOXD10, HOXB4, SIX1, ALX4, SIX2, GSC, SIX4, ALX3, EYA1, HOXB3, PDGFRA, HOXB8, FUZ, HOXC4, HOXB2, HOXA9, MDFI, WNT9A, CHST11, SATB2, OSR2, HOXA4, ALX1, TBX15 |
| embryonic viscerocranium morphogenesis | biological process | MTHFD1, HOXA2, MTHFD1L, MEF2C, LHX1, NDST1, NIPBL, FOXC2, RDH10, CHST11 |
| enamel mineralization | biological process | FOXO1, CNNM4, FAM20C, FAM20A, NECTIN1, MSX2, TCIRG1, PPARA, WDR72, STIM1 |
| endocannabinoid signaling pathway | biological process | DAGLB, ALOX15B, DAGLA |
| endocardial cell differentiation | biological process | NRG1, SMAD4, SOX18, NOTCH1 |
| endocardial cushion cell development | biological process | JAG1 |
| endocardial cushion cell fate commitment | biological process | ACVR1 |
| endocardial cushion development | biological process | BMP4, GATA4, CRELD1, NOTCH1, NEDD4, TBX5, TMEM100, RBM24, ERBB3, FOXF1 |
| endocardial cushion formation | biological process | BMPR1A, ROBO2, BMP5, TBX20, ROBO1 |
| endocardial cushion fusion | biological process | GATA5, ACVR1, TGFB2, TGFBR2 |
| endocardial cushion morphogenesis | biological process | SOX9, MDM2, ISL1, ACVR1, BMPR1A, MDM4, NOTCH1, TGFB2, TWIST1, TBX20, BMP2, HEY1, ENG, ACVRL1, TBX2 |
| endocardial cushion to mesenchymal transition | biological process | HAS2, ENG, ACVRL1 |
| endocardial cushion to mesenchymal transition involved in heart valve formation | biological process | EFNA1, HEY2 |
| endocardium development | biological process | STK3, STK4, NOTCH1, RBPJ |
| endocardium formation | biological process | OVOL2, SOX18, PROX1 |
| endocardium morphogenesis | biological process | NOTCH1, RBPJ |
| endochondral bone growth | biological process | FGFR3, MSX2, OSTN, COMP, EVC |
| endochondral bone morphogenesis | biological process | SOX9, BMPR2, CARM1 |
| endochondral ossification | biological process | GNAS, FGFR3, BMP4, PEX7, CSGALNACT1, BPNT2, COL2A1, TEK, MEF2C, NAB1, SMPD3, MMP16, PHOSPHO1, MMP14, IFT80, MEF2D, BMP6, FGF18, MMP13, DLX5, RUNX2, FOXC1, NAB2, ALPL, COL13A1 |
| endocrine pancreas development | biological process | IL6, IL6R, SOX9, BAK1, AKT1, HNF1B, CLU, FOXO1, NKX2-2, RFX3, ANXA1, GIPR, PDX1, ONECUT2, NEUROD1, INSM1, SOX4, RFX6, MNX1, ONECUT1, EIF2AK3, FOXA2 |
| endocrine signaling | biological process | KRAS |
| endocrine system development | biological process | INSM1 |
| endocytic iron import into cell | biological process | TFR2 |
| endocytic recycling | biological process | LMTK2, SNX3, ACAP2, VPS29, CCDC93, VPS52, KIAA1109, DENND1C, SNX4, RAB11FIP4, PTPN23, DENND1A, VPS26C, EPS15, RAB35, EHD4, GGA3, RAB14, CMTM6, DENND1B, VPS35L, VPS53, SNF8, VPS50, SNX12, ARL4C, VPS51, CCDC22, ARF6, EHD2, EHD3, RAB17, EIPR1, RAB11FIP3, SNX17, MICALL2, MICALL1 |
| endocytosis | biological process | NOSTRIN, APP, CDC42, SHH, DNM1L, WIPF3, SYNJ1, PSTPIP1, MARCHF3, RIN2, ACKR4, MRC2, RABEP1, DPYSL2, MIB1, EHBP1, SH3BP4, AP3M1, PIK3C2A, AP2S1, OLR1, FNBP1, MTMR6, SNX2, RAB1A, ENPP2, RHOU, ILDR1, C9orf72, EPN3, LY75, RALBP1, DENND1C, ENTHD1, REPS1, SH3GL2, SYNRG, SNX10, FCHO1, WIPF1, FCHSD2, FNBP1L, RUFY1, LOXL2, TFRC, AP3M2, DAB2, DENND1A, SH3GL3, LDLR, RAB5A, EPS15, CTTN, RINL, TOM1, AP2A2, ASGR2, VLDLR, PICALM, SRL, PIK3C3, ANKFY1, RABGEF1, RAB22A, DNM3, SNAP91, SYP, MRC1, UNC119, CLINT1, SNX33, HOOK2, CD209, MARCO, DMBT1, SNX5, ENPP1, CAV3, RIN1, SSC4D, AP2M1, EHD4, DBNL, PACSIN2, TMPRSS2, LRP6, AMPH, PRSS12, ARHGAP27, USP33, MYO6, SNX9, ATP9B, RAB7A, TMPRSS15, PLA2R1, DENND1B, MTMR9, ATP9A, RHOQ, LRP2, ANK2, AAK1, STEAP2, CLTA, GHR, AP2B1, BECN1, EQTN, WASF2, ESYT2, ABL1, FCHO2, EEA1, HHIPL1, HEATR5B, TMPRSS3, MIA3, RABGAP1L, RUBCN, SORT1, ATP6V1H, LRP12, STON1, NPC1, GAPVD1, SORL1, ITSN2, EPN1, PIK3CG, TRIP10, LMBR1L, MARCHF2, OPHN1, LRP5, VTN, RAB5B, BCL2L1, LRP1, CLEC10A, NECAP1, REPS2, SCARF2, CYTH2 |
| endocytosis involved in viral entry into host cell | biological process | env |
| endoderm development | biological process | TGFB1, HNF1B, NODAL, GATA4, LAMC1, EXT1, SMAD4, EOMES, BMPR1A, PELO, NOTCH1, KIF16B, DKK1, MIXL1, LHX1, EPB41L5, BPTF, SMAD2, MED12, HOXC11, GDF3, ONECUT1, SMAD3, NKX2-1 |
| endoderm formation | biological process | CTNNB1, EOMES, DKK1, MIXL1, LHX1, DUSP5, SMAD2, DUSP1, TBX20, SOX7, DUSP2 |
| endodermal cell differentiation | biological process | MMP2, INHBA, MMP9, NODAL, ITGA5, ITGAV, ITGA4, FN1, COL11A1, ITGB5, COL12A1, COL8A1, COL7A1, MMP15, COL4A2, HMGA2, MIXL1, HSBP1, COL6A1, MMP14, VTN, ITGB2, LAMB1, LAMB3, ITGA7, LAMA3, MMP8 |
| endodermal cell fate commitment | biological process | CTNNB1, PAF1, RTF1, CTR9, CDC73, LEO1 |
| endodermal cell fate specification | biological process | HNF1B, SOX2, EOMES |
| endodermal digestive tract morphogenesis | biological process | ID2 |
| endomembrane system organization | biological process | ARFGEF1, ARFGEF2 |
| endomitotic cell cycle | biological process | CIB1, UBA3, PLK3 |
| endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | NOP14, UTP23, FCF1, UTP20, RCL1, TBL3 |
| endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | RPS21, NOP14, FCF1, UTP20, RRS1, KRI1, RCL1 |
| endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | TSR1, RCL1, BMS1 |
| endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | RPS21 |
| endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | NOP14, UTP20, TBL3 |
| endoplasmic reticulum calcium ion homeostasis | biological process | BCL2, BAX, BAK1, WFS1, ATP2A2, CAMK2D, TMBIM6, HERPUD1, PSEN1, PML, CCDC47, ITPR1, KCTD17, PACS2 |
| endoplasmic reticulum localization | biological process | MYO5A |
| endoplasmic reticulum mannose trimming | biological process | MAN1B1, DERL2, TRIM13, RNF103, SEL1L, RNF139, RNF185, OS9, SYVN1, UGGT1, MARCHF6, AMFR, UGGT2 |
| endoplasmic reticulum membrane fusion | biological process | BNIP1 |
| endoplasmic reticulum membrane organization | biological process | VAPB, TRDN, STX18, MOSPD3, LPCAT3 |
| endoplasmic reticulum organization | biological process | RTN4, SEC31A, LMAN2L, SEC16A, VAPB, BNIP1, ATL1, LMAN1, LMAN2, TMEM38B, CAV2, VAPA, TMCC1, CERT1, ATL3, TOR1AIP2, MIA3, CCDC47, GAK, TOR1B, SMPD4, SEC61A1, SEC31B, ATL2, MAPK15, CASQ1, DOP1B, LMAN1L, LRRK2, SEC16B, LNPK, EIF2AK3 |
| endoplasmic reticulum polarization | biological process | SHTN1 |
| endoplasmic reticulum tubular network formation | biological process | ARL6IP1, RTN4, RTN3 |
| endoplasmic reticulum tubular network maintenance | biological process | LNPK |
| endoplasmic reticulum tubular network membrane organization | biological process | ARL6IP1, RTN4, ATL1, ATL2 |
| endoplasmic reticulum tubular network organization | biological process | REEP5, RAB18, RTN4, REEP1, RTN3, REEP4, REEP6, TMEM170A, TMEM33, REEP3, LNPK |
| endoplasmic reticulum unfolded protein response | biological process | IFNG, ATF3, NFE2L2, HSPA5, WFS1, SELENOS, DERL2, CANX, DDIT3, SERP1, CREBRF, DERL1, VAPB, XBP1, CREB3, MBTPS1, CDK5RAP3, STUB1, CCND1, HERPUD1, CREB3L2, ERO1A, ATF4, RNF175, PARP16, STC2, ERN1, MBTPS2, YOD1, RHBDD2, CTH, PARP6, PTPN1, BHLHA15, TBL2, CREB3L3, SYVN1, EIF2AK2, RNF121, PARP8, HERPUD2, ATF6B, FGF21, ERN2, CALR, DERL3, AMFR, SERP2, EIF2AK3 |
| endoplasmic reticulum-Golgi intermediate compartment organization | biological process | STX17, GBF1 |
| endoplasmic reticulum-plasma membrane tethering | biological process | VAPB, MOSPD3, ESYT2, GRAMD2A, ESYT1, ESYT3 |
| endosomal lumen acidification | biological process | FASLG, AQP11, CLCN3 |
| endosomal transport | biological process | BLOC1S2, DPY30, AP5M1, CHMP2A, TSG101, ARL8B, ALS2, CHMP5, VPS28, AP5Z1, WASHC5, SNX27, VTA1, VPS4B, RPS27A, KIAA1109, REPS1, CHMP4A, AP5S1, CORO1C, VPS36, WASHC4, HGS, EPS15, ZFYVE16, STAM, CHMP4B, UBAP1, TOM1, PICALM, RAB35, SRL, ANKFY1, BLOC1S1, SNX33, CHMP6, EHD4, SQSTM1, SNX9, STAM2, TMCC1, VPS37C, ARHGAP1, ALMS1, NSG2, UBC, SNF8, AGAP2, MYO5B, DCLK1, UBA52, VPS37A, VPS37B, ITSN2, LAMTOR1, TINAGL1, REPS2, CHMP4C, MVB12A, VPS25, EHD2, CHMP7, VPS16, WAS, SNX18, CALY, EHD3, UBB, NSG1, CLEC16A, SNX17, ITSN1, MVB12B, EPS15L1, CHMP3, RASSF9, ZFYVE9, ANXA8 |
| endosomal vesicle fusion | biological process | VPS41, ANKFY1, TGFBRAP1, VPS8, SAMD9, VPS39 |
| endosome fission | biological process | CORO1C, TMCC1 |
| endosome membrane tubulation | biological process | CORO1C, TMCC1 |
| endosome organization | biological process | USP8, PHETA2, RNF26, ALS2, VPS18, LAPTM4B, AKTIP, VPS4B, SNX10, PHETA1, ARFGEF2, WASHC4, PI4K2B, VPS33B, HOOK3, PIK3C3, RAB22A, SNX33, HOOK2, TMEM127, SQSTM1, EXOC8, PI4K2A, LAMTOR1, RAB5B, FAM160A2, PLEKHJ1, DNM1, ALS2CL, PLEKHF1, ANXA8 |
| endosome to lysosome transport | biological process | VPS41, TRAK2, SNX16, MTM1, TSG101, CHMP5, VPS18, DTX3L, SNX27, AKTIP, STX8, SNAPIN, VPS33B, M6PR, HOOK3, VIPAS39, ADRB2, GPRASP1, HOOK2, MGRN1, TRAK1, RAB7A, VAMP7, SCYL2, SORT1, HMGXB4, RILP, FAM160A2, TGFBRAP1, CDX2, VPS16, VPS33A, DENND3, CLEC16A, BIN1, PCDHGA3, VPS39, KIF13A |
| endosome to lysosome transport via multivesicular body sorting pathway | biological process | LYST, VPS4B, UBXN6, MVB12A |
| endosome to melanosome transport | biological process | RAB38, ANKRD27, AP1G1, AP3D1, RAB32, CD63, BLOC1S6, AP1M1 |
| endosome to plasma membrane protein transport | biological process | TRARG1 |
| endosome transport via multivesicular body sorting pathway | biological process | CHMP2A, VPS28, LAPTM4B, VPS36, CHMP1A, VPS37C, SORT1, VPS37A, VPS37B, DENND10, RILP, CHMP3, CHMP1B |
| endothelial cell activation | biological process | SMAD4, FOXP1, APOLD1, TGFBR1, BMPER, P2RX4, HOXA9, CXCL10 |
| endothelial cell apoptotic process | biological process | BMPR2, DAB2IP, HIPK1, COL4A3, MAP3K5, FGF21, TNF |
| endothelial cell chemotaxis | biological process | VEGFA, CORO1B, EGR3, CCN3, NRP1, PLEKHG5, NR4A1 |
| endothelial cell chemotaxis to vascular endothelial growth factor | biological process | GAB1 |
| endothelial cell development | biological process | GPX1, VEZF1, CCM2 |
| endothelial cell differentiation | biological process | CXCR4, KDM6B, PTN, HOXB5, EDF1, S1PR1, NOTCH4, SCUBE1, MESP1, PROX1, JAG1 |
| endothelial cell migration | biological process | NOS3, STAT1, PTEN, PIK3CA, CYP1B1, PXN, ADGRA2, GIPC1, TNFSF12, PTK2, LOXL2, PRKX, TGFB1I1, STARD13, ABL1, DPP4, PRSS3, TGFBR1, S100P, SCG2, PTP4A3, ITGB2, CALCA, CDH13, PECAM1, NRP1, PLEKHG5, PLXND1, PAXIP1, GREM1 |
| endothelial cell morphogenesis | biological process | CLIC4, CNMD, NOTCH4, PLOD3, COL18A1, PECAM1, ARHGEF26 |
| endothelial cell proliferation | biological process | HMOX1, BMPR2, NOX5, THAP1, XBP1, LOXL2, CD34, PRKX, SCARB1, TEK, ANGPT4, APOA1, DLG1, ERN1, MMP14, CALCA |
| endothelial cell-cell adhesion | biological process | CYP1B1, CCN3, JUP, THBS4 |
| endothelial cell-matrix adhesion | biological process | ADAMTS9, PECAM1 |
| endothelial tip cell fate specification | biological process | DLL1, NRP1 |
| endothelial to hematopoietic transition | biological process | YTHDF2 |
| endothelial tube lumen extension | biological process | STARD13 |
| endothelial tube morphogenesis | biological process | CTNNB1, CSNK2B, CXCR4, PRKD2, CCM2, ACVRL1 |
| endothelin maturation | biological process | ECE1 |
| endothelin receptor signaling pathway | biological process | EDNRA, BCAR1, EDNRB, BCAR3, EDN1, PTK2B, CRKL |
| endothelium development | biological process | KDR, GJA1, CD34, SLC40A1, GJA5, GJA4 |
| energy derivation by oxidation of organic compounds | biological process | ACADVL, ACSM1 |
| energy homeostasis | biological process | STAT3, LEPR, PIK3CA, NR1D2, MEX3C, OMA1, PASK, CRTC3, PPARGC1A, MRAP2, PRCP, AMPD2, NMU, MFSD2A, PRKAA2, AMPD3, FLCN, IRX3, DLL1, NR4A3, UBB, ACACB, SLC35D3, METRNL, CRTC1, CD36, SGIP1 |
| energy reserve metabolic process | biological process | GNAS, LEP, MTOR, LEPR, MYC, GFPT1, MRAP2, ADRB3, PID1, MT3, KL, PRLH, ADGRF5 |
| engulfment of apoptotic cell | biological process | XKR4, MEGF10, RHOG, THBS1, RHOBTB3, RAC1, RAC2, XKR6, ADGRB1, XKR8 |
| enkephalin processing | biological process | PCSK2 |
| enteric nervous system development | biological process | SOX10, EDNRA, GDNF, PHOX2B, EDNRB, PHOX2A, RET, HLX, PHACTR4, KIF26A, TLX2 |
| enteric smooth muscle cell differentiation | biological process | EDNRB |
| enterobactin transport | biological process | ASIC3 |
| enteroendocrine cell differentiation | biological process | NEUROD1 |
| entrainment of circadian clock | biological process | CLOCK, PER1, GNA11, GNAQ, ID2, PHLPP1 |
| entrainment of circadian clock by photoperiod | biological process | TP53, PER3, PER1, RBM4B, OPN5, BHLHE40, PPP1CB, PER2, NR2F6, USP2, FBXL3, RBM4, PML, CRY1, ID2, PDE6B, SIK1, CRY2, CRTC1 |
| entry into host cell | biological process | CCR5, env |
| entry of bacterium into host cell | biological process | CTNND1, GRB2, CBL, CBLL1 |
| entry of symbiont into host cell by promotion of host phagocytosis | biological process | ITGAV |
| entry of viral genome into host nucleus through nuclear pore complex via importin | biological process | KPNA2, KPNA6 |
| enucleate erythrocyte development | biological process | MAEA |
| enucleate erythrocyte differentiation | biological process | RB1, CEBPG, SP3, MB, ID2 |
| enzyme active site formation via cysteine modification to L-cysteine persulfide | biological process | MOCS3 |
| enzyme active site formation via L-cysteine sulfinic acid | biological process | PARK7 |
| enzyme linked receptor protein signaling pathway | biological process | ERBB2, AXL, GAS6, JAK2, GP6, SYK, CD4, JAK3 |
| enzyme-directed rRNA 2'-O-methylation | biological process | FTSJ3 |
| enzyme-directed rRNA pseudouridine synthesis | biological process | DKC1, TSR3, RPUSD1 |
| eosinophil chemotaxis | biological process | CCL5, CCL8, CCL1, CCL3, HRH1, CCL11, CCL18, SCG2, CCL23, CCL3L1, CCL7, CCL2, CCL15 |
| eosinophil degranulation | biological process | CCL3, VAMP8, VAMP7 |
| eosinophil differentiation | biological process | IL25, GATA1 |
| eosinophil fate commitment | biological process | GATA2, GATA1 |
| eosinophil homeostasis | biological process | MPL |
| eosinophil migration | biological process | EPX |
| ephrin receptor signaling pathway | biological process | MMP2, MMP9, YES1, SRC, ACTB, CDC42, PTPN11, NTRK1, WASL, RASA1, ARPC1A, ACTR3, ARPC3, KALRN, CHN1, AP2S1, GRIN1, ARHGEF7, APH1B, PSENEN, NCK1, VAV3, ARPC5, EFNA1, EPHB2, PTK2, APH1A, ROCK2, SDC2, SS18, NCK2, AP2A2, ANKS1A, GIT1, EFNA5, EPHB1, ROCK1, AP2M1, PSEN1, EPHA6, TIAM1, CDK5R1, ARHGEF28, SDCBP, RAC1, AP2B1, VAV2, ACTG1, EFNA2, LYN, EPHA4, ACTR2, GRIN2B, EPHA1, EFNB1, NGEF, PAK3, EPHA2, EFNB2, EPHA7, HRAS, PSEN2, EFNB3, EPHA3, EPHA8, CRK, ARPC4, ARPC1B, DNM1, AP2A1, EPHB3, EPHB4, EPHA10, ITSN1, EFNA3, ANKS1B, EPHB6 |
| epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification | biological process | NODAL |
| epiboly involved in gastrulation with mouth forming second | biological process | MEGF8 |
| epicardium morphogenesis | biological process | ALPK2, TGFBR1 |
| epidermal cell differentiation | biological process | OVOL2, KLF4, HDAC2, SPINK5, OVOL1, GLI1, GLI2 |
| epidermal cell division | biological process | TP63 |
| epidermal cell fate specification | biological process | PTCH2, RBPJ, PTCH1 |
| epidermal growth factor catabolic process | biological process | SNX5, RAB7A |
| epidermal growth factor receptor signaling pathway | biological process | EGFR, EGF, TGFB1, SOX9, SRC, PIK3CA, PTPN11, SOS1, AREG, ARF4, ERBIN, PIK3C2A, IQGAP1, CAMLG, TDGF1, PIK3R1, SHC1, SOCS5, TGFA, PTK2, BRAF, FAM83B, NCK2, BCAR1, SLC30A10, KIF16B, PIGR, GRB7, PLCE1, EREG, GRB2, GAB1, ABL1, CBL, HBEGF, REPS2, RPS6KA5, BTC, GAREM1, PDPK1, DGKD, PTK2B, SHC3, VIL1, FAM83A, EFEMP1 |
| epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade | biological process | RASSF2 |
| epidermis development | biological process | EGFR, PLOD1, INSR, TP63, ATP2A2, CCN2, TFDP1, OVOL2, IFT74, LCE3A, ZNF750, ZMPSTE24, AGPAT2, FABP5, SCEL, ALDH3A2, NTF4, SPRR1A, YBX1, COL7A1, LCE2C, FOXN1, TGM5, NOTCH1, EMP1, ATP2C1, LAMC2, SPRR3, KRTAP5-9, LCE1F, PTCH2, GJB5, KRT32, OVOL1, DSP, SATB1, SHARPIN, POU3F2, RBP2, SPRR1B, S100A7, SPRR2B, GRHL1, LCE2B, LCE1C, EVPL, CALML5, PTHLH, FGF7, KRT83, HOXB13, KLK5, WAS, KRT85, LAMB3, CST6, LCE1D, EDAR, SPRR2D, KRT9, KRTDAP, LAMA3, LCE4A, CERS3, KRT15, ACER1, EDA2R, COL17A1, KRT14, KRT2, PPARA, PTCH1, EVPLL, CRABP2, GRHL3, IFT172, UGCG, LCE3D, FGF10, STS, DCT, KLK7, LCE3E |
| epidermis morphogenesis | biological process | FGFR2, CDC42, KLF4, WNT10A, PLOD3, FGF10 |
| epididymis development | biological process | GJB1, PTPN6, GJB5 |
| epinephrine biosynthetic process | biological process | TH |
| epinephrine metabolic process | biological process | ATP7A |
| epinephrine transport | biological process | SLC22A1 |
| epinephrine uptake | biological process | SLC22A3 |
| epithelial cell apoptotic process | biological process | EXOC5 |
| epithelial cell apoptotic process involved in palatal shelf morphogenesis | biological process | JAG2 |
| epithelial cell development | biological process | ESR1, TP63, SHROOM3, CXCR4, E2F4, HYDIN, ONECUT2, B4GALT1, ONECUT1 |
| epithelial cell differentiation | biological process | NR5A2, VEGFA, WT1, CASP6, CDK1, FGFR2, BMP7, GSTK1, PCNA, EZR, PPARG, PGK1, TP63, ANXA4, VDAC1, ACTL8, ANXA7, SPINK5, CTSB, CES1, HNRNPH3, CPT1A, CNN3, DHRS9, COL4A1, AKR1C2, FZD2, GSTA1, DNPH1, ID3, PTER, DMBT1, UPK1A, TGFB1I1, CBR1, ACADVL, BDH2, TOLLIP, TPP1, DLX6, TST, EHF, F11R, SULT1B1, SIX1, FN3K, CBFA2T2, TAGLN2, DLX5, ALDOC, GDF7, RHCG, KRT14, CDHR2, FZD1, UPK3A, UPK1B, GSTA2, VIL1, AKR1C1, FGF10 |
| epithelial cell differentiation involved in mammary gland alveolus development | biological process | HIF1A, ID2, FOXB1, FOXF1 |
| epithelial cell differentiation involved in prostate gland development | biological process | CTNNB1, PSAP |
| epithelial cell fate commitment | biological process | ARX |
| epithelial cell maturation | biological process | GJA1, AKR1B1, XBP1, TMEM79, FEM1B, TFCP2L1, SIX3 |
| epithelial cell maturation involved in prostate gland development | biological process | FOXA1, FEM1B, HOXB13 |
| epithelial cell maturation involved in salivary gland development | biological process | XBP1 |
| epithelial cell migration | biological process | NANOS1, PKN2, PKN3, PKN1, FAT2 |
| epithelial cell morphogenesis | biological process | SIPA1L3, PALLD, FAT1, VSIG1, FLNB, RAB25, BCL11B, POF1B, EPB41L5, RILPL2, HRH2, IHH, RILPL1, DACT2 |
| epithelial cell morphogenesis involved in placental branching | biological process | SPINT2, ST14 |
| epithelial cell proliferation | biological process | HNF1B, KIT, LGR4, PURA, COL8A1, PSEN1, RETNLB, EHF, C6orf89, FABP7, COL8A2, FGF10 |
| epithelial cell proliferation involved in lung morphogenesis | biological process | BMP4, MAP2K1 |
| epithelial cell proliferation involved in mammary gland duct elongation | biological process | ESR1, AREG |
| epithelial cell proliferation involved in prostatic bud elongation | biological process | SOX9 |
| epithelial cell proliferation involved in renal tubule morphogenesis | biological process | LGR4, MEF2C, MTSS1, LGR5 |
| epithelial cell proliferation involved in salivary gland morphogenesis | biological process | TNF, IL6, FGFR2, SHH, NKX3-1, FGF10 |
| epithelial cell-cell adhesion | biological process | CDC42, ITGB5, CTNNA1, BVES, DSP, KIFC3, VCL, SRF, SERPINB8, IHH, CAMSAP3 |
| epithelial cilium movement | biological process | CABYR, ROPN1L, ADCY10, DNAH1, SPA17, LRRC6, NME5, DPCD, STK36, TTLL1, DNAAF4, KIF27, GAS8, CCDC40 |
| epithelial cilium movement involved in determination of left/right asymmetry | biological process | CCDC103, OFD1, LRRC6, DNAAF1, CFAP53, RFX3, NPHP3, CCDC40 |
| epithelial fluid transport | biological process | AHCYL1, EDNRB, ITPR1, EDN1, SLC26A6 |
| epithelial structure maintenance | biological process | CRACD, CXADR, SRF, LDB2, CROCC |
| epithelial to mesenchymal transition | biological process | TGFB1, SOX9, HIF1A, FGFR2, GSK3B, BMP7, CTNNB1, TGFBR3, HGF, RFLNB, DLG5, S100A4, FAM83D, LOXL2, HNRNPAB, WNT4, NOTCH1, MSX1, HMGA2, EPB41L5, TGFB2, RBPJ, TGFBR1, DDX17, LEF1, NOTCH4, WNT11, CUL7, LOXL3, FOXF2, BMP2, AKNA, ENG, AKNAD1 |
| epithelial to mesenchymal transition involved in cardiac fibroblast development | biological process | SPRY1, PDCD4 |
| epithelial to mesenchymal transition involved in endocardial cushion formation | biological process | FGF8, SMAD4, NOTCH1, MSX1, RBPJ, TMEM100, HEY2, MSX2, ENG |
| epithelial tube branching involved in lung morphogenesis | biological process | SOX9, CTNNB1, BMP4, SHH, HOXA5, DLG5, KRAS, FOXA1, RSPO2, ESRP2, CTSZ, FOXF1, DAG1, HHIP, FGF10, NKX2-1 |
| epithelial tube formation | biological process | PODXL |
| epithelial tube morphogenesis | biological process | PRKX, GREB1L |
| epithelial-mesenchymal cell signaling | biological process | BMP4, CDC42, SHH, SMO, WNT6 |
| epithelial-mesenchymal signaling involved in prostate gland development | biological process | SHH, FOXA1 |
| epithelium development | biological process | HNF1B, BMP4, CHD7, FOXJ1, LHX1, RARG |
| epoxide metabolic process | biological process | EPHX4, EPHX1 |
| epoxygenase P450 pathway | biological process | CYP1A1, CYP1A2, CYP2B6, EPHX2, CYP1B1, CYP2J2, CYP4A11, CYP2A7, CYP2C8, CYP2A6, CYP2C19, CYP2C18, CYP4F12, CYP2E1, CYP4F2, CYP2S1, CYP2C9 |
| equilibrioception | biological process | USH1G, USH1C, MYO7A, CDH23, PCDH15 |
| ER overload response | biological process | TP53, GSK3B, HSPA5, WFS1, SELENOS, DDIT3, ATG10, CCDC47, EIF2AK3 |
| ER to Golgi ceramide transport | biological process | PLEKHA3, CERT1, PLEKHA8, SGPP1 |
| ER to Golgi vesicle-mediated transport | biological process | F10, BGLAP, GAS6, SERPINA1, F5, ANK1, DYNC2H1, DYNLL1, DYNC1H1, GOPC, USO1, AREG, ARF4, ARCN1, ACTR10, NRBP1, TMED5, SEC23B, SEC22C, SAR1A, RAB29, ZW10, SEC22B, CD55, KDELR2, ANK3, TRAPPC12, USE1, SEC31A, GOSR1, COPB2, COPB1, COPZ1, RAB1A, LMAN2L, SPTBN5, SEC16A, KDELR3, VAPB, TGFA, PROC, NSF, SEC24C, SEC13, RAB2A, STX5, SCFD1, ERGIC2, VTI1B, DYNC1I1, TRAPPC3, CAPZA1, CTSC, DYNC1I2, MCFD2, BET1L, COPE, DCTN3, CNIH1, F7, CD59, TRAPPC11, RANGRF, DCTN6, LMAN1, SPTBN1, COL7A1, LMAN2, KLHL12, SEC22A, DCTN5, PROS1, CNIH3, TMED6, TFG, TBC1D20, COG4, DYNC1LI2, STX17, CREB3L2, ARFGAP1, GORASP1, SAR1B, TMED2, TEX261, PGAP1, VAMP4, GOLT1A, VAPA, SPTBN2, PDCD6, ANK2, YIF1B, TRAPPC3L, TRAPPC5, COPG1, BET1, SEC24B, BCAP31, SEC23A, ATL3, DYNC1LI1, CTAGE8, CAPZA2, VAMP7, TICAM2, CTAGE4, ARFGAP3, CNIH4, TMED7, GOSR2, SEC24D, TMED10, DCTN2, MIA3, COG8, TRAPPC2L, TRAPPC2, TRAPPC2B, CAPZB, COPA, ACTR1A, GOLGB1, BCAP29, DCTN4, IER3IP1, F8, SPTB, NAPA, SPTAN1, CTAGE1, HYOU1, KDELR1, COG7, TMED4, COG1, TMED9, TRAPPC4, VTI1A, COG3, |
| ER-associated misfolded protein catabolic process | biological process | DERL1, SDF2L1, UFD1, RNF185, UGGT1, AUP1, UGGT2 |
| ER-associated ubiquitin-dependent protein catabolic process | biological process | MAN1B1, HSPA5, WFS1, UBXN4, SELENOS, DERL2, ERLIN1, PSMC6, UBE4A, DNAJC10, SGTA, TRIM13, TRIM25, FAF2, FBXO17, DERL1, DNAJB12, HSP90B1, STT3B, DNAJB9, JKAMP, FBXO2, TMUB2, STUB1, UFD1, HERPUD1, RNF175, SEL1L2, SEC61B, DNAJB14, TMEM129, RNF103, SEL1L, TMEM67, YOD1, RHBDD2, UBE2J2, CCDC47, ERLEC1, FBXO6, RNF185, DNAJC18, ERLIN2, UBE4B, OS9, SYVN1, MARCHF6, RNF121, EDEM1, AUP1, UBXN8, FOXRED2, TMUB1, FBXO44, DNAJB2, DERL3, NPLOC4, AMFR |
| ER-dependent peroxisome localization | biological process | PEX16 |
| ER-dependent peroxisome organization | biological process | PEX16 |
| ER-nucleus signaling pathway | biological process | ATP2A2 |
| ERAD pathway | biological process | BRSK2, DERL1, DNAJB12, PRKN, UBXN6, RHBDD1, SEL1L, RNF139, CCDC47, ERLEC1, RNF185, SYVN1, MARCHF6 |
| ERBB signaling pathway | biological process | MAPK1, NRG1, PTPN11, MVP |
| ERBB2 signaling pathway | biological process | EGFR, EGF, ERBB2, HSP90AA1, AKT1, SRC, PIK3CA, NRG1, SOS1, USP8, ERBIN, PTPRR, CPNE3, PIK3R1, SHC1, NRG4, STUB1, GRB7, CUL5, EREG, NRG2, GRB2, GAB1, HBEGF, ERBB3, BTC, PTPN12, PTPN18, MATK, PTK6, CDC37 |
| ERBB2-ERBB3 signaling pathway | biological process | MYOC |
| ergosterol biosynthetic process | biological process | CYP26A1, CYP26C1 |
| ERK1 and ERK2 cascade | biological process | EGF, SOX9, MAPK3, MAPK1, IGF1, ITGAV, OXTR, KARS1, LGALS9, IQGAP3, CCL11, YWHAZ, APOA1, MAP2K2, ZFP36L2, PTGER4, ZFP36L1, MT3, MAP2K1, AVP, SULT1A3, CTSH, AGT, FGF10, HTR2B |
| ERK5 cascade | biological process | MEF2A, MAP2K5 |
| error-free postreplication DNA repair | biological process | UBE2V2 |
| error-free translesion synthesis | biological process | PCNA, REV1, POLH, RPA2, RFC4, RFC5, RFC3, RPS27A, RPA1, UFD1, RCHY1, UBC, RPA3, UBA52, RFC2, SPRTN, UBB, POLD1, NPLOC4, RFC1 |
| error-prone translesion synthesis | biological process | PCNA, REV1, REV3L, POLH, RPA2, RFC4, RFC5, RFC3, RPS27A, RPA1, POLK, POLI, UBC, RPA3, MAD2L2, UBA52, RFC2, UBB, PRIMPOL, RFC1 |
| erythrocyte development | biological process | SH2B3, BCL6, LYAR, MAEA, BPGM, SOX6, TMOD3, SRF, NCKAP1L, DMTN, ALAS1, SLC4A1, RHAG, ADGRF5, GATA1 |
| erythrocyte differentiation | biological process | INHBA, CASP3, KIT, BMP4, INHA, ETV2, RPS14, IKZF1, TMEM14C, JAK2, AHSP, DYRK3, SPI1, SLC25A38, FLVCR1, MPIG6B, RPS19, ADAR, PTPN2, SFXN1, ACIN1, SP3, GATA3, TRIM10, ATP5IF1, HIPK2, LYN, SOX6, KMT2E, EPAS1, HCLS1, PKNOX1, DNASE2, ADD1, NFE2L1, MFHAS1, EPO, JAK3, THRA, NCAPG2, ZFPM1, C15orf41, SMAD5, GATA1 |
| erythrocyte homeostasis | biological process | HMOX1, AXL, PRDX1, IREB2, RPS24, HOXB6, RPS17, AMPD3, NCKAP1L, KLF2 |
| erythrocyte maturation | biological process | ERCC2, G6PD, FLVCR1, EPB42, MAEA, HBZ, BRD1, PTBP3, FAM210B, ZBTB7A, KLF2, EPO, L3MBTL3 |
| erythropoietin-mediated signaling pathway | biological process | KIT, EPOR, EPO |
| ESCRT III complex assembly | biological process | CHMP6 |
| ESCRT III complex disassembly | biological process | CHMP2A, CHMP5, VTA1, VPS4B, IST1, CHMP1A, CHMP7, CHMP1B |
| esophagus smooth muscle contraction | biological process | SULF1, SULF2 |
| establishment of anatomical structure orientation | biological process | TTC8 |
| establishment of animal organ orientation | biological process | IRX4 |
| establishment of apical/basal cell polarity | biological process | FOXJ1, SCRIB, FSCN1 |
| establishment of bipolar cell polarity involved in cell morphogenesis | biological process | CRB1 |
| establishment of blood-brain barrier | biological process | LSR, MFSD2A |
| establishment of blood-nerve barrier | biological process | HAPLN2, CLDN1 |
| establishment of blood-retinal barrier | biological process | CLDN5, MFSD2A |
| establishment of body hair planar orientation | biological process | ASTN2, CELSR1, VANGL2, FZD6 |
| establishment of cell polarity | biological process | WEE1, GSK3B, BRSK2, SHH, PKD1, KIF26B, RAB11FIP2, MARK2, ARHGEF11, PTK2, JAM3, MPP7, ALPK2, NEK3, PARD3B, WWC1, FEZ1, EPHB1, SDCCAG8, PARD3, MAP2, PRKCZ, FAM89B, CRK, TCIRG1, BRSK1, WNT7A, CRKL, UST |
| establishment of cell polarity involved in ameboidal cell migration | biological process | AMOT, AMOTL2, AMOTL1 |
| establishment of centrosome localization | biological process | EZR, PARD3B, PARD3, MAD2L1, DLG1, MISP, FHOD1, CEP83 |
| establishment of chromosome localization | biological process | BIRC5, NDE1 |
| establishment of endoplasmic reticulum localization to postsynapse | biological process | MYO5A |
| establishment of endothelial barrier | biological process | ICAM1, EZR, RAP1A, RAPGEF2, SOX18, ROBO4, RAPGEF1, MSN, PPP1R16B, RDX, PDE4D, MYADM, RAPGEF3, PECAM1, PDE2A, RAP1B |
| establishment of epithelial cell apical/basal polarity | biological process | EZR, PTK7, SLC9A3R1, MYO9A, MSN, OPHN1, RAP2A, FOXF1, SYNE4, TCF15, SH3BP1, CAMSAP3 |
| establishment of epithelial cell polarity | biological process | SIPA1L3, CYTH3, HES1, FERMT1, PARD3, FRMD4B, FRMD4A, ARF6, CLASP1, FBF1, CYTH1 |
| establishment of glial blood-brain barrier | biological process | MXRA8 |
| establishment of Golgi localization | biological process | CDC42, PDCD10, STK25, SLC9A3R1, YWHAZ, COPG1, ARHGAP21, RIPOR1 |
| establishment of integrated proviral latency | biological process | LIG4, XRCC5, PSIP1, XRCC6, XRCC4, PPIA |
| establishment of left/right asymmetry | biological process | ENKUR |
| establishment of localization in cell | biological process | ZWINT, GRIK5 |
| establishment of macromolecular complex localization to telomere | biological process | ATM, ATR |
| establishment of meiotic spindle localization | biological process | SPIRE1, MYH9, SPIRE2, FMN2 |
| establishment of meiotic spindle orientation | biological process | MOS |
| establishment of melanosome localization | biological process | RAB17, SHROOM2 |
| establishment of mitochondrion localization | biological process | FEZ1, MARK1 |
| establishment of mitochondrion localization by microtubule attachment | biological process | RHOT1 |
| establishment of mitotic sister chromatid cohesion | biological process | NAA50, NIPBL |
| establishment of mitotic spindle localization | biological process | NUSAP1, ESPL1, CLASP2, CLASP1 |
| establishment of mitotic spindle orientation | biological process | DYNLT1, ACTR10, BCCIP, GPSM2, ZW10, NDC80, SPDL1, CDK5RAP2, SPRY1, MCPH1, PLK1, MAD2L1, NSFL1C, NUMA1, UBXN2B, ARHGEF2, ACTR1A, TBCB, SPRY2, HTT, NDE1, ACTR1B, CENPA, MISP, SAPCD2, FGF10 |
| establishment of monopolar cell polarity | biological process | GBF1, MAP1B |
| establishment of natural killer cell polarity | biological process | SNX27 |
| establishment of neuroblast polarity | biological process | DOCK7 |
| establishment of organelle localization | biological process | ATP6AP1, CROCC |
| establishment of planar polarity | biological process | TP63, PTK7, CPLANE1, INTU, FZD3, CELSR1, VANGL2, EXOC5, DLG3, FZD6, FUZ, GRHL3, RPGRIP1L |
| establishment of planar polarity involved in nephron morphogenesis | biological process | WNT9B |
| establishment of planar polarity involved in neural tube closure | biological process | VANGL2, CTHRC1 |
| establishment of planar polarity of embryonic epithelium | biological process | CELSR1, FOXF2 |
| establishment of planar polarity of follicular epithelium | biological process | WDR1 |
| establishment of protein localization | biological process | MDM2, AKAP4, DZIP1, SELENOS, CHMP2A, ANK3, CEP55, DERL1, CORO1C, KIF14, PLEKHA1, NRXN1, USH2A, IST1, RCC2, ITGA2, PLK1, PHLDB2, CRIPT, ABL1, ADGRV1, RDX, DLG4, RAP2A, MCC, HINFP, TREX1, WBP2, WHRN, PDZD7, RIPOR2, ITGA8, CHMP1B |
| establishment of protein localization to chromatin | biological process | LRWD1, MACROH2A2, RUVBL2, NIPBL, MACROH2A1, SGF29, H1-5 |
| establishment of protein localization to endoplasmic reticulum | biological process | RYR2 |
| establishment of protein localization to endoplasmic reticulum membrane | biological process | RAB3GAP2, RAB3GAP1 |
| establishment of protein localization to juxtaparanode region of axon | biological process | CNTN2 |
| establishment of protein localization to membrane | biological process | RAB11A, BRAF, FRMPD1, BID, CALM3, RAB11B, NPC1 |
| establishment of protein localization to mitochondrial membrane | biological process | CALM3 |
| establishment of protein localization to mitochondrial membrane involved in mitochondrial fission | biological process | AP3B1 |
| establishment of protein localization to mitochondrion | biological process | AKT1, DDIT3, PINK1, HK2 |
| establishment of protein localization to organelle | biological process | TSPAN10, RAB11A, LAMP3, LAMP2, LAMP1, IFT122 |
| establishment of protein localization to peroxisome | biological process | PEX19 |
| establishment of protein localization to plasma membrane | biological process | GORASP1, AFDN |
| establishment of protein localization to plasma membrane | biological process | TNF, TNFRSF1A, CDH1, EZR |
| establishment of protein localization to postsynaptic membrane | biological process | RAPSN |
| establishment of protein localization to telomere | biological process | BRCA2, TERT, POT1, ACD, NABP2 |
| establishment of RNA localization to telomere | biological process | ATM, ATR |
| establishment of Sertoli cell barrier | biological process | ICAM1 |
| establishment of sister chromatid cohesion | biological process | DDX11 |
| establishment of skin barrier | biological process | KRT1, CYP26B1, TP63, TMEM79, ABCA12, LSR, STMN1, STARD7, FLG, SFN, FA2H, GRHL1, ALOXE3, KDF1, CLDN1, ELOVL1, CLDN4, ALOX12B, HRNR, GRHL3, UGCG |
| establishment of spindle localization | biological process | DYNC1H1 |
| establishment of spindle orientation | biological process | MAP4, LLGL1, LLGL2, KIF25, CLASP1 |
| establishment of synaptic specificity at neuromuscular junction | biological process | F2R, GPHN |
| establishment of T cell polarity | biological process | CYP26B1, SCRIB, CCL19, CRTAM, CCR7, MYH9, DOCK2, CCL21 |
| establishment of vesicle localization | biological process | RAB11A, RAB7A, IKBKG, TCIRG1 |
| establishment of viral latency | biological process | CREB3, IRF7 |
| establishment or maintenance of actin cytoskeleton polarity | biological process | ARHGAP35, PDLIM1, MAPKAP1, AQP1 |
| establishment or maintenance of apical/basal cell polarity | biological process | EZR, CDC42, CLIC4, OOEP |
| establishment or maintenance of cell polarity | biological process | GSK3B, CDC42, ACTR3, FAT1, RHOU, CTNNA1, STK25, SPINT2, RHOG, PARD3, FSCN3, CD3G, RHOQ, DLG1, RHOBTB3, RAC1, RAC2, PARVG, CRB1, PARVB, PARD6A, ACTR2, PARD6B, PARVA, CDC42BPB, CLASP2, RAC3, SPN, SFRP5, RHOJ, RHOV, FSCN2, CARMIL2, CAP2, FSCN1, KIAA1614, CLASP1, PARD6G, CAP1, RPGRIP1L |
| establishment or maintenance of cell polarity regulating cell shape | biological process | MARK2, PARVB |
| establishment or maintenance of epithelial cell apical/basal polarity | biological process | ARF4, ERBIN, FAT1, MARK2, DLG5, LRRC1, PARD3B, SCRIB, PARD3, DLG1, VANGL2, CRB1, ILK, DLG3, CDX2, CRB2, MTCL1, DLG2, SYNJ2BP |
| establishment or maintenance of microtubule cytoskeleton polarity | biological process | CKAP5, CAMSAP3 |
| establishment or maintenance of monopolar cell polarity | biological process | CARMIL2 |
| establishment or maintenance of polarity of embryonic epithelium | biological process | WNT7B |
| establishment or maintenance of transmembrane electrochemical gradient | biological process | BAX, BAK1, ATP1A4, ATP1A3, ATP1A2, ATP1B1, FXYD2, ATP1A1, ATP1B2, ATP4A, ATP1B3, SLC22A1, ATP4B |
| estrogen biosynthetic process | biological process | CYP19A1, HSD17B1, HSD3B1, STAR, HSD17B7, HSD17B8, HSD17B14, HSD17B11, HSD17B12, DHRS11, RDH8 |
| estrogen metabolic process | biological process | IL1B, HSD17B1, HSD17B4, SULT1E1, SULT1A1, COMT, CYP1B1, PLEKHA1, UGT2B11, HSD17B8, CYP2C8, TIPARP, CYP3A5, PDGFRA, CYP2D6, CYP2C9 |
| estrous cycle | biological process | ESR2, GNRH1, CLU, MMP7, OXTR, PTN, ANXA1, EGR1, ADNP, MDK, HAS2, ETS1, NCOA1, NCOR2, OPRL1, HAS1 |
| ethanol catabolic process | biological process | ALDH2, SULT1B1, SULT1C4, SULT1A3, ALDH3B1, SULT1A2 |
| ethanol metabolic process | biological process | ADH4 |
| ethanol oxidation | biological process | ADH4, ADH5, ADH1A, ADH6, ADH1B, ALDH2, ACSS1, ALDH1A1, ACSS2 |
| ethanolamine metabolic process | biological process | CHKA, GDE1 |
| ether lipid biosynthetic process | biological process | PEX7, AGPS, DHRS7B, GNPAT, FASN, FAR1, TMEM189 |
| ether lipid metabolic process | biological process | PLAAT3, AGMO, TMEM86B, NCEH1 |
| ethylene metabolic process | biological process | CYP1A1 |
| eukaryotic translation initiation factor 2 complex assembly | biological process | CDC123 |
| eukaryotic translation initiation factor 4F complex assembly | biological process | EIF4B |
| evasion or tolerance by virus of host immune response | biological process | env, SCRIB, EIF2AK2 |
| evasion or tolerance of host defenses by virus | biological process | TGFB1 |
| excitatory chemical synaptic transmission | biological process | GRIN1, GRIN2C, PTCHD1, GRIN2B, SSH1, PDLIM4, GRIN2A, GRIN2D, SHISA6 |
| excitatory postsynaptic potential | biological process | GHRL, CHRNA5, CHRNE, GRIN1, MPP2, CHRNA2, DGKI, MEF2C, GLRA3, CHRNB1, CHRNA7, CHRND, CHRNA10, CHRNA3, MECP2, GRIN2C, PPP3CA, GRIK5, NPFF, GRIN2B, P2RX7, PPP1R9A, P2RX6, GLRA1, CHRNA6, GRID2, HCRT, CDK5, CHRNG, GRIN2A, RAB3GAP1, P2RX4, CHRNB2, CHRNA4, P2RX5, SLC29A1, DRD2, ARRB2, P2RX3, MAPK8IP2, NPAS4, ADORA2A, SEZ6, P2RX2, GRIN2D, GRIK2, CHRNA1, GLRA2, CHRNB4, LRRK2, SLC17A7, TRPV1 |
| excitatory synapse assembly | biological process | NPTN, LRRC4, GRID2, PLXNB2, WNT7A |
| excretion | biological process | HMOX1, SLC22A18, NPHP1, AQP5, AQP7, ATP6V1B1, SLC26A3, GRHPR, KIRREL1, CLCNKA, AQP9, CLDN16, UMOD, SCNN1G, CLCNKB, NEDD4L, AMN, POU3F3, TACR2, NFAT5, MLLT6, ATP6V0A4, AVPR2, AQP6, GUCA2B, ADORA2B, NPHS1, SCNN1B, KCNJ1, UGT1A7, CLCN5 |
| execution phase of apoptosis | biological process | AKT1, CASP3, CASP8, BNIP1, HTRA2, COLEC11, CASP2, CASP7, TAOK1, MADD, AIFM3, CIDEB, BBC3 |
| execution phase of necroptosis | biological process | RIPK3 |
| exit from mitosis | biological process | CHMP2A, CHMP4B, EPS8, PPP2R2D, CLASP2, CHMP7, UBE2C, CLASP1, CTDP1, UBE2S, SPAST |
| exocrine pancreas development | biological process | INSR, XBP1, WLS, PDX1, SRP54, PTF1A |
| exocrine system development | biological process | RAB26 |
| exocyst localization | biological process | STXBP6, EXOC3, EXOC1, EXOC3L2, TNFAIP2, EXOC3L1 |
| exocytic insertion of neurotransmitter receptor to postsynaptic membrane | biological process | STX3, CPLX1, STX1B, SNAP25, SNAP47 |
| exocytosis | biological process | BRSK2, CCL5, ANK1, MYH10, RAB11A, SNX19, RIMS2, ARFGEF1, PIK3C2A, CCR1, CCL8, RAB3IP, EXOC6B, SNAP23, RAB27A, RALA, NSF, RIMS1, LIN7C, WASHC3, SNAPIN, CCL3, STX3, CPLANE2, ARFGEF2, CPLX1, RAB25, SYTL4, LIN7A, STXBP6, STXBP5, MYO5A, SNAP29, SYCN, EXOC6, CADPS, GCGR, PRSS12, STX1B, DOC2A, MICAL3, SCAMP1, SNAP25, LLGL1, SYTL3, EXOC3, KCNB1, VAMP3, RAB11B, UNC13C, CADPS2, EXOC5, UNC13B, VAMP7, SNAP47, SYTL2, MIA3, EXOC8, EXOC4, DNAJC5, EXOC1, STXBP3, LGI3, EXOC3L2, LLGL2, RAB3IL1, UNC13D, HCK, CDK5, SCRN1, STX4, STX11, TNFAIP2, SYTL1, RIMS3, EXOC7, RAB3D, NKD2, PIP5K1C, TRIM72, UNC13A, MYO1G, SYT7, BAIAP3, ITSN1, STXBP2, SLC17A9, SRCIN1, RPH3AL, ARHGAP44, SYT10, EXOC2, STXBP5L, HAP1, SYT16, CPLX2, EXOC3L1, CPLX3, RIMS4, LIN7B, RAPGEF4 |
| exogenous drug catabolic process | biological process | NR1I2, CYP1A2, CYP2B6, CYP2J2, NUDT15, CYP2R1, CYP2A7, CYP2C8, CYP4B1, CYP2A6, CYP2C19, CYP2C18, CYP2E1, CYP2D6, CYP2S1, CYP2D7, CYP2W1, CYP2C9 |
| exon-exon junction complex disassembly | biological process | PYM1 |
| exonucleolytic catabolism of deadenylated mRNA | biological process | LSM1, LSM3, WDR61, CNOT8, EXOSC9, TTC37, NT5C3B, DCP2, EXOSC7, EDC4, DCP1B, EXOSC5, PATL1, DDX6, EXOSC1, EXOSC3, EXOSC8, DIS3, EDC3, EXOSC4, LSM6, DCP1A, LSM7, LSM2, SKIV2L, EXOSC6, DCPS, EXOSC2, LSM4 |
| exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | EXOSC9, EXOSC7, ERI1, EXOSC3, EXOSC8, ERI3, EXOSC2 |
| exosomal secretion | biological process | COPS5, RAB11A, TSG101, RAB27A |
| exploration behavior | biological process | LRRTM1, JPH3, ATXN3, CHL1, ABL2, ABAT, CHRNA4, BRINP1, ITGA3, EIF4A3, LRRK2 |
| export across plasma membrane | biological process | SLC22A2, SLC27A1, ABCC5, ABCC4, ABCG2 |
| extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration | biological process | SRGAP2, SRGAP2C |
| external genitalia morphogenesis | biological process | LRP6, NIPBL |
| extracellular exosome assembly | biological process | CD34 |
| extracellular exosome biogenesis | biological process | ATP13A2 |
| extracellular matrix assembly | biological process | TGFB1, GAS6, GPM6B, QSOX1, HAS2, SMPD3, COL1A2, HAPLN2, HAS3, HAS1 |
| extracellular matrix constituent secretion | biological process | CCN2, TMEM38B, ENG |
| extracellular matrix disassembly | biological process | TIMP1, DCN, MMP2, MMP9, CD44, ADAMTS5, A2M, MMP12, FN1, MMP7, CDH1, ELANE, TIMP2, LAMC1, CTSK, CAPN2, CTSV, CTSL, TPSAB1, CAPNS2, NOXO1, TLL2, CAPNS1, MMP15, CTSG, BMP1, MMP16, FLOT1, MMP14, KLK2, MMP20, EXOC8, TLL1, KIF9, CAPN1, CTSS, CAPG, LCP1, MMP13, SCUBE1, PLG, KLK5, MMP10, MMP19, ENG, FURIN, MMP11, ADAM8, HTRA1, SH3PXD2B, TMPRSS6, ADAMTS4, WDR72, CTRB1, MMP8, KLK4, KLK7 |
| extracellular matrix organization | biological process | TNF, ICAM1, DCN, MMP9, CD44, SOX9, VWF, SERPINE1, ERCC2, KDR, APP, ITGB1, ITGA5, PRDX4, ITGAV, ITGA4, ITGA6, FN1, CDH1, ADAMTS20, DDR1, CCN1, COL11A1, COL5A2, LAMC1, ITGAE, NOX1, MATN4, TNXB, CSGALNACT1, TNFRSF11B, VCAM1, FBN2, CD47, SPINK5, PDGFB, ITGA2B, ITGB5, BCL3, FBN1, COL9A3, SPP1, MFAP2, PTK2, JAM3, COL3A1, COL4A1, COL11A2, COL8A1, MFAP5, ST7, FGG, COL7A1, SPOCK2, BCAN, ADAMTS9, SPINT1, ITGA10, COL2A1, MMP15, WNT3A, MADCAM1, LAMA4, MIA, COL23A1, HPSE2, APBB2, SERAC1, MMP28, FBLN5, MMP23B, THBS1, COL4A2, ITGAM, LAMC2, ERO1A, ACAN, COL9A1, FBLN1, POSTN, FGB, ITGA2, ITGB6, COL4A6, SLC39A8, PDGFA, BGN, MMP16, NFKB2, COL4A3, COL24A1, ABI3BP, ECM2, ITGB3, COL1A2, ATXN1L, HAPLN1, ITGB4, LOX, GFOD2, COL6A1, MMP14, F11R, MMP20, B4GALT1, TNC, SERPINB5, ATP7A, TGFBI, ITGB8, HSPG2, ERO1B, MMP25, ITGAX, ITGB7, KAZALD1, EMILIN1, VTN, ITGB2, LAMB1, COL8A2, MMP13, MPZL3, MMP21, CRISPLD2, COL6A2, COL5A1, FOXF2, ITGA9, NID2, HSD17B12, EGFLAM, COL27A1, SMOC2, ICAM5, MATN3, FGA, MMP10, COL5A3, ICAM3, COL18A1, FOXF1, LAMB |
| extracellular matrix-cell signaling | biological process | NDP, FZD4, FER, LRP5 |
| extracellular negative regulation of signal transduction | biological process | ESR2, LRPAP1 |
| extracellular polysaccharide biosynthetic process | biological process | HAS2, HAS3, HAS1 |
| extracellular structure organization | biological process | TGFBR1 |
| extracellular transport | biological process | TSG101, WWP2, ARRDC1 |
| extracellular vesicle biogenesis | biological process | ARRDC4, ARRDC1 |
| extraocular skeletal muscle development | biological process | MYOM2, FOXL2, MYOM1 |
| extrathymic T cell selection | biological process | IL15 |
| extrinsic apoptotic signaling pathway | biological process | TGFB1, TNF, IFNG, INHBA, IL6R, TNFRSF1B, FAS, IL12A, BAX, FASLG, CASP8, CIB1, BAD, PARP2, IL33, JAK2, G0S2, ACVR1B, TNFSF12, MLLT11, RNF41, HIPK1, KRT18, FADD, BID, TGFB2, IFI27, PML, P2RX7, TNFRSF12A, TRADD, PIDD1, TNFRSF10A, SIVA1, KRT8, TLR3, PDPK1, SMAD3, WWOX, SGPP1 |
| extrinsic apoptotic signaling pathway in absence of ligand | biological process | IL1B, IL4, BCL2, KITLG, FAS, BAX, BAK1, BCL2L2, CASP3, GSK3B, CASP9, IL1A, BAD, ITGAV, IL2, MCL1, BCL2L11, BAG3, MKNK2, FADD, CASP2, DCC, BOK, ERBB3, BCL2L1, MOAP1, PYCARD, APPL1, FOXO3, BCL2L10, BCL2A1, EYA2 |
| extrinsic apoptotic signaling pathway via death domain receptors | biological process | TNF, BCL2, TNFRSF1A, FAS, BAX, FASLG, BAD, NGF, BEX3, BLOC1S2, DDX3X, DDX47, PIK3R1, DAB2IP, DEDD2, DEDD, BAG3, TNFRSF10B, FADD, BID, GABARAP, SORT1, DIABLO, DAPK1, TRADD, MOAP1, PIDD1, CASP8AP2, TNFRSF10A, NF1, CRADD, DELE1 |
| eye blink reflex | biological process | CACNG2 |
| eye development | biological process | BMP7, SOX2, FGF9, SIPA1L3, RAB18, PBX2, ZDHHC16, CRYGA, PBX3, HIPK1, ADAMTS18, FREM2, SLC39A5, MEIS3, ABCB5, PBX1, TGFB2, HIPK2, MAB21L2, SIX3, SALL2, BMP6, MEIS1, PBX4, MEIS2, GDF3, SIX6, FOXC1, RBP4, SH3PXD2B, HSF4, SCO2, SMOC1, FOXE3 |
| eye morphogenesis | biological process | COL5A2, NIPBL, COL5A1 |
| eye photoreceptor cell development | biological process | VEGFA, RPGRIP1, TULP1, PRDM1, MFRP, NR2E3, GNGT1, CRB1, RDH13, CEP290, TH, FSCN2, MYO7A, OLFM3 |
| eye photoreceptor cell differentiation | biological process | STAT3, PPP2R3A, NKD1 |
| eye pigment biosynthetic process | biological process | TYR, OCA2, GPR143 |
| eye pigment granule organization | biological process | SHROOM2 |
| eye pigmentation | biological process | ATP6AP2 |
| eyelid development in camera-type eye | biological process | EGFR, INHBA, SOS1, HDAC2, TFAP2A, SOX11, TWIST1, SRF, STRA6, GRHL3, OSR2 |
| face development | biological process | MAPK3, MAPK1, SOX3, RAF1, CHD7, ALDH1A2, ZFAND5, MKKS, BBS4, ALDH1A3, MAP2K1, SRF, HOXB3, RARG, RARA |
| face morphogenesis | biological process | TGFB1, MMP2, TGFB3, PTPN11, CLDN5, PLEKHA1, RRAS, ARID5B, SKI, MSX1, TIPARP, DKK1, LRP6, EP300, NIPBL, ANKRD11, CSRNP1, ASPH, LEF1, DLX5, CRISPLD2, CRISPLD1, PDGFRA, RAB3GAP1, MYH3, STRA6 |
| facial nerve morphogenesis | biological process | ADARB1, PLXNA4, SIX1 |
| facial nerve structural organization | biological process | SEMA3A, SEMA3F, NRP2, EGR2, PLXNA4, NRP1, HOXB2, PLXNA3 |
| facioacoustic ganglion development | biological process | SEMA3A, NRP2, NRP1 |
| Factor XII activation | biological process | F12 |
| FAD biosynthetic process | biological process | FLAD1 |
| FAD transmembrane transport | biological process | SLC25A17 |
| farnesol catabolic process | biological process | AKR1C3, AKR1B10 |
| farnesyl diphosphate biosynthetic process, mevalonate pathway | biological process | HMGCS2, HMGCS1 |
| farnesyl diphosphate metabolic process | biological process | FDFT1 |
| Fas signaling pathway | biological process | CASP8AP2 |
| fasciculation of motor neuron axon | biological process | EPHA4, EPHA3 |
| fasciculation of sensory neuron axon | biological process | MEGF8, EPHA4, EPHA3 |
| FasL biosynthetic process | biological process | PHLDA1 |
| fast, calcium ion-dependent exocytosis of neurotransmitter | biological process | SYT1 |
| fat cell differentiation | biological process | IL11, GSK3B, GPX1, INSR, FOXO1, BSCL2, TCF7L2, SENP2, ERAP1, KLF4, PIAS1, GRK5, BBS2, ANGPTL8, NOC3L, FBXO9, C1QTNF3, TMEM120A, MKKS, PSMB8, ARID5B, BBS9, SOCS1, CCND1, STEAP4, ARL6, RNASEL, TRIM32, BBS4, OSBPL11, OSBPL8, HMGA2, PID1, CBY1, NR4A2, SMAD6, LRRC8C, EP300, NIPBL, ID4, FAM120B, EGR2, ADIG, ATF2, ALOXE3, SREBF1, NR4A3, DYSF, ZBTB7A, NR4A1, AKT2, PRLH, METRNL, GLIS1, TMEM120B, ADGRF5, WNT5B, CEBPD, CLIP3 |
| fat pad development | biological process | DGAT2, ARID5B, BBS4, ARRDC3, UBB |
| fatty acid alpha-oxidation | biological process | HACL1, ALDH3A2, ILVBL, PHYH, PEX13, SLC25A17, SLC27A2, HAO1, PECR |
| fatty acid beta-oxidation | biological process | HSD17B4, LEP, DECR1, PEX7, ACADM, PEX2, SCP2, ECH1, HADH, ACAD11, ECHS1, PPARD, ECHDC2, CPT1A, ACAA1, ACAA2, AUH, ADIPOQ, HADHB, ACAD10, MCAT, ECI2, ABCD2, ACOX3, HADHA, ACADVL, BDH2, SLC25A17, CPT2, ACADL, ECHDC1, SLC27A2, ACADS, ECI1, SESN2, CPT1C, ABCD1, CPT1B, ACOX2, ACOX1, ACOXL |
| fatty acid beta-oxidation using acyl-CoA dehydrogenase | biological process | ACADM, ETFDH, ACAD11, IVD, GCDH, ETFB, ACADVL, ACADL, ETFA, ACADS |
| fatty acid beta-oxidation using acyl-CoA oxidase | biological process | HSD17B4, SCP2, AMACR, ACAA1, ECI2, ACOX3, CRAT, ABCD1, DECR2, ACOX2, ACOX1, ACOXL |
| fatty acid biosynthetic process | biological process | PTGS1, PTGS2, BRCA1, PTGDS, SCD, MLYCD, PTGES3, HACD1, ACLY, LPL, OLAH, PRKAB1, XBP1, ELOVL6, PRKAG2, ACSL3, CBR4, ELOVL4, HSD17B8, MCAT, PRXL2B, LIPC, HACD2, PTGES2, ELOVL2, ELOVL5, NDUFAB1, DEGS1, FASN, ACSM2A, SCD5, HACD3, TECR, PTGES, PTGIS, FA2H, PLA2G4A, ACSM5, PLA2G1B, PRKAA2, ACSM3, ACACA, HSD17B12, HPGDS, FADS3, FADS1, TBXAS1, ELOVL1, ELOVL3, ACACB, ACSF3, FADS6, ACSM1, MGLL, FADS2, ACOT4, PECR, OXSM |
| fatty acid catabolic process | biological process | LEP, PPARD, ECI2, LPIN1, ACADVL, ACBD5, PLA2G15, LPIN2, HAO2, LPIN3, FAAH |
| fatty acid elongation | biological process | HACD1, ELOVL6, HACD2, HACD3, TECR, ABCD1 |
| fatty acid elongation, monounsaturated fatty acid | biological process | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| fatty acid elongation, polyunsaturated fatty acid | biological process | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| fatty acid elongation, saturated fatty acid | biological process | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| fatty acid homeostasis | biological process | APOE, XBP1, DGAT2, DGAT1, GOT1, NR1H4, GPAM, PRKAA2, INS, POLD1, ABCD1, ENPP7 |
| fatty acid metabolic process | biological process | PTGS1, PTGS2, BRCA1, HSD17B4, C3, DECR1, PTGDS, CREM, SCD, MLYCD, ACADM, AACS, PNPLA8, NDUFS6, CYP2J2, ECH1, PTGES3, HACL1, HACD1, CYP4A11, CYP4F3, HADH, ACAD11, LPL, ABHD5, ADIPOR1, UGT1A8, OLAH, AMACR, PRKAB1, ECHS1, PPARD, ECHDC2, LYPLA1, IVD, CPT1A, ALKBH7, ELOVL6, PRKAG2, GNPAT, ACSL3, ACSL1, ALDH3A2, UCP3, ACSBG2, SLC27A3, CBR4, ELOVL4, ILVBL, PHYH, ACAA1, ACAA2, BAAT, THEM5, HSD17B8, SLC27A5, FABP3, HADHB, MCAT, PRXL2B, CRYL1, HPGD, CYP4F8, LPIN1, MSMO1, SLC27A1, ADIPOR2, PER2, ACOX3, AASDH, HACD2, PTGES2, ANGPTL3, CYP2C19, ECHDC3, ELOVL2, ELOVL5, NDUFAB1, DEGS1, HADHA, FASN, ACSM2A, SCD5, HACD3, CRAT, ACADVL, TECR, ACSL5, PTGES, CPT2, ACADL, THEM4, PTGIS, FA2H, ACOT7, ACSL4, ACADSB, PLA2G4A, ACSM5, PLA2G15, GPAM, PRKAA2, LPIN2, SLC27A2, NAAA, ACSM3, ALOXE3, CYP4F12, TMEM189, ACOT2, ACACA, TH, PRKAR2B, PLA2G5, HPGDS, ACOT11, FADS3, FADS1, CYP2E1, ACADS, TBXAS1, ECI1, CYP4F2, ELOVL1, GGT1, AOAH, SLC27A4, CPT1C, ELOVL3, ACACB, ALOX12B, CYP2D6, PPARA, ACSF3, FADS6, CPT1B, ACSBG1, CYP2S1, DECR2, ABCB11, AC |
| fatty acid omega-oxidation | biological process | ADH4, ADH5 |
| fatty acid oxidation | biological process | PPARG, MAPK14, MLYCD, ADIPOR1, PPARD, PPARGC1A, POR, ADIPOQ, ADIPOR2, GCDH, HAO2, ACSM1, CYGB, ACOX1 |
| fatty acid primary amide biosynthetic process | biological process | PAM |
| fatty acid transport | biological process | PPARD, ACSL1, SLC27A5, SLC27A1, SLC25A17, MFSD2A, ACSL4, SLC27A2, GOT2, SLC27A4, PPARA |
| fatty-acyl-CoA biosynthetic process | biological process | SCD, PPT1, ACLY, CBR4, HSD17B8, SLC25A1, GCDH, FASN, SCD5, ACACA |
| fatty-acyl-CoA transport | biological process | ABCD1 |
| Fc receptor mediated inhibitory signaling pathway | biological process | LYN |
| Fc receptor mediated stimulatory signaling pathway | biological process | LYN, FCER1G |
| Fc receptor signaling pathway | biological process | KIT, PIGR, CD200R1, FCAR |
| Fc-epsilon receptor signaling pathway | biological process | MAPK3, MAPK1, PIK3CA, MAPK8, SOS1, PSMA3, MALT1, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, PSMD14, BCL10, PIK3R1, SHC1, PSMD7, BTRC, MAP3K7, PSMB6, VAV3, PSMD10, PSMD8, PSMC5, NFATC1, PPP3CB, PSMB4, SYK, PSME1, CUL1, GRAP2, PSMB8, PSMD4, TAB1, LAT2, PSMC3, PSMA6, ITK, NFATC3, FCER1A, RELA, PRKCQ, MAP2K4, NFATC2, MAP2K7, TEC, LILRA4, GAB2, CALM1, IKBKG, TAB2, PSMD12, PSMB9, PSMC4, MAPK9, GRB2, RAC1, PPP3CA, PSMD9, FER, PSMA4, VAV2, PSMD2, TRAF6, LYN, PSMD5, TAB3, PSMF1, FOS, PSMB3, BTK, LCP2, IKBKB, PSMD3, FCER1G, PSMC1, PPP3R1, LAT, PIK3R2, VAV1, PDPK1, CARD11, PLCG2, MAPK10, MS4A2, MAP3K1, PSMD13, PSMB10 |
| Fc-gamma receptor signaling pathway | biological process | FCER1G, CLEC4D |
| Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | HSP90AA1, MAPK3, MAPK1, YES1, SRC, PIK3CA, FCGR3A, ACTB, CDC42, PLA2G6, WIPF3, WASL, ARPC1A, ACTR3, BAIAP2, ARPC3, NCKAP1, PIK3R1, NCK1, VAV3, ARPC5, WIPF1, PTK2, SYK, FCGR2B, CYFIP2, CD3G, CD247, GRB2, RAC1, ELMO2, WASF2, ABL1, VAV2, ACTG1, CYFIP1, ABI1, LYN, PRKCD, DOCK1, ACTR2, MYO10, PRKCE, FGR, PLD2, FCGR2A, NCKAP1L, WIPF2, HCK, WAS, MYO1C, CRK, ARPC4, PIK3R2, ARPC1B, VAV1, NCKIPSD, LIMK1, MYO1G, PLCG2, PLPP4, ELMO1, MYH2 |
| fear response | biological process | ADRB1, DBH, DRD4 |
| feeding behavior | biological process | PRLHR, MRAP2, HCRTR1, NPY, NEGR1, NTRK2, PMCH, UCN, MCHR1, NPY1R, NMUR2, CALCA, HTR2C, NPB, DRD1, HTR1B, HCRT, GIGYF2, GAL, DRD2, PRLH, GALR3, STRA6, PYY |
| female courtship behavior | biological process | THRB, THRA |
| female gamete generation | biological process | FSHB, FSHR, ATM, SPO11, MSH4, GDF9, BMP15, DYNLL1, DMC1, M1AP, MCM8, DIAPH2, PARN, MCM9, USP9X, HROB, BCL2L10, TOB2, CGB3 |
| female genitalia development | biological process | SRD5A2, SRD5A1, CHD7, TBX3, STRA6 |
| female genitalia morphogenesis | biological process | TP63, RBP4, FGF10 |
| female gonad development | biological process | FSHR, BRCA2, NR5A1, AMHR2, ESR2, IDH1, FANCA, NUP107, SMAD4, COL9A3, PLEKHA1, WNT4, ARID5B, TIPARP, CCDC182, PDGFRA, UBB, FOXL2 |
| female gonad morphogenesis | biological process | SMAD4 |
| female mating behavior | biological process | FUOM |
| female meiosis chromosome segregation | biological process | MLH1, PLK1, TTK |
| female meiosis chromosome separation | biological process | NCAPH2, NCAPH |
| female meiosis I | biological process | MLH3, MEIOB, TRIP13, MEIOC, UBB, CDC25B |
| female meiosis II | biological process | DAZL, MASTL |
| female meiosis sister chromatid cohesion | biological process | STRA8, RAD51C |
| female meiotic division | biological process | HSF1, NCAPH2, NCAPH, EREG, SYCP2, MARF1, PPP2R1A |
| female pregnancy | biological process | GNAS, TGFB1, FSHB, IL4, BCL2, TGFB3, ADM, IGF2, GNRH1, PRL, LEP, PGF, HFE, IGF1, TAC3, COMT, OXTR, OXT, DDR1, GC, PSG1, SLC19A1, CD38, SPHK2, LGALS9, CAPN2, STAT5B, KRAS, THBD, IDO1, FOSB, RAMP2, RLN2, PRLHR, GHSR, MAGED2, CRH, HPGD, NAMPT, ADIPOR2, CRHBP, SLC38A2, ETS1, ITGA2, UCN, UPRT, CLIC5, LNPEP, EPN1, FOS, CRHR1, DHODH, IGFBP2, ADRA2B, PTHLH, UMPS, PSG9, PSG5, OVGP1, GOT2, ADRA2C, IGFBP5, COL16A1, CLDN4, AMBP, HSD11B2, PSG6, CAD, TEAD3, SLC38A3, AGT, RLN1, PSG7, STS, RARA |
| female sex determination | biological process | WNT4 |
| female somatic sex determination | biological process | FOXL2 |
| ferrous iron import into cell | biological process | TF |
| fertilization | biological process | BAX, APOB, REC8, TEX11, TEX15, INSL6, NR2F2, STRA8, SPACA3, SPATA22, TDRD9, MAEL, KLHL10, MEIOB, YBX3, TDRKH, IFTAP, LYZL6, UBE2Q1, CLIC4, ATP1A4, RIMBP3B, PCSK4, ACRBP, TDRD12, BCL2L1, SYCP2, AAAS, ASTL, SPTBN4, TEX101, FNDC3A |
| fertilization, exchange of chromosomal proteins | biological process | TNP1 |
| fever generation | biological process | IL1B, IL1A, TRPV1 |
| fibrinolysis | biological process | SERPINE1, KRT1, PLAUR, PLAU, PLAT, ANXA2, FGG, SERPINB2, PROS1, SERPINF2, F12, FGB, PLG, FGA, HRG, SERPING1, GP1BA, F2 |
| fibroblast activation | biological process | IL17A, ULK3, RGCC, IL17RA |
| fibroblast apoptotic process | biological process | BAK1, MYC |
| fibroblast growth factor receptor apoptotic signaling pathway | biological process | FGFR3 |
| fibroblast growth factor receptor signaling pathway | biological process | ANOS1, FGFR2, FGFR3, MAPK3, MAPK1, FGFR1, FGF17, FGF8, PTPN11, FLRT3, FGF3, FGF9, RBFOX2, CCN2, HNRNPF, FGF12, CEP57, HNRNPM, NCBP2, POLR2F, HNRNPA1, IQGAP1, POLR2G, FLRT1, GTF2F1, ESRP1, TIA1, SETX, SHOC2, NCBP1, SPRED1, POLR2B, POLR2D, FGF23, FLRT2, TIAL1, KIF16B, FGF5, RAB14, POLR2J, POLR2L, POLR2E, NDST1, FGF20, HNRNPH1, GRB2, SHCBP1, CBL, POLR2K, FIBP, POLR2I, FRS2, GTF2F2, TRIM71, FGF18, ESRP2, FGF22, POLR2C, FGF7, FRS3, FGF19, FGF6, FGFBP1, FGF21, FGF2, POLR2H, KL, FGFR4, POLR2A, FGF1, FGF14, CRKL, FGF10 |
| fibroblast growth factor receptor signaling pathway involved in hemopoiesis | biological process | FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in mammary gland specification | biological process | FGFR2, FGF10 |
| fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow | biological process | FGFR2 |
| fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development | biological process | FGFR2, FGFR1 |
| fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow | biological process | FGFR2 |
| fibroblast migration | biological process | IQGAP1, ZFAND5, PDLIM1, ARID5B, PIP5K1A, PML, CCN3, ILK, TNS1, TMEM201 |
| fibroblast proliferation | biological process | EDNRA, WNT7B, AGT |
| fibronectin fibril organization | biological process | LOXL3 |
| fibrous ring of heart morphogenesis | biological process | BMPR1A |
| filopodium assembly | biological process | ITGA6, EZR, CDC42, PPP1R9B, ARHGEF4, DNM3, SRGAP2, FGD6, SPATA13, S1PR2, FGD4, FGD2, TTYH1, RAB17, FGD5 |
| flagellated sperm motility | biological process | CATSPER1, CATSPER2, APOB, TNP1, AKAP4, PGK2, DDX4, INSL6, GAPDHS, LDHC, NME8, NPHP4, CATSPER4, CATSPER3, SLC26A8, TEKT3, DNAH1, TEKT2, DNAH5, DNAH11, DNAI1, CFAP65, LRRC6, TTC21A, QRICH2, DPCD, CCNYL1, SORD, NEURL1, TTLL1, SLC9C1, ING2, ATP1A4, ROPN1B, SLC9B2, SLC22A16, CATSPERD, TTLL9, ASH1L, CACNA1I, INPP5B, GAS8, CCDC40, TEX101 |
| flavone metabolic process | biological process | UGT1A8, PPARGC1A, UGT1A9, UGT1A7, UGT1A10 |
| flavonoid glucuronidation | biological process | UGT1A8, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| flavonoid metabolic process | biological process | CYP1A1, SULT1A1, POR, SULT1B1, SULT1A3 |
| floor plate development | biological process | COBL, DZIP1L, FOXB1, CHRD, STIL |
| floor plate formation | biological process | GLI2 |
| floor plate morphogenesis | biological process | NODAL |
| fluid transport | biological process | SLC4A11 |
| fluorene metabolic process | biological process | CYP4B1 |
| FMN biosynthetic process | biological process | RFK |
| focal adhesion assembly | biological process | BCL2, SORBS1, FERMT2, ARHGEF7, PEAK1, DLC1, BCR, CTTN, AJUBA, TAOK2, RHOD, RCC2, PIP5K1A, ACTN2, ITGA2, ACTN1, ARHGAP6, ACTN3, CORO2B, THY1, TESK2, PDPK1, PTK2B, TRIP6 |
| folate import across plasma membrane | biological process | LRP2, FOLR1 |
| folate import into mitochondrion | biological process | SLC25A32 |
| folic acid catabolic process | biological process | MTHFS, PM20D2 |
| folic acid metabolic process | biological process | MTHFD1, MTHFR, MTRR, SLC19A1, MTHFD2, SHMT1, DHFR2, MTHFD1L, MTHFS, SHMT2, DHFR, MTHFD2L, ALDH1L1, SLC25A32, FPGS, ALDH1L2, FOLR1 |
| folic acid transport | biological process | SLC19A1, SLC19A2, PDPN, FOLR3, SLC25A32, FOLR1 |
| folic acid-containing compound biosynthetic process | biological process | MTHFD1, MTHFS, FPGS |
| folic acid-containing compound metabolic process | biological process | MTHFD1L, FTCD, FOLH1, FPGS |
| follicle-stimulating hormone secretion | biological process | TBX3 |
| follicle-stimulating hormone signaling pathway | biological process | FSHB, FSHR, ARRB2 |
| follicular B cell differentiation | biological process | FCGR2B, PLCG2 |
| follicular dendritic cell activation | biological process | FCGR2B |
| follicular dendritic cell differentiation | biological process | BCL3, NFKB2 |
| foramen ovale closure | biological process | TBX20, GJA5 |
| forebrain anterior/posterior pattern specification | biological process | SIX3 |
| forebrain astrocyte development | biological process | KRAS, NF1 |
| forebrain cell migration | biological process | AXL, EMX2, TYRO3 |
| forebrain development | biological process | E2F1, APP, GNAO1, CTNNB1, BMP4, SRC, NR2F2, OTX1, SOX2, SHH, ALDH1A2, DYNC2H1, GLI3, NUMBL, ATRX, NUMB, DLC1, HTRA2, ARHGAP35, PPARGC1A, NFIB, CCKAR, NOTCH1, ITGAM, MSX1, DRAXIN, DKK1, PSEN1, EMX2, TTC21B, CNP, NDST1, LRP2, TYROBP, FOXG1, PRKG1, TWSG1, FOXP2, TOP2B, FRS2, ARID1A, DCLK1, DNAJB1, NOTCH3, GSC, CHRD, VAX2, SRF, SSTR4, STIL, HESX1, SSTR3, CDK5, ARX, NDE1, DRD2, MYO1D, RELN, NKX2-1 |
| forebrain dorsal/ventral pattern formation | biological process | FGF8, GLI3, TTC21B, SIX3, NKX2-1 |
| forebrain morphogenesis | biological process | PTEN, FGF8, SLIT1, SMO, HESX1, GDF7, NF1 |
| forebrain neuroblast division | biological process | ASPM, LEF1 |
| forebrain neuron development | biological process | FGF8, RAPGEF2, GBX2 |
| forebrain neuron differentiation | biological process | ASCL1, OTP, LHX5, DLX1, CSF1R, DLX2, NKX2-1 |
| forebrain neuron fate commitment | biological process | NKX2-1 |
| forebrain radial glial cell differentiation | biological process | GLI3, HES1, LEF1 |
| forebrain regionalization | biological process | WNT7B, PGAP1, WNT2B, LHX1 |
| forebrain ventricular zone progenitor cell division | biological process | POU3F3, POU3F2, DIXDC1 |
| foregut morphogenesis | biological process | NOTCH1 |
| forelimb morphogenesis | biological process | NIPBL, TBX5, SALL3, RNF165, HOXD10, TBX3, ZBTB16, FMN1, GDF5 |
| formaldehyde catabolic process | biological process | ADH4, ADH5, ESD |
| formate metabolic process | biological process | MTHFD1L, MTHFS |
| formate transport | biological process | SLC26A6 |
| formation of anatomical boundary | biological process | NODAL, SHH, SMAD4, GDF3 |
| formation of cytoplasmic translation initiation complex | biological process | EIF3H, EIF3E, EIF3D, EIF3K, EIF3L, EIF3F, EIF2S2, EIF3M, EIF3G, EIF3J, EIF3A, EIF3B, EIF5, EIF3C, EIF3I |
| formation of primary germ layer | biological process | KIF16B, ARID1A |
| formation of radial glial scaffolds | biological process | ITGB1, ARL13B, LEF1 |
| formation of translation preinitiation complex | biological process | DENR, EIF2D, MCTS1, EIF2S2, EIF2S3, EIF5, DHX29 |
| formin-nucleated actin cable assembly | biological process | SPIRE1, SPIRE2, FMN2 |
| fourth ventricle development | biological process | MYH10 |
| fractalkine production | biological process | AZU1, TNF |
| free ubiquitin chain polymerization | biological process | PRKN, RNF135, UBE2K, UBE2C, UBE2S, TRIM6 |
| frontal suture morphogenesis | biological process | TGFB1, TGFB3, GLI3, MSX2 |
| fructosamine metabolic process | biological process | MDP1, FN3K |
| fructose 1,6-bisphosphate metabolic process | biological process | PFKM, PFKP, FBP1, ALDOB, ALDOA, FBP2, TIGAR, ALDOC, PFKL |
| fructose 2,6-bisphosphate metabolic process | biological process | PFKFB2, PFKFB4, TIGAR |
| fructose 6-phosphate metabolic process | biological process | PFKM, PFKP, GFPT1, FBP1, TALDO1, HK2, FBP2, NFE2L1, PFKL, HK3 |
| fructose biosynthetic process | biological process | AKR1B1, SORD |
| fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate | biological process | TKFC, GLYCTK, KHK, ALDOB, ALDH1A1 |
| fructose import across plasma membrane | biological process | SLC2A5 |
| fructose metabolic process | biological process | FBP1, KHK, PFKFB2, ALDOB, ALDOA, FBP2, PFKFB4, ALDOC |
| fructose transmembrane transport | biological process | SLC2A5, SLC26A5, SLC2A8, SLC2A6, SLC2A7 |
| fructoselysine metabolic process | biological process | FN3K |
| fucose metabolic process | biological process | FUCA1, B3GLCT, FUOM, POFUT2, FUCA2, POFUT1 |
| fucose transmembrane transport | biological process | SLC5A1 |
| fucosylation | biological process | FUT4, FUT6, FUOM, FUT5, POFUT2, FUT9, FUT7, FUT3, FUT2 |
| fumarate metabolic process | biological process | FH |
| fungiform papilla development | biological process | WNT10B |
| fungiform papilla formation | biological process | CTNNB1, HDAC2 |
| fungiform papilla morphogenesis | biological process | SIX1, SIX4 |
| fusion of sperm to egg plasma membrane | biological process | CATSPER1, SERPINA5, IZUMO1, CD9, SPAM1, CRISP1, LYZL6, ROPN1B, ADAM2, EQTN |
| fusion of virus membrane with host endosome membrane | biological process | env |
| fusion of virus membrane with host plasma membrane | biological process | GAS6, CCR5, env, CXCR4, HYAL2, CD4, PPIA |
| G protein-coupled acetylcholine receptor signaling pathway | biological process | GNAI2, GNB1, GRK2, CHRM3, CDK5R1, RGS10, GNA11, GNAQ, CHRM4, CHRM1, CHRM5, AGRN, RGS8, CHRM2 |
| G protein-coupled adenosine receptor signaling pathway | biological process | GNAI2, P2RY12, ADORA3, P2RY1, ADCY5, ADORA2B, ADORA2A |
| G protein-coupled glutamate receptor signaling pathway | biological process | GRM3, GRM4, GRM8, HOMER2, GRIK3, HOMER1, GRM2, GRM6, DAGLB, TRPM1, HOMER3, DAGLA, GRM5, GRM7, GRM1 |
| G protein-coupled purinergic nucleotide receptor signaling pathway | biological process | P2RY4, P2RY11, GPR171, GPR34, P2RY12, P2RY1, P2RY14, PTAFR, P2RY2, P2RY6 |
| G protein-coupled receptor catabolic process | biological process | GPRASP1 |
| G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger | biological process | AGT |
| G protein-coupled receptor signaling pathway involved in heart process | biological process | RAMP3 |
| G protein-coupled serotonin receptor signaling pathway | biological process | HRH1, HTR7, CHRM3, HRH4, OR10H1, HRH3, CHRM4, CHRM1, CHRM5, HRH2, OR10H2, CHRM2, HTR6, DRD4, HTR2B, OR5T2 |
| G-protein coupled receptor internalization | biological process | ADM, GRK4, SAG, CALCA, DRD3, HTR1B, DNM1, DRD2, ARRB2, HTR2B |
| G-protein coupled receptor signaling pathway | biological process | APOE, CXCL8, LHCGR, FSHR, GNAS, RXFP2, AKT1, GHRL, C3, GNAO1, EDNRA, GNRHR, AKR1C3, GNAI1, INSR, IGF2R, CCL5, FPR1, IL2, GPRC6A, PROKR2, KISS1R, F2R, TACR3, OXTR, PPARG, CCR5, TAS2R38, OR2W3, PROK2, MAS1, CX3CL1, CCL16, IAPP, AREG, P2RY4, OR12D2, CCL20, PDE4C, VN1R2, LPAR4, ACKR4, GPR160, OR2AG2, LANCL1, JAK2, GRK5, CXCR4, GPSM2, AKAP12, GRM3, GRM4, F2RL3, ARHGEF3, FZD9, KALRN, CCR1, GPR183, CCL8, OR10AD1, OR5AR1, OR52D1, HEBP1, OR5V1, TULP3, ADGRL1, KCNK2, UTS2, GNAI2, GNB3, PIK3R1, BDKRB2, ARHGEF7, OR9A4, OR51A7, P2RY11, ADGRA2, LGR4, FZD8, GPR83, TAS2R9, RGS17, FZD4, CYSLTR1, RAPGEF2, CXCL11, GPR171, ARHGEF11, GPR37L1, CCL1, OR1G1, PTH1R, CALCRL, CCL14, OR9Q2, OR51V1, RAPGEFL1, VAV3, GNB5, GIPC1, RGS16, GNG7, CCL3, PRKACB, HRH1, XCR1, TAS2R19, MC2R, PDE7A, PREX2, TAS1R2, CXCL16, OR52A1, GPR45, ROCK2, RGS20, ANXA1, GNAI3, MCF2, LPAR6, CCL11, AKR1C2, PDE1A, GNB1, QRFP, ABR, ARHGEF6, OPN5, OR1L6, GPR119, PTH2, HCAR1, GNB4, RXFP1, ZNF219, GRM8, ARHGEF9, RAMP2, C5, RLN2, GRP, GNAZ, PTPN6, CCKAR, PRLHR, TAS2R50, |
| G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | biological process | LHCGR, CCR1, PTH1R, CALCRL, HRH1, XCR1, MC2R, ANXA1, NPY, HTR7, ADRB3, MTNR1A, CHRM3, CNR1, HTR1E, OPRD1, HRH4, NPY1R, HTR2C, OR10H1, DRD1, HTR1B, SSTR4, LPAR3, HRH3, TSHR, SSTR3, PTGIR, CHRM4, CHRM1, CHRM5, HRH2, HTR5A, OR10H2, GALR3, SSTR5, CHRM2, HTR6, DRD4, MC1R, CCL2, HTR2B, MC3R, OR5T2 |
| G-quadruplex DNA unwinding | biological process | DHX36, HNRNPA2B1, BLM, DDX11 |
| G0 to G1 transition | biological process | CDK3 |
| G1 DNA damage checkpoint | biological process | WAC |
| G1 to G0 transition | biological process | EZH2, SMPD3, RIDA, CYP27B1, PHGDH, ECRG4 |
| G1 to G0 transition involved in cell differentiation | biological process | ZNF503, CAPN3, SLC39A5 |
| G1/S transition of mitotic cell cycle | biological process | INHBA, CDK1, CDC25A, CDKN2A, ITGB1, RB1, CDC7, PCNA, CCNA1, MCM3, NASP, CDKN3, RBBP8, MCM8, ORC5, PIAS1, GSPT1, PRIM2, MAX, CACUL1, PLK2, DBF4, RPA2, CDK7, ACVR1B, CCNH, RHOU, POLE3, RPS6KB1, PPP6C, ZNF324, ACVR1, IQGAP3, USP29, RPA1, CUL1, ORC1, USP37, CCND1, ORC3, E2F3, CDC45, BCAT1, ORC2, CRLF3, CDKN2D, EIF4EBP1, CDC6, GPR132, CUL5, LATS2, EIF4E, CCNE1, CDK6, SKP2, PHF8, MCM5, CDKN1B, ID4, PPP3CA, CUL2, ORC4, CDKN2C, SPDYA, LATS1, RPA3, CDC34, TAF10, TRIM71, RCC1, CDKN1A, CDK3, POLE4, MCM4, MCM7, PRIM1, PPAT, POLE, POLA2, MCM6, MNAT1, PLK3, CCNE2, HINFP, PIM2, MCM10, MCM2, CAMK2A, POLA1 |
| G2 DNA damage checkpoint | biological process | BRCA1 |
| G2/M transition of mitotic cell cycle | biological process | BIRC5, CCNB2, CDK1, HSP90AA1, ABCB1, CCNB1, WEE1, CDC25A, CDC25C, ODF2, BRSK2, KHDRBS1, TUBA4A, DYNLL1, FOXM1, DYNC1H1, OFD1, PCM1, BORA, CEP57, OPTN, HAUS2, CETN2, CEP70, PPP1R12A, CCP110, CDK7, SKP1, NEDD1, CDK14, CCNH, PPP2R2A, FBXL22, CCNY, CEP41, HAUS4, FBXL12, BTRC, CSNK1E, DYNC1I2, MASTL, CDK5RAP2, DCTN3, HAUS5, CUL1, AJUBA, CEP131, PPME1, CEP43, ARPP19, PPP1CB, USH1C, CDKN2B, CSNK1D, SDCCAG8, MELK, TUBB, CALM3, PLK1, FBXL3, YWHAE, TUBB4B, SKP2, AKAP9, LCMT1, CEP164, TUBG1, TPD52L1, ALMS1, CEP63, TAF2, HAUS6, LATS1, DCTN2, CNTRL, CEP290, ACTR1A, CKAP5, TUBB4A, CDKN1A, MAPRE1, YWHAG, CEP250, SFI1, PCNT, PRKAR2B, PKMYT1, WNT10B, PPP1R12B, MNAT1, PLK3, KDM8, NDE1, KAT14, PPP2R1A, FBXL7, NINL, CDC25B, CLASP1, BRSK1, CEP192, CEP72, SSNA1, NES, NEK2, PHLDA1 |
| GABAergic neuron differentiation | biological process | INHBA, GATA2 |
| galactitol metabolic process | biological process | GALK1 |
| galactolipid catabolic process | biological process | PNLIPRP2 |
| galactose catabolic process | biological process | GLB1, GALT, PGM2L1, PGM1, GALE, PGM2, GALK1 |
| galactose catabolic process via UDP-galactose | biological process | GALT, GALE, GALM |
| galactose metabolic process | biological process | GALT, PPARGC1A, GALE, GALK2, GALM, B4GALT1, GALK1, SLC35A2 |
| galactose transmembrane transport | biological process | SLC2A10, SLC5A1 |
| galactosylceramide biosynthetic process | biological process | B3GALT2, B4GALT3, B3GALT1, FA2H, UGT8 |
| galactosylceramide catabolic process | biological process | PSAP, GALC |
| galanin-activated signaling pathway | biological process | GALR3 |
| gall bladder development | biological process | NIPBL |
| gamete generation | biological process | MEI1, SPATA22, DMC1, DDX3X, FANCD2, MCM9, WNT4, FANCL, FANCC, SPIN2A, CTDNEP1, ZNF148, WNT3, DDX3Y |
| gamma-aminobutyric acid biosynthetic process | biological process | SLC1A3, GAD1, ABAT |
| gamma-aminobutyric acid catabolic process | biological process | ABAT, ALDH5A1 |
| gamma-aminobutyric acid import | biological process | SLC6A6, SLC9A3R1 |
| gamma-aminobutyric acid metabolic process | biological process | PHGDH, ABAT, ALDH5A1 |
| gamma-aminobutyric acid receptor clustering | biological process | NRXN1, LHFPL4, GPHN, SHISA7 |
| gamma-aminobutyric acid secretion | biological process | APBA1, TRPC4 |
| gamma-aminobutyric acid secretion, neurotransmission | biological process | NF1 |
| gamma-aminobutyric acid signaling pathway | biological process | GABRB1, SLC12A2, GNAI2, GABRA2, PLCL1, GABRG2, GABRB3, ATF4, GABRA5, GABRB2, GABRA4, GABRG1, GABBR1, GABRR2, GABRA1, GPR156, GABRA3, SHISA7, GABRR3, GABRG3, PLCL2 |
| gamma-aminobutyric acid transport | biological process | SLC6A11, SLC6A12, SLC32A1, SLC6A13 |
| gamma-delta T cell activation | biological process | ITK, MICB, CXADR, JAML |
| gamma-delta T cell differentiation | biological process | JAG2 |
| gamma-tubulin complex localization | biological process | MZT1, CEP72 |
| ganglion development | biological process | TULP3 |
| ganglion mother cell fate determination | biological process | NTF4 |
| ganglioside biosynthetic process | biological process | ST6GALNAC6, B4GALNT1, ST6GALNAC4, ST8SIA2, ST8SIA4, ST6GALNAC5, ST6GALNAC3, ST8SIA3 |
| ganglioside biosynthetic process via lactosylceramide | biological process | B4GALT6, B4GALT5 |
| ganglioside catabolic process | biological process | HEXB, NEU1, NEU4, NEU2, GM2A |
| ganglioside GM1 transport to membrane | biological process | PSAP |
| ganglioside metabolic process | biological process | ITGB8, CLN6, GM2A |
| gap junction assembly | biological process | GJA1, CTNNA1, GJB1, GJA5, GJB6, GJD3, GJC1 |
| gap junction-mediated intercellular transport | biological process | GJA3, GJB6, GJB4 |
| gastric acid secretion | biological process | GHRL, SNX10, NMU, SLC26A7, CHRM5, HRH2 |
| gastric emptying | biological process | UCN, DRD3 |
| gastric inhibitory peptide signaling pathway | biological process | GIPR |
| gastrin-induced gastric acid secretion | biological process | HRH2 |
| gastrulation | biological process | NODAL, FGF8, EXT1, TXNRD1, SMAD4, CER1, EOMES, RACK1, ACVR1, SUPT20H, HIRA, SYF2, WNT8B, MIXL1, CFC1B, ARID1A, SMAD2, GSC, POGLUT1, SRF, TGFBR2, APLNR, CRB2, ARFRP1, NR4A3, MESP1, RIC8A, SMAD3, TP53 |
| gastrulation with mouth forming second | biological process | NODAL, CTNNB1, SMAD4, ACVR1, UGDH, ACVR2B, AMOT, LRP6, LHX1, FRS2, ACVR2A, LRP5, CHRD, ZBTB17, TENM4, LRP5L, RNF2 |
| GDP biosynthetic process | biological process | GUK1 |
| GDP metabolic process | biological process | DLG1, CASK, MPP1, LRGUK, MAGI3, CARD11, DLG2 |
| GDP phosphorylation | biological process | AK9 |
| GDP-fucose import into Golgi lumen | biological process | SLC35C1 |
| GDP-fucose transmembrane transport | biological process | TMEM241 |
| GDP-L-fucose metabolic process | biological process | FUT8 |
| GDP-L-fucose salvage | biological process | FCSK |
| GDP-mannose biosynthetic process | biological process | MPI, PMM1, GMPPB |
| GDP-mannose metabolic process | biological process | GUK1, GMDS, TSTA3 |
| gene expression | biological process | FAS, HNRNPL, RBMX, HOXA3, FUS, LTB, ADIPOQ, PSAP, NR4A2, TAF15, YY1, KBTBD2, GOLPH3, EGR2, ANGPT2, CRB1, P2RX7, EDA, LAT, TCIRG1, MESP1, ZBTB25, FMN1, RNF2 |
| gene silencing | biological process | DNMT1, SRCAP, CHMP1A, SOX6, SCMH1, KMT2B |
| gene silencing by miRNA | biological process | CNOT1, CNOT8, AJUBA, WTIP, TNRC6B, TNRC6A, TNRC6C, EIF6, MOV10, LIMD1 |
| gene silencing by RNA | biological process | PIWIL2, PIWIL1, PABPC1, LIN28B, DDX4, DROSHA, DICER1, PIWIL4, TDRD9, MAEL, FKBP6, HIST1H4A, PIWIL3, FAM172A, NCBP2, TDRKH, CNOT1, AGO4, CNOT8, SNIP1, PRKRA, ADAR, NCBP1, HENMT1, TARBP2, AJUBA, AGO3, CNOT10, EXD1, ERI1, CNOT9, SRRT, TDRD12, RBM4, AGO2, WTIP, CNOT6L, CNOT2, TNRC6B, ZFP36, TRIM71, TNRC6A, DDX17, TNRC6C, MOV10, AGO1, TUT4, LIMD1, CNOT3, SND1, TDRD1, LIN28A |
| general adaptation syndrome | biological process | NR4A2 |
| general adaptation syndrome, behavioral process | biological process | PENK |
| generation of catalytic spliceosome for first transesterification step | biological process | XAB2, PRPF19 |
| generation of catalytic spliceosome for second transesterification step | biological process | PRPF18, ISY1 |
| generation of neurons | biological process | FGFR1, FGF8, CIT, ASCL1, TGFB2, CDK6, THOC2, SIX1, SIX4, PTF1A |
| generation of ovulation cycle rhythm | biological process | KISS1, NPY5R |
| generation of precursor metabolites and energy | biological process | AQP7, COX17, ATP5F1B, SLC25A4, COX7C, PHKB, FECH, PPP1R2, GYS2, OGDH, ASIP, PPARD, GBE1, ADIPOQ, ACO2, COX6A1, COX6C, ADRB3, ENPP1, GNPDA1, GIPR, PDX1, ATP5IF1, GCGR, MCHR1, UQCR11, PHKG2, COX8A, COX4I1, CYB5R4, PHKA2, AVP, XYLB, VGF, COX6A2, COX7A1, TREX1, POMC, DHTKD1, THTPA, DLST, ACOX1 |
| genetic imprinting | biological process | GNAS, NDN, ASIP |
| genitalia development | biological process | HNF1B, PTPN11, CHD7, PKD1, NEUROG1, DNAJC19, TIFAB, FOXF2 |
| genitalia morphogenesis | biological process | CTNNB1, NEUROG1, TIFAB |
| gentamycin metabolic process | biological process | SLC34A1 |
| gephyrin clustering involved in postsynaptic density assembly | biological process | NRXN1, NLGN2, NRXN2 |
| germ cell development | biological process | WT1, BAX, ERCC1, AKT1, MTOR, DAZL, BMP4, MOV10L1, MSH2, NANOS3, DZIP1, ACVR1, PRDM1, TIAL1, DEAF1, CELF4, ANGPT2, FANCC, BCL2L1, RNF2, SMAD5, RARA, TDRD1, LIN28A |
| germ cell migration | biological process | TGFB1, DMRT1, ITGB1, KIT, CXADR, TGFBR1, FOXC1 |
| germ-line stem cell population maintenance | biological process | PIWIL2, NANOS2 |
| germinal center B cell differentiation | biological process | CDH17, ADA, ITFG2, POU2AF1 |
| germinal center formation | biological process | BCL6, BCL3, MEF2C, KLHL6, NFKB2, UNC13D |
| germline cell cycle switching, mitotic to meiotic cell cycle | biological process | OVOL1, MEIOC |
| ghrelin secretion | biological process | GHSR |
| gland development | biological process | PROP1, RARG, HRH2 |
| gland morphogenesis | biological process | BCL2, FGFR2, EZR, HOXD13, SLC9A3R1, NKX2-3, MSN, GDF7 |
| glandular epithelial cell development | biological process | RARB, FASN, RARG, RARA |
| glandular epithelial cell differentiation | biological process | IL31RA |
| glial cell apoptotic process | biological process | BAX, CASP3, CASP9, RB1 |
| glial cell development | biological process | PICK1, SOX11, PHGDH, SOX4, LGI4 |
| glial cell differentiation | biological process | NRG1, PHOX2B, NFIB, NOTCH1, DTX1, NEUROD4, FGF5, ASCL1, METRN, CRB1, DNER, RELN, GAP43 |
| glial cell fate commitment | biological process | NRG1, SOX2, NFE2L1 |
| glial cell fate determination | biological process | CTNNB1 |
| glial cell migration | biological process | FN1, NDN, CSPG4, MATN2, P2RY12, TGFB2, EPHA4, P2RY1, AZU1 |
| glial cell projection elongation | biological process | MDK, CSPG5 |
| glial cell proliferation | biological process | AREG, EEF2, SOX11, SOX4, LGI4, PTK2B, PENK |
| glial cell-derived neurotrophic factor receptor signaling pathway | biological process | GFRA1, RET, SULF1, GFRA3, GFRA2, SULF2, GFRA4 |
| gliogenesis | biological process | ANXA1, GCM2, CDK6, ADAM22, LGI4, GCM1 |
| global genome nucleotide-excision repair | biological process | ERCC1, ERCC2, XPA, PARP1, RAD23B, SUMO1, XPC, GTF2H3, CETN2, RPS27A, CHD1L, DDB2, USP45, GTF2H1, RNF111, UBC, UBA52, ERCC4, GTF2H4, RBX1, UBB, DDB1, GTF2H5 |
| globoside biosynthetic process | biological process | A4GALT |
| globus pallidus development | biological process | ARX, KCNC1, KCNC2, NKX2-1 |
| glomerular basement membrane development | biological process | WT1, COL4A3, SULF1, NPHS1, COL4A4, MPV17, SULF2 |
| glomerular capillary formation | biological process | BMP4, NOTCH3 |
| glomerular endothelium development | biological process | CD34, FOXC2, PECAM1 |
| glomerular epithelium development | biological process | FOXC1 |
| glomerular filtration | biological process | EDNRA, CD34, TMEM63C, XPNPEP3, SULF1, SULF2, ADGRF5, MCAM |
| glomerular mesangial cell development | biological process | NOTCH1, GPR4, FOXC2, ACTA2 |
| glomerular mesangial cell proliferation | biological process | EGR1 |
| glomerular parietal epithelial cell development | biological process | FOXJ1 |
| glomerular visceral epithelial cell development | biological process | BMP4, IQGAP1, ASXL1, PODXL, NPHS1, JAG1, MAGI2 |
| glomerular visceral epithelial cell differentiation | biological process | WT1, BASP1, FOXC2, PTPRO |
| glomerular visceral epithelial cell migration | biological process | KANK2, ANLN |
| glomerulus development | biological process | BCL2, WT1, PLCE1, VANGL2, PTPRO, ENPEP, WWTR1 |
| glomerulus morphogenesis | biological process | KIRREL3, MEF2C, MTSS1 |
| glomerulus vasculature development | biological process | HES1, TEK, ANGPT1, ANGPT2 |
| glossopharyngeal nerve development | biological process | NAV2 |
| glossopharyngeal nerve morphogenesis | biological process | HOXA3, HOXD3, PLXNA4, HOXB3 |
| glucagon secretion | biological process | IL6 |
| glucocorticoid biosynthetic process | biological process | CYP17A1, CYP11A1, HSD3B1, CYP11B1, HSD3B2, CYP21A2, CRH, HSD11B1, HSD11B2 |
| glucocorticoid catabolic process | biological process | YWHAH |
| glucocorticoid mediated signaling pathway | biological process | NR3C1 |
| glucocorticoid metabolic process | biological process | STAR, APOA1, MECP2, HSD11B2 |
| glucocorticoid receptor signaling pathway | biological process | NR3C1, YWHAH, NEDD4, ARID1A, CALR |
| gluconeogenesis | biological process | ATF3, GAPDH, ENO1, G6PC3, GAPDHS, PGK1, PGAM1, PGAM4, MDH2, SLC25A13, MDH1, PGM1, PPARGC1A, ENO2, PCK2, FBP1, PC, SLC25A1, PER2, ALDOB, ATF4, ALDOA, PGAM2, GOT1, TPI1, GPI, CRY1, SLC37A4, SLC25A11, ENO3, SLC25A10, FBP2, ALDOC, SLC25A12, GOT2, RBP4, SDS, SLC39A14, G6PC2, GPD2 |
| glucosamine catabolic process | biological process | GNPDA1, GNPDA2 |
| glucosamine metabolic process | biological process | PGM3, GNPNAT1 |
| glucose 1-phosphate metabolic process | biological process | UGP2, PGM3 |
| glucose 6-phosphate metabolic process | biological process | G6PC3, G6PD, HKDC1, GPI, HK2, NFE2L1, GCK, HK3, G6PC2 |
| glucose catabolic process | biological process | BAD, PFKM, TKTL1, PFKP, PFKFB2, LRP5, PFKL |
| glucose homeostasis | biological process | IL6, HIF1A, HNF1A, AKT1, CYP11B1, STAT3, LEP, LEPR, BAD, INSR, PPARG, PTPN11, FOXO1, WFS1, USF1, TCF7L2, RPS6, PDK4, PDK3, SESN3, OAS1, ADIPOR1, FBN1, FAM3B, FABP5, PTPN2, FOXA1, ADIPOQ, PRCP, SELENOT, ADIPOR2, IRS1, PDX1, CAV3, SLC30A8, ADRA2A, GCGR, BACE2, ACSM2A, NEUROD1, CNR1, KCNB1, NR1H4, MBD5, ADCY8, CSRP3, INPP5K, PDK1, CYB5R4, SIDT2, ALOX5, CRY1, SLC37A4, PRKAA2, SOX4, BHLHA15, CCDC186, ERO1B, KLF7, SLC2A4, SIRT6, APPL2, GPR21, PYGL, NMB, HNF4A, RFX6, FFAR1, SLC16A1, FOXO4, VGF, NGFR, SESN2, CSMD1, FOXO3, RBP4, FGFR4, IGFBP5, POMC, INS, DBH, GCK, PTCH1, CRY2, SSTR5, PDK2, SLC8B1, ASPSCR1, RPH3AL, CCN4, ADGRF5, STXBP5L, SUCNR1, RMI1, NCOA5, G6PC2 |
| glucose import | biological process | HNF1A, TSC1, SLC2A10, SLC2A13, SORT1, SLC2A8, SLC2A4, RAB4B, DRD1, SESN2, SLC2A6 |
| glucose import across plasma membrane | biological process | SLC2A3, SLC2A10, SLC5A1, SLC5A2 |
| glucose import in response to insulin stimulus | biological process | SLC2A4, ZDHHC7, TRARG1 |
| glucose mediated signaling pathway | biological process | ADCY8, AGER |
| glucose metabolic process | biological process | TNF, IGF2, AKT1, GHRL, GAPDH, LEP, PIK3CA, GAPDHS, G6PD, USF1, CREM, GAA, MAPK14, DCXR, PDK4, ADPGK, PDK3, SERP1, PDHA1, OAS1, SORD, PGM2L1, FBN1, PPARD, OMA1, AKR1A1, CPT1A, FABP5, PGM1, PKM, ADIPOQ, IRS2, PDX1, APOD, PGM5, PDHB, BRS3, KBTBD2, WDTC1, TPI1, PDK1, GALM, H6PD, SLC37A4, NPY1R, HK2, PGM2, NISCH, BRAT1, ONECUT1, DLAT, INS, AKT2, GCK, PDK2 |
| glucose transmembrane transport | biological process | SLC2A5, SLC2A3, PPARD, MFSD4B, SLC2A10, SLC2A14, SLC2A8, SLC2A11, SLC2A4, SLC5A1, PPBP, SLC5A10, SLC2A6, SLC2A7, MFSD4A, SLC45A1, SLC5A9 |
| glucose transport | biological process | AKT1, EDNRA, G6PC3, GH1, YES1, NRG1 |
| glucose-6-phosphate transport | biological process | G6PC3, SLC17A3, SLC37A3, SLC37A4, SLC37A1, SLC37A2 |
| glucoside transport | biological process | SLC50A1 |
| glucosylceramide biosynthetic process | biological process | FA2H, UGCG |
| glucosylceramide catabolic process | biological process | GBA, GBA2 |
| glucosylceramide metabolic process | biological process | PSAP |
| glucuronate catabolic process to xylulose 5-phosphate | biological process | DCXR, SORD, AKR1A1, CRYL1, XYLB |
| glucuronoside catabolic process | biological process | ABHD10, GUSB |
| glutamate biosynthetic process | biological process | GLUD1, GLUD2, GLS2, SLC25A12, GLS |
| glutamate catabolic process | biological process | GLUD1, GLUD2, GAD1, GLUL |
| glutamate catabolic process to 2-oxoglutarate | biological process | GOT1, GOT2 |
| glutamate catabolic process to aspartate | biological process | GOT1, GOT2 |
| glutamate catabolic process via 2-oxoglutarate | biological process | ADHFE1 |
| glutamate decarboxylation to succinate | biological process | GAD1, GAD2 |
| glutamate homeostasis | biological process | KCTD7, GRM2, GLS |
| glutamate metabolic process | biological process | GLUD2, GCLC, MTHFS, ALDH18A1, GLUL, GOT1, DGLUCY, ALDH5A1, TAT, AADAT, FPGS, GOT2, GGT1 |
| glutamate receptor signaling pathway | biological process | FMR1, KCNB1, GRIN2C, GNAQ, GRIK3, GRIN2B, GRID2, GRIA3, GRIK4, GRIN2A, GRIK1, GRIK2 |
| glutamate reuptake | biological process | KCNJ10 |
| glutamate secretion | biological process | PPFIA1, RIMS1, GIPC1, CPLX1, PPFIA2, SLC1A2, SYT1, SLC1A3, NTRK2, SLC38A2, SNAP25, UNC13B, SLC1A6, APBA1, GRM2, PPFIA3, GLS2, SLC1A7, GLS, PPFIA4, SLC17A7, TRPV1 |
| glutamate secretion, neurotransmission | biological process | NF1 |
| glutamine biosynthetic process | biological process | GLUL |
| glutamine catabolic process | biological process | PPAT, GLS2, GLS |
| glutamine metabolic process | biological process | GLUD1, GLYATL1, GMPS, ASNSD1, CPS1, GFPT1, SIRT4, ASNS, CTPS1, MECP2, ADSS1, PHGDH, PPAT, GLS2, GLS, PFAS, CAD, CTPS2 |
| glutamine secretion | biological process | SLC1A5 |
| glutamine transport | biological process | SLC1A5, SLC38A7, SLC38A6, SLC38A1, SLC1A4, SLC38A2, SLC38A5, SLC38A3 |
| glutaminyl-tRNA aminoacylation | biological process | LARS1, QARS1 |
| glutaminyl-tRNAGln biosynthesis via transamidation | biological process | QRSL1, GATB, GATC |
| glutamyl-tRNA aminoacylation | biological process | EPRS1, EARS2 |
| glutathione biosynthetic process | biological process | MGST2, GCLC, CNDP2, GGCT, OPLAH, HAGH, CHAC1, GGT7, GGT1 |
| glutathione catabolic process | biological process | GGTLC1, GGTLC2, CHAC1, GGT7, GGT1, DPEP1 |
| glutathione derivative biosynthetic process | biological process | GSTM1, GSTP1, MGST1, GSTT1, GSTK1, MGST3, MGST2, AKR1A1, GSTA1, GSTO1, GSTO2, ESD, GSTZ1, GSTM4, GSTA3, HPGDS, GSTA4, GSTA2, GSTM5 |
| glutathione metabolic process | biological process | SOD1, GSTM1, GSR, GPX1, GSTP1, MGST1, GSTT1, GSTK1, GDAP1L1, IDH1, G6PD, GLO1, CTNS, GCLC, GLRX2, ETHE1, GSTA1, OPLAH, GSTZ1, GSTM4, GSTA3, NAT8, NFE2L1, HPGDS, GGT7, GGT1, MMACHC, DPEP1, GSTA4, GSTA2, GSTM5 |
| glutathione transport | biological process | SLC9A3R1 |
| glyceraldehyde-3-phosphate biosynthetic process | biological process | TKT, TPI1 |
| glyceraldehyde-3-phosphate metabolic process | biological process | TALDO1, TPI1 |
| glycerol biosynthetic process | biological process | LEP, GOT1, PGP |
| glycerol biosynthetic process from pyruvate | biological process | PCK2 |
| glycerol catabolic process | biological process | GK2, GK, TKFC, TPI1, GK5, GPD2 |
| glycerol ether metabolic process | biological process | TXNDC8, TXNDC2, TXN2 |
| glycerol metabolic process | biological process | GK2, MOGAT1, GK, COQ3, TKFC, DGAT2, ANGPTL3, GK5, PLA2G4A, MYOF, MOGAT2, DYSF, MOGAT3 |
| glycerol transport | biological process | AQP5, AQP7, AQP2, AQP11, AQP9, AQP3, AQP1, AQP10 |
| glycerol-3-phosphate biosynthetic process | biological process | GK2, GK, GK5 |
| glycerol-3-phosphate catabolic process | biological process | GPD1L |
| glycerol-3-phosphate metabolic process | biological process | GK2, GK, GPD1L, GPAM, GPD2 |
| glycerolipid metabolic process | biological process | DGKK, DGKE, DGKB, DGKI, DGKA, DGKG, DGKZ, DGAT1, DGKH, DGKQ, DGKD, AGK |
| glycerophosphate shuttle | biological process | GPD2 |
| glycerophospholipid biosynthetic process | biological process | CPNE3, AJUBA, CPNE1, HDHD5, FAR1, CLN3, CPNE6, CRLS1, CPNE7, AGK |
| glycerophospholipid catabolic process | biological process | PLA2G4C, GDPD3, ABHD12, PRDX6, GPCPD1, PLA2G4A, PNPLA6, GDE1, SMPD4, ENPP6, GDPD1 |
| glycerophospholipid metabolic process | biological process | GNPAT, PEMT, PIP5K1A, PNPLA3, PGP, PLA2G4A, PLA2G15, GPAM |
| glycine betaine transport | biological process | SLC38A2 |
| glycine biosynthetic process | biological process | SHMT1, SHMT2 |
| glycine biosynthetic process from serine | biological process | SHMT1, SHMT2 |
| glycine biosynthetic process, by transamination of glyoxylate | biological process | AGXT |
| glycine catabolic process | biological process | GLDC, GCSH, AMT |
| glycine decarboxylation via glycine cleavage system | biological process | GLDC, GCSH, AMT |
| glycine import | biological process | SLC6A20 |
| glycine import across plasma membrane | biological process | SLC6A5 |
| glycine import into mitochondrion | biological process | SLC25A38 |
| glycine metabolic process | biological process | GLDC, SHMT1, GART, GLYAT, BAAT, SHMT2, PHGDH |
| glycine receptor clustering | biological process | GPHN |
| glycine secretion, neurotransmission | biological process | SLC6A9 |
| glycine transport | biological process | SLC6A20, SLC36A1, SLC36A2, SLC36A3, SLC6A9, SLC6A5, SLC38A5, SLC32A1, SLC6A17 |
| glycogen biosynthetic process | biological process | AKT1, UGP2, GYG1, GYS2, PGM2L1, PGM1, GBE1, AGL, PPP1R3C, PER2, GYG2, PHKG2, PGM2, NR1D1, GYS1, PHKG1, AKT2 |
| glycogen catabolic process | biological process | GAA, PHKB, PGM2L1, PGM1, AGL, CALM1, PHKG2, PGM2, PHKA2, STBD1, PYGL, PYGB, PHKG1, PYGM |
| glycogen cell differentiation involved in embryonic placenta development | biological process | AKT1 |
| glycogen metabolic process | biological process | IL6ST, AKT1, GSK3B, GAA, UGP2, PHKB, PPP1R2, GNMT, PPP1R3D, PRKAG2, GBE1, PPP1CB, AGL, PPP1R3C, PPP1R1A, STK40, PHKG2, PPP1R3B, PHKA2, STBD1, PYGL, PYGB, PCDH12, GYS1, PHKG1, AKT2, PYGM |
| glycolate biosynthetic process | biological process | PARK7 |
| glycolate catabolic process | biological process | HAO1 |
| glycolate metabolic process | biological process | IGF1 |
| glycolipid biosynthetic process | biological process | SCCPDH, GAL3ST3, B3GNT5, ST3GAL4, ST3GAL6, GAL3ST2, ST3GAL2, GAL3ST4 |
| glycolipid catabolic process | biological process | FUCA1, NAGA |
| glycolipid metabolic process | biological process | PSAP, ST6GALNAC4, ST3GAL6, FUT2 |
| glycolipid translocation | biological process | RFT1 |
| glycolipid transport | biological process | NPC2, CPTP, GLTP, CLN3, PLEKHA8 |
| glycolytic process | biological process | GAPDH, ENO1, PGK2, GAPDHS, PGK1, PGAM1, PGAM4, LDHA, ADPGK, PFKM, PFKP, OGDH, PGM1, ENO2, PKM, PFKFB2, ALDOB, BPGM, HKDC1, ALDOA, PGAM2, TPI1, GPI, HK2, ENO3, OGDHL, ALDOC, PFKL, GCK, HK3, DHTKD1, PKLR |
| glycolytic process from galactose | biological process | GALK1 |
| glycolytic process through fructose-6-phosphate | biological process | PFKM, PFKL |
| glycophagy | biological process | RB1CC1, STBD1 |
| glycoprotein biosynthetic process | biological process | LARGE1, GOLPH3, GCNT1, B4GALT1, TNIP1, ST3GAL4, FKRP, B3GNT6, GAL3ST2, ST3GAL2, GAL3ST4 |
| glycoprotein catabolic process | biological process | MGEA5, NGLY1, EDEM3, FBXO17, STT3B, FBXO2, ADAMTS9, MANBA, FBXO6, FBXO44, NEU4 |
| glycoprotein metabolic process | biological process | IL1B, ST6GALNAC6, ASGR2, MAN1A2, PCSK6, ERP44, ADAMTS13, SLC34A1, ST6GALNAC3, ST8SIA3, GAL3ST4 |
| glycoprotein transport | biological process | GUK1, ABCG1, VLDLR, SLC10A7 |
| glycosaminoglycan biosynthetic process | biological process | HEXA, GPC2, PXYLP1, EXT1, GPC5, HS3ST3A1, UGDH, SDC2, SLC35D2, B3GALT6, SDC4, XYLT2, GPC6, HS3ST2, GALNT5, XYLT1, GCNT2, NDST1, HSPG2, EXT2, NDST2, HS3ST3B1, GPC4, PDGFRB, HS3ST1, GPC1, GPC3, AGRN, HAS1, B3GAT3, HS6ST1, SDC3, SDC1, HS2ST1, HS6ST2, HS3ST6 |
| glycosaminoglycan catabolic process | biological process | GLB1, FUCA1, GPC2, HPSE, IDS, GPC5, GUSB, SDC2, SDC4, HPSE2, GPC6, SGSH, HGSNAT, LYVE1, GNS, HSPG2, HYAL2, GPC4, IDUA, GPC1, GPC3, NAGLU, AGRN, SDC3, SDC1 |
| glycosaminoglycan metabolic process | biological process | DCN, HEXB, B3GAT1, B3GALT6, XYLT2, XYLT1, CHST9, B3GAT2, NDST1, GNS, FOXC1, B3GAT3, CLN6 |
| glycoside catabolic process | biological process | FUCA1, GLA, NAGA, FUCA2, GBA2 |
| glycoside metabolic process | biological process | TH |
| glycosphingolipid biosynthetic process | biological process | B4GALNT1, LARGE1, A4GALT, ST8SIA1, ST6GALNAC5, ST8SIA5, ST8SIA3 |
| glycosphingolipid catabolic process | biological process | GLA |
| glycosphingolipid metabolic process | biological process | BAX, HEXA, HEXB, KIT, ASAH1, ARSA, CREM, GBA, GLB1, ST6GALNAC6, B3GALNT1, GLA, B4GALNT1, SMPD1, PSAP, GALC, CTSA, SMPD3, CERK, ESYT2, CPTP, GBA2, GLTP, NEU1, SMPD2, SUMF2, ESYT1, SMPD4, SUMF1, ESYT3, NEU4, ENPP7, NEU2, ST6GALNAC3, UGCG, STS, GM2A, UGT8 |
| glycosylation | biological process | NANS |
| glycosylceramide catabolic process | biological process | GLA, NAGA |
| glycosylceramide metabolic process | biological process | ST6GALNAC6, ST6GALNAC3 |
| glycyl-tRNA aminoacylation | biological process | GARS1 |
| glyoxal catabolic process | biological process | PARK7 |
| glyoxylate catabolic process | biological process | AGXT, HOGA1 |
| glyoxylate cycle | biological process | IDH1, IDH2 |
| glyoxylate metabolic process | biological process | DAO, GRHPR, PRODH2, AGXT, ALDH4A1, GOT2, HOGA1, HYI |
| GMP biosynthetic process | biological process | GMPS, IMPDH2, IMPDH1 |
| GMP catabolic process | biological process | HPRT1, PRTFDC1 |
| GMP metabolic process | biological process | GMPR2, GUK1, DLG1, CASK, MPP1, LRGUK, MAGI3, CARD11, DLG2 |
| GMP salvage | biological process | HPRT1 |
| Golgi apparatus mannose trimming | biological process | MAN1A2, MAN1C1, MAN1A1 |
| Golgi calcium ion homeostasis | biological process | TMEM165, ATP2C1 |
| Golgi calcium ion transport | biological process | TMEM165, ATP2C1 |
| Golgi disassembly | biological process | CDK1, STX5, GBF1, PLK3, GOLGA2 |
| Golgi localization | biological process | ARCN1, STK25, HOOK3, ARHGAP21 |
| Golgi organization | biological process | CDC42, DYNC2H1, USO1, OPTN, TMED5, CSNK1A1, HIKESHI, USP6NL, ARFGEF1, GOLGA8A, RAB29, SURF4, ZW10, ATP8B3, ATP8B4, TRAPPC12, RAB1A, ATP8B2, ARHGEF7, LMAN2L, BLZF1, SPTBN5, SEC16A, RAB2A, PRKD1, DYM, TRAPPC11, PI4K2B, LMAN1, UBXN2A, LMAN2, DNAJC28, BAG5, TMED6, TBC1D20, COG4, STX17, GORASP1, CSNK1D, TMED2, RAB30, TJAP1, ZFP69B, GOLGA6B, MYO18A, NSFL1C, GOLGA8N, TRIP11, LYSMD3, GOLGA8M, ARHGAP21, ATL3, GOLPH3L, GOLPH3, ARL1, UBXN2B, TICAM2, HACE1, KIFC3, TMED7, OBSL1, TMED10, PI4K2A, GOLGB1, BHLHA15, BCAS3, VPS51, GAK, FAM174B, HTT, COG7, CUL7, TMED4, FBXW8, COG1, TMED9, CLASP2, COG3, TRAPPC8, GOLGA5, GBF1, ZNF501, TANGO2, ATL2, ATP8B1, GOLGA2, PLEKHM2, SYNE1, CLASP1, COG2, NPLOC4, LMAN1L, LRRK2, VMP1, SEC16B, TMED1, GOLGA6A |
| Golgi reassembly | biological process | PDCD10, STK25, YWHAZ |
| Golgi ribbon formation | biological process | OPTN, TMED5, FHDC1, VAMP4, MYO18A, TRIP11, STX16, GOLPH3, GCC2, VTI1A, GOLGA2 |
| Golgi to endosome transport | biological process | DOP1A, EPS15, VPS13C, KIF16B, RAB14, KLHL20, SORT1, AP4M1, CORO7, GBF1, AP2A1, DOP1B, MON2 |
| Golgi to lysosome transport | biological process | CCDC91, AP1G1, ANKFY1, GAK, LAMP1, CLN3, AP4M1, EHD3 |
| Golgi to plasma membrane CFTR protein transport | biological process | SEC16A, KRT18 |
| Golgi to plasma membrane protein transport | biological process | OPTN, BBS2, ANK3, BLZF1, NSF, GOLGA7, MACF1, SPTBN1, RAB31, GGA3, VAMP4, GOLGA4, VAMP3, AMN, GOLPH3L, GOLPH3, RAB26, VAMP7, PREPL, GCC2, GGA2, GGA1, ARFRP1, RAB34, VAMP5, C16orf70, BBS1, KIF13A |
| Golgi to plasma membrane transport | biological process | GOPC, RABEP1, CCDC93, RAB3IP, EXOC6B, GOLGA7, ARFGEF2, ARL3, STXBP6, OSBPL5, EXOC6, LLGL1, VPS35L, COMMD1, STEAP2, EXOC5, EXOC8, EXOC4, EXOC1, CCDC22, GGA1, EXOC2 |
| Golgi to secretory granule transport | biological process | BICDL1 |
| Golgi to transport vesicle transport | biological process | ARF1 |
| Golgi to vacuole transport | biological process | VPS52, VTI1B, AP1G1, AP3D1, AP1G2, GOSR2, VTI1A |
| Golgi vesicle budding | biological process | MYO18A, GOLPH3L, GOLPH3 |
| Golgi vesicle docking | biological process | USO1, NSF |
| Golgi vesicle fusion to target membrane | biological process | RAB8B, RAB8A, NKD2 |
| Golgi vesicle prefusion complex stabilization | biological process | DNAJC28, COG4 |
| Golgi vesicle transport | biological process | ARCN1, VPS41, CCDC91, CYTH3, STX10, TRAPPC3, PRKD1, CUX1, CUX2, TRAPPC3L, TRAPPC5, ARL1, VPS51, RINT1, GOLGA5, SLC10A7, TRAPPC6B |
| gonad development | biological process | AMH, WT1, FSHR, NR0B1, FGF8, WDR19, MKKS, BASP1, IRX5, RDH10, SALL1 |
| gonadal mesoderm development | biological process | AMH, TSPY1, ZFPM2, TSPY3, TSPY10, TSPY4 |
| gonadotrophin-releasing hormone neuronal migration to the hypothalamus | biological process | SEMA3A, NRP2, NRP1 |
| gonadotropin secretion | biological process | NIBAN2 |
| GPI anchor biosynthetic process | biological process | PGAP3, PIGX, PIGA, PIGH, PIGS, PYURF, PIGM, PIGP, PIGO, PIGV, PIGN, PIGF, PGAP1, PIGB, GPAA1, PIGG, PIGL, DPM2, PIGW, PIGQ, PIGY, PIGK, PIGT, PIGU, DPM1, PGAP2 |
| GPI anchor metabolic process | biological process | PGAP3, PGAP1, PIGW |
| GPI anchor release | biological process | GPLD1 |
| granulocyte chemotaxis | biological process | CCL3, ANXA1, IL17RA, ADGRE2 |
| granulocyte colony-stimulating factor production | biological process | LILRA2 |
| granulocyte colony-stimulating factor signaling pathway | biological process | CEACAM1 |
| granulocyte differentiation | biological process | SPI1, SP3, CBFA2T3, NKAP, CEBPE, SRP54, CSF3, L3MBTL3, ZFPM1 |
| granulocyte macrophage colony-stimulating factor biosynthetic process | biological process | IL18 |
| granulocyte macrophage colony-stimulating factor production | biological process | LILRA2 |
| granulocyte migration | biological process | JAM3 |
| granuloma formation | biological process | UNC13D |
| granulosa cell development | biological process | BMP15 |
| granulosa cell differentiation | biological process | FOXL2 |
| granzyme-mediated apoptotic signaling pathway | biological process | GZMB, GZMH, SRGN, BNIP3, UBE4B, LAMP1 |
| grooming behavior | biological process | OXT, PPT1, CTNS, QRFP, SLITRK5, APRT, HPRT1, NMUR2, AVP, DRD1, DDO, HOXB8, DRD2 |
| growth | biological process | TGFB1, INHBA, BCL2, TGFB3, VEGFA, CCNB2, BMP7, MTOR, BMP4 |
| growth factor dependent regulation of skeletal muscle satellite cell proliferation | biological process | FGF2 |
| growth hormone receptor signaling pathway | biological process | STAT3, GH1, JAK2, SOCS2, PIK3R1, PXN, PTK2, CSHL1, GH2, GHR, CSH1, CSH2 |
| growth hormone secretion | biological process | GHRL, RAB1A, GHSR, LTBP4 |
| growth involved in heart morphogenesis | biological process | NOTCH1, MESP1 |
| growth of symbiont in host | biological process | PGLYRP2 |
| growth plate cartilage chondrocyte development | biological process | COL27A1 |
| growth plate cartilage chondrocyte differentiation | biological process | IFT80, NPPC |
| growth plate cartilage chondrocyte growth | biological process | TGFBR2, RARG |
| growth plate cartilage chondrocyte morphogenesis | biological process | MATN4, COL12A1, MATN2, COL7A1, COL6A1, VWA2, COL6A2, SCARA3, MATN3, MBL2, COL6A3, VIT, VWA1, COL20A1, COCH |
| growth plate cartilage chondrocyte proliferation | biological process | CER1, NPPC |
| growth plate cartilage development | biological process | RARB, ZMPSTE24, IFT80, MMP13, TGFBR2, RARG, COMP, THBS3, RARA |
| GTP biosynthetic process | biological process | NME8, NME7, NME5, NME9, NME6, NME2, NME3, IMPDH2, IMPDH1, NME1, NME4 |
| GTP metabolic process | biological process | GNAI3, AK4, GTPBP1, EFL1, OPA1, MFN1, RAB23, RHOQ, RAN, AK3, AMPD3, LRRK2, GIMAP7 |
| guanine catabolic process | biological process | GDA |
| guanine metabolic process | biological process | GDA |
| guanine salvage | biological process | HPRT1, PRTFDC1 |
| guanine transport | biological process | SLC29A2 |
| guanosine metabolic process | biological process | DGUOK |
| guanylate kinase-associated protein clustering | biological process | NRXN1 |
| habenula development | biological process | NR4A2, POU4F1 |
| habituation | biological process | KALRN, DGKI, DRD1, SHANK1 |
| hair cell differentiation | biological process | ERCC2, CTNNB1, SPINK5, USH2A, PITX2 |
| hair cycle | biological process | PTGS2, KRTAP4-5, SNRPE, PTCH2, MPZL3, KRT83, SOX21, KRTAP4-8, KRT14, PPP1R13L |
| hair cycle process | biological process | ERCC2, CTNNB1, SOX18, FARP2, CDH3, LRIG1 |
| hair follicle development | biological process | EGFR, INHBA, SOX9, SOS1, SHH, TP63, ACVR1B, LGR4, ZMPSTE24, SOX18, NSDHL, WNT10A, KRT84, FOXN1, FZD3, TNFRSF19, RELA, DKK1, CELSR1, PDGFA, TGFB2, ZDHHC21, SAV1, VANGL2, ALX4, EDA, CD109, EDAR, SOX21, LDB2, FZD6, APCDD1, FUZ, LAMA5, LGR5, HOXC13, LRP4, DSG4, LHX2 |
| hair follicle maturation | biological process | ERCC2, NSUN2, NOM1, TRPC4AP, MYO5A, RBPJ, NF1 |
| hair follicle morphogenesis | biological process | BCL2, FGFR2, CTNNB1, CDC42, SHH, TP63, TMEM79, WNT10A, INTU, NOTCH1, KRT71, GORAB, SMO, TGFB2, SOSTDC1, ATP7A, KRT17, FGF7, FOXE1, NGFR, IGFBP5, GLI2, TGM3, FGF10, FOXQ1 |
| hair follicle placode formation | biological process | GNAS, CTNNB1, CDC42, HDAC2, EDA |
| halogenated hydrocarbon metabolic process | biological process | CYP2E1 |
| hard palate development | biological process | FZD2, SOX11, DLG1, MMP25, FOXE1, FZD1 |
| hard palate morphogenesis | biological process | NEUROG1, TIFAB |
| Harderian gland development | biological process | SOX9, ALDH1A3, RARG, FGF10 |
| head development | biological process | EDNRA, FLRT3, SSBP3, PGAP1, LHX1, MMP14, DLX6, DLX5, IL11RA, TRABD2A, GLI2, STRA6, RPGRIP1L, OSR2 |
| head morphogenesis | biological process | ATP6AP2, FLVCR1, SSBP3, DKK1, ANKRD11, IHH, WNT3, STRA6 |
| heart contraction | biological process | SOD1, ACE, GPX1, CDC42, DNM1L, TRDN, ACTC1, ATG5, SGCD, MYL2, NKX2-5, SGCZ |
| heart development | biological process | WT1, ADM, SOX9, ERBB2, MTHFD1, MAPK1, CASP3, MDM2, ATM, NODAL, MBD1, EDNRA, CTNNB1, PTEN, BMP4, NRG1, RAF1, PCNA, GJA1, OXTR, PPARG, FGF8, MEF2A, PTPN11, SHH, FLRT3, OXT, PKD1, DYNC2H1, DNAH5, DNAH11, GLI3, PAM, FGF12, COX17, KCNAB1, ARMC4, ZFPM2, OVOL2, SENP2, SRI, MYH10, ISL1, NEK8, MIB1, RB1CC1, FOXJ1, IFT74, ZDHHC16, TDGF1, SHC1, PTK7, NCOA6, PDGFB, EEF1AKMT4-ECE2, PTN, FBN1, ECE1, PPARD, CALCRL, BCOR, BVES, NKX3-1, CPLANE1, SOX18, ACVR1, POPDC3, HDAC9, COL3A1, PPP3CB, BMPR1A, MKKS, PDLIM1, RAMP2, CACNA1C, PDLIM2, ADAP2, NOTCH1, ACVR2B, MSX1, IRX4, ID3, TEK, MEF2C, PKD2, FREM2, ADIPOR2, DNAAF4, ACAN, GRK2, OXCT1, MIXL1, PSEN1, ASCL1, PLCE1, SALL4, CACYBP, NRP2, EPOR, LOX, CRIP1, NDST1, TGFB2, LRP2, EP300, NIPBL, TBX5, TAB2, MOSPD3, GNA11, CDKN1B, CSRP3, AP2B1, PRKDC, TBC1D32, XIRP2, DVL2, CFC1B, CXADR, RBPJ, SYPL2, FOXC2, TGFBR1, AKAP13, TFDP2, POPDC2, SOX4, ZFP36L1, SMAD2, MYOCD, PDLIM5, CITED2, HEY2, LDB3, MB, CDKN1A, RIPPLY3, CDKL1, POU4F1, AP1B1, NFATC4, ALPK3, PKP2, PDLIM7, MBD3, ERBB3, GJA5, ID2, MA |
| heart formation | biological process | BMPR1A, LEMD2 |
| heart looping | biological process | HIF1A, NODAL, GJA1, GATA4, FGF8, SHH, CCDC103, DNAAF1, OVOL2, IFT57, MIB1, IFT52, BBS5, SETDB2, EOMES, SOX18, AHI1, NDRG4, MKKS, NOTCH1, WNT3A, MEF2C, PKD2, TBR1, BBS4, TMED2, ARL13B, PSEN1, SMO, C2CD3, VANGL2, SUFU, TBX3, NPHP3, TBX20, TBX21, SRF, TGFBR2, LBX1, STIL, DLL1, ZIC3, MICAL2, ENG, MESP1, TBX6, NKX2-5, IHH, CCDC40, FOXN4, SMAD3, IFT172, FOXH1, FOLR1, HAND2, TBX2 |
| heart morphogenesis | biological process | VEGFA, MTOR, TGFBR3, INSR, FGF8, SOS1, CHD7, ALDH1A2, GAA, COL11A1, ARID2, ISL1, ASXL1, ZMPSTE24, PTK2, DCHS1, DLC1, ZMIZ1, BMPR1A, TAB1, SMARCD3, ALPK2, COL2A1, MYBPC3, FLRT2, MSX1, SMO, TGFB2, NIPBL, CERT1, DVL2, LEFTY1, FOXC2, TBX3, TH, COL5A1, MYL2, FOXC1, MESP1, NKX2-5, TREX1, EPHB4, PTCH1, TBX19, HTR2B, HAND2, TBX2 |
| heart process | biological process | SGCD, PPCS, YAP1, WWTR1, TREX1 |
| heart trabecula formation | biological process | TGFBR3, ADAMTS1, OVOL2, TEK, CAV3, FHL2, EGLN1, HEY2, SRF, HEY1, RBP4, NKX2-5 |
| heart trabecula morphogenesis | biological process | SOS1, NACA, S1PR1, NOTCH1, BMP5 |
| heart valve development | biological process | SOX9, MDM2, MATR3, MDM4, PRDM1, SMAD6, ZBTB14, PDE2A, HECTD1 |
| heart valve formation | biological process | SOX9 |
| heart valve morphogenesis | biological process | SOX9, MTOR, ADAMTS9, TGFB2 |
| heat generation | biological process | ADRB2, ADRB1 |
| helper T cell diapedesis | biological process | CRK, CRKL |
| helper T cell enhancement of adaptive immune response | biological process | CD4 |
| helper T cell extravasation | biological process | CCL2 |
| hematopoietic or lymphoid organ development | biological process | ASXL1, LTBR |
| hematopoietic progenitor cell differentiation | biological process | TGFB1, INHBA, BMP4, TOP2A, SIN3A, FST, SIPA1L3, TMEM190, KRT75, RBM47, SBDS, ADAR, BVES, ACP6, PLEK, PLD4, PTPN6, ARL11, SSBP3, EEF2, REST, ANLN, HEATR9, ZBTB24, FSTL3, MIXL1, WDR7, PTPRC, PSEN1, SLC8A3, SMPD3, TENT2, CDK6, WDR78, PRRC2C, SLC7A6OS, C12orf29, PYGO1, HYAL2, RRS1, MMP21, ZNF784, EML1, PDGFRB, CIAO3, HOXB3, PDGFRA, PTPRZ1, KCNAB2, TNFRSF13B, CSF1R, DHTKD1, ARMC6, TMEM91, ZFAT, STON2, CEBPD, TP53, DACT2 |
| hematopoietic stem cell differentiation | biological process | ACE, ERCC2, CHD2, XRCC5, BATF, MLLT3, CDK6, HOXB4, LMBR1L, SRF, SP7, TP53 |
| hematopoietic stem cell homeostasis | biological process | ADAR, CCN3, NLE1, TCIRG1, UBAP2L |
| hematopoietic stem cell migration | biological process | KIT, BCL11B, GPLD1 |
| hematopoietic stem cell migration to bone marrow | biological process | GAS6, JAM3, GPLD1, JAM2 |
| hematopoietic stem cell proliferation | biological process | ARIH2, CD34, SART3, RUNX1, NKAP, WNT2B, YJEFN3, YTHDF2, SFRP2, MECOM, WNT10B |
| heme a biosynthetic process | biological process | COX10 |
| heme biosynthetic process | biological process | PPOX, COX10, IBA57, TMEM14C, FXN, SLC25A38, FECH, UROD, PGRMC1, HMBS, ATP5IF1, ALAD, SLC25A39, NFE2L1, UROS, ALAS1 |
| heme catabolic process | biological process | HMOX1, UGT1A4, BLVRB, HMOX2, BLVRA, AMBP |
| heme export | biological process | FLVCR2, FLVCR1 |
| heme metabolic process | biological process | HMOX1, UROD, BDH2 |
| heme O biosynthetic process | biological process | COX10 |
| heme oxidation | biological process | HMOX1, HMOX2 |
| heme transmembrane transport | biological process | ABCB6 |
| heme transport | biological process | PGRMC2, FLVCR1, SLC48A1, ABCB6, HRG, ABCB7 |
| hemidesmosome assembly | biological process | ITGA6, LAMC1, PLEC, LAMC2, CD151, DST, ITGB4, LAMB3, LAMA3, COL17A1, KRT14 |
| hemoglobin biosynthetic process | biological process | INHBA, HIF1A, INHA, EPO, ALAS1 |
| hemoglobin metabolic process | biological process | CAT, AHSP, EPB42, ADD1 |
| hemolysis by symbiont of host erythrocytes | biological process | ALB |
| hemopoiesis | biological process | BCL2, IL10, BRCA2, CTNNB1, HSPA9, KIT, CSF1, ETV2, GLRX5, AHSP, ASH2L, ZNF160, SH2B3, PGM3, CIAPIN1, ASXL1, PDGFB, KIRREL3, CD34, L3MBTL1, FOXN1, WNT3A, RUNX1, PICALM, MKNK2, TIPARP, NKAP, MIXL1, MELK, CDK13, ANGPT1, TTC7A, BMI1, TGFB2, CDK6, ZFP36L2, CD164, ADD2, RBPJ, TWSG1, LYN, SOX6, GATA2, FLCN, EPAS1, HOXB4, PKNOX1, SELPLG, NOTCH4, ROGDI, MEIS1, RUNX2, MECOM, DLL1, LCK, ZBTB16, NKX2-5, GFI1, CSF1R, JAG1, ZFAT |
| hemostasis | biological process | F10, SERPINC1, VWF, TFPI2, SERPINA1, F5, F3, PLAU, F2R, ANXA5, F2RL3, GP1BB, ANXA7, ZNF385A, TFPI, PROC, GP6, THBD, F7, FGG, PROS1, GP9, HPS4, F12, P2RY12, FGB, GPI, F8, AVPR2, P2RY1, NFE2, F2RL2, PLG, FGA, HRG, SERPING1, SERPINA10, GP1BA, ADAMTS13, TSPAN32, PROCR, F2, PROZ, FLI1, ANXA8 |
| heparan sulfate proteoglycan biosynthetic process | biological process | DSE, NDST4, EXT1, EXTL2, UGDH, B3GALT6, XYLT2, GLCE, XYLT1, NDST1, VANGL2, NDST3, EXT2, NDST2, HS3ST3B1, EXTL3, B3GAT3, HS6ST1 |
| heparan sulfate proteoglycan biosynthetic process, enzymatic modification | biological process | HS6ST3, HS3ST3B1, HS6ST1, HS2ST1, HS6ST2 |
| heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | biological process | NDST4, EXT1, CSGALNACT1, NDST1, NDST3, EXT2, NDST2, HS2ST1 |
| heparan sulfate proteoglycan catabolic process | biological process | HPSE, SGSH, GPC1 |
| heparan sulfate proteoglycan metabolic process | biological process | SULF1, SULF2, HS3ST4 |
| heparin biosynthetic process | biological process | NDST4, CSGALNACT1, XYLT2, GLCE, ANGPT1, NDST1, NDST3, NDST2, SLC10A7 |
| heparin catabolic process | biological process | IDUA |
| hepatic immune response | biological process | IL6, IL6R |
| hepatic stellate cell activation | biological process | AKAP12 |
| hepatoblast differentiation | biological process | HNF1B |
| hepatocyte apoptotic process | biological process | FAS, RB1, STK3, STK4, KRT18, BID, PIK3CG, ARF6, BCL2L1, KRT8 |
| hepatocyte cell migration | biological process | PROX1 |
| hepatocyte dedifferentiation | biological process | HNRNPD |
| hepatocyte differentiation | biological process | CYP1A1, HNF1B, CPS1, ANXA1, PCK2, ITGA2, TAF10, E2F7, E2F8, HNF4A, PROX1 |
| hepatocyte growth factor receptor signaling pathway | biological process | HGF, STMN1, BCAR1, HPN, SIRT2, RAC1, MST1, MST1R, NRP1, MUC20 |
| hepatocyte proliferation | biological process | FGL1, RPS6KA1, PROX1 |
| hepoxilin biosynthetic process | biological process | ALOX5, ALOXE3, ALOX15B, ALOX12B |
| heterochromatin assembly | biological process | POLE3, HMGA2, BAHD1 |
| heterochromatin assembly by small RNA | biological process | FAM172A, NRDE2, ZNFX1 |
| heterochromatin maintenance | biological process | MTHFR, HDAC2 |
| heterochromatin organization | biological process | SETDB2, LOXL2, HP1BP3, SETD7, SETDB1, MECOM, PRDM16 |
| heterochromatin organization involved in chromatin silencing | biological process | SMCHD1 |
| heterocycle metabolic process | biological process | CYP1A1, CYP1A2, CYP2C19, CYP2E1, CYP2D6 |
| heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | biological process | ICAM1, ITGA5, IL1RAPL1, ADGRL1, VCAM1, REG3A, DCHS1, NRXN1, CEACAM8, CD209, UMOD, SELP, CEACAM6, TENM2, CD164, AMIGO3, NECTIN4, CXADR, CRB1, ALCAM, CRTAM, NECTIN1, SCARF2, GRID2, CRB2, AMIGO2, JAML, PVR, CD6, LGALS7, CDH4, CADM3, ITGAL, TENM4, AMIGO1, TENM3, PTPRD, IGSF21 |
| heterotrimeric G-protein complex assembly | biological process | PDCL |
| heterotypic cell-cell adhesion | biological process | ITGB1, ITGA5, ITGAV, ITGA4, VCAM1, CD47, CD58, JAM3, GLDN, MADCAM1, NRCAM, PTPRC, ITGB3, NFASC, PERP, PARVA, CD2, ITGAX, ITGB7, CD200R1, ITGB2, ITGA7, ITGAD |
| hexadecanal metabolic process | biological process | ALDH3A2 |
| hexose biosynthetic process | biological process | CHST15 |
| hexose metabolic process | biological process | HKDC1, GALM, HK2, GCK, HK3 |
| hexose transmembrane transport | biological process | SLC2A10, SLC2A8, SLC2A11, SLC50A1, SLC5A2, SLC5A10, SLC2A6, SLC2A7, SLC5A9 |
| high-density lipoprotein particle assembly | biological process | APOE, ZDHHC8, PRKACB, BMP1, APOA1, PRKACG, APOA5, ABCA7, APOM |
| high-density lipoprotein particle clearance | biological process | APOE, HDLBP, LDLR, SCARB1, APOA1, AMN, CUBN, APOM |
| high-density lipoprotein particle remodeling | biological process | APOE, LIPG, SCARB1, ABCG1, PLA2G3, LIPC, ABCA5, APOA1, APOC1, CETP, APOC3, APOM, LCAT |
| hindbrain development | biological process | HNF1B, CTNNB1, SHH, ALDH1A2, PTN, WLS, AHI1, NFIB, TBR1, NEUROD1, BMP5, GBX1, CEP290, EN1, GBX2, EN2, GLI2, PTF1A |
| hindbrain morphogenesis | biological process | HES1, DLC1 |
| hindbrain tangential cell migration | biological process | PHOX2B |
| hindgut development | biological process | IFT172 |
| hindgut morphogenesis | biological process | SHH, GLI3, GLI2 |
| hindlimb morphogenesis | biological process | BMPR1A, SALL3, TWIST1, HOXD10, ZBTB16, PTCH1, FMN1, GDF5 |
| hippo signaling | biological process | CASP3, NPHP4, PJA2, STK3, TJP1, STK4, DCHS1, AMOT, MOB1B, WWC1, LATS2, AMOTL2, YWHAE, SAV1, MOB1A, TEAD2, DVL2, TEAD1, LATS1, YWHAB, YAP1, TEAD4, WWTR1, TEAD3, AMOTL1 |
| hippocampus development | biological process | SRD5A2, ZEB2, CYP17A1, CASP3, GSK3B, EZH2, SRD5A1, NF2, MAS1, GLI3, KIF5B, BBS2, PPP1R9B, ALK, KDM6B, KIRREL3, EIF2B3, ANXA3, KIF14, PHLPP2, TSC1, XRN2, MKKS, BCAN, WNT3A, MDK, BBS4, FEZ1, TENT2, YWHAE, CDK5R1, UQCRQ, ID4, NCOA1, MFSD2A, LEF1, UBA6, CDK5R2, EIF2B5, LHX5, SRF, DRD1, SCT, CDK5, PTPRS, NME1, CRK, LMX1A, NR4A3, HTR5A, PLXNA3, DLX1, KCNA1, SLC32A1, CRKL, RELN, DLX2, NEFL, RARA, NKX2-1 |
| histamine catabolic process | biological process | HNMT |
| histamine metabolic process | biological process | TRH, HNMT, SLC22A3 |
| histamine secretion | biological process | EDNRA, ADA, EDN1 |
| histamine secretion by mast cell | biological process | SNAP23, LYN, BTK |
| histamine transport | biological process | SLC22A3 |
| histamine uptake | biological process | SLC22A2, SLC22A3 |
| histamine-induced gastric acid secretion | biological process | HRH2 |
| histidine biosynthetic process | biological process | MTHFD1, MTHFD2L |
| histidine catabolic process | biological process | AMDHD1, FTCD, HAL, CARNMT1, HNMT, UROC1 |
| histidine catabolic process to glutamate and formamide | biological process | AMDHD1, FTCD, HAL, UROC1 |
| histidine catabolic process to glutamate and formate | biological process | AMDHD1, FTCD, HAL, UROC1 |
| histidine metabolic process | biological process | AMDHD1, FTCD, HAL, UROC1 |
| histidine transport | biological process | SLC15A4, SLC38A3 |
| histidyl-tRNA aminoacylation | biological process | HARS1, HARS2 |
| histone acetylation | biological process | NCOA2, CLOCK, CDY2A, CDY1, MORF4L2, EPC2, SRCAP, DPF1, MORF4L1, RSF1, MRGBP, PCGF2, BAZ1A, RUVBL2, NCOA3, GTF2B, CREBBP, MSL3, MCM3AP, NAA50, TAF1, MECP2, EP300, PHF10, KAT5, RUVBL1, MEAF6, BRD8, ATF2, SGF29, HAT1, MBD3, KAT2A, KAT6A, KAT2B, KAT14, ING5, DPF2, KAT6B, ING4, GTF3C4 |
| histone arginine methylation | biological process | CARM1, PRMT2, PRMT8, PRMT7 |
| histone biotinylation | biological process | HLCS |
| histone citrullination | biological process | PADI1, PADI2, PADI3, PADI4, PADI6 |
| histone deacetylation | biological process | MTA2, SIN3A, HDAC4, MORF4L2, MTA3, MORF4L1, MIER3, MIER1, HDAC11, HDAC2, SIN3B, SUDS3, HDAC9, MSL3, HDAC8, SIRT2, MIER2, BAZ2A, HDAC7, RBM14, HDAC3, TBL1X, HDAC6, PRDM5, HDAC10, HDAC5, BRMS1 |
| histone demethylation | biological process | KDM6B, KDM4A, JARID2 |
| histone dephosphorylation | biological process | EYA4, PPP5C, EYA1, EYA2 |
| histone deubiquitination | biological process | ENY2, USP16, USP3, SUPT3H, USP51, USP22, USP36, TAF10, KAT2A, USP21, ATXN7 |
| histone displacement | biological process | BRDT |
| histone exchange | biological process | RNF8, NASP, SRCAP, DMAP1, SPTY2D1, ANP32E, ZNHIT1, ACTR6, PTMA, VPS72 |
| histone glutamine methylation | biological process | CREBBP, FBL, SIRT7 |
| histone H2A acetylation | biological process | MORF4L2, MORF4L1, ACTL6A, YEATS4, DMAP1, RUVBL2, MSL3, NAA40, ING3, RUVBL1, EPC1, MEAF6, BRD8, EP400 |
| histone H2A K63-linked deubiquitination | biological process | UIMC1, USP16 |
| histone H2A K63-linked ubiquitination | biological process | RNF8, RNF168 |
| histone H2A monoubiquitination | biological process | SKP1, RNF168, TRIM37, BCOR, DDB2, PCGF1, RYBP, RING1, DDB1, RNF2 |
| histone H2A phosphorylation | biological process | ZMPSTE24 |
| histone H2A ubiquitination | biological process | UBE2B, UBR2, RNF8, RNF168, DTX3L |
| histone H2A-K119 monoubiquitination | biological process | PCGF3, PCGF5, TRIM37, PCGF2, PCGF1, BMI1, RNF2 |
| histone H2A-K13 ubiquitination | biological process | RNF168 |
| histone H2A-K15 ubiquitination | biological process | RNF168 |
| histone H2A-K5 acetylation | biological process | SPHK2 |
| histone H2A-S1 phosphorylation | biological process | RPS6KA5 |
| histone H2A-S139 phosphorylation | biological process | HMGA2, MST1 |
| histone H2A-T120 phosphorylation | biological process | DCAF1 |
| histone H2B acetylation | biological process | ZMPSTE24, EP300 |
| histone H2B conserved C-terminal lysine deubiquitination | biological process | USP7, USP15, USP49 |
| histone H2B conserved C-terminal lysine ubiquitination | biological process | WAC |
| histone H2B ubiquitination | biological process | RNF8, RNF20, DTX3L, PAF1, CTR9, CDC73, RNF40, UBE2E1, LEO1 |
| histone H2B-K12 acetylation | biological process | SPHK2 |
| histone H2B-K5 acetylation | biological process | ZMPSTE24 |
| histone H3 acetylation | biological process | BRCA2, KAT7, TADA1, TADA3, JADE3, TAF5, TAF12, PER1, SPI1, DR1, POLE3, MAP3K7, MBIP, SUPT3H, WDR5, MCM3AP, SUPT7L, TAF6L, TAF5L, BRPF1, TADA2A, BRD1, TAF10, SGF29, LEF1, TRIM16, MYOD1, KAT2A, KAT6A, KAT2B, KAT14, ING5, YEATS2, KAT6B, NAA60, JADE2, ING4, TAF9, BRPF3 |
| histone H3 deacetylation | biological process | HDAC4, PER1, HDAC11, SFPQ, HDAC2, HDAC9, HDAC8, SIRT2, PER2, ATXN3, ELK4, HDAC7, HDAC3, SIRT6, SIRT7, HDAC6, SMARCAD1, HDAC5 |
| histone H3-K14 acetylation | biological process | BRPF1, MEAF6, BRD1, KAT2A, ING5, BRPF3 |
| histone H3-K23 acetylation | biological process | BRPF1, MEAF6 |
| histone H3-K27 demethylation | biological process | KDM6B, UTY, PHF8 |
| histone H3-K27 methylation | biological process | EZH2, EED, SUZ12, EHMT2, EHMT1 |
| histone H3-K27 trimethylation | biological process | H1-4, H1-2, CHD5, H1-3 |
| histone H3-K36 demethylation | biological process | RIOX2, KDM4A, RIOX1, KDM4C, PHF8, KDM2A, KDM4B, KDM8 |
| histone H3-K36 dimethylation | biological process | ASH1L |
| histone H3-K36 methylation | biological process | SETD3, NSD1, NSD3, NSD2, PRDM7, SMYD2 |
| histone H3-K36 trimethylation | biological process | SETD5 |
| histone H3-K4 acetylation | biological process | LDB1 |
| histone H3-K4 demethylation | biological process | KDM5C, KDM5D, KDM5B, RIOX2, RIOX1, KDM5A, KDM1B |
| histone H3-K4 demethylation, trimethyl-H3-K4-specific | biological process | KDM5B, JARID2, KDM5A |
| histone H3-K4 dimethylation | biological process | KMT2D, KMT2A, SETD1B, SETD1A, KMT2B |
| histone H3-K4 methylation | biological process | SETD3, DPY30, WDR82, ASH2L, CXXC1, RBBP5, WDR5, KMT2D, KMT2A, DYDC1, SETD1B, PAGR1, ASH1L, KMT2B, PAXIP1 |
| histone H3-K4 monomethylation | biological process | KMT2D, KMT2A, KMT2C, SETD1B, RLF, SETD1A, KMT2B |
| histone H3-K4 trimethylation | biological process | H1-4, WDR82, OGT, WDR61, RTF1, KMT2D, CTR9, H1-2, ZNF335, KMT2A, SETD1B, TET3, H1-3, TET2, PRDM7, SETD1A, KMT2B |
| histone H3-K79 methylation | biological process | DOT1L |
| histone H3-K9 acetylation | biological process | KAT2B |
| histone H3-K9 deacetylation | biological process | SIRT6 |
| histone H3-K9 demethylation | biological process | KDM4A, PHF2, KDM4C, KDM4D, KDM3B, PHF8, KDM4B, HR, HSF4 |
| histone H3-K9 dimethylation | biological process | SUV39H2 |
| histone H3-K9 methylation | biological process | SETDB2, EHMT2, EHMT1, SETD5, SETDB1, ASH1L, MECOM, PRDM5, PRDM16 |
| histone H3-K9 modification | biological process | SIRT6 |
| histone H3-K9 trimethylation | biological process | SUV39H2 |
| histone H3-R17 methylation | biological process | CARM1, NR1H4 |
| histone H3-R2 methylation | biological process | PRMT6, CARM1 |
| histone H3-R26 citrullination | biological process | PADI2, PADI4 |
| histone H3-S10 phosphorylation | biological process | RPS6KA5, DRD1, RPS6KA4 |
| histone H3-S10 phosphorylation involved in chromosome condensation | biological process | CCNB1 |
| histone H3-S28 phosphorylation | biological process | RPS6KA5, RPS6KA4, AURKB |
| histone H3-T11 phosphorylation | biological process | PKN1 |
| histone H3-T6 phosphorylation | biological process | PRKCB |
| histone H3-Y41 phosphorylation | biological process | JAK2 |
| histone H4 acetylation | biological process | BRCA2, TADA3, MORF4L2, MORF4L1, PER1, ACTL6A, YEATS4, DMAP1, RUVBL2, MSL3, USP22, NAA40, NAA50, CHD5, ING3, EP300, KAT5, NCOA1, RUVBL1, EPC1, BRD8, LEF1, HAT1, TRIM16, MYOD1, ACTL6B, APBB1, EP400, ING5, NAA60 |
| histone H4 deacetylation | biological process | HDAC4, HDAC2, HDAC9, REST, HDAC8, SIRT2, RCOR1, HDAC3, SIRT7, SMARCAD1 |
| histone H4-K12 acetylation | biological process | KAT7, JADE3, MEAF6, KAT2A, JADE2, ING4 |
| histone H4-K16 acetylation | biological process | KAT7, JADE3, OGT, KANSL1L, HCFC1, WDR5, MSL3, KANSL2, KMT2A, MSL1, KANSL1, PHF20, MEAF6, KANSL3, MCRS1, MSL2, JADE2, ING4 |
| histone H4-K16 deacetylation | biological process | HDAC9 |
| histone H4-K20 demethylation | biological process | PHF8 |
| histone H4-K20 methylation | biological process | NSD1, NSD2, KMT5A |
| histone H4-K20 trimethylation | biological process | PWP1, KMT5B, KMT5C |
| histone H4-K5 acetylation | biological process | KAT7, JADE3, OGT, KANSL1L, HCFC1, WDR5, KANSL2, KANSL1, PHF20, MEAF6, KANSL3, MCRS1, JADE2, ING4 |
| histone H4-K8 acetylation | biological process | KAT7, JADE3, OGT, KANSL1L, HCFC1, WDR5, KANSL2, KANSL1, PHF20, MEAF6, KANSL3, MCRS1, JADE2, ING4 |
| histone H4-R3 methylation | biological process | PRMT6, COPRS, PRDM4, PRMT1, PRMT7 |
| histone lysine demethylation | biological process | UBE2B |
| histone lysine methylation | biological process | PRDM9, NSD1, NSD3, SETDB2, EHMT2, SETD6, MEN1, EHMT1, SETD7, SETDB1, KMT2E, SUV39H2, TTLL12, SMYD1, KMT2B, SMYD2, KMT5A |
| histone methylation | biological process | EZH2, CTCFL, PRMT6, EED, PRDM13, CARM1, NSD1, NSD3, SUZ12, KMT5B, EHMT2, PRMT2, EHMT1, PRMT8, SATB1, MECP2, NTMT1, PRMT1, KMT5C, PRDM11, PRMT7, SMYD2 |
| histone modification | biological process | AURKC, PAF1, CTR9, CDC73, SIRT7, MT3, LEO1, HLCS, AURKB |
| histone monoubiquitination | biological process | RAG1, RNF20, WAC, DTX3L, PAF1, CTR9, CDC73, RNF40, UHRF1, UBE2E1, LEO1 |
| histone mRNA catabolic process | biological process | ATM, EXOSC10, TUT1, LSM1, MTPAP, DCP2, UPF1, ERI1, TENT2, XRN1, EXOSC4, TENT4B, TUT4, TENT4A, TUT7 |
| histone mRNA metabolic process | biological process | NCBP2, SSB, LSM11, NCBP1, ZNF473, SNRPE, SNRPB, SNRPG, SLBP, SNRPF |
| histone phosphorylation | biological process | CDK1, ATM, BAZ1B, NEK11, HIPK4, MAP3K12, PRKCD, RPS6KA5, CDK5, RPS6KA4, INCENP |
| histone succinylation | biological process | OGDH, KAT2A, DLST |
| histone ubiquitination | biological process | RNF20, PHC1, HUWE1, UBE2N, SUZ12, CBX8, USP22, UBE2U, UHRF1, RING1, RNF2 |
| histone-serine phosphorylation | biological process | AURKC, PRKAA2 |
| homeostasis of number of cells | biological process | BAX, BAK1, EMX1, ASXL1, BCR, SART3, GATA3, RASSF2, CYLD, RRN3, IL7R, WDR48, CCR7, LAT, POLB, TCIRG1, CARD11, ZFPM1, CCR4 |
| homeostasis of number of cells within a tissue | biological process | BCL2, SOX9, BAX, TEX15, F2R, PTPN11, CSF1, KLHL10, IL7, IL20RB, KRAS, LIPA, NOTCH1, SMO, ILDR2, FH, GATA2, P2RX7, ADD1, RAC3, GIGYF2, CORO1A, FLT3LG, GATA1 |
| homeostatic process | biological process | NR5A2, ARID2, WNT7B, CREBBP, SLITRK1, TRERF1, PKHD1, IL31RA, ANG, RHCG, MPV17 |
| homocysteine catabolic process | biological process | MTRR, CBS, BLMH |
| homocysteine metabolic process | biological process | MTHFR, CBS, CPS1, DPEP1 |
| homogentisate catabolic process | biological process | FAH |
| homoiothermy | biological process | DBH, MC3R |
| homologous chromosome movement towards spindle pole in meiosis I anaphase | biological process | FMN2 |
| homologous chromosome orientation involved in meiotic metaphase I plate congression | biological process | BRCA2 |
| homologous chromosome segregation | biological process | MLH1, ESPL1, PTTG2, SGO1, PLK1, SGO2 |
| homologous recombination | biological process | HDAC10 |
| homophilic cell adhesion via plasma membrane adhesion molecules | biological process | ITGB1, PCDH17, CDH1, CDH18, PKD1, DSCAML1, CNTN4, PCDH9, PCDHB9, PALLD, FAT1, CDH7, NPTN, MPZL2, KIRREL3, PCDHGB1, NEXN, TRO, DCHS1, CDH10, CDH19, ROBO4, PCDHB4, PCDHGA11, PCDHGA12, FAT3, CDHR1, PCDH11Y, ROBO2, IGSF9, CNTN2, PCDHB3, PCDHA2, PTPRT, PCDHGB7, PCDHGB3, PCDHGA8, PCDHGA10, CEACAM6, MYPN, CELSR2, CELSR1, PCDHGA1, PCDHA9, CDH12, DSG1, CDH17, PTPRM, NECTIN4, PCDHB8, PCDHGA4, PCDH10, PCDHB14, PCDHA1, DSCAM, SDK2, PCDHB16, PCDHB5, CDH6, DSC3, ESAM, PCDHB1, DSG2, NECTIN1, CDH9, PCDHB10, RET, CEACAM1, CDH5, CDH8, CDH11, CDH13, DSC2, PCDH20, CDHR5, PCDHB15, CLSTN1, PCDH8, PCDH1, AMIGO2, VSTM2L, PCDH12, PLXNB3, CDH16, PVR, PECAM1, DSG3, CD84, PCDHGB4, PCDHB12, CDH3, CDH4, CDH15, EMB, CADM3, CDHR4, PLXNB2, L1CAM, SDK1, AMIGO1, CDHR2, CELSR3, FAT2, PCDHA4, PCDHA12, IGSF9B, PCDHA8, PCDHA5, PCDHA13, DSG4, CDH24, CLSTN3, CDH23, TENM3, CDHR3, CDH26, IGSF21, CDH22, PCDHA7, PCDHA6, CNTN6, PCDHGB6, PCDHGB5, PCDHGB2, PCDHGA9, PCDHGA7, PCDHGA6, PCDHGA5, PCDHGA3, PCDHGA2, PCDHA3, PCDHA11, PCDHA10, PCDH15, PCDHAC1, PCDH |
| homotypic cell-cell adhesion | biological process | MEGF10, CXADR, PTPRU, PLPP3, MEGF11 |
| horizontal cell localization | biological process | LHX1 |
| hormone biosynthetic process | biological process | CYP17A1, HFE, TPO, FDX1, CHST9, DIO2, DUOX2, DIO3, DUOX1, TG, CHST8 |
| hormone catabolic process | biological process | ACE, ECE1, IDE |
| hormone metabolic process | biological process | NR5A1, LEP, PTPN11, ALDH9A1, FOXA1, PRLHR, WNT4, SELENOM, CRHBP, GHRHR, GHR, SAFB, DDO, KLK6 |
| hormone secretion | biological process | ADM, LTBP4 |
| hormone transport | biological process | SLC22A9 |
| hormone-mediated apoptotic signaling pathway | biological process | METTL21C, CRH, SSTR3, SST |
| hormone-mediated signaling pathway | biological process | NR5A2, LHCGR, FSHR, NR5A1, GHRL, TRH, PTPN11, NR1D2, JAK2, RARB, ADIPOR1, LGR4, ASIP, PPARD, RXFP1, GHSR, ADIPOR2, TSHB, CRHBP, GCGR, LATS2, GTF2H1, LATS1, NR1D1, CRHR1, CRHR2, CGB1, TSHR, UCN3, OSTN, UCN2, LGR5, RARG, PPARA, THRA, CGB3, RARA |
| host-mediated regulation of intestinal microbiota composition | biological process | NAPEPLD, LRRC19 |
| Hsp90 deacetylation | biological process | HDAC6 |
| humoral immune response | biological process | TNF, IFNG, IL6, BCL2, IFNA1, LTF, PDCD1, ST6GAL1, FOXJ1, AIRE, GPR183, CD83, IL7, TRAF3IP2, IFNA8, NOTCH1, GATA3, MEF2C, IFNA10, CCR6, TREM1, PAX5, GPI, TFE3, RBPJ, POU2F2, ALOX5, MS4A1, YTHDF2, TREM2, MNX1, BST1, TNFRSF21, IFNA2, IFNA14, CD28, TFEB, EBI3, IFNW1, LTA, POU2AF1, CCL2, PSMB10 |
| humoral immune response mediated by circulating immunoglobulin | biological process | HLA-DRB1, HLA-DQB1, BCL3, CD81, EXO1, ZP3 |
| hyaloid vascular plexus regression | biological process | OPN5, SLC17A6, TH, NINJ1, DRD2, SLC6A3, OPN4 |
| hyaluronan biosynthetic process | biological process | IL1B, CEMIP, HAS2, HAS3, ABCC5, HAS1 |
| hyaluronan catabolic process | biological process | TGFB1, CD44, HEXA, HEXB, CEMIP, HMMR, GUSB, SLC9A1, LYVE1, HYAL3, CEMIP2, CHP1, HYAL2, FGF2, STAB2 |
| hyaluronan metabolic process | biological process | AKT1, HGF, IL15, ITIH2, HAS2, ITIH6, ITIH4, ITIH5, ITIH3 |
| hydrogen ion transmembrane transport | biological process | COA6, COX10, CYB5A, MT-CO1, MT-CO3, MT-CYB, ATP6V1B1, ATP2A2, ATP5PO, ATP6V1D, NDUFA4, COX7A2L, ATP6V1G1, ATP5F1B, COX7C, ATP6V1B2, DMAC2L, COX5A, ATP5MC3, SLC15A4, COX7B2, NMES1, COX7A2, COX7B, SLC36A1, ATP6V1E1, UCP3, SLC15A2, SLC9C1, OTOP3, HVCN1, SLC17A5, SLC9A2, ATP6V0E1, ATP6V1G2, ATP5MC1, COX6A1, SLC9A1, ATP6V1A, ATP2C1, ATP5MC2, NNT, SLC9A7, SLC2A10, COX6C, ATP1A4, SLC36A2, TMCO3, SLC9A9, UCP1, ATP6V1G3, ATP1A3, ATP5MF, SLC36A3, COX6B1, ATP1A2, SLC9B2, COX8A, CLCN3, SLC25A3, SLC9C2, ATP6V0E2, MT-CO2, COX4I1, UCP2, SLC25A14, ATP6V1C1, SURF1, SLC2A8, ATP6V1H, SLC33A1, ATP6V0D1, SLC4A11, ATP2A3, ATP6V0B, ATP6V0A4, ATP6AP1, SLC9A6, NDUFA4L2, ATP1A1, CLCN4, ATP6V1F, COX6A2, TCIRG1, COX8C, ATP4A, COX7A1, OTOP1, ATP6V1E2, SLC2A6, ATP2A1, ATP6V0C, ATP2C2, MFSD3, ATP6V1C2, SLC15A1, CLCN5, SLC4A10, ATP6V0A1 |
| hydrogen peroxide biosynthetic process | biological process | SOD1, CYP1A1, CYP1A2, CYBB, CYBA, DUOX2, DUOX1 |
| hydrogen peroxide catabolic process | biological process | GPX1, CAT, LPO, PRDX2, PRDX1, TPO, HBG2, PXDNL, PRDX6, EPX, GPX3, HBD, HBB, HBZ, PRDX3, PRDX5, DUOX2, MPO, HBQ1, PXDN, HBA1, DUOX1 |
| hydrogen peroxide metabolic process | biological process | PARK7, NOX1, DUOXA2, DUOXA1 |
| hydrogen peroxide transmembrane transport | biological process | AQP11 |
| hydrogen sulfide biosynthetic process | biological process | CBS, CTH, MPST |
| hydrogen sulfide metabolic process | biological process | ETHE1, SQOR |
| hydroxylysine biosynthetic process | biological process | PLOD1, PLOD2, PLOD3 |
| hydroxyproline transport | biological process | SLC1A4 |
| hypermethylation of CpG island | biological process | GSK3B, SPI1 |
| hyperosmotic response | biological process | SLC12A2, HNMT, AQP1, SST, PKN1, TLR3, PDPK1, ICOSLG |
| hyperosmotic salinity response | biological process | TACR3, OXT, MT-CYB, AVP, CLDN1 |
| hypochlorous acid biosynthetic process | biological process | MPO |
| hypoglossal nerve morphogenesis | biological process | ADARB1 |
| hypomethylation of CpG island | biological process | PIK3CA, ZMPSTE24, NIBAN2 |
| hypophysis morphogenesis | biological process | PROP1 |
| hypothalamus cell differentiation | biological process | PROP1, OTP, POU3F2, HAP1 |
| hypothalamus cell migration | biological process | FOXB1 |
| hypothalamus development | biological process | SRD5A2, BAX, ESR2, SOX3, NR0B1, SRD5A1, CRH, ETS1, UQCRQ, NCOA1, RAX, RAB3GAP1, GSX1 |
| hypothalamus gonadotrophin-releasing hormone neuron development | biological process | UBB |
| hypotonic response | biological process | ITGA2, SLC12A5 |
| hypoxanthine biosynthetic process | biological process | PRPS1, ADA |
| hypoxanthine metabolic process | biological process | HPRT1 |
| hypoxanthine salvage | biological process | CECR1, HPRT1, ADA |
| hypoxanthine transport | biological process | SLC29A2 |
| hypoxia-inducible factor-1alpha signaling pathway | biological process | HIF1A, PDK3, CYBB, PDK1 |
| I-kappaB kinase/NF-kappaB signaling | biological process | TNF, TNFRSF1A, TLR4, TBK1, TBKBP1, BCL10, SNIP1, LY96, MAP3K7, BCL3, RPS27A, FAIM, IRAK2, ROCK2, TIAF1, TAB1, RELA, ROCK1, NKIRAS1, NFKBIA, TANK, NFKB2, REL, BIRC2, NKIRAS2, HACD3, IKBKG, SHARPIN, TAB2, IRAK1BP1, RIPK2, TIFAB, TICAM2, TIFA, RBCK1, TRAF6, UBC, UBA52, TAB3, BTK, IKBKB, AVPR2, TRADD, MAP3K14, CARD9, TLR9, RIPK3, TNIP2, TLR7, TLR3, UBB, RELB, RNF31, TRAF2, CARD11, ZNF675, TICAM1 |
| I-kappaB phosphorylation | biological process | TLR4, TLR2, PRDX4, MAP3K7, DAB2IP, IKBKE, ERC1, IKBKB, TLR9, TLR7, TLR3 |
| icosanoid biosynthetic process | biological process | CYP4A11, CYP2C8, PLA2G4A, FADS1, CYP2C9 |
| icosanoid metabolic process | biological process | CYP2J2, CYP4F3, CYP4F8, CYP4F22, PTGIS, PLA2G4A, TBXAS1, CYP4F2, CYP2S1 |
| IDP catabolic process | biological process | NUDT9, NUDT16 |
| IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor | biological process | FCGRT |
| immature B cell differentiation | biological process | KIT, IRF2BP2, FNIP1, SYVN1 |
| immature T cell proliferation in thymus | biological process | WNT4 |
| immune complex clearance by monocytes and macrophages | biological process | FCGR2B |
| immune complex formation | biological process | TREX1 |
| immune response | biological process | TNF, IFNG, IL1B, HLA-DRB1, HLA-DPB1, IL4, IL6, CXCL8, LIF, RAG1, IL1RN, TNFRSF1A, TNFRSF1B, IL10, FAS, IL12A, TNFSF10, IL18, IL23A, HLA-B, HLA-DQB1, HLA-A, HLA-E, KIR2DS2, FASLG, ATP6V0A2, TLR4, TLR2, SEMA7A, C3, IL1A, HLA-DRA, CYP11B1, B2M, TGFBR3, HFE, IL2RA, HLA-DQA1, IL5, IGF1R, CCL5, HLA-G, IL2, C1QBP, IL17A, IL21, FCGR3A, CCR5, DPP8, AZGP1, IL1R2, CD8A, SLPI, HLA-C, CX3CL1, TNFRSF25, CCL16, TCF7, CCL20, ACKR4, TNFSF15, VPREB1, IL15, CEBPG, CXCR4, SCAP, AIRE, CD74, CCR1, GPR183, CTSK, CTSW, CCL8, MAP4K2, IFI44L, IFI44, PRELID1, IL7, CD79B, EXOSC9, ENPP2, CXCL11, LY75, PRKRA, IL1R1, XBP1, CCL1, TNFAIP1, CCL14, TNFSF12, CCL3, C6, XCR1, CTSC, NCR3, CNIH1, LY86, FTH1, BMPR1A, CCL11, LTB, IL1F10, PNP, IL13, SERPINB9, CXCL6, COLEC12, GTPBP1, IFI6, CTLA4, FCGR2B, NOTCH1, GEM, MADCAM1, NKX2-3, SEMA4D, IL1RAP, CD274, HLA-DQA2, THBS1, HLA-DMB, CEACAM8, CXCR5, CD86, ZAP70, IKBKE, CCL22, DEFB4A, IL18RAP, PF4, CTSG, IL3, ENPP1, ACKR3, DEFB1, TLR1, TLR10, KAAG1, C1QC, HLA-DOA, ETS1, CXCR2, GBP2, TNFRSF4, CCR6, IL36RN, |
| immune response in brain or nervous system | biological process | TREX1 |
| immune response in nasopharyngeal-associated lymphoid tissue | biological process | BPIFA1 |
| immune response to tumor cell | biological process | PRF1 |
| immune response-activating cell surface receptor signaling pathway | biological process | NCR3, MICB |
| immune response-activating signal transduction | biological process | ZC3H12A |
| immune response-inhibiting cell surface receptor signaling pathway | biological process | HLA-G |
| immune response-inhibiting signal transduction | biological process | IL20RB, CD33 |
| immune response-regulating cell surface receptor signaling pathway | biological process | BTLA, LYN, FGR, FPR2, CD40 |
| immune response-regulating signaling pathway | biological process | LAT2, CTSH |
| immune system development | biological process | BCL2, RO60, CACNA1C, GATA3, SMAD3 |
| immune system process | biological process | HLA-DRB1, HLA-DPB1, CASP4, IL23A, HLA-B, HLA-DQB1, HLA-A, HLA-E, AXL, S100A12, TLR4, TLR2, C3, HLA-DRA, CLU, BAG6, B2M, IL2RA, HLA-DQA1, LTF, CD79A, SRC, MIF, CD46, HLA-G, IL2, C1QBP, PDCD1, MEFV, CLEC7A, CAMK4, CD8A, SLPI, S100A9, CSF1, HLA-C, PSTPIP1, C1QB, MATR3, FGL1, CLEC6A, FBXO38, DDX1, OPTN, ERAP1, TBK1, DDX3X, JAK2, PSMA1, ADARB1, G3BP1, ERAP2, IDO2, LACC1, ITCH, YTHDF1, IFIH1, TRIM4, POLR3F, TBKBP1, TRIM13, CD74, CD55, XRCC5, GPR183, USP14, OLR1, MAP4K2, ZC3H12A, PSPC1, DHX36, LGALS9, BCL10, CFD, OAS1, SFPQ, CD79B, BCL6, BST2, TRIM25, NLRX1, DTX3L, LGR4, LY96, LILRA5, EOMES, IFI30, CD1C, ADSS2, IRAK1, ADAR, CD81, DAB2IP, APOBEC3F, ISG20, ALPK1, MYD88, LAMP3, PPP6C, HMGB3, AKAP8, C6, PRKD1, SEC14L1, DDX21, LYAR, NCR3, KCNN4, LY86, ANXA1, IDO1, C4BPB, SYK, TAP1, TRAF3, ZC3HAV1, BTLA, FCAMR, PLD4, GBP5, ZCCHC3, TTC4, C5, CFH, C1S, CTPS1, PSMB8, MAP3K8, THEMIS2, SUSD4, CD300LG, IL34, NLRP9, HAVCR2, DHX58, DCLRE1C, LAT2, POLR3K, IFI6, CTLA4, IRF9, TNFRSF17, TAP2, ITK, OASL, PARP14, CLEC4C, RSAD2, ECSIT, |
| immunoglobulin biosynthetic process | biological process | GALNT2, PTPRC |
| immunoglobulin biosynthetic process involved in immune response | biological process | TREX1 |
| immunoglobulin heavy chain V-D-J recombination | biological process | POLB |
| immunoglobulin mediated immune response | biological process | IL13RA2, CD74, BCL10, FCGR2B, PRKCD, IRF7, FCER1G, TCIRG1, CD19, IL4R, INPP5D |
| immunoglobulin production | biological process | FAS, VPREB1, DNAJB9, ATAD5, CD86, PHB2, PRKDC, IL7R, ITM2A, TCIRG1, CARD11, VPREB3 |
| immunoglobulin production involved in immunoglobulin mediated immune response | biological process | HLA-DRB1, HLA-DQB1, FGL2 |
| immunoglobulin secretion | biological process | TRAF3IP2, TNFSF13B, POU2F2 |
| immunoglobulin secretion involved in immune response | biological process | POU2F2 |
| immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor | biological process | PIGR, RAB17 |
| immunoglobulin V(D)J recombination | biological process | LIG4, PRKDC, XRCC4 |
| immunological synapse formation | biological process | PRF1, CD81, NCK2, EPHB1, DLG1, MSN, DOCK8, CCL19, CD6, CORO1A, DOCK2, CCL21 |
| IMP biosynthetic process | biological process | AMPD2, AMPD3 |
| IMP metabolic process | biological process | ADSS2, ADSS1, HPRT1, NT5C2 |
| IMP salvage | biological process | AMPD2, HPRT1, AMPD3 |
| import across plasma membrane | biological process | SLC6A6, SLC9A3R1, SLC39A14 |
| import into cell | biological process | ITGA4, TREM2 |
| import into nucleus | biological process | RAB18, HNRNPA1, SNRPE, GEMIN6, SNRPB, GEMIN5, DDX20, GEMIN4, SNRPD1, BACH2, SNRPD2, HTATIP2, SNRPG, GEMIN8, SMN1, SNUPN, SNRPF, GEMIN7 |
| in utero embryonic development | biological process | TGFB3, VEGFA, NOS3, LIG4, SOX10, CCNB2, APOB, CCNB1, ERCC2, FGFR2, UBE2B, HSF1, NODAL, ARNT2, ITGB1, ENO1, FGFR1, EDNRA, CTNNB1, HSD17B2, GJA1, NR2F2, EMX1, CHD7, TPM1, PKD1, SIN3A, PYGO2, NBN, MT-ND4, MSH2, ETV2, XRCC2, GLI3, WDR19, ZFPM2, YBX3, BTF3, MYH10, KEAP1, CIR1, MIB1, EIF2S2, NSUN2, PTPRR, RNASEH2B, ALS2, TANC2, ZFAND5, ACVR1B, SSR2, SMAD4, NPAT, MAN2A1, TCTN1, TENT5C, FLVCR1, BCL2L11, PTH1R, ZNF568, RTCB, C6, PCGF2, TIE1, SOX18, ELL, OCRL, ACVR1, HES1, RBBP6, EGFL8, ETNK2, ZMIZ1, B9D1, BMPR1A, WNT7B, ASCL2, LMX1B, YBX1, TAB1, WNT9B, MAFG, SYF2, NOTCH1, WNT3A, SP3, ENDOG, AMOT, UNK, MBNL1, POLG2, PRDM1, GATA3, MSX1, GJB3, PSPH, TMED2, HM13, ZNF335, MAFF, CMIP, SMO, FUT8, SALL4, ANGPT1, UBR3, CELF4, EPB41L5, KIDINS220, EIF4E2, GNA12, C2CD3, ANKRD11, WDTC1, CHTOP, CERT1, SLC30A1, CPT2, TWIST1, INPP5K, RRN3, TRAF6, SEC24D, JUNB, NMT1, SOX6, TGFBR1, ATP7A, APBA2, ADA, ATP11A, SMAD2, NXN, PALB2, FLCN, TMEM100, EPN1, TBX3, ADCY9, INPP5B, APBA1, DSC3, PRMT1, MBD3, GABPA, BCL2L1, PLOD3, PDGFRB, SRF, ADD1, T |
| inactivation of MAPK activity | biological process | DUSP6, PPP2CA, DUSP8, SPRED1, DUSP21, DUSP14, DUSP5, GPS2, PP2D1, DUSP18, DUSP1, DUSP3, DUSP7, GPS1, DUSP9, DUSP16, PPP2R1A, RGS4, DUSP2, CAV1, LAX1, DUSP10 |
| inactivation of MAPK activity involved in osmosensory signaling pathway | biological process | MBIP |
| inactivation of MAPKK activity | biological process | IGF1R, EPHB2 |
| inactivation of X chromosome by DNA methylation | biological process | SMCHD1 |
| inactivation of X chromosome by genetic imprinting | biological process | PCGF3, PCGF5 |
| inactivation of X chromosome by heterochromatin assembly | biological process | SMCHD1 |
| inclusion body assembly | biological process | PSAP |
| indolalkylamine biosynthetic process | biological process | DDC, TPH1, TPH2, AANAT |
| indole metabolic process | biological process | SLC34A1 |
| induction by virus of host autophagy | biological process | PHB2 |
| induction by virus of host cell-cell fusion | biological process | CD4 |
| induction of negative chemotaxis | biological process | SLIT2 |
| induction of positive chemotaxis | biological process | CXCL8, VEGFA, CREB3, VEGFC, SCG2, IL16, AZU1, VEGFB, NTF3, CXCL12, FGF10, AGER |
| induction of synaptic plasticity by chemical substance | biological process | MAP1B |
| induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration | biological process | CNR1, CDK5, CACNA1D, CACNB2 |
| inductive cell-cell signaling | biological process | SALL1 |
| inferior colliculus development | biological process | FOXB1 |
| inferior endocardial cushion morphogenesis | biological process | TGFBR2 |
| inflammatory cell apoptotic process | biological process | IFNG, FAS, FASLG, ZMPSTE24 |
| inflammatory response | biological process | TGFB1, TNF, IL1B, IL6, CXCL8, TNFRSF1A, TNFRSF1B, IL10, PTGS1, FAS, PTGS2, CASP4, IL18, IL23A, AXL, AKT1, S100A12, NFE2L2, TLR4, TLR2, SEMA7A, C3, IL1A, CRP, LYZ, PARK7, IL2RA, IL5, KIT, CCL5, MIF, IL17A, MEFV, F2R, EPHX2, CCR5, CLEC7A, PROK2, CYP26B1, AIF1, CAMK4, ECM1, SERPINA3, S100A9, CSF1, TAC1, TNFRSF25, CCL16, PJA2, PSTPIP1, HDAC4, CCL20, HNRNPA0, TBK1, IL15, CXCR4, LACC1, ITCH, TNIP3, NOX1, TPST1, CCR1, OLR1, CCL8, ZC3H12A, LGALS9, APOL3, BDKRB2, BCL6, REG3A, CD47, NFX1, PLA2G4C, LY96, AP3B1, CXCL11, KDM6B, LY75, CYBB, TMIGD3, IL1R1, CCL1, CCL14, DAB2IP, MYD88, IRAK2, CCL3, SPP1, HRH1, XCR1, TNFAIP6, PRKD1, CAMK1D, HDAC9, NCR3, LY86, ORM1, ANXA1, IDO1, CCL11, IL1F10, PLD4, GBP5, IL17C, C5, IL13, CHI3L1, LIPA, CXCL6, THEMIS2, IL34, NLRP9, IL17D, HAVCR2, LIAS, FCGR2B, NFATC3, AFAP1L2, IL1RAP, CRH, THBS1, CYBA, PTGER2, RELA, PRKCQ, NAIP, REG3G, PLGRKT, STARD7, CCL22, IL18RAP, PF4, CRHBP, AGTR1, PTGER1, MAP2K3, TIRAP, TLR1, IL23R, TLR10, NFKBIZ, ODAM, HMGB1, SELP, ITGB6, CXCR2, FPR3, TNFRSF4, UCN, TAC4, I |
| inflammatory response to antigenic stimulus | biological process | HLA-DRB1, IL2RA, CYSLTR1, KDM6B, IL20RB, IL1F10, RASGRP1, NOTCH1, HMGB1, IL36RN, IL25, RBPJ, PNMA1, IL36G, IL5RA, TREX1 |
| inflammatory response to wounding | biological process | WDR83 |
| ingression involved in gastrulation with mouth forming second | biological process | CRB2 |
| inhibition of cysteine-type endopeptidase activity | biological process | CAST, CARD18, CARD16, CARD8, CST7 |
| inhibition of cysteine-type endopeptidase activity involved in apoptotic process | biological process | BIRC5, BCL2L12, XIAP, BIRC7, BIRC2, NOL3 |
| inhibition of neuroepithelial cell differentiation | biological process | NODAL |
| inhibitory chemical synaptic transmission | biological process | PTCHD1 |
| inhibitory postsynaptic potential | biological process | CX3CL1, GABRB3, GLRA1, CHRNA4, NPAS4, ADORA2A, GRIK2, DRD4, INSYN2A |
| inhibitory synapse assembly | biological process | GABRA2, CBLN4, NLGN2, GABRG2, GABRB3, GABRB2, LGI2, GABRA1, PLXNB1, NPAS4 |
| initiation of primordial ovarian follicle growth | biological process | FOXO3, GAS2 |
| innate immune response | biological process | CASP4, IL23A, IFNA1, HLA-E, TYK2, AXL, KIR2DS2, S100A12, TLR4, TLR2, C3, APP, CLU, B2M, YES1, SRC, MIF, CD46, C1QBP, MEFV, PPARG, DEFB106A, CLEC7A, DEFB126, DEFB129, SLPI, S100A9, CSF1, SAA1, TAC1, MALT1, PJA2, PSTPIP1, C1QB, MATR3, CLEC6A, DDX1, OPTN, TBK1, TRIM17, SIRPB1, DDX3X, JAK2, ADARB1, G3BP1, LACC1, ITCH, IFIH1, TRIM4, POLR3F, TBKBP1, TRIM13, CD55, XRCC5, USP14, MAP4K2, WFDC9, PSPC1, DHX36, BCL10, CFD, OAS1, SFPQ, BST2, TRIM25, NLRX1, DTX3L, LGR4, WFDC10A, LY96, LILRA5, CYBB, IRAK1, ADAR, DAB2IP, TREML1, APOBEC3F, TRIM58, ISG20, TRIM11, ALPK1, MYD88, FBXO9, PPP6C, HMGB3, AKAP8, C6, CAMP, CAPZA1, PRKD1, TKFC, SEC14L1, DDX21, LYAR, LY86, ANXA1, C4BPB, SYK, TRAF3, TRIM68, ZC3HAV1, PLD4, SRPK1, TRIM15, ZCCHC3, TTC4, C5, CFH, C1S, KIR2DS4, SRPK2, COLEC12, SUSD4, IL34, NLRP9, WFDC13, HAVCR2, DHX58, POLR3K, NPY, IFI6, OASL, PARP14, CLEC4C, RSAD2, ECSIT, NOD2, IL1RAP, PRDM1, IFIT1, ITGAM, XRCC6, CYBA, GATA3, KLRC2, RELA, TRIM32, NAIP, FADD, NONO, SARM1, IFNL1, RNF135, SIRT2, OTULIN, COLEC11, TRIM8, CD209, MA |
| innate immune response activating cell surface receptor signaling pathway | biological process | LILRA2 |
| innate immune response in mucosa | biological process | IL4, LTF, NOS2, H2BC21, CAMP, RPL39, DEFA3, H2BC12, DEFB1, DEFA5, BPIFB1, PLA2G1B, RNASE3, DEFA4, DEFA1, H2BC10 |
| innate immune response-activating signal transduction | biological process | HCK |
| innate vocalization behavior | biological process | FOXP2 |
| inner cell mass cell differentiation | biological process | HNF1B, CTR9, TET1, NLE1 |
| inner cell mass cell fate commitment | biological process | LATS1 |
| inner cell mass cell proliferation | biological process | BRCA2, GINS1, PRPF19, SBDS, PELO, COPS2, SALL4, ZPR1, PALB2, NCAPG2 |
| inner cell mass cellular morphogenesis | biological process | LATS1 |
| inner dynein arm assembly | biological process | CCDC103, DNAH1, TEKT2, LRRC6, DNAAF1, WDR63, DNAAF4, ZMYND10, CFAP73, CFAP100, CCDC40, DNAAF5 |
| inner ear auditory receptor cell differentiation | biological process | USH1C, MYO6, MCOLN3, JAG1, MYO7A |
| inner ear development | biological process | TGFB1, TGFB3, SOX2, PTPN11, SHH, C1QB, GLI3, ROR1, ANP32B, PHOX2B, LHX3, LIN7A, NEUROG1, COL2A1, CYTL1, HPCA, FREM2, MAF, STOX1, NEUROD1, TGFB2, CDKN1B, TIFAB, ADGRV1, SIX1, PLPPR4, C1QTNF5, PDGFRB, BMP2, CCM2, DLL1, GJB6, CXCL14, BMPER, LGR5, PROX1, JAG1, MYO7A, LRP10, ESRRB, MPV17, CEBPD, PCDH15 |
| inner ear morphogenesis | biological process | FGFR2, FGFR1, OTX1, FGF8, CHD7, FGF9, MYO15A, COL11A1, ATP6V1B1, USH1G, EPHB2, BCR, ABR, FRZB, NEUROG1, COL2A1, WNT3A, FZD3, NTN1, GATA3, PAX8, USH1C, ALDH1A3, PRRX1, CHRNA10, CELSR1, MYO6, TFAP2A, SLITRK6, ATP8A2, FOXG1, DLX6, TIFAB, INSIG1, GATA2, FOXI1, SIX1, SPRY2, DLX5, SIX4, EYA1, GBX2, FZD6, KCNQ4, NR4A3, OTOP1, ROR2, MYO7A, TMIE, SOBP, FGF10, ITGA8, INSIG2 |
| inner ear receptor cell development | biological process | FZD2, GABRB3, GABRA5, GABRB2, VANGL2, NAGLU, ATP8B1 |
| inner ear receptor cell differentiation | biological process | BMP4, USH1G, GSDME, USH2A, FGF20, MYO7A |
| inner ear receptor cell stereocilium organization | biological process | IFT88, USH1G, HES1, SDC4, USH1C, SCRIB, TRIP11, VANGL2, ADGRV1, CTHRC1, MYO7A, WHRN, CDH23 |
| inner medullary collecting duct development | biological process | AKR1B1, WNT7B, DACT2 |
| inner mitochondrial membrane organization | biological process | BAX, MAIP1, DNAJC11, SAMM50, MTX2, CHCHD6, OPA1, TMEM11, APOO, MTX3, FAM92A, IMMT, MICOS10, MTX1, MICOS13, CHCHD3 |
| innervation | biological process | NTRK1, ISL1, ADARB1, NTF4, GABRB3, GABRA5, GABRB2, SLITRK6, RNF165, UNC13B, POU4F1, RET, LRIG2, SULF1, PRKCG, UNC13A, SULF2, FBXO45, LRIG1 |
| inorganic anion import across plasma membrane | biological process | SLC12A2 |
| inorganic anion transport | biological process | SLC26A4, PHLPP2, SLC4A7, LRRC28, LRRC8D, SLC4A4, BEST3, SLC39A8, LRRC8C, GPR89A, GPR89B, SLC4A2, LRRC8B, PHLPP1, SLC22A11, SLC4A3, SLC22A8, SLC39A14, SLC4A9, CCT8L2, VDAC2 |
| inorganic cation import across plasma membrane | biological process | SLC12A2 |
| inorganic cation transmembrane transport | biological process | PKD2, PKD2L1, ABCC9, CACNA1H, KCNJ8, TRPM4, ABCC8 |
| inosine biosynthetic process | biological process | CECR1, ADAL, ADA |
| inosine catabolic process | biological process | PNP |
| inosine transport | biological process | SLC28A2 |
| inositol biosynthetic process | biological process | IMPA1, ISYNA1, IMPA2 |
| inositol lipid-mediated signaling | biological process | PLD1, ADAP2, PLD2, TNFAIP8L3 |
| inositol metabolic process | biological process | PPIP5K1, IMPA1, MECP2, PPIP5K2, IMPA2, ITPKA |
| inositol phosphate biosynthetic process | biological process | ITPKB, IP6K3, PPIP5K2, FGF2, ITPKA, IP6K2, IPPK, IPMK |
| inositol phosphate catabolic process | biological process | NTSR1 |
| inositol phosphate dephosphorylation | biological process | PTEN, SYNJ1, IMPA1, OCRL, BPNT2, INPP5A, SYNJ2, INPP5K, IMPA2, INPP5B, INPP1, INPP5E, MTMR7 |
| inositol phosphate metabolic process | biological process | PTEN, PLCZ1, PPIP5K1, INPP4B, SYNJ1, PLCH2, IMPA1, NUDT4, OCRL, INPP5A, PLD4, ITPKB, IP6K3, PLCB2, PLCB3, PLCD1, INPP4A, PLCE1, MINPP1, CALM1, ISYNA1, PPIP5K2, ITPK1, IMPA2, INPP5B, INPP1, ITPKA, IP6K2, NUDT3, PLCD4, IPPK, PLCG2, PLCH1, IPMK, INPP5D |
| inositol phosphate-mediated signaling | biological process | HRH1, INPP5A, ITPR3, PLCE1, ITPR1, NMUR2, NMUR1, ITPR2, EDN1, EDN3 |
| inositol phosphorylation | biological process | ITPK1, IPPK |
| inositol trisphosphate biosynthetic process | biological process | PLCH2, SCP2, PLCL1, PLCB2, PLCB3, PLCD1, PLCE1, PTAFR, PLCD4, PLCG2, PLCH1, PLCL2 |
| inositol trisphosphate metabolic process | biological process | ITPKB, ITPK1, IPMK |
| insecticide metabolic process | biological process | CYP1A1, STAR |
| insemination | biological process | SEMG1, TAC1, DDO |
| insulin catabolic process | biological process | IDE, CELA2A, CEACAM1 |
| insulin metabolic process | biological process | IDE, ERN1 |
| insulin processing | biological process | PCSK2, ERO1B, CPE |
| insulin receptor internalization | biological process | CEACAM1, CAV1 |
| insulin receptor recycling | biological process | SORL1 |
| insulin receptor signaling pathway | biological process | IGF2, AKT1, ATP6V0A2, INSR, IGF1R, SOS1, FOXO1, ATP6V1B1, PDK4, STXBP4, SORBS1, ATP6V1D, ATP6V1G1, ATP6V1B2, ZNF106, BAIAP2, PIK3C2A, PIK3R1, SHC1, IGFBP1, PTPRA, GRB10, EIF4EBP2, PTPN2, ATP6V1E1, PHIP, AP3S1, IDE, ATP6V0E1, ATP6V1G2, ATP6V1A, BCAR1, NAMPT, IRS2, IRS1, EIF4EBP1, CAV2, GRB7, ATP6V1G3, GPLD1, RHOQ, APC, CSRP3, GRB2, GAB1, ATP6V0E2, PIK3R3, FOXC2, ATP6V1C1, SLC2A8, ATP6V1H, PTPN1, SMARCC1, ATP6V0D1, ATP6V0B, ATP6V0A4, SREBF1, IRS4, ATP6AP1, BCAR3, FOXO4, ATP6V1F, TCIRG1, RARRES2, KL, APPL1, PIK3R2, FOXO3, ATP6V1E2, SOGA1, INS, INSRR, ATP6V0C, AKT2, PDK2, SLC39A14, ATP6V1C2, SH2B2, RPE65, ATP6V0A1 |
| insulin receptor signaling pathway via phosphatidylinositol 3-kinase | biological process | IGF2, PIK3CA, C2CD5, FER |
| insulin secretion | biological process | IL1RN, HNF1A, HNF1B, LEP, SNX19, RIMS2, FAM3B, CPLX1, ANXA1, GPR119, ACVR2B, MYO5A, PDX1, SLC30A8, NEUROD1, ILDR2, CYB5R4, FKBP1B, STXBP3, SMAD2, FFAR1, VGF, CAMK2G, GAL, CPLX3, RAPGEF4 |
| insulin secretion involved in cellular response to glucose stimulus | biological process | RAF1, RAB11FIP2, RAB11FIP5, SELENOT, RAB11B, PTPRN2, CCDC186 |
| insulin-like growth factor receptor signaling pathway | biological process | AKT1, IGF1, IGF1R, IGF2R, PIK3R1, IRS1, GHR, GIGYF2, TSC2, EIF2AK3 |
| integrin activation | biological process | FN1, CX3CL1, FERMT2, ITGB1BP1, FERMT3, COL16A1, TLN1, CXCL12, MZB1 |
| integrin biosynthetic process | biological process | COL5A1 |
| integrin-mediated signaling pathway | biological process | SEMA7A, ITGB1, ITGA5, ADAMTS1, ITGAV, SRC, ITGA4, ITGA6, PTPN11, CCN2, ERBIN, ITGAE, FERMT2, CD47, MPIG6B, ITGA2B, ITGB5, PTN, VAV3, ADAM11, PTK2, PRKD1, COL3A1, PLEK, SYK, DAB2, FERMT1, ITGA10, BCAR1, MADCAM1, RCC2, ITGAM, FBLN1, DST, ANGPTL3, ISG15, ITGA2, ITGB6, TEC, PRAM1, FUT8, NEDD9, ITGB1BP1, APOA1, ITGB3, ITGB4, CDH17, TYROBP, FYB2, FYB1, ABL1, ADAM9, DOCK1, ITGBL1, NME2, ITGB8, ITGAX, ITGB7, ITGB2, FGR, ILK, CEACAM1, FCER1G, ITGA9, PLPP3, HCK, CCM2, LAT, THY1, MYH9, ITGA7, LAMA3, FERMT3, NRP1, LAMA5, VAV1, COL16A1, ITGAD, ADAMTS13, TSPAN32, TLN1, ITGAL, ITGA3, PTK2B, ITGA11, ITGA8, ZYX |
| intein-mediated protein splicing | biological process | SHH, IHH |
| inter-male aggressive behavior | biological process | KIRREL3 |
| interaction with symbiont | biological process | GPX1, PLG, DDB1 |
| interferon-alpha production | biological process | IRF7, TREX1 |
| interferon-beta production | biological process | STING1, IRF7, TRIM56 |
| interferon-gamma biosynthetic process | biological process | IL18 |
| interferon-gamma production | biological process | TLR4, EOMES, ITK, IL18RAP, AVPR2, SPN, IL12RB2 |
| interferon-gamma secretion | biological process | GATA3, BTN3A1, ISG15, BTN3A2, VTCN1, TCIRG1 |
| interferon-gamma-mediated signaling pathway | biological process | IFNG, HLA-DRB1, HLA-DPB1, ICAM1, CD44, HLA-B, HLA-DQB1, HLA-A, HLA-E, STAT1, HLA-DRA, B2M, HLA-DQA1, HLA-G, NCAM1, HLA-C, CAMK2B, CAMK2D, JAK2, OAS1, VCAM1, TRIM25, IFI30, IFNGR1, TRIM68, IFNGR2, IRF9, OASL, HLA-DQA2, TRIM8, IRF6, GBP2, IRF5, JAK1, SP100, TRIM38, GBP1, HLA-DPA1, PML, PRKCD, MT2A, IRF2, TRIM62, IRF1, IRF8, IRF7, MID1, CIITA, HCK, TRIM21, PTAFR, CAMK2G, IRF3, CAMK2A, OAS2, HLA-F, TRIM5, TP53, TRIM22, TRIM31 |
| interkinetic nuclear migration | biological process | PCM1, HOOK3, CEP120, DOCK7, KIF1A |
| interleukin-1 alpha secretion | biological process | S100A13 |
| interleukin-1 beta production | biological process | IL1B, CASP1, NLRP3, MR1, PYCARD, SUCNR1 |
| interleukin-1 beta secretion | biological process | TLR4, GBP5, AIM2, TMEM106A, TLR6, CD36 |
| interleukin-1 secretion | biological process | NLRP3 |
| interleukin-1-mediated signaling pathway | biological process | MAPK3, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, PSMD14, PSMD7, PELI1, BTRC, MAP3K7, IL1R1, PSMB6, IRAK1, UBE2N, RPS27A, MYD88, IRAK2, PSMD10, PSMD8, PSMC5, EGR1, PSMB4, PSME1, CUL1, PSMB8, MAP3K8, PSMD4, TAB1, PSMC3, PSMA6, NOD2, IL1RAP, RELA, PELI2, IRAK3, NFKBIA, SQSTM1, MAP3K3, IKBKG, UBE2V1, TOLLIP, TAB2, PSMD12, PSMB9, PSMC4, PSMD9, RIPK2, PSMA4, PSMD2, TRAF6, UBC, UBA52, PSMD5, PELI3, TAB3, PSMF1, PSMB3, IKBKB, PSMD3, RPS6KA5, PSMC1, RBX1, TNIP2, RPS6KA4, UBB, IL1RL2, NOD1, ST18, IRAK4, PSMD13, PSMB10 |
| interleukin-10 production | biological process | TLR2, CD46, PRKCD |
| interleukin-10 secretion | biological process | ISG15 |
| interleukin-11-mediated signaling pathway | biological process | IL6ST, IL11RA |
| interleukin-12 production | biological process | PRKCD |
| interleukin-12 secretion | biological process | CCR7 |
| interleukin-12-mediated signaling pathway | biological process | HNRNPF, JAK2, RPLP0, AIP, P4HB, RALA, TCP1, PITPNA, CNN2, HNRNPA2B1, CAPZA1, IL12RB1, SERPINB2, ARF1, LMNB1, TALDO1, GSTO1, PDCD4, HNRNPDL, JAK1, MSN, SNRPA1, LCP1, IL12RB2, MTAP, CA1, GSTA2, RAP1B, PPIA, BOLA2 |
| interleukin-13 biosynthetic process | biological process | IL18 |
| interleukin-13 production | biological process | IL25 |
| interleukin-13 secretion | biological process | SPHK2 |
| interleukin-13-mediated signaling pathway | biological process | CD300LF |
| interleukin-15 production | biological process | TUSC2 |
| interleukin-15-mediated signaling pathway | biological process | IL15, SHC1, STAT5B, IL15RA, JAK1, GRB2, CD4, IL2RB, IL2RG, JAK3, STAT5A |
| interleukin-17 production | biological process | RFTN1, MR1 |
| interleukin-17 secretion | biological process | NR1H4, ZBTB7B |
| interleukin-17-mediated signaling pathway | biological process | IL17C, IL25, IL17F, IL17RA |
| interleukin-18 production | biological process | NLRP3 |
| interleukin-18 secretion | biological process | GBP5 |
| interleukin-18-mediated signaling pathway | biological process | PDGFB, IL18RAP, ALOX5, IL18BP |
| interleukin-2 biosynthetic process | biological process | IL18, PAWR, IL1RAP |
| interleukin-2 production | biological process | STOML2, CD247, SLC11A1, FCER1G |
| interleukin-2 secretion | biological process | PNP, GPAM, CARD11 |
| interleukin-2-mediated signaling pathway | biological process | IL2RA, SHC1, STAT5B, SYK, JAK1, IL2RB, IL2RG, JAK3, STAT5A, PTK2B |
| interleukin-21 secretion | biological process | FOXP1 |
| interleukin-21-mediated signaling pathway | biological process | JAK1, IL21R, IL2RG, JAK3 |
| interleukin-23-mediated signaling pathway | biological process | JAK2, P4HB, IL12RB1, IL23R |
| interleukin-27-mediated signaling pathway | biological process | IL6ST, JAK2, CANX, IL27, JAK1, CRLF1, EBI3, IL27RA |
| interleukin-3 production | biological process | SLC11A1 |
| interleukin-3-mediated signaling pathway | biological process | CSF2RB, SYK, FCER1G |
| interleukin-33-mediated signaling pathway | biological process | IL1RAP, IL1RL1 |
| interleukin-34-mediated signaling pathway | biological process | IL34 |
| interleukin-35-mediated signaling pathway | biological process | JAK2, CANX, JAK1, IL12RB2, EBI3, IL27RA |
| interleukin-4 production | biological process | ITK |
| interleukin-4 secretion | biological process | NOTCH1, IL1RAP, GATA3, RBPJ, VTCN1 |
| interleukin-4-mediated signaling pathway | biological process | IL2RG, JAK3, STAT6, IL4R |
| interleukin-5 production | biological process | IL25 |
| interleukin-5-mediated signaling pathway | biological process | CSF2RB, IL5RA |
| interleukin-6 biosynthetic process | biological process | BCL10 |
| interleukin-6 production | biological process | IL18RAP, LILRA2, ASH1L, WDR83 |
| interleukin-6 secretion | biological process | LEP, NOS2, SPHK2, TMEM106A |
| interleukin-6-mediated signaling pathway | biological process | IL6, IL6R, IL6ST, STAT3, JAK2, SPI1, SMAD4, CTR9, JAK1, FER, CBL, YAP1, ST18, SOCS3 |
| interleukin-7-mediated signaling pathway | biological process | CISH, SOCS2, IL7, SMARCA4, STAT5B, TSLP, SOCS1, IRS2, IRS1, CRLF2, JAK1, IL7R, IL2RG, H3C1, JAK3, STAT5A, H3C13 |
| interleukin-8 biosynthetic process | biological process | NOD1 |
| interleukin-8 production | biological process | LRRC19, PLA2G1B, LILRA2 |
| interleukin-8 secretion | biological process | LEP, NOS2, RAB1A, CHI3L1 |
| interleukin-8-mediated signaling pathway | biological process | CXCR2, CXCR1 |
| interleukin-9-mediated signaling pathway | biological process | STAT5B, IL9R, JAK1, IL2RG, JAK3, STAT5A |
| intermediate filament bundle assembly | biological process | NEFH, EPPK1, PKP2, KRT14, NEFL |
| intermediate filament cytoskeleton organization | biological process | RAF1, SYNM, ERBIN, CSNK1A1, NEFH, PLEC, MACF1, KRT18, DST, ATXN3, DSP, PRPH, EPPK1, PPL, KRT6C, FAM83H, EVPL, KRT74, EVPLL, BFSP2, INA |
| intermediate filament organization | biological process | VIM, SHH, AGFG1, DES, MTM1, KRT20, KRT71, KLHL24, DSP, EPPK1, KRT17, KRT9, KRT2, GFAP, BFSP2, NEFL |
| intermediate filament polymerization or depolymerization | biological process | NEFL |
| intermediate filament-based process | biological process | VIM, SYNC |
| intermediate mesodermal cell differentiation | biological process | BMP4 |
| intermediate-density lipoprotein particle remodeling | biological process | LIPC |
| intermembrane lipid transfer | biological process | PITPNB, GRAMD1C, SCP2, PRELID1, STAR, PITPNA, PRELID2, PLEKHA3, OSBPL5, ABCG1, OSBPL8, OSBPL2, PRELID3A, PITPNC1, TRIAP1, APOA1, TTPA, CERT1, CPTP, GLTP, PITPNM1, GRAMD1A, OSBP, PLEKHA8, STARD3, PITPNM2, C2CD2L, STARD4, STARD5, PRELID3B, CETP, GRAMD1B, TNFAIP8L3, MTTP |
| intermembrane sphingolipid transfer | biological process | CERT1 |
| intermicrovillar adhesion | biological process | CDHR5, CDHR2 |
| internal peptidyl-lysine acetylation | biological process | BAG6, POR, EP300, KAT2A, KAT2B |
| internal protein amino acid acetylation | biological process | EP300, HAT1, NAA10 |
| interneuron axon guidance | biological process | DLX5 |
| interneuron migration from the subpallium to the cortex | biological process | ARL13B |
| interstrand cross-link repair | biological process | USP1, ERCC1, ATR, RNF8, FANCA, FAN1, EXO5, RPA2, RNF168, SLX1A, FAAP24, RPS27A, FANCD2, FANCF, RPA1, FAAP20, SLX4, MUS81, DCLRE1C, RFWD3, FANCL, FANCG, MSH6, DCLRE1B, UBE2T, CENPX, UBC, RPA3, WDR48, UBA52, ERCC4, RAD51D, FANCC, DCLRE1A, HROB, RAD51AP1, UBB, CENPS, XRCC3, FAAP100, ATRIP, POLN, FANCE |
| intestinal absorption | biological process | VDR, LEP, IREB2, SCARB1, ADRA2A, F11R, MOGAT2, ACO1, SLC26A6, CD36 |
| intestinal cholesterol absorption | biological process | LDLR, LIMA1, NPC1L1, PNLIP, AKR1C1, CD36 |
| intestinal D-glucose absorption | biological process | EZR, PLS1, VIL1 |
| intestinal epithelial cell development | biological process | YIPF6, NKX3-2, PRDM1, YAP1, KLF5, C1GALT1, TIGAR, SPDEF |
| intestinal epithelial cell differentiation | biological process | GATA4, GATA5, NPY, SAV1, CBFA2T2, CDX2, PTK6, PYY |
| intestinal epithelial cell maturation | biological process | HIF1A, TYMS, HOXA5, CDKN1A |
| intestinal epithelial cell migration | biological process | PTPN11 |
| intestinal epithelial structure maintenance | biological process | SOX9, TLR4, ZNF830, INAVA |
| intestinal hexose absorption | biological process | SLC2A5, SLC5A1 |
| intestinal lipid absorption | biological process | NPC1L1, UGCG |
| intestinal lipid catabolic process | biological process | PNLIPRP2 |
| intestinal stem cell homeostasis | biological process | LGR4 |
| intestine smooth muscle contraction | biological process | PTGER3, TACR2, HTR2B |
| intra-Golgi vesicle-mediated transport | biological process | GOSR1, COPB2, COPB1, COPZ1, RAB6B, NSF, VTI1B, TRAPPC3, COPE, RAB6A, TRAPPC3L, COPG1, TRAPPC10, GOSR2, RAB6D, COG8, COPA, GABARAPL2, NAPA, RAB33B, COG1, VTI1A, COG3, COPG2, COG2, COPZ2, NAPG |
| intra-S DNA damage checkpoint | biological process | XPC, MSH2, TIPIN, FANCD2, NEK11, MUS81, MRE11, RAD9B, RAD9A, HUS1, ATF2, HUS1B, EME2, MDC1 |
| intracellular bile acid receptor signaling pathway | biological process | NR1H4 |
| intracellular cholesterol transport | biological process | NPC2, STAR, ABCG1, SERAC1, OSBPL2, NPC1, OSBP, STARD4 |
| intracellular distribution of mitochondria | biological process | OPA1, BHLHA15, CLUH, KAT2A, SYNJ2BP, LRRK2 |
| intracellular estrogen receptor signaling pathway | biological process | ESR1, ESR2, SRC, RBFOX2, TADA3, CARM1, DEFA3, TAF7, PADI2, TRIP4, ARID1A, DDX17, POU4F2, SAFB, DEFA1, EGLN2, PPARGC1B, DDX54 |
| intracellular lipid transport | biological process | FABP3 |
| intracellular mRNA localization | biological process | ZNF385A, CASC3, BICD1 |
| intracellular pH elevation | biological process | CFTR, SLC26A3, NOX1, SLC26A6 |
| intracellular pH reduction | biological process | TTPA, GPR89A, GPR89B, TCIRG1 |
| intracellular protein transmembrane transport | biological process | C2CD5, BCR, RTN2, AKT2 |
| intracellular protein transport | biological process | MYRIP, USO1, ARF4, EIF2D, ARCN1, VPS41, RAB9A, STX12, TBC1D15, SELENOS, IFT22, RAB18, RAB21, TMED5, EVI5, VPS26A, NPM1, RAB11A, SEC23B, SCFD2, RAB2B, RAB40A, USP6NL, SAR1A, VPS29, RIMS2, AP3M1, RAB29, CD74, AP2S1, RAB38, VPS18, IPO11, SNX6, SNX2, SEC31A, COPB2, RAB27A, COPB1, COPZ1, RAB1A, YWHAH, SNX27, RAB6B, DNAJC27, STX8, AP3B1, XPO1, STX10, SRPRA, NSF, SEC24C, SEC13, RAB2A, STX5, WLS, RIMS1, TBCK, SCFD1, RPGR, IPO9, TOMM22, VTI1B, SYNRG, AP1G1, SNAPIN, SLU7, RAB4A, CHML, AP1S2, AP3S2, STX3, RABL3, TBC1D1, EXPH5, IPO4, RAB3C, STX18, RABGAP1, AP3D1, IPO8, RAB6A, AP3M2, RAB25, AP1S1, VPS26B, AP3S1, SYTL4, VPS33B, HGS, VPS26C, RAMP2, RAB5A, RAB31, RAB32, CTTN, STAM, RAB8B, ARL11, VIPAS39, VPS45, RAB20, SNX8, TOM1, AP2A2, PSAP, ARF1, ARF5, RAB40B, AP3B2, RAB35, GPIHBP1, TMED6, ARL6, RAB22A, TBC1D30, RAB27B, IPO5, SCG5, STX17, SEC61G, TBC1D10C, SNX33, TBC1D22B, SNX5, SAR1B, AP1G2, ADPRH, RAB15, TMED2, RAB30, ARL14, AP2M1, TBC1D13, GGA3, STX7, CTSA, RAB3B, RAB14, ARF3, STX1B, TLK1, RAB23, MYO6, SNX9, TBC1D3D, TB |
| intracellular receptor signaling pathway | biological process | NR5A2, AR, AHR, NR5A1, NR1I2, FLT1, NR0B1, STAT3, NCOA2, THRB, NR2F2, NR1H3, NR1D2, PPARD, DCBLD2, RORA, NR2E3, NR4A2, NR1H4, BRD8, NR1D1, SREBF1, NR4A3, AHRR, NR4A1, PPARA, RORC |
| intracellular sequestering of iron ion | biological process | SRI, FTL, FTH1, FTMT, FTHL17 |
| intracellular signal transduction | biological process | CXCL8, TSSK4, TSSK6, HMOX1, MAPK3, MAPK1, TYK2, AKT1, CASP3, GSK3B, ADCY2, DMRT1, HSPB1, LEP, TGFBR3, KIT, SRC, NRG1, RAF1, PLCZ1, CAMK4, MAST2, ADCY10, RASSF1, SIRPG, MAPK14, PLCH2, RASA1, CCN2, DGKK, WNK3, NRBP1, MOK, CAB39, DDX3X, JAK2, STK3, RALGPS1, GPR155, RAB40A, ARHGEF3, CISH, WSB2, NUDT4, MAP3K4, SOCS2, KALRN, PRKAR2A, CHN1, MARK3, DGKE, MAP4K2, MAPK6, PDZD8, ASB17, RPS6KB2, SH2B3, CIT, SHC1, ANP32A, NRG3, STK4, SMAD4, ARHGEF7, MAPK11, TNS2, MARK2, NLRX1, RASGRP3, MAP4K1, WNK4, PLA2G4C, PIKFYVE, RAPGEF2, SOCS5, TGFA, RPS6KB1, PRKCH, MAPK4, IRAK1, DEPDC1, KCTD9, TLK2, DLG5, DEDD2, SOCS4, PASK, ASB8, MAP3K20, STK17A, VAV3, DVL1, IRAK2, STK17B, PRKD1, STK38, RASA2, PREX2, MASTL, PRKAG2, ARFGEF2, DGKB, TRAF3IP2, ROCK2, NFATC1, TFRC, PLEK, MCF2, BCR, BRAF, SYK, ABR, CSPG4, MAPKAPK5, NEK11, NRG4, ASB16, SRPK1, PPP1R1B, RASGRP1, PTPN6, SRPK2, ARHGEF5, SS18, ARHGAP45, LAT2, ASB7, ARHGEF4, PLEK2, SOCS1, DEPDC5, STMN1, RP1, ITK, RAB40B, PLCL1, MAP4K3, RASGRP4, APBB2, MKNK2, SGK2, NOD2, DGKI, MAP4K4, DGKA, ZAP7 |
| intracellular steroid hormone receptor signaling pathway | biological process | ESR1, ESR2, CARM1, CALCOCO1, PLPP1, GPER1 |
| intracellular sterol transport | biological process | NPC2, ARV1 |
| intracellular transport | biological process | APOE, GNAS, VPS41, RGPD4, BBS5, NUP50, MKKS, BBS4, AFTPH, RAB14, SDCBP2, APPBP2, SPIRE1, RANBP3, RGPD2, TMEM167A, RANBP2, BLOC1S6, STBD1, RANBP3L, CSPG5, SPIRE2, RGPD1, FMN2, RGPD8, RASSF9, CLBA1, RGPD5 |
| intracellular transport of viral protein in host cell | biological process | DYNLT1, IFIT1 |
| intracellular transport of virus | biological process | NUP93, NUP37, NUP88, TSG101, NUP85, NUP107, NUP43, POM121, VPS28, NUP35, NUP58, XPO1, SEC13, RPS27A, NUP205, NUP50, NUP62, NUP155, UBAP1, NUP153, CD209, RAE1, SEH1L, RAN, NUP133, VPS37C, UBC, KPNA1, NUP54, TPR, RANBP2, NUP98, UBA52, VPS37A, VPS37B, MVB12A, AAAS, UBB, NUP210, MVB12B, NMT2, NUP188, NUP42, NUP214, NUP160 |
| intraciliary anterograde transport | biological process | IFT52, TTC26, CILK1, IFT122 |
| intraciliary retrograde transport | biological process | DYNC2H1, DYNLL1, TTC21A, WDR19, DYNC2LI1, WDR35, TTC21B, IFT43, CILK1, IFT122 |
| intraciliary transport | biological process | IFT88, IFT57, IFT74, TTC30A, TRAF3IP1, IFT52, TTC26, RPGR, BBS12, WDR35, ARL3, IFT46, LCA5L, WDR34, CILK1, IFT122, LCA5, TUB, IFT172, SSNA1, IFT81, RABL2B |
| intraciliary transport involved in cilium assembly | biological process | IFT88, PCM1, WDR19, IFT22, DYNLRB1, IFT57, KIF17, IFT74, TRAF3IP1, DYNLRB2, IFT52, TTC26, DYNC2LI1, KIFAP3, WDR35, CEP131, IFT46, TTC21B, TRIP11, TNPO1, IFT43, IFT80, WDR60, SSX2IP, CLUAP1, WDR34, IFT122, KIF3C, DYNLL2, IFT172, IFT81 |
| intrahepatic bile duct development | biological process | SOX9 |
| intralumenal vesicle formation | biological process | SNX3, RILP |
| intramembranous bone growth | biological process | FBLN5 |
| intramembranous ossification | biological process | MMP2, CTSK, FGF18, AXIN2, MN1 |
| intrinsic apoptotic signaling pathway | biological process | TP53, CASP4, BAX, CLU, BAD, CYCS, NBN, DDX3X, LGALS12, COA8, MLLT11, HTRA2, CUL1, IFI6, MSH6, CUL5, BNIP3, HIPK2, CUL2, DIABLO, CDKN1A, SIVA1, HRAS, BBC3, SGPP1 |
| intrinsic apoptotic signaling pathway by p53 class mediator | biological process | TP53, BAX, E2F1, HINT1, ZNF385B, TP53BP2, JMY, FHIT, E2F2, IFI16, PML, BOK, PERP, POU4F1, PPP1R13B, POU4F2, PYCARD, MYBBP1A, EDA2R, SHISA5, PDK2, WWOX |
| intrinsic apoptotic signaling pathway in response to DNA damage | biological process | TNF, BCL2, TNFRSF1A, TNFRSF1B, BRCA1, BRCA2, BAX, BAK1, BCL2L2, HMOX1, XPA, CASP9, E2F1, ATM, BAD, MLH1, MCL1, MAEL, MSH2, PIK3R1, BCL2L11, ERCC6, HTRA2, ATAD5, IKBKE, MSH6, CASP2, CRIP1, PRKDC, FNIP2, ABL1, SFN, PML, BOK, NFATC4, BCL2L1, MOAP1, EPHA2, HIC1, PYCARD, POLB, BCL2L10, CIDEB, BCL2A1, TOPORS |
| intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | TP53, BRCA2, BAG6, TP63, MSH2, RPS27L, BCL3, PPP2R5C, USP28, HIPK1, AEN, NUPR1, ATAD5, DYRK2, EP300, HIPK2, IFI16, PML, SNW1, CDIP1, CDKN1A, PYCARD, SHISA5, TMEM109, TOPORS, PHLDA3 |
| intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | BCL2, CASP4, BAX, BAK1, GSK3B, BAG6, BRSK2, DDIT3, DNAJC10, TRIB3, XBP1, DAB2IP, TMBIM6, TMEM117, TNFRSF10B, ERO1A, AIFM1, ATF4, ERN1, MAP3K5, PML, PPP1R15A, UBE2K, ITPR1, ATP2A3, CHAC1, ERN2, ATP2A1, RNF186, TRAF2, BBC3, TP53 |
| intrinsic apoptotic signaling pathway in response to hydrogen peroxide | biological process | PDCD10, STK25 |
| intrinsic apoptotic signaling pathway in response to hypoxia | biological process | BNIP3, TP53 |
| intrinsic apoptotic signaling pathway in response to nitrosative stress | biological process | DDIT3 |
| intrinsic apoptotic signaling pathway in response to osmotic stress | biological process | SCN2A |
| intrinsic apoptotic signaling pathway in response to oxidative stress | biological process | BCL2, GPX1, CYP1B1, ARL6IP5, JAK2, GSKIP, MELK, ZNF622, PDK1, MAP3K5, PML, PRKCD, DIABLO |
| intussusceptive angiogenesis | biological process | CCN1 |
| invadopodium organization | biological process | PDPN |
| involuntary skeletal muscle contraction | biological process | ATP8A2 |
| iodide transmembrane transport | biological process | SLC5A5 |
| iodide transport | biological process | SLC26A4, ANO1, TG, SLC5A5 |
| ion homeostasis | biological process | WNK3, WNK4, EPB42, CRH, WNK1, UMOD, WNK2, SLC4A11 |
| ion transmembrane transport | biological process | ATP6V0A2, CLCA4, RAF1, GJA1, AQP5, CLCN2, CATSPER3, TSC22D3, AQP7, ANXA6, ATP6V1B1, ATP2A2, GABRB1, KCNAB1, ASIC4, ATP6V1D, ATP6V1G1, ATP6V1B2, CHRNA5, ASIC1, NOX1, ASIC2, SLC17A3, GABRA2, ATP8B2, CHRNE, ATP10D, HTR3B, CYBB, CLCN1, HTR3A, PLP2, CNGA2, SLC24A5, CLCNKA, TRDN, ANO6, TMC5, FXYD1, CASQ2, RYR1, ATP6V1E1, CLCN7, RYR2, TMEM120A, ATP13A2, CLIC4, ATP6V0E1, TMEM63A, ATP6V1G2, S100A6, ATP6V1A, ATP2C1, CHRNA2, SGK2, GABRG2, GABRB3, ATP7B, GLRA3, CHRNB1, GABRA5, SLC26A5, FXYD4, ATP1A4, ANO7, CLIC3, CHRNA7, SCNN1G, CHRND, FXYD3, CHRFAM7A, OSTM1, ATP6V1G3, CHRNA10, TRPM3, ATP1A3, GABRB2, GABRA4, CLCNKB, TMC7, GABRG1, ANO9, CHRNA3, GRIA2, ATP1A2, SLC9B2, GPR89A, GPR89B, ATP6V0E2, NEDD4L, PIEZO2, TMEM63C, ATP11B, SGK1, GRIK3, GRIK5, SGK3, WWP1, ATP6V1C1, FKBP1B, ATP7A, ATP2B3, CLIC5, ATP6V1H, GABRP, SCNN1A, ASPH, ATP13A5, CALHM6, UNC80, ATP8A1, CLIC1, GABRD, ATP6V0D1, TPCN2, ATP2A3, ATP6V0B, ATP6V0A4, HTR3E, ATP10A, ATP1B1, GLRA1, AQP1, CHRNA6, TMC4, CALHM5, GRIN3A, GRID2, SCNN1D, FXYD2, ATP6AP1, TMC6, CLIC6, |
| ion transport | biological process | CATSPER1, CATSPER2, CFTR, ATP6V0A2, TF, VDAC2, HFE, LTF, CACNA2D1, SLC22A18, KCNK9, SLC13A3, KCNK17, KCNK4, SLC22A5, MT-ATP6, MT-ATP8, CLCN2, CATSPER4, CATSPER3, SLC26A8, VDAC1, SLC6A8, CACNA1S, NOX5, SLC26A4, ATP6V1B1, ATP2A2, GABRB1, ATP5F1C, SLC26A3, ATP5PO, KCNJ10, KCNAB1, SLC5A8, ASIC4, ATP6V1D, ATP6V1G1, ATP5F1B, ATP6V1B2, ATP5PB, CHRNA5, ASIC1, MLC1, FXN, SLC30A9, SLC30A5, DMAC2L, KCNH6, CNNM2, KCNN3, SCN11A, NOX1, SLC22A2, ATP5MC3, SLC12A2, ASIC2, KCNMB1, SLC15A4, SARAF, KCNJ16, SLC38A7, SLC17A3, KCNK2, ATP5PF, GABRA2, ATP5F1E, CHRNE, GRIN1, TRPC3, SLC38A6, NIPA2, WNK4, KCNMB3, SLCO1B3, SLC31A2, ATP5PD, HTR3B, CYBB, CLCN1, HTR3A, CLDN15, PLP2, CACNA1E, CNGA2, LRRC26, SLC24A5, SLC24A4, SLC20A1, PANX3, COMMD3, KCNH3, KCNH4, CACNG2, CTNS, KCNA4, CLCNKA, KCNH2, ANO6, TMC5, SLC36A1, SLC41A1, SLC22A15, AQP11, KCNN1, SLC22A12, SLC25A18, SLC25A22, PKDREJ, SLC39A9, KCND3, SLC4A7, SLC22A23, FXYD1, KCNN4, RYR1, ATP6V1E1, SLC1A2, CLCN7, SLC15A2, MFSD4B, RYR2, CCDC51, SLC30A2, TTYH2, TMEM120A, CACNG6, SLC38A1, SLC |
| ionotropic glutamate receptor signaling pathway | biological process | APP, GRIN1, CPEB4, GRIA2, GRIN2C, CDK5R1, GRIK3, GRIK5, GRIN2B, CLN3, GRIN3A, GRID2, GRIA3, GRIK4, GRIN2A, GRIN3B, GRIA1, GRID1, GRIN2D, GRIK1, GRIK2, PTK2B |
| IRE1-mediated unfolded protein response | biological process | HSPA5, WFS1, FKBP14, DNAJB11, SERP1, CXXC1, SEC31A, SHC1, GFPT1, KDELR3, VAPB, SRPRA, XBP1, TSPYL2, EXTL2, DNAJB9, PDIA6, EXTL1, MYDGF, ARFGAP1, GET3, HDGF, PARP16, ACADVL, CTDSP2, TPP1, ERN1, SRPRB, GOSR2, SSR1, DNAJC3, PTPN1, WIPI1, ATP6V0D1, SYVN1, HYOU1, CUL7, SULT1A3, ADD1, EDEM1, ZBTB17, TATDN2, EXTL3, YIF1A, PDIA5, DDX11, ERN2, PREB, TLN1, KLHDC3 |
| IRES-dependent translational initiation of linear mRNA | biological process | EIF4EBP1, RBM4 |
| IRES-dependent viral translational initiation | biological process | DENR, EIF2D, MCTS1, EIF3D, EIF3F, SSB, EIF3A, EIF3B, PCBP2 |
| iris morphogenesis | biological process | HIF1A, HIPK1, WNT2B, HIPK2, WNT9A, FOXE3, PITX2 |
| iron assimilation by chelation and transport | biological process | LTF |
| iron import into cell | biological process | SLC39A14 |
| iron import into the mitochondrion | biological process | SLC25A37, SLC25A28 |
| iron incorporation into metallo-sulfur cluster | biological process | FXN, NFS1 |
| iron ion export across plasma membrane | biological process | SLC40A1 |
| iron ion homeostasis | biological process | HMOX1, TF, B2M, HFE, LTF, FXN, FTL, FBXL5, EIF2AK1, EPB42, IREB2, PICALM, STEAP4, HJV, SLC25A37, HMOX2, STEAP2, HEPH, BDH2, SLC25A28, EPAS1, SLC11A1, SLC22A17, SLC40A1, TFR2, STEAP3, SCARA5, MELTF, HEPHL1, TMPRSS6, STEAP1 |
| iron ion import across plasma membrane | biological process | SLC39A8 |
| iron ion import into cell | biological process | HFE |
| iron ion transmembrane transport | biological process | MMGT1, SLC11A1, SLC40A1, SCARA5, TTYH1, MCOLN1, SLC39A14 |
| iron ion transport | biological process | TF, FTL, MMGT1, TFRC, FTH1, IREB2, SFXN1, FTMT, HEPH, SLC11A1, SLC40A1, TFR2, NECTIN1, TTYH1, MELTF, HEPHL1, FTHL17, SLC39A14 |
| iron-sulfur cluster assembly | biological process | IBA57, ISCA2, NUBPL, FXN, ISCA1, NFU1, CIAO2A, CIAO1, NUBP1, CIAPIN1, CIAO2B, NUBP2, ISCU, LYRM4, NDOR1, NFS1, MMS19, CIAO3, HSCB |
| ISG15-protein conjugation | biological process | UBA7, ISG15, UBE2E2, UBE2L6, UBE2E1, HERC5 |
| islet amyloid polypeptide processing | biological process | PCSK2 |
| isocitrate metabolic process | biological process | IDH1, ACO2, IDH3B, IDH2, IDH3G, IDH3A |
| isoleucine catabolic process | biological process | BCAT2 |
| isoleucine metabolic process | biological process | BCAT2 |
| isoleucyl-tRNA aminoacylation | biological process | IARS1, IARS2 |
| isopentenyl diphosphate biosynthetic process | biological process | IDI1 |
| isopentenyl diphosphate biosynthetic process, mevalonate pathway | biological process | PMVK, MVD, MVK |
| isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine | biological process | TGM2, IVL |
| isoprenoid biosynthetic process | biological process | IDI1, PMVK, HMGCR, PDSS2, HMGCS2, HMGCS1, MVD, MVK, CRPPA, PDSS1 |
| isoprenoid metabolic process | biological process | PHYH |
| isoquinoline alkaloid metabolic process | biological process | DDC, TH, CYP2D6 |
| isotype switching | biological process | LIG4, ERCC1, MLH1, RNF8, NBN, MSH2, RNF168, BATF, ATAD5, SWAP70, EXO1, MSH6, EXOSC3, EXOSC6, UNG |
| isotype switching to IgA isotypes | biological process | CCR6 |
| isotype switching to IgG isotypes | biological process | HSPD1 |
| ITP catabolic process | biological process | ITPA |
| ITP metabolic process | biological process | AK3 |
| JAK-STAT cascade | biological process | FGFR3, STAT1, STAT4, PRLR, STAT3, IFNAR2, GH1, PKD1, JAK2, PIAS1, SOCS2, SOCS5, STAT5B, SOCS1, PKD2, CTR9, IFNL1, IFNAR1, GHR, STAT2, SOCS6, STAMBP, IFNL3, IL31RA, STAT6, STAT5A, CLCF1, SOCS3, IFNL4, CCL2 |
| JAK-STAT cascade involved in growth hormone signaling pathway | biological process | MAPK3, MAPK1, PRL, PRLR, STAT3, GH1, JAK2, STAT5B, GH2, GHR, LYN, PTPN1, CSH1, JAK3, STAT6, STAT5A |
| JNK cascade | biological process | TNF, MAPK8, FGF12, MAP4K2, CDC42EP5, MAP3K7, IRAK1, UBE2N, RPS27A, IRAK2, ARHGEF6, TAB1, MAP4K3, NOD2, TNFRSF19, TRIB1, MAP2K4, MAP2K7, HACD3, IKBKG, MAP3K13, MAP3K12, GPS2, UBE2V1, TAB2, MAPK9, RIPK2, MAP3K5, TRAF6, UBC, PTGER4, UBA52, TAB3, MAP3K10, GPS1, SH2D3C, UBB, ADORA2B, DUSP9, SH2D3A, NOD1, NPHS1, ROR2, MAPK8IP2, MINK1, MAPK10, FGF14, CRKL, IRAK4 |
| JUN phosphorylation | biological process | MAPK8, MAPK8IP1, MAPK9, MAPK10 |
| keratan sulfate biosynthetic process | biological process | B4GALT2, B4GAT1, B4GALT4, SLC35D2, B4GALT3, OMD, ACAN, PRELP, B4GALT6, B4GALT1, CHST6, B4GALT5, CHST4, ST3GAL4, B3GNT3, B3GNT4, ST3GAL6, CHST5, ST3GAL1, B3GNT7, CHST2, ST3GAL2, KERA, OGN |
| keratan sulfate catabolic process | biological process | HEXA, HEXB, GLB1, OMD, ACAN, PRELP, GNS, GALNS, KERA, OGN |
| keratinization | biological process | CDC42, KRT38, KRT75, LCE3A, KRTAP10-10, KRT24, KRT73, KRT23, ABCA12, KRT84, KRTAP4-5, KRTAP23-1, KRT6B, TGM1, SPRR1A, KRTAP12-1, KRTAP6-2, LCE2C, KRTAP9-2, KRT6A, KRTAP19-7, KRT18, KRT20, KRTAP19-6, KRT71, SPRR3, KRTAP2-3, KRTAP5-9, KRTAP21-1, LCE1F, PKP4, KRTAP3-1, KRTAP2-4, KRTAP5-8, KRT32, DSP, DSG1, KRTAP17-1, SHARPIN, KRT19, SFN, KAZN, KRTAP19-3, PPHLN1, PPL, SPRR1B, SPRR2B, KRT6C, KRT17, CNFN, KRTAP9-4, KRT81, DSC3, PKP2, LCE2B, DSG2, LCE1C, EVPL, KRT83, DSC2, KRT86, KRT8, IVL, JUP, KRT85, LCE1D, KRT82, SPRR2D, DSG3, KRT9, KRTAP6-1, LCE4A, KRT78, KRT15, CDH3, KRTAP19-2, KRT74, KRTAP13-1, KRTAP4-8, PKP3, KRT14, KRT7, KRT13, KRT2, KRTAP10-1, KRTAP10-3, KRTAP10-6, KRTAP10-9, KRTAP10-11, KRT72, KRT80, KRT77, HRNR, TGM3, KRTAP5-3, KRTAP5-5, DSG4, KRTAP20-1, LCE3D, LCE3E, KRTAP8-1 |
| keratinocyte activation | biological process | KRT2 |
| keratinocyte development | biological process | CDC42, PALLD, IFT74, FLNB, EXPH5, BCL11B, FOSL2, SFN, KDF1, KRT2 |
| keratinocyte differentiation | biological process | CASP3, AKR1C3, KRT10, TP63, TSG101, TXNIP, STK4, ABCA12, INTU, SCEL, ANXA1, BCR, TGM1, SPRR1A, CLIC4, FOXN1, NOTCH1, PIP5K1A, SPRR3, IRF6, FLG, EREG, DSP, SAV1, CSTA, SFN, RBPJ, ADAM9, LATS1, SPRR1B, S100A7, SPRR2B, YAP1, MAP2K1, EVPL, EPHA2, IVL, CERS3, ACER1, JAG1, TGM3, DSG4, ST14, UGCG, WNT16 |
| keratinocyte migration | biological process | PPARD, FERMT1, LTB4R2, KRT2 |
| keratinocyte proliferation | biological process | TP63, PPARD, FERMT1, IRF6, KLK8, EREG, CDH13, KRT2, PTCH1, WNT16 |
| ketone body biosynthetic process | biological process | ACAT1, AACS, ACSS3, SLC27A5, HMGCS2, BDH2, HMGCL, BDH1, HMGCLL1 |
| ketone body catabolic process | biological process | ACAT1, OXCT2, OXCT1, BDH1 |
| ketone catabolic process | biological process | OXCT1 |
| kidney development | biological process | DCN, BCL2, ACE, VEGFA, WT1, BAX, HNF1B, BMP7, CTNNB1, BAG6, ADAMTS1, CAT, BMP4, FGF8, SHH, WFS1, ALDH1A2, PKD1, PYGO2, CA2, GLI3, IFT88, NDUFS6, CYP4A11, RGN, TRAF3IP1, SMAD4, TNS2, BCL2L11, FBN1, CPLANE1, RRM2B, AQP11, DCHS1, ASS1, TSC1, ODC1, ARL3, WNT4, ARID5B, WNT9B, ACVR2B, FSTL3, HPGD, GATA3, PAX8, FADD, PKD2, TIPARP, HAS2, CYP26A1, AGTR1, CENPF, LHX1, OVOL1, TFAP2A, SOX11, RIDA, TGFB2, POU3F3, FOXC2, TGFBR1, TMED10, GREB1L, PYGO1, C1GALT1, BMP6, HYAL2, SIX1, NPHP3, SIX2, WNT11, AMER1, LZTS2, MME, PDGFRB, MPST, PPAT, NLE1, SULF1, SALL1, PKHD1, FOXC1, SERPINF1, GPC3, PROX1, TREX1, LRP4, GLI2, PCSK9, MMP17, SLC34A1, STRA6, GLIS2, UPK3A, AGT, SULF2, RPGRIP1L, ITGA8 |
| kidney epithelium development | biological process | KANK2, PAX8, SALL1 |
| kidney morphogenesis | biological process | HNF1B, ZMPSTE24, PRKX, WNT4, WNT9B, VANGL2, GCNT1, SOX4, NPHP3, WWTR1 |
| kidney rudiment formation | biological process | WNT9B |
| killing by host of symbiont cells | biological process | CAMP, DEFB103A, PF4, DEFA5, DEFA1, MBL2 |
| killing of cells of other organism | biological process | S100A12, CCL20, CCL8, LCE3A, CXCL11, CCL1, RPS19, RPL30, CCL11, DEFB103A, GNLY, CST11, DEFA3, H2BC12, NTS, CCL22, DEFB4A, PF4, DEFA5, PGLYRP4, CXCL2, DEFB132, MUC7, CXCL1, CCL18, CCL19, HAMP, DEFA4, DEFA1, PPBP, CXCL3, CCL28, CXCL14, HMGN2, POMC, CXCL12, CCL17, CCL21, CCL27, CXCL10, HTN3 |
| kinetochore assembly | biological process | CENPE, MIS12, POGZ, CENPN, CENPT, CENPF, CENPX, CENPW, CENPC, CENPA, CENPS, CENPK, CENPH |
| kinetochore organization | biological process | NDC80, SMC4, SMC2, NUF2, CENPH |
| Kit signaling pathway | biological process | KIT, FER |
| Kupffer's vesicle development | biological process | AHI1 |
| kynurenic acid biosynthetic process | biological process | IDO1 |
| kynurenine metabolic process | biological process | KYAT1, AADAT |
| L-alanine catabolic process | biological process | GPT, GPT2, AGXT |
| L-alanine import across plasma membrane | biological process | SLC1A4 |
| L-alanine metabolic process | biological process | GPT2 |
| L-alanine transmembrane transport | biological process | SLC38A5 |
| L-alanine transport | biological process | SLC36A4, SLC38A7, SLC36A1, SLC1A4, SLC36A2, SLC36A3, SLC38A3 |
| L-alpha-amino acid transmembrane transport | biological process | SLC7A5, SLC38A9, SLC38A7, SLC7A6, SLC38A1, SLC7A3, SLC7A8, SLC7A9, SLC7A7, SLC43A1, SLC3A2, SLC7A10, SLC43A2 |
| L-amino acid transport | biological process | SLC7A5, SLC7A8, SLC43A2 |
| L-arginine import across plasma membrane | biological process | SLC7A3, SLC7A1, SLC7A2 |
| L-arginine transmembrane transport | biological process | SLC38A9, SLC25A29 |
| L-arginine transport | biological process | SLC11A1, SLC7A2 |
| L-ascorbic acid biosynthetic process | biological process | RGN, AKR1A1 |
| L-ascorbic acid metabolic process | biological process | CYB5A, SLC2A3, GCLC, GSTO1, GSTO2, CYB5R3, SLC23A1, SLC23A2 |
| L-ascorbic acid transmembrane transport | biological process | SLC23A1, SLC23A2 |
| L-asparagine biosynthetic process | biological process | ASNS |
| L-asparagine metabolic process | biological process | ATF4 |
| L-aspartate import across plasma membrane | biological process | SLC1A5, SLC1A4, SLC1A3 |
| L-aspartate transmembrane transport | biological process | SLC38A7, SLC25A13, SLC25A18, SLC25A22, SLC1A2, SLC1A6, SLC25A12 |
| L-aspartate transmembrane transport | biological process | SLC13A3 |
| L-cysteine catabolic process | biological process | CBS, CDO1, AGXT |
| L-cysteine catabolic process to hypotaurine | biological process | CSAD |
| L-cysteine catabolic process to taurine | biological process | CSAD |
| L-cystine transport | biological process | CTNS, SLC1A4, SLC3A1, SLC7A9 |
| L-fucose catabolic process | biological process | FUT4, FUT6, FUT5, FUT8, FUT9, FUT7, FUT2 |
| L-glutamate import | biological process | SLC1A3, SLC17A7 |
| L-glutamate import across plasma membrane | biological process | SLC1A2, SLC1A3, SLC1A6, NTSR1 |
| L-glutamate transmembrane transport | biological process | ARL6IP5, SLC38A7, SLC25A13, SLC25A18, SLC25A22, SLC1A2, SLC1A3, SLC17A6, SLC1A6, SLC1A7, PRAF2, SLC25A12, SLC17A7 |
| L-glutamine import across plasma membrane | biological process | SLC1A5 |
| L-histidine import across plasma membrane | biological process | SLC7A1 |
| L-histidine transmembrane transport | biological process | SLC15A4, SLC38A7, SLC25A29, SLC38A5, SLC38A3 |
| L-kynurenine catabolic process | biological process | KYNU, KYAT1, ALDH8A1 |
| L-kynurenine metabolic process | biological process | AADAT, GOT2 |
| L-leucine import across plasma membrane | biological process | SLC3A2 |
| L-lysine catabolic process | biological process | AASS |
| L-lysine catabolic process to acetyl-CoA via L-pipecolate | biological process | PIPOX |
| L-lysine catabolic process to acetyl-CoA via saccharopine | biological process | AASS, AADAT, DLST |
| L-lysine import across plasma membrane | biological process | SLC7A3 |
| L-lysine transmembrane transport | biological process | SLC7A3, SLC66A1, SLC7A1, SLC25A29, SLC7A2 |
| L-methionine salvage | biological process | BHMT2 |
| L-methionine salvage from methylthioadenosine | biological process | ENOPH1, APIP, MRI1, ADI1, MTAP |
| L-methionine salvage from S-adenosylmethionine | biological process | ENOPH1, APIP, MRI1 |
| L-methylmalonyl-CoA metabolic process | biological process | MCEE |
| L-ornithine import across plasma membrane | biological process | SLC7A3 |
| L-ornithine transmembrane transport | biological process | SLC7A3, SLC7A1, SLC7A2 |
| L-phenylalanine catabolic process | biological process | ASRGL1, PAH, FAH, HGD, GSTZ1, QDPR, KYAT1, TAT, HPD, PCBD1 |
| L-phenylalanine metabolic process | biological process | PCBD1 |
| L-proline biosynthetic process | biological process | PYCR2, ALDH18A1, OAT, PYCR1, PYCR3 |
| L-proline import across plasma membrane | biological process | SLC36A4 |
| L-serine biosynthetic process | biological process | PSAT1, PSPH, SERINC3, SHMT2, PHGDH, SERINC5, SRR |
| L-serine catabolic process | biological process | CBS, SHMT1, SDSL, SHMT2, SDS |
| L-serine import across plasma membrane | biological process | SLC1A4 |
| L-serine metabolic process | biological process | CBS, SHMT1, PSPH, SHMT2, PHGDH, SRR |
| L-serine transport | biological process | SLC1A5, SLC38A7, SLC1A4, SFXN1, SLC38A2, SLC7A10, SLC38A5 |
| L-threonine catabolic process to glycine | biological process | SDSL, RIDA, GCAT, SDS |
| L-tryptophan transmembrane transport | biological process | SLC36A4 |
| L-xylitol catabolic process | biological process | SORD |
| L-xylitol metabolic process | biological process | SORD |
| labyrinthine layer blood vessel development | biological process | MAPK1, AKT1, ESX1, CCN1, OVOL2, HES1, NSDHL, VASH2, PLCD1, TMED2, RBPJ, JUNB, HEY2, FBXW8, PLG, FZD5, HEY1, VASH1, HS6ST1 |
| labyrinthine layer development | biological process | SENP2, CITED1, VASH2, BIRC6, EGLN1, MAP2K1, CDX2, PCDH12, CDX4 |
| labyrinthine layer morphogenesis | biological process | ESX1, GJB5, NCOA1 |
| lacrimal gland development | biological process | SOX9, SOX10, FGFR2, FOXC1, IGSF3, FGF10 |
| lactate biosynthetic process | biological process | PARK7, PER2 |
| lactate biosynthetic process from pyruvate | biological process | LDHC |
| lactate catabolic process | biological process | LDHD |
| lactate metabolic process | biological process | HIF1A, LDHA, PFKFB2 |
| lactate oxidation | biological process | LDHC, HAO2, HAO1 |
| lactate transmembrane transport | biological process | SLC16A7, SLC5A8, SLC5A12, SLC16A8, SLC16A1 |
| lactate transport | biological process | SLC16A8 |
| lactation | biological process | VDR, VEGFA, HIF1A, PRL, PRLR, XDH, OXTR, DDR1, GC, PAM, SOCS2, KALRN, STAT5B, NEURL1, CCND1, ATP7B, GHRHR, APRT, UPRT, CDO1, NCOA1, NCOR2, MT-CO2, ATP7A, MTX1, HK2, DHODH, FOXB1, PPAT, UMPS, NME1, GOT2, SLC29A1, CAD, STAT5A, SLC6A3, USF2, ZBTB7B, CAV1 |
| lactose biosynthetic process | biological process | B4GALT1, LALBA |
| lactosylceramide biosynthetic process | biological process | B4GALT6 |
| lagging strand elongation | biological process | LIG4, PARP1, PARP2, LIG1, LIG3, POLA1 |
| lambdoid suture morphogenesis | biological process | GLI3 |
| lamellipodium assembly | biological process | KIT, NUP85, WASF3, ARHGEF7, NCK1, VAV3, ARHGEF6, CCDC88A, AJUBA, ARHGEF4, RHOD, ABLIM1, NCK2, S1PR1, P2RY12, RAC1, SPATA13, GOLPH3, WASF2, VAV2, CYFIP1, VCL, CARMIL1, PARVB, PTPRO, CDH13, DMTN, ABLIM2, ABLIM3 |
| lamellipodium assembly involved in ameboidal cell migration | biological process | SRGAP2 |
| lamellipodium morphogenesis | biological process | SNX2, WASF2, PLEKHO1, ABI1, WASF1 |
| lamellipodium organization | biological process | MTSS2, ARPC5, CTTN |
| late endosomal microautophagy | biological process | HSPA8, VPS4B |
| late endosome to Golgi transport | biological process | SNX3, SNX12, SGSM2, GCC2 |
| late endosome to lysosome transport | biological process | VPS41, C9orf72, SNAPIN, VPS39 |
| late endosome to vacuole transport | biological process | CHMP2A, CHMP1A, BECN1, PIK3R4, CHMP7, CHMP3, CHMP1B |
| late endosome to vacuole transport via multivesicular body sorting pathway | biological process | TMEM50B, CHMP5, VTA1, CHMP4A, LEPROTL1, CHMP4B, CHMP6, LEPROT, TMEM50A, CHMP4C, CHMP7 |
| late meiotic recombination nodule assembly | biological process | MCMDC2 |
| late nucleophagy | biological process | ATG9A, ATG9B |
| late viral transcription | biological process | USF1, MON1B, USF2 |
| lateral attachment of mitotic spindle microtubules to kinetochore | biological process | CENPE |
| lateral element assembly | biological process | SYCP1 |
| lateral ganglionic eminence cell proliferation | biological process | GLI3 |
| lateral geniculate nucleus development | biological process | CHRNB2 |
| lateral inhibition | biological process | HES1, DLL1 |
| lateral mesoderm development | biological process | BMPR1A, TEAD2, YAP1, MESP1 |
| lateral mesoderm formation | biological process | TBX20 |
| lateral mesodermal cell differentiation | biological process | FOXF1 |
| lateral motor column neuron migration | biological process | LHX1, RELN |
| lateral semicircular canal development | biological process | GLI3 |
| lateral sprouting from an epithelium | biological process | FGFR2 |
| lateral sprouting involved in lung morphogenesis | biological process | CELSR1, VANGL2 |
| lateral ventricle development | biological process | DNAH5, NUMBL, MYH10, DPCD, NUMB, CDK6, PAX5, AQP1, TSKU, ATP1B2, RPGRIP1L |
| lauric acid metabolic process | biological process | CYP4A11 |
| layer formation in cerebral cortex | biological process | CTNNB1, GLI3, DAB2IP, CDK5R1, CDK5R2, CDK5, MBOAT7, RELN |
| leading edge cell differentiation | biological process | DAB2 |
| leading strand elongation | biological process | PCNA, POLE3, POLE, POLA1 |
| learned vocalization behavior | biological process | NEUROG1, TIFAB |
| learning | biological process | PTGS1, PTGS2, COMT, VDAC1, SYNJ1, ARF4, YTHDF1, GRIN1, NLGN4X, PPP1R9B, PTN, CLDN5, EPHB2, JPH4, PRKN, PPP3CB, NRXN1, JPH3, CNTN2, NTRK2, SHANK2, NRXN3, SLC8A3, PAK6, CNTNAP2, SORCS3, BCHE, ATXN1, NLGN4Y, ATXN1L, MECP2, ATP8A1, UBA6, DLG4, DRD3, GMFB, TH, DRD1, PRKAR2B, SLC12A5, GRIN2A, AAAS, RGS14, CHRNB2, PAK5, NTSR1, NPAS4, CIC, STRA6, SLC8A2, GRM5, RELN, ATAD1 |
| learning or memory | biological process | EGFR, IL1B, ESR2, CASP3, PTEN, NTRK1, PRNP, KCNAB1, FZD9, ZNF385A, GRIN1, EPHB2, CCL11, GHSR, PICALM, CALB1, CRH, GATM, MEF2C, DKK1, CRHBP, CHRNA7, PSEN1, AFF2, UCN, SLC8A3, CNR1, GLP1R, EP300, ADCY8, EGR2, GRIN2B, S100B, SLC2A4, CLN3, BHLHB9, DRD3, POMK, MME, PTPRZ1, PRKAR1B, GRIN2A, PRKCG, GALR3, THRA, SLC8A2, GRM5, SHC3, AMFR, TTBK1, GM2A, AGER |
| left lung development | biological process | SHH |
| left lung morphogenesis | biological process | NODAL |
| left ventricular cardiac muscle tissue morphogenesis | biological process | SMAD4, RYR2 |
| left/right axis specification | biological process | MNS1, SETDB2, AHI1, NOTCH1, ARL13B, SMO, EPB41L5, CITED2, DLL1, IFT172, PITX2 |
| left/right pattern formation | biological process | DNAAF1, IFT57, FOXJ1, DPCD, MEGF8, CITED2 |
| lens development in camera-type eye | biological process | GJA1, PYGO2, CRYBA4, CRYGA, CRYAB, CTNS, CRYGS, TBC1D20, GATA3, MAF, WNT2B, CDON, CRYBA1, DLG1, SLITRK6, SIX3, TBC1D32, PDS5B, TGFBR1, FRS2, NHS, CRYGD, PITX3, CRYGN, TGFBR2, CRYBA2, CRYBB1, LIM2, PROX1, UNC45B, SIX5, CRYBB2, FOXE3, CRYBG3 |
| lens fiber cell apoptotic process | biological process | E2F1, E2F2, SIX3, TGFBR2 |
| lens fiber cell development | biological process | VIM, WNT7B, FRS2, TMOD1, WNT7A, BFSP2, WNT5B |
| lens fiber cell differentiation | biological process | TGFB1, NF2, SKIL, TDRD7, KDM5B, FZR1, MAF, SIX3, CRYGD, PITX3, SMAD3 |
| lens fiber cell morphogenesis | biological process | ABI2, TBC1D20, ATF4, EPHA2, PROX1 |
| lens induction in camera-type eye | biological process | BMP4, HIPK1, HIPK2, SIX3 |
| lens morphogenesis in camera-type eye | biological process | CTNNB1, TDRD7, SKI, SOX11, MEIS1, PITX3, NECTIN1, BCAR3, LCTL, PROX1, SHROOM2 |
| leptin-mediated signaling pathway | biological process | STAT3, LEP, LEPR, BBS2, ADIPOR1, MKKS, BBS4, MT3, UGCG |
| leucine biosynthetic process | biological process | BCAT1, BCAT2 |
| leucine catabolic process | biological process | IVD, AUH, MCCC1, MCCC2, HMGCL, HMGCLL1 |
| leucine import across plasma membrane | biological process | SLC3A2 |
| leucine metabolic process | biological process | BCAT2 |
| leucine transport | biological process | SLC6A15, LLGL2, SLC6A17 |
| leucyl-tRNA aminoacylation | biological process | LARS1, LARS2 |
| leukemia inhibitory factor signaling pathway | biological process | LIF, IL6ST, CTF1, LIFR |
| leukocyte activation | biological process | TOLLIP, EDN1, ZNF3 |
| leukocyte activation involved in immune response | biological process | CLEC7A, SYK, SH2D1B |
| leukocyte adhesion to arterial endothelial cell | biological process | SLC39A8 |
| leukocyte adhesive activation | biological process | CX3CL1, SELPLG |
| leukocyte aggregation | biological process | SEMA4D |
| leukocyte cell-cell adhesion | biological process | ICAM1, ITGB1, ITGA5, CCL5, ITGA4, EZR, OLR1, VCAM1, SYK, NT5E, CD209, UMOD, ROCK1, PTPRC, SELP, MSN, F11R, TSTA3, TNIP1, ITGB2, CALCA, CERCAM, PECAM1, FERMT3, ITGAL |
| leukocyte chemotaxis | biological process | IL10, S100A9, CX3CL1, GPR183, LYST, SBDS, CXCL11, CXCL6, S1PR1, CXCR5, CKLF, PF4, CXCL2, CXCL1, IL16, PPBP, CXCL3, CORO1A, PF4V1, CXCL10, CXCL5 |
| leukocyte chemotaxis involved in inflammatory response | biological process | PTN, SLAMF8, MDK, ALOX5, LBP |
| leukocyte degranulation | biological process | HCK |
| leukocyte differentiation | biological process | RRAS, ID2, SRF |
| leukocyte homeostasis | biological process | BCL2, BAX, BAK1, BCL2L11, CXCL6, NKX2-3 |
| leukocyte mediated cytotoxicity | biological process | STXBP2 |
| leukocyte mediated immunity | biological process | DBH |
| leukocyte migration | biological process | TNF, IL1B, ICAM1, MMP9, CD44, APOB, GAS6, ITGB1, ITGA5, ITGAV, YES1, SRC, ITGA4, MIF, ITGA6, PIK3CA, SLC7A5, FN1, PTPN11, SOS1, ELANE, SIRPA, SIRPG, VPREB1, FOXJ1, CD74, OLR1, EPCAM, PIK3R1, SHC1, CD47, CD58, JAM3, GP6, THBD, CD34, SDC2, FCAMR, SLC7A6, PTPN6, TNFRSF10D, TNFRSF10B, PROS1, SDC4, NKX2-3, ITGAM, CEACAM8, TEK, SLC7A8, ROCK1, SELP, CEACAM6, SLC7A9, GRB7, TREM1, ANGPT4, CD48, ANGPT1, ITGB3, COL1A2, PDE4B, MSN, GRB2, GLG1, GYPA, ADD2, CXADR, F11R, ANGPT2, LYN, B4GALT1, PDE4D, AIMP1, CD2, ITGAX, ITGB7, SELPLG, ESAM, CD244, ATP1B1, ITGB2, CEACAM3, SLC7A7, SLC16A8, CEACAM1, IGLL1, FCER1G, TNFRSF10A, DOK2, ATP1B2, SPN, SLC16A1, JAML, LCK, SLC3A2, SELL, PECAM1, GPC1, MYH9, JAM2, CD84, PIK3R2, GYPC, MAG, ATP1B3, F2, DBH, ITGAL, ITGA3, L1CAM, PPIL2, SLC7A10, MERTK, SDC3, SDC1, INPP5D, PPIA, VPREB3, CAV1 |
| leukocyte migration involved in immune response | biological process | FUT7, HCK |
| leukocyte migration involved in inflammatory response | biological process | S100A9, CX3CL1, RTN4, JAM3, CCR6, ALOX5, S100A8, ITGB2, FUT7, ADAM8 |
| leukocyte tethering or rolling | biological process | TNF, ITGB1, LEP, ITGA4, VCAM1, MADCAM1, ROCK1, SELP, GOLPH3, ADD2, GCNT1, CX3CR1, ITGB7, SELPLG, SPN, SELL, JAM2, PODXL2 |
| leukotriene A4 biosynthetic process | biological process | ALOX5 |
| leukotriene B4 catabolic process | biological process | CYP4A11, CYP4F3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| leukotriene biosynthetic process | biological process | LTA4H, ALOX5AP, MGST3, MGST2, SYK, ALOX5, PLA2G4A, PLA2G1B, LTC4S, PLA2G5 |
| leukotriene D4 biosynthetic process | biological process | GGTLC1, GGTLC2, GGT7, GGT1 |
| leukotriene metabolic process | biological process | ABCC1, LTA4H, ALOX5AP, PTGR1, CYP4A11, CYP4F3, MGST2, ALOX5, LTC4S, DPEP2, CYP4F2, CPA1, GGT1, DPEP1 |
| leukotriene production involved in inflammatory response | biological process | ALOX5 |
| leukotriene signaling pathway | biological process | CYSLTR1, LTB4R, RGS1, LTB4R2 |
| Leydig cell differentiation | biological process | CYP17A1, NR0B1, MGST1, PLEKHA1, CCND1, DHH, SF1, PDGFRA, NKX2-1 |
| limb bud formation | biological process | SOX9, FGFR2, SHH, ZNF219, COL2A1, SOX11, SOX4, SEMA3C, PLXNA2, WNT3, FGF10 |
| limb development | biological process | CTNNB1, BMPR2, NR2F2, SHH, CHD7, GLI3, PAM, TULP3, MAP3K20, INTU, KREMEN1, DKK1, RC3H2, RSPO2, MED31, RNF165, IFT80, EN1, IFT122, SLC39A3, KAT2A, SALL1, RAX, RARG, COMP, MEOX2, KAT2B, SLC39A1, LRP4, WNT3, ZNRF3, WNT7A, FMN1, SMOC1, IFT172, LNPK, FGF10, GREM1, RARA |
| limb epidermis development | biological process | KDF1 |
| limb morphogenesis | biological process | BAX, BAK1, FGF8, GLI3, HOXD13, FBN2, FLVCR1, ZNF141, COL2A1, FAM92A, EVX2, MEGF8, ASPH, TBX3, ALX4, LRP5, PTCH1, IQCE, PKDCC, RPGRIP1L, FGF10 |
| limbic system development | biological process | CNTNAP2, TBX3 |
| linear vestibuloocular reflex | biological process | SLITRK6 |
| linoleic acid metabolic process | biological process | PNPLA8, CYP2J2, CYP4A11, ACSL1, GSTA1, ELOVL2, ELOVL5, ALOXE3, FADS1, ELOVL1, ALOX15B, ELOVL3, ALOX12B, ABCD1, FADS2 |
| lipid biosynthetic process | biological process | ACLY, PRPF19, FDFT1, OLAH, AGPS, AGMO, SC5D, ACSL1, MSMO1, CLN8, CH25H, ACSL5, FA2H, ACSL4, PRKAA2, SREBF1, FAXDC2, ACSS2 |
| lipid catabolic process | biological process | APOB, LIPE, PLCZ1, PLA2G6, PAFAH1B2, BSCL2, PLA2G2A, SULT2A1, PLCH2, PNPLA8, PCCA, LIPF, PAFAH2, PLA2G10, PPT1, PLAAT1, LPL, PLAAT3, ENPP2, CES4A, PLA2G4C, CES1, PLD1, LIPJ, LIPG, LIPA, PRDX6, FAAH2, PLBD2, PLA2G3, GALC, PLCB2, PLCB3, ABHD2, LIPC, PLCD1, NAPEPLD, DDHD2, CLPS, DDHD1, PLCE1, RAB7A, LIPH, PNPLA3, IAH1, PNPLA4, PLA2G4A, PNPLA6, PLA2G15, PLA2G1B, PLA2G7, HINT2, NAAA, PAFAH1B3, SMPDL3B, NEU1, PLA2G12A, PLD2, PLA2G5, DAGLB, PNLIPRP2, NEU4, PNPLA7, NEU2, APOC3, ENPP6, ASPG, ABHD4, MGLL, PLCD4, PLA2G2D, DAGLA, FAAH, PLCG2, PLCH1, PLA1A, PLB1, NCEH1, PNPLA1, PNLIP, AKR1D1, PNPLA5, PLA2G12B, LDAH, LRCOL1 |
| lipid digestion | biological process | CLPS, ARX, PNLIPRP2, ENPP7, PNLIP, ASAH2 |
| lipid droplet formation | biological process | PLA2G4C, ZFYVE1, SQLE, SMIM22, CDS1, AUP1 |
| lipid glycosylation | biological process | B4GALNT1, GLT6D1, B3GALT1, GBA2, ST3GAL4, SLC35C1, ABO, B4GALNT2, ST3GAL2 |
| lipid homeostasis | biological process | APOE, PPARG, USF1, NR1H3, NR1D2, PNPLA8, DDX3X, ABHD5, FBXW7, ABCA12, THADA, ATP13A2, ASGR2, ZBTB20, RBP1, IRS2, ACOX3, ANGPTL3, NR1H4, PNPLA3, CERT1, PNPLA4, ABCB4, HNF4A, ACACA, NFE2L1, CETP, ABCB11, USF2, ABHD4, ACOX2, ACOX1, PNPLA1, PNPLA5, ACOXL, NR1H2 |
| lipid hydroperoxide transport | biological process | SCP2 |
| lipid hydroxylation | biological process | CYP2C8, CYP3A5, CYP2E1 |
| lipid localization | biological process | STOML2 |
| lipid metabolic process | biological process | APOE, HSD17B1, IL1RN, PTGS1, SRD5A2, PTGS2, BRCA1, HSD17B4, APOB, CYP1A2, PON1, HSD17B3, C3, CYP11A1, GPX1, CLU, CYP11B1, SRD5A1, HSD17B2, LEP, PTEN, DECR1, CHKA, PTGDS, SULT1A1, ASAH1, G6PD, CYP11B2, NR2F2, EPHX2, PPARG, LIPE, PTPN11, PLCZ1, PLA2G6, NPC2, PAFAH1B2, BSCL2, GBA, PLA2G2A, SULT2A1, SCD, CIDEA, PLCH2, MLYCD, ACADM, PITPNB, LACTB, IDI1, LBR, AACS, MOGAT1, ARV1, ACBD3, PNPLA8, CEPT1, ERLIN1, PCCA, ATP5F1B, LIPF, UGT2B7, CYP2J2, SCAP, ECH1, MTM1, PTGES3, LCLAT1, MBOAT2, CNEP1R1, PAFAH2, AGPAT1, HACL1, LIPT1, HACD1, PLA2G10, UGT2B10, ACLY, CYP4A11, CYP4F3, HADH, ANGPTL8, ACAD11, SGMS2, PLAAT1, MTMR6, MGST3, LPL, FDFT1, PLAAT3, B4GALNT1, SREBF2, ENPP2, GDPD4, ABHD5, CHPT1, ADIPOR1, MGST2, SRD5A3, OLAH, PLA2G4C, PRKAB1, AGPS, PLPP2, XBP1, ECHS1, LSS, PITPNA, PPARD, PLD1, GDPD3, ECHDC2, ABHD12, OMA1, SULT4A1, SULT2B1, AGPAT2, LYPLA1, IVD, CPT1A, HSD17B7, HDLBP, FABP5, OCRL, PMVK, NSDHL, LIPJ, JAZF1, DHRS9, ELOVL6, MID1IP1, ACP6, ETNK2, PRKAG2, LIPG, SC5D, ACSL3, ACSL1, ALDH3A2, AKR1C2, UCP3, MBTPS1, DHC |
| lipid modification | biological process | MBOAT2, FA2H, LPCAT3, MBOAT7 |
| lipid oxidation | biological process | ALOX5, PLA2G7, ALOX15B, ALOX12B |
| lipid particle organization | biological process | BSCL2, CIDEA, RAB18, FITM1, FAF2, TBC1D20, PPID, DDHD2, SPART, PNPLA3, HILPDA, AUP1, RAB3GAP1, PTGFRN, PPIA |
| lipid phosphorylation | biological process | DGKK, SPHK2, DGKE, DGKB, DGKI, DGKA, DGKG, DGKZ, CERK, DGKH, DGKQ, DGKD, AGK |
| lipid storage | biological process | NRIP1, HEXB, BSCL2, CIDEA, FITM1, PLIN2, B4GALNT1, STAT5B, DGAT2, ANGPTL3, DGAT1, ACVR1C, APOA1, CRY1, PLIN3, DYSF, LDAH, CD36, GM2A, CAV1 |
| lipid translocation | biological process | ABCG1 |
| lipid transport | biological process | APOE, APOB, SERPINA5, CHKA, GRAMD1C, ARV1, ATP10B, SCP2, OSBPL1A, ATP8B3, TMEM30B, PDZD8, ATP8B4, PRELID1, APOL3, ATP8B2, ATP10D, STAR, TEX2, HDLBP, ANO6, ABCA12, STARD6, ABCA4, LDLR, SCARB1, OSBPL5, PSAP, ABCG1, VLDLR, ABCA13, FABP6, APOF, SLC27A1, APOLD1, APOO, OSBPL11, OSBPL8, OSBPL2, STOML1, CLN8, PCTP, ANO7, ABCA5, APOD, PRELID3A, APOL2, PITPNC1, STARD10, ANO9, TRIAP1, APOA1, OSBP2, OSBPL9, TMEM30A, GULP1, CERT1, OSBPL6, ATP8A2, ATP11B, ESYT2, CPTP, MFSD2A, GLTP, APOC1, ABCB4, NPC1, ATP11A, GRAMD1A, OSBPL10, OSBPL7, VPS51, ATP8A1, APOA5, ATP10A, OSBP, SPNS3, SLCO2A1, PLEKHA8, STARD3, ESYT1, C2CD2L, STARD4, SIGMAR1, APOL6, OSBPL3, STARD5, RFT1, ESYT3, GOT2, CETP, SLC27A4, SPNS2, ABCA7, ABCA10, ABCA3, MFSD2B, NME4, ATP8B1, GRAMD1B, LRP10, ABCA2, APOC3, LBP, ANO4, TNFAIP8L3, SPNS1, APOM, MTTP, ABCA6, APOL5, APOL1, GM2A, APOBR |
| lipid transport across blood-brain barrier | biological process | FABP5, SLC27A1, MFSD2A, SLC27A4, CD36 |
| lipid tube assembly | biological process | SH3GL2, SNX9, BIN1 |
| lipid tube assembly involved in organelle fusion | biological process | PCDHGA3 |
| lipoate biosynthetic process | biological process | LIAS |
| lipophagy | biological process | RAB7A |
| lipopolysaccharide catabolic process | biological process | AOAH |
| lipopolysaccharide transport | biological process | SCARB1, LBP |
| lipopolysaccharide-mediated signaling pathway | biological process | TGFB1, TNF, IL1B, NOS3, IL18, MAPK3, MAPK1, AKT1, TLR4, TLR2, CCL5, MAPK14, BCL10, LY96, IRAK1, IRAK2, CCL3, SCARB1, PTPN22, NFKBIA, RIPK2, LYN, PRKCE, BPI, HCK, PTAFR, CD6, IRF3, LBP, CCL2, TICAM1 |
| lipoprotein biosynthetic process | biological process | APOE, APOB, APOA1, APOBEC1, LCAT |
| lipoprotein catabolic process | biological process | APOE, APOB, ATM, LDLR |
| lipoprotein localization to membrane | biological process | ZDHHC3 |
| lipoprotein metabolic process | biological process | APOE, APOB, ALB, OLR1, APOL3, LDLR, APOLD1, APOL2, APOA1, NPC1L1, APOC1, APOA5, LRP1, APOL6, PPARA, PCSK9, APOC3, APOBEC1, APOM, MTTP, APOL5, APOL1 |
| lipoprotein transport | biological process | APOB, PPARG, ZDHHC17, UNC119, PRKCB, MIA3, LRP1, CUBN, APOBEC1, UNC119B, CD36 |
| lipoxin A4 biosynthetic process | biological process | ALOX15B |
| lipoxin biosynthetic process | biological process | ALOX5AP, HPGD, ALOX5, LTC4S |
| lipoxygenase pathway | biological process | PTGS2, GPX1, GPX4, ALOX5AP, PLA2G3, HPGD, ALOX5, LTC4S, ALOXE3, ALOX15B, ALOX12B |
| liver development | biological process | CYP1A1, HNF1B, NODAL, SRD5A1, ACAT1, CTNNB1, TGFBR3, IGF2R, HGF, PIK3CA, ALDH1A2, PKD1, AACS, UPF2, COBL, CEBPG, RB1CC1, RGN, SEC63, CPS1, DDX39B, HNRNPD, MAN2A1, ZMPSTE24, XBP1, PTN, KRAS, HES1, PHF2, ASS1, ASNS, LSR, PKM, AK4, WNT4, BAAT, ARID5B, ACO2, CCND1, NOTCH1, SP3, RELA, PKD2, JARID2, PDX1, HMGCS1, DBP, ONECUT2, PRKCSH, QDPR, ATP7A, ADA, TAF10, CITED2, NKX2-8, HMGCL, ARF6, MPST, GNPNAT1, HRAS, FPGS, HLX, ONECUT1, PROX1, PCSK9, CAD, NF1, SMAD3, GFER, SRSF5, RPGRIP1L, RARA |
| liver regeneration | biological process | FAS, HFE, RAP1A, GLI3, TYMS, RGN, RPL30, WDR35, CCND1, RPL10, PNPT1, VTN, GLI1, HAMP, CLDN1, PTCH1, IHH, PTPN3, SULF2, SRSF5 |
| lobar bronchus development | biological process | WNT7B |
| lobar bronchus epithelium development | biological process | HOXA5, ADAMTSL2 |
| localization within membrane | biological process | RAC1, CDH13, CNIH2 |
| locomotion | biological process | WDR1, JPH3, SCN1B, PSEN1, ATP1A2, GRIN2A, NEFL |
| locomotion involved in locomotory behavior | biological process | FZD4, PPP3CB, SLC25A46, MYO5A, ADGRL3, CLN6 |
| locomotor rhythm | biological process | PTEN, NCOA2, EGR1, KCND2, USP2, NCOR1, ID2, NAGLU, MC3R |
| locomotory behavior | biological process | SOD1, APP, HEXB, GNAO1, PTEN, NRG1, CHD7, ETV5, MYO15A, GAA, B4GALT2, ZNF385A, ALS2, ZDHHC8, APH1B, RASD2, PRKN, QRFP, PPP1R1B, LRRTM1, NEGR1, PEX13, CALB1, SELENOP, ANKH, ALDH1A3, NAV2, DDHD2, PDE1B, GPR88, PAK6, KLHL1, CELSR1, STRN, SNAP25, ESPN, CHRNA3, ADCY8, HPRT1, ATP7A, APBA2, DSCAM, NPY1R, ABAT, MCOLN3, UBA6, APBA1, MEIS1, PITX3, HTR2C, DRD3, GMFB, ASTN1, GRM6, AVP, TH, DRD1, HPGDS, LMX1A, ADCY5, CHRNB2, CHRNA4, SLC18A2, PAK5, DBH, DRD2, ABCA2, OLFM2, ADORA2A, CACNA1B, SLC6A3, CDH23, SOBP, GRM5, CHRNB4, OPRK1, NOVA1, RELN, PENK, NKX2-1, GRM1 |
| locomotory exploration behavior | biological process | NLGN2, CRH, GAD1, ATP1A2, DPP4, DLG4, PRKCE, LRRK2, SLC4A10, PENK |
| locus ceruleus development | biological process | PHOX2A |
| long term synaptic depression | biological process | PTEN, PICK1, CD38, PLK2, ARF1, SHANK2, SORCS2, SRF, DRD1, ABHD6, GRID2IP, GRIA1, PTK2B, SLC24A1 |
| long-chain fatty acid biosynthetic process | biological process | LTA4H, ELOVL6, ACSBG2, CYP2C8, MYO5A, HPGD, ALOX5, QKI, GSTM4, LTC4S, FADS1, CYP2E1, CYP2D6, ACSBG1, ASAH2, CYP2C9 |
| long-chain fatty acid catabolic process | biological process | LIPE, ADTRP, ACADL, AIG1, ABCD1 |
| long-chain fatty acid import across plasma membrane | biological process | SLC27A5, SLC27A1 |
| long-chain fatty acid import into cell | biological process | RPS6KB1, ACSL3, ACSL1, SLC27A1, SLC27A2, SLC27A4, CD36 |
| long-chain fatty acid import into peroxisome | biological process | ABCD1 |
| long-chain fatty acid metabolic process | biological process | PAM, CYP4A11, ACAD9, CPT1A, ACSL3, ACSL1, SLC27A3, SLC27A5, SLC27A1, PNPLA3, ACSL5, ACSL4, SLC27A2, CYP4F12, ACOT2, CYP4F2, SLC27A4, ACSBG1, ACOT4 |
| long-chain fatty acid transport | biological process | APOE, PPARG, LCN1, PLIN2, FABP5, SLC27A3, FABP3, SLC27A1, MFSD2A, LCN12, SLC27A4, CPT1B, CD36 |
| long-chain fatty-acyl-CoA biosynthetic process | biological process | HACD1, ELOVL6, ACSL3, ACSL1, ACSBG2, ELOVL4, HACD2, ELOVL2, ELOVL5, TECR, ACSL5, ACSL4, HSD17B12, ELOVL1, ELOVL3, ACSF3, ACSBG1 |
| long-chain fatty-acyl-CoA catabolic process | biological process | ACOT7 |
| long-chain fatty-acyl-CoA metabolic process | biological process | ACSL3, DGAT2, THEM5, DGAT1, ACSL4, FAR1, FAR2 |
| long-term memory | biological process | MTOR, CAMK4, TAC1, PJA2, PRNP, GRIN1, CTNS, LDLR, NTF4, CALB1, MECP2, ADCY8, SGK1, PRKCZ, CPEB3, PTCHD1, SLC2A4, NFATC4, SRF, KAT2A, RGS14, DRD2, GRIA1, NPAS4, LRRN4, SHANK1, RASGRF1, BTBD9, RELN, SLC17A7 |
| long-term synaptic potentiation | biological process | MAPK1, PTEN, PLK2, NPTN, PTN, STX3, MPP2, LRRTM1, CRH, NTRK2, ITPR3, SHANK2, SLC8A3, SYT12, SNAP25, MECP2, GRIN2C, SNAP47, PRKCZ, GRIN2B, S100B, CRHR2, NFATC4, TSHZ3, DRD1, STX4, GRIN2A, RGS14, LRRTM2, SHANK1, SLC8A2, GRIN2D, PTK2B, RELN, SLC24A1 |
| loop of Henle development | biological process | DLL1, JAG1 |
| low-density lipoprotein particle clearance | biological process | APOB, HMOX1, AP2S1, DGAT2, LDLR, LIPA, ADIPOQ, SCARB1, AP2A2, AP2M1, SOAT1, CLTA, AP2B1, CLTC, NPC1, AP2A1, PCSK9, NCEH1, CD36 |
| low-density lipoprotein particle mediated signaling | biological process | LPL, CDH13, CD36 |
| low-density lipoprotein particle receptor biosynthetic process | biological process | PPARG |
| low-density lipoprotein particle receptor catabolic process | biological process | AP2S1, AP2A2, VLDLR, AP2M1, MYLIP, CLTA, AP2B1, CLTC, AP2A1, PCSK9 |
| low-density lipoprotein particle remodeling | biological process | APOE, APOB, PLA2G2A, PLA2G10, ABCG1, PLA2G3, LIPC, AGTR1, PLA2G7, MPO, PLA2G5, CETP, AGT |
| low-density lipoprotein receptor particle metabolic process | biological process | PCSK9 |
| lung alveolus development | biological process | TGFB3, LIF, FGFR2, BMP4, BMPR2, TNS3, MAN2A1, ERRFI1, HOXA5, ABCA12, FLT4, TMEM38B, MAN1A2, RC3H2, STK40, SMPD3, PDGFA, ATXN1L, FOXP2, ATP7A, ADA, MYOCD, SFTPD, FOXF1, IGFBP5, CIC, PKDCC, STRA6, HS6ST1, PHF14, FGF10 |
| lung cell differentiation | biological process | CTNNB1 |
| lung ciliated cell differentiation | biological process | NFIB |
| lung development | biological process | LIF, VEGFA, NOS3, CYP1A2, FGFR2, NODAL, FGFR1, CTNNB1, BAG6, BMP4, FGF8, SHH, ALDH1A2, FGF9, MYCN, GLI3, CCN2, DNAAF1, ZFPM2, HIKESHI, CCBE1, FBXW7, LHX3, AP3B1, HOXA5, PTN, HES1, BMPR1A, FOXA1, WNT7B, NFIB, CHI3L1, LIPA, TAB1, NOTCH1, SP3, ACVR2B, FSTL3, CRH, YWHAZ, TIMELESS, HSD11B1, PHEX, EIF4EBP1, STK40, SMPD3, EIF4E, LOX, RIDA, EP300, TBX5, MMP14, FOXP2, ADAMTS2, ADA, SMAD2, EPAS1, NPHP3, NKX2-8, SPRY2, FGF18, GLI1, SREBF1, PDPN, CRISPLD2, SLC23A1, MME, TGFBR2, LOXL3, FOXF1, DHCR7, ZIC3, PDGFRA, LAMA5, RBP4, GPC3, PROX1, GLI2, ITGA3, CCDC40, SIM2, STRA6, FGF1, FGF10, NKX2-1 |
| lung epithelial cell differentiation | biological process | SOX9, FOXA1, TMEM38B, ASCL1, SAV1, YAP1 |
| lung epithelium development | biological process | SHH, PKD1, FOXJ1, ERRFI1, WNT7B, FGF10 |
| lung goblet cell differentiation | biological process | HOXA5, AGR2, SPDEF |
| lung growth | biological process | RSPO2, SPRY2, PDGFRB |
| lung induction | biological process | CTNNB1, WNT2B |
| lung lobe development | biological process | BMP4 |
| lung lobe morphogenesis | biological process | LIF, FGFR2, SHH, SEC24B, TGFBR2, FOXF1 |
| lung morphogenesis | biological process | MAPK3, MAPK1, BMP4, FGF8, SHH, AP3B1, FOXA1, WNT7B, STK40, SOX11, SEC24B, SPRY2, MAP2K1, PLOD3, SRF, TGFBR2, FOXF1, FGF10 |
| lung neuroendocrine cell differentiation | biological process | ASCL1 |
| lung proximal/distal axis specification | biological process | FGF10 |
| lung saccule development | biological process | ASXL1, LTBP3, FGF10, NKX2-1 |
| lung smooth muscle development | biological process | SOX9, SRF |
| lung vasculature development | biological process | LIF, ERRFI1, FOXF1, STRA6 |
| lung-associated mesenchyme development | biological process | FGFR2, FGFR1, CTNNB1, SHH, FGF9, PTK7, HOXA5, DPPA4, WNT11 |
| luteinization | biological process | NR5A1, FZD4, STAT5B, PLEKHA1, PDGFRA |
| luteinizing hormone secretion | biological process | TBX3 |
| luteinizing hormone signaling pathway | biological process | LHCGR, EREG |
| luteolysis | biological process | CASP2, MMP19 |
| lymph node development | biological process | TGFB1, IL15, LTB, NKX2-3, CXCR5, FADD, RC3H2, RC3H1, IL7R, PDPN, RIPK3, TNFRSF11A, POLB, SPNS2, CD248, RORC, LTA |
| lymph vessel development | biological process | NR2F2, CCBE1, SOX18, FLT4, SYK, TMEM204, FOXC2, EFNB2, FOXC1, PROX1 |
| lymph vessel morphogenesis | biological process | VEGFA, PKD1 |
| lymphangiogenesis | biological process | BMPR2, CCBE1, SOX18, PPP3CB, FLT4, ACVR2B, FOXC2, PDPN, PTPN14, ACVRL1, PROX1 |
| lymphatic endothelial cell differentiation | biological process | BMPR2, SOX18, ACVR2B, ACVRL1, PROX1 |
| lymphatic endothelial cell fate commitment | biological process | PDPN |
| lymphatic endothelial cell migration | biological process | LGALS8 |
| lymphocyte activation | biological process | CD3E, SLAMF1, CARD11, LAX1 |
| lymphocyte aggregation | biological process | STK10, RAC2, JAM2 |
| lymphocyte chemotaxis | biological process | CCL5, SAA1, CX3CL1, CCL16, CCL20, CCL8, CCL1, CCL14, CCL3, CXCL16, CCL11, CKLF, CCL22, CCL26, CCL18, CCL23, CCL19, CCL3L1, CCL7, ADAM8, CCL17, CCL21, CCL2, CCL15 |
| lymphocyte differentiation | biological process | IKZF1, SPI1, CBFB, PRKDC, LY6D, RELB, FLT3LG |
| lymphocyte homeostasis | biological process | BCL2, SOS1, SKIL, BCL2L11, FOXN1, TNFRSF17, SLC40A1, LAT, SPNS2 |
| lymphocyte migration | biological process | GATA3, CCR6, TBX21, SPNS2 |
| lymphocyte migration into lymph node | biological process | WNK1, CCR7 |
| lymphocyte migration into lymphoid organs | biological process | CRTAM, RET, FUT7 |
| lymphocyte proliferation | biological process | PURA, HPRT1, IMPDH2, IMPDH1, HELLS |
| lymphoid lineage cell migration into thymus | biological process | FOXN1, BCL11B |
| lymphoid progenitor cell differentiation | biological process | BCL2, KIT, BMP4, SHH, SPI1, BATF, TREX1 |
| lymphotoxin A biosynthetic process | biological process | BCL10, IL17F |
| lysine catabolic process | biological process | OGDH, AASS, GCDH, PHYKPL, HYKK, AADAT, PIPOX, DLST, SLC25A21 |
| lysine transport | biological process | SLC66A1, SLC7A1 |
| lysobisphosphatidic acid metabolic process | biological process | ACP6, ABHD6 |
| lysophospholipid translocation | biological process | MFSD2A |
| lysophospholipid transport | biological process | PLA2G10, MFSD2A |
| lysosomal lumen acidification | biological process | ATP6AP2, PPT1, SNAPIN, TMEM199, CCDC115, CLN3, GRN, CLN6 |
| lysosomal lumen pH elevation | biological process | CLN3 |
| lysosomal membrane organization | biological process | ARF1 |
| lysosomal protein catabolic process | biological process | PSAP, LAMP2, TMEM199, CCDC115, CLN3 |
| lysosomal transport | biological process | VPS52, ALS2, USE1, SPTBN5, M6PR, ATP13A2, PSAP, HGSNAT, NEDD4, ARSB, VPS53, NPC1, TMEM106B, VPS51, GRN, LRP1, PCSK9, HSPA1A |
| lysosome localization | biological process | BLOC1S2, ARL8B, KXD1, SNAPIN, FAM98A, SYTL4, VPS33B, BORCS5, KIF1B, BLOC1S1, MAP6, FLCN, TMEM106B, LAMTOR1, HDAC6, DEF8, MYH9, PIP4P1, RAB34, TFEB, VPS33A, PLEKHM2 |
| lysosome organization | biological process | HEXB, GAA, PPT1, LYST, CHMP5, VPS18, ACP2, WASHC5, AKTIP, AP3B1, SNAPIN, MBTPS1, HOOK3, MFSD8, HOOK2, SPG11, HPS4, ARSB, TPP1, TMEM106B, CLN3, LAMTOR1, TPCN2, GRN, CLVS1, FAM160A2, NAGPA, HPS1, TFEB, NAGLU, MYO7A, LRRK2, VPS35, CLN6, ZKSCAN3 |
| lysyl-tRNA aminoacylation | biological process | KARS1 |
| macroautophagy | biological process | MTOR, VDAC1, DYNLL1, NBR1, FUNDC1, CHMP2A, RB1CC1, TMEM74, TSG101, MAP1LC3A, VPS28, VTA1, PRKAB1, VPS4B, CHMP4A, ATG10, TOMM22, VPS36, PRKAG2, PRKN, HGS, ATG12, STAM, CHMP4B, PIK3C3, ZFYVE1, TOMM70, CHMP6, MTERF3, ATG5, ILRUN, ULK1, SQSTM1, MFN1, PINK1, TOMM5, UBXN6, TOMM7, EI24, STAM2, CSNK2A1, TOMM20, WIPI2, VPS37C, MFN2, BECN1, ATG4B, YOD1, GABARAPL1, ATG3, GABARAP, ACBD5, SNF8, PIK3R4, PRKAA2, GABARAPL2, WIPI1, VPS37A, TOMM6, MAP1LC3B, VPS37B, MTMR3, PIK3C2B, CHMP4C, MVB12A, VPS25, PLAA, TBC1D5, HDAC10, PGAM5, ATG101, TCIRG1, DYNLL2, TOMM40, MTMR14, AMBRA1, CHMP3, ATG13, ATG16L1, MAP1LC3C |
| macromolecule glycosylation | biological process | FUT3 |
| macromolecule localization | biological process | LBP |
| macrophage activation | biological process | TLR4, CD93, CRTC3, IL13, FOXP1, TLR1, TMEM106A, SLC11A1, SLC7A2 |
| macrophage activation involved in immune response | biological process | SYK, HAVCR2, SBNO2, TYROBP, PRKCE, DYSF, TREX1, LBP, SUCNR1, TICAM1 |
| macrophage apoptotic process | biological process | CTSL, IRF3 |
| macrophage chemotaxis | biological process | CCL5, SAA1, CX3CL1, NUP85, CCL3, TAFA4, CKLF, EDNRB, SFTPD, AZU1, CCL2 |
| macrophage colony-stimulating factor signaling pathway | biological process | CSF1, MST1R, DOK1, CSF1R |
| macrophage cytokine production | biological process | GAS6 |
| macrophage derived foam cell differentiation | biological process | TGFB1, SOAT1, EP300 |
| macrophage differentiation | biological process | MMP9, VEGFA, CASP8, PARP1, BMP4, CDC42, CSF1, IL15, SPI1, EIF2AK1, NKX2-3, CEBPE, CD4, GAB3, IL31RA, CSF1R, L3MBTL3 |
| macrophage fusion | biological process | CD81 |
| macrophage homeostasis | biological process | BAP1 |
| macrophage migration | biological process | ROR2, MCOLN2 |
| macrophage migration inhibitory factor signaling pathway | biological process | CD74 |
| macropinocytosis | biological process | SNX33, CARMIL1, MAPKAPK3, PYCARD, RAB34, DOCK2 |
| magnesium ion homeostasis | biological process | CNNM2, ANK3, CNNM4, KCNA1 |
| magnesium ion transmembrane transport | biological process | CNNM2, MMGT1, NIPA2, ZDHHC17, SLC41A1, CLDN16, CNNM4, MAGT1, NIPAL3, ZDHHC13, NIPAL1, NIPAL4, NIPA1, NIPAL2 |
| magnesium ion transport | biological process | CNNM2, MMGT1, NIPA2, SLC41A1, CNNM4, MAGT1, NIPAL3, KCNJ2, NIPAL1, NIPAL4, NIPA1, NIPAL2 |
| maintenance of animal organ identity | biological process | USH2A, ADGRV1, NPHP3, PKP2, IQCB1 |
| maintenance of cell polarity | biological process | DLG5, ARPC5, PDLIM1, SLC9A1, DST, NCKAP1L, CARMIL2 |
| maintenance of centrosome location | biological process | GPSM2, ASPM, AKAP9, TBCCD1, SPOUT1 |
| maintenance of chromatin silencing | biological process | UBE2B |
| maintenance of DNA methylation | biological process | DNMT1, UHRF2, USP7, UHRF1, HELLS, ZNF445 |
| maintenance of DNA repeat elements | biological process | TCF7L2, MSH2, MSH6, AXIN2 |
| maintenance of epithelial cell apical/basal polarity | biological process | ANK1, LIN7C, SLC9A3R1, WDR1, LIN7A, PDCD6IP, WNT11, CRB2, LHX2, LIN7B |
| maintenance of ER location | biological process | POLR2M |
| maintenance of gastrointestinal epithelium | biological process | MUC13, SERPINA3, VSIG1, STRAP, MUC6, NOD2, TFF2, CRACD, MUC4, TLR9, TFF1, RBP4 |
| maintenance of Golgi location | biological process | ARHGAP21, UVRAG, TBCCD1 |
| maintenance of granzyme B location in T cell secretory granule | biological process | SRGN |
| maintenance of imprinting at mating-type locus | biological process | ZNF445 |
| maintenance of lens transparency | biological process | CHMP4B, GCNT2, FOXC1 |
| maintenance of location in cell | biological process | APOE |
| maintenance of mitochondrion location | biological process | ALB, ATP2A1 |
| maintenance of mitotic sister chromatid cohesion | biological process | RB1, DSCC1, MAU2, NIPBL |
| maintenance of permeability of blood-brain barrier | biological process | PTGS1, PTGS2, WNK3, LAMC1, SLC12A2, TJP1, DMD, CLDN12, CLDN5, JAM3, LSR, MBP, ACTG1, MFSD2A, F11R, VCL, ESAM, CDH5, GJB6, CLDN1, PECAM1, JAM2, TJP3 |
| maintenance of postsynaptic density structure | biological process | DLG1, ARF6, DLG3, DLG2 |
| maintenance of postsynaptic specialization structure | biological process | OPHN1 |
| maintenance of presynaptic active zone structure | biological process | CTBP2, BSN, ERC2 |
| maintenance of protease location in mast cell secretory granule | biological process | SRGN |
| maintenance of protein localization in endoplasmic reticulum | biological process | HSPA5, TAPT1 |
| maintenance of protein location | biological process | SP100 |
| maintenance of protein location in cell | biological process | RIT2, CD4, CAV1 |
| maintenance of protein location in mitochondrion | biological process | AKT1, PINK1, HK2 |
| maintenance of protein location in nucleus | biological process | NR5A1, HNRNPU, SKP1, BCL3, ARL2BP, ARL2, MORC3, BBS4, TAF3, SUPT7L, PML, CHCHD10, TOPORS |
| maintenance of protein location in plasma membrane | biological process | ANK3, CCDC88A |
| maintenance of rDNA | biological process | ZMPSTE24 |
| maintenance of symbiont-containing vacuole by host | biological process | AQP1 |
| maintenance of synapse structure | biological process | ADGRB3, CBLN2, CHCHD10 |
| maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter | biological process | POLR2I |
| maintenance of translational fidelity | biological process | RPS23, CDKAL1 |
| maintenance of unfolded protein involved in ERAD pathway | biological process | BAG6, USP13, GET4 |
| malate metabolic process | biological process | LIPF, MDH2, MDH1, ME1, FH, MDH1B, ME2, ME3 |
| malate transmembrane transport | biological process | SLC25A11, SLC25A10 |
| malate-aspartate shuttle | biological process | SLC25A13, SLC25A18, SLC25A22, SLC25A12 |
| male courtship behavior | biological process | HEXB |
| male gamete generation | biological process | MCM8, HROB |
| male genitalia development | biological process | WT1, LHCGR, SRD5A2, HSD17B3, SRD5A1, CTNNB1, TEX15, FGF8, SHH, HOXD13, LGR4, DHCR24, WNT9B, BMP5, GREB1L, TBX3, BMP6, PDGFRA, ROR2, ASB1 |
| male genitalia morphogenesis | biological process | KLHL10, SYCP2, FGF10 |
| male germ cell proliferation | biological process | DMRT1, EIF2S2 |
| male germ-line sex determination | biological process | SOX9, MAP3K4 |
| male germ-line stem cell asymmetric division | biological process | ETV5, ING2, ZBTB16 |
| male gonad development | biological process | LHB, ESR1, INHBA, BCL2, WT1, KITLG, LHCGR, FSHR, SRD5A2, SOX9, INSL3, BAX, NR5A1, AMHR2, RXFP2, ESR2, CYP17A1, ERCC1, NR0B1, SRY, DMRT1, SRD5A1, AKR1C3, PRDX4, INSR, KIT, NCOA2, TEX11, INSL6, GATA4, INHA, FGF9, MAS1, MSH2, KLHL10, PATZ1, FANCA, NASP, LRRC6, YBX3, EIF2S2, NCOA4, AGO4, CSDE1, SMAD4, UTF1, BCL2L11, CTSV, CTNNA1, STAR, COL9A3, NKX3-1, ASPM, NUPR1, WNT4, ARID5B, TBC1D20, FSTL3, GATA3, NUDT1, HMGCS1, WNT2B, TGFB2, LRP2, RHOBTB3, RRM1, MMP14, NCOA1, CBL, RNF38, PRKACG, TGFBR1, WDR48, BOK, SOX15, ACVR2A, BCL2L1, SFRP2, SIX4, PDGFRB, BRIP1, BIK, TLR3, KDM5A, HOXA11, TEX19, UBB, HOXA9, CRKL, H3-3A, RARA, GATA1, HOXA10 |
| male mating behavior | biological process | PTEN, OXT, GRIN1, PPP1R9B, NCOA1, Grn |
| male meiosis | biological process | BRDT, HSPA2, MLH1, TEX11, TEX15, DDX4, MLH3, CYP26B1, TDRD9, MAEL, FANCA, MEIOB, TDRKH, AGO4, TDRD12, SPDYA, KIF18A, SYCP2, TEX19, FIGNL1 |
| male meiosis chromosome segregation | biological process | MLH1, TEX11 |
| male meiosis chromosome separation | biological process | M1AP |
| male meiosis I | biological process | BRCA2, BRDT, UBR2, HSPA2, SPO11, REC8, SYCP3, MEI1, MOV10L1, CCNA1, DMC1, Dmrtc2, MEIOB, RAD51C, TRIP13, ING2, MEIOC, SLC2A8, UBB |
| male sex determination | biological process | SOX9, NR0B1, SRY, DMRT1, GNRH1, INSR, FGF9, PTGDR, DHH, SIX4, SF1, INSRR |
| male sex differentiation | biological process | FKBP4, DMRT1, DMRT3, SIX4 |
| malonate catabolic process | biological process | ACSF3 |
| malonyl-CoA biosynthetic process | biological process | ACACA, ACACB |
| malonyl-CoA catabolic process | biological process | MLYCD |
| maltose metabolic process | biological process | GAA, MGAM, GANC |
| mammary duct terminal end bud growth | biological process | CSF1, KDM5B, CCL11 |
| mammary gland alveolus development | biological process | EGF, ESR1, VEGFA, PRLR, DDR1, AREG, SOCS2, HOXA5, CCND1, PHB2, TPH1, ID2, TNFRSF11A |
| mammary gland branching involved in pregnancy | biological process | ESR1, VDR |
| mammary gland branching involved in thelarche | biological process | TGFB1, AREG, PHB2 |
| mammary gland bud formation | biological process | FGFR2, FGF10 |
| mammary gland bud morphogenesis | biological process | SOSTDC1 |
| mammary gland development | biological process | TGFB1, TGFB3, SOX9, BRCA2, NRG1, PYGO2, GLI3, TDGF1, NRG3, BCL2L11, ARHGAP35, HOXB9, WNT3A, NTN1, IRS2, GHRHR, ITGA2, ARHGAP5, FASN, LBH, LEF1, TBX3, NOTCH4, NME1, HOXA9, GLI2, PTCH1, CAV1 |
| mammary gland duct morphogenesis | biological process | NTN1, SCRIB, LRP5, CSF1R, GLI2, PTCH1 |
| mammary gland epithelial cell differentiation | biological process | MGMT, AKT1, PRLR, HOXA5, IRF6, SMO, LBH, LATS1, ZNF703, AKT2, PTCH1 |
| mammary gland epithelial cell proliferation | biological process | MAPK1, BTRC, CCND1, ID2, EPHA2, STAT6 |
| mammary gland epithelium development | biological process | PRLR, JAK2, WNT7B, WNT4, MSX1, MSX2, ATP2C2, WNT3 |
| mammary gland fat development | biological process | CSF1 |
| mammary gland formation | biological process | BMP4 |
| mammary gland involution | biological process | CAPN1, IGFBP5, CAV1 |
| mammary gland lobule development | biological process | FOXB1 |
| mammary gland morphogenesis | biological process | TGFBR2, STAT6 |
| mammary gland specification | biological process | GLI3, FGF10 |
| mammary placode formation | biological process | NRG3, TBX3, TBX2 |
| mammillary axonal complex development | biological process | ZEB2 |
| mammillary body development | biological process | FOXB1 |
| mammillothalamic axonal tract development | biological process | FOXB1 |
| manchette assembly | biological process | TTC26 |
| manchette disassembly | biological process | RSPH6A |
| manganese ion homeostasis | biological process | SLC39A14 |
| manganese ion transmembrane transport | biological process | TMEM165, ATP2C1, SLC30A10, SLC39A8, SLC11A1, ATP13A1, ATP2C2, SLC39A14 |
| manganese ion transport | biological process | TRPC3, ATP2C1, SLC30A10, TRPC7, TRPC1, SLC11A1, TRPC5, TRPC4, ATP2C2 |
| mannitol transport | biological process | SLC26A6 |
| mannose metabolic process | biological process | MAN2B1, MAN2A1, MAN2A2, PMM1, MAN2C1, MAN2B2 |
| mannose to fructose-6-phosphate metabolic process | biological process | MPI |
| mannose trimming involved in glycoprotein ERAD pathway | biological process | MAN1B1, EDEM2, EDEM3, EDEM1 |
| mannosylation | biological process | ALG2, ALG8, PIGM, PIGV, PIGB, ALG1, ALG3 |
| MAPK cascade | biological process | EGFR, EGF, TGFB1, TNF, IL1B, KITLG, IL18, ERBB2, FGFR2, FGFR3, MAPK3, MAPK1, FGFR1, IL2RA, IL5, KIT, CCL5, GFRA1, IL2, NRG1, FGF17, RAF1, NCAM1, CCR5, FGF8, MEF2A, SOS1, DUSP6, IL17RD, FGF3, PSMA3, FGF9, MYC, GDNF, AREG, PSMB1, RASA1, PSMB5, PSMC2, PSMA8, LAMTOR3, MOK, PSMA7, JAK2, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, MAP3K4, MARK3, CSF2RB, PSMD6, MAPK6, BRAP, PSMD1, PSMD14, SHC1, PSMD7, GRIN1, RASGRP3, SPTBN5, RAPGEF2, PDGFB, TGFA, PSMB6, MAPK4, DAB2IP, PSMD10, KRAS, CCL3, PTPRA, PEBP1, PSMD8, PSMC5, PTK2, RASA2, SETX, BRAF, PSMB4, PSME1, SPRED1, MAPKAPK5, NRG4, SRPK1, RASGRP1, ITPKB, PSMB8, PSMD4, SRPK2, SPTBN1, RASAL2, PSMC3, PSMA6, PPM1L, MAP3K15, RASGRP4, FGF23, TEK, MEF2C, RIT2, IRS2, IL3, IRS1, ACTN2, MAP2K4, MAP2K3, TAOK3, MEN1, FGF5, DUSP5, EREG, SPTBN2, PDGFA, CALM1, ANGPT1, MAP3K3, JAK1, MAP2K2, YWHAE, DLG1, FGF20, PSMD12, NRG2, MBP, PSMB9, PSMC4, ZFP36L2, GRB2, PAQR3, KSR1, NLK, PSMD9, PSMA4, MAPK7, PSMD2, MAP3K5, PEA15, FRS2, ZFP36, YWHAB, ZFP36L1, GRIN2B, PSMD5, PSMF1, HBEGF, SPTB, SCG2, PS |
| MAPK export from nucleus | biological process | DUSP16 |
| MAPK import into nucleus | biological process | MAPK3, MAPK1 |
| MAPK phosphatase export from nucleus, leptomycin B sensitive | biological process | DUSP16 |
| marginal zone B cell differentiation | biological process | BCL3, DOCK11, MFNG, CDH17, DLL1, LFNG, PTK2B, DOCK10 |
| mast cell activation | biological process | S100A12, FCGR2B, MRGPRX2, LCP2, FCER1G, NDRG1, RHOH |
| mast cell chemotaxis | biological process | KIT, CCL11, RAC1, PIK3CD |
| mast cell cytokine production | biological process | KIT |
| mast cell degranulation | biological process | KIT, RASGRP1, LAT2, PLA2G3, MRGPRX2, CBL, PIK3CG, PIK3CD, LAT, NR4A3, CPLX2, S100A13 |
| mast cell differentiation | biological process | KIT, GATA3, PIK3CD |
| mast cell mediated immunity | biological process | SERPINB9, SPON2 |
| mast cell migration | biological process | STAT5B |
| mast cell proliferation | biological process | KIT |
| mast cell secretory granule organization | biological process | LYST, SRGN |
| mastication | biological process | NEUROG1, TIFAB |
| maternal aggressive behavior | biological process | OXT, CRHBP, AVP |
| maternal behavior | biological process | MBD2, PTEN, OXTR, OXT, KALRN, CREBRF, AVP, DRD1, NPAS1, BRINP1, DBH |
| maternal placenta development | biological process | AKT1, NODAL, BMPR2, NR2F2, STOX2, PRDM1, TMED2, PRDX3 |
| maternal process involved in female pregnancy | biological process | LIF, FAS, HIF1A, ITGB1, MTOR, MMP7, PLA2G6, AKR1B1, PAM, LGALS9, KPNA6, HAVCR2, APOL2, DSG1, CNR1, RGS2, ANGPT2, NPFF, DSG2, PPAT, ITGA3, IHH |
| maternal process involved in parturition | biological process | CYP1A1, NODAL, EDNRA, OXTR, KALRN, ARNTL, EDN1 |
| mating behavior | biological process | APP, UBE2Q1, MTNR1A, NHLH2, TH, DRD1, MAPK8IP2 |
| maturation of 5.8S rRNA | biological process | EXOSC10, NSA2, RPF1, MTREX, RRP15, MPHOSPH6, NOL9, PRKDC, C1D, EXOSC4, EIF6 |
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | WDR12, PES1, FTSJ3 |
| maturation of 5S rRNA | biological process | SART1 |
| maturation of LSU-rRNA | biological process | NSA2, RPF1, RPL7A, RRP15, NHP2, RPF2, SNU13, RPL10A, EIF6, NOP2, MRPL1, RSL1D1 |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GTPBP4, RPL7, ZNHIT3, RPL35, WDR12, RPF2, NIFK, DDX18, ZNHIT6, RPL7L1, PES1, FTSJ3 |
| maturation of SSU-rRNA | biological process | UTP14C, RPS14, HELQ, RPS19, NOP14, DDX52, SNU13, RIOK1, UTP4, NOB1, RPS28, RIOK3, NOL11, LSM6, TSR3, RIOK2 |
| maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | RPS14, RPS8, MRPS11, DCAF13, RPS19, NOP14, UTP6, PWP2, UTP4, UTP3, RPS16, HEATR1, TSR1, NGDN, NOL10, TSR2, DHX37, DIEXF, FAM207A, BMS1, GTF2H5 |
| mature B cell differentiation | biological process | POU2F2 |
| mature B cell differentiation involved in immune response | biological process | GPR183, FCGR2B, C17orf99 |
| mature ribosome assembly | biological process | C1QBP, DDX3X, SBDS, EFL1, EIF6 |
| MDA-5 signaling pathway | biological process | IFIH1, IRF7, IRF3 |
| mechanoreceptor differentiation | biological process | NTRK1, NTF4, NTRK2, MYO7A |
| mechanosensory behavior | biological process | ETV1 |
| medial motor column neuron differentiation | biological process | LHX3, LHX4 |
| medium-chain fatty acid biosynthetic process | biological process | OLAH, ACOT7, OXSM |
| medium-chain fatty acid catabolic process | biological process | ACADM |
| medium-chain fatty acid metabolic process | biological process | ACADM, CES1, ACAD9, CRAT |
| medium-chain fatty acid transport | biological process | SLC27A1, SLC27A4 |
| medium-chain fatty-acyl-CoA catabolic process | biological process | ACOT7 |
| medium-chain fatty-acyl-CoA metabolic process | biological process | HSD17B4, ACSM2A |
| medullary reticular formation development | biological process | PHOX2B |
| megakaryocyte development | biological process | KIT, PTPN11, ZNF385A, SH2B3, MPIG6B, PTPN6, PIP4K2A, EP300, WASF2, ABI1, MEIS1, SRF, FLI1, ZFPM1, THPO |
| megakaryocyte differentiation | biological process | IL11, MPIG6B, SP3, CDKN2B, ZFPM1, GATA1 |
| meiosis I | biological process | MEI1, M1AP, ESPL1, BCL2L11, CKS2, PSMD13 |
| meiotic attachment of telomere to nuclear envelope | biological process | TERB2 |
| meiotic cell cycle | biological process | AURKC, BRDT, PIWIL2, PIWIL1, SPO11, MSH4, MSH5, REC8, TEX11, SYCP3, TEX15, DDX4, H2AFX, MEI1, STRA8, SYCE1, SPATA22, MND1, PIWIL4, HORMAD1, HORMAD2, TDRD9, MAEL, SLC26A8, PRDM9, NBN, FKBP6, SYCP1, UTP14C, PIWIL3, STAG3, SYCE1L, XRCC2, DMC1, FBXO43, MEIOB, KASH5, MNS1, PSMA8, RBBP8, TUBGCP4, ACTR3, DUSP13, OSGIN2, ZW10, BUB3, PPP2CA, SMC3, RPA1, TRIP13, PSMC3IP, EXO1, SIRT2, EXD1, CCNB1IP1, MRE11, H1-8, TOP6BL, TUBGCP3, RAD21, TDRD12, MEIOC, STAG2, NUMA1, SHOC1, SYCE3, SMC1A, ACTR2, SGO2, REC114, RAD50, RBM7, SIX6OS1, TUBGCP5, SYCP2, MARF1, TUBGCP2, FAM9A, TEX19, TUBGCP6, FAM9C, FAM9B, SUN2, KLHDC3, ANKRD31, NEK2, CCNB3, RAD54L, MCMDC2, TDRD1 |
| meiotic cell cycle checkpoint | biological process | NSUN2 |
| meiotic chromosome condensation | biological process | STRA8, NCAPD3, NCAPH2, NCAPH, SMC4, NCAPD2, INCENP, SMC2 |
| meiotic chromosome movement towards spindle pole | biological process | ACTR3, ACTR2, FMN2 |
| meiotic chromosome segregation | biological process | MLH1, WAPL, NCAPH, SGO1, SMC4, SMC2, NUF2 |
| meiotic chromosome separation | biological process | ESPL1 |
| meiotic cytokinesis | biological process | ACTR3, ACTR2 |
| meiotic DNA double-strand break formation | biological process | STRA8, HORMAD1, MRE11, TOP6BL |
| meiotic DNA double-strand break formation involved in reciprocal meiotic recombination | biological process | ANKRD31 |
| meiotic DNA double-strand break processing | biological process | SLX4 |
| meiotic DNA double-strand break processing involved in reciprocal meiotic recombination | biological process | SIX6OS1, BRIP1 |
| meiotic DNA integrity checkpoint | biological process | HUS1, HUS1B |
| meiotic DNA repair synthesis | biological process | SPATA22, SYCP1, TEX12 |
| meiotic DNA replication checkpoint | biological process | STRA8 |
| meiotic gene conversion | biological process | TEX11, PRDM9, MSH2 |
| meiotic metaphase I plate congression | biological process | MLH1 |
| meiotic mismatch repair | biological process | MSH4, MSH5, MSH2, MSH6 |
| meiotic nuclear division | biological process | MSH4, REC8, MLH1, MEI1, HORMAD1, HORMAD2, BOLL, FKBP6 |
| meiotic nuclear division | biological process | SYCP2L, SYCP2 |
| meiotic recombination checkpoint | biological process | HORMAD1, TRIP13, RAD1 |
| meiotic recombination nodule assembly | biological process | MCMDC2 |
| meiotic sister chromatid cohesion | biological process | HORMAD1, HORMAD2, SGO1, SGO2 |
| meiotic sister chromatid cohesion, centromeric | biological process | BUB1, BUB1B, SGO2, PPP2R1A |
| meiotic spindle assembly checkpoint | biological process | TTK |
| meiotic spindle elongation | biological process | PPP2R1A |
| meiotic spindle midzone assembly | biological process | MLH1, INCENP |
| meiotic spindle organization | biological process | ESPL1, ATRX, TUBG1, MOS, MYH9, TUBG2 |
| meiotic telomere clustering | biological process | UBE2B, ATM, SPO11, MLH1, MEI1, TERB2 |
| melanin biosynthetic process | biological process | ASIP, CTNS, CITED1, MYO5A, SLC45A2, TYR, TRPC1, OCA2, TYRP1, MC1R, DCT |
| melanin biosynthetic process from tyrosine | biological process | TYR, DCT |
| melanin metabolic process | biological process | BCL2, MYO5A, TYRP1 |
| melanocyte adhesion | biological process | KIT |
| melanocyte differentiation | biological process | BCL2, SOX10, KIT, GLI3, USP13, RAB27A, SLC24A5, CITED1, MYO5A, MITF, MEF2C, HPS4, ENPP1, EDNRB, OCA2, LRMDA, EDN3, TYRP1 |
| melanocyte migration | biological process | ZEB2, KIT |
| melanosome assembly | biological process | RAB38, RAB32, HPS4, HPS1 |
| melanosome localization | biological process | RAB27A, VPS33B, MYO5A, VPS33A, GPR143 |
| melanosome organization | biological process | BLOC1S2, RAB29, RAB38, LYST, AP3B1, ASIP, AP1G1, SNAPIN, AP3D1, RAB32, BLOC1S1, DTNBP1, BLOC1S4, BLOC1S6, SHROOM2, GPR143, AP1M1, TYRP1, KIF13A |
| melanosome transport | biological process | RAB11A, BBS2, RAB27A, RAB1A, BBS5, ASIP, MKKS, ARL6, MYO5A, RAB27B, BBS4, RAB11B, DCTN2, BLOC1S6, RAB17, GPR143 |
| melatonin biosynthetic process | biological process | AANAT |
| membrane assembly | biological process | ANK3, SPTBN1, TLCD1 |
| membrane bending | biological process | SH3GL2, PICALM |
| membrane biogenesis | biological process | SERINC1, CLIP3 |
| membrane budding | biological process | ANXA2, WASL, CHMP5, CHMP4A, FNBP1L, CHMP4B, PICALM, SNAP91, CHMP6, AP2M1, P2RX7, CHMP4C, CHMP7, S100A10 |
| membrane depolarization | biological process | PARK7, CACNA1E, CACNG2, SCN1B, CACNA1A, PRKCZ, P2RX7, CACNG4, CACNB4, CHRNA6, EDN1, P2RX4, CHRNB2, CHRNA4, CACNB3, ADORA2A, CACNA1B, SCN5A, SCN3B, CAV1 |
| membrane depolarization during action potential | biological process | CATSPER1, CATSPER2, CATSPER4, CATSPER3, CACNA1S, SCN11A, YWHAH, KCNH2, SCN2A, CACNA1G, SCN1A, CACNA1I, CACNA1H, SCN4A, SCN5A, SCN10A, SCN3B, SCN8A |
| membrane depolarization during atrial cardiac muscle cell action potential | biological process | CACNA1C, SCN5A, CACNB2 |
| membrane depolarization during AV node cell action potential | biological process | CACNA1C, CACNA1G, TRPM4, SCN5A, CACNB2 |
| membrane depolarization during bundle of His cell action potential | biological process | TRPM4, SCN5A |
| membrane depolarization during cardiac muscle cell action potential | biological process | CACNA2D1, CACNA1C, SCN1B, ATP1A2, SLC8A1, HCN2, KCNJ2, CACNA1D, SCN4B, HCN4, SCN5A, SCN2B, SCN3B |
| membrane depolarization during Purkinje myocyte cell action potential | biological process | SCN1B, TRPM4, SCN5A |
| membrane depolarization during SA node cell action potential | biological process | ANK2, CACNA1G, CACNA1D, HCN4, SCN5A |
| membrane disruption in other organism | biological process | DEFA3, DEFA5, DEFA4, DEFA1, RNASE7 |
| membrane docking | biological process | CHP1 |
| membrane fission | biological process | SH3GLB1, CORO1C, CHMP4B, TMCC1, SPAST |
| membrane fusion | biological process | DNM1L, USO1, RABEP1, ANXA7, SNAP23, RIMS1, VTI1B, STX3, BET1L, STX18, VPS33B, UBXN2A, DNM3, OPA1, SNAP29, MX1, OTOF, FER1L5, VAPA, NSFL1C, VAMP3, UBXN2B, HACE1, CHP1, RABIF, NAPA, MYOF, MX2, STX11, YKT6, DYSF, GCA, DNM1, DCSTAMP, NAPG |
| membrane fusion involved in viral entry into host cell | biological process | env |
| membrane hyperpolarization | biological process | CASP1, CFTR, PARK7, SLC26A3, CACNG2, KCNQ3, KCTD7, PRKCZ, ATP1A1 |
| membrane invagination | biological process | SNX3, CHMP2A, CHMP4A, FNBP1L, HGS, FCHO2 |
| membrane lipid catabolic process | biological process | CYP1B1, MGST2, ZPBP2, SMPDL3B |
| membrane lipid metabolic process | biological process | B4GALT4, AGMO, PSAP |
| membrane organization | biological process | YWHAQ, SYNJ1, HSPA8, AREG, ARPC1A, ACTR3, MTSS2, SAR1A, PIK3C2A, ARPC3, AP2S1, FNBP1, YWHAH, FZD4, AP3B1, TGFA, RALA, RPS27A, REPS1, SH3GL2, FCHO1, ARPC5, OCRL, SCARB2, FNBP1L, TBC1D1, VAMP8, GNPAT, TFRC, DAB2, DHCR24, HGS, SYNJ2, LDLR, RAB5A, M6PR, EPS15, CTTN, CCDC88A, STAM, AP2A2, SYT1, PICALM, SLC18A3, PMP2, ADRB2, YWHAZ, SAR1B, AP2M1, PACSIN2, FAM92A, VAMP4, AMPH, KIAA0319, SNX9, EREG, STAM2, CD3G, YWHAE, LRP2, VAMP3, AAK1, MBP, CLTA, GRB2, AP2B1, DVL2, IL7R, CBL, SFN, VAMP7, ACTG1, FCHO2, TGOLN2, UBC, CLTCL1, CRB1, CLTC, CHP1, SLC2A8, YWHAB, ACTR2, UBA52, GAPVD1, HBEGF, EPN1, GAK, DNAJC6, CLN3, TRIP10, AVPR2, YWHAG, NECAP1, REPS2, AVP, CD4, CLTB, BTC, TMEM33, ARPC4, LPCAT2, SYT9, UBB, PIP5K1C, AP2A1, ARRB2, HIP1R, EPN2, ITSN1, BAIAP2L2, SYT2, EPS15L1, BIN1, CHRM2, STON2, SH3KBP1, SGCZ, SGIP1 |
| membrane protein ectodomain proteolysis | biological process | RBMX, ERAP1, SPPL2A, PSENEN, APH1A, PRKCQ, SPPL2B, HM13, PSEN1, BACE2, ADAM9, P2RX7, SPPL3, PSEN2, DAG1, MYH9, BACE1, ADAM19, PRTN3 |
| membrane protein intracellular domain proteolysis | biological process | SPPL2A, APH1B, PSENEN, APH1A, MBTPS1, RELA, SPPL2B, HM13, PSEN1, RHBDD1, MBTPS2, TRAF6, PSEN2, NGFR |
| membrane protein proteolysis | biological process | PARL, SPPL2A, CLPP, SPPL2B, HM13, AFG3L2, RHBDD1, RET, SPPL3, CTSH, TMPRSS6, NAPSA |
| membrane protein proteolysis involved in retrograde protein transport, ER to cytosol | biological process | HM13, RHBDD1 |
| membrane raft assembly | biological process | ANXA2, EMP2, FLOT1, RFTN1, S100A10 |
| membrane raft distribution | biological process | YJEFN3 |
| membrane raft localization | biological process | RALA |
| membrane raft organization | biological process | PPT1, CAV3, DLG1, MYADM, NPC1 |
| membrane raft polarization | biological process | CD2, MAL, DOCK2 |
| membrane repolarization | biological process | KCNH2, KCND3, ATP1A2, ATP1B1, ATP1A1, ATP1B2, KCNE1, KCNIP2, ATP1B3 |
| membrane repolarization during action potential | biological process | KCNH2, KCNE4, KCNJ2, KCNE1, KCNE3 |
| membrane repolarization during atrial cardiac muscle cell action potential | biological process | KCNN2 |
| membrane repolarization during cardiac muscle cell action potential | biological process | KCNH2, KCND3, YWHAE, ATP1B1, KCNJ2, ATP1A1, KCNE1, KCNIP2 |
| membrane repolarization during ventricular cardiac muscle cell action potential | biological process | KCNH2, KCND3, KCNE4, KCNE1, KCNJ8, KCNE3 |
| membrane to membrane docking | biological process | ICAM1, EZR, VCAM1, ROCK1, MSN |
| membrane tubulation | biological process | SH3GL2, OPA1 |
| membranous septum morphogenesis | biological process | FGFR2, FZD2, NSD2, TGFB2, VANGL2, ID2, TGFBR2, FZD1 |
| memory | biological process | IL1B, PTGS1, PTGS2, IGF2, ITGA5, PTEN, IGF1, OXTR, KCNK4, PLA2G6, OXT, B4GALT2, ASIC1, YTHDF1, PLK2, KALRN, FEN1, NTAN1, KCNK2, GRIN1, PTN, HRH1, EIF4EBP2, PPP3CB, LGMN, PPP1R1B, NTF4, JPH3, VLDLR, RIN1, ITPR3, KLK8, CHRNA7, PSEN1, SLC8A3, KCNK10, ADGRF1, PAK6, SORCS3, ATXN1, ATXN1L, CNR1, MECP2, SCN2A, SLC6A4, ADCY8, CX3CR1, S100B, TAFA2, TH, DRD1, CCK, NTF3, GRIN2A, LMX1A, NQO2, CHRNB2, HRH2, ABCA7, PAK5, DBH, ITGA3, CRTC1, CIC, KMT2B, SLC8A2, SHISA7, ATAD1, NETO1, ITGA8 |
| memory T cell activation | biological process | TNFSF4, TCIRG1 |
| memory T cell differentiation | biological process | TSC1 |
| memory T cell extravasation | biological process | F11R, ITGAL |
| memory T cell proliferation | biological process | DOCK8 |
| menaquinone biosynthetic process | biological process | UBIAD1 |
| menaquinone catabolic process | biological process | CYP4F3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| mesangial cell-matrix adhesion | biological process | CD34, CCL21 |
| mesenchymal cell development | biological process | BCL2, NOTCH1, HEY2, FOXC1, ALX1 |
| mesenchymal cell differentiation | biological process | FGFR2, FGFR1, BMP7, ISL1, HMGA2, TGFBR1, BMP2, WWTR1, FOXC1 |
| mesenchymal cell differentiation involved in bone development | biological process | RANBP3L |
| mesenchymal cell differentiation involved in kidney development | biological process | BMP4, SIX2, AMER1 |
| mesenchymal cell differentiation involved in lung development | biological process | FGFR2, FGF10 |
| mesenchymal cell differentiation involved in renal system development | biological process | BMP4 |
| mesenchymal cell proliferation | biological process | SHH, MSX1, FGF7, HAND2 |
| mesenchymal cell proliferation involved in lung development | biological process | FGFR2, CTNNB1, SHH |
| mesenchymal cell proliferation involved in ureter development | biological process | BMP4 |
| mesenchymal cell proliferation involved in ureteric bud development | biological process | BMP4, BMP2, GPC3 |
| mesenchymal smoothened signaling pathway involved in prostate gland development | biological process | SHH |
| mesenchymal stem cell maintenance involved in nephron morphogenesis | biological process | WNT9B, SIX2 |
| mesenchymal stem cell proliferation | biological process | SIX2 |
| mesenchymal to epithelial transition | biological process | WT1, PELO, WNT4, CITED1, GATA3, FZD7, BASP1, TCF15 |
| mesenchymal to epithelial transition involved in metanephric renal vesicle formation | biological process | SMO |
| mesenchymal to epithelial transition involved in metanephros morphogenesis | biological process | BMP4, GDNF, PAX8, SIX2, SALL1, GREM1 |
| mesenchymal-epithelial cell signaling | biological process | HOXA5, WNT2B |
| mesenchymal-epithelial cell signaling involved in lung development | biological process | FGF10 |
| mesenchymal-epithelial cell signaling involved in prostate gland development | biological process | TNC |
| mesenchyme development | biological process | BMP7, BMP2, HAND2 |
| mesenchyme migration | biological process | ACTC1, FOXF1, ACTA2 |
| mesendoderm development | biological process | NODAL, SMAD4, EOMES, BMPR1A, SSBP3, LHX1, ZFP36L1 |
| mesoderm development | biological process | VEGFA, MEST, IKZF1, JAK2, PPP2CA, EXT1, SMAD4, TIE1, ACVR1, WNT3A, ACVR2B, GDF11, HES7, OVOL1, MESD, EPB41L5, FOXC2, PALB2, ACVR2A, IRX3, POU4F1, BTK, HCK, FOXF1, GDF3, CTDNEP1, TBX6, TCF15, SECTM1, ETS2, LHX2 |
| mesoderm formation | biological process | INHBA, NODAL, BMP7, BMP4, BMPR2, NF2, ETV2, TXNRD1, EOMES, WLS, ACVR1, BMPR1A, MSGN1, DKK1, POFUT2, TWSG1, SMAD2, EXT2, CHRD, SRF, CRB2, NR4A3, MESP1, TBX6, TBX19, WNT3, SMAD3, TLX2 |
| mesoderm migration involved in gastrulation | biological process | EPB41L5 |
| mesoderm morphogenesis | biological process | TBX3 |
| mesodermal cell differentiation | biological process | INHBA, FGFR2, ITGB1, BMP4, KDM6B, HMGA2, ITGA2, ITGB3, ITGB4, ITGA3, ITGA8 |
| mesodermal cell fate determination | biological process | BMP4, KLF4, TRIM15 |
| mesodermal cell fate specification | biological process | SIX2, EYA1, HOXA11, EYA2 |
| mesodermal cell migration | biological process | FGF8, MESP1 |
| mesodermal to mesenchymal transition involved in gastrulation | biological process | EOMES |
| mesodermal-endodermal cell signaling | biological process | HMGA2 |
| mesonephric duct development | biological process | HNF1B, PKD1, PKD2, LHX1, GREB1L, WNT11 |
| mesonephric duct formation | biological process | HNF1B, WNT9B |
| mesonephric duct morphogenesis | biological process | GPC3 |
| mesonephric epithelium development | biological process | FGF1 |
| mesonephric tubule development | biological process | HNF1B, PKD1, WNT4, WNT9B, PAX8, PKD2, LHX1 |
| mesonephric tubule formation | biological process | SIX1 |
| mesonephros development | biological process | BMP7, BMP4, FGF8, WNT4, GATA3, PAX8, LHX1, ZBTB16, OSR2, FGF10 |
| messenger ribonucleoprotein complex assembly | biological process | NUDT21, CPSF7, CPSF6 |
| metabolic process | biological process | RAG1, OGG1, GSTM1, NAT2, MTHFD1, MTHFR, MGEA5, HEXA, HEXB, GSTP1, HSD3B1, ACAT1, HSD3B2, CBS, LYZ, MAN1B1, AMY2A, ARSA, EPHX2, SPAM1, LIPE, UAP1, PLA2G6, ALDH1A2, PGAM1, PGAM4, STARD9, CDY2A, CDY1, MAN2B1, GBA, GAA, GLB1, ENGASE, FUCA1, PAM, RNGTT, PAH, PFKM, MTHFD2, NEIL1, NDST4, GLA, GART, EPRS1, CPS1, ATIC, FDFT1, GYS2, PFKP, MAN2A1, FOLH1B, MGAM, ECE2, EEF1AKMT4-ECE2, SI, PAICS, LARGE2, CEMIP, LYZL6, MOCS3, TKFC, CAMK1D, UGDH, GUSB, BRAF, HEXD, AASS, PKM, IDE, SMPD1, HLTF, LARGE1, FBP1, PC, PRDX6, MAN2A2, GANC, NEIL2, GNE, NAALAD2, DNPH1, MAN1A2, FTCD, LCT, XRCC6, AGL, GALC, PGGHG, MANBA, PFKFB2, ALDH18A1, NTHL1, MUTYH, HADHA, FASN, LYZL1, LYZL2, NDST1, GPHN, TREH, HYAL3, ERN1, NAGA, RRM1, CTBS, ZRANB3, FUCA2, CEMIP2, SAMHD1, PRKG1, GBA2, PDE11A, GSTZ1, H6PD, FOLH1, MTHFD2L, ALG13, PAPSS2, ALAD, GCH1, HK2, NDST3, HYAL2, TSTA3, SMPDL3B, NEU1, PYGL, PYGB, NDST2, ACACA, FBP2, PLOD3, PAK3, PDE5A, IDUA, BDH1, PPAT, GLB1L3, MAN2C1, UMPS, ME2, COASY, PFKFB4, GLB1L, ALKBH8, MAN1C1, PDE10A, GYS1, PFKL, DCTD, MAN1A |
| metabolite repair | biological process | NAXD |
| metal ion homeostasis | biological process | COX11, SLC7A8, CNNM4 |
| metal ion transport | biological process | SLC39A9, SLC39A12, ATP7B, SLC39A10, ATOX1, SLC39A5, SLC39A11, SLC8A3, SLC39A8, LRP2, SLC39A6, SLC39A13, NDFIP1, NDFIP2, ARMC1, ATP7A, SLC11A1, ATP1B1, SLC39A3, ATP1B3, SLC39A4, SLC39A1, SLC39A14, TRPM6, SLC39A7 |
| metanephric ascending thin limb development | biological process | PKD1, PKD2, UMOD, POU3F3 |
| metanephric collecting duct development | biological process | BMP4, PKD1, AKR1B1, AQP2, DLG5, WNT7B, CALB1, PTCH1 |
| metanephric comma-shaped body morphogenesis | biological process | PAX8, LHX1, PDGFRB |
| metanephric connecting tubule development | biological process | CALB1 |
| metanephric cortex development | biological process | PKD2 |
| metanephric cortical collecting duct development | biological process | PKD2 |
| metanephric DCT cell differentiation | biological process | POU3F3 |
| metanephric distal convoluted tubule development | biological process | CALB1, PAX8, UMOD |
| metanephric distal tubule development | biological process | PKD2 |
| metanephric distal tubule morphogenesis | biological process | PKD1 |
| metanephric epithelium development | biological process | WT1, WNT7B, PAX8 |
| metanephric glomerular capillary formation | biological process | PDGFRB, PDGFRA |
| metanephric glomerular mesangial cell development | biological process | PDGFB |
| metanephric glomerular mesangial cell differentiation | biological process | CD34 |
| metanephric glomerular mesangial cell proliferation involved in metanephros development | biological process | PDGFRB |
| metanephric glomerular mesangium development | biological process | PDGFRB |
| metanephric glomerulus development | biological process | LGR4, LHX1 |
| metanephric glomerulus morphogenesis | biological process | PDGFRB |
| metanephric loop of Henle development | biological process | WNT7B, POU3F3 |
| metanephric macula densa development | biological process | POU3F3 |
| metanephric mesenchymal cell differentiation | biological process | STAT1, WNT4 |
| metanephric mesenchymal cell migration | biological process | PDGFRB |
| metanephric mesenchymal cell proliferation involved in metanephros development | biological process | STAT1, BMP7, SHH |
| metanephric mesenchyme development | biological process | WT1, PKD2, BASP1, SIX1, SIX4, PDGFRB |
| metanephric mesenchyme morphogenesis | biological process | BMP7, SMAD4 |
| metanephric nephron development | biological process | WNT4 |
| metanephric nephron morphogenesis | biological process | WNT4 |
| metanephric nephron tubule formation | biological process | SOX9, PAX8 |
| metanephric nephron tubule morphogenesis | biological process | LGR4, HES1 |
| metanephric part of ureteric bud development | biological process | FOXJ1, CALB1, PKD2, LHX1 |
| metanephric proximal convoluted tubule development | biological process | ACAT1 |
| metanephric proximal tubule development | biological process | PKD1 |
| metanephric renal vesicle morphogenesis | biological process | LHX1 |
| metanephric S-shaped body morphogenesis | biological process | WT1, PAX8, PKD2, LHX1, PDGFRB |
| metanephric smooth muscle tissue development | biological process | PKD2 |
| metanephric thick ascending limb development | biological process | UMOD, POU3F3 |
| metanephric tubule development | biological process | SOX9, WNT9B |
| metanephric tubule formation | biological process | WNT4, WNT9B |
| metanephric tubule morphogenesis | biological process | CXCR2 |
| metanephros development | biological process | BCL2, BMP7, BMP4, FGF8, SHH, GDNF, GLI3, IRX1, FBN1, NKX3-1, APH1A, SPRY1, WNT4, CITED1, ROBO2, GDF11, ID3, PAX8, LHX1, NIPBL, FOXC2, GREB1L, IRX3, SIX2, ID2, HOXC11, RDH10, EYA1, HOXA11, CTSH, NF1, OSR2, FGF10, ITGA8 |
| metanephros morphogenesis | biological process | CTNNB1, WNT7B, FRAS1, FGF10 |
| metaphase plate congression | biological process | CENPE, TRAPPC12, NDC80, FAM83D, GEM, CENPF, KIF2B, MEIOC, SPICE1, CENPQ, INCENP, KIF22 |
| metaphase/anaphase transition of mitotic cell cycle | biological process | CDC16, CDC23, ANAPC7, TACC3, CDC27, ANAPC1 |
| metencephalon development | biological process | OTX1, KAT2A |
| methionine biosynthetic process | biological process | MTHFD1, MTR, MTRR, ENOPH1, APIP, BHMT2, MRI1, ADI1, MTHFD2L |
| methionine catabolic process | biological process | MAT1A |
| methionine metabolic process | biological process | MTHFD1, MTHFR, MTRR, MSRA, GNMT, ADI1, SMS |
| methionine transport | biological process | SLC38A7 |
| methionyl-tRNA aminoacylation | biological process | MARS1 |
| methotrexate transport | biological process | SLC19A1 |
| methyl-branched fatty acid metabolic process | biological process | HACL1, PHYH, SLC27A2 |
| methylation | biological process | CYP1A2, MGMT, DNMT1, EZH2, MTR, DNMT3B, MTRR, NSUN7, COMT, PRMT6, PRDM9, PCMT1, GAMT, SETD3, METTL25, TYMS, TRMT2A, METTL2A, PRDM13, METTL7A, NSUN2, METTL2B, CARM1, NSD1, NSD3, TFB2M, SETD4, GNMT, NDUFAF5, METTL21C, EEF1AKMT1, SETDB2, MAT2B, DIMT1, ECE2, EEF1AKMT4-ECE2, NSUN6, COQ3, PRDM2, KMT5B, NDUFAF7, METTL21A, TRMT5, HENMT1, TYW3, SETD9, EHMT2, METTL18, ATPSCKMT, SETD6, TRMT61A, TRMT13, PEMT, NSUN5, PRDM8, KMT2D, RNMT, PRDM1, PRMT2, GSTO1, TRMT10C, METTL5, METTL15, FTSJ1, TRMT44, CMTR2, FAM86B1, METTL6, THUMPD2, BHMT2, NSUN3, EHMT1, PRMT8, TRMT9B, TPMT, COQ5, DOT1L, NSD2, KMT2A, MEPCE, KMT2C, EEF2KMT, ANTKMT, SETD5, LCMT1, SETD1B, FBL, AHCY, EMG1, TGS1, THUMPD3, NTMT1, ARMT1, BUD23, CARNMT1, SETD7, EEF1AKMT3, METTL22, TRMT61B, PRDM6, MAT2A, SETDB1, BMT2, TRMT1L, RAMAC, DPH5, VCPKMT, PRDM4, HNMT, METTL23, TFB1M, LRTOMT, SUV39H2, ASH1L, TRDMT1, ETFBKMT, PRMT1, PRDM12, NOP2, KMT5C, TRMT10A, METTL17, MECOM, SPOUT1, SMYD5, PRDM5, CAMKMT, CMTR1, ALKBH8, MRM3, PRDM10, FAM86C1, LCMT2, MTAP, TRMT1, HEMK1, FTSJ3, |
| methylation-dependent chromatin silencing | biological process | MBD3L1, MBD2, MBD1, MBD3, HELLS |
| methylglyoxal biosynthetic process | biological process | TPI1 |
| methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione | biological process | PARK7, PNKD, HAGH |
| methylglyoxal metabolic process | biological process | GLO1 |
| mevalonate transport | biological process | SLC16A1 |
| MHC class Ib protein complex assembly | biological process | TAPBP |
| MHC class II biosynthetic process | biological process | SLC11A1 |
| MHC class II protein complex assembly | biological process | HLA-DMB |
| microglia development | biological process | TSPAN2, NRROS |
| microglial cell activation | biological process | IL4, CLU, AIF1, CX3CL1, JAK2, IFNGR1, SNCA, IL13, ITGAM, NAMPT, TREM2, ITGB2, FPR2, TLR7, AZU1, TLR3, C1QA, TLR6, TNF, C5AR1, AGER, TRPV1 |
| microglial cell activation involved in immune response | biological process | TYROBP, TREM2, GRN |
| microglial cell migration | biological process | P2RY12, P2RX4 |
| microglial cell proliferation | biological process | CLU, IL34, TREM2, CSF1R |
| microspike assembly | biological process | MTSS1, ACTN2, ABL1, FSCN1 |
| microtubule anchoring | biological process | PCM1, CEP57, CEP20, BCCIP, CEP350, CEP43, SAXO1, CCDC187, PEX14, GCC2, CLASP2, DAG1, CLASP1, CAMSAP3 |
| microtubule anchoring at centrosome | biological process | PCM1, CEP19, NIN, HOOK3, BBS4, CCDC68, NINL |
| microtubule anchoring at microtubule organizing center | biological process | BICD1, BICD2 |
| microtubule bundle formation | biological process | KIF20A, TPPP3, NAV1, TPPP2, CDK5RAP2, ZNF207, CCDC66, PRC1, PLK1, TTLL6, MAP2, GAS2L1, CLIP1, MAP1S, NUMA1, CHP1, MAPRE1, GAS2L2, PSRC1, AAAS, MTCL1, TPPP, FES, CLASP1, MARK4, NCKAP5L, NCKAP5, CCSER2, MAP1B, TRIM46, SPAST |
| microtubule cytoskeleton organization | biological process | CDK1, WEE1, GAPDH, CAMSAP1, BCCIP, TUBGCP4, KIF2A, NUSAP1, MARK3, CAMSAP2, MAP7D1, CUL9, RNF19A, TOGARAM1, MARK2, NEFH, CALML6, TACC1, PTK2, TTLL7, CDK5RAP2, MAP4, TACC2, TTLL1, TUBB2A, SS18, MAP6D1, DISC1, PRC1, CEP120, PARD3B, DYNC1LI2, WDR47, CNTN2, BBS4, TUBE1, DST, CCDC170, VAMP4, ATXN3, TTBK2, PARD3, TACC3, TUBB, CALM1, CALM2, CALM3, TTLL6, TTL, TUBGCP3, TTLL2, CNP, MAP2, SON, TUBB4B, TTLL4, CDK5R1, PHLDB2, DOCK7, GAS2L1, CDC14B, ZPR1, TUBG1, MAP1S, TTLL11, ULK4, EFCAB11, DYNC1LI1, FER, TTLL9, OBSL1, GABARAP, PRKCZ, TAOK1, GAS2L3, MAP6, SIK3, KNSTRN, TUBA1C, EML2, TUBB4A, TUBA3E, CALML4, CUL7, TBCE, TUBGCP5, TBCD, CALML5, EML1, MID1, CLASP2, PCNT, TUBB8, GAS2L2, CDK5, TUBGCP2, TUBB6, TUBAL3, CALML3, TUBGCP6, CCDC8, EML4, GAS2, APC2, EML3, TUBG2, ATXN7, CRMP1, TOGARAM2, CLASP1, MARK4, CAMSAP3, MARK1, MAP1B, TRIM46, MAP7D3, NEFL, SPATA7 |
| microtubule cytoskeleton organization involved in establishment of planar polarity | biological process | BRSK1 |
| microtubule cytoskeleton organization involved in homologous chromosome segregation | biological process | KASH5 |
| microtubule cytoskeleton organization involved in mitosis | biological process | TACC3 |
| microtubule depolymerization | biological process | STMND1, KIF2A, KIF24, KIF14, STMN1, STMN3, KIF2B, KIF18A, CKAP5, KIF18B, NCKAP5L, NCKAP5 |
| microtubule nucleation | biological process | BLOC1S2, TUBGCP4, TPX2, CSNK1D, TUBGCP3, AKAP9, TUBG1, SLAIN2, TUBGCP5, CLASP2, TUBGCP2, TUBGCP6, NDE1, GOLGA2, TUBG2, CLASP1 |
| microtubule nucleation by interphase microtubule organizing center | biological process | TUBGCP4, MZT1, TUBGCP3, TUBGCP5, TUBGCP2, TUBGCP6 |
| microtubule nucleation by microtubule organizing center | biological process | TPPP |
| microtubule organizing center localization | biological process | ARPC5 |
| microtubule organizing center organization | biological process | HAUS2, CDK5RAP2, SDCCAG8, GCC2, BCAS3, CLASP2, NDE1, CLASP1 |
| microtubule plus-end directed mitotic chromosome migration | biological process | CENPE |
| microtubule polymerization | biological process | TPPP3, PIN1, TPPP2, ZNF207, CKAP5, HDGFL3, MAPRE1, TPPP, MAP7D3 |
| microtubule polymerization or depolymerization | biological process | CRYAB |
| microtubule severing | biological process | KATNB1, KATNA1, TTLL6, TTLL11, LZTS2, FIGNL1, KATNAL2, SPAST |
| microtubule sliding | biological process | SPAG16, MAP4 |
| microtubule-based movement | biological process | NGF, DNAH9, KIF3B, NTRK1, KIF26B, KIF6, DNAH12, DYNC2H1, DNAH1, STARD9, KIF3A, DYNC1H1, DNAH5, DNAH11, KIF5B, CENPE, DNAH6, DYNLRB1, ACTR10, DNAH2, KIF17, DNAH17, KIF2A, KIF20A, KIF1C, WDR63, DYNLRB2, KIF19, KIF24, KLC2, KIF15, KTN1, KIFAP3, DYNC1I1, KLC1, DYNC1I2, KIF14, KIF12, KIFC1, DYNC1LI2, KIF1B, KIF16B, DNAH3, KIF5A, KIF2B, DNHD1, DNAI2, WDR78, KIF20B, DNAL4, DYNC1LI1, DNAH10, KIF18A, BICD2, WDR60, DNAH8, KIFC3, WDR34, KIF27, KIF9, KIF4A, KIF3C, KIF1A, KIF23, KIF13B, KIF21B, KIF7, KIF18B, KIF25, KIF26A, KIF4B, DNAH14, KIF11, KIF22, KIF13A |
| microtubule-based peroxisome localization | biological process | PEX13, PEX1 |
| microtubule-based process | biological process | TUBB2B, TUBB3, TUBA4A, TUBA3C, TUBA8, DYNLL1, KIF17, VBP1, KIFAP3, DCTN3, TUBB2A, TUBE1, TUBB, TUBA3D, TUBB4B, DNAL4, TUBG1, KIFC3, DCTN2, TUBA1C, GTSE1, TUBB4A, TUBA3E, TUBB8, TUBB6, TRIM54, TUBAL3, EML4, DYNLL2, TUBG2 |
| microtubule-based transport | biological process | HTT |
| microtubule-dependent intracellular transport of viral material towards nucleus | biological process | DYNLT1 |
| microvillar actin bundle assembly | biological process | ESPN |
| microvillus assembly | biological process | EZR, RAP1A, RAP2B, RAPGEF2, SLC9A3R1, RAPGEF6, MAP4K4, TNIK, STK26, RDX, KLF5, RAP2A, MINK1, RAP1B |
| microvillus organization | biological process | PTPN11, GLDN |
| micturition | biological process | PSAP, ADRA1A, KCNMA1 |
| midbody abscission | biological process | CHMP2A, KIF20A, CEP55, CHMP5, VPS4B, CHMP4A, CHMP4B, CHMP1A, CHMP6, MITD1, PDCD6IP, CHMP4C, CHMP7, CHMP3, CHMP1B |
| midbrain development | biological process | FGFR2, FGFR1, CTNNB1, OTX1, SHH, WLS, DLG5, HES1, WNT3A, FZD3, MSX1, LRP6, CXCR2, TAF1, NDST1, UQCRQ, PHOX2A, PITX3, EN1, FOXB1, TAL2, KAT2A, FZD6, EN2, GDF7, LMX1A |
| midbrain dopaminergic neuron differentiation | biological process | RYK, WNT9B, LRP6, NR4A2, LMX1A |
| midbrain morphogenesis | biological process | SOS1, FZD3, FZD6 |
| midbrain-hindbrain boundary development | biological process | FGF8, LRP6, EN1, GBX2 |
| midbrain-hindbrain boundary initiation | biological process | SSBP3 |
| midbrain-hindbrain boundary morphogenesis | biological process | HES1, GBX2 |
| middle ear morphogenesis | biological process | FGFR1, HOXA2, PRKRA, RPL38, NKX3-2, TSHZ1, MSX1, PRRX1, INSIG1, SIX1, SIX2, GSC, EYA1, EDN1, NAGLU, OSR2, INSIG2 |
| midgut development | biological process | CTNNB1, ALDH1A2, CPS1, ASS1, SMO, FOXF1 |
| milk ejection reflex | biological process | GJA1 |
| mineralocorticoid biosynthetic process | biological process | HSD3B1, HSD3B2, CYP21A2, CYP11B2 |
| mineralocorticoid receptor signaling pathway | biological process | JAK2 |
| minus-end-directed organelle transport along microtubule | biological process | RAB6A, BICD1, BICD2 |
| miRNA catabolic process | biological process | LIN28B, PARN, TENT4B, TUT4, DIS3L2, SND1, LIN28A |
| miRNA loading onto RISC involved in gene silencing by miRNA | biological process | DICER1, AGO4, ADAR, TARBP2, AGO3, AGO2, AGO1 |
| miRNA mediated inhibition of translation | biological process | STAT3, AGO4, AGO3, RBM4, AGO2, TNRC6B, ZFP36, TRIM71, TNRC6A, TNRC6C, EIF6, NOTCH4, AGO1 |
| miRNA metabolic process | biological process | DROSHA, AGO4, PRKRA, TARBP2, RAN, AGO2, TRIM71, DDX17, AGO1, TUT4, KHSRP, TUT7, LIN28A |
| miRNA transport | biological process | HNRNPA2B1, YBX1, TGFBR2 |
| mismatch repair | biological process | MSH4, MSH5, MLH1, PMS2, MLH3, PCNA, XPC, MSH2, RPA2, PMS1, RPA1, TDG, EXO1, MSH6, MUTYH, POLD2, ABL1, RPA3, LIG1, RNASEH2A, POLD4, TREX1, POLD1 |
| mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication | biological process | MCM9 |
| mitigation of host defenses by symbiont | biological process | KPNA6 |
| mitochondria-nucleus signaling pathway | biological process | SLC25A33 |
| mitochondrial acetyl-CoA biosynthetic process from pyruvate | biological process | MPC1, PDHA1, MPC2, PDHX, PDHB |
| mitochondrial alanyl-tRNA aminoacylation | biological process | AARS1, AARS2 |
| mitochondrial asparaginyl-tRNA aminoacylation | biological process | DARS2 |
| mitochondrial ATP synthesis coupled electron transport | biological process | NDUFB6, NDUFS2, NDUFA12, BID, NDUFV3 |
| mitochondrial ATP synthesis coupled proton transport | biological process | MT-ATP6, MT-ATP8, ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, DMAC2L, ATP5MC3, ATP5PF, ATP5F1E, ATP5PD, ATP5MC1, ATP5F1D, ATP5MC2, STOML2, ATP5MG, ATP5MF, ATP5ME, COX5B, CYC1 |
| mitochondrial calcium ion homeostasis | biological process | ANXA6, PDZD8, MAIP1, C19orf12, DISC1, SLC8A3, IMMT, SMDT1, MICU2, AFG3L2, MCUB, MICU1, LETM1, SLC8B1 |
| mitochondrial calcium ion transport | biological process | VDAC1, PMPCB, PARL, MAIP1, STOML2, PHB2, PMPCA, SLC8A3, SMDT1, MICU2, YME1L1, AFG3L2, MCUR1, BHLHA15, MCUB, MICU3, SPG7, MICU1, LETM1, SLC8B1, SLC25A23 |
| mitochondrial citrate transmembrane transport | biological process | SLC25A1 |
| mitochondrial cytochrome c oxidase assembly | biological process | COX17, TIMM21, COA8, COA1, SCO1, TACO1, COX16, BCS1L, PET100, COA4, COX20, COX18, SURF1, PET117, COA5, COX14, OXA1L, FASTKD3, SCO2 |
| mitochondrial depolarization | biological process | CASP1, CDKN2A, ATP5IF1, ABL1 |
| mitochondrial DNA metabolic process | biological process | PARP1, POLG2, SESN2, LONP1 |
| mitochondrial DNA repair | biological process | PARP1, MGME1, LIG3, PRIMPOL, TP53 |
| mitochondrial DNA replication | biological process | POLG, SSBP1, RRM2B, MGME1, POLG2, TEFM, PRIMPOL |
| mitochondrial double-strand break repair via homologous recombination | biological process | MRE11 |
| mitochondrial electron transport, cytochrome c to oxygen | biological process | CYCS, COX10, MT-CO1, MT-CO3, NDUFA4, COX7A2L, COX7C, COX5A, COX7B, AFG1L, COX6A1, COX6C, COX5B, COX6B1, COX8A, MT-CO2, COX4I1, COX6A2 |
| mitochondrial electron transport, NADH to ubiquinone | biological process | MT-ND4, NDUFC2, MT-ND5, NDUFA6, NDUFB9, NDUFA4, NDUFB5, NDUFS6, NDUFB6, NDUFAF1, NDUFC1, COQ9, NDUFS4, NDUFA8, NDUFB8, NDUFS2, NDUFB10, NDUFA1, NDUFA2, NDUFB1, NDUFS1, NDUFB4, NDUFA12, NDUFA5, NDUFAB1, NDUFA7, NDUFA11, NDUFC2-KCTD14, NDUFA3, NDUFV2, NDUFB11, NDUFA9, NDUFV3, NDUFB2, NDUFS8, NDUFB7, NDUFA10, MT-ND4L, MT-ND6, NDUFS5, NDUFS7, MT-ND1 |
| mitochondrial electron transport, succinate to ubiquinone | biological process | SDHD, SDHAF2, SDHC |
| mitochondrial electron transport, ubiquinol to cytochrome c | biological process | CYCS, MT-CYB, UQCRFS1, UQCRB, UQCRC2, UQCR11, MECP2, UQCRQ, UQCRHL, UQCRC1, UQCR10, CYC1, UQCRH |
| mitochondrial FAD transmembrane transport | biological process | SLC25A32 |
| mitochondrial fission | biological process | COX10, DNM1L, MFF, PRKN, MTFR1L, DNM3, OPA1, MX1, MIEF1, FIS1, MTFR1, MTFR2, MX2, MUL1, DNM1, GDAP1 |
| mitochondrial fragmentation involved in apoptotic process | biological process | BAX, DNM1L, MFF, BNIP3, CCAR2, FIS1, ATG3, VPS35 |
| mitochondrial fusion | biological process | BAX, BAK1, MIGA1, MFF, USP30, OPA1, MFN1, MIEF2, AFG3L2, MFN2, MIEF1, FIS1, CHCHD3, MIGA2, GDAP1 |
| mitochondrial genome maintenance | biological process | MEF2A, SLC25A4, SLC25A33, SLC25A36, MGME1, OPA1, MSTO1, TYMP, LONP1, MPV17 |
| mitochondrial glycyl-tRNA aminoacylation | biological process | GARS1 |
| mitochondrial L-ornithine transmembrane transport | biological process | SLC25A15, SLC25A2, SLC25A29 |
| mitochondrial large ribosomal subunit assembly | biological process | FASTKD2, DHX30 |
| mitochondrial manganese ion transmembrane transport | biological process | SLC39A8 |
| mitochondrial membrane fission | biological process | DNM1L, SLC25A46 |
| mitochondrial membrane fusion | biological process | RCC1L, MFN1 |
| mitochondrial membrane organization | biological process | TIMM50, MFN2 |
| mitochondrial mRNA catabolic process | biological process | SUPV3L1, PNPT1 |
| mitochondrial mRNA polyadenylation | biological process | PNPT1 |
| mitochondrial mRNA processing | biological process | TBRG4 |
| mitochondrial mRNA surveillance | biological process | SUPV3L1 |
| mitochondrial ncRNA surveillance | biological process | SUPV3L1 |
| mitochondrial nucleoid organization | biological process | CHCHD10 |
| mitochondrial outer membrane permeabilization | biological process | BLOC1S2, RTL10, BNIP3L, BID, BNIP3, RHOT2, RHOT1, EYA2 |
| mitochondrial outer membrane permeabilization involved in programmed cell death | biological process | PPIF, SPG7 |
| mitochondrial outer membrane translocase complex assembly | biological process | TOMM20, TOMM20L |
| mitochondrial protein catabolic process | biological process | AFG1L, BNIP3L, BNIP3, YME1L1 |
| mitochondrial protein processing | biological process | ATP23, OMA1, STOML2, YME1L1, AFG3L2 |
| mitochondrial proton-transporting ATP synthase complex assembly | biological process | ATP23, ATP5F1D, ATPAF1, TMEM70, FMC1, OXA1L |
| mitochondrial pyruvate transmembrane transport | biological process | MPC1, MPC2, MPC1L |
| mitochondrial respirasome assembly | biological process | COX7A2L, HIGD1A, RAB5IF, COX7A2, HIGD2A, COX7A1, HIGD1B |
| mitochondrial respiratory chain complex assembly | biological process | OMA1, SAMM50, AIFM1, IMMP2L, TFAM |
| mitochondrial respiratory chain complex I assembly | biological process | MT-ND4, NDUFC2, MT-ND5, NDUFA6, NUBPL, TIMM21, TIMMDC1, NDUFB9, NDUFB5, NDUFS6, NDUFB6, NDUFAF2, COA1, TMEM126B, NDUFAF1, NDUFC1, NDUFAF5, NDUFS4, NDUFA8, ACAD9, NDUFB8, NDUFAF7, TMEM126A, NDUFS2, NDUFB10, NDUFA1, NDUFA2, NDUFB1, ECSIT, NDUFS1, NDUFB4, AIFM1, NDUFA12, NDUFA5, BCS1L, NDUFAB1, NDUFA7, NDUFA11, DMAC2, NDUFA3, NDUFV2, NDUFB11, NDUFAF8, NDUFA9, DMAC1, NDUFV3, NDUFAF3, NDUFB2, NDUFS8, NDUFB7, NDUFA10, FOXRED1, OXA1L, MT-ND6, NDUFS5, NDUFAF6, NDUFS7, MT-ND1 |
| mitochondrial respiratory chain complex II assembly | biological process | SDHAF2, SDHAF3, SDHAF1 |
| mitochondrial respiratory chain complex III assembly | biological process | LYRM7, UQCRB, SLC25A33, UQCC1, BCS1L, UQCR10, UQCC2, TTC19, C12orf73 |
| mitochondrial ribosome assembly | biological process | MTERF3, MRPS2, MTERF4, MPV17L2 |
| mitochondrial RNA 3'-end processing | biological process | SUPV3L1, PNPT1 |
| mitochondrial RNA 5'-end processing | biological process | TRMT10C, PNPT1 |
| mitochondrial RNA catabolic process | biological process | PNPT1 |
| mitochondrial RNA metabolic process | biological process | FASTKD1 |
| mitochondrial RNA processing | biological process | FASTKD5, PNPT1 |
| mitochondrial RNA surveillance | biological process | SUPV3L1 |
| mitochondrial seryl-tRNA aminoacylation | biological process | SARS2 |
| mitochondrial threonyl-tRNA aminoacylation | biological process | TARS2 |
| mitochondrial transcription | biological process | TFB2M, SLC25A33, POLRMT, MTERF3, TEFM, MRPL12, FOXO3, TFAM, MTERF4, PPARGC1B |
| mitochondrial translation | biological process | MRPS14, MRPS15, MRPL47, MRPS35, MRPS11, MRPS21, MRPL16, MRPL43, PTCD3, MRPS17, MRPS18A, MRPL51, MRPS24, HARS1, IARS2, MRPS7, MRPL23, MRPS12, NDUFA7, MRPL57, MRPS16, GFM2, RARS2, MRPL52, MRPS2, MRPS34, CHCHD1, QRSL1, LARS2, GATB, GATC, MRPS6, NOA1 |
| mitochondrial translational elongation | biological process | MRPS14, DAP3, MRPS15, GFM1, MRPL20, MRPL47, MRPL17, MRPL22, MRPL3, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, MRPL16, MRPS23, MRPL14, MRPL43, PTCD3, MRPL46, MRPS17, MRPL49, MRPS30, MRPS18A, MRPL39, MRPL15, MRPL19, MRPL58, MRPL51, MRPS24, MRPL35, MRPL27, ERAL1, MRPS7, MRPS18C, MRPL10, MRPL48, MRPL40, MRPL37, MRPS33, MRPL11, MRPS28, MRPL33, MRPS26, MRPL23, MRPL38, MRPS12, MRPS25, MRPL54, MRPS27, MRPL57, AURKAIP1, MRPS16, MRPL21, MRPL55, MRPL41, GFM2, MRPL53, TSFM, MRPL34, MRPS31, TUFM, MRPL52, MRPL50, MRPL36, MRPS2, MRPS34, CHCHD1, MRPL12, GADD45GIP1, MRPL4, MRPL44, OXA1L, MRPL24, MRPL1, MRPL28, MRPS6, MRPL9 |
| mitochondrial translational initiation | biological process | MTIF3 |
| mitochondrial translational termination | biological process | MRPS14, DAP3, MRPS15, MRPL20, MRPL47, MRPL17, MRPL22, MRPL3, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, MRPL16, MRPS23, MRPL14, MRPL43, PTCD3, MRPL46, MRPS17, MRPL49, MRPS30, MRPS18A, MRPL39, MRPL15, MRPL19, MRPL58, MRPL51, MRPS24, MRPL35, MRPL27, ERAL1, MTRF1L, MRPS7, MRPS18C, MTRF1, MRPL10, MRRF, MRPL48, MRPL40, MRPL37, MRPS33, MRPL11, MRPS28, MRPL33, MRPS26, MRPL23, MRPL38, MRPS12, MRPS25, MRPL54, MRPS27, MRPL57, AURKAIP1, MRPS16, MRPL21, MRPL55, MRPL41, GFM2, MRPL53, MRPL34, MRPS31, MRPL52, MRPL50, MRPL36, MRPS2, MRPS34, CHCHD1, MRPL12, GADD45GIP1, MRPL4, MRPL44, OXA1L, MRPL24, MRPL1, MRPL28, MRPS6, MRPL9 |
| mitochondrial transmembrane transport | biological process | UCP3, SFXN1, UCP1, UCP2, SFXN3, SFXN2, SFXN5 |
| mitochondrial transport | biological process | HSP90AA1, TMEM14C, SLC25A13, FLVCR1, TMEM14B, UCP3, SLC25A46, MTX2, TMEM14A, UCP1, PSEN1, UCP2, SLC25A30, SLC25A24, SLC25A14, ABCB10, SLC25A10, STARD3, SLC25A32, SLC25A16 |
| mitochondrial tRNA 3'-end processing | biological process | TRNT1, TRMT10C, HSD17B10 |
| mitochondrial tRNA 3'-trailer cleavage, endonucleolytic | biological process | ELAC2 |
| mitochondrial tRNA 5'-end processing | biological process | TRMT10C, PRORP, HSD17B10 |
| mitochondrial tRNA methylation | biological process | TRMT5, TRMT10C, PRORP, TRMT61B, HSD17B10 |
| mitochondrial tRNA modification | biological process | CDK5RAP1, TRIT1 |
| mitochondrial tRNA processing | biological process | ELAC2, TRMT10C, PRORP, HSD17B10, TRMT10A |
| mitochondrial tRNA wobble uridine modification | biological process | MTO1 |
| mitochondrion distribution | biological process | MEF2A, TRAK2, MTM1, TRAK1, MSTO1, ATCAY, HAP1 |
| mitochondrion localization | biological process | MARK2, MFN1, MFN2, HDAC6, BRAT1, MUL1, LRRK2 |
| mitochondrion morphogenesis | biological process | BAX, PANK2, DNM1L, NUBPL, NDUFS6, SSBP1, MTM1, OPA3, SUPV3L1, MFF, MYH14, POLG2, OPA1, FEZ1, PID1, IMMT, CERT1, FIS1, PNPT1, WASF1, BCL2L1 |
| mitochondrion organization | biological process | NOS3, TERT, PARP1, PARK7, CYCS, COX10, ATP5F1B, SSBP1, FXN, MTERF1, SIRT5, RAB29, RAB38, TFB2M, CHCHD2, MAN2A1, ATAD3B, SLC25A33, ATAD3A, OMA1, SIRT4, HAX1, HTRA2, PRKN, HCFC1, AFG1L, SLC25A46, SLC25A36, PPARGC1A, RAB32, VPS13C, XAF1, POLG2, STOML2, FANCG, OPA1, TMEM11, PHB2, POLRMT, CAV2, SQSTM1, WDR81, CEP89, PINK1, BCS1L, NIPSNAP2, PRDX3, VPS13D, MIEF2, YME1L1, SHARPIN, AFG3L2, CXADR, RHOT2, MSTO1, ATP7A, RHOT1, MTFR1, MTFR2, TFB1M, EPAS1, ESRRA, P2RX7, HSD17B10, HMGCL, GABPA, TRAFD1, LIG3, CLUH, CDK5, CAMKMT, SESN2, PPRC1, SPG7, TFAM, CHCHD10, ALAS1, ATAD3C, LONP1, GABPB1, LRRK2, GDAP1 |
| mitochondrion to lysosome transport | biological process | PRKN, PINK1, VPS35 |
| mitochondrion transport along microtubule | biological process | KIF1B, LRPPRC, MAP1S, RHOT2, RHOT1, UBB, MAP1B |
| mitochondrion-endoplasmic reticulum membrane tethering | biological process | PDZD8, PSEN2, PACS2 |
| mitophagy | biological process | CDKN2A, FUNDC1, RB1CC1, MAP1LC3A, CTSK, MARK2, PRKN, SLC25A46, PPARGC1A, ATG12, USP30, FUNDC2, ATG5, SQSTM1, PINK1, WDR45, ATG2B, BNIP3, WIPI2, BECN1, WDR45B, FIS1, ATG9A, GABARAPL1, ATG3, GABARAP, GABARAPL2, WIPI1, MAP1LC3B, FBXO7, ATG2A, AMBRA1, ATG13, ATG9B, MAP1LC3C |
| mitophagy | biological process | PRKN, PHB2, SQSTM1, BECN1, MAP1LC3B, AMBRA1, ATG13 |
| mitophagy in response to mitochondrial depolarization | biological process | PGK2, PIK3CA, DPF3, ANXA5, HUWE1, PRKN, PINK1, TOMM7, HDAC6, CDC37 |
| mitotic cell cycle | biological process | CDK1, CCNB1, XRCC2, TADA3, OFD1, CENPE, IK, ABRAXAS2, TUBGCP4, CETN2, E2F4, NUP88, MIS12, PLK2, PPP1R12A, ZW10, CDC23, USP16, USP3, CIT, NDC80, ESPL1, WAPL, SETDB2, KIF15, NUDT15, SMC3, AKAP8, BUB1B, RECQL5, YEATS4, NUP62, CETN1, CENPT, CHFR, MASTL, SUGT1, DCTN3, ORC1, TUBB2A, NEK3, GEM, ARPP19, MCPH1, SNX33, ZNF830, TUBE1, TPX2, CENPF, CDC6, MEN1, SNX9, TUBB, PLK1, TUBGCP3, RAN, TUBB4B, ANAPC11, CDC14B, TUBG1, RRM1, CLIP1, PBRM1, UBA3, ABL1, PPP2R2D, SKA2, JTB, LATS1, NEK4, CLTCL1, CLTC, TFDP2, CENPW, TUBA1C, TUBB4A, PPP5C, CENPC, TUBA3E, ZNRD2, SRSF2, TUBGCP5, TBCD, CEP250, CDH13, POLE, TUBB8, PKMYT1, PRDM5, WDHD1, SKA1, SNX18, TUBGCP2, TUBB6, TTYH1, PLK3, TUBAL3, CDCA5, TUBGCP6, EML4, RGS14, CCNO, NCAPD2, DIS3L2, KIF18B, TUBG2, FBXL7, CDK11B, CDC25B, CDK11A, NUP214, NEK2, KIF11, KIF22, RNF2, CDC5L |
| mitotic cell cycle arrest | biological process | NKX3-1, MCPH1, GADD45A, CDC14B, CDKN1B, PNPT1, RGCC, DUSP1, CDKN1A, E4F1, GADD45GIP1, MAGI2, TP53 |
| mitotic cell cycle checkpoint | biological process | TGFB1, RB1, NBN, PLK2, ZW10, MAP3K20, BUB1, BUB1B, CHFR, ZWINT, ZWILCH, RAD17, CDKN2B, DCLRE1B, MAD2L1, DLG1, INTS3, NABP1, MAD1L1, HUS1, TTK, BCL2L1, HRAS, NABP2, PLK3, WNT9A, KNTC1 |
| mitotic cell cycle phase transition | biological process | CKS1B, CCNJL, CCNI, CCND1, CCNE1, CCNG1, CCNG2, CCNF, CCNE2, CCNP, LZTS1, CCNO, CKS2, CCND3, CCNB3 |
| mitotic centrosome separation | biological process | KIF3B, NUP62, NDE1, KIF11 |
| mitotic chromosome condensation | biological process | NUSAP1, AKAP8, NCAPD3, NCAPH2, NCAPH, NCAPG, CHMP1A, TTN, NIPBL, SMC4, TENT4A, CDCA5, NCAPD2, AKAP8L, SMC2 |
| mitotic chromosome movement towards spindle pole | biological process | KATNB1, CENPE, DLGAP5 |
| mitotic cleavage furrow ingression | biological process | ARF1 |
| mitotic cytokinesis | biological process | USP8, RASA1, EFHC1, KIF20A, MYH10, NUSAP1, ANK3, CEP55, CIT, ESPL1, ROCK2, ARL3, SPTBN1, CHMP4B, PRC1, STMN1, RAB35, ANLN, UNC119, SNX33, BBS4, ROCK1, MITD1, SNX9, PLK1, CKAP2, SON, APC, MAP9, ECT2, JTB, PDCD6IP, CUL7, ZFYVE26, LZTS2, KIF4A, STAMBP, TTC19, RTKN, SNX18, KIF23, RHOC, CENPA, KIF4B, INCENP, SPAST |
| mitotic cytokinesis checkpoint | biological process | CHMP4C, AURKB |
| mitotic cytokinetic process | biological process | CNTROB |
| mitotic DNA damage checkpoint | biological process | ZNF830 |
| mitotic DNA integrity checkpoint | biological process | TOP2A, TOP2B |
| mitotic DNA replication | biological process | MCM6 |
| mitotic DNA replication checkpoint | biological process | NAE1, ORC1, TOPBP1, ZNF830, RAD17, CDC6, HUS1, CLSPN, HUS1B |
| mitotic DNA replication initiation | biological process | MCM3, MCM4, MCM2, POLA1 |
| mitotic DNA replication preinitiation complex assembly | biological process | CDC45 |
| mitotic DNA replication termination | biological process | RTF2 |
| mitotic G1 DNA damage checkpoint | biological process | TP53, TP63, RPA2, RPS27L, CCND1, RFWD3, DGKZ, GIGYF2, FBXO31 |
| mitotic G1/S transition checkpoint | biological process | PLK3 |
| mitotic G2 DNA damage checkpoint | biological process | CDK1, NBN, CCNA2, TRIM39, FOXN3, CDK5RAP3, TAOK2, SYF2, TOPBP1, HMGA2, TAOK3, MRE11, TAOK1, CLSPN, CDKN1A, BLM, FOXO4, MRNIP, BRSK1, DONSON |
| mitotic G2/M transition checkpoint | biological process | CDK5RAP3 |
| mitotic metaphase plate congression | biological process | CCNB1, CENPE, CHMP2A, RAB11A, ZW10, CEP55, CHMP5, CDC23, SPDL1, VPS4B, CHMP4A, NUP62, KIF14, CHMP4B, KIFC1, CHMP1A, PIBF1, CHMP6, SEH1L, ANKRD53, BOD1, BECN1, KIF18A, DCTN2, PDCD6IP, RRS1, CHMP4C, CDCA8, CHMP7, PSRC1, CDCA5, PINX1, CHMP3, KIF22, CHMP1B |
| mitotic nuclear division | biological process | AURKC, BIRC5, CCNB2, CDK1, CCNB1, WEE1, CDC25A, CDC25C, NR3C1, BRSK2, HGF, CDC20, TUBB3, 39326, RNF8, DYNLT1, KATNB1, WASL, CCNA2, CCNA1 |
| mitotic nuclear division | biological process | USP16, SMPD3 |
| mitotic nuclear envelope disassembly | biological process | CCNB2, CDK1, CCNB1, CNEP1R1, LPIN1, PRKCB, PLK1, CTDNEP1, NEK9, NEK6 |
| mitotic nuclear envelope reassembly | biological process | EMD, PPP2CA, PPP2R2A, REEP4, ANKLE2, PPP2R1A, REEP3 |
| mitotic recombination | biological process | ERCC1, TOP2A, DMC1, RAD52, RAD54B |
| mitotic recombination-dependent replication fork processing | biological process | BRCA2 |
| mitotic sister chromatid biorientation | biological process | BOD1 |
| mitotic sister chromatid cohesion | biological process | POGZ, DSCC1, NAA50, MAU2, NIPBL, PDS5A, PDS5B, CHTF8, SMC1A, CDCA5 |
| mitotic sister chromatid cohesion, centromeric | biological process | SGO1, NAA50, BOD1 |
| mitotic sister chromatid segregation | biological process | NUSAP1, MIS12, ZW10, BUB3, DSN1, NDC80, ESPL1, KLHL22, ZNF207, WRAP73, ZWINT, HIRA, KIFC1, SGO1, PLK1, MAD2L1, RAN, TUBG1, KIF18A, MSTO1, SMC1A, NSL1, SMC4, KNSTRN, SGO2, CDCA8, INO80, KIF18B, TUBG2, KIF25, NCAPG2, INCENP, NEK2, CENPK |
| mitotic sister chromatid separation | biological process | NCAPH2, DIS3L2, PPP2R1A |
| mitotic spindle assembly | biological process | BIRC5, KIF3B, OFD1, ABRAXAS2, BCCIP, KIF2A, RAB11A, ARHGEF10, SMC3, ZNF207, WRAP73, KIFC1, ABRAXAS1, PIBF1, TPX2, MZT1, MAP9, STAG2, STAG1, MSTO1, SMC1A, CLASP2, SPICE1, AAAS, MISP, GOLGA2, CLASP1, CEP192, NEK2, KIF11 |
| mitotic spindle assembly checkpoint | biological process | ATM, IK, ZW10, BUB3, SPDL1, BUB1, BUB1B, KLHL22, ZNF207, TRIP13, CENPF, PLK1, MAD2L1, APC, MAD1L1, TTK, MAD2L2, TPR, AURKB, PSMG2 |
| mitotic spindle checkpoint | biological process | CSNK2A2 |
| mitotic spindle disassembly | biological process | SPAST |
| mitotic spindle elongation | biological process | PRC1, KIF23 |
| mitotic spindle microtubule depolymerization | biological process | CCSAP |
| mitotic spindle midzone assembly | biological process | AURKC, PRC1, KIF4A, KIF23, KIF4B, AURKB |
| mitotic spindle organization | biological process | CCNB1, KIF3B, DYNC1H1, CENPE, EFHC1, BCCIP, KIF2A, GPSM2, PLK2, SBDS, NDC80, TACC1, TNKS, MAP4, TACC2, STMN1, TACC3, WDR62, MECP2, RAN, TUBG1, TTK, CEP126, DCTN2, CKAP5, RCC1, TBCE, EML1, CLASP2, KIF4A, PCNT, STIL, SPC25, SUN2, TUBG2, KIF4B, CLASP1, AURKB, KIF11, NUF2, CENPH |
| mitotic telomere maintenance via semi-conservative replication | biological process | PCNA, RTEL1 |
| mitral valve development | biological process | GJA5 |
| mitral valve formation | biological process | DCHS1, NOTCH1, ZFPM1 |
| mitral valve morphogenesis | biological process | EFNA1, ACVR1, DCHS1, BMPR1A, SMAD6, TWIST1, SOX4 |
| Mo-molybdopterin cofactor biosynthetic process | biological process | MOCS3, MOCOS, MOCS2, GPHN, NFS1 |
| modification by virus of host mRNA processing | biological process | CPSF4, PABPN1 |
| modification of dendritic spine | biological process | SYNPO, ARHGAP44 |
| modification of postsynaptic actin cytoskeleton | biological process | MYH10, WASF3, PFN2, CTNNA2, WASF1 |
| modification of postsynaptic structure | biological process | STAU1, ARHGAP44 |
| modification of synaptic structure | biological process | REST, CYFIP1 |
| modification of synaptic structure, modulating synaptic transmission | biological process | BAIAP2 |
| modification-dependent protein catabolic process | biological process | RPS27A, CHFR, UBA7, NEDD8, ISG15, UBC, UBE2L6, UBA52, UBB |
| modulation by host of viral genome replication | biological process | IFI27 |
| modulation by host of viral process | biological process | HSPA8 |
| modulation by host of viral RNA genome replication | biological process | FMR1, VAPB, FBXL2 |
| modulation by host of viral transcription | biological process | PSMC3 |
| modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade | biological process | TNIP1 |
| modulation by virus of host cellular process | biological process | KPNA4, KPNA2, KPNA5, KPNA3, KPNA1 |
| modulation by virus of host process | biological process | VAPB, RRAGA, CD209, HIPK2, DAG1 |
| modulation of age-related behavioral decline | biological process | PRNP, CCL11, PICALM, DKK1, PSEN1, GRM5, AGER |
| modulation of chemical synaptic transmission | biological process | JAK2, AKAP12, BAIAP2, DGKE, NPTN, NRG3, NLGN4X, PPP1R9B, STAU1, PTPRA, PSMC5, EIF4EBP2, DGKB, PRKN, BCR, ABR, NTF4, NLGN2, AKAP7, WNT3A, LRFN2, NTNG1, EPHB1, PACSIN2, CACNA1A, PXK, NLGN4Y, SRGN, GRIA2, GRIN2C, ADCY8, PPP3CA, GRIK3, GRIK5, NTNG2, CX3CR1, GRIN2B, PPP1R9A, GRIN3A, LRRC4, GRID2, PRKAR2B, CDH11, GRIA3, PTPRS, GRIK4, SLC4A8, NTF3, PRKAR1B, BACE1, GRIN2A, RGS14, GRIN3B, CSPG5, DNM1, DRD2, GRIA1, P2RX3, GRID1, CACNA1B, BTBD9, GRIN2D, GRIK1, GRIK2, RELN, GPER1 |
| modulation of excitatory postsynaptic potential | biological process | CHRNA7, SLC8A3, TMEM108, ZMYND8, SH3GL1, SLC8A2 |
| modulation of process of other organism | biological process | CAMP, POMC, GALP |
| molybdenum incorporation into molybdenum-molybdopterin complex | biological process | GPHN |
| molybdopterin cofactor biosynthetic process | biological process | MOCS3, MOCOS, MOCS2, GPHN, NFS1 |
| molybdopterin cofactor metabolic process | biological process | MOCOS |
| monoacylglycerol biosynthetic process | biological process | DGAT2, DGAT1, PLA2G4A, DGAT2L6, MOGAT2, MOGAT3 |
| monoacylglycerol catabolic process | biological process | ABHD12B, ABHD12, ABHD16A, ABHD16B, ABHD6, MGLL, FAAH |
| monoamine transport | biological process | PICK1, SLC6A2, SLC6A4, SLC18A2, SLC6A3, SLC22A1, SLC22A3 |
| monocarboxylic acid metabolic process | biological process | CYP1A2, GLYAT, CYP2C9 |
| monocarboxylic acid transport | biological process | SLC16A7, SLC5A8, SLC16A5, SLC16A14, SLC16A10, SLC16A9, SLC16A13, SLC16A8, SLC16A1, SLC16A6, SLC16A12, SLC16A11 |
| monocyte activation | biological process | SPACA3, CSF1, FOXP1, MT1G, ADAM9, HYAL2, AZU1 |
| monocyte activation involved in immune response | biological process | DYSF |
| monocyte aggregation | biological process | IL1B, CD44, BMP7, CD47 |
| monocyte chemotaxis | biological process | IL6, IL6R, FLT1, S100A12, CCL5, CX3CL1, CCL16, CCL20, CCL8, PDGFB, CCL1, RPS19, CCL14, CCL3, ANXA1, CCL11, CCL22, DEFB104A, CCL26, CCL18, CCL23, CCL19, CALCA, PTPRO, CCL3L1, TNFRSF11A, CCL7, CCL17, CCL21, CCL2, CCL15 |
| monocyte differentiation | biological process | VEGFA, BMP4, PPARG, PIR, SP3, MEF2C, PDE1B, FASN, MT1G, THOC5, IFI16, MYH9, IL31RA, PDE2A, CSF1R |
| monocyte extravasation | biological process | CD47, JAML, PECAM1 |
| monocyte homeostasis | biological process | SH2B3, MPL |
| mononuclear cell migration | biological process | PLG |
| mononuclear cell proliferation | biological process | TGFB1, ACE |
| monopolar spindle attachment to meiosis I kinetochore | biological process | CENPC |
| monosaccharide metabolic process | biological process | AKR1B1, GAL3ST3, FUOM |
| monoterpenoid metabolic process | biological process | CYP1A2, CYP2C19, CYP2E1, CYP2D6, CYP2C9 |
| monoubiquitinated histone H2A deubiquitination | biological process | USP16, ASXL1, MYSM1, BAP1 |
| monoubiquitinated protein deubiquitination | biological process | USP1, USP47, ATXN3, USP7, USP15, BAP1 |
| monovalent inorganic cation transport | biological process | ASIC1, ASIC2, TMEM38B, FXYD4, SLC9B2, P2RX3, RHAG |
| morphogenesis of a branching epithelium | biological process | SOX9, SOX10, BTBD7 |
| morphogenesis of a branching structure | biological process | TGFB1, TDGF1, PRDM1, NOTCH4, FOXF1, COL16A1, COL19A1, IHH, COL13A1 |
| morphogenesis of a polarized epithelium | biological process | TP63, TRAF3IP1, AHI1, ACTG1, LAMA3, LAMA5 |
| morphogenesis of an epithelial fold | biological process | EGFR, HOXD13, GDF7 |
| morphogenesis of an epithelial sheet | biological process | LIN7C, HOXB4, SRF, DAG1, ARHGAP12, HOXB2, JAG1 |
| morphogenesis of an epithelium | biological process | CA2, HOXA5, SLC9A3R1, CRYGS, KRT6A, CA9, FREM2, TIMELESS, FRAS1, TBX5, VCL, SERPINB5, KRT17, HOXB13, DAG1, GLI2 |
| morphogenesis of embryonic epithelium | biological process | FGFR2, CTNNB1, ALDH1A2, GRSF1, TGFB1I1, PDX1, SCRIB, VEGFC, KDF1, PCDH8, JAG2, LAMA5 |
| motile cilium assembly | biological process | AKAP4, LRRC6, DNAAF1, IFT57, E2F4, FOXJ1, SPATA6, ATMIN, DMD, BBS5, BBOF1, DNAAF3, INTU, RSPH9, ZMYND10, RSPH6A, CFAP221, CCDC40, CC2D2A |
| motogenic signaling involved in postnatal olfactory bulb interneuron migration | biological process | FGFR1 |
| motor behavior | biological process | ADARB1, MFSD2A, ATP1B2 |
| motor learning | biological process | TACO1, DKK1, GPR88, ADGRB3, EN1 |
| motor neuron apoptotic process | biological process | FAS, ADARB1, FADD |
| motor neuron axon guidance | biological process | ERBB2, SEMA3A, FGF8, CHN1, HOXA2, LHX3, SLIT1, RHOG, NTN1, LAMC2, LHX1, RHOBTB3, RAC1, RNF165, EGR2, RAC2, MYCBP2, ALCAM, EPHA4, PLXNA4, TMEFF1, EGFLAM, CDK5, TMEFF2, NRP1, NTN5, AGRN, NTN3, LHX4, SLIT2 |
| motor neuron migration | biological process | NRP1 |
| movement of cell or subcellular component | biological process | IFNG, CXCL8, ANOS1, PTGS2, HSPB1, VIM, STAT3, PLAUR, AKAP4, IGF1, FPR1, ARHGDIA, CD9, ACTB, DNAH9, TPM1, WASL, MAPK14 |
| mRNA 3'-end processing | biological process | SRSF4, SRSF9, SRSF6, ZC3H11A, CSTF2, CPSF2, NUDT21, PAPOLA, NCBP2, CSTF1, SARNP, RPRD2, THOC3, CPSF4, DDX39B, THOC7, THOC1, CDC40, PCF11, SLU7, CPSF3, CASC3, NCBP1, U2AF1L4, SRSF3, RBM8A, ALYREF, POLDIP3, DDX39A, SRSF11, SRSF7, CPSF7, THOC2, CHTOP, THOC5, MAGOHB, UPF3B, CSTF3, ZC3H3, RPRD1A, U2AF1, SRSF2, CPSF1, RPRD1B, SRRM1, U2AF2, PABPN1, THOC6, WDR33, EIF4A3, SYMPK, SRSF5, CLP1 |
| mRNA 3'-end processing by stem-loop binding and cleavage | biological process | CPSF2, LSM11, CPSF3, ZNF473, SLBP |
| mRNA 3'-splice site recognition | biological process | SLU7, SF3A1, ISY1, SF3A3, SF1, SF3A2 |
| mRNA 5'-splice site recognition | biological process | SRSF12, PSIP1, SNRPC, SFSWAP, PRPF39 |
| mRNA alternative polyadenylation | biological process | NUDT21, VIRMA, CPSF7, CPSF6 |
| mRNA catabolic process | biological process | NANOS2, AGO4, PARN, DCP2, AGO3, CNOT10, DXO, NUDT16, CNOT9, NUDT12, RIDA, ERN1, RNH1, ZFP36L2, PNPT1, ZFP36, LSM6, ZFP36L1, YTHDF2, LSM2, DIS3L2, ZC3H12D, KHSRP, METTL16, ZHX2, HSPA1A, HSPA1B |
| mRNA cis splicing, via spliceosome | biological process | NCBP2, CWC15, SRSF12, SRSF8, RBM22, WBP11, RBM4B, NCBP1, SRSF3, WBP4, PRPF40A, SRSF7, RBM4, RBM19, SRSF2, DCPS, SART1, CACTIN, SRSF5 |
| mRNA cleavage | biological process | POLR1H, CPSF2, PCF11, CPSF3, RNASE4, ERN1, POLR2I, CSTF3 |
| mRNA cleavage involved in mRNA processing | biological process | ERN1 |
| mRNA destabilization | biological process | PUM1, YTHDF1, HNRNPR, MEX3D, YTHDF3, ROCK2, ROCK1, RIDA, CNOT6L, YTHDF2, RBM24, GIGYF2, METTL16 |
| mRNA export from nucleus | biological process | DDX25, SRSF4, SRSF9, SRSF6, RBMX2, AGFG1, NXF2, ZC3H11A, NUP93, UPF2, CPSF2, NCBP2, NUP37, NUP88, NUP85, ENY2, DDX19B, NUP107, SARNP, NUP43, POM121, THOC3, YTHDC1, CPSF4, DDX39B, THOC7, NUP35, THOC1, NUP58, CDC40, SEC13, NUP205, NUP50, SLU7, HNRNPA2B1, NUP62, EIF5A, CPSF3, CASC3, NCBP1, U2AF1L4, NUP155, UPF1, FYTTD1, NUP153, SRSF3, RBM8A, MCM3AP, RAE1, SMG7, SEH1L, SMG6, ALYREF, POLDIP3, DDX39A, EIF4E, SMG1, NXT1, SRSF11, SRSF7, GLE1, THOC2, NUP133, CHTOP, SLBP, THOC5, MAGOHB, UPF3B, NUP54, NXF1, TPR, RANBP2, NUP98, RBM15B, U2AF1, SRSF2, CPSF1, SRRM1, AAAS, U2AF2, HHEX, THOC6, SMG5, NUP210, WDR33, EIF4A3, SYMPK, NUP188, ALKBH5, NUP42, NUP214, NUP160, SRSF5 |
| mRNA export from nucleus in response to heat stress | biological process | POLR2D, TPR |
| mRNA localization resulting in posttranscriptional regulation of gene expression | biological process | MEX3D, ZNF385A |
| mRNA metabolic process | biological process | PABPC3, HNRNPU, CEBPG, PCBP3, PCBP2, TBRG4 |
| mRNA methylation | biological process | NSUN2, VIRMA, WTAP, ZC3H13, TRMT61A, TRMT10C, TRMT61B, TRMT6, CBLL1, CMTR1, METTL16, PCIF1 |
| mRNA modification | biological process | A1CF, APOBEC1, APOBEC2 |
| mRNA polyadenylation | biological process | APP, PABPC1, PABPC1L, CSTF2, TUT1, CPSF2, NUDT21, PAPOLA, GRSF1, MTPAP, PCF11, PAF1, CPSF3, AHCYL1, PAPOLB, CDC73, TENT2, PAPOLG, SCAF8, CSTF3, TENT4B, SSU72, CPSF1, LEO1, WDR33, SYMPK, CLP1 |
| mRNA processing | biological process | BRDT, PABPC1, C1QBP, KHDRBS1, XAB2, RBMY1A1, HNRNPL, SRSF4, SRSF9, SRSF6, RBMX, TCERG1, RBFOX2, ZRANB2, HSPA8, CSTF2, HNRNPF, SUPT4H1, HNRNPU, IK, HNRNPA0, PAN3, FAM172A, DDX1, PPIL3, TUT1, CPSF2, LSM1, PLRG1, NUDT21, KIN, RNGTT, SNRNP70, PAPOLA, HNRNPM, NCBP2, LSM3, ADARB1, CSTF1, CIR1, SUGP2, CTNNBL1, DDX47, CWC15, HNRNPR, SF3B1, HNRNPA1, HNRNPA3, TXNL4A, GRSF1, VIRMA, DDX46, FASTKD5, CELF5, SRSF12, THOC3, YTHDC1, SRSF8, A1CF, RBM22, PRPF19, STRAP, CPSF4, HNRNPC, SFPQ, MTREX, RBM25, MFAP1, RBM10, DDX39B, FRG1, SNRNP35, THOC7, SNIP1, SNRNP40, THOC1, SCAF1, MTPAP, TTF2, SRRM2, WBP11, SYNCRIP, CDC40, PCF11, SNRPB2, HNRNPH3, ADAR, WTAP, ARL6IP4, ESRP1, PRPF18, DDX23, SNRNP25, SAP18, SLU7, HNRNPA2B1, BUD31, LSM11, ZC3H13, RBBP6, RBM4B, CWC25, CPSF3, CASC3, PRPF6, TRA2B, NCBP1, SART3, RPUSD3, PHF5A, KHDC4, ZCRB1, U2AF1L4, PRPF31, SRPK1, XRN2, PPARGC1A, LUC7L3, YBX1, SRPK2, IWS1, PAPOLB, ACIN1, ECD, SYF2, SNU13, SNRPE, PPP1R8, SF3B2, TRA2A, PAN2, MBNL1, RBM28, DHX15, RNMT, SRSF3, RNASEL, RBM39, NONO, PRPF38A, SNRN |
| mRNA pseudouridine synthesis | biological process | DKC1, TRUB1, PUS3, PUS7 |
| mRNA splice site selection | biological process | SRSF9, SRSF6, CELF5, YTHDC1, LUC7L2, SETX, KHDC4, LUC7L3, CELF4, LUC7L, PUF60, CELF2, CELF6, NOL3, SRSF5 |
| mRNA splicing, via endonucleolytic cleavage and ligation | biological process | ERN1 |
| mRNA splicing, via spliceosome | biological process | SNRPN, PABPC1, XAB2, HNRNPL, SRSF4, SRSF9, SRSF6, RBMX2, RBMX, HSPA8, CSTF2, FUS, HNRNPF, HNRNPU, IK, HNRNPA0, CWC27, PPIL3, CPSF2, PLRG1, NUDT21, SNRNP70, PAPOLA, HNRNPM, NCBP2, POLR2F, LSM3, CSTF1, DHX40, CTNNBL1, CWC15, NOVA2, HNRNPR, SF3B1, DNAJC8, HNRNPA1, HNRNPA3, TXNL4A, CWF19L1, DDX46, PSPC1, YTHDC1, RBM22, PRPF19, CPSF4, HNRNPC, SFPQ, MTREX, MFAP1, POLR2G, RBM10, DDX39B, HNRNPD, FRG1, SNRNP35, SNIP1, SNRNP40, SRRM2, WBP11, HTATSF1, SYNCRIP, CDC40, PCF11, SNRPB2, HNRNPH3, GTF2F1, DDX23, SNRNP25, SLU7, HNRNPA2B1, BUD31, PCBP1, CWC25, CPSF3, CASC3, PRPF6, SNRPC, TRA2B, NCBP1, ELAVL2, SART3, PHF5A, ZCRB1, U2AF1L4, PRPF31, POLR2B, YBX1, CWF19L2, CHERP, CCAR1, POLR2D, SYF2, SNU13, SNRPE, SF3B2, TRA2A, DHX15, SRSF3, NONO, PRPF38A, SNRNP27, GEMIN6, RBM8A, U2SURP, WBP4, SNRPB, HNRNPH2, DDX41, DBR1, CD2BP2, ALYREF, GEMIN5, RAVER2, DDX39A, AQR, PRPF40A, POLR2J, SNRPD1, POLR2L, RSRC1, SRRT, SF3B6, PRPF3, POLR2E, SNRPD2, SRSF11, SRSF7, SUGP1, CPSF7, PNN, PUF60, BCAS2, HNRNPH1, SNRPG, SMU1, PRPF8, POLR2K, USP39, M |
| mRNA stabilization | biological process | E2F1, MTOR, PABPC1, GDNF, FUS, HNRNPU, PAIP1, HNRNPD, TENT5C, RBM46, TENT5A, YBX1, TAF15, MEIOC, TENT5D, LARP1, SLC11A1, RBM24, TENT5B, AXIN2, THRAP3, APOBEC1 |
| mRNA transcription | biological process | HSF1, PPARD, EEF1D, EREG, HIPK3, TP53 |
| mRNA transcription from RNA polymerase II promoter | biological process | HIF1A, TFCP2, HNRNPD, ATF4, SREBF1, SRF, FOXE3, C5AR1, ZBTB1 |
| mRNA transport | biological process | FMR1, DDX25, AGFG1, NXF2, ZC3H11A, NUP93, SENP2, CETN2, NCBP2, NUP37, NUP88, NUP85, ENY2, IGF2BP2, HNRNPA1, NUP107, SARNP, NUP43, POM121, THOC3, DDX39B, THOC7, NUP35, THOC1, NUP58, XPO1, SEC13, NUP205, NUP50, TNKS, HNRNPA2B1, NUP62, EIF5A, EIF5A2, UPF3A, CASC3, NCBP1, NUP155, PCID2, FYTTD1, IWS1, NUP153, SRSF3, RBM8A, MCM3AP, SEH1L, ALYREF, POLDIP3, CETN3, LRPPRC, SRSF7, GLE1, THOC2, NUP133, CHTOP, SLBP, AHCTF1, NPIPA1, THOC5, BICD2, MAGOHB, UPF3B, NCBP3, NUP54, QKI, NXT2, NXF1, G3BP2, TPR, ZFP36, RANBP2, NUP98, ZFP36L1, ZC3H3, MX2, IGF2BP3, NUTF2, MYO1C, AAAS, THOC6, PARP11, NUP210, EIF4A3, MVP, KHSRP, IGF2BP1, NUP188, NUP42, NUP214, NUP160, LUZP4 |
| mucociliary clearance | biological process | STARD7 |
| mucosal immune response | biological process | FFAR3, CD160, OTUD7B |
| mucosal-associated lymphoid tissue development | biological process | NKX2-3 |
| mucus secretion | biological process | VAMP8, AGR2, VAMP3 |
| Mullerian duct regression | biological process | AMH, AMHR2, BMPR1A, SMAD5 |
| multi-ciliated epithelial cell differentiation | biological process | E2F4, DEUP1, CCNO |
| multi-organism intercellular transport | biological process | RAB7A |
| multi-organism membrane organization | biological process | FCHSD2, PI4KA |
| multicellular organism aging | biological process | NR5A1, ERCC1, TP63, NDUFS6, SERP1, SEC63, CTSV, CRYAB, SLC1A2, DDC, RNF165, HYAL2, TH, EDN1, COMP |
| multicellular organism development | biological process | EGFR, TNF, PRM1, TP53, VDR, LIF, VEGFA, TNFRSF1B, DAZ2, TSSK4, DAZ4, CATSPER1, CATSPER2, TSSK6, DAZ1, NDRG2, IGF2, PRM2, FLT1, AKT1, KDR, SOX3, GSK3B, NODAL, RNF17, DMRT1, GNRH2, SEMA7A, GNRH1, TNP1, PAEP, BMP7, GNRHR, GPX4, LEPR, PGF, TNP2, SEMA3A, ODF2, PIWIL2, DAZL, PIWIL1, RTL1, BMP4, NANOS2, TSPY1, SLC7A5, ATR, PDCD1, SOHLH1, TXNDC8, DPY19L2, EBF2, DDX4, DAZ3, FGF17, MAK, OTX1, SOX2, FGF8, MEF2A, EMX1, MCL1, SHH, TAF7L, H1FNT, TXNDC2, PLCZ1, NME8, SPATA9, SPATA16, SPRY4, FLRT3, DDX25, RNF114, NTRK1, FGF3, FGF9, CREM, KIF26B, CATSPER4, PIWIL4, CATSPER3, BOLL, DYNC2H1, TDRD9, TCP11, GMCL1, MAEL, SLC26A8, MOV10L1, TP63, SOHLH2, WIPF3, AGFG1, NANOS3, UTP14C, PIWIL3, NLRP14, TNFRSF25, NXF2, CECR1, SHTN1, SEMA3E, SHOX, HOXA3, GADD45B, RYK, HOXD13, RPS4X, HNRNPU, BEX3, ROR1, CENPE, IKZF1, CAMK2B, NNAT, ISLR2, DZIP1, SIAH1, SEMA6D, SHROOM3, DDX1, OVOL2, BCL11A, RAB18, NUMBL, KIF2A, HOXD8, PAX7, HOXA6, NME5, ISL1, TLE1, DPYSL2, TBPL2, LCLAT1, CCBE1, PHF3, CUSTOS, OLFM1, STK36, DRG1, CNOT1, HACD1, FZD9, DIAPH2, NK |
| multicellular organism growth | biological process | BRCA2, GNAS, ERCC1, ERCC2, FGFR2, XPA, MTOR, CDC42, PTPN11, SOS1, XRCC2, NDUFS6, ADARB1, RARB, TNS2, FLVCR1, ZMPSTE24, HOXA5, ATRX, ERCC6, RBBP6, PLEKHA1, ETNK2, SLC1A2, ARID5B, TARBP2, SELENOM, CLIC4, TMED2, RC3H2, STK40, SLITRK1, SMO, SMPD3, SPTBN2, TNKS2, EP300, ANKRD11, WDTC1, SLITRK6, SP2, PDE4D, WDR48, APBA2, ZFP36L1, TAF10, PALB2, APBA1, EN1, ADD1, FKBP8, STIL, SLC12A5, TAL2, GIGYF2, KAT2A, CCM2, WWTR1, DHCR7, RARG, COMP, SLC25A25, KLF2, IHH, PKDCC, H3-3A, SLC4A10, RMI1, TP53, RARA, GPD2, PPP1R13L, UNC79 |
| multicellular organismal homeostasis | biological process | NDN, TNS2, PPP1R13L |
| multicellular organismal iron ion homeostasis | biological process | HFE, BMP6, SLC11A1, HYAL2, SLC40A1, HAMP, BTBD9, RHAG |
| multicellular organismal macromolecule metabolic process | biological process | AKR1C3 |
| multicellular organismal reproductive process | biological process | COMT, PTPN11, GHRHR, UMODL1 |
| multicellular organismal response to stress | biological process | PTEN, IDO1, LRP11, KIAA0319, MECP2, PPP3CA, ADCYAP1R1 |
| multicellular organismal water homeostasis | biological process | SCNN1G, SCNN1A, AQP1, AVP, BPIFA1, SCNN1B |
| multinuclear osteoclast differentiation | biological process | SBNO2, TNFRSF11A |
| multiple spine synapse organization, single dendrite | biological process | CX3CR1 |
| multivesicular body assembly | biological process | CHMP2A, RAB11A, TSG101, CHMP5, VPS28, VTA1, VPS4B, CHMP4A, VPS36, HGS, STAM, CHMP4B, IST1, CHMP1A, CHMP6, STAM2, VPS37C, SNF8, VPS37A, PDCD6IP, VPS37B, CHMP4C, MVB12A, VPS25, CHMP7, CHMP3, CHMP1B |
| multivesicular body organization | biological process | RAB27A |
| multivesicular body sorting pathway | biological process | CHMP5, RAB27A, VTA1, EXPH5, SYTL4, RAB27B, MITD1, RUBCN, SNF8, UVRAG, VPS25, CHMP3 |
| multivesicular body-lysosome fusion | biological process | CHMP3 |
| muscle atrophy | biological process | GATM |
| muscle attachment | biological process | DAG1 |
| muscle cell apoptotic process | biological process | DMPK |
| muscle cell cellular homeostasis | biological process | SOD1, IL6, HIF1A, GAA, PFKM, MTM1, DMD, LARGE2, BAG3, CAPN3, LARGE1, CFL2, LAMP2, TRIM32, CAV3, ALDOA, LOX, PLG, SRF, MSTN, SGCZ, CHRNA1 |
| muscle cell development | biological process | MEGF10, NFATC4, SGCZ |
| muscle cell differentiation | biological process | SEMA4C, HIRA, SMARCD3, RORA, FBXO40, IFRD1, SOX6, QKI, MYOCD, SPEG, SYNE1, BIN1, H3-3A |
| muscle cell fate commitment | biological process | MYOD1, MYOG, FGF10 |
| muscle cell fate determination | biological process | MEF2C, TBX2 |
| muscle cell fate specification | biological process | MYL2 |
| muscle cell proliferation | biological process | MEGF10 |
| muscle contraction | biological process | MYH7, GNAO1, GJA1, OXTR, TPM1, SLC6A8, CACNA1S, GAMT, EMD, SORBS1, NDUFS6, DES, MYOM2, MYL6, UTS2, CKMT2, PXN, CHRNE, MYL12B, CRYAB, TPM3, ITGB5, MYL12A, CLCN1, UTRN, TRDN, ANKRD2, FXYD1, RYR1, MYH11, TPM4, MYH1, MYOM3, MYL10, CHRNB1, ACTN2, CAV3, CALD1, MYBPC2, TTN, HSBP1, CHRND, CALM1, LTB4R, SORBS3, SLMAP, CERT1, TACR2, SLC8A1, MYBPC1, VCL, MYL5, ASPH, TMOD3, TBX20, P2RX6, GLRA1, SSPN, MYOF, MYL6B, DRD1, TNNI2, SNTB1, CACNA1H, KCNIP2, CHRNG, HRC, TMOD4, DYSF, TPM2, TNNT1, SCN4A, SNTA1, PABPN1, HCN4, TLN1, MYH6, KCNJ12, MYLK, LMOD2, TRIM72, MYH8, TMOD1, TNNT3, MYOM1, SGCA, LMOD1, MYH13, TNNI1, GJC1, MYH2, ACTA2 |
| muscle fiber development | biological process | DMD, NEB, SGCB, CHRNB1, FLNC, NRAP, CACNA2D2, LOX, AFG3L2, NEBL, WFIKKN2, MYOF, MYL2, WFIKKN1, DYSF, COMP, UCHL1 |
| muscle filament sliding | biological process | MYH7, VIM, TPM1, DES, TCAP, MYL6, DMD, TPM3, NEB, MYL4, TPM4, MYBPC3, ACTC1, ACTN2, MYBPC2, TTN, MYBPC1, MYL6B, TNNI2, MYL2, ACTN3, TPM2, TNNT1, MYL3, MYH3, MYH6, MYH8, TMOD1, TNNT3, TNNI1, MYH2 |
| muscle hypertrophy | biological process | IGF1 |
| muscle organ development | biological process | CHD2, IGF1, NRG1, MEF2A, EMD, MEGF10, PAX7, SRI, FXR1, PRR14, DMD, FRG1, COPRS, SGCE, CRYAB, XBP1, NEB, BVES, FLNB, UTRN, CTF1, KMT5B, ANKRD2, FHL1, CAPN3, SGCB, MSX1, ID3, MEF2C, ZFHX3, CENPF, CAV3, EID2B, ZNF609, USP2, MRTFB, SGCD, CSRP3, CD164, EGR3, TWIST1, BTBD1, MEF2D, SOX6, PAXBP1, ETV1, HBEGF, MAPK12, SMTN, ALX4, H1-5, ADGRB1, LBX1, POU6F1, MSTN, CACNA1H, MYOD1, MYOG, FOXO4, TEAD4, FKTN, ITGA7, SRPK3, LAMA5, VAMP5, COL6A3, TCF15, COL19A1, SPEG, JPH1, ITGB1BP2, NPHS1, MYH3, EVC, FOXK1, TRIM72, UNC45B, UNC45A, MYMK, MEF2B, SGCA, MRAS, ITGA11, RIPOR2, CXCL10, MKX |
| muscle organ morphogenesis | biological process | LIF, SERP1, ARID5B, GSC, TCF15, CNTF, SMTNL1 |
| muscle structure development | biological process | PDLIM1, CAPN3, PDLIM2, RNF165, PDLIM5, LDB3, PDLIM7, PDLIM4, PDLIM3 |
| muscle system process | biological process | TRIM72, SCO2 |
| muscle tissue development | biological process | CSRP3, CSRP1, POGLUT1, SRPK3 |
| muscle tissue morphogenesis | biological process | PAX7, ADARB1 |
| muscular septum morphogenesis | biological process | FZD2, VANGL2, HEY2, FZD1 |
| musculoskeletal movement | biological process | CHRND, GIGYF2, COMP, CHRNA1 |
| musculoskeletal movement, spinal reflex action | biological process | ASCL1, DRD3 |
| MyD88-dependent toll-like receptor signaling pathway | biological process | TLR4, TLR2, HSPD1, LY96, MAP3K7, IRAK1, RPS27A, MYD88, IRAK2, TAB1, REG3G, IRAK3, TIRAP, TLR1, TLR10, TAB2, TRAF6, UBC, UBA52, TAB3, BTK, TNIP1, TLR9, TLR7, UBB, TLR5, TLR6, MAP3K1, IRAK4, CD36 |
| MyD88-independent toll-like receptor signaling pathway | biological process | TLR4, UBE2D3, TNIP3, LY96, RPS27A, BIRC2, IKBKG, TICAM2, UBC, UBE2D1, UBA52, IKBKB, TLR3, UBB, TICAM1 |
| myelin assembly | biological process | PIKFYVE, PMP22, ILK, GPC1, TPPP |
| myelin maintenance | biological process | CXCR4, EPB41L3, ABCD2, DEGS1, ABCD1 |
| myelination | biological process | TGFB1, ERBB2, HEXB, NRG1, PMP22, FAM126A, MPZ, JAM3, GNPAT, TSC1, PSAP, MALL, MYO5A, GALC, NAB1, SLC8A3, MARVELD1, ZNF24, SBF2, SCN2A, ACER3, AFG3L2, MBP, ZNF165, MAL2, EGR2, NFASC, QKI, EIF2B2, SERINC5, DHH, TSPAN2, LPAR1, EIF2B5, ZNF215, MAL, KEL, TNFRSF21, NAB2, LGI4, AMIGO1, ACSBG1, KLK6, CMTM8, EIF2B4, SCN8A, PLLP |
| myelination in peripheral nervous system | biological process | ARHGEF10, SLC25A46, SKI, NTRK2, SIRT2, PARD3, ADAM22, POU3F2, SH3TC2, ILK, DAG1, LGI4, CNTNAP1, NF1, MYOC |
| myeloid cell apoptotic process | biological process | ARF6 |
| myeloid cell development | biological process | EVI2B, PABPC4 |
| myeloid cell differentiation | biological process | PIR, NCOA6, PRKX, CBFB, RUNX1, RASGRP4, TIRAP, SNRK, CEBPE, PRDX3, HOXB7, IFI16, PML, IRF8, CLEC5A, ZBTB16, TCIRG1, TET2, KAT6A, L3MBTL3, THPO, GATA1 |
| myeloid cell homeostasis | biological process | SOD1, IL6, BAX, BAK1, BCL2L11, ITPKB, FANCC, NCKAP1L |
| myeloid dendritic cell activation | biological process | STARD7, HMGB1, PYCARD |
| myeloid dendritic cell activation involved in immune response | biological process | PYCARD, SLAMF1, DOCK2 |
| myeloid dendritic cell chemotaxis | biological process | ARHGEF5, CCL19, CCR7 |
| myeloid dendritic cell cytokine production | biological process | CAMK4 |
| myeloid dendritic cell differentiation | biological process | TGFB1, IL4, CAMK4, SPI1, DHRS2, BATF, UBD, BATF2, PSEN1, RBPJ, BATF3, TRAF6, TGFBR2, RELB, LTBR, DCSTAMP |
| myeloid leukocyte activation | biological process | TYROBP |
| myeloid leukocyte differentiation | biological process | KIT, SPI1, PSEN1 |
| myeloid progenitor cell differentiation | biological process | KIT, MLF1, JAM3 |
| myo-inositol transport | biological process | PGAP1, SLC2A13, SLC5A1 |
| myoblast development | biological process | MEGF10, SOX15, SDC1 |
| myoblast differentiation | biological process | CTNNB1, IGF1, RB1, SHH, KCNAB1, HMGCR, MBNL1, PLEKHM3, DDX17, MAPK12, PLG, FGF6, MYOD1, MYOG, HINFP, DTYMK, JAG1, MAML1 |
| myoblast differentiation involved in skeletal muscle regeneration | biological process | MAPK14, WNT10B |
| myoblast fate commitment | biological process | TCF7L2, EPAS1 |
| myoblast fate determination | biological process | IFRD1, MYOD1 |
| myoblast fusion | biological process | GSK3B, CAPN2, DYRK1B, ERVW-1, CAV3, FER1L5, CDON, ADGRB3, ERVFRD-1, PLEKHO1, MYOF, CACNA1H, MYOD1, MYH9, JAM2, NPHS1, MYMK, ADAM12, TANC1 |
| myoblast fusion involved in skeletal muscle regeneration | biological process | CD81, PTGFRN, MYMK |
| myoblast migration | biological process | MEGF10, ROCK1, SMO, ITGB1BP1, PLEKHO1, SIX1, SIX4, THBS4, NET1 |
| myoblast migration involved in skeletal muscle regeneration | biological process | ANXA1, AKIRIN1, MSTN, BIN3 |
| myoblast proliferation | biological process | GPX1, IGF1, HGF |
| myofibril assembly | biological process | MYH10, CAPN3, KLHL41, PGM5, TMOD3, FLII, TMOD4, MYH6, LMOD2, TMOD1, LMOD1, MYOZ1 |
| myosin filament assembly | biological process | RAP1GDS1 |
| myotome development | biological process | WDR19, SIX1, SIX4 |
| myotube cell development | biological process | IGF1, NFATC2, MYOD1 |
| myotube differentiation | biological process | GSK3B, GPX1, SHH, SKI, MEF2C, CAV3, SORT1, MYEF2, BARX2, MYOD1, MYOG, PLD3 |
| myotube differentiation involved in skeletal muscle regeneration | biological process | BCL9, KLF5, MYOD1 |
| N-acetylglucosamine biosynthetic process | biological process | GNE, NANP |
| N-acetylglucosamine catabolic process | biological process | GNPDA1, GNPDA2, AMDHD2 |
| N-acetylglucosamine metabolic process | biological process | MGEA5, EXTL2, LARGE1, GNPDA1, NAGK, GNPDA2, CHST6, CHST4, GNPNAT1, RENBP, AMDHD2, CHST5, CHST2, MGAT3, CHST3, CHST7 |
| N-acetylmannosamine metabolic process | biological process | NAGK, RENBP |
| N-acetylneuraminate biosynthetic process | biological process | NANP |
| N-acetylneuraminate catabolic process | biological process | NPL, GNPDA1, NAGK, GNPDA2, RENBP, AMDHD2 |
| N-acetylneuraminate metabolic process | biological process | CMAS, ST6GAL1, GNE, ST3GAL1 |
| N-acylethanolamine metabolic process | biological process | GDPD3, NAPEPLD, GDE1, NAAA, GDPD1 |
| N-acylphosphatidylethanolamine metabolic process | biological process | PLAAT1, PLAAT3, PLAAT5, NAPEPLD, ABHD4 |
| N-glycan fucosylation | biological process | FUT6, FUT8 |
| N-glycan processing | biological process | MAN1B1, MAN2A1, MGAT4A, MAN2A2, MAN1A2, ST8SIA2, ST8SIA4, FUT8, PRKCSH, ST8SIA1, MAN1C1, MAN1A1, MGAT4B, ST8SIA5, ST8SIA3 |
| N-terminal peptidyl-alanine methylation | biological process | NTMT1 |
| N-terminal peptidyl-alanine trimethylation | biological process | NTMT1 |
| N-terminal peptidyl-aspartic acid acetylation | biological process | NAA80 |
| N-terminal peptidyl-glutamic acid acetylation | biological process | NAA80, NAA10 |
| N-terminal peptidyl-glycine methylation | biological process | NTMT1 |
| N-terminal peptidyl-glycine N-myristoylation | biological process | NMT1, NMT2 |
| N-terminal peptidyl-L-cysteine N-palmitoylation | biological process | MAP6D1 |
| N-terminal peptidyl-lysine acetylation | biological process | CREBBP, EP300, KAT2B |
| N-terminal peptidyl-methionine acetylation | biological process | NAA20, NAA25, NAA35, NAA16, NAA30, NAA15, NAA60 |
| N-terminal peptidyl-proline dimethylation | biological process | NTMT1 |
| N-terminal peptidyl-proline methylation | biological process | NTMT1 |
| N-terminal peptidyl-serine acetylation | biological process | NAA10 |
| N-terminal peptidyl-serine dimethylation | biological process | NTMT1 |
| N-terminal peptidyl-serine methylation | biological process | NTMT1 |
| N-terminal peptidyl-serine trimethylation | biological process | NTMT1 |
| N-terminal protein amino acid acetylation | biological process | NAA35, NAA16, NAA40, NAA50, NAA15, NAA10, AANAT, NAA60 |
| N-terminal protein amino acid methylation | biological process | NTMT1 |
| N-terminal protein amino acid modification | biological process | METAP2, METAP1D, PDF, METAP1 |
| N-terminal protein myristoylation | biological process | PPM1B, NMT1, PPM1A, NMT2 |
| NAD biosynthesis via nicotinamide riboside salvage pathway | biological process | SLC5A8, NAMPT, NAPRT, PARP16, NUDT12, PTGIS, NAXD, SLC22A13, RNLS, PARP10, NNMT |
| NAD biosynthetic process | biological process | HAAO, NMNAT1, NMRK1, KYNU, NADSYN1, NMNAT3, NAMPT, NAPRT, ASPDH, QPRT, NMNAT2, NMRK2, AFMID |
| NAD catabolic process | biological process | SARM1, NUDT17, NUDT12 |
| NAD metabolic process | biological process | LDHA, NMNAT1, NMRK1, CD38, NADK2, MDH1, NADK, NADSYN1, NMNAT3, NT5E, GPD1L, BST1, QPRT, NMNAT2, NMRK2 |
| NAD salvage | biological process | NAPRT |
| NAD transmembrane transport | biological process | SLC25A17 |
| NAD transport | biological process | P2RX7 |
| NAD-cap decapping | biological process | DXO, NUDT12 |
| NADH dehydrogenase complex assembly | biological process | NDUFAF1 |
| NADH metabolic process | biological process | MDH2, MDH1, NUDT17, NUDT12, GPD1L, MDH1B |
| NADH oxidation | biological process | ALDOB, GPD1L |
| NADP biosynthetic process | biological process | NADK2, NADK, IDH2 |
| NADP catabolic process | biological process | NUDT17, NUDT12 |
| NADP metabolic process | biological process | G6PD, DCXR, NOX1, TP53I3, IDH2, GCK |
| NADPH oxidation | biological process | PRDX5, KCNAB2, FMO1 |
| NADPH regeneration | biological process | IDH1, G6PD, NNT |
| nail development | biological process | ITGA6, PRKAB1, KRT84, FOXN1, ITGB4, HOXC13 |
| naphthalene metabolic process | biological process | AKR1B1 |
| natural killer cell activation | biological process | IL18, CASP8, IL2, NCR3, RASGRP1, NCR1, IL21R, CD2, ITGB2, ULBP3, ULBP2, PIK3CD, ULBP1, SLAMF7 |
| natural killer cell activation involved in immune response | biological process | IFNA1, IFNA8, IFNA10, CD244, IFNA2, IFNA14, IFNW1 |
| natural killer cell chemotaxis | biological process | PIK3CG, PIK3CD |
| natural killer cell degranulation | biological process | RAB27A, VAMP7, UNC13D, CORO1A |
| natural killer cell differentiation | biological process | AXL, STAT5B, RABL3, SP3, PTPRC, TUSC2, ID2, PIK3CD, MERTK, TYRO3 |
| natural killer cell inhibitory signaling pathway | biological process | KIR2DL1 |
| natural killer cell mediated cytotoxicity | biological process | PRDX1, CEBPG, LYST, GZMB, PTPN6, TUBB, TUBB4B, RAET1E, ULBP3, ULBP2, ULBP1, SLAMF7 |
| natural killer cell mediated immunity | biological process | KLRC2 |
| natural killer cell proliferation | biological process | ELF4 |
| natural killer cell tolerance induction | biological process | LGALS9, HAVCR2 |
| ncRNA deadenylation | biological process | PARN |
| ncRNA polyadenylation | biological process | TENT4B |
| ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process | biological process | TENT4B |
| ncRNA processing | biological process | ZCCHC8, NAT10 |
| necroptotic process | biological process | FASLG, TLR4, DNM1L, LY96, BIRC2, PPIF, CYLD, ITPK1, TICAM2, PYGL, RIPK3, PGAM5, TLR3, IPMK, TP53, TICAM1 |
| necroptotic signaling pathway | biological process | TNF, FAS, FASLG, FADD, RIPK3, TLR3 |
| necrotic cell death | biological process | GSDME |
| negative chemotaxis | biological process | SEMA7A, SEMA3A, ITGAV, FLRT3, SEMA3E, RYK, SEMA6D, LRTM1, SEMA3F, SEMA4C, SEMA3G, SEMA4G, SLIT1, SEMA4D, FLRT2, EFNA5, PDGFA, NRP2, APOA1, ITGB3, DPP4, SEMA6A, SEMA3B, EPHA7, SEMA3C, SEMA6C, SEMA6B, PLXNA3, LGR6, SEMA4B, SLIT3, SLIT2, LRTM2 |
| negative regulation by host of symbiont molecular function | biological process | RAB9A, SFTPD |
| negative regulation by host of viral exo-alpha-sialidase activity | biological process | APCS |
| negative regulation by host of viral genome replication | biological process | CCL8, ZC3H12A, VAPB, PRKN, VAPA, CCNK |
| negative regulation by host of viral glycoprotein metabolic process | biological process | APCS |
| negative regulation by host of viral process | biological process | LTF, APCS |
| negative regulation by host of viral release from host cell | biological process | VAPB |
| negative regulation by host of viral transcription | biological process | CCL5, CCL3, REST, HMGA2, INPP5K, ZNF639, TFAP4 |
| negative regulation by symbiont of host apoptotic process | biological process | SERPINB9 |
| negative regulation by virus of viral protein levels in host cell | biological process | STAT1, VAPB |
| negative regulation of 3'-UTR-mediated mRNA stabilization | biological process | METTL16 |
| negative regulation of actin cytoskeleton reorganization | biological process | TJP1 |
| negative regulation of actin filament binding | biological process | CRMP1 |
| negative regulation of actin filament bundle assembly | biological process | PRKN, SHANK1 |
| negative regulation of actin filament depolymerization | biological process | SWAP70, PLEKHH2, LIMA1 |
| negative regulation of actin filament polymerization | biological process | KANK1, TWF1, KANK4, ARFGEF1, PFN2, KANK3, MKKS, BBS4, SSH2, PRKCD, SSH3, MYADM, TWF2, SSH1, FHOD3, HIP1R, SLIT2 |
| negative regulation of actin filament severing | biological process | CSRP3, MYH9 |
| negative regulation of actin nucleation | biological process | CORO1A |
| negative regulation of action potential | biological process | SUMO1, CNR1, CHRNB2 |
| negative regulation of activated T cell proliferation | biological process | CASP3, PRNP, LGALS9, CD274, SCRIB, LRRC32, RC3H1, PDCD1LG2, CRTAM |
| negative regulation of activation of membrane attack complex | biological process | CD59 |
| negative regulation of activation-induced cell death of T cells | biological process | TSC22D3, FADD, GPAM |
| negative regulation of activin receptor signaling pathway | biological process | FST, CER1, ACVR1, FSTL3, SKI, LEMD3, MAGI2 |
| negative regulation of acute inflammatory response | biological process | IL4, GSTP1, PPARG, NLRP3, ASH1L, APCS, INS |
| negative regulation of acute inflammatory response to antigenic stimulus | biological process | SELENOS, FCGR2B, NPY5R |
| negative regulation of adaptive immune memory response | biological process | TNFRSF14, CD160 |
| negative regulation of adaptive immune response | biological process | SAMSN1 |
| negative regulation of adenosine receptor signaling pathway | biological process | ADA |
| negative regulation of adenylate cyclase activity | biological process | GRM3, GNAI2, GNAI3, NPR3, EDNRB, AKAP9, ADGRV1, GRM2, DRD3, PALM, GALR1, AKAP5, LTB4R2, DRD2, GALR3 |
| negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway | biological process | ARRDC3 |
| negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process | biological process | GNAI2 |
| negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | biological process | MRAP2, SSTR4, OPRL1, APLP1 |
| negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process | biological process | RGS2 |
| negative regulation of adherens junction organization | biological process | RDX, BMP6 |
| negative regulation of adiponectin secretion | biological process | IL1B, RAB11FIP5, RAB11FIP1, RAB11FIP3 |
| negative regulation of adipose tissue development | biological process | KLF7, POU4F2 |
| negative regulation of aldosterone biosynthetic process | biological process | REST, BMP5, BMP2 |
| negative regulation of alkaline phosphatase activity | biological process | TNF, SEMA4D, TGFB2 |
| negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity | biological process | SLC27A4 |
| negative regulation of alpha-beta T cell activation | biological process | ADORA2A |
| negative regulation of alpha-beta T cell differentiation | biological process | SHH, GLI3, IHH |
| negative regulation of alpha-beta T cell proliferation | biological process | TNFRSF14 |
| negative regulation of amacrine cell differentiation | biological process | POU4F2 |
| negative regulation of amniotic stem cell differentiation | biological process | REST |
| negative regulation of amyloid fibril formation | biological process | IAPP, CRYAB, LDLR, HSPG2 |
| negative regulation of amyloid precursor protein biosynthetic process | biological process | ITM2C, BACE2, AGO2, AATF, ITM2A, ABCA7 |
| negative regulation of amyloid precursor protein catabolic process | biological process | PRNP, ROCK1 |
| negative regulation of amyloid-beta clearance | biological process | IFNGR1, HMGCR, LRPAP1, MYOCD, CYP51A1, SRF, TNF |
| negative regulation of androgen biosynthetic process | biological process | WNT4 |
| negative regulation of androgen receptor signaling pathway | biological process | NODAL, SMARCA4, PIAS2, DAB2, FOXP1, NCOR2, NCOR1, ZBTB7A, FOXH1 |
| negative regulation of angiogenesis | biological process | DCN, LIF, STAT1, FASLG, GHRL, KLK3, SEMA3E, KLF4, PLK2, CCN6, SHC1, SPINK5, HOXA5, PTN, DAB2IP, CLDN5, TIE1, ROCK2, SPRED1, HGS, AMOT, FBLN5, THBS1, COL4A2, TEK, FOXJ2, CNMD, PF4, ROCK1, GADD45A, GPR4, ANGPT4, COL4A3, STAB1, ADGRB3, SARS1, MECP2, TGFB2, YJEFN3, PTPRM, KRIT1, PDE3B, ANGPT2, ALOX5, PML, CX3CR1, ATF2, HSPG2, SEMA6A, RGCC, ADGRB2, CXCR3, EMILIN1, SPRY2, NPR1, AGO1, ADGRB1, EPHA2, FOXO4, SULF1, IL17F, CD160, HRG, THBS4, FOXC1, SERPINF1, HHEX, VASH1, GDF2, THBS2, ISM1, AGT, NF1, EFNA3, GTF2I, NIBAN2, SYNJ2BP, APOH, CXCL10 |
| negative regulation of anion channel activity | biological process | TCAF2 |
| negative regulation of anoikis | biological process | BCL2, ITGB1, ITGA5, SRC, PIK3CA, MCL1, PDK4, TLE1, PTRH2, PTK2, NOTCH1, NTRK2, CEACAM6, BCL2L1, CAV1 |
| negative regulation of anterograde synaptic vesicle transport | biological process | CNIH2 |
| negative regulation of anti-Mullerian hormone signaling pathway | biological process | AMHR2 |
| negative regulation of antibacterial peptide production | biological process | SPINK5 |
| negative regulation of antibody-dependent cellular cytotoxicity | biological process | FCGR2B |
| negative regulation of antifungal innate immune response | biological process | FAM3A |
| negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I | biological process | HFE |
| negative regulation of antigen processing and presentation of peptide antigen via MHC class I | biological process | TAPBPL |
| negative regulation of antigen processing and presentation of peptide antigen via MHC class II | biological process | HLA-DOA |
| negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological process | THBS1 |
| negative regulation of apolipoprotein binding | biological process | MAPK3 |
| negative regulation of apoptotic cell clearance | biological process | HMGB1, CD300LF |
| negative regulation of apoptotic DNA fragmentation | biological process | NMNAT1, DFFA, PAM16 |
| negative regulation of apoptotic process | biological process | SOD1, EGFR, TIMP1, TP53, IL4, IL6, BCL2, MMP9, VEGFA, CD44, WT1, KITLG, IL10, FAS, IL6ST, SOX9, INSL3, SOX10, HIF1A, RXFP2, BCL2L2, BIRC5, OGG1, CDK1, MGMT, AXL, AKT1, HNF1B, KDR, CASP3, GSK3B, UBE2B, MDM2, GAS6, CIB1, ARNT2, GHRL, GNRH1, ALB, HSPB1, GPX1, GSTP1, CLU, PRLR, EDNRA, HSPA9, STAT3, LEP, BAG6, PTEN, PLAUR, PARK7, LTF, CAT, IGF1, IGF1R, HSPA5, BMP4, SRC, MIF, HGF, MAPK8, ARHGDIA, IL2, PDCD1, TEX11, INSL6, PROP1, NGF, FN1, RAF1, HSPD1, PRDX2, FGF8, ADAMTS20, MCL1, FOXO1, SHH, PROK2, AIF1, MAEL, SIN3A, TP63, MYC, ANXA5, ANXA4, GDNF, MALT1, CCN1, PRNP, GLI3, AKR1B1, ARF4, RASA1, RPS3A, COPS5, USP47, WNK3, DDX3X, PIAS1, TNFAIP8, NPM1, YBX3, PAX7, CD38, GRK5, GLO1, FXN, RB1CC1, ITCH, PAFAH2, PDCD10, PLK2, HIGD1A, EEF2K, SOCS2, DYRK3, CD74, PPT1, XIAP, DHRS2, ARL6IP1, RGN, ASIC2, SUPV3L1, AGO4, PRELID1, SIAH2, RARB, IL7, TDGF1, EPCAM, PIK3R1, SHC1, BCL6, CIAPIN1, HDAC2, TAF9B, ATAD3A, LHX3, MAPK8IP1, LAMTOR5, CRYAB, PROC, HSP90B1, XBP1, BCL3, RPS6KB1, LTK, CTNNA1, SNCA, IRAK1, STAT5B, ADAR, RPS27A, PPARD |
| negative regulation of apoptotic process in bone marrow cell | biological process | PLK2, LEF1, FLT3LG |
| negative regulation of apoptotic process involved in metanephric collecting duct development | biological process | PAX8 |
| negative regulation of apoptotic process involved in metanephric nephron tubule development | biological process | PAX8 |
| negative regulation of apoptotic process involved in outflow tract morphogenesis | biological process | FOXC2, FOXC1 |
| negative regulation of apoptotic signaling pathway | biological process | BCL2, BAX, HSPB1, CTNNB1, NANOS3, GNAI2, PCGF2, TMBIM6, GNAI3, MAZ, WNT4, ING2, NR4A2, PSEN1, MEIS3, CSNK2A1, CTH, CX3CR1, AATF, MNT, FAIM2, QARS1, MAPK8IP2, ASAH2, TNF |
| negative regulation of appetite | biological process | LEP, NUCB2, GHSR, UCN, NENF, NPFF, CARTPT, CCK, PPARA |
| negative regulation of appetite by leptin-mediated signaling pathway | biological process | LEP, BBS2, MKKS, BBS4 |
| negative regulation of arachidonic acid secretion | biological process | ATP5PF, PLA2R1 |
| negative regulation of Arp2/3 complex-mediated actin nucleation | biological process | PICK1, CORO1B, CTNNA2, GMFB, GMFG, HIP1R |
| negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | biological process | SORL1, BIN1 |
| negative regulation of aspartic-type peptidase activity | biological process | NLRP7 |
| negative regulation of astrocyte activation | biological process | LDLR, NR1D1 |
| negative regulation of astrocyte differentiation | biological process | MBD1, MYCN, GPR37L1, ID4, F2, NF1 |
| negative regulation of asymmetric cell division | biological process | ASPM |
| negative regulation of ATF6-mediated unfolded protein response | biological process | WFS1, ATF6B |
| negative regulation of ATP biosynthetic process | biological process | PID1, FLCN |
| negative regulation of ATP citrate synthase activity | biological process | PHPT1 |
| negative regulation of ATPase activity | biological process | LTF, CNN3, TSC1, ATP5IF1, PXK, PPIF, PLN, VCPKMT, OXA1L, PAM16 |
| negative regulation of ATPase-coupled calcium transmembrane transporter activity | biological process | THADA, PLN, C4orf3, TLR9 |
| negative regulation of autophagic cell death | biological process | TREM2 |
| negative regulation of autophagosome assembly | biological process | MTM1, SEC22B, FEZ2, SCFD1, CHMP4A, TMEM39A, NUPR1, PHF23, CHMP4B, FEZ1, PINK1, SMCR8, LRRK2 |
| negative regulation of autophagosome maturation | biological process | TMEM39A, PHF23, RUBCN, CLEC16A, UBQLN4 |
| negative regulation of autophagy | biological process | BCL2, AKT1, LEP, MTOR, LEPR, HGF, GATA4, DAP, EIF4G2, TLK2, KDM4A, PTK2, KLHL22, RRAGA, NUPR1, IL10RA, NAMPT, SIRT2, MTMR8, PTPN22, ADRA1A, EIF4E, MTMR9, TAB2, CPTP, FOXK2, RUBCN, TAB3, BMF, WDR6, TREM2, MT3, BCL2L1, FOXK1, GOLGA2, KIF25, HERC1, RASIP1, TBC1D14, HTR2B, ZKSCAN3 |
| negative regulation of autophagy of mitochondrion | biological process | PINK1 |
| negative regulation of axon extension | biological process | SEMA3A, SEMA6D, BCL11A, RTN4, RTN4R, CDKL3, SEMA3G, RNF6, NTN1, DRAXIN, KIAA0319, MAP2, CDK5R1, IFRD1, MT3, SEMA6C, ARHGAP4, CDK5, PTPRS, NRP1, MAG, TRIM46 |
| negative regulation of axon extension involved in axon guidance | biological process | SEMA7A, SEMA3A, SEMA3E, RYK, SEMA6D, SEMA3F, SEMA4C, SEMA3G, SEMA4G, WNT3A, SEMA4D, SEMA6A, SEMA3B, SEMA3C, SEMA6C, SEMA6B, NRP1, PLXNA3, WNT3, SEMA4B, SEMA5A |
| negative regulation of axon extension involved in regeneration | biological process | KIAA0319 |
| negative regulation of axon regeneration | biological process | RTN4R, INPP5F, RGMA, KREMEN1, KLK8, EPHA4, LRIG2, PTPRS, RTN4RL1 |
| negative regulation of axonogenesis | biological process | PTEN, ARHGDIA, TRAK2, RTN4, RTN4R, EPHB2, PTK2, MCF2, PSEN1, RUFY3, EFNB3, THY1, NGFR, MAG, LRP4, LINGO1, GDI1 |
| negative regulation of B cell activation | biological process | FAS, BANK1, FOXJ1, FCGR2B, TBC1D10C, SAMSN1, INPP5D |
| negative regulation of B cell apoptotic process | biological process | IL2, BCL6, FOXP1, SLC39A10, IRS2, NOC2L, AURKB |
| negative regulation of B cell differentiation | biological process | INHBA, INHA, HMGB3, ID2 |
| negative regulation of B cell proliferation | biological process | IL10, CASP3, ATM, CDKN2A, PAWR, MNDA, CTLA4, FCGR2B, TYROBP, RC3H1, LYN, BTK, TNFRSF21, PKN1, TNFRSF13B, INPP5D |
| negative regulation of B cell receptor signaling pathway | biological process | LPXN, FCGR2B, GPS2, CD22, PLCL2 |
| negative regulation of barbed-end actin filament capping | biological process | CRACD, CARMIL1, CARMIL2, WASHC2C |
| negative regulation of behavior | biological process | ESR2 |
| negative regulation of behavioral fear response | biological process | CCK |
| negative regulation of beta-amyloid formation | biological process | APOE, CLU, PRNP, PIN1, NTRK2, ROCK1, SPON1, GGA3, CHRNA7, SORL1, ABCA7, BIN1, HAP1 |
| negative regulation of beta-catenin-TCF complex assembly | biological process | DACT1 |
| negative regulation of bicellular tight junction assembly | biological process | TNF, ROCK2, ROCK1, IKBKB |
| negative regulation of bile acid biosynthetic process | biological process | FGF19, PROX1 |
| negative regulation of binding | biological process | P2RY1, CYP2D6 |
| negative regulation of binding of sperm to zona pellucida | biological process | OVGP1, ASTL, ZP3 |
| negative regulation of biomineral tissue development | biological process | SOX9, GAS6, ROCK2, NOTCH1, ROCK1, HEY2, HEY1 |
| negative regulation of biosynthetic process | biological process | GSTP1 |
| negative regulation of blood circulation | biological process | AGER |
| negative regulation of blood coagulation | biological process | APOE, SERPINE1, ANXA5, TFPI, PROC, THBD, CD34, TSPAN8, PROS1, ADTRP, VTN, EDN1, APOH |
| negative regulation of blood coagulation, common pathway | biological process | FGA |
| negative regulation of blood pressure | biological process | NOS3, NOS2, OXT, RNPEP, MKKS, ADIPOQ, SNX5, UCN, CNR1, SCPEP1, VEGFC, GCH1, ABAT, FFAR3, CALCA, DRD3, GJA5, GUCA2B, RNLS, PTAFR, DRD2, OPRL1, PPARA, BDKRB1 |
| negative regulation of blood vessel diameter | biological process | WDR35, HMGCR, INS, SMTNL1 |
| negative regulation of blood vessel endothelial cell differentiation | biological process | FOXJ2 |
| negative regulation of blood vessel endothelial cell migration | biological process | TGFB1, APOE, CSNK2B, THBS1, MEF2C, HMGB1, GADD45A, ANGPT4, MECP2, ANGPT2, RGCC, JUP, HRG, FGF2, ACVRL1, VASH1, GDF2, TNF |
| negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | PDCD10, THBS1, NGFR |
| negative regulation of blood vessel remodeling | biological process | BCR, ABR |
| negative regulation of blood-brain barrier permeability | biological process | SH3GL2 |
| negative regulation of BMP signaling pathway | biological process | SKIL, CER1, LEMD2, NOTCH1, HJV, FSTL3, SKI, DKK1, GREM2, SMAD6, LRP2, SOSTDC1, SPART, HIPK2, LEMD3, ABL1, CTDSPL2, TWSG1, TOB1, PPM1A, SORL1, TRIM33, SFRP2, CHRD, DAND5, SMURF2, GDF3, BMPER, DLX1, VWC2, HTRA1, TMPRSS6, NBL1, FZD1, VWC2L, HTRA3, RBPMS2, GREM1, CAV1 |
| negative regulation of bone development | biological process | RGN |
| negative regulation of bone mineralization | biological process | SOX9, HIF1A, ECM1, CCR1, BCOR, CCL3, FGF23, ENPP1, STATH, SRGN, LTBP3, TRPM4, PTK2B, AHSG, GREM1, GATA1 |
| negative regulation of bone mineralization involved in bone maturation | biological process | RFLNB, RFLNA, GREM1 |
| negative regulation of bone remodeling | biological process | GREM1 |
| negative regulation of bone resorption | biological process | IAPP, GPR137B, CD38, TNFRSF11B, CLDN18, UBASH3B, P2RX7, CALCA, CARTPT, CSK, INPP5D |
| negative regulation of bone trabecula formation | biological process | CHAD, GREM1 |
| negative regulation of brain-derived neurotrophic factor receptor signaling pathway | biological process | FSTL4 |
| negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway | biological process | BMP4 |
| negative regulation of branching involved in lung morphogenesis | biological process | TNF |
| negative regulation of branching involved in ureteric bud morphogenesis | biological process | BMP4, TACSTD2 |
| negative regulation of branching morphogenesis of a nerve | biological process | IL1B, BCL11A |
| negative regulation of brown fat cell differentiation | biological process | FLCN |
| negative regulation of C-C chemokine binding | biological process | CCL23 |
| negative regulation of calcidiol 1-monooxygenase activity | biological process | CYP27B1, GFI1 |
| negative regulation of calcineurin-NFAT signaling cascade | biological process | PRNP, HOMER2, TBC1D10C, DYRK2, FHL2, MAPK7, CHP1, RCAN1, ACTN3, HOMER3, MYOZ1, MYOZ2 |
| negative regulation of calcium ion binding | biological process | SLN, PLN, C4orf3 |
| negative regulation of calcium ion export across plasma membrane | biological process | YWHAE |
| negative regulation of calcium ion import | biological process | SEMG1, EPPIN, SPINK1, SLN, SLC30A1, PLN |
| negative regulation of calcium ion import into sarcoplasmic reticulum | biological process | MRLN, PLN |
| negative regulation of calcium ion transmembrane transport | biological process | ATP1A2, CBARP |
| negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | biological process | SESTD1, BIN1 |
| negative regulation of calcium ion transmembrane transporter activity | biological process | SLN, ADRA2A, YWHAE, PLN |
| negative regulation of calcium ion transport | biological process | ICAM1, NOS3, PTGS2, GNAO1, CAV3, ADRA2A, PLN, INPP5K, CD33, PACSIN3 |
| negative regulation of calcium ion transport into cytosol | biological process | BCL2, TMBIM6, CALCA, EPO |
| negative regulation of calcium ion-dependent exocytosis | biological process | GNAI2, TRIM9, NOTCH1, REST, ADRA2A, STXBP3, CBARP, RAP1B |
| negative regulation of calcium-dependent ATPase activity | biological process | RGN |
| negative regulation of calcium-independent cell-cell adhesion | biological process | BMP2 |
| negative regulation of calcium-mediated signaling | biological process | PLEK, SLA2, ITPR1, CD22 |
| negative regulation of calcium:sodium antiporter activity | biological process | ATP1A2 |
| negative regulation of cAMP biosynthetic process | biological process | EDNRA |
| negative regulation of cAMP-dependent protein kinase activity | biological process | PRKAR2A, PRKAG2, PKIG, PKIA, PKIB, PRKAR2B, PRKAR1B |
| negative regulation of cAMP-mediated signaling | biological process | UBE2B, CRTC3, MGRN1, RGS2, PDE3A, PDE3B, PDE11A, CDC34, PDE4D, LPAR1, APLNR, PDE10A, PDE2A, OPRL1 |
| negative regulation of canonical Wnt signaling pathway | biological process | APOE, SOX9, SOX10, GSK3B, SOX2, FOXO1, SHH, NPHP4, PSMA3, TCF7L2, MAPK14, GLI3, PSMB1, PSMB5, PSMC2, EMD, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, DDIT3, CSNK1A1, PSMB2, ISL1, PSMC6, TLE1, PPP2R3A, STK3, G3BP1, PSMB7, PSMD6, PSMD1, PFDN5, PSMD14, SIAH2, PSMD7, STK4, MAPK8IP1, IGFBP1, PSMB6, DAB2IP, DVL1, SLC9A3R1, PSMD10, PSMD8, PSMC5, RUVBL2, PRKN, CTNND1, EGR1, PSMB4, DAB2, PSME1, UBAC2, PSMB8, PSMD4, KLHL12, FRZB, FERMT1, PSMC3, NOTCH1, PSMA6, TMEM131L, MDK, DRAXIN, KREMEN1, DKK1, SDHAF2, AXIN1, LRP6, RAPGEF1, LATS2, ANKRD6, MLLT3, RBMS3, APC, TLE4, SOSTDC1, CYLD, PSMD12, IGFBP4, PSMB9, PSMC4, PSMD9, DVL2, PSMA4, PSMD2, SCYL2, TMEM64, CCDC88C, LATS1, HECW1, PTPRU, MAD2L2, PSMD5, PSMF1, INVS, PSMB3, TLE2, LMBR1L, NPHP3, DACT1, WNT11, GLI1, IGFBP2, PTPRO, AMER1, AMER2, SFRP2, LZTS2, DKK4, PSMD3, PSMC1, RBX1, DVL3, LIMD1, AXIN2, BMP2, MCC, TLE5, SFRP5, WWTR1, FZD6, SFRP4, FUZ, FOXO3, APC2, GPC3, NKX2-5, NKD2, CTHRC1, PRICKLE1, CHD8, LRP4, ROR2, MAPK8IP2, NOTUM, TLE3, ZNRF3, FZD1, SHISA6, WNT5B, DKK2, AMFR, IGFBP6, |
| negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological process | DKK1 |
| negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation | biological process | TNN |
| negative regulation of cardiac chamber formation | biological process | TBX2 |
| negative regulation of cardiac muscle cell apoptotic process | biological process | NRG1, JAK2, SIRT5, SIRT4, NUPR1, MDK, PAX8, CFLAR, MYOCD, HEY2, RGL2, ILK, SFRP2, PPP1R10, NKX2-5, PDPK1, AMBRA1, HAND2 |
| negative regulation of cardiac muscle cell differentiation | biological process | DKK1, FZD7, SOX6, FRS2, BMP2, DLL1 |
| negative regulation of cardiac muscle cell myoblast differentiation | biological process | PRICKLE1 |
| negative regulation of cardiac muscle cell proliferation | biological process | GJA1, KCNK2, MAPK11, JARID2, TBX5, SAV1, CXADR, MEIS1, VGLL4, TGFBR2, RBP4 |
| negative regulation of cardiac muscle contraction | biological process | SRI, ZC3H12A, PIK3CG, PDE5A |
| negative regulation of cardiac muscle hypertrophy | biological process | GSK3B, GATA5, SMAD4, NOTCH1, GLRX3, MLIP, JARID2, CAV3, RGS2, P2RX4 |
| negative regulation of cardiac muscle hypertrophy in response to stress | biological process | ERRFI1, MLIP, SMAD3 |
| negative regulation of cardiac muscle tissue development | biological process | FGF8, FGF3 |
| negative regulation of cardiac muscle tissue regeneration | biological process | CDKN1B, CDKN1A |
| negative regulation of cardiac myofibril assembly | biological process | SMAD4 |
| negative regulation of cardiac vascular smooth muscle cell differentiation | biological process | HEY2 |
| negative regulation of cargo loading into COPII-coated vesicle | biological process | INSIG1 |
| negative regulation of cartilage development | biological process | LEP, CTSK, RARB, FRZB, WNT11, RARG, WNT9A, RARA |
| negative regulation of catabolic process | biological process | ZDHHC7 |
| negative regulation of catalytic activity | biological process | TIMP1, CD46, LMTK2, ANXA2, OAZ3, ANXA5, ANXA4, PRNP, PPP1R12A, HNRNPR, TXNIP, IL7, FAF2, UGT1A8, ANXA3, SLN, NQO1, NOTCH1, ARPP19, ANXA9, SCG5, FRY, CCAR2, WDTC1, NOSIP, MRLN, RNH1, PLN, PKIA, CAND1, ANP32E, FNIP2, SERPINB3, OAZ1, PRPSAP1, OAZ2, DGKH, TESC, CABP1, CLN3, TMBIM1, PDE6G, PPP1R12B, RENBP, PPP1R12C, ACACB, UGT1A7, PRPSAP2, NES |
| negative regulation of cation channel activity | biological process | MMP9, FGF12, EPO |
| negative regulation of caveolin-mediated endocytosis | biological process | UNC119, PROM2 |
| negative regulation of CD4-positive, alpha-beta T cell activation | biological process | TWSG1 |
| negative regulation of CD4-positive, alpha-beta T cell costimulation | biological process | CD160 |
| negative regulation of CD4-positive, alpha-beta T cell differentiation | biological process | CBFB, RUNX1, HMGB1 |
| negative regulation of CD4-positive, alpha-beta T cell proliferation | biological process | LGALS9, CD274, TWSG1, LGALS9B, VSIR |
| negative regulation of CD40 signaling pathway | biological process | SLAMF1 |
| negative regulation of CD8-positive, alpha-beta T cell activation | biological process | HFE, CD274 |
| negative regulation of CD8-positive, alpha-beta T cell differentiation | biological process | SOCS1, ZBTB7B |
| negative regulation of CD8-positive, alpha-beta T cell proliferation | biological process | VSIR |
| negative regulation of cell activation | biological process | EMILIN1 |
| negative regulation of cell adhesion | biological process | ARHGDIA, RASA1, LPXN, PIK3R1, PLXNC1, SEMA4D, MDK, FBLN1, MUC21, ANGPT1, CD164, PLXNA1, PDE3B, ADAM22, ADAMDEC1, TNC, TGFBI, MIA3, CBLL1, DSCAM, ARHGDIB, PLXNA4, DUSP1, PODXL, ERBB3, SIPA1, ARHGDIG, CDH13, SPN, PLXNB3, HRG, ACVRL1, JAM2, CLDN7, PLXNA3, PLXNB2, PLXNB1, PLXNA2, PLXND1, SEMA5A, RIPOR2, DACT2 |
| negative regulation of cell adhesion involved in sprouting angiogenesis | biological process | SEMA6A |
| negative regulation of cell adhesion involved in substrate-bound cell migration | biological process | ATP5F1B, PTPRC, ITGB1BP1 |
| negative regulation of cell adhesion mediated by integrin | biological process | SERPINE1, MUC1, PTPN11, CYP1B1, JAM3, PDE3B, HRG, ACER2 |
| negative regulation of cell adhesion molecule production | biological process | NOTCH1, APOA1, NOTCH4 |
| negative regulation of cell aging | biological process | PTEN, MIF, FOXM1, FZR1, MARCHF5 |
| negative regulation of cell cycle | biological process | TGFB1, INHBA, PTGS2, CASP3, BMP7, RB1, BMP4, INHA, PLAAT3, TP53BP2, TSPYL2, HTRA2, CREB3, RNF167, NUPR1, CHMP1A, HPGD, GATA3, PDCD4, MEN1, ETS1, NUDT6, RPS6KA2, CDK6, CDKN1B, TAF6, THAP5, MAPK12, PPP1R13B, SIPA1, BMP2, CDK5, ZBTB17, ALOX15B, BRINP1, NR4A1, TP53I13 |
| negative regulation of cell cycle arrest | biological process | MDM2, MIF, CDK9, RASSF1, FZD9, PHOX2B, MDM4, ZNF268, CCND1, HMGN5, EVI2B, RPL23, CALR, TFAP4, FOXE3, FGF10, GPER1 |
| negative regulation of cell cycle G1/S phase transition | biological process | CDKN2D, MEN1, SUSD2 |
| negative regulation of cell cycle G2/M phase transition | biological process | MACROH2A1 |
| negative regulation of cell cycle process | biological process | GPER1 |
| negative regulation of cell death | biological process | ESR2, MGMT, NFE2L2, BMP7, STAT3, PARK7, BMP4, CCL5, HSPA1A, HSPA1B, SRSF6, PACRG, NPAS2, CCN1, TXNDC12, CCN2, ZFPM2, CHMP2A, JAK2, CCN6, SMAD4, VPS4B, NCK1, PRKD1, ADNP2, HTRA2, PRKN, BNIP3L, NTF4, CHMP4B, NOTCH1, AGR2, CRH, ATG5, UCN, PARP16, AGR3, SRGAP2, SOX11, CACYBP, TTPA, BNIP3, BECN1, TEAD2, DUS2, LRPAP1, NPC1, HSPG2, SOX4, PPP5C, WNT11, CCN3, LRP1, PDE8A, FGF2, ADCYAP1R1, IMPACT, DRD2, WNT9A, TMEM109, CCN4, RAD18, CCN5, VPS35, HTR2B, WNT16 |
| negative regulation of cell development | biological process | NODAL, FRZB |
| negative regulation of cell differentiation | biological process | TGFB1, MAPK1, NR0B1, NODAL, ITGB1, CTNNB1, SHH, GLI3, IAPP, SKIL, SINHCAF, BCL6, ANP32B, KRAS, HES1, SUZ12, WNT4, NOTCH1, GDF11, PRAME, HOPX, P2RY12, PRAMEF8, CDK6, TWIST1, RBPJ, NOTCH4, SIX2, NOTCH3, POU4F2, DLL1, RARG, JAG1, IHH, FGF10, RARA |
| negative regulation of cell division | biological process | MYC, TXNIP, INTU, RFPL1, BLM, PTCH1, SUSD2 |
| negative regulation of cell fate commitment | biological process | SOSTDC1, GLIS1, SPDEF |
| negative regulation of cell fate determination | biological process | HES1 |
| negative regulation of cell growth | biological process | TGFB1, TP53, INHBA, BCL2, WT1, ESR2, CDKN2A, ENO1, GDF9, BMPR2, GJA1, PPARG, NF2, PTPRJ, DDX3X, SMARCA2, CGRRF1, SPHK2, SH3BP4, OSGIN2, PPT1, PPP2CA, RBBP7, RTN4, ING1, ACVR1B, BCL6, SMARCA4, BTG1, BST2, SMAD4, ADIPOR1, PPP1R9B, CRYAB, RACK1, PPARD, DCBLD2, TSPYL2, FHL1, ST7L, FRZB, WFDC1, FBP1, APBB2, MSX1, ADIPOR2, CRLF3, ENPP1, CDKN2D, NAIF1, TRIM40, SCGB3A1, TP53TG5, EI24, TGFB2, CCAR2, GAS2L1, CYP27B1, CDA, CDKN1B, GNG4, TNK1, OSGIN1, CDKN2C, SERTAD2, PML, NME6, FLCN, TCHP, CDKN1A, HYAL2, WNT11, NPR1, MT3, HNF4A, CCN3, VGLL4, SIPA1, SFRP2, CDKN2AIP, SERTAD3, MYL2, PSRC1, MUL1, HRG, ACVRL1, SESN2, IP6K2, DNAJB2, CAPRIN2, ZC3H12D, APBB1, PPP2R1A, GDF2, DCSTAMP, PRDM11, SLIT3, SLIT2, AGT, SMAD3, BDKRB1, CCDC85B, EAF2, GREM1, HSPA1A, HSPA1B |
| negative regulation of cell growth involved in cardiac muscle cell development | biological process | PI16, CAV3, YY1, RGS2, PPARA, CTDP1, RGS4 |
| negative regulation of cell growth involved in contact inhibition | biological process | CDHR2 |
| negative regulation of cell migration | biological process | BCL2, SERPINE1, KANK1, PTEN, SHH, CYP1B1, TPM1, NF2, PTPRJ, RNF20, ARID2, GTPBP4, KLF4, ADARB1, CD74, RAP2B, SINHCAF, DUSP22, BST2, SRGAP3, TMIGD3, PTN, DPYSL3, DLG5, TP53INP1, CLDN5, SLC9A3R1, TIE1, DLC1, RNF41, RRAS, BCR, ABR, WNT4, ADIPOQ, CLIC4, SCAI, MITF, OSBPL8, PTPRT, ABHD2, SRGAP2, SRGAP2C, MCTP1, TBX5, IFITM1, STK26, ADORA3, VCL, CX3CR1, EPPK1, MIA3, PTPRU, DACH1, FLCN, CITED2, EPHA1, LIMCH1, TCAF1, WNT11, DUSP3, SFRP2, CHRD, SRF, NAV3, ABHD6, ZMYND8, NISCH, RAP2A, ARHGAP4, DAG1, MIIP, SULF1, PLXNB3, THY1, ENG, ACVRL1, IL24, FUZ, TMEFF2, ALOX15B, FOXO3, IGFBP5, PODN, MAPK15, DRD2, JAG1, SRGAP1, LDLRAD4, SLIT2, DPEP1, NF1, RECK, AFDN, MAGI2, ROBO1, NKX2-1, DUSP10 |
| negative regulation of cell migration involved in sprouting angiogenesis | biological process | KLF4, PDCD10, SPRED1, NOTCH1, THBS1, CARD10, STARD13, ITGB1BP1, MAP2K5, MEOX2, HDAC5, TBXA2R |
| negative regulation of cell motility | biological process | PIN1, AP1AR, CTNNA1, SLC9A3R1, SPINT2, GATA3, FBLN1, TACSTD2, WAS, CCDC125, CRK, FRMD5 |
| negative regulation of cell motility involved in cerebral cortex radial glia guided migration | biological process | BMERB1 |
| negative regulation of cell projection organization | biological process | ITGB1, SPRY2, ITGA3 |
| negative regulation of cell proliferation | biological process | TGFB1, IFNG, IL1B, TP53, IL6, INHBA, CXCL8, AR, BCL2, TGFB3, VDR, LIF, WT1, NOS3, ADM, PTGS2, SOX9, INSL3, BAX, BAK1, RXFP2, SOD2, HMOX1, CDKN2A, HSF1, CIB1, GNRH1, IL1A, ITGB1, BMP7, CTNNB1, STAT3, PTEN, CSNK2B, ADAMTS1, LDOC1, RB1, BMP4, KISS1R, RAF1, GJA1, CD9, F2R, PPARG, CYP1B1, ALDH1A2, NTRK1, AZGP1, NF2, DDR1, KISS1, SIRPG, TIMP2, S100A11, PTPRJ, GLI3, IAPP, HDAC4, CDKN3, AGBL4, ARID2, P3H3, OVOL2, GTPBP4, TRIM24, KLF4, JAK2, NPM1, SMARCA2, ADARB1, STK3, KARS1, TBRG1, LAS2, NDN, COPS8, CGRRF1, TSG101, SH3BP4, DDAH1, DHRS2, ZNF503, WDR77, ING1, SH2B3, SCIN, GSDME, CCN6, RARB, BCL6, BTG1, RBM10, STK4, AIMP2, SMAD4, BTG3, TNS2, PHOX2B, RAPGEF2, PDCD5, EEF1E1, PRKRA, CER1, TMIGD3, PMP22, PTH1R, DAB2IP, DLG5, KIFAP3, TP53INP1, NKX3-1, EIF2AK1, BTG4, SULT2B1, SLC9A3R1, NEURL1, NUP62, PPP2R5C, KANK2, DLC1, RNF41, FBXO2, SPRY1, FTH1, PTPN2, WARS1, GPNMB, DHCR24, TSC1, NFIB, PLPP1, HGS, MDM4, NUPR1, PTPN6, MXI1, ZNF268, CHERP, FRZB, ING2, PEMT, NCK2, FABP3, NOTCH1, CTBP2, REST, BNIPL, H2AC6, NACC2, CBFA2T3, GDF |
| negative regulation of cell proliferation involved in contact inhibition | biological process | SRPX, DACH1 |
| negative regulation of cell proliferation involved in heart morphogenesis | biological process | BMP4 |
| negative regulation of cell proliferation involved in heart valve morphogenesis | biological process | NOTCH1 |
| negative regulation of cell proliferation involved in kidney development | biological process | FLCN |
| negative regulation of cell proliferation involved in mesonephros development | biological process | GATA3 |
| negative regulation of cell size | biological process | AKT1, MTOR, PTEN, TSC1, CAV3, UCN, RDX, DEPTOR, AKT1S1 |
| negative regulation of cell volume | biological process | ANO6, CLCN3, P2RX7, KCNMA1 |
| negative regulation of cell-cell adhesion | biological process | TGFB1, CDH1, NF2, GTPBP4, JAK2, PTK2, SPINT2, MUC21, EPB41L5, ABL1, LEF1, PODXL, JAG1, B4GALNT2 |
| negative regulation of cell-cell adhesion mediated by cadherin | biological process | EPCAM, NOTCH1, MAD2L2, RGCC, BMP6, NOTCH4, PLG |
| negative regulation of cell-cell adhesion mediated by integrin | biological process | SWAP70, WNK1 |
| negative regulation of cell-matrix adhesion | biological process | CDKN2A, NF2, SEMA3E, RASA1, PIK3R1, BCL6, MAP4K4, THBS1, POSTN, HOXA7, CASK, JAG1, AJAP1, NF1, ACER2, MYOC |
| negative regulation of cell-substrate adhesion | biological process | FZD4, NOTCH1, GCNT2, MEN1, FZD7, ANGPT2, SPOCK1, LRP1, PTPRO, TBCD, PLG, DMTN, CORO2B |
| negative regulation of cellular biosynthetic process | biological process | TNF |
| negative regulation of cellular component movement | biological process | TGFBR3, SP100, ACTN1, CDKN1B, PKHD1, ACTN4 |
| negative regulation of cellular extravasation | biological process | BCR, ABR, IL27RA |
| negative regulation of cellular glucuronidation | biological process | UGT1A8, UGT1A4, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| negative regulation of cellular organofluorine metabolic process | biological process | CYP2D6 |
| negative regulation of cellular pH reduction | biological process | BCL2 |
| negative regulation of cellular protein catabolic process | biological process | NELL1, DAB2IP, ATRAID, CDK5RAP3, RIC1, RGP1 |
| negative regulation of cellular protein localization | biological process | VPS35 |
| negative regulation of cellular protein metabolic process | biological process | MIF, EDNRB, EDN1 |
| negative regulation of cellular respiration | biological process | FLCN, TRAP1 |
| negative regulation of cellular response to growth factor stimulus | biological process | CASK, SLIT2 |
| negative regulation of cellular response to heat | biological process | CD34 |
| negative regulation of cellular response to hepatocyte growth factor stimulus | biological process | ADAMTS12 |
| negative regulation of cellular response to hypoxia | biological process | DDAH1, CD34 |
| negative regulation of cellular response to insulin stimulus | biological process | LPL, APPL2 |
| negative regulation of cellular response to oxidative stress | biological process | OXR1, NCOA7 |
| negative regulation of cellular response to transforming growth factor beta stimulus | biological process | CFLAR, DLX1 |
| negative regulation of cellular response to vascular endothelial growth factor stimulus | biological process | ADAMTS12 |
| negative regulation of cellular senescence | biological process | TERT, TP63, RBL1, BCL2L12, PLK2, BCL6, YBX1, NAMPT, SLC30A10, HMGA2, MAP3K3, CDK6, PRKDC, TWIST1, ABL1, ZKSCAN3 |
| negative regulation of centriole elongation | biological process | CHMP2A, CCP110 |
| negative regulation of centriole replication | biological process | BRCA1, TRIM37, CDK5RAP2, RBM14, MDM1, KAT2A, KAT2B |
| negative regulation of centriole-centriole cohesion | biological process | NEK2 |
| negative regulation of centrosome duplication | biological process | NPM1, NUBP1, TMEM67, CCNF |
| negative regulation of ceramide biosynthetic process | biological process | ORMDL3, ORMDL2 |
| negative regulation of cerebellar granule cell precursor proliferation | biological process | SLC6A4 |
| negative regulation of cGMP-mediated signaling | biological process | THBS1, PDZD3, PDE11A, PDE10A, PDE2A |
| negative regulation of chaperone-mediated autophagy | biological process | SNRNP70, SNCA, CTSA |
| negative regulation of chaperone-mediated protein folding | biological process | PDCD5 |
| negative regulation of chemokine (C-C motif) ligand 5 production | biological process | IL10, TICAM2, MUL1 |
| negative regulation of chemokine (C-X-C motif) ligand 2 production | biological process | KLF4, MAP2K5 |
| negative regulation of chemokine biosynthetic process | biological process | IL6, ELANE, SIGIRR |
| negative regulation of chemokine production | biological process | LGALS9, EPHA2 |
| negative regulation of chemokine-mediated signaling pathway | biological process | CCL5, SH2B3, PADI2, SLIT3, SLIT2, ROBO1 |
| negative regulation of chemotaxis | biological process | ELANE, PTPN2, DUSP3 |
| negative regulation of cholangiocyte apoptotic process | biological process | MTOR, IGF1 |
| negative regulation of cholesterol biosynthetic process | biological process | SOD1, APOE, ERLIN1, SCAP, ERLIN2 |
| negative regulation of cholesterol efflux | biological process | EGF, APOE, SHH, PLA2G10, SREBF2, ABCA2 |
| negative regulation of cholesterol esterification | biological process | ABCA2 |
| negative regulation of cholesterol import | biological process | APOC3 |
| negative regulation of cholesterol storage | biological process | PPARG, NR1H3, CES1, PPARD, ABCG1, TTC39B, PPARA, NR1H2 |
| negative regulation of cholesterol transport | biological process | APOC1 |
| negative regulation of chondrocyte development | biological process | RFLNB, PTHLH, RFLNA |
| negative regulation of chondrocyte differentiation | biological process | SOX9, CTNNB1, BMP4, RARB, NKX3-2, TGFBR1, PTHLH, LTBP3, RARG, ADAMTS7, GLI2, CHADL, WNT9A, CCN4, ADAMTS12, GREM1, GDF5, EFEMP1 |
| negative regulation of chondrocyte proliferation | biological process | BMPR2, CCN3 |
| negative regulation of chorionic trophoblast cell proliferation | biological process | NODAL, ACVR1C |
| negative regulation of chromatin binding | biological process | SENP2, WAPL, TDG, MEPCE, BTAF1, PPP3CA, FBH1, NFATC4 |
| negative regulation of chromatin silencing | biological process | H1-4, ATAD2, H1-2, H1-8, H1-0, H1-5, H1-1, H1-3, ATAD2B |
| negative regulation of chromosome condensation | biological process | H3-3A |
| negative regulation of chronic inflammatory response | biological process | IL4, CYP19A1 |
| negative regulation of chronic inflammatory response to antigenic stimulus | biological process | IL10 |
| negative regulation of cilium assembly | biological process | CCP110, TBC1D30, CEP97, TCHP, EVI5L, TBC1D7 |
| negative regulation of circadian rhythm | biological process | SIN3A, SFPQ, PER2, CRY1, SUV39H2, CIPC, CRY2 |
| negative regulation of circadian sleep/wake cycle, non-REM sleep | biological process | ADA |
| negative regulation of circadian sleep/wake cycle, REM sleep | biological process | GHRL, CRH |
| negative regulation of circadian sleep/wake cycle, sleep | biological process | DRD2 |
| negative regulation of clathrin-dependent endocytosis | biological process | SH3GL3, UNC119 |
| negative regulation of coagulation | biological process | ANXA5, PROC, PROCR |
| negative regulation of cold-induced thermogenesis | biological process | CIDEA, DDIT3, IL15, NOVA2, LGR4, ADIPOQ, NOTCH1, ACVR2B, PLCL1, LAMA4, ACOT13, PCTP, ATF4, NPR3, RHEB, DOCK7, HOXC10, NRDC, TFE3, RBPJ, ARRDC3, FOXC2, FLCN, LNPEP, NR1D1, MAP2K6, ALDH1A1, ABHD6, ARNTL, WNT10B, ACTN3, ZNF423, ACOT11, PGAM5, TLE3, PLCL2, NOVA1, NR1H2 |
| negative regulation of collagen binding | biological process | GTPBP4 |
| negative regulation of collagen biosynthetic process | biological process | IL6, IL6R, PPARG, RAP1A, ERRFI1, PPARD, GOT1, EMILIN1, CIITA, NPPC, CYGB |
| negative regulation of collagen fibril organization | biological process | EMILIN1, CHADL |
| negative regulation of collateral sprouting | biological process | BCL11A, FSTL4, ULK2, DCC, IFRD1, EPHA7, PTPRS |
| negative regulation of collateral sprouting in absence of injury | biological process | SPART |
| negative regulation of collateral sprouting of intact axon in response to injury | biological process | SPP1 |
| negative regulation of complement activation | biological process | CD46, CD55, MASP1, SERPING1 |
| negative regulation of complement activation, alternative pathway | biological process | SUSD4, VSIG4 |
| negative regulation of complement activation, classical pathway | biological process | C4BPB, SUSD4 |
| negative regulation of complement activation, lectin pathway | biological process | A2M, SERPING1 |
| negative regulation of complement-dependent cytotoxicity | biological process | IL4, IL13 |
| negative regulation of connective tissue growth factor production | biological process | SLC2A10 |
| negative regulation of connective tissue replacement involved in inflammatory response wound healing | biological process | AGER |
| negative regulation of constitutive secretory pathway | biological process | RAB33B |
| negative regulation of convergent extension involved in axis elongation | biological process | NKD1 |
| negative regulation of core promoter binding | biological process | PSEN1, ID2 |
| negative regulation of corticotropin secretion | biological process | CRHBP |
| negative regulation of corticotropin-releasing hormone receptor activity | biological process | CRHBP |
| negative regulation of cortisol biosynthetic process | biological process | REST, BMP5, BMP2 |
| negative regulation of cortisol secretion | biological process | PTPN11 |
| negative regulation of CREB transcription factor activity | biological process | DDIT3, MSX2, ADGRG3, SIK1 |
| negative regulation of cyclic-nucleotide phosphodiesterase activity | biological process | RGN, AIP, MAPK7, EGLN1, SLC39A14 |
| negative regulation of cyclin-dependent protein kinase activity | biological process | CDKN1B, CDKN1A, CDKN1C |
| negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | CASP3, CDKN2A, NR2F2, CDK5RAP1, IPO5, CDKN2B, CDKN2D, MEN1, LATS2, PLK1, APC, HEXIM2, CDKN1B, CDKN2C, IPO7, LATS1, MYOCD, CDKN1A, INCA1, CDKN1C, FBXO7, HHEX, KAT2B, HEXIM1, TFAP4 |
| negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | PTEN |
| negative regulation of cystathionine beta-synthase activity | biological process | MTRR |
| negative regulation of cysteine-type endopeptidase activity | biological process | PCID2, IFI16, MT3 |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | IL6, VEGFA, RAG1, CD44, BIRC5, AKT1, MDM2, GAS6, GPX1, SRC, HGF, NGF, RAF1, BEX3, USP47, DDX3X, KLF4, TNFAIP8, XIAP, ARL6IP1, SIAH2, LAMTOR5, CRYAB, SNCA, LAMP3, DHCR24, POR, SERPINB9, BIRC7, IFI6, SH3RF1, THBS1, NAIP, HERPUD1, CDKN2D, CFLAR, BIRC2, TRIAP1, PRDX3, YWHAE, CSNK2A1, SFN, PRDX5, IGBP1, FNIP1, RPS6KA1, CARD16, LEF1, MT3, AQP1, SFRP2, TNFSF14, AVP, MAP2K5, MAGEA3, NGFR, MICAL1, ARRB2, WNT9A, ADORA2A, DPEP1, VIL1, TNF |
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological process | MMP9, PLAUR, PARK7, CAAP1, NLE1 |
| negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | biological process | RNF34 |
| negative regulation of cytokine activity | biological process | IL10 |
| negative regulation of cytokine biosynthetic process | biological process | TIA1, RNF128, ASB1 |
| negative regulation of cytokine production | biological process | IL10, NDRG2, NPTN, GPNMB, CRYBA1, TWSG1, SLC11A1, BTK, RPS6KA5, EPHA2, CLEC4A, ATP2B1, RPS6KA4, MERTK |
| negative regulation of cytokine production involved in inflammatory response | biological process | MEFV, ZC3H12A, PDCD4, ABCD2, NLRP7, APOD, MACIR, ADCY7, APPL2, CHID1, PYCARD, F2, ABCD1 |
| negative regulation of cytokine secretion | biological process | IL6, CX3CL1, CIDEA, LGR4, HDAC9, FCGR2B, TNFRSF4, SRGN, LRRC32, PTGER4, RGCC, NLRP12, PPP1R11 |
| negative regulation of cytokine secretion involved in immune response | biological process | TNF, IL10, ANGPT1, APOA1 |
| negative regulation of cytokine-mediated signaling pathway | biological process | IL1RN, ECM1, IRAK3, PTPRC, IL36RN, PXDN, PALM3, SIGIRR, CAV1 |
| negative regulation of cytokinesis | biological process | E2F7, E2F8, CHMP4C, AURKB |
| negative regulation of cytolysis | biological process | BAD |
| negative regulation of cytolysis by symbiont of host cells | biological process | KRT6A |
| negative regulation of cytoplasmic mRNA processing body assembly | biological process | NBDY |
| negative regulation of cytoplasmic translation | biological process | FMR1, UNK, CPEB4, CPEB1, CPEB2, CPEB3, RBM24 |
| negative regulation of cytoplasmic translational elongation | biological process | CPEB2, CPEB3 |
| negative regulation of cytoskeleton organization | biological process | ESPN, IQCJ-SCHIP1 |
| negative regulation of cytosolic calcium ion concentration | biological process | GOT1, ATP1A2, SLC8A1, DRD3, LRP1, ATP2B1, KCNK3, DRD2, GTF2I, SMAD3 |
| negative regulation of cytotoxic T cell degranulation | biological process | FCGR2B, CEACAM1 |
| negative regulation of death-inducing signaling complex assembly | biological process | PARK7 |
| negative regulation of defense response to bacterium | biological process | HAVCR2, SIRT2, MAPKBP1 |
| negative regulation of defense response to virus | biological process | IL2RA, C1QBP, ITCH, RNF26, PPM1B, TRAF3IP1, ILRUN, FGL2, TRIM38, PCBP2, HTRA1 |
| negative regulation of defense response to virus by host | biological process | TARBP2, MICB, MUL1 |
| negative regulation of delayed rectifier potassium channel activity | biological process | SUMO1, KCNAB1, ANK3, KCNE4, KCNE1, KCNE3 |
| negative regulation of dendrite development | biological process | GSK3B, BCL11A, CARM1, KIAA0319, DCC, ARF6, ZNF296 |
| negative regulation of dendrite extension | biological process | BCL11A, OSTN |
| negative regulation of dendrite morphogenesis | biological process | GSK3B, YWHAH, RAPGEF2, GORASP1, PPP3CA, NFATC4, TRPC5, TLX2 |
| negative regulation of dendritic cell antigen processing and presentation | biological process | FCGR2B, THBS1, FGL2 |
| negative regulation of dendritic cell apoptotic process | biological process | AXL, GAS6, CCL19, CCR7, CXCL12, CCL21 |
| negative regulation of dendritic cell chemotaxis | biological process | SLAMF8 |
| negative regulation of dendritic cell cytokine production | biological process | JAK3 |
| negative regulation of dendritic cell dendrite assembly | biological process | CCL21 |
| negative regulation of dendritic cell differentiation | biological process | HLA-G, FCGR2B, ZBTB46, TMEM176A |
| negative regulation of dendritic spine development | biological process | APOE, PLK2, HDAC2, FSTL4, SRGAP2C, PTPRS, ASAP1 |
| negative regulation of dendritic spine maintenance | biological process | APOE, PRNP, GRIN2B |
| negative regulation of dendritic spine morphogenesis | biological process | PTEN, UBE3A, EFNA1, DNM3, NGEF |
| negative regulation of dense core granule biogenesis | biological process | REST |
| negative regulation of deoxyribonuclease activity | biological process | DFFA |
| negative regulation of dephosphorylation | biological process | IQGAP1, INPP5K |
| negative regulation of dermatome development | biological process | SFRP2 |
| negative regulation of detection of glucose | biological process | FOXA2 |
| negative regulation of detection of mechanical stimulus involved in sensory perception of touch | biological process | CACNB3 |
| negative regulation of determination of dorsal identity | biological process | DDIT3, SOSTDC1 |
| negative regulation of developmental growth | biological process | FGFR3 |
| negative regulation of DNA binding | biological process | HMOX1, E2F1, SUMO1, JAK2, DDIT3, SUMO3, HDAC2, RSF1, CTNNBIP1, NFIB, MSX1, HMGA2, ILRUN, NFKBIA, SMO, SP100, CPNE1, IFI16, ZFP90, HABP4, ZNF462, LEF1, GZMA, ID2, WFIKKN2, WFIKKN1, MDFI, TFAP4, NEK2, HAND2 |
| negative regulation of DNA biosynthetic process | biological process | BMPR2, GJA1, RGN, KCNK2, ADIPOQ, DNAJC2, DACH1, DUSP1, CDKN1A, NPPC, ACVRL1, GDF2, NIBAN2, ANKRD1 |
| negative regulation of DNA catabolic process | biological process | RGN |
| negative regulation of DNA damage checkpoint | biological process | BRD4, DDX39B, THOC1, THOC5 |
| negative regulation of DNA damage response, signal transduction by p53 class mediator | biological process | CD44, MDM2, MIF, DYRK1A, DYRK3, CD74, PTTG1IP, MARCHF7, PSMD10, TWIST1, YJU2 |
| negative regulation of DNA demethylation | biological process | GATA3 |
| negative regulation of DNA helicase activity | biological process | MNAT1, MCM2 |
| negative regulation of DNA ligase activity | biological process | TFIP11 |
| negative regulation of DNA metabolic process | biological process | SUB1, GPER1 |
| negative regulation of DNA methylation | biological process | KMT2A |
| negative regulation of DNA methylation-dependent heterochromatin assembly | biological process | TET1, APOBEC1 |
| negative regulation of DNA recombination | biological process | MSH2, H1-4, H1-2, MSH6, RTEL1, H1-8, ZRANB3, H1-0, BLM, H1-5, H1-1, H1-3 |
| negative regulation of DNA recombination at telomere | biological process | TERF2IP |
| negative regulation of DNA repair | biological process | RPS3 |
| negative regulation of DNA replication | biological process | TGFB1, TGFB3, ATR, NF2, S100A11, GTPBP4, WAPL, TSPYL2, TTF1, SLFN11, RAD17, CDC6, HUS1, PDS5A, HCRT, ENPP7, GDF2, TP53 |
| negative regulation of DNA-templated transcription, elongation | biological process | SUPT4H1, SUPT5H |
| negative regulation of DNA-templated transcription, initiation | biological process | MORC1, THRA |
| negative regulation of dopamine metabolic process | biological process | COMT, ITGAM, ITGB2 |
| negative regulation of dopamine receptor signaling pathway | biological process | DRD3, PALM, DRD2, RGS4 |
| negative regulation of dopamine secretion | biological process | CNR1, ABAT, DRD2 |
| negative regulation of dopamine uptake involved in synaptic transmission | biological process | SNCA |
| negative regulation of dopaminergic neuron differentiation | biological process | GSK3B, SHH, WNT3A |
| negative regulation of double-strand break repair | biological process | UBR5, TRIP12, TWIST1, RNF169 |
| negative regulation of double-strand break repair via homologous recombination | biological process | POLQ, PARPBP, RECQL5, SHLD2, SMCHD1, SHLD1, FBH1, MAD2L2, TP53BP1, RIF1, MAGEF1, CGAS, HELB, UBQLN4 |
| negative regulation of double-strand break repair via nonhomologous end joining | biological process | ERCC6, HMGA2, CYREN, AUNIP, TFIP11 |
| negative regulation of double-strand break repair via single-strand annealing | biological process | OGG1 |
| negative regulation of double-stranded telomeric DNA binding | biological process | ERCC4 |
| negative regulation of early endosome to late endosome transport | biological process | SNX3, SNX12 |
| negative regulation of eating behavior | biological process | NMU, NAPEPLD, TTC21B, CCK |
| negative regulation of ectodermal cell fate specification | biological process | FZD7 |
| negative regulation of elastin biosynthetic process | biological process | HBEGF |
| negative regulation of electron transfer activity | biological process | ETFBKMT |
| negative regulation of endocytic recycling | biological process | ARHGAP1 |
| negative regulation of endocytosis | biological process | PRKD1, SNX33, PACSIN2, MCTP1, RUBCN, EPHA3, ABCA7, PACSIN3, LRSAM1, PACSIN1 |
| negative regulation of endodeoxyribonuclease activity | biological process | GZMA |
| negative regulation of endodermal cell differentiation | biological process | COL5A2, COL5A1 |
| negative regulation of endodermal cell fate specification | biological process | MESP1 |
| negative regulation of endopeptidase activity | biological process | SERPINC1, TIMP1, ANOS1, SERPINE1, AKT1, TFPI2, SERPINA1, C3, APP, A2M, SERPINA5, EPPIN, LCN1, SERPINA3, SLPI, TIMP2, PRNP, USP14, WFDC9, SERPINB7, TFPI, BST2, WFDC10A, ITIH2, SERPINB6, WFDC8, CSTB, CST2, PEBP1, SPINT2, TIMP3, C5, SERPINB2, SERPINB9, COL7A1, WFDC13, SPOCK2, CST11, WFDC1, SPINT1, PROS1, CST5, APLP2, SERPINF2, SERPINB1, RARRES1, UBE2Z, SMR3B, ROCK1, NLRP7, SERPINA7, SERPINA4, COL4A3, CSTA, SERPINB3, SPINT3, SERPINB5, BIRC6, PI3, SPOCK1, PSMF1, VTN, WFIKKN2, SERPINI1, WFDC2, TIMP4, SERPINB8, CST6, CRB2, ITIH6, CD109, WFIKKN1, UCHL5, HRG, SERPING1, RENBP, LXN, SERPINA10, CST4, FURIN, COL6A3, SERPINF1, ITIH4, WFDC3, WFDC12, AMBP, ITIH5, SERPINA9, SERPINA12, UBE2O, A2ML1, AGT, COL28A1, WFDC5, HMSD, PAPLN, RECK, AHSG, SERPINH1, ITIH3, SPP2, FETUB |
| negative regulation of endoplasmic reticulum calcium ion concentration | biological process | BAX, BAK1, THADA, RAP1GDS1, BCAP31, FIS1, TGM2, ATP2A1 |
| negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation | biological process | NCK1, NCK2, DNAJC3 |
| negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | PARK7, HSPA1A, WFS1, TXNDC12, SELENOS, XBP1, TMBIM6, CREB3, PRKN, OPA1, HERPUD1, PDX1, PTPN1, SYVN1, BCL2L1, MAGEA3, LRRK2 |
| negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway | biological process | PRKN, HYOU1 |
| negative regulation of endoplasmic reticulum unfolded protein response | biological process | CREBRF, XBP1, RACK1 |
| negative regulation of endoribonuclease activity | biological process | TMBIM6 |
| negative regulation of endothelial cell apoptotic process | biological process | IL4, ICAM1, IL11, IL10, SERPINE1, KDR, GAS6, NFE2L2, RAMP2, FGG, IL13, GATA3, TEK, FGB, ANGPT1, KRIT1, ABL1, MAPK7, GATA2, SCG2, ANGPTL4, PAK4, CDH5, TNIP2, FGA, FGF21, PDPK1, SEMA5A, NDNF |
| negative regulation of endothelial cell chemotaxis | biological process | NOTCH1, THBS1, HRG |
| negative regulation of endothelial cell differentiation | biological process | XDH, ZEB1, NOTCH4, ACVRL1, JAG1 |
| negative regulation of endothelial cell migration | biological process | DCN, NR2F2, DNAJA4, DAB2IP, ADAMTS9, THBS1, SP100, PTPRM, KRIT1, SVBP, ADGRB1, ACVRL1, SERPINF1, VASH1, GDF2, SLIT2, SYNJ2BP, APOH |
| negative regulation of endothelial cell proliferation | biological process | APOE, STAT1, GHRL, XDH, GJA1, NR2F2, THBS1, CNMD, ATP5IF1, CAV2, PTPRM, KRIT1, ALOX5, TGFBR1, AIMP1, RGCC, SCG2, CXCR3, SULF1, ENG, ACVRL1, VASH1, GDF2, NF1, SYNJ2BP, TNF, APOH, CAV1 |
| negative regulation of energy homeostasis | biological process | GHRL |
| negative regulation of entry of bacterium into host cell | biological process | ITGAV, KRT6A |
| negative regulation of eosinophil extravasation | biological process | PTGER4 |
| negative regulation of epidermal cell differentiation | biological process | EZH2, GDF3, DLL1 |
| negative regulation of epidermal growth factor receptor signaling pathway | biological process | EGFR, EGF, CDC42, PTPRJ, AREG, TSG101, ARHGEF7, ERRFI1, TGFA, DAB2IP, SH3GL2, NUP62, SPRY1, PTPN2, HGS, EPS15, STAM, EREG, STAM2, GRB2, CBL, RNF126, HBEGF, EPN1, SPRY2, DUSP3, BTC, CBLC, MVP, ZFYVE28, EPS15L1, PTPN3, SH3KBP1, RNF115 |
| negative regulation of epidermal growth factor-activated receptor activity | biological process | TSG101, SNX6, ERRFI1, SOCS5, SOCS4, CHMP6, PSEN1, CBL, GPRC5A, VPS25, CBLB, CBLC, ZGPAT, ZFYVE28 |
| negative regulation of epinephrine secretion | biological process | PTGS1, CRH, ADRA2A, ADRA2B, ADRA2C |
| negative regulation of epithelial cell apoptotic process | biological process | NUPR1, MDK, CFLAR, YAP1 |
| negative regulation of epithelial cell differentiation | biological process | IFNG, SOX9, CCND1, SMO, ZEB1, YAP1, TBX3, DLL1, CAV1 |
| negative regulation of epithelial cell migration | biological process | IL4, SEMA3A, PTPRR, STRAP, ADIPOR1, MARVELD3, DAB2IP, CORO1C, PTPN23, PFN2, PTPRG, EVL, TACSTD2, MCC, DUSP10 |
| negative regulation of epithelial cell proliferation | biological process | TGFB1, SOX9, ESR2, FGFR2, PTEN, TGFBR3, RB1, BMP4, SOX2, PEX2, IFT57, ISL1, IFT74, RGN, IFT52, STRAP, MARVELD3, MAGED1, PTN, PPARD, DAB2IP, NKX3-1, AQP11, NUPR1, WFDC1, TINF2, HPN, MEF2C, MTSS1, CDKN2B, MEN1, CDC73, EREG, RIDA, TGFB2, CDK6, DLG1, SAV1, CDKN1B, IFT80, EPPK1, ATF2, NKX2-8, SFRP2, IFT122, WNT10B, MCC, CDKN1C, GPC3, PTCH1, LIMS2, IFT172, GDF5, IL26, DUSP10 |
| negative regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | NFIB |
| negative regulation of epithelial cell proliferation involved in prostate gland development | biological process | WDR77, NKX3-1, CDKN1B, SERPINF1, EAF2 |
| negative regulation of epithelial to mesenchymal transition | biological process | OVOL2, PPP2CA, STRAP, ADIPOR1, DAB2IP, EFNA1, SPRY1, FOXA1, SPRED1, HPN, GATA3, SDHAF2, BMP5, TBX5, MAD2L2, TRIM62, SPRY2, SFRP2, VASN, LDLRAD4, NKX2-1, FOXA2 |
| negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological process | TGFB2 |
| negative regulation of epithelium regeneration | biological process | DUSP10 |
| negative regulation of ER-associated ubiquitin-dependent protein catabolic process | biological process | SGTA, USP14, SVIP |
| negative regulation of ERAD pathway | biological process | AQP11, USP25, UBXN1 |
| negative regulation of ERBB signaling pathway | biological process | LGMN, PTPN12, PTPN18 |
| negative regulation of ERBB4 signaling pathway | biological process | ACP4 |
| negative regulation of ERK1 and ERK2 cascade | biological process | LIF, ATF3, NDRG2, TLR4, GSTP1, PTEN, EZR, DUSP6, SPRY4, KLF4, PTPRR, C3orf33, SMAD4, PIN1, LMO3, ERRFI1, XBP1, DAB2IP, SLC9A3R1, EPHB2, EIF3A, SPRY1, PTPN2, TIMP3, SPRED1, ADIPOQ, TBC1D10C, FBLN1, WNK2, PTPRC, RAPGEF1, CHRNA10, VRK3, ITGB1BP1, CRYBA1, DLG1, GBP1, ABL1, LYN, PTPN1, FLCN, SEMA6A, DUSP1, TNIP1, CNKSR3, EMILIN1, SPRY2, PSCA, DUSP3, NLRP12, RGS14, CSK, DUSP26, SYNJ2BP, GPER1, DUSP10 |
| negative regulation of erythrocyte apoptotic process | biological process | EPO |
| negative regulation of erythrocyte differentiation | biological process | HOXA5, STAT5B, GAS2L1, ZFP36, ZFP36L1, LDB1, KLF13, NCAPG2 |
| negative regulation of establishment of blood-brain barrier | biological process | TTPA, TRPV1 |
| negative regulation of establishment of endothelial barrier | biological process | S1PR3 |
| negative regulation of establishment of protein localization | biological process | CORO2B |
| negative regulation of establishment of T cell polarity | biological process | RIPOR2 |
| negative regulation of estrogen receptor binding | biological process | NKX3-1, RUVBL2, LEF1 |
| negative regulation of excitatory postsynaptic potential | biological process | PTEN, NLGN4X, CELF4, S1PR2, TMEM25, EIF4A3, LRRK2 |
| negative regulation of execution phase of apoptosis | biological process | CIDEA, FZD3, CXCR3, BCL2L1, DFFA |
| negative regulation of exit from mitosis | biological process | RGCC |
| negative regulation of exo-alpha-sialidase activity | biological process | APCS |
| negative regulation of exocytosis | biological process | IL1RAPL1, SNCA, ANXA1, STXBP6, RSC1A1 |
| negative regulation of exosomal secretion | biological process | VPS4B, PRKN, RAB7A |
| negative regulation of extracellular matrix assembly | biological process | ANTXR1 |
| negative regulation of extracellular matrix constituent secretion | biological process | NOTCH1, ADTRP |
| negative regulation of extracellular matrix disassembly | biological process | TGFB1, DPP4 |
| negative regulation of extrinsic apoptotic signaling pathway | biological process | IL4, AR, GSTP1, PARK7, IGF1, ITGAV, SRC, ITGA6, TCF7L2, RB1CC1, SIAH2, IL7, GCLC, ACVR1, PHIP, CTTN, SH3RF1, THBS1, RELA, CFLAR, ZMYND11, TGFBR1, BIRC6, YAP1, PELI3, SCG2, HTT, NOL3, NRP1, PAK5 |
| negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | TNF, IL1B, BCL2, TERT, AKT1, IL1A, NRG1, HSPA1A, HSPA1B, MCL1, GDNF, CX3CL1, IL7, CTNNA1, STRADB, COL2A1, IFI6, PF4, EYA4, MAPK7, SGK3, BCL2L1, MAP2K5, EYA1, UNC5B, EYA2, ZC3HC1, FGF10, GATA1 |
| negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | ICAM1, FAS, NOS3, BRCA1, TNFSF10, SERPINE1, HMOX1, FASLG, CASP8, GPX1, HGF, RAF1, RNF34, DDX3X, FAIM, FGG, TNFRSF10B, FADD, FGB, CFLAR, BMP5, ITPRIP, ARHGEF2, PEA15, FAIM2, TMBIM1, BCL2L1, TRADD, SFRP2, TNFRSF10A, FGA, TRAF2, SCRT2 |
| negative regulation of eye photoreceptor cell development | biological process | DIO3 |
| negative regulation of eye pigmentation | biological process | IHH |
| negative regulation of Fas signaling pathway | biological process | TMBIM1 |
| negative regulation of FasL production | biological process | JAK3 |
| negative regulation of fat cell differentiation | biological process | TGFB1, TNF, IL6, E2F1, FOXO1, ZFPM2, DDIT3, TRIB3, ASXL1, JDP2, RUNX1T1, BBS12, TLCD3B, ADIPOQ, WNT3A, GATA3, SIRT2, TGFB1I1, ENPP1, RORA, ZADH2, GPS2, ID4, ZFP36L2, SORT1, INSIG1, TRIO, GATA2, ANKRD26, MSX2, TRIB2, ARNTL, WNT10B, WWTR1, MMP11, LRP3, JAG1, CCN4, SMAD3, ZFPM1, CCDC85B, GPER1 |
| negative regulation of fat cell proliferation | biological process | E2F1, TFDP1, E2F3, PER2, GATA2 |
| negative regulation of fatty acid beta-oxidation | biological process | AKT1, CNR1, MFSD2A, ACACB |
| negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase | biological process | ETFBKMT |
| negative regulation of fatty acid biosynthetic process | biological process | BRCA1, ERLIN1, TRIB3, ACADVL, WDTC1, ACADL, APOC1, INSIG1, ERLIN2, CEACAM1, APOC3, INSIG2 |
| negative regulation of fatty acid metabolic process | biological process | UGT1A8, UGT1A4, SLC22A13, NCOR1, INS, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| negative regulation of fatty acid oxidation | biological process | SIRT4, DGAT2, ACADVL, ACADL, APPL2, ACACB |
| negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | CD47, APPL1 |
| negative regulation of feeding behavior | biological process | ESR2, TRH, NMU, UCN, INS |
| negative regulation of female gonad development | biological process | WT1, NR5A1, ZFPM2 |
| negative regulation of female receptivity | biological process | THRB, PPP1R1B, AVP |
| negative regulation of fermentation | biological process | CAVIN3 |
| negative regulation of fibrinolysis | biological process | SERPINE1, USF1, THBD, THBS1, SERPINF2, PLG, HRG, F2, APOH |
| negative regulation of fibroblast apoptotic process | biological process | GAS6, PIK3CA, API5, CFDP1, PIK3CG, CHD8 |
| negative regulation of fibroblast growth factor production | biological process | RGCC, WNT11 |
| negative regulation of fibroblast growth factor receptor signaling pathway | biological process | SPRY1, WNT4, THBS1, SPRY2, SULF1, NGFR, FGF2, GPC1, SULF2, SPRY3 |
| negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation | biological process | FUZ |
| negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation | biological process | GATA3 |
| negative regulation of fibroblast migration | biological process | ITGB1BP1, MACIR, HYAL2, ARHGAP4, FGF2, HAS1, CYGB |
| negative regulation of fibroblast proliferation | biological process | TP53, BAX, GSTP1, MYC, PEX2, EMD, PAWR, DAB2IP, TP53INP1, MORC3, FTH1, NUPR1, FBXO4, SKI, TRIM32, CDC73, MED31, MED25, DACH1, PARP10, NF1, LTA |
| negative regulation of filopodium assembly | biological process | NRXN1, SRGAP2C, PRKCD, CAPZB, ARHGAP44 |
| negative regulation of flagellated sperm motility | biological process | SEMG1, EPPIN, SEMG2, RGN |
| negative regulation of focal adhesion assembly | biological process | PTEN, SRC, DUSP22, CORO1C, DLC1, RCC2, THBS1, APOD, ITGB1BP1, PHLDB2, MMP14, ARHGAP6, BCAS3, LRP1, CLASP2, DMTN, ACVRL1, FAM107A |
| negative regulation of follicle-stimulating hormone secretion | biological process | INHBA, INHA |
| negative regulation of forebrain neuron differentiation | biological process | HES1 |
| negative regulation of formation of translation preinitiation complex | biological process | RPL13A |
| negative regulation of G protein-coupled receptor internalization | biological process | NECAB2 |
| negative regulation of G-protein coupled receptor protein signaling pathway | biological process | CXCL8, CCL5, PLEK, MGRN1, RGS2, CRY1, YWHAB, RGS14, RPH3AL, RGS4, RPGRIP1L, RGS13 |
| negative regulation of G0 to G1 transition | biological process | EED, TFDP1, RBBP8, MAX, PHC1, CBX3, RBBP7, RRM2, DAB2IP, PCGF2, SUZ12, RYBP, EHMT2, EHMT1, BMI1, RBBP4, E2F6, EPC1, TFDP2, MGA, PHC3, L3MBTL2, FOXO4, RING1, CBX5, RNF2 |
| negative regulation of G1/S transition of mitotic cell cycle | biological process | BCL2, EZH2, PTEN, RB1, RBL1, RBL2, GJC2, ZNF655, KLF4, KANK2, FHL1, GPNMB, CDK2AP2, PRMT2, PKD2, SLFN11, CDKN2B, CDKN2D, CDC73, CDK6, CTDSP2, CDKN2C, CTDSPL, CDKN1A, GFI1B, E2F7, CTDSP1, DACT1, MYO16, FBXO7, ZC3H12D, FAM107A, CCL2 |
| negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter | biological process | NACC2 |
| negative regulation of G2/M transition of mitotic cell cycle | biological process | PSMB1, PSMB5, PSMC2, PSMA8, USP47, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, PSMD14, PSMD7, PSMB6, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, CUL1, FHL1, PSMB8, PSMD4, PSMC3, PSMA6, GPR132, RFPL1, RAD21, PSMD12, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, PSMD5, PSMF1, PSMB3, PSMD3, PSMC1, RBX1, MIIP, AVEN, FBXL7, PINX1, PSMD13, PSMB10 |
| negative regulation of gamma-aminobutyric acid secretion | biological process | ABAT, HTR1B |
| negative regulation of gap junction assembly | biological process | ACE |
| negative regulation of gastric acid secretion | biological process | OXTR, OXT, NMU, UCN, TFF2, PTGER3 |
| negative regulation of gastric emptying | biological process | PTGER1, NMU |
| negative regulation of gastrin-induced gastric acid secretion | biological process | SCT |
| negative regulation of gene expression | biological process | TGFB1, TNF, IFNG, IL1B, ESR1, PGR, SOX9, BAK1, TERT, CCNB1, AKT1, MDM2, SRY, EZH2, MBD1, FGFR1, CTNNB1, PARK7, INSR, RB1, BMP4, MIF, CD46, NOS2, XDH, GJA1, CDC42, SHH, AIF1, MAEL, RBL1, CCN2, RBL2, OVOL2, TBK1, KLF4, MAX, PAWR, OLFM1, PDCD10, BBS2, ANXA7, CCR1, ZC3H12A, RNASEH2B, ZNF503, CCDC3, GATA5, AGO4, PTRH2, LGALS9, ACVR1B, HNRNPD, FBXW7, SETDB2, ZMPSTE24, PDGFB, CRYAB, RACK1, TP53INP1, NKX3-1, SH3GL2, CLDN5, KDM4A, CCL3, IQGAP3, PRKN, ROCK2, CD34, NRXN1, LGMN, C1QTNF3, MKKS, WDR35, LDLR, WNT4, DIP2A, HAVCR2, FERMT1, ADNP, AGO3, ZNF281, ROS1, PC, NOTCH1, RUNX1, REST, PICALM, PARP14, FOXP1, ZBTB20, PRDM1, SLC2A10, CRH, GATA3, ID3, MEF2C, TIPARP, BBS4, SAMD7, MORC1, PTPN22, PSEN1, AFF2, UCN, STOX1, SMO, PINK1, CD3E, SOX11, REL, RBMS3, STC2, TAF1, YY1, MAP2K2, MECP2, TGFB2, GAS2L1, PPP3CA, CPNE1, WWP2, NDFIP1, NDFIP2, AGO2, POU3F2, OPRD1, SETDB1, MYADM, SNX12, TNRC6B, CNPY2, GATA2, ITGB8, YAP1, PRKAA2, TCEAL1, SMAD2, TNRC6A, FLCN, SMCR8, CITED2, TNRC6C, HEY2, CDKN1A, POU4F1, TGIF1, SLC24A3, MOV10, EMILIN1, |
| negative regulation of gene expression, epigenetic | biological process | DNMT1, EZH2, DNMT3B, HIST1H4A, EED, PHF1, SPI1, RBBP7, MACROH2A2, SUZ12, JARID2, TASOR, BMI1, RBBP4, MACROH2A1, EPC1, CREBZF, PPHLN1, MTF2, H3C1, MORC2, AEBP2, LHX2, H3-3A, H4-16, H3C13 |
| negative regulation of gene silencing by miRNA | biological process | TGFB1 |
| negative regulation of germinal center formation | biological process | FOXJ1, RC3H1 |
| negative regulation of glial cell apoptotic process | biological process | PRKCH, PRKCD, DLL1, TRAF2, CCL2 |
| negative regulation of glial cell differentiation | biological process | LIN28A |
| negative regulation of glial cell migration | biological process | IDH2, ATP1B2 |
| negative regulation of glial cell proliferation | biological process | PTN, HES1, NOTCH1, SOX11, IDH2 |
| negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation | biological process | GATA3 |
| negative regulation of gliogenesis | biological process | PITX3 |
| negative regulation of glomerular filtration | biological process | F2R, GJA5, PTPRO |
| negative regulation of glomerular filtration by angiotensin | biological process | CYBA |
| negative regulation of glomerular mesangial cell proliferation | biological process | BMP7, BMP4 |
| negative regulation of glomerulus development | biological process | BMP4 |
| negative regulation of glucagon secretion | biological process | LEP, CRH, FAM3D, CARTPT |
| negative regulation of glucocorticoid biosynthetic process | biological process | ATP1A1 |
| negative regulation of glucocorticoid mediated signaling pathway | biological process | CREBRF |
| negative regulation of glucocorticoid receptor signaling pathway | biological process | CLOCK, PER1, CRY1, ARNTL, CRY2 |
| negative regulation of glucocorticoid secretion | biological process | CRY1 |
| negative regulation of glucokinase activity | biological process | COX11, MIDN, PRKN, FOXA2 |
| negative regulation of gluconeogenesis | biological process | IL6, LEPR, CLK2, C1QTNF3, ADIPOQ, MAEA, FAM3C, EP300, PGP, MST1, CRY1, SOGA1, INS, GCK, SIK1, FAM3A, SERPINA12 |
| negative regulation of glucose catabolic process to lactate via pyruvate | biological process | TIGAR, SLC25A12, TP53 |
| negative regulation of glucose import | biological process | TNF, ESR1, LEP, SELENOS, GRB10, ENPP1, PID1, PEA15, STXBP3, SIRT6, APPL2, OSTN |
| negative regulation of glucose transport | biological process | IL1B, FABP5, PRKCB, INPP5K, RSC1A1 |
| negative regulation of glucuronosyltransferase activity | biological process | UGT1A8, UGT1A4, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| negative regulation of glutamate metabolic process | biological process | ATCAY |
| negative regulation of glutamate secretion | biological process | IL1B, TRH, HRH3, GRM7, NPY5R |
| negative regulation of glutamine transport | biological process | LEP |
| negative regulation of glycine import across plasma membrane | biological process | RGS2, RGS4 |
| negative regulation of glycogen (starch) synthase activity | biological process | GSK3B, INPP5K |
| negative regulation of glycogen biosynthetic process | biological process | GSK3B, SELENOS, PASK, GRB10, ENPP1, INPP5K |
| negative regulation of glycogen catabolic process | biological process | INS |
| negative regulation of glycolytic process | biological process | STAT3, HDAC4, PPARGC1A, NUPR1, FBP1, CBFA2T3, NCOR1, SIRT6, MYOG, ACTN3, TIGAR, PPARA |
| negative regulation of glycolytic process through fructose-6-phosphate | biological process | SLC4A1 |
| negative regulation of glycoprotein metabolic process | biological process | APCS |
| negative regulation of Golgi to plasma membrane protein transport | biological process | LYPLA1, ANXA13, CSK, PKDCC, RSC1A1 |
| negative regulation of granulocyte colony-stimulating factor production | biological process | HAVCR2 |
| negative regulation of granulocyte differentiation | biological process | ADIPOQ, RUNX1, C1QC, ZBTB46, CEACAM1, PRDM16, INPP5D, RARA |
| negative regulation of granulocyte macrophage colony-stimulating factor production | biological process | CD84 |
| negative regulation of growth | biological process | HIF1A, MT1A, MT1F, MT1G, MT1M, PNPT1, MT1H, MT2A, MT1E, MT1X, MT1B, ALOX15B, IGFBP5, GPC3, PTK6, ING5, ING4 |
| negative regulation of growth hormone receptor signaling pathway | biological process | LEPROT |
| negative regulation of growth hormone secretion | biological process | PTPN11, KALRN |
| negative regulation of growth of symbiont in host | biological process | TNF, IFNG, IL10, ELANE |
| negative regulation of growth of symbiont involved in interaction with host | biological process | IFNG |
| negative regulation of growth rate | biological process | NOTCH1, TMPRSS4 |
| negative regulation of GTP binding | biological process | C9orf72 |
| negative regulation of GTPase activity | biological process | FICD, SH3BP4, ARFGEF1, IQGAP1, IQGAP2, RGN, PDE6D, DAB2IP, ARL2, SPRY1, TSC1, MKKS, GPSM1, AMOT, RCC2, IPO5, DGKI, BBS4, WNK1, TMED2, GPS2, PTPRN2, CPEB2, F11R, RDX, BCAS3, SPRY2, RTKN, HRAS, GPS1, RRP1B, CDC42SE1, PLXNB3, RASA4, RHOH, GMIP, ARRB2, SLIT2, LRRK2 |
| negative regulation of guanyl-nucleotide exchange factor activity | biological process | GPSM1, STMN1, EIF2S1 |
| negative regulation of guanylate cyclase activity | biological process | HPCA, PDZD3, RD3 |
| negative regulation of hair cycle | biological process | TRPV3 |
| negative regulation of hair follicle development | biological process | SMO, NGFR |
| negative regulation of hair follicle placode formation | biological process | DKK4 |
| negative regulation of heart contraction | biological process | IL2, ATP2A2, JAK2, ATP1A2, PLN, PDE4D, ATP1A1 |
| negative regulation of heart induction by canonical Wnt signaling pathway | biological process | WNT3A |
| negative regulation of heart looping | biological process | TBX2 |
| negative regulation of heart rate | biological process | TAC1, SRI, PLN, FKBP1B, NPFF, RNLS, SPTBN4, TRPV1 |
| negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure | biological process | ADRA1A |
| negative regulation of heat generation | biological process | ARRDC3 |
| negative regulation of helicase activity | biological process | TP53, IFIT1 |
| negative regulation of hematopoietic progenitor cell differentiation | biological process | MIXL1 |
| negative regulation of hematopoietic stem cell differentiation | biological process | NFE2L2, N4BP2L2 |
| negative regulation of hemoglobin biosynthetic process | biological process | EIF2AK1 |
| negative regulation of hemopoiesis | biological process | IL17D |
| negative regulation of hemostasis | biological process | COMP |
| negative regulation of hepatic stellate cell activation | biological process | GCLC, CYGB |
| negative regulation of hepatocyte apoptotic process | biological process | CFLAR |
| negative regulation of hepatocyte differentiation | biological process | FRZB |
| negative regulation of hepatocyte growth factor receptor signaling pathway | biological process | ADAMTS12 |
| negative regulation of hepatocyte proliferation | biological process | FBXW7, CEACAM1, LIMS2 |
| negative regulation of heterotypic cell-cell adhesion | biological process | IL1RN, KLF4, ADIPOQ, WNK1, APOA1, MBP, MAPK7, MYADM, MAP2K5 |
| negative regulation of hh target transcription factor activity | biological process | ENPP1 |
| negative regulation of high voltage-gated calcium channel activity | biological process | GEM, REM1, DYSF, RRAD |
| negative regulation of high-density lipoprotein particle clearance | biological process | APOC3 |
| negative regulation of hippo signaling | biological process | MARK3, DLG5, AJUBA, WWC1, MAP2K3, WWC3, WTIP, VGLL4, LIMD1 |
| negative regulation of hippocampal neuron apoptotic process | biological process | CX3CR1 |
| negative regulation of histone acetylation | biological process | BRCA1, SNCA, TAF7, TWIST1, CTBP1, SET, NOC2L |
| negative regulation of histone deacetylase activity | biological process | SPHK2, KDM5A |
| negative regulation of histone deacetylation | biological process | SPHK2, SKI, UCN |
| negative regulation of histone H2A K63-linked ubiquitination | biological process | UBR5, TRIP12 |
| negative regulation of histone H3-K27 acetylation | biological process | SIN3A |
| negative regulation of histone H3-K27 methylation | biological process | PHF1, MACROH2A1, MTF2, EZHIP |
| negative regulation of histone H3-K36 methylation | biological process | BCOR, FH |
| negative regulation of histone H3-K4 methylation | biological process | BRCA1, BCOR, WDR5, MACROH2A1 |
| negative regulation of histone H3-K79 methylation | biological process | MLLT6 |
| negative regulation of histone H3-K9 acetylation | biological process | ZNF451 |
| negative regulation of histone H3-K9 dimethylation | biological process | SMARCB1 |
| negative regulation of histone H3-K9 methylation | biological process | BRCA1, DNMT1, DNMT3B, PAX5 |
| negative regulation of histone H3-K9 trimethylation | biological process | KDM4C, KDM4D, SMARCB1 |
| negative regulation of histone H4 acetylation | biological process | SPI1, TAF7, CTBP1 |
| negative regulation of histone H4-K16 acetylation | biological process | ATG5 |
| negative regulation of histone methylation | biological process | JARID2 |
| negative regulation of histone phosphorylation | biological process | UBE2B, TWIST1, MACROH2A1 |
| negative regulation of homotypic cell-cell adhesion | biological process | RDX, ZNF703 |
| negative regulation of hormone secretion | biological process | IL6, LIF, IL11, PTPN11, ADIPOQ, FGF23, UCN, OSM, NMB, EDN1 |
| negative regulation of humoral immune response mediated by circulating immunoglobulin | biological process | FOXJ1, PTPN6, FCGR2B |
| negative regulation of hyaluronan biosynthetic process | biological process | TGFB1, SMPD3, CLTC, AP2A1 |
| negative regulation of hydrogen peroxide biosynthetic process | biological process | STAT3, CTNS, MPV17L |
| negative regulation of hydrogen peroxide catabolic process | biological process | MT3, HP |
| negative regulation of hydrogen peroxide metabolic process | biological process | HDAC6 |
| negative regulation of hydrogen peroxide-induced cell death | biological process | NFE2L2, PARK7, GPR37L1, PSAP, PYCR1, PDE8A, LRRK2 |
| negative regulation of hydrogen peroxide-induced neuron death | biological process | PARK7, RACK1, NR4A3, FBXO7 |
| negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway | biological process | PARK7, PINK1 |
| negative regulation of hydrogen peroxide-mediated programmed cell death | biological process | HGF |
| negative regulation of hydrolase activity | biological process | NOS3, LEPR, SERPINA5, ATP5IF1, APOA1, PRKCZ, CAMK2A |
| negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway | biological process | TMBIM6, PINK1, HYOU1, NOL3 |
| negative regulation of I-kappaB kinase/NF-kappaB signaling | biological process | ESR1, STAT1, CASP8, GSTP1, OPTN, TLE1, TNIP3, PER1, PPM1B, ZC3H12A, TRIM39, NLRX1, DAB2IP, ADIPOQ, OTUD7A, RORA, TANK, NR1H4, RIOK3, ABL1, ZMYND11, TRIM59, MAPKBP1, CARD19, PPM1A, ASH1L, NR1D1, TNIP1, CARD8, CCDC22, NLRP12, PYCARD, USP10, RHOH, OTUD7B, CACTIN |
| negative regulation of icosanoid secretion | biological process | CYP4F2 |
| negative regulation of immature T cell proliferation | biological process | GNRH1 |
| negative regulation of immature T cell proliferation in thymus | biological process | ERBB2, CDKN2A, BMP4, TMEM131L, IHH |
| negative regulation of immune response | biological process | TGFB1, IL2RA, HLA-G, SPINK5, COL3A1, CTLA4, FCGR2B, LYN, AMBP, INPP5D |
| negative regulation of immune response to tumor cell | biological process | HAVCR2 |
| negative regulation of immune system process | biological process | SOX9 |
| negative regulation of immunoglobulin production | biological process | IL13RA2, FCGR2B, PRKDC, ZPBP2 |
| negative regulation of immunoglobulin secretion | biological process | IL33, TMBIM6, CD22 |
| negative regulation of immunological synapse formation | biological process | HAVCR2 |
| negative regulation of inclusion body assembly | biological process | HSPA2, HSPA1A, HSPA1B, DNAJA4, DNAJB8, SACS, DNAJB1, DNAJB2 |
| negative regulation of inflammatory response | biological process | SERPINC1, APOE, TNFRSF1A, TNFRSF1B, IL10, GHRL, KRT1, IL2RA, HGF, IL2, MEFV, ELANE, NR1H3, GBA, SAA1, NR1D2, LRFN5, SELENOS, KLF4, ISL1, NLRX1, SOCS5, PROC, PPARD, CALCRL, IL22RA2, TNFAIP6, BCR, PTPN2, ABR, C1QTNF3, IL13, ADIPOQ, GHSR, WFDC1, ENPP3, NT5E, GATA3, TEK, OTULIN, RORA, ETS1, APOA1, GPS2, MACIR, NLRP3, NR1H4, SHARPIN, MAPK7, PTGIS, NDFIP1, ALOX5, PTGER4, PRKCD, ADA, FNDC4, ASH1L, NR1D1, SMPDL3B, CCN3, NLRP12, TNFAIP8L2, FPR2, CDH5, MFHAS1, FOXF1, AOAH, SERPINF1, FEM1A, MVK, PPARA, METRNL, ADORA2A, SMAD3, SOCS3, VPS35, Grn, TYRO3, GPER1 |
| negative regulation of inflammatory response to antigenic stimulus | biological process | GPX1, PSMA1, PSMB4, GPR17 |
| negative regulation of inflammatory response to wounding | biological process | MDK, SIGLEC10 |
| negative regulation of innate immune response | biological process | NLRX1, HAVCR2, DHX58, IRAK3, IFI16, TRAFD1, MUL1, DRD2, CACTIN, Grn, TYRO3 |
| negative regulation of inner ear auditory receptor cell differentiation | biological process | HES1, NOTCH1, DLL1 |
| negative regulation of inner ear receptor cell differentiation | biological process | HES1 |
| negative regulation of inositol phosphate biosynthetic process | biological process | PLEK |
| negative regulation of insulin receptor signaling pathway | biological process | IL1B, KANK1, TNS2, NCK1, RPS6KB1, GRB10, PTPN2, TSC1, SOCS1, RELA, PRKCQ, ENPP1, IRS1, PID1, GRB7, PRKCB, INPP5K, PRKCZ, PRKCD, PTPN1, PTPRE, GPR21, MSTN, TSC2, TRIM72, SOCS3, AHSG, NCOA5 |
| negative regulation of insulin secretion | biological process | GHRL, PTPN11, HADH, MIDN, SIRT4, PRKN, SYTL4, GHSR, REST, IRS1, ADRA2A, FAM3D, ACVR1C, KCNB1, PPP3CA, PSMD9, NPFF, SREBF1, CCN3, PFKL, VSNL1, DRD2, STXBP5L |
| negative regulation of insulin secretion involved in cellular response to glucose stimulus | biological process | NDUFAF2, ENY2, HMGCR, ADRA2A, FKBP1B, KLF7, PIM3 |
| negative regulation of insulin-like growth factor receptor signaling pathway | biological process | NKX3-1, BMP5, BMP2, CILP, IGFBP5, TRIM72 |
| negative regulation of integrin activation | biological process | KIF14, JAM3, PTGER4 |
| negative regulation of integrin biosynthetic process | biological process | AR, TMEFF2 |
| negative regulation of integrin-mediated signaling pathway | biological process | CTNNA1, SLC2A10, PHACTR4 |
| negative regulation of interferon-alpha biosynthetic process | biological process | IL10 |
| negative regulation of interferon-alpha production | biological process | HAVCR2, LILRA4, PTPRS |
| negative regulation of interferon-beta production | biological process | PPM1B, TRAF3IP1, NLRX1, REL, YY1, TRAIP, PYCARD, PTPRS, RELB, CACTIN |
| negative regulation of interferon-gamma biosynthetic process | biological process | INHBA, INHA |
| negative regulation of interferon-gamma production | biological process | HLA-DRB1, IL10, AXL, GAS6, TLR4, C1QBP, IL33, PRNP, LGALS9, IL20RB, HAVCR2, CD274, GATA3, HMGB1, ZNF683, NR1H4, CD96, IL1RL1, PDCD1LG2, TNFSF4, PGLYRP2, LGALS9B, VSIR, RARA |
| negative regulation of interferon-gamma secretion | biological process | ZC3H12A, IL36RN, NR1H4 |
| negative regulation of interferon-gamma-mediated signaling pathway | biological process | PPARG, NR1H3, PTPN2, PARP14, OTOP1, NR1H2 |
| negative regulation of interleukin-1 beta production | biological process | GHRL, GSTP1, MEFV, ERRFI1, GHSR, CX3CR1, TREM2, CD33, FFAR1, ARRB2 |
| negative regulation of interleukin-1 beta secretion | biological process | ZC3H12A, SERPINB1, NLRP7, PYDC1, APOA1, NLRP3, CPTP, PML, CARD18, CARD16, CARD8 |
| negative regulation of interleukin-1 production | biological process | IL10, NR1H4, CEACAM1 |
| negative regulation of interleukin-1 secretion | biological process | GAS6, PML, NLRP12 |
| negative regulation of interleukin-1-mediated signaling pathway | biological process | IL1RN, OTUD4, ZNF675 |
| negative regulation of interleukin-10 biosynthetic process | biological process | TYROBP, TRIB2 |
| negative regulation of interleukin-10 production | biological process | IL23A, IDO1, FCGR2B, CD274, EPX, IL23R, PDCD1LG2, DLL1, JAK3, VSIR, MMP8, AGER |
| negative regulation of interleukin-10 secretion | biological process | TNFRSF9, TNFRSF21 |
| negative regulation of interleukin-12 production | biological process | IL10, C1QBP, MEFV, THBS1, PIBF1, IRAK3, SLAMF1, CMKLR1, ARRB2, JAK3 |
| negative regulation of interleukin-12 secretion | biological process | LILRA5, TNFRSF9, CCR7 |
| negative regulation of interleukin-13 production | biological process | IFNL1, LEF1 |
| negative regulation of interleukin-13 secretion | biological process | LILRA5, TNFRSF21, IFNA2 |
| negative regulation of interleukin-17 production | biological process | TGFB1, IFNG, IL12A, TLR4, PRNP, IL36RN, TUSC2, TNFSF4, NCKAP1L, VSIR |
| negative regulation of interleukin-17 secretion | biological process | IL27RA |
| negative regulation of interleukin-18 production | biological process | IL10, CD84 |
| negative regulation of interleukin-2 biosynthetic process | biological process | PTPRC, ZFP36, SFTPD |
| negative regulation of interleukin-2 production | biological process | PRNP, IL20RB, HAVCR2, HOMER2, GATA3, KAT5, NR1H4, HDAC7, VSIG4, TBX21, NAV3, HOMER3 |
| negative regulation of interleukin-2 secretion | biological process | EZR, CD34, GBP1 |
| negative regulation of interleukin-2-mediated signaling pathway | biological process | PTPN2 |
| negative regulation of interleukin-23 production | biological process | TLR4, RAC1 |
| negative regulation of interleukin-3 production | biological process | HAVCR2 |
| negative regulation of interleukin-4 biosynthetic process | biological process | ZFPM1 |
| negative regulation of interleukin-4 production | biological process | CD83, NDFIP1, LEF1 |
| negative regulation of interleukin-4-mediated signaling pathway | biological process | PTPN2 |
| negative regulation of interleukin-5 production | biological process | EPX, IFNL1, LEF1 |
| negative regulation of interleukin-5 secretion | biological process | TNFRSF21, IFNA2 |
| negative regulation of interleukin-6 biosynthetic process | biological process | GHRL, FOXJ1, GHSR, NLRP12, INPP5D |
| negative regulation of interleukin-6 production | biological process | TNF, IL10, GAS6, TLR4, HGF, GBA, SELENOS, ZC3H12A, NLRX1, SOCS5, ORM1, PTPN6, HAVCR2, IRAK3, IL36RN, NR1H4, TLR9, BPI, NCKAP1L, SLAMF1, CSK, KLF2, ARRB2 |
| negative regulation of interleukin-6 secretion | biological process | GAS6, BANK1, ZC3H12A, C1QTNF3, PTPN22, CD200R1, C5AR2, IL27RA |
| negative regulation of interleukin-6-mediated signaling pathway | biological process | IL6ST, PTPN2 |
| negative regulation of interleukin-8 biosynthetic process | biological process | ELANE, KLF4, BCL3, MAP2K5 |
| negative regulation of interleukin-8 production | biological process | IL6R, IL10, TLR9, BPI, CD33, OTUD7B, CACTIN |
| negative regulation of interleukin-8 secretion | biological process | ANXA4, ANXA1, PTPN22, MAPKBP1, SSC5D, TLR6 |
| negative regulation of intestinal absorption | biological process | HAMP |
| negative regulation of intracellular calcium activated chloride channel activity | biological process | ANO9 |
| negative regulation of intracellular cholesterol transport | biological process | ABCA2 |
| negative regulation of intracellular estrogen receptor signaling pathway | biological process | BRCA1, ISL1, CNOT1, KANK2, PHB2, CNOT9, STRN3, LBH, CNOT2, ZNF366, FOXH1 |
| negative regulation of intracellular protein transport | biological process | ADIPOQ |
| negative regulation of intracellular signal transduction | biological process | LYN |
| negative regulation of intracellular steroid hormone receptor signaling pathway | biological process | NR0B1, CALR |
| negative regulation of intracellular transport | biological process | CRYAB, CRYAA, MAP1B |
| negative regulation of intracellular transport of viral material | biological process | BST2, TRIM15 |
| negative regulation of intralumenal vesicle formation | biological process | PRKN, RAB7A |
| negative regulation of intrinsic apoptotic signaling pathway | biological process | BCL2, MMP9, BCL2L2, VDAC2, PLAUR, SRC, MCL1, PARL, DDX3X, IVNS1ABP, MAPK8IP1, HERPUD1, PINK1, URI1, PPIF, BCL2L1, FIGNL1, BCL2L10, NOC2L |
| negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | PTTG1IP, RRM2B, PRKN, RRN3 |
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | biological process | CLU, USP47, TMEM161A, ATAD5, TRIM32, ACKR3, CDKN2D, BID, CCAR2, TPT1, BCL2L1, SFRP2, CXCL12 |
| negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | CD44, MIF, MUC1, BCL2L12, CD74, ZNF385A, TAF9B, MARCHF7, ELL3, ATAD5, ING2, TRIAP1, TAF9 |
| negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide | biological process | PINK1, TRAP1 |
| negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress | biological process | YBX3, BDKRB2, ARHGEF2, EPO |
| negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator | biological process | BDKRB2 |
| negative regulation of inward rectifier potassium channel activity | biological process | CAV1 |
| negative regulation of iodide transmembrane transport | biological process | MTOR |
| negative regulation of ion transmembrane transport | biological process | YWHAQ, CRBN, SLC26A5 |
| negative regulation of ion transmembrane transporter activity | biological process | HAMP |
| negative regulation of ion transport | biological process | BEST3, PXK, CNR1 |
| negative regulation of IRE1-mediated unfolded protein response | biological process | DNAJB9, BFAR |
| negative regulation of iron export across plasma membrane | biological process | HAMP |
| negative regulation of iron ion import across plasma membrane | biological process | ISCU |
| negative regulation of iron ion transmembrane transport | biological process | ATP7A, HAMP |
| negative regulation of iron ion transmembrane transporter activity | biological process | HAMP |
| negative regulation of isotype switching | biological process | PARP3 |
| negative regulation of isotype switching to IgA isotypes | biological process | THOC1 |
| negative regulation of isotype switching to IgE isotypes | biological process | BCL6, NDFIP1 |
| negative regulation of JAK-STAT cascade | biological process | DCN, FLRT3, NF2, LRRC4C, SOCS2, SH2B3, ADIPOR1, BCL3, HGS, SOCS1, NEUROD1, LEPROT, VHL, SOCS3, CAV1 |
| negative regulation of JNK cascade | biological process | AKT1, ITCH, PER1, DUSP19, MARVELD3, MAPK8IP1, PRKN, AIDA, TAOK3, MEN1, PINK1, GPS2, CYLD, ZMYND11, SH3RF2, HDAC3, NCOR1, DACT1, DUSP3, MECOM, FKTN, AMBP, ZNF675, DUSP10 |
| negative regulation of JUN kinase activity | biological process | GSTP1, DUSP19, MAPK8IP1, PDCD4, AIDA, PTPN22, HIPK3, SERPINB3, SFRP2, ZNF675, DUSP10 |
| negative regulation of keratinocyte differentiation | biological process | SRSF6, TP63, OVOL2, REG3A, REG3G, HOXA7, MSX2 |
| negative regulation of keratinocyte migration | biological process | EPPK1 |
| negative regulation of keratinocyte proliferation | biological process | VDR, KLF9, INTU, SFN, EPPK1, KDF1, CASK, EFNB2, CD109 |
| negative regulation of kidney smooth muscle cell differentiation | biological process | SHH |
| negative regulation of kinase activity | biological process | HNRNPU, NPRL2, AJUBA, SOCS1, IRS2, PRDX3, CDKN1B, MSTN, CDKN1C, CSK, RHOH, AHSG |
| negative regulation of Kit signaling pathway | biological process | SH2B3 |
| negative regulation of L-glutamate import across plasma membrane | biological process | ARL6IP5 |
| negative regulation of lamellipodium assembly | biological process | PLXNB3, HRG, SLIT2 |
| negative regulation of lamellipodium morphogenesis | biological process | KANK1 |
| negative regulation of late endosome to lysosome transport | biological process | LRRK2, VPS35 |
| negative regulation of lens fiber cell differentiation | biological process | SPRY1, SPRED1, SPRY2, FOXE3 |
| negative regulation of leucine-tRNA ligase activity | biological process | RGN |
| negative regulation of leukocyte activation | biological process | GPER1 |
| negative regulation of leukocyte adhesion to arterial endothelial cell | biological process | KLF4 |
| negative regulation of leukocyte apoptotic process | biological process | HCLS1, MERTK |
| negative regulation of leukocyte cell-cell adhesion | biological process | ASS1, WNK1, ADTRP, MIA3, PPARA |
| negative regulation of leukocyte chemotaxis | biological process | SLIT2, GREM1 |
| negative regulation of leukocyte migration | biological process | HMOX1, IL33, ADTRP, HOXA7, ADA |
| negative regulation of leukocyte proliferation | biological process | GSTP1, CCL8 |
| negative regulation of leukocyte tethering or rolling | biological process | CCL28, CXCL12, CCL21 |
| negative regulation of lipase activity | biological process | POR, APOA1 |
| negative regulation of lipid binding | biological process | PEX19 |
| negative regulation of lipid biosynthetic process | biological process | APOE, CCDC3, CEACAM1, SERPINA12, ASXL3, GPER1 |
| negative regulation of lipid catabolic process | biological process | TNF, IL1B, BSCL2, CIDEA, CRTC3, ADRA2A, PDE3B, APOC1, HCAR2, FMC1, ACACB, INS, APOC3 |
| negative regulation of lipid kinase activity | biological process | PPP2R5A |
| negative regulation of lipid metabolic process | biological process | IL1B, CCDC3, APOC1, APOC3 |
| negative regulation of lipid storage | biological process | TNF, IL6, CRP, LEP, ITGAV, ASXL1, PTPN2, ABCG1, NFKBIA, ITGB3 |
| negative regulation of lipid transport | biological process | ITGAV, NR1H3, ITGB3, NR1H2 |
| negative regulation of lipid transport across blood brain barrier | biological process | APOE |
| negative regulation of lipopolysaccharide-mediated signaling pathway | biological process | LTF, TRIB1, DEFB114, CARD16, LILRA2, CARD8, SIGIRR, CACTIN |
| negative regulation of lipoprotein lipase activity | biological process | HDAC9, ANGPTL3, APOC1, SORT1, ANGPTL4, APOC3 |
| negative regulation of lipoprotein lipid oxidation | biological process | APOD |
| negative regulation of lipoprotein metabolic process | biological process | ITGAV, ITGB3 |
| negative regulation of locomotion | biological process | GHRL, ADORA2A |
| negative regulation of locomotion involved in locomotory behavior | biological process | GHSR, ARRDC3 |
| negative regulation of long term synaptic depression | biological process | FMR1, AGER |
| negative regulation of long-term synaptic potentiation | biological process | PRNP, PTN, TYROBP, ABL1, CX3CR1, EPHA4, PPP1R9A, FAM107A, AGER |
| negative regulation of low-density lipoprotein particle clearance | biological process | MYLIP, CSK, PCSK9, APOC3, KHSRP |
| negative regulation of low-density lipoprotein particle receptor binding | biological process | PCSK9 |
| negative regulation of low-density lipoprotein particle receptor biosynthetic process | biological process | ITGAV, ADIPOQ, ITGB3 |
| negative regulation of low-density lipoprotein particle receptor catabolic process | biological process | ANXA2, FURIN |
| negative regulation of lung blood pressure | biological process | SMAD3 |
| negative regulation of lung ciliated cell differentiation | biological process | IL13 |
| negative regulation of luteinizing hormone secretion | biological process | CRH, TACR2 |
| negative regulation of lyase activity | biological process | PHPT1 |
| negative regulation of lymphangiogenesis | biological process | EPHA2, FOXC1, VASH1 |
| negative regulation of lymphocyte activation | biological process | AXL, MERTK, TYRO3 |
| negative regulation of lymphocyte chemotaxis | biological process | PADI2 |
| negative regulation of lymphocyte differentiation | biological process | FBXO7 |
| negative regulation of lymphocyte migration | biological process | WASL, GCSAM, ADTRP, MIA3 |
| negative regulation of lymphocyte proliferation | biological process | IL2RA, IL2, SOX11, LST1, GAL |
| negative regulation of lysosomal protein catabolic process | biological process | LAPTM4B, ATP13A2, MGAT3, VPS35 |
| negative regulation of macroautophagy | biological process | MTOR, TSC1, QSOX1, PINK1, USP36, NPC1, SMCR8, LZTS1, LRRK2, NRBP2 |
| negative regulation of macroautophagy by TORC1 signaling | biological process | CLEC16A |
| negative regulation of macrophage activation | biological process | IL4, NR1H3, LRFN5, ZC3H12A, FCGR2B, VSIG4, BPI, IL31RA, ADGRF5 |
| negative regulation of macrophage antigen processing and presentation | biological process | FGL2 |
| negative regulation of macrophage apoptotic process | biological process | CCL5, SELENOS, GHSR, NOD2, IRF7 |
| negative regulation of macrophage chemotaxis | biological process | CYP19A1, SLAMF8, STAP1, C5, MMP28 |
| negative regulation of macrophage colony-stimulating factor signaling pathway | biological process | STAP1, PTPN2 |
| negative regulation of macrophage cytokine production | biological process | TGFB1, TGFB3, IRAK3, TGFB2 |
| negative regulation of macrophage derived foam cell differentiation | biological process | CRP, ITGAV, PPARG, NR1H3, ADIPOQ, ABCG1, ABCA5, NFKBIA, ITGB3, CETP, PPARA, NR1H2 |
| negative regulation of macrophage differentiation | biological process | INHBA, INHA, PTPN2, ADIPOQ, C1QC, GATA2, ZBTB46 |
| negative regulation of macrophage inflammatory protein 1 alpha production | biological process | MEFV |
| negative regulation of macrophage migration | biological process | CD200R1, EMILIN1 |
| negative regulation of macropinocytosis | biological process | STX1B |
| negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric | biological process | NAA10 |
| negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric | biological process | ATRX, TNKS |
| negative regulation of male germ cell proliferation | biological process | PRDX4, PTGDS, PTGDR2, HPGDS |
| negative regulation of male gonad development | biological process | WNT4 |
| negative regulation of mammary gland epithelial cell proliferation | biological process | BRCA2, GATA3, PHB2, ROBO1 |
| negative regulation of MAP kinase activity | biological process | IL1B, APOE, GSK3B, GSTP1, BMP7, BMP4, GBA, PTPRJ, SH2B3, DAB2IP, NUP62, STK38, SPRY1, CDK5RAP3, SMPD1, PTPN6, ADIPOQ, HMGCR, IRAK3, CAV3, DEFB114, RGS2, PAQR3, INPP5K, LYN, PRKCD, PTPN1, SORL1, DUSP1, HYAL2, SPRY2, DUSP7, RGS14, DUSP9, CBLC, AGT, NF1, SPRY3, UCHL1, CAV1 |
| negative regulation of MAPK cascade | biological process | GSTP1, NF2, RNF149, PPEF2, PSMD10, EFNA1, PEBP1, SPRED1, LEMD2, PTPN6, CAV3, ASH1L, DUSP1, P2RX7, DUSP3, DAG1, PIK3R2, DUSP16, PRDM15, NF1, CAV1 |
| negative regulation of mast cell activation | biological process | CNR1, CD300LF, CD84 |
| negative regulation of mast cell activation involved in immune response | biological process | ENPP3, FER |
| negative regulation of mast cell apoptotic process | biological process | KITLG, FCER1G |
| negative regulation of mast cell cytokine production | biological process | HMOX1, BCL6 |
| negative regulation of mast cell degranulation | biological process | HMOX1, IL13RA2, LGALS9, FOXF1, CD84 |
| negative regulation of mast cell differentiation | biological process | ZFPM1 |
| negative regulation of mast cell proliferation | biological process | ENPP3, LYN |
| negative regulation of matrix metallopeptidase secretion | biological process | IDH2 |
| negative regulation of mature B cell apoptotic process | biological process | MIF, CD74, BCL10, ADA |
| negative regulation of MDA-5 signaling pathway | biological process | C1QBP, TKFC, DHX58, RIOK3 |
| negative regulation of megakaryocyte differentiation | biological process | CIB1, HIST1H4A, PF4, PRMT1, GABPA, H4-16 |
| negative regulation of meiotic cell cycle | biological process | PRKACB, DUSP1, NPPC, NPR2 |
| negative regulation of meiotic cell cycle phase transition | biological process | OVOL1 |
| negative regulation of meiotic nuclear division | biological process | LIF, DMRT1, NANOS2, FBXO43 |
| negative regulation of melanin biosynthetic process | biological process | RAPGEF2, SLC24A5, MFSD12 |
| negative regulation of membrane depolarization during cardiac muscle cell action potential | biological process | CAV3 |
| negative regulation of membrane hyperpolarization | biological process | CRTC1 |
| negative regulation of membrane permeability | biological process | RASIP1 |
| negative regulation of membrane potential | biological process | PTN, BNIP3 |
| negative regulation of membrane protein ectodomain proteolysis | biological process | TIMP1, IL10, TIMP2, TIMP3, ROCK1, TIMP4, LRIG2, PTPN3 |
| negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential | biological process | KCNE3 |
| negative regulation of membrane tubulation | biological process | WASL |
| negative regulation of memory T cell differentiation | biological process | IFNL1, FGL2 |
| negative regulation of mesenchymal cell apoptotic process | biological process | SOX9, HIF1A, SHH, POU3F4, GDF5 |
| negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis | biological process | HNF1B |
| negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis | biological process | PAX8 |
| negative regulation of mesenchymal cell apoptotic process involved in metanephros development | biological process | HNF1B, PAX8 |
| negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis | biological process | BMP7 |
| negative regulation of mesenchymal cell proliferation | biological process | CTNNBIP1, PTN, WNT11, PHF14 |
| negative regulation of mesenchymal cell proliferation involved in lung development | biological process | NFIB, PHF14 |
| negative regulation of mesenchymal cell proliferation involved in ureter development | biological process | BMP4 |
| negative regulation of mesenchymal stem cell differentiation | biological process | REST |
| negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological process | STAT1, CTNNB1, CITED1 |
| negative regulation of mesoderm development | biological process | TP63, CER1 |
| negative regulation of mesodermal cell fate specification | biological process | DKK1, SFRP2, MESP1 |
| negative regulation of metabolic process | biological process | LEP |
| negative regulation of metalloendopeptidase activity | biological process | TIMP3, RECK |
| negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process | biological process | PICALM, SORL1 |
| negative regulation of metallopeptidase activity | biological process | LRP1 |
| negative regulation of metanephric comma-shaped body morphogenesis | biological process | BMP4 |
| negative regulation of metanephric glomerular mesangial cell proliferation | biological process | WT1 |
| negative regulation of metanephric mesenchymal cell migration | biological process | ADIPOQ |
| negative regulation of metanephric nephron tubule epithelial cell differentiation | biological process | STAT1 |
| negative regulation of metanephric S-shaped body morphogenesis | biological process | BMP4 |
| negative regulation of metaphase/anaphase transition of meiotic cell cycle | biological process | MOS |
| negative regulation of MHC class I biosynthetic process | biological process | TAF7 |
| negative regulation of MHC class II biosynthetic process | biological process | IL10, SPI1, NFX1, HDAC2, TAF7, PF4 |
| negative regulation of microglial cell activation | biological process | LDLR, PTPRC, NR1D1, GRN, CST7, TAFA3 |
| negative regulation of microglial cell migration | biological process | STAP1 |
| negative regulation of microtubule binding | biological process | TTBK2, MAP2 |
| negative regulation of microtubule depolymerization | biological process | CIB1, KATNB1, CAMSAP1, CAMSAP2, MID1IP1, MAP6D1, TPX2, TTBK2, CKAP2, APC, GAS2L1, ARHGEF2, TAOK1, BMERB1, HDGFL3, HDAC6, MID1, CLASP2, NAV3, GAS2L2, TRIM54, SPEF1, APC2, ATXN7, CLASP1, CAMSAP3, MAP1B |
| negative regulation of microtubule motor activity | biological process | MAP2 |
| negative regulation of microtubule polymerization | biological process | FKBP4, DYRK1A, SNCA, STMN1, MAP2, EML2, TUBB4A, MAPRE1, TBCD, CDH5, CLIP3 |
| negative regulation of microtubule polymerization or depolymerization | biological process | FKBP4, CLASP1 |
| negative regulation of microvillus assembly | biological process | RAP1GAP |
| negative regulation of miRNA catabolic process | biological process | TENT2 |
| negative regulation of mitochondrial calcium ion concentration | biological process | MICU2, LETM1 |
| negative regulation of mitochondrial depolarization | biological process | BCL2, SRC, FZD9, IFI6, GOT1, BOK |
| negative regulation of mitochondrial DNA metabolic process | biological process | FLCN |
| negative regulation of mitochondrial DNA replication | biological process | LIG3 |
| negative regulation of mitochondrial electron transport, NADH to ubiquinone | biological process | SNCA, DNAJC15 |
| negative regulation of mitochondrial fission | biological process | PPARGC1A, PINK1, MFI |
| negative regulation of mitochondrial fusion | biological process | HUWE1, OMA1, PRKN, TFRC, BNIP3, VAT1, ADCK1, MUL1 |
| negative regulation of mitochondrial membrane permeability | biological process | HK2 |
| negative regulation of mitochondrial membrane permeability involved in apoptotic process | biological process | ACAA2, BNIP3 |
| negative regulation of mitochondrial membrane potential | biological process | ARL6IP5, PRELID1, BNIP3L, HEBP2, BNIP3, RNF122, TRPV1 |
| negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | HSPA1A, FZD9, GCLC, ACAA2, SLC25A5, TMEM14A, BOK, MPV17L, SLC35F6 |
| negative regulation of mitochondrial RNA catabolic process | biological process | LRPPRC |
| negative regulation of mitochondrial translation | biological process | MALSU1 |
| negative regulation of mitochondrion organization | biological process | IAPP, FNIP2, FNIP1, FLCN |
| negative regulation of mitophagy | biological process | RNF41, USP30, TIGAR, TSC2, CLEC16A, TP53 |
| negative regulation of mitophagy in response to mitochondrial depolarization | biological process | HTRA2 |
| negative regulation of mitotic cell cycle | biological process | TGFB1, BCL2, RB1, TIMP2, BTG1, BTG3, NKX3-1, BTG4, SLC9A3R1, BRINP2, GAS1, ANGEL2, HECA, SCRIB, RFPL1, BTG2, DGKZ, MAD2L1, DLG1, CDKN1B, ABL1, PML, NLE1, CDKN1C, FOXC1, BRINP1, TRIM35, PTPN3, SMAD3, TNF, TP53 |
| negative regulation of mitotic cell cycle DNA replication | biological process | BCL6 |
| negative regulation of mitotic cell cycle phase transition | biological process | ZFP36L2, ZFP36L1, RGCC, TPRA1 |
| negative regulation of mitotic cell cycle, embryonic | biological process | CTNNB1, FZD3 |
| negative regulation of mitotic centrosome separation | biological process | KIF25 |
| negative regulation of mitotic DNA damage checkpoint | biological process | PPP1R10 |
| negative regulation of mitotic metaphase/anaphase transition | biological process | RAD21 |
| negative regulation of mitotic nuclear division | biological process | BMP7, BMP4, AURKAIP1, TOM1L1, NME6, MTBP, TOM1L2 |
| negative regulation of mitotic recombination | biological process | MLH1, ZSCAN4 |
| negative regulation of mitotic sister chromatid separation | biological process | PTTG2 |
| negative regulation of molecular function | biological process | TWIST1 |
| negative regulation of monocyte activation | biological process | CD33 |
| negative regulation of monocyte chemotactic protein-1 production | biological process | GSTP1, ERBIN, SOCS5, C1QTNF3, APOD, NR1H4 |
| negative regulation of monocyte chemotaxis | biological process | SLAMF8, DUSP1, CCN3, NBL1, SLIT2, GREM1 |
| negative regulation of monocyte differentiation | biological process | MYC, CDK6, HOXA7, ZBTB46, APCS, GPR68, INPP5D |
| negative regulation of mononuclear cell migration | biological process | BMP5, SLIT2 |
| negative regulation of monooxygenase activity | biological process | SNCA |
| negative regulation of motor neuron apoptotic process | biological process | MAP2K4, MAP3K12, ZPR1, CRLF1 |
| negative regulation of mRNA 3'-end processing | biological process | BARD1 |
| negative regulation of mRNA catabolic process | biological process | PKP3 |
| negative regulation of mRNA polyadenylation | biological process | CDK9, RNF20, ZC3H14, CCNT1, SUPT5H, NELFE, CTR9, RNF40 |
| negative regulation of mRNA splicing, via spliceosome | biological process | C1QBP, SRSF4, SRSF9, SRSF6, RBMX, PCBP4, DYRK1A, SRSF12, RBM10, SAP18, HNRNPA2B1, ACIN1, CELF4, SRSF7, SFSWAP, PTBP3, U2AF2, HNRNPK, RBM42 |
| negative regulation of mucus secretion | biological process | ADA |
| negative regulation of multicellular organism growth | biological process | GNAS, FXN, BBS2, SOCS2, PLAC8, LGMN, ADRB2, STC2, RAI1, ADRB1, PTCH1 |
| negative regulation of muscle atrophy | biological process | MTOR |
| negative regulation of muscle cell apoptotic process | biological process | HMOX1, ZC3H12A, PTK2B |
| negative regulation of muscle cell differentiation | biological process | ID2 |
| negative regulation of muscle contraction | biological process | TNNT1 |
| negative regulation of muscle hyperplasia | biological process | NOS3, KLF4 |
| negative regulation of muscle hypertrophy | biological process | MSTN |
| negative regulation of muscle organ development | biological process | IL6, SFMBT1 |
| negative regulation of muscle tissue development | biological process | FLCN, IGFBP5 |
| negative regulation of MyD88-dependent toll-like receptor signaling pathway | biological process | CD300LF |
| negative regulation of MyD88-independent toll-like receptor signaling pathway | biological process | TLR4, LY96, SARM1, TICAM2, TLR3, TICAM1 |
| negative regulation of myelination | biological process | IFNG, PTEN, CTSC, KLK8, TNFRSF21, JAM2, EIF2AK3 |
| negative regulation of myeloid cell apoptotic process | biological process | BCL2, MIF, MAEA, CLEC5A, EPO, APOH |
| negative regulation of myeloid cell differentiation | biological process | RBM15, WDR61, GPR171, HMGB3, PAF1, ITPKB, CTR9, NFKBIA, CDC73, CDK6, GATA2, MEIS1, MEIS2, LEO1, DLL1, HOXB8, ZBTB16, HOXA9, PTK2B |
| negative regulation of myeloid dendritic cell activation | biological process | IL10, HAVCR2, TSPAN32 |
| negative regulation of myeloid leukocyte differentiation | biological process | LYN, NME2, NME1 |
| negative regulation of myeloid progenitor cell differentiation | biological process | DPF2 |
| negative regulation of myoblast differentiation | biological process | TGFB1, TNF, SOX9, IL18, BMP4, DDIT3, PPARD, ANKRD2, NOTCH1, ID3, ZFHX3, MBNL3, EID2B, SRA1, SOSTDC1, CSRP3, TBX3, MSTN, GDF3, DLL1, CXCL14, NMRK2, CCL17, CXCL10 |
| negative regulation of myoblast fusion | biological process | CFLAR, CXCL10 |
| negative regulation of myoblast proliferation | biological process | MSTN, MYOD1 |
| negative regulation of myofibroblast differentiation | biological process | TP53INP1, PDCD4 |
| negative regulation of myosin-light-chain-phosphatase activity | biological process | TNF, ROCK2, ROCK1, IKBKB, NCKAP1L |
| negative regulation of myotube differentiation | biological process | HDAC4, XBP1, ANKRD2, NOTCH1, PLPP7, BHLHA15, MYOCD, HDAC3, CCN3, NKX2-5, HDAC5, TRIM72, BHLHE41 |
| negative regulation of N-terminal protein palmitoylation | biological process | HHATL |
| negative regulation of NAD(P)H oxidase activity | biological process | IL13, INS |
| negative regulation of natural killer cell activation | biological process | HAVCR2, PIBF1, FGR, CLNK |
| negative regulation of natural killer cell chemotaxis | biological process | CCL2 |
| negative regulation of natural killer cell cytokine production | biological process | CD96, HLA-F |
| negative regulation of natural killer cell degranulation | biological process | HLA-F |
| negative regulation of natural killer cell differentiation involved in immune response | biological process | PGLYRP2 |
| negative regulation of natural killer cell mediated cytotoxicity | biological process | IGF2, LGALS9, CRK, ARRB2, HLA-F |
| negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological process | HAVCR2, CEACAM1 |
| negative regulation of necroptotic process | biological process | SLC25A4, YBX3, FZD9, PELI1, FADD, CFLAR, BIRC2, ARHGEF2, RBCK1, BOK, CAV1 |
| negative regulation of necrotic cell death | biological process | UCN, MT3 |
| negative regulation of negative chemotaxis | biological process | ROBO2, ROBO1 |
| negative regulation of nervous system development | biological process | ELAPOR2 |
| negative regulation of netrin-activated signaling pathway | biological process | SIAH1, SIAH2, NTN1, DCC |
| negative regulation of neural crest formation | biological process | FUZ |
| negative regulation of neural precursor cell proliferation | biological process | IL1B, SPINT2, SPINT1, BTG2, RAPGEF1, GATA2, APPL2, ILK, LIMS2 |
| negative regulation of neuroblast proliferation | biological process | TGFB1, PTN, CTNNA1, NF1, TP53 |
| negative regulation of neurofibrillary tangle assembly | biological process | SORL1 |
| negative regulation of neurogenesis | biological process | IL1B, BMP7, DYNLT1, PCM1, TRIM11, BMPR1A, CCL11, HOOK3, NOTCH1, WNT3A, REST, ARHGEF2, SORL1, APPL2, CTDSP1, PITX3, MT3, BRINP1, WNT7A, LHX2, DLL3, TNF |
| negative regulation of neuroinflammatory response | biological process | NR1D1, CD200R1 |
| negative regulation of neuromuscular junction development | biological process | PTN |
| negative regulation of neuron apoptotic process | biological process | SOD1, APOE, BCL2, TGFB3, BDNF, LIG4, BAX, HIF1A, SOD2, HMOX1, AXL, PARK7, PIK3CA, NGF, F2R, PRDX2, FGF8, WFS1, NTRK1, GDNF, MSH2, XRCC2, RASA1, NMNAT1, JAK2, ISL1, FZD9, PPT1, SNX6, GRIN1, PIN1, STAR, KRAS, GCLC, KIF14, RETREG1, PRKN, OXR1, LGMN, PPARGC1A, NTF4, ADNP, CNTFR, AARS1, CITED1, PLA2G3, MDK, GABRB3, MEF2C, NAIP, NTRK2, SLC30A10, DRAXIN, GABRA5, ROCK1, CPEB4, NR4A2, PSEN1, BTG2, PINK1, GABRB2, ANGPT1, CHL1, MECP2, HIPK2, FGF20, AGAP2, DNAJC5, BOK, FAIM2, CRLF1, POU4F1, CLN3, NFATC4, SIX1, BHLHB9, ERBB3, MT3, GRN, EN1, BCL2L1, LRP1, ILK, FOXB1, SIX4, STAMBP, HRAS, VEGFB, VSTM2L, EN2, NTF3, PTPRZ1, CORO1A, SET, ALKBH1, NR4A3, NRP1, MAG, DLX1, ADAM8, PDPK1, PRKCG, ARRB2, UNC5B, ADORA2A, ITSN1, GRIK2, PTK2B, AMBRA1, CLCF1, CNTF, NES, NDNF, NEFL, CCL2, C5AR1, GDF5, TYRO3, FOXQ1, NRBP2 |
| negative regulation of neuron death | biological process | APOE, ESR1, IL6, ESR2, AKT1, CTNNB1, STAT3, PARK7, IGF1, CCL5, NTRK1, NMNAT1, BTBD10, TMEM259, SNCA, CHMP4A, HTRA2, PRKN, CD34, GPNMB, PPARGC1A, IL13, CHMP4B, ATP13A2, WNT3A, MDK, GABRB3, UCN, PINK1, GABRB2, REL, IKBKG, KIR3DL2, NENF, AP2B1, CBL, SORL1, PPP5C, CD200R1, CSF3, MT3, EN1, SULT1A3, PSMC1, CDK5, TIGAR, FGF21, FBXO7, SERPINF1, EPO, PPARA, TRAF2, HLA-F, LRRK2, VPS35 |
| negative regulation of neuron differentiation | biological process | IL1B, SOX3, APP, ITGB1, BMP7, SOX2, GLI3, CNTN4, LSM1, ISL1, MIB1, NKX2-2, HOXA2, PHOX2B, GPR37L1, HES1, CDK5RAP2, NEPRO, ASPM, EIF4ENIF1, FUOM, NOTCH1, REST, GDF11, CNTN2, DTX1, ASCL1, ZNF536, EIF4E, DDX6, PBX1, SIX3, SLC6A4, ID4, FOXG1, IRX3, CTDSP1, HES4, NOTCH3, MEIS1, ID2, LBX1, HEY1, DLL1, LMX1A, FOXO3, MAG, JAG1, DISP3, CALR, ZHX2, DIXDC1, HMG20A |
| negative regulation of neuron maturation | biological process | GSK3B, EDNRB, TBX6 |
| negative regulation of neuron migration | biological process | GSK3B, GNRH1, STAT3, NRG1, TNN, NRG3, COL3A1, SRGAP2, GPR173 |
| negative regulation of neuron projection development | biological process | FKBP4, GSK3B, KANK1, CIB1, VIM, B2M, BCL11A, CD38, RAB29, HDAC2, RTN4R, PMP22, DPYSL3, SNAPIN, TSC1, ITM2C, BAG5, WNT3A, PTPRG, DENND5A, RIT2, DKK1, STX1B, DCC, DGUOK, PTPN9, THOC2, MYLIP, ADCY6, PAQR3, EPHA4, SPOCK1, GAK, LPAR1, CBFA2T2, MT3, LRP1, PTPRO, EFNB2, CTSZ, LRIG2, PTPRS, NR2F1, RTN4RL2, TBX6, MAG, GFI1, ACP4, PRAG1, CRMP1, RAP1GAP2, ZNF365, RTN4RL1, LRRK2 |
| negative regulation of neuron projection regeneration | biological process | THY1 |
| negative regulation of neuron remodeling | biological process | BCL11A |
| negative regulation of neuronal action potential | biological process | GPR35 |
| negative regulation of neurotransmitter secretion | biological process | ASIC1, PNKD, SLC30A1, NF1 |
| negative regulation of neurotrophin TRK receptor signaling pathway | biological process | SPRY1, SPRY2, AGT |
| negative regulation of neutrophil activation | biological process | FCGR2B, GRN |
| negative regulation of neutrophil apoptotic process | biological process | ITPKB, CXCR2 |
| negative regulation of neutrophil chemotaxis | biological process | DPP4, C5AR2, SLIT2 |
| negative regulation of neutrophil degranulation | biological process | BCR, ABR |
| negative regulation of neutrophil differentiation | biological process | TRIB1, INPP5D |
| negative regulation of neutrophil migration | biological process | SLAMF8 |
| negative regulation of NF-kappaB import into nucleus | biological process | BMP7 |
| negative regulation of NF-kappaB transcription factor activity | biological process | CDKN2A, BMP7, CAT, CYP1B1, ANXA4, ERBIN, KLF4, DAP, FOXJ1, ITCH, ZC3H12A, PELI1, TRIM37, TMIGD3, IRAK1, DAB2IP, IRAK2, PSMD10, TRAF3, CDK5RAP3, SETD6, HAVCR2, PRMT2, OTULIN, IRAK3, TRIM40, TAX1BP1, RWDD3, NFKBIA, PYDC1, COMMD6, COMMD1, NLRP3, NR1H4, CYLD, AIM2, PTGIS, MTURN, USP7, RBCK1, ADORA3, CHP1, CARD8, NLRP12, TLR9, MAP2K5, TRAIP, PYCARD, SIVA1, TRIM21, LRRC14, PKHD1, TCEAL7, GFI1, CMKLR1, NLRP2, ARRB2, NWD1, PIAS4, BRMS1, PARP10, CACTIN, ZNF675 |
| negative regulation of NFAT protein import into nucleus | biological process | GSK3B, MTOR |
| negative regulation of NIK/NF-kappaB signaling | biological process | DDX3X, PPM1B, ZC3H12A, ADIPOR1, C1QTNF3, RELA, TSPAN6, TRIM40, RASSF2, NLRP3, CYLD, CPNE1, HDAC7, LITAF, PPM1A, CCN3, NLRP12, ADGRG3 |
| negative regulation of nitric oxide biosynthetic process | biological process | IL4, IL10, GLA, RGN, ZC3H12A, ROCK2, CD34, WDR35, PTGIS, KHSRP, CAV1 |
| negative regulation of nitric oxide mediated signal transduction | biological process | SPINK1, THBS1 |
| negative regulation of nitric-oxide synthase activity | biological process | GSK3B, GLA, CAV3, CNR1, NOSIP, ENG, CAV1 |
| negative regulation of nitric-oxide synthase biosynthetic process | biological process | GSTP1, SELENOS, PGGT1B, EDN1 |
| negative regulation of NK T cell proliferation | biological process | ZBTB7B |
| negative regulation of NLRP3 inflammasome complex assembly | biological process | MEFV, SIRT2, PYDC1, CPTP |
| negative regulation of NMDA glutamate receptor activity | biological process | EPHB2 |
| negative regulation of nodal signaling pathway | biological process | DAND5, DACT2 |
| negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological process | CER1, DAND5 |
| negative regulation of non-canonical Wnt signaling pathway | biological process | RNF213, IFT80, SFRP4, ZNRF3 |
| negative regulation of non-membrane spanning protein tyrosine kinase activity | biological process | DUSP22 |
| negative regulation of non-motile cilium assembly | biological process | MAP4 |
| negative regulation of norepinephrine secretion | biological process | PTGS1, GHSR, CRH, P2RY12, ADRA2A, ADRA2B, P2RY1, ADRA2C |
| negative regulation of norepinephrine uptake | biological process | SNCA |
| negative regulation of Notch signaling pathway | biological process | DLK1, BMP7, OVOL2, BCL6, FBXW7, NEURL1, NFKBIA, GDPD5, MMP14, RITA1, WWP2, TSPAN15, GATA2, NRARP, HEY2, YTHDF2, HIF1AN, NOTCH3, CBFA2T2, ARRDC1, EGFL7, HEY1, DLL1, SLC35C1, CHAC1, JAG2, ZBTB7A, DLX1, DLK2, JAG1, BEND6, NIBAN2, DLX2, DLL3 |
| negative regulation of Notch signaling pathway involved in somitogenesis | biological process | NRARP, LFNG |
| negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological process | PABPC1, NBAS, SECISBP2, DHX34 |
| negative regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | TOB1, TENT4B, TENT4A |
| negative regulation of nuclease activity | biological process | NEIL1 |
| negative regulation of nucleic acid-templated transcription | biological process | APEX1, RBBP8, NIF3L1, RCOR3, HIF3A, SIAH2, NPAT, RERE, RIOX2, SAP18, FEV, RUVBL2, HIRA, CCAR1, PARP14, SCAI, COPS2, SSX1, TDP2, WTIP, TOB1, CREG1, YAP1, CDYL2, HDAC3, SRSF2, CASP8AP2, ZMYND8, SF1, KCNIP3, TLE3, TOB2, PARP10, DDX54, BEND6, TLE6, TRIM22, CDY1 |
| negative regulation of nucleoside transport | biological process | RSC1A1 |
| negative regulation of nucleotide metabolic process | biological process | CDA |
| negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | ERBIN, PTPN22 |
| negative regulation of odontogenesis of dentin-containing tooth | biological process | TNFRSF11B, RSPO2 |
| negative regulation of oligodendrocyte apoptotic process | biological process | GAS6 |
| negative regulation of oligodendrocyte differentiation | biological process | CTNNB1, BMP4, HES1, NOTCH1, ID4, DRD3, ID2, DAAM2, DLX1, NF1, DLX2, DUSP10 |
| negative regulation of oligodendrocyte progenitor proliferation | biological process | SIRT2 |
| negative regulation of oocyte development | biological process | IGF1 |
| negative regulation of oocyte maturation | biological process | NPPC, NPR2 |
| negative regulation of organ growth | biological process | PTEN, STK3, FXN, STK4, PTK2, WWC1, SLC6A4, WWC3 |
| negative regulation of ossification | biological process | TGFB1, BCL2, SOX9, HIF1A, CHSY1, NOTCH1, MDK, MEF2C, KREMEN1, DKK1, SMAD6, TPH1, RBPJ, CALCA, LRP4, PTK2B, GFRA4 |
| negative regulation of osteoblast differentiation | biological process | TNF, FGFR1, AREG, HDAC4, NBR1, TNN, HOXA2, RIOX1, NOTCH1, SEMA4D, CITED1, FGF23, SKI, ID3, MEN1, SMAD6, CDK6, TWIST1, SUFU, TMEM64, HDAC7, TWSG1, VEGFC, TOB1, LRP5, ID2, RANBP3L, CHRD, LIMD1, AXIN2, OSTN, TRPM4, IGFBP5, PTCH1, SMAD3, GREM1, HAND2 |
| negative regulation of osteoblast proliferation | biological process | BCL2, TNN, NELL1, ATRAID, EIF2AK2, PLXNB1, SMAD3, GREM1 |
| negative regulation of osteoclast development | biological process | LTF, FBXW7, FBN1, CLDN18 |
| negative regulation of osteoclast differentiation | biological process | IL4, TLR4, CTNNB1, GPR137B, PIK3R1, FBN1, CCL3, TCTA, FSTL3, UBASH3B, LRRC17, CALCA, CARTPT, GPR55, TLR3, TMEM178A, LILRB4, PIAS3, TOB2, NF1, ZNF675, INPP5D |
| negative regulation of osteoclast proliferation | biological process | GREM1 |
| negative regulation of ovarian follicle development | biological process | AMH, HYAL3 |
| negative regulation of oxidative phosphorylation | biological process | PPIF, ACTN3 |
| negative regulation of oxidative phosphorylation uncoupler activity | biological process | PPIF, TWIST1 |
| negative regulation of oxidative stress-induced cell death | biological process | PARK7, PRKN, PINK1, PAGE4 |
| negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | SOD2, AKT1, NFE2L2, HSPB1, GPX1, NME8, NME5, HTRA2, BAG5, MAPK7, VNN1, NOL3, INS |
| negative regulation of oxidative stress-induced neuron death | biological process | PARK7, OXR1, TSC1, REST, ATF4, MEAK7, PINK1, NR4A3, FBXO7, FZD1, NCOA7 |
| negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological process | HIF1A, PARK7, PRKN, NONO |
| negative regulation of oxidoreductase activity | biological process | PRDX5, GZMA, HDAC6, MT3, HP, OXA1L, TMLHE, SLC4A1 |
| negative regulation of p38MAPK cascade | biological process | EZR, PTPN22, DLG1, CYLD, DUSP1, DUSP10 |
| negative regulation of pancreatic A cell differentiation | biological process | HES1 |
| negative regulation of pancreatic juice secretion | biological process | NR1H3, WNK3, WNK4 |
| negative regulation of pancreatic stellate cell proliferation | biological process | PPARG |
| negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | biological process | VPS13C |
| negative regulation of pathway-restricted SMAD protein phosphorylation | biological process | STRAP, XBP1, PMEPA1, DKK1, SMAD6, EMILIN1, ENG, LDLRAD4, SNX25, GREM1 |
| negative regulation of penile erection | biological process | ADA |
| negative regulation of pentose-phosphate shunt | biological process | TP53 |
| negative regulation of peptidase activity | biological process | SERPINC1, TIMP1, ANOS1, BIRC5, SERPINE1, TFPI2, SERPINA1, APP, A2M, SERPINA5, EPPIN, NGF, ECM1, SPINK1, SERPINA3, SLPI, TIMP2, XIAP, SERPINB7, TFPI, WFDC10A, SPINK5, ITIH2, SERPINB6, WFDC8, CSTB, CST2, PEBP1, SPINT2, TIMP3, SERPINB2, SERPINB9, COL7A1, PI16, WFDC13, BIRC7, CST11, WFDC1, SPINT1, CST5, APLP2, SERPINF2, SERPINB1, NAIP, SERPINA4, PI15, SPINK6, CSTA, CAST, SERPINB3, SPINT3, CARD18, BIRC6, PI3, CARD16, WFIKKN2, SERPINI1, WFDC2, TIMP4, R3HDML, SERPINB8, CST6, ITIH6, CD109, WFIKKN1, CST7, SERPING1, LXN, SERPINA10, CST4, COL6A3, GPC3, ITIH4, WFDC3, WFDC12, AMBP, UMODL1, ITIH5, SERPINA9, SERPINA12, A2ML1, COL28A1, WFDC5, HMSD, PAPLN, RECK, ITIH3, FETUB |
| negative regulation of peptide secretion | biological process | CD74 |
| negative regulation of peptidyl-cysteine S-nitrosylation | biological process | DMD, OXR1, SNTA1, NCOA7 |
| negative regulation of peptidyl-lysine acetylation | biological process | HDAC2, HINT2 |
| negative regulation of peptidyl-serine dephosphorylation | biological process | SWAP70, YWHAE, PPP1R16B |
| negative regulation of peptidyl-serine phosphorylation | biological process | BAX, BAK1, HGF, DMD, BDKRB2, NCK1, RACK1, INPP5F, NCK2, DKK1, RASSF2, PAQR3, GPD1L, INPP5K, PDE4D, CNKSR3, DMTN, CAV1 |
| negative regulation of peptidyl-serine phosphorylation of STAT protein | biological process | PWP1, GADD45A |
| negative regulation of peptidyl-threonine phosphorylation | biological process | PPEF2, SPRED1, SIRT2, PPP2R5D, PARD3, CALM1, CALM2, CALM3, INPP5K, SPRY2, DMTN, DGKQ |
| negative regulation of peptidyl-tyrosine autophosphorylation | biological process | CAV1 |
| negative regulation of peptidyl-tyrosine phosphorylation | biological process | SPINK1, ERRFI1, PTPN6, SEMA4D, PTPRC, SAMSN1, PRKCZ, PRKCD, SFRP2, DMTN, NTF3, LRRK1 |
| negative regulation of PERK-mediated unfolded protein response | biological process | NCK1, NCK2, PPP1R15A, PTPN1 |
| negative regulation of peroxisome proliferator activated receptor signaling pathway | biological process | ASXL1, TWIST1 |
| negative regulation of phagocytosis | biological process | TGFB1, PTEN, SNX3, RACK1, ADIPOQ, FCGR2B, ATG5, ATG3, DYSF, PRTN3, CSK, PIP4P2 |
| negative regulation of phosphatase activity | biological process | ELFN2, CNST, PPP1R36, ELL, PPP1R35, CSRNP3, CSRNP2, TMEM132D, SPRED1, RIMBP2, ZFYVE1, WNK1, CD2BP2, WDR81, TSKS, MPHOSPH10, URI1, FARP1, GPATCH2, TMEM225B, SLC7A14, SYTL2, SH3RF2, CHP1, RBM26, PPP1R26, DLG3, SFI1, PKMYT1, MARF1, RRP1B, ZCCHC9, CCDC8, PPP1R27, ELFN1, SPOCD1, CAMSAP3, MYO1D, DLG2, CEP192, ARFGEF3, PCIF1 |
| negative regulation of phosphatidylcholine biosynthetic process | biological process | LPCAT1 |
| negative regulation of phosphatidylcholine catabolic process | biological process | APOC1 |
| negative regulation of phosphatidylinositol 3-kinase activity | biological process | DAB2IP, RUBCN, PIK3IP1 |
| negative regulation of phosphatidylinositol 3-kinase signaling | biological process | PTEN, KLF4, DAB2IP, SLC9A3R1, CRYBA1, TWIST1, STAMBP, PIK3IP1, TSC2, INPP5E |
| negative regulation of phosphatidylinositol biosynthetic process | biological process | PDGFB, PDGFA |
| negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | biological process | BAG4 |
| negative regulation of phospholipase A2 activity | biological process | ANXA1, PLA2R1, ANXA8 |
| negative regulation of phospholipase activity | biological process | ANGPTL3, RGS2 |
| negative regulation of phospholipase C activity | biological process | BICD1, ABL1 |
| negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway | biological process | BICD1 |
| negative regulation of phospholipid biosynthetic process | biological process | SLC27A1, ABCA2 |
| negative regulation of phospholipid efflux | biological process | APOE |
| negative regulation of phosphoprotein phosphatase activity | biological process | RGN, PPP1R2, ELFN2, PPP1R14A, PPP1R36, PPP1R9B, PTN, PPP1R35, MASTL, PPP1R1B, PPP1R14C, PPME1, ARPP19, PPP1R8, PPP1R1A, PHACTR1, BOD1L2, TIPRL, URI1, BOD1, SAG, PPP4R4, FKBP1B, SH3RF2, PPP1R15A, PPP1R1C, FAM122A, BOD1L1, PPP1R26, PPP1R11, SET, PPP1R10, PPP1R27, PHACTR3, ELFN1, CRY2, CABIN1, PHACTR2, MYOZ1 |
| negative regulation of phosphorylation | biological process | INHBA, CDKN2A, BMP7, BMP4, INHA, DYNLL1, STAP1, CDKN2B, CDKN2D, ANKLE2, CDKN1B, CDKN2C, CDKN1A, CDKN1C |
| negative regulation of photoreceptor cell differentiation | biological process | SOX9, NOTCH1, DLX1, CNTF, DLX2 |
| negative regulation of pinocytosis | biological process | NR1H3, PROM2, NR1H2, CAV1 |
| negative regulation of planar cell polarity pathway involved in axis elongation | biological process | SFRP2 |
| negative regulation of plasma lipoprotein particle oxidation | biological process | PON1, APOM |
| negative regulation of plasma membrane long-chain fatty acid transport | biological process | AKT1, THBS1, IRS2, AKT2 |
| negative regulation of plasmacytoid dendritic cell cytokine production | biological process | BST2 |
| negative regulation of plasminogen activation | biological process | SERPINE1, THBS1, SERPINF2, CTSZ |
| negative regulation of platelet activation | biological process | APOE, NOS3, PDGFB, THBD, PDGFA, C1QTNF1, PDGFRA, F2 |
| negative regulation of platelet aggregation | biological process | SH2B3, FGG, ADAMTS18, PRKG1, C1QTNF1, PRKCD, ABAT, UBASH3B, CEACAM1 |
| negative regulation of platelet-derived growth factor receptor signaling pathway | biological process | PTPRJ, SNCA, SLC9A3R1, NDRG4, HGS, ADIPOQ, APOD, PTGIR |
| negative regulation of platelet-derived growth factor receptor-alpha signaling pathway | biological process | ADIPOQ, PHF14 |
| negative regulation of platelet-derived growth factor receptor-beta signaling pathway | biological process | PTPN2, MYOCD, LRP1, PTPN12 |
| negative regulation of podosome assembly | biological process | ARHGEF2 |
| negative regulation of polyamine transmembrane transport | biological process | OAZ3, OAZ1, OAZ2 |
| negative regulation of polynucleotide adenylyltransferase activity | biological process | ZFP36 |
| negative regulation of positive chemotaxis | biological process | ANGPT2 |
| negative regulation of positive thymic T cell selection | biological process | PTPN2 |
| negative regulation of post-translational protein modification | biological process | FLCN, P3H1 |
| negative regulation of postsynaptic membrane organization | biological process | APOE |
| negative regulation of potassium ion export across plasma membrane | biological process | KCNH2, KCNE3 |
| negative regulation of potassium ion transmembrane transport | biological process | CAB39, KCNH2, CAV3, NEDD4L, OXSR1, KEL, BIN1, RGS4, CAV1 |
| negative regulation of potassium ion transmembrane transporter activity | biological process | CAB39, CASQ2, ACTN2, CAV3, NEDD4L, OXSR1 |
| negative regulation of potassium ion transport | biological process | NOS3, CASQ2, ATF4, ACTN2, HCRT, PTK2B |
| negative regulation of presynapse assembly | biological process | DKK1 |
| negative regulation of presynaptic membrane organization | biological process | APOE |
| negative regulation of pri-miRNA transcription by RNA polymerase II | biological process | HDAC4, PDGFB, PPARD, NFIB, NFATC3, RELA, YY1, NFATC4, SRF, LILRB4, PPARA |
| negative regulation of primary amine oxidase activity | biological process | PRKN, AOC3 |
| negative regulation of pro-B cell differentiation | biological process | HES1, NOTCH1 |
| negative regulation of production of miRNAs involved in gene silencing by miRNA | biological process | TGFB1, ESR1, ZC3H12A, ZMPSTE24, ZC3H10, PPP3CA, NCOR2, NCOR1, TNF, TP53 |
| negative regulation of production of siRNA involved in RNA interference | biological process | TERT |
| negative regulation of programmed cell death | biological process | ALB, KIT, WFS1, NUP62, PSMC5, KANK2, TM7SF3, POU4F1, MECOM, AMIGO2, TIGAR, DCPS, PLCG2 |
| negative regulation of programmed necrotic cell death | biological process | NUPR1 |
| negative regulation of prolactin secretion | biological process | ANXA5 |
| negative regulation of prostaglandin biosynthetic process | biological process | PIBF1 |
| negative regulation of prostaglandin secretion | biological process | ATP5PF, ACSL4 |
| negative regulation of prostatic bud formation | biological process | BMP7, BMP4, SULF1 |
| negative regulation of proteasomal protein catabolic process | biological process | SCO1, MARCHF7, LAMP3, PSME3IP1, F8A1, ALAD, GABARAPL2, PSMF1, OPHN1, PRKCG |
| negative regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | BAG6, HFE, PARK7, SHH, WAC, MTM1, OGT, CAMLG, RPL11, TRIM39, TLK2, GIPC1, RYBP, BAG5, FHIT, CCAR2, SDCBP, SENP1, USP7, SMARCC1, KLHL40, UCHL5, DDRGK1, CLEC16A, N4BP1, UBXN1, TAF9 |
| negative regulation of protection from non-homologous end joining at telomere | biological process | ERCC4 |
| negative regulation of protein acetylation | biological process | PARK7, MAGEA2 |
| negative regulation of protein ADP-ribosylation | biological process | TINF2 |
| negative regulation of protein autophosphorylation | biological process | ERRFI1, ADIPOQ, ENPP1, PTPRC, CHP1, NLRP12, ENG, IMPACT, GFRA2, MVP |
| negative regulation of protein autoubiquitination | biological process | MARCHF7, TAF1 |
| negative regulation of protein binding | biological process | BAX, GSK3B, PARK7, MAPK8, SLPI, SENP2, GNL3L, CARM1, PIN1, CTNNBIP1, PDGFB, GTF2F1, CSNK1E, RACK1, CFHR1, DVL1, TMBIM6, PSME3IP1, DAB2, ADNP, DISC1, STUB1, TDG, IFIT1, FRMD7, EFHB, DKK1, ROCK1, DTNBP1, USP33, MITD1, EPB41L5, ITGB1BP1, RALB, PEX14, LRPAP1, CARD18, PRKCD, IFIT2, CARD16, SORL1, CDKN1A, NFATC4, DACT1, WFIKKN2, CTSZ, TLE5, WFIKKN1, DDX11, PIM2, DNAJB2, PPARA, GOLGA2, TMC8, TFIP11, CAMK1, SYMPK, AURKB, ZFPM1, NES, LRRK2, TTBK1, CFHR5, CAV1, XIRP1 |
| negative regulation of protein catabolic process | biological process | EGFR, PARK7, NOS2, NRG1, SHH, SNX3, PIN1, MDM4, HMGCR, RELA, SIRT2, IRAK3, TRIM40, AZIN1, MAD2L1, GRIN2C, MYCBP2, AZIN2, AGAP2, MAD2L2, SNX12, SF3B3, CYP51A1, BANP, RILP, ADGRB1, GRIN2A, DYSF, INS, PRKCG, SMAD3, FMN2 |
| negative regulation of protein complex assembly | biological process | GSK3B, RAF1, CDC42, IAPP, DDX3X, ISL1, CRBN, TRAF3IP1, CTNNBIP1, CRYAB, DNAJC15, PEX5, LAMP2, EIF4EBP1, AIDA, ULK1, EP300, LCMT1, RIOK3, OPRD1, PRKCZ, SVIP, SORL1, HDAC6, CLDN7, IMPACT, TMC8, TFIP11 |
| negative regulation of protein complex disassembly | biological process | TNF, SLN, IRAK3, HDAC6 |
| negative regulation of protein dephosphorylation | biological process | ARPP19, PPP1R8, YWHAE, PPP1R16B, PPP1R15A, YWHAB, MFHAS1, PPP1R11 |
| negative regulation of protein deubiquitination | biological process | TRIM21, DNAJB2 |
| negative regulation of protein exit from endoplasmic reticulum | biological process | INSIG1 |
| negative regulation of protein export from nucleus | biological process | PARK7, RANGAP1, SP100, BARD1, CDK5 |
| negative regulation of protein glutathionylation | biological process | G6PD, FXYD1 |
| negative regulation of protein glycosylation | biological process | MGAT4D |
| negative regulation of protein glycosylation in Golgi | biological process | TMEM59, ACER2 |
| negative regulation of protein homodimerization activity | biological process | HSPA5, ITGA4 |
| negative regulation of protein homooligomerization | biological process | CLU, SRC, BCL11A, VPS35 |
| negative regulation of protein import into nucleus | biological process | FERMT1, PKIG, APOD, RAB23, ANGPT1, PKIA, SUFU, MDFIC, UFM1, CHP1, CABP1, NF1, CD36 |
| negative regulation of protein import into nucleus, translocation | biological process | GAS6 |
| negative regulation of protein K48-linked deubiquitination | biological process | PARK7, UBXN1 |
| negative regulation of protein K48-linked ubiquitination | biological process | TRIM44 |
| negative regulation of protein K63-linked ubiquitination | biological process | GPS2, PLAA, PARP10 |
| negative regulation of protein kinase activity | biological process | IL6, DCN, AKT1, CDKN2A, CIB1, HSPB1, GSTP1, PARK7, RB1, FLRT3, NF2, LRRC4C, GADD45B, MLLT1, RTRAF, RGN, TRIB3, DUSP19, NCK1, SNCA, DVL1, PRKAG2, WARS1, CEP85, SPRED1, PPP1R1B, TARBP2, GSKIP, SOCS1, CEP43, TAF7, TRIB1, WNK1, CAV3, DTNBP1, TAOK3, PKIG, LRP6, PTPRC, GADD45A, PSEN1, PYDC1, ITGB1BP1, ITPRIP, PKIA, INPP5K, DUS2, SH3BP5, SFN, GNAQ, PKIB, DNAJC3, CHP1, SMCR8, UBASH3B, TESC, EPHA1, DEPTOR, DBNDD2, GMFB, YWHAG, ILK, CEACAM1, QARS1, TRIB2, PKN1, PPM1E, CAMK2N2, WWTR1, THY1, TSC2, GMFG, AKT1S1, DBNDD1, IMPACT, PDPK1, ADORA2A, NF1, SOCS3 |
| negative regulation of protein kinase activity by protein phosphorylation | biological process | AKT1 |
| negative regulation of protein kinase activity by regulation of protein phosphorylation | biological process | NPM1, ADARB1, ADAR, CORO1C, CDK5RAP3, DUSP26, DUSP10 |
| negative regulation of protein kinase B signaling | biological process | CIB1, PTEN, XDH, PTPRJ, KLF4, DDIT3, MTM1, BANK1, TRIB3, SH2B3, RACK1, SLC9A3R1, PPP2R5C, PHLPP2, PLEKHA1, LEMD2, RAPGEF1, PDCD6, CRYBA1, DLG1, THEM4, INPP5K, CAVIN3, FLCN, HYAL2, DRD3, EPHA2, MSTN, DAG1, SFRP5, MUL1, PKHD1, TSC2, PHLPP1, DRD2, ARRB2, OTUD3, MAGI2, PHLDA3, GPER1 |
| negative regulation of protein kinase C signaling | biological process | DGKG, GPD1L, MYADM, DGKD |
| negative regulation of protein lipidation | biological process | DBI |
| negative regulation of protein localization to cell cortex | biological process | SAPCD2 |
| negative regulation of protein localization to cell leading edge | biological process | RIPOR2 |
| negative regulation of protein localization to cell surface | biological process | ASTN2, LEPROTL1, GPM6B, PICALM, SNX33, ACTN2, CAV3, LEPROT, COMMD1, NEDD4L, ARF6, TAX1BP3 |
| negative regulation of protein localization to centrosome | biological process | NSFL1C, UBXN2B |
| negative regulation of protein localization to chromosome, telomeric region | biological process | MACROH2A1 |
| negative regulation of protein localization to ciliary membrane | biological process | LZTFL1 |
| negative regulation of protein localization to cilium | biological process | LZTFL1, INPP5E |
| negative regulation of protein localization to endosome | biological process | ANKRD13A |
| negative regulation of protein localization to lysosome | biological process | ROCK2 |
| negative regulation of protein localization to microtubule | biological process | TTBK2, ABHD17B, ABHD17A |
| negative regulation of protein localization to nucleolus | biological process | POLR1A |
| negative regulation of protein localization to nucleus | biological process | GSK3B, SIN3A, MAGED1, FBXO4, CLDN18, TRIM40, ILRUN, DCLK1, FLCN, LZTS2, MFHAS1, TRIM29, OTUD7B, LILRB4, DCLK3 |
| negative regulation of protein localization to plasma membrane | biological process | TGFB1, PPFIA1, PPP2R5A, NUMB, DAB2, TMEM59, MRAP2, PICALM, PID1, AP2M1, RHOQ, GBP1, CLTC, TMBIM1, BCL2L1, RSC1A1 |
| negative regulation of protein metabolic process | biological process | LDLR |
| negative regulation of protein neddylation | biological process | RPL5, RPL11, COPS9 |
| negative regulation of protein phosphorylation | biological process | TGFB1, CCNB1, CIB1, MTOR, PTEN, PARK7, INSR, XDH, IL2, DUSP6, MAS1, PRNP, TERF2IP, DNAJC10, RGN, ZC3H12A, TRAF3IP1, C9orf72, DAB2IP, KIRREL1, SH3GL2, CORO1C, DVL1, EPHB2, PRKN, WARS1, CDK5RAP3, PPARGC1A, NNT, NIBAN1, FBLN1, PID1, MEN1, LRP6, PSEN1, PTPN13, ANGPT1, PRR5L, CTDSP2, PRKDC, INSM1, PAQR3, INPP5K, LYN, MYADM, CHP1, PARD6A, IBTK, CTDSPL, PPP5C, CTDSP1, ZBED3, FKBP8, PLPP3, PKN1, CD109, WWTR1, MICAL1, IMPACT, DRD2, ARRB2, CACTIN, SLIT2, CRKL, BDKRB1, LRRK2, KIRREL2 |
| negative regulation of protein polymerization | biological process | VDAC2 |
| negative regulation of protein polyubiquitination | biological process | DYSF |
| negative regulation of protein processing | biological process | MDM2, PRNP, TMEM59, GAS1, NLRP7, GLG1, SNX12, MAGEA3, CHAC1, ACP4, LRRK2 |
| negative regulation of protein processing involved in protein targeting to mitochondrion | biological process | SIRT4, LRRK2 |
| negative regulation of protein refolding | biological process | SNRNP70, ST13, PDCL, BAG5 |
| negative regulation of protein secretion | biological process | ANXA1, RHBDF1, HMGCR, RSAD2, SERGEF, ADTRP, DPH3, FRMD4A, DRD3, CYP51A1, INS, DRD2, RHBDF2, SRCIN1, DRD4 |
| negative regulation of protein serine/threonine kinase activity | biological process | CIB1, HSPB1, INKA2, DAB2IP, INKA1, CDK5RAP3, DTNBP1, LRP6, GADD45A, SLC8A3, MACROH2A1, ABL1, SFN, SLC8A1, LRP5, YWHAG, PYCARD, RPTOR |
| negative regulation of protein sumoylation | biological process | CTNNB1, PARK7, GNL3L, MAGEA2, CAPN3, RELA, HMG20B, FSCB, PIAS3, HMG20A |
| negative regulation of protein targeting to membrane | biological process | ITGB1BP1, INPP5K, KCNE1, DMTN, GDI1 |
| negative regulation of protein targeting to mitochondrion | biological process | BAG4, BAG3, LMAN1, SIAH3, MFI, LRRK2 |
| negative regulation of protein transport | biological process | SNX3, WWP2, NDFIP1, NDFIP2, SNX12 |
| negative regulation of protein tyrosine kinase activity | biological process | RACK1, PTPN2, CEP43, PTPRC, SH3BP5, IBTK, HYAL2, THY1, PTK6, MVP, SH3BP5L, SRCIN1, CAV1 |
| negative regulation of protein tyrosine phosphatase activity | biological process | GNAI2 |
| negative regulation of protein ubiquitination | biological process | MTOR, PARK7, HSPA1A, HSPA1B, GTPBP4, SENP2, GNL3L, OGT, CAMLG, VPS28, IVNS1ABP, RPS3, GCLC, RASD2, BAG5, HDAC8, PER2, ATG5, ISG15, SQSTM1, CRY1, SH3RF2, CHP1, SOX4, USP4, NXN, SVBP, PRKCE, SIRT7, ADGRB1, CDK5, KLHL40, U2AF2, PRKCG, ARRB2, PRR7, PRMT3, PINX1, N4BP1, UBXN1, CAV1 |
| negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological process | CDKN2A, HFE, RPL5, RPS7, QRICH2, SGTA, RPL11, TRIM39, PSEN1, TAF1, CSNK2A1, HIPK2, SUFU, PML, RPL23 |
| negative regulation of proteoglycan biosynthetic process | biological process | SLC2A10 |
| negative regulation of proteolysis | biological process | AKT1, BAG6, SERPINA5, PLAT, TIMP2, SPINK5, CSTB, DNAJC1, IDE, CLN8, CSTA, SERPINB3, CLN3, HDAC6, CDK5, CST4, F2, INS, TM4SF20, TP53, NR1H2 |
| negative regulation of proteolysis involved in cellular protein catabolic process | biological process | CDKN2A, EFNA1, EPHA4 |
| negative regulation of pyruvate dehydrogenase activity | biological process | PDK4, PDK3, PDK1, PDK2 |
| negative regulation of Rac protein signal transduction | biological process | ARHGAP24, STMN3, NF1, ARHGAP44 |
| negative regulation of Ras protein signal transduction | biological process | TIMP2, RASA1, DAB2IP, EPHB2, NUP62, RASA2, SPRY1, FBP1, LZTR1, RAPGEF1, MAPKAP1, TGFB2, MFN2, TNK1, SPRY2, STAMBP, RASA4, RASA3, TRIM67, RASAL3, RASAL1, NF1, SPRY3 |
| negative regulation of reactive oxygen species biosynthetic process | biological process | COA8, CTNS, SLC30A10, ABCD2, CFLAR, TRAP1, PAGE4, SLC18A2, INS, ABCD1 |
| negative regulation of reactive oxygen species metabolic process | biological process | BCL2, BRCA1, HIF1A, ESR2, MYCN, VDAC1, SIRT5, CRYAB, PRKN, BCR, SIRT2, ATG5, PINK1, TFAP2A, BNIP3, AATF, HK2, MT3, TIGAR, TP53 |
| negative regulation of receptor activity | biological process | HFE, PPARGC1A, LYPD6, GPIHBP1, LY6G6D, DKK1, LYNX1, LY6E, SPINT3, LRPAP1, WFIKKN2, DKK4, IL18BP, WFIKKN1, CNRIP1, LY6H, PCSK9, DKK2 |
| negative regulation of receptor binding | biological process | B2M, HFE, ANXA2, ATP2A2, PTPRF, ADIPOQ, CRTAC1, ATP2A3 |
| negative regulation of receptor biosynthetic process | biological process | PPARG, NR1D1, PPARA |
| negative regulation of receptor internalization | biological process | ANXA2, ANKRD13A, LRRTM1, SDCBP, LRPAP1, DLG4, ANKRD13B, WDR54, LRRTM2, ANKRD13D, ATXN2 |
| negative regulation of receptor localization to synapse | biological process | CNIH2 |
| negative regulation of receptor recycling | biological process | OPTN, AP1AR, PCSK9, TRAT1 |
| negative regulation of receptor signaling pathway via STAT | biological process | PTPRT |
| negative regulation of receptor-mediated endocytosis | biological process | PICALM, RAC1, APOC1, ARF6, APOC3 |
| negative regulation of receptor-mediated endocytosis involved in cholesterol transport | biological process | PCSK9, ABCA2 |
| negative regulation of reciprocal meiotic recombination | biological process | MSH2 |
| negative regulation of regulatory T cell differentiation | biological process | CTLA4, MDK, TNFSF4, IRF1 |
| negative regulation of relaxation of cardiac muscle | biological process | PDE4B, PDE4D |
| negative regulation of relaxation of muscle | biological process | NEUROG1, TIFAB |
| negative regulation of release of cytochrome c from mitochondria | biological process | AKT1, GPX1, IGF1, HGF, PARL, FXN, HIGD1A, PRELID1, PSMD10, PRKN, OPA1, TRIAP1, PPIF, BCL2L1, AVP, NOL3, ARRB2, PAM16 |
| negative regulation of release of sequestered calcium ion into cytosol | biological process | TGFB1, FKBP1B, NTSR1 |
| negative regulation of renal albumin absorption | biological process | GAS6 |
| negative regulation of renal sodium excretion | biological process | COMT, AVPR2 |
| negative regulation of renin secretion into blood stream | biological process | F2R |
| negative regulation of respiratory burst | biological process | BCR |
| negative regulation of respiratory burst involved in inflammatory response | biological process | RPS19, SLAMF8, GRN, INS, DUSP10 |
| negative regulation of response to cytokine stimulus | biological process | KLF4, SH2B3, APOA1, MAPK7, MAP2K5, TLE5 |
| negative regulation of response to endoplasmic reticulum stress | biological process | AQP11, ALOX5 |
| negative regulation of response to gamma radiation | biological process | PRKDC |
| negative regulation of response to oxidative stress | biological process | MCTP1, MACROH2A1, GGT7 |
| negative regulation of retinal cell programmed cell death | biological process | BCL2 |
| negative regulation of retinal ganglion cell axon guidance | biological process | PTPRO, SLIT2 |
| negative regulation of retinoic acid biosynthetic process | biological process | AKR1C3 |
| negative regulation of retinoic acid receptor signaling pathway | biological process | EZH2, CYP26B1, CNOT1, DHRS3, PRAME, CYP26A1, ZNF536, CYP26C1, CALR |
| negative regulation of retrograde protein transport, ER to cytosol | biological process | DERL2, UBAC2, YOD1, SVIP, ERLEC1, OS9, DERL3 |
| negative regulation of retrograde transport, endosome to Golgi | biological process | ARFIP1 |
| negative regulation of Rho guanyl-nucleotide exchange factor activity | biological process | RIPOR1, RIPOR2 |
| negative regulation of Rho protein signal transduction | biological process | KANK1, ITGB1, BCL6, TNFAIP1, KCTD13, DLC1, ARHGAP35, STMN1, SCAI, ADRA1A, ABL2, FLCN, KCTD10, CCDC125, ITGA3, ARHGAP42, RASIP1, RIPOR1, MYOC, RIPOR2 |
| negative regulation of Rho-dependent protein serine/threonine kinase activity | biological process | CHORDC1, RASIP1 |
| negative regulation of ribosomal DNA heterochromatin assembly | biological process | PHF2, PHF8 |
| negative regulation of ribosome biogenesis | biological process | PTEN, MALSU1 |
| negative regulation of RIG-I signaling pathway | biological process | C1QBP, NLRX1, SEC14L1, DHX58, UFD1, RNF125, NPLOC4 |
| negative regulation of ripoptosome assembly involved in necroptotic process | biological process | BIRC2 |
| negative regulation of RNA biosynthetic process | biological process | RGN, FCN3 |
| negative regulation of RNA catabolic process | biological process | NRDE2 |
| negative regulation of RNA export from nucleus | biological process | NUP153, TPR |
| negative regulation of RNA interference | biological process | ADAR |
| negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological process | DDIT3, FBXW7, TAF1, ZNF593 |
| negative regulation of RNA polymerase II transcription preinitiation complex assembly | biological process | HMGB1, THRA |
| negative regulation of RNA splicing | biological process | RPS13, TMBIM6, PTBP3 |
| negative regulation of RNA-directed 5'-3' RNA polymerase activity | biological process | EIF4A2 |
| negative regulation of rRNA processing | biological process | SHQ1, NUDT16, KAT2B |
| negative regulation of ruffle assembly | biological process | KANK1, STAP1, PFN2, ARHGAP24, EVL, TACSTD2 |
| negative regulation of ryanodine-sensitive calcium-release channel activity | biological process | SRI, TRDN, CASQ2, GSTO1, PKD2, CALM1, CALM2, CALM3, FKBP1B |
| negative regulation of saliva secretion | biological process | NEUROG1, TIFAB |
| negative regulation of sarcomere organization | biological process | CAV3 |
| negative regulation of satellite cell differentiation | biological process | AKIRIN1, EPHB1, SIX4, MSTN |
| negative regulation of Schwann cell proliferation | biological process | DICER1, RNF10, ASCL2, SKI |
| negative regulation of secretion | biological process | EGF, NRG1, ERBB3 |
| negative regulation of secretion by cell | biological process | VAMP8, VAMP3 |
| negative regulation of secretion of lysosomal enzymes | biological process | NR1H3 |
| negative regulation of selenocysteine incorporation | biological process | EIF4A3 |
| negative regulation of selenocysteine insertion sequence binding | biological process | EIF4A3 |
| negative regulation of sensory perception of pain | biological process | TAC4, CCN3 |
| negative regulation of sequence-specific DNA binding transcription factor activity | biological process | ESR1, HMOX1, NR0B1, GAS6, EZH2, RB1, SUMO1, WFS1, TCF7L2, PRNP, HDAC4, KLF4, DDIT3, CEBPG, KEAP1, PLA2G10, HDAC2, CTNNBIP1, BTRC, PIAS2, EOMES, IRAK2, HES1, NUPR1, HES6, BHLHE40, ID3, TRIB1, PHB2, TAF3, MED13, MEN1, FOXS1, TNFRSF4, RLIM, TAF1, SP100, PBX1, TWIST1, SUFU, WWP2, PEX14, MAD2L2, EGLN1, TNFSF4, MAP3K10, ID2, POU4F2, SFRP5, FZD6, SFRP4, TBX6, PROX1, PTCH1, SIGIRR, GLIS2, PAXIP1, FOXH1, RNF2, HAND2, FOXA2 |
| negative regulation of sequestering of triglyceride | biological process | PPARG, ABHD5, OSBPL8, PPARA |
| negative regulation of serine-type endopeptidase activity | biological process | SPINK1, SPINK5, SPINK6, ANXA8 |
| negative regulation of serine-type peptidase activity | biological process | SPINK5, SPINK6 |
| negative regulation of serotonin secretion | biological process | CNR1, HTR1B, HRH3 |
| negative regulation of serotonin uptake | biological process | SNCA, GPM6B |
| negative regulation of short-term synaptic potentiation | biological process | PRRT2 |
| negative regulation of signal transduction | biological process | GSK3B, CISH, SOCS2, BRAP, DDIT4L, RGS17, SOCS5, MPIG6B, SOCS4, RGS16, ACVR1, SEC14L1, RGS20, PMEPA1, SOCS1, SCAI, RGS11, SRMS, PYDC1, PRR5L, RGS2, RGS10, SNX13, RGS5, SOCS7, PTPN1, RGS6, RGS1, UBASH3B, PAK1IP1, SOCS6, ERBB3, NLRP12, RGS19, MFHAS1, RGS7, HHIP, RGS14, RGS18, ARRB2, PTK6, KIF26A, RGS12, RGS8, LDLRAD4, RGS9, INPP5D, SOCS3, RGS4, RGS9BP, RIPOR2, RGS13, CAV1 |
| negative regulation of signal transduction by p53 class mediator | biological process | MDM2, RNF34, ELL3 |
| negative regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | APOBEC3F, RESF1, TASOR, HMGA2, INPP5K, APOBEC3G, SETDB1, APOBEC3A, APOBEC3C, APOBEC3B, MORC2 |
| negative regulation of single-species biofilm formation in or on host organism | biological process | LTF, BPIFA1 |
| negative regulation of sister chromatid cohesion | biological process | ESPL1, WAPL |
| negative regulation of skeletal muscle acetylcholine-gated channel clustering | biological process | FZD9 |
| negative regulation of skeletal muscle cell differentiation | biological process | MYOCD, S100B |
| negative regulation of skeletal muscle hypertrophy | biological process | IGFBP5 |
| negative regulation of skeletal muscle satellite cell proliferation | biological process | AKIRIN1, EPHB1, MSTN, SIX5 |
| negative regulation of skeletal muscle tissue development | biological process | TGFB1, TSC22D3, YBX3, TWIST1 |
| negative regulation of skeletal muscle tissue growth | biological process | TLL2, MSTN |
| negative regulation of skeletal muscle tissue regeneration | biological process | MYOZ1 |
| negative regulation of SMAD protein complex assembly | biological process | PMEPA1, SMAD6, PPM1A, TBX20, LDLRAD4 |
| negative regulation of SMAD protein signal transduction | biological process | SLC2A10, FAM89B, VEPH1, CCN3, CILP |
| negative regulation of small GTPase mediated signal transduction | biological process | CGNL1, CD2AP, ARHGAP25, ARHGAP12, SH3BP1, SLIT2 |
| negative regulation of smooth muscle cell apoptotic process | biological process | GSK3B, IGF1, LRP6, DIPK2A, EDN1, ARRB2, APOH |
| negative regulation of smooth muscle cell chemotaxis | biological process | AIF1, CORO1B, SLIT2 |
| negative regulation of smooth muscle cell differentiation | biological process | EREG, ANKRD17, MECP2, PRDM6, MED28, FOXO4, RBPMS2 |
| negative regulation of smooth muscle cell migration | biological process | SERPINE1, APEX1, SEMA6D, PPARD, NDRG4, BMPR1A, PPARGC1A, TRIB1, LRP1, ILK, IGFBP5, SLIT2 |
| negative regulation of smooth muscle cell proliferation | biological process | IFNG, ESR1, IL12A, ESR2, NDRG2, HMOX1, COMT, PPARG, AIF1, KLF4, IL15, CTNNBIP1, PPARD, NDRG4, PPARGC1A, TRIB1, APOD, NPR3, MFN2, NPR1, ILK, PTGIR, SF1, ANG, IGFBP5, VIPR2, OGN |
| negative regulation of smooth muscle cell-matrix adhesion | biological process | SERPINE1, APOD |
| negative regulation of smooth muscle contraction | biological process | PTGS2, CALCRL, ADRB2, PRKG1, CALCA |
| negative regulation of smoothened signaling pathway | biological process | RB1, GLI3, TULP3, BTRC, GPR37L1, HERC4, MGRN1, PTCH2, ULK3, MEGF8, CD3E, SALL3, SUFU, RUNX2, IFT122, HHIP, GPC3, GLI2, PTCH1, KIF7, GLIS2, IFT172 |
| negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | TRAF3IP1, TULP3, PRKACB, SUFU, GPR161 |
| negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning | biological process | TULP3, IFT122 |
| negative regulation of SNARE complex assembly | biological process | PRRT2, ANKRD27, TRIM9 |
| negative regulation of sodium ion transmembrane transport | biological process | CAMK2D, COMMD1, NEDD4L |
| negative regulation of sodium ion transmembrane transporter activity | biological process | CAMK2D, HECW2, NEDD4, NEDD4L, HECW1, PRKCE, PCSK9, AGT |
| negative regulation of sodium ion transport | biological process | WNK3, WNK4, SLC9A3R1, WNK1, NEDD4, WNK2 |
| negative regulation of sodium-dependent phosphate transport | biological process | SFRP4 |
| negative regulation of sodium:proton antiporter activity | biological process | SLC9A3R1, DRD3 |
| negative regulation of sphingolipid biosynthetic process | biological process | ORMDL2, ABCA2 |
| negative regulation of spontaneous neurotransmitter secretion | biological process | PRKN, PPP1R9A |
| negative regulation of sprouting angiogenesis | biological process | ADAMTS9, THBS1, E2F2, ALOX5, SEMA6A, EPN1, KLF2, EPN2, SYNJ2BP |
| negative regulation of SREBP signaling pathway | biological process | FBXW7 |
| negative regulation of stem cell differentiation | biological process | HNRNPU, HES1, NOTCH1, H1-8, CDK13, ZFP36L2, LBH, YAP1, CDK12, NELFB, JAG1, ESRRB, TRIM6 |
| negative regulation of stem cell population maintenance | biological process | LOXL2, WNT9B, ZNF706 |
| negative regulation of stem cell proliferation | biological process | OVOL2, FERMT1, FBLN1, OVOL1, KDF1 |
| negative regulation of steroid biosynthetic process | biological process | WNT4, BMP5, INSIG1, BMP2, INSIG2 |
| negative regulation of steroid metabolic process | biological process | UGT1A8 |
| negative regulation of stomach neuroendocrine cell differentiation | biological process | HES1 |
| negative regulation of stress fiber assembly | biological process | PPFIA1, TJP1, ARAP1, DLC1, STMN1, S1PR1, FRMD7, CGNL1, PHLDB2, INPP5K, WASF2, TACSTD2, F11R, ARHGAP6, PPP1R9A, CLASP2, WAS, CORO2B, TMEFF2, ARHGEF18, CLASP1, MYOC |
| negative regulation of stress-activated MAPK cascade | biological process | GSTP1, FOXO1, MYC, FOXM1, IGBP1, QARS1, DUSP10 |
| negative regulation of striated muscle cell apoptotic process | biological process | BMP7, NACA, BAG3, HMGCR |
| negative regulation of striated muscle cell differentiation | biological process | EZH2, YBX1, MSX1 |
| negative regulation of striated muscle contraction | biological process | GRK2, ATP1A2, ATP2A1 |
| negative regulation of striated muscle tissue development | biological process | BMP4, SIRT2, LUC7L, TWIST1, LEF1, SOX15 |
| negative regulation of substrate adhesion-dependent cell spreading | biological process | KANK1, AP1AR, CORO1C, RCC2, FBLN1, EFNA5, POSTN, ITGB1BP1, GBP1, TACSTD2, DMTN, MELTF, ACTN4 |
| negative regulation of superoxide anion generation | biological process | AATF |
| negative regulation of supramolecular fiber organization | biological process | HSPA8 |
| negative regulation of synapse assembly | biological process | PTK2, SLIT1, ROBO2, EPHA7 |
| negative regulation of synapse maturation | biological process | NFATC4 |
| negative regulation of synaptic plasticity | biological process | RIN1, UNC13C, UNC13B, CDK5, RGS14 |
| negative regulation of synaptic transmission | biological process | GNAI1, PCDH17, GNAI2, ADIPOQ, ADNP, BCHE |
| negative regulation of synaptic transmission, dopaminergic | biological process | PTGS2, SLC6A4 |
| negative regulation of synaptic transmission, GABAergic | biological process | HTR1B, NPY5R |
| negative regulation of synaptic transmission, glutamatergic | biological process | PLA2G6, GRIK3, DRD3, HTR1B, DRD2, GRIK2, ATAD1 |
| negative regulation of synaptic vesicle clustering | biological process | PTEN |
| negative regulation of synaptic vesicle exocytosis | biological process | FMR1, RAP1A, RAP1B |
| negative regulation of synaptic vesicle recycling | biological process | STX1B, CYFIP1 |
| negative regulation of syncytium formation by plasma membrane fusion | biological process | RAPGEF3 |
| negative regulation of systemic arterial blood pressure | biological process | BMPR2, GPR37L1, PRCP, CRH, BBS4, TAC4, NTSR1, ARHGAP42, KCNK6, TRPV1 |
| negative regulation of T cell activation | biological process | TGFB1, IL4, FGL1, DUSP22, PELI1, GPNMB, PTPN22, SOCS6, DUSP3, TNFAIP8L2, VTCN1, PAG1, JAK3, PLA2G2D, LAX1 |
| negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological process | HAVCR2 |
| negative regulation of T cell antigen processing and presentation | biological process | HFE |
| negative regulation of T cell apoptotic process | biological process | RAG1, CCL5, PIP, IDO1, PRKCQ, DOCK8, IL7R, SLC46A2 |
| negative regulation of T cell cytokine production | biological process | HFE, HLA-F |
| negative regulation of T cell differentiation | biological process | CD74, IFNL1, DTX1, NRARP, IFNA2 |
| negative regulation of T cell differentiation in thymus | biological process | BMP4, ZC3H8, FOXJ1, IHH |
| negative regulation of T cell extravasation | biological process | IL27RA |
| negative regulation of T cell mediated cytotoxicity | biological process | PPP3CB, PTPRC, IL7R, CEACAM1 |
| negative regulation of T cell mediated immunity | biological process | DUSP22, CLEC4G |
| negative regulation of T cell migration | biological process | APOD, CD200R1, RIPOR2 |
| negative regulation of T cell proliferation | biological process | TGFB1, HLA-DRB1, IL10, IL2RA, HLA-G, SHH, FOXJ1, PAWR, PELI1, IL20RB, DLG5, MARCHF7, IDO1, GPNMB, PTPN6, HAVCR2, CTLA4, SDC4, CD274, CD86, DLG1, MAD1L1, NDFIP1, PDCD1LG2, CLEC4G, VSIG4, PDE5A, SFTPD, VTCN1, TNFRSF21, SPN, PLA2G2D, RIPOR2, CD80 |
| negative regulation of T cell receptor signaling pathway | biological process | EZR, PTPRJ, PRNP, PAWR, DUSP22, ELF1, PHPT1, PTPN2, PTPN6, PTPN22, DGKZ, SLA2, GBP1, DUSP3, CEACAM1, CD160, THY1, LILRB4 |
| negative regulation of t-circle formation | biological process | XRCC5, RTEL1 |
| negative regulation of T-helper 1 cell differentiation | biological process | TNFSF4, JAK3, IL4R |
| negative regulation of T-helper 1 type immune response | biological process | IL33, HAVCR2, IL1RL1 |
| negative regulation of T-helper 17 cell differentiation | biological process | IL4, ZC3H12A, RC3H2, RC3H1, TBX21, ZBTB7B |
| negative regulation of T-helper 17 cell lineage commitment | biological process | TBX21, LOXL3 |
| negative regulation of T-helper 17 type immune response | biological process | IL27RA |
| negative regulation of T-helper 2 cell cytokine production | biological process | TBX21, IFNA2 |
| negative regulation of T-helper 2 cell differentiation | biological process | BCL6, SOCS5, ANXA1, HLX |
| negative regulation of T-helper cell differentiation | biological process | RC3H1 |
| negative regulation of tau-protein kinase activity | biological process | SORL1 |
| negative regulation of telomerase activity | biological process | TP53, SRC, PPARG, POT1, MEN1, PML, ERCC4, MCRS1, CERS1, PINX1 |
| negative regulation of telomerase RNA reverse transcriptase activity | biological process | PARP3 |
| negative regulation of telomere capping | biological process | ATM, NBN, SMG6, RAD50 |
| negative regulation of telomere maintenance | biological process | ERCC1, TERF2IP, ERCC4 |
| negative regulation of telomere maintenance in response to DNA damage | biological process | RTEL1 |
| negative regulation of telomere maintenance via telomerase | biological process | SRC, HNRNPU, GNL3L, HNRNPA1, HNRNPC, DCP2, POT1, TINF2, XRN1, PML, ACD, TENT4B, STN1, PINX1, NAT10 |
| negative regulation of telomere maintenance via telomere lengthening | biological process | PARP1, SLX1A, TNKS, SLX4, TNKS2, ERCC4, MCRS1, PINX1 |
| negative regulation of telomeric DNA binding | biological process | TNKS |
| negative regulation of telomeric RNA transcription from RNA pol II promoter | biological process | ATRX |
| negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled | biological process | SCAF4, SCAF8 |
| negative regulation of testicular blood vessel morphogenesis | biological process | WNT4 |
| negative regulation of testosterone biosynthetic process | biological process | WNT4 |
| negative regulation of the force of heart contraction by chemical signal | biological process | GRK2 |
| negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation | biological process | LRRK2 |
| negative regulation of thrombin-activated receptor signaling pathway | biological process | SNCA, STMN1 |
| negative regulation of thymidylate synthase biosynthetic process | biological process | APBB1 |
| negative regulation of thymocyte apoptotic process | biological process | RAG1, HIF1A, BMP4, EFNA1, ADA, JAK3, RORC |
| negative regulation of timing of anagen | biological process | FERMT1 |
| negative regulation of timing of catagen | biological process | CDH3 |
| negative regulation of tissue remodeling | biological process | AGT |
| negative regulation of tolerance induction | biological process | PDCD1 |
| negative regulation of Toll signaling pathway | biological process | NLRP12 |
| negative regulation of toll-like receptor 2 signaling pathway | biological process | LYN, MFHAS1, TLR6 |
| negative regulation of toll-like receptor 4 signaling pathway | biological process | DAB2IP, BPIFB1, TICAM2, LYN, LILRA2, NR1D1, MFHAS1 |
| negative regulation of toll-like receptor 7 signaling pathway | biological process | LILRA4 |
| negative regulation of toll-like receptor 9 signaling pathway | biological process | LILRA4, PTPRS, GRAMD4 |
| negative regulation of toll-like receptor signaling pathway | biological process | LGR4, IRAK3, GPS2, SMPDL3B, TLR9, LRRC14, OTUD4, PDPK1, ARRB2, CACTIN, TYRO3 |
| negative regulation of tooth mineralization | biological process | BCOR, ASPN |
| negative regulation of TOR signaling | biological process | HIF1A, UBR2, MTM1, SH3BP4, NPRL2, TNFAIP8L1, MAPKAPK5, TSC1, DEPDC5, UBR1, TMEM127, PDCD6, CRYBA1, FNIP1, PRKAA2, FLCN, DEPTOR, ARNTL, NPRL3, TSC2, AKT1S1, TBC1D7 |
| negative regulation of TORC1 signaling | biological process | ATM, SESN3, CASTOR3, DEPDC5, C12orf66, FNIP2, BMT2, SZT2, FNIP1, ITFG2, SESN2, RNF152, KPTN |
| negative regulation of TRAIL-activated apoptotic signaling pathway | biological process | PARK7 |
| negative regulation of transcription by competitive promoter binding | biological process | MUC1, OVOL2, TFAP2A, KDM2A, DACH1, MAD2L2, HHEX, BHLHE41 |
| negative regulation of transcription by RNA polymerase I | biological process | MAF1 |
| negative regulation of transcription by RNA polymerase III | biological process | PRDX5, MAF1, NAB2 |
| negative regulation of transcription by transcription factor localization | biological process | HEY2, HHEX |
| negative regulation of transcription elongation by RNA polymerase I | biological process | POU4F1 |
| negative regulation of transcription elongation from RNA polymerase II promoter | biological process | EZH2, SHH, RNF8, TCERG1, SUPT4H1, HNRNPU, EAPP, NELFCD, RNF168, NELFA, RECQL5, NELFE, NELFB |
| negative regulation of transcription from RNA polymerase II promoter | biological process | TGFB1, TNF, IFNG, IL1B, ESR1, TP53, VDR, VEGFA, ATF3, WT1, SOX9, NRIP1, HIF1A, ESR2, ZEB2, FGFR2, DNMT1, HNF1B, SOX3, STAT1, FASLG, NR0B1, HSF1, MDM2, E2F1, SRY, EZH2, MBD3L1, NODAL, PEG3, MBD2, DNMT3B, MBD1, DMRT1, MTA2, ENO1, PARP1, FGFR1, CTNNB1, STAT3, LEP, RB1, BMP4, C1QBP, NCOA2, ESX1, PROP1, THRB, EZR, NR2F2, PPARG, SOX2, MEF2A, FOXO1, SHH, DICER1, WFS1, ELANE, FGF9, NR1H3, MAEL, PRMT6, SIN3A, TSC22D3, TP63, TCF7L2, MYC, FST, FOXM1, ZNF174, TCERG1, ZBTB5, EED, GLI3, H1-4, SKIL, PEX2, RBL1, TCF7, HDAC4, PER3, UBE2D3, RPS14, SUPT4H1, IRX6, HNRNPU, CBX2, NR1D2, E2F5, OLIG3, ZFPM2, SPEN, OVOL2, ZNF350, BCL11A, EID1, KLF4, PIAS1, HOXD8, YBX3, DDIT3, SMARCA2, MAX, ISL1, E2F4, LRRFIP1, CIR1, ZC3H8, FOXJ1, PAWR, MTA3, PRDM13, ZHX1, CNOT1, PER1, TBX10, SPI1, RFX5, ZNF136, IRX1, SARNP, RBBP7, MIER3, MIER1, NSD1, TRIB3, TXNIP, DUSP22, ZBTB4, STRAP, HCFC2, USP3, HOXA2, RARB, SFPQ, LMO1, BCL6, SMARCA4, RBM10, DR1, SREBF2, NFX1, SMAD4, ZBTB6, CREBRF, HDAC2, GZF1, TAF9B, CTNNBIP1, THAP1, XPO1, SIN3B, TRIM37, EOMES, X |
| negative regulation of transcription from RNA polymerase II promoter by glucose | biological process | FOXA2 |
| negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle | biological process | RB1 |
| negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological process | NCK1, TMBIM6, NCK2 |
| negative regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | SIRT2, CITED2, HIF1AN, VHL |
| negative regulation of transcription from RNA polymerase II promoter in response to stress | biological process | BAG3, DNAJB1, NFE2L1, IMPACT, HSPA1A |
| negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage | biological process | NEDD4, TAF1 |
| negative regulation of transcription from RNA polymerase II promoter involved in heart development | biological process | NACA |
| negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | biological process | MECP2, HEY2, HEY1 |
| negative regulation of transcription initiation from RNA polymerase II promoter | biological process | CTNNBIP1, ZNF451, HEY2 |
| negative regulation of transcription involved in G1/S transition of mitotic cell cycle | biological process | E2F1, RB1, E2F7 |
| negative regulation of transcription of nucleolar large rRNA by RNA polymerase I | biological process | MACROH2A2, MACROH2A1 |
| negative regulation of transcription regulatory region DNA binding | biological process | SIN3A, SRI, REST, MSX1, PER2, SOX11, MAD2L2, HEY2, MSX2, ANKRD33, HEY1, ZNF675, LHX2, GATA1 |
| negative regulation of transcription, DNA-templated | biological process | TGFB1, TNF, TP53, IL4, VDR, ATF3, WT1, AHR, BRCA1, SOX9, SOX10, NOSTRIN, DNMT3L, BIRC5, NR1I2, DNMT1, CDKN2A, NR0B1, MDM2, E2F1, GAS6, EZH2, MBD2, DNMT3B, MBD1, MTA2, ENO1, TNP1, BMP7, CTNNB1, RB1, BMP4, SRC, NRG1, KHDRBS1, NCOA2, ESX1, THRB, NR2F2, YWHAQ, PPARG, SUMO1, FOXO1, CLOCK, KDM5C, CREM, MAEL, PRMT6, SIN3A, ZMYND15, TP63, TCF7L2, FOXM1, ZNF174, PATZ1, RBFOX2, EED, GLI3, HSPA8, TCF7, HDAC4, IKZF1, NR1D2, ZFPM2, USP47, SPEN, OVOL2, ZNF350, ZNF586, KDM5B, EID1, TRIM24, KLF4, CD38, DDIT3, DAP, SMARCA2, TLE1, ELF2, LRRFIP1, SAMD13, TBPL2, CIR1, ZC3H8, DPF1, UIMC1, TSG101, MTA3, BCLAF1, ZHX1, PER1, ZIC2, XRCC5, SPI1, PHC1, CBX1, MBTD1, CBX3, RBBP7, NELFCD, PSPC1, ZNF503, TRIB3, RBM15, PFDN5, ZBTB4, MAGEL2, SNX6, SFPQ, SHC1, BCL6, RFX3, SMARCA4, SMAD4, HDAC2, RSF1, SETDB2, LGR4, GZF1, TCF7L1, BTRC, MAGED1, SIN3B, PDGFB, CRYAB, BCL3, PURA, PPARD, ZNF568, DEPDC1, DAB2IP, ZNF746, BCOR, DEDD2, TRIM11, NKX3-1, SUDS3, FOXN3, KDM4A, SOX18, GCLC, PSMC5, HES1, BEND5, ZNF540, SMARCE1, SAMD11, DMAP1, HDAC9, LOXL2, RUN |
| negative regulation of transformation of host cell by virus | biological process | FBLN1 |
| negative regulation of transforming growth factor beta production | biological process | IL13 |
| negative regulation of transforming growth factor beta receptor signaling pathway | biological process | TGFB1, TGFB3, TGFBR3, HSPA5, CIDEA, SKIL, BAMBI, SNX6, STRAP, PIN1, XBP1, RPS27A, RASL11B, MTMR4, SPRY1, SPRED1, PMEPA1, ASPN, STUB1, SLC2A10, SKI, TGFB1I1, CAV2, SMAD6, ONECUT2, HTRA4, ZNF451, GLG1, LEMD3, SPINT3, BCL9L, UBC, TGFBR1, FAM89B, PPM1A, UBA52, SMAD2, VEPH1, EMILIN1, SPRY2, PEG10, WFIKKN2, TGFBR2, MECOM, CD109, DAND5, WFIKKN1, SMURF2, ONECUT1, ENG, ADAMTSL2, ZBTB7A, UBB, VASN, HTRA1, PRDM16, PDPK1, LDLRAD4, HTRA3, SMAD3, CHST11, SNX25, TP53, HSPA1A, NKX2-1, CAV1 |
| negative regulation of transforming growth factor beta1 production | biological process | LAPTM4B, TYROBP, CD2AP, FURIN |
| negative regulation of transforming growth factor beta2 production | biological process | CDH3 |
| negative regulation of transforming growth factor-beta secretion | biological process | FN1, FBLN1 |
| negative regulation of translation | biological process | WT1, FMR1, GAPDH, NANOS2, NANOS1, NANOS3, DDX3X, TYMS, SHMT1, IGF2BP2, CNOT1, FXR1, DHX36, CNOT8, EPRS1, SYNCRIP, RACK1, PURA, EIF2AK1, RPS3, TIA1, RPL13A, EIF4EBP2, ZNF540, GZMB, IREB2, TSC1, EIF4ENIF1, YBX1, ILF3, CAPRIN1, CNOT10, EIF4EBP1, BTG2, GRB7, EIF4E, CNOT9, CELF4, SAMD4A, EIF4E2, DHFR, RGS2, FXR2, RIDA, XRN1, ENC1, RNF139, RBM4, TOB1, LARP1, CPEB3, MALSU1, CNOT2, TRIM71, DAPK1, EIF2AK2, NCL, IGF2BP3, GIGYF2, CNOT3, ANG, IGFBP5, CAPRIN2, INPP5E, CALR, EIF4A3, SAMD4B, IGF2BP1, PUS7, EIF2AK3, RARA, PCIF1, LIN28A |
| negative regulation of translation in response to endoplasmic reticulum stress | biological process | SESN2 |
| negative regulation of translation in response to oxidative stress | biological process | PML |
| negative regulation of translation in response to stress | biological process | RBM4, EIF2AK3 |
| negative regulation of translational elongation | biological process | SRP9 |
| negative regulation of translational frameshifting | biological process | SHFL |
| negative regulation of translational initiation | biological process | FMR1, EIF3E, BANK1, EIF4EBP2, EIF4EBP1, RBM4, AGO2, C8orf88, LARP1, TPR |
| negative regulation of translational initiation by iron | biological process | EIF2AK1 |
| negative regulation of translational initiation in response to stress | biological process | ATF4, EIF2S1, EIF2AK3 |
| negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | FSTL3 |
| negative regulation of transmembrane transport | biological process | CTTNBP2NL |
| negative regulation of transmission of nerve impulse | biological process | GLRA1, AVP, HCRT |
| negative regulation of transport | biological process | ARL6IP5, YRDC, TRAT1, RSC1A1 |
| negative regulation of transporter activity | biological process | INSR, CTTNBP2NL, SNCA, WWP2, NDFIP1, NDFIP2 |
| negative regulation of transposition | biological process | APOBEC3F, MORC1, APOBEC3G, APOBEC3A, SIRT7, APOBEC3C, TEX19, APOBEC3B |
| negative regulation of transposition, RNA-mediated | biological process | MOV10, TUT4, TUT7 |
| negative regulation of transposon integration | biological process | ZNF91, ZNF93 |
| negative regulation of triglyceride biosynthetic process | biological process | FBXW7, SIK1 |
| negative regulation of triglyceride catabolic process | biological process | GPLD1, SORL1, PIK3CG, APOC3 |
| negative regulation of triglyceride metabolic process | biological process | ESR1, APOBEC1 |
| negative regulation of trophoblast cell migration | biological process | TIMP1, NODAL, ACVR1C, ARHGDIB, CALR |
| negative regulation of tubulin deacetylation | biological process | BEX4, FRY, PRKAA2, TPPP |
| negative regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological process | LTF |
| negative regulation of tumor necrosis factor biosynthetic process | biological process | IL10, GHRL, ERRFI1, BCL3, GHSR |
| negative regulation of tumor necrosis factor production | biological process | IL10, AXL, HSF1, GAS6, TLR4, GSTP1, CIDEA, SELENOS, ZC3H12A, LGALS9, AKAP8, ORM1, CD34, GPNMB, PTPN6, ADIPOQ, HAVCR2, IRAK3, ILRUN, PTPN22, CHRNA7, LILRA4, NR1H4, TWIST1, TREM2, C5AR2, BPI, CD33, CLEC4A, SLAMF1, POMC, ARRB2, LBP, CACTIN, VSIR, MC1R, RARA |
| negative regulation of tumor necrosis factor secretion | biological process | ZC3H12A, GHSR, DEFB114, NR1H4, IL27RA |
| negative regulation of tumor necrosis factor superfamily cytokine production | biological process | CD274 |
| negative regulation of tumor necrosis factor-mediated signaling pathway | biological process | GAS6, GSTP1, CCDC3, PTPN2, ADIPOQ, PYDC1, APOA1, GPS2, NR1H4, CARD16, PELI3, CARD8, TRAIP, PIAS4, ZNF675 |
| negative regulation of type 2 immune response | biological process | BCL6, IFNL1, NDFIP1, STAT6, IL27RA |
| negative regulation of type B pancreatic cell apoptotic process | biological process | WFS1, TCF7L2, PDX1, NEUROD1, CAST |
| negative regulation of type B pancreatic cell development | biological process | GSK3B |
| negative regulation of type B pancreatic cell proliferation | biological process | NUPR1, WDR13 |
| negative regulation of type I hypersensitivity | biological process | FCGR2B |
| negative regulation of type I interferon production | biological process | TBK1, ITCH, IFIH1, TRAF3IP1, PIN1, TRIM25, NLRX1, UBA7, HAVCR2, DHX58, UFD1, IKBKE, RNF135, TAX1BP1, ILRUN, ISG15, CYLD, UBE2L6, PCBP2, OTUD5, IRF3, RNF125, RNF216, NPLOC4, HERC5, MAVS |
| negative regulation of type I interferon-mediated signaling pathway | biological process | YTHDF3, ADAR, PTPN2, SAMHD1, YTHDF2, TTLL12, MUL1, TREX1, CACTIN |
| negative regulation of type IV hypersensitivity | biological process | IL20RB |
| negative regulation of tyrosine phosphorylation of STAT protein | biological process | PPP2CA, SH2B3, INPP5F, PTPN2, SOCS1, PARP14, PIBF1, PPP2R1A, SOCS3, CAV1 |
| negative regulation of tyrosine phosphorylation of Stat3 protein | biological process | NF2 |
| negative regulation of tyrosine phosphorylation of Stat5 protein | biological process | NF2 |
| negative regulation of ubiquitin protein ligase activity | biological process | RPL5, RPS7, RPL11, MAD2L1, USP44, MAD2L2, RPL23 |
| negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological process | CDK1, CCNB1, CDC20, PSMA3 |
| negative regulation of ubiquitin-protein transferase activity | biological process | CDKN2A, PARK7, DTX3L, BAG5, PSEN1, ABL1, LIMK1 |
| negative regulation of ubiquitin-specific protease activity | biological process | PARK7, UBXN1 |
| negative regulation of ureter smooth muscle cell differentiation | biological process | SHH |
| negative regulation of urine volume | biological process | OXT, ADCY6, MLLT6, AVPR2, SLC4A1 |
| negative regulation of uterine smooth muscle contraction | biological process | ADRA2C |
| negative regulation of vascular associated smooth muscle cell migration | biological process | TPM1, ADIPOQ, MEF2C, PRKG1, MYOCD |
| negative regulation of vascular endothelial cell proliferation | biological process | MEF2C, COL4A3, CCL2 |
| negative regulation of vascular endothelial growth factor production | biological process | SARS1, NUTF2 |
| negative regulation of vascular endothelial growth factor receptor signaling pathway | biological process | DAB2IP, HGS, CNMD, NEDD4, PDCD6, PTPN1, EMILIN1, HHEX, EPN2, NIBAN2 |
| negative regulation of vascular endothelial growth factor signaling pathway | biological process | DCN, XDH, ADGRA2, DAB2IP, SEMA6A, SPRY2, HRG |
| negative regulation of vascular permeability | biological process | ADM, PTPRJ, AKAP12, DDAH1, CLDN5, ARHGAP35, RAMP2, AMOT, ANGPT1, PDE3A, CEACAM1, PDE2A, ADORA2A, SLIT2 |
| negative regulation of vascular smooth muscle cell differentiation | biological process | PDGFB, NFATC1, NFATC3, PDCD4, NFATC2 |
| negative regulation of vascular smooth muscle cell proliferation | biological process | TPM1, ADIPOQ, MEF2C, PDCD4, CDKN1B, PRKG1, CNN1, MYOCD, CDKN1A, GPER1 |
| negative regulation of vascular smooth muscle contraction | biological process | DOCK5, ARHGAP42, DOCK4 |
| negative regulation of vascular wound healing | biological process | SERPINE1, SLC12A2, ALOX5, TNF |
| negative regulation of vasculogenesis | biological process | XDH, RTN4 |
| negative regulation of vasoconstriction | biological process | ADM, HIF1A, LEP, BMPR2, CX3CL1 |
| negative regulation of vasodilation | biological process | CRP |
| negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly | biological process | SVIP |
| negative regulation of ventricular cardiac muscle cell action potential | biological process | BIN1 |
| negative regulation of very-low-density lipoprotein particle clearance | biological process | APOC1, LRPAP1, APOC3 |
| negative regulation of very-low-density lipoprotein particle remodeling | biological process | APOA1, APOC3 |
| negative regulation of vesicle fusion | biological process | TBC1D4, CORO1A |
| negative regulation of viral entry into host cell | biological process | SNX3, TRIM25, TRIM11, TRIM8, FCN3, TRIM10, IFITM3, IFITM1, IFITM2, FCN1, MID2, IFNA2, APCS, TRIM5, TRIM31 |
| negative regulation of viral genome replication | biological process | TNF, LTF, CCL5, SLPI, OAS1, BST2, APOBEC3F, ISG20, ZC3HAV1, AEN, SRPK1, SRPK2, ILF3, OASL, RSAD2, IFIT1, RNASEL, MX1, ISG15, IFITM3, SHFL, FAM111A, PLSCR1, IFITM1, IFITM2, IFI16, APOBEC3G, APOBEC3A, TNIP1, APOBEC3C, EIF2AK2, IFNL3, PROX1, PARP10, OAS2, MAVS, TRIM6, BTBD17 |
| negative regulation of viral life cycle | biological process | IL32 |
| negative regulation of viral process | biological process | LTF, APOBEC3F, APOBEC3G, APCS, MBL2 |
| negative regulation of viral release from host cell | biological process | TRIM13, TRIM25, TRIM11, TRIM15, TRIM32, TRIM8, PML, MID2, TRIM21, TRIM35, CHMP3, TRIM5 |
| negative regulation of viral transcription | biological process | TRIM13, TRIM11, UBP1, TRIM32, TRIM8, SP100, IFITM3, ZFP36, TRIM62, MID2, TRIM21, TRIM14, TRIM31 |
| negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway | biological process | TSPAN6 |
| negative regulation of vitamin D biosynthetic process | biological process | GFI1 |
| negative regulation of vitamin D receptor signaling pathway | biological process | KANK2 |
| negative regulation of voltage-gated calcium channel activity | biological process | FMR1, GNB5, CRHR1, DRD3, CACNB3, DRD2, OPRL1, CBARP, GPR35, DRD4 |
| negative regulation of voltage-gated potassium channel activity | biological process | KCNAB1, KCNE3 |
| negative regulation of white fat cell proliferation | biological process | IL4 |
| negative regulation of Wnt signaling pathway | biological process | SHH, FGF9, TLE1, CUSTOS, CTNNBIP1, CER1, RACK1, GRB10, NFATC1, FRZB, CITED1, RNF43, DKK1, CBY1, WIF1, APC, SOSTDC1, SIX3, NLK, TRABD2B, HMGXB4, NXN, NFATC4, DACT1, GSC, LRP1, VGLL4, SFRP2, LZTS2, DKK4, HIC1, TSKU, TAX1BP3, SFRP5, TSC2, SFRP4, APCDD1, APC2, TRABD2A, NKD2, CHD8, NOTUM, MDFI, ZNRF3, APCDD1L, WWOX, DKK2, NKD1 |
| negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis | biological process | SFRP5 |
| negative regulation of Wnt signaling pathway involved in heart development | biological process | ALPK2, BMP2 |
| negative regulation of Wnt-Frizzled-LRP5/6 complex assembly | biological process | DKK1 |
| negative regulation of wound healing | biological process | SERPINE1, GJA1, WNT4, WFDC1, HMGCR, ALOX5, EPPK1, CASK, CD109, APCS, FGF2, CRK, AJAP1, SMAD3 |
| negative regulation of wound healing, spreading of epidermal cells | biological process | PHLDB2, CLASP2, CLASP1 |
| negative regulation of zinc ion transmembrane import | biological process | SLC30A1 |
| negative stranded viral RNA replication | biological process | ATG5, ATG16L2, ATG16L1 |
| negative T cell selection | biological process | THEMIS |
| negative thymic T cell selection | biological process | FAS, SHH, GLI3, AIRE, CD74, ZAP70, ATG5, PTPRC, CD3E, CCR7, CD28, DOCK2 |
| nephric duct development | biological process | HNF1B |
| nephric duct elongation | biological process | LHX1 |
| nephric duct formation | biological process | HNF1B, GATA3 |
| nephric duct morphogenesis | biological process | GATA3, LHX1, EPHA4, EFNB2, EPHA7 |
| nephrogenic mesenchyme morphogenesis | biological process | BMP7, SMAD4 |
| nephron development | biological process | NUP85, NUP107, DCHS1, WNT4, NUP133, SIX2, DLL1, ITGA3, JAG1, NUP160 |
| nephron morphogenesis | biological process | SIX2 |
| nephron tubule development | biological process | WNT6 |
| nephron tubule epithelial cell differentiation | biological process | MEF2C, MTSS1 |
| nephron tubule formation | biological process | CTNNB1, WNT6 |
| nephron tubule morphogenesis | biological process | WNT9B |
| nerve development | biological process | SEMA3A, DICER1, SEMA3F, CTSV, NTF4, NRP2, AFG3L2, ILK, NRTN, DAG1, NGFR, NTF3, NRP1 |
| nerve growth factor processing | biological process | NGF, PCSK6, FURIN |
| nerve growth factor production | biological process | PCSK6, FURIN |
| nerve growth factor signaling pathway | biological process | RAP1A, NTRK1, RAPGEF2, NTF4, RAPGEF1, KIDINS220, SORT1, NTF3, CORO1A, MAGI2 |
| nerve maturation | biological process | DAG1 |
| nervous system development | biological process | INHBA, VEGFA, BDNF, BAX, NDRG2, ZEB2, APOB, ERBB2, AKT1, GSK3B, NODAL, MTR, SEMA7A, APP, CTNNB1, STAT3, PTEN, SEMA3A, BRSK2, GFRA1, SLC7A5, NRG1, FGF17, CDC42, RAP1A, MEF2A, CDC20, NTRK1, INHA, DYNLT1, DSCAML1, DPF3, SDHA, GDNF, SEMA3E, RBFOX2, RYK, HDAC4, FGF12, ROR1, CAMK2B, ISLR2, SIAH1, CNTN4, NRSN1, SEMA6D, BTBD3, NUMBL, KIF2A, SMARCA2, NDP, DYRK1A, DPYSL2, DPF1, NDN, OLFM1, IGF2BP2, FZD9, KALRN, NKX2-2, ZIC2, ACTL6A, CHN1, PPT1, NAP1L1, ZC3H12A, NAV1, MDGA1, RTN4, FEZ2, NPTN, CIT, ACVR1B, SMARCA4, NRG3, ARHGEF7, RBM45, BHLHE22, NELL1, PPP1R9B, PHOX2B, NEUROG2, BEX1, ALK, UTP11, RAPGEF2, BZW2, CER1, LGI1, PTN, NUMB, PURA, CYB5D2, IRF2BPL, TMEM14B, ATXN10, RAPGEFL1, TRIM3, SCRG1, NEURL1, EPHB2, GPM6A, HSD17B7, ERCC6, HES1, PRKD1, CTF1, TTLL7, SETX, CAMK1D, SMARCE1, NEUROD6, FEV, SEMA4C, INTU, SDC2, BMPR1A, SLC1A2, MYT1, ARID1B, NRG4, TSC1, ASCL2, ABI2, LRCH4, GJB1, SMPD1, GPM6B, CCDC88A, SMARCD3, GLDN, GPSM1, CHERP, NEUROG1, HES6, DISC1, SEMA4G, NINJ2, PCDHB4, SLIT1, STMN1, CNTFR, VLDLR, ELAVL3, NRN1L, SE |
| nervous system process involved in regulation of systemic arterial blood pressure | biological process | MECP2, CALCA, DRD2 |
| netrin-activated signaling pathway | biological process | SHTN1, PTK2, DCC, UNC5C, UNC5D, DSCAM, UNC5CL, UNC5B, UNC5A |
| neural crest cell development | biological process | SOX9, MAPK3, MAPK1, EDNRA, NRG1, ALDH1A2, FAM172A, BMPR1A, KLHL12, SOX11, PDCD6, TAPT1, FOXC2, TCOF1, RDH10, EDN1, KBTBD8, FOXC1, CYP26C1, PEF1, HAND2 |
| neural crest cell differentiation | biological process | SMAD4, WNT10A, FRZB, MEF2C, LRP6, FBXL17, HTR2B |
| neural crest cell fate specification | biological process | GSC |
| neural crest cell migration | biological process | KITLG, SOX10, HIF1A, ZEB2, SEMA7A, SEMA3A, SHH, GDNF, SEMA3E, SEMA6D, OVOL2, ISL1, SEMA3F, CORO1C, ACVR1, SEMA4C, SEMA3G, SEMA4G, SEMA4D, SMO, EDNRB, NRP2, SEMA6A, EFNB1, NRTN, RET, SEMA3B, SEMA3C, SEMA6C, GBX2, PHACTR4, SEMA6B, LAMA5, SEMA4B, EDN3, HTR2B, ALX1 |
| neural crest cell migration involved in autonomic nervous system development | biological process | SEMA3A, SEMA3F, PHOX2B, NRP2, NRP1 |
| neural crest cell migration involved in heart formation | biological process | FOLR1 |
| neural crest cell migration involved in sympathetic nervous system development | biological process | SEMA3A |
| neural crest formation | biological process | KLHL12, LRP6, PDCD6, TCOF1, KBTBD8, PEF1 |
| neural fold bending | biological process | LUZP1 |
| neural fold elevation formation | biological process | HIF1A, BMP5 |
| neural fold formation | biological process | NODAL, OVOL2 |
| neural nucleus development | biological process | HOXB2 |
| neural plate anterior/posterior regionalization | biological process | CELSR2 |
| neural plate axis specification | biological process | C2CD3, PTCH1 |
| neural plate development | biological process | CTNNB1 |
| neural plate mediolateral regionalization | biological process | BMPR1A |
| neural plate morphogenesis | biological process | FGF8, EPB41L5 |
| neural plate pattern specification | biological process | BMPR1A |
| neural precursor cell proliferation | biological process | ZNF503, RPGRIP1, TMEM14B, KCTD13, TARBP2, ORC3, WDR47, EPHB1, SLC39A5, MELK, Grn |
| neural retina development | biological process | ACTL6A, SMARCA4, GPM6A, RAB11FIP4, SMARCD3, CASP2, PSEN1, TGFB2, ATP2B1, RPE65, SLC17A7 |
| neural tube closure | biological process | ADM, ZEB2, MTHFD1, BMP4, RPS7, SHROOM3, IFT57, COBL, TULP3, BCL10, PTK7, RALA, VASP, PRKACB, DLC1, SEMA4C, SPINT2, MTHFD1L, TSC1, ARHGAP35, SPINT1, LIAS, SDC4, FZD3, SKI, BBS4, DEAF1, SCRIB, TMED2, LRP6, CELSR1, SALL4, TGFB2, LRP2, KIF20B, VANGL2, SEC24B, TEAD2, TWIST1, SUFU, DVL2, ABL1, TRAF6, ARID1A, TRIM71, MED12, SFRP2, IFT122, STIL, KAT2A, FZD6, TSC2, PHACTR4, FUZ, RARG, PRICKLE1, PLXNB2, PTCH1, ST14, GRHL3, CC2D2A, IFT172, LHX2, RARA, ALX1 |
| neural tube development | biological process | ALDH1A2, PKD1, GLI3, TCF7, TULP3, DVL1, HES1, INKA1, DCHS1, INTU, NOTCH1, PKD2, SALL4, C2CD3, NUP133, ITPK1, TBC1D32, PHGDH, ZFP36L1, TRIM71, SALL2, DACT1, MED12, SFRP2, PLOD3, EPHA2, FKBP8, STIL, SEMA3C, GDF7, PROX1, PLXNA2, GLI2, NF1, AMBRA1, IFT172 |
| neural tube formation | biological process | STK3, MIB1, IFT52, TULP3, STK4, TCTN1, SOX11, SOX4, PTCH1, IFT172 |
| neural tube patterning | biological process | TRAF3IP1, ARL13B, DZIP1L, TMEM107, TBC1D32, PTCH1, RPGRIP1L |
| neuroblast delamination | biological process | AKNA |
| neuroblast differentiation | biological process | BCHE, SIX3 |
| neuroblast division in subventricular zone | biological process | NUMBL, NUMB, AKNA |
| neuroblast fate determination | biological process | ASCL1 |
| neuroblast migration | biological process | SIX3, PDS5B |
| neuroblast proliferation | biological process | SHH, NUMBL, FZD9, NUMB, NEUROD4, ASCL1, ID4, FRS2, EML1, DAGLB, HHIP, NDE1, PLXNB2, KCNA1, DAGLA |
| neuroendocrine cell differentiation | biological process | BCCIP, WNT11 |
| neuroepithelial cell differentiation | biological process | FGF8, EMX1, B9D1, SOX11, ABL1, SOX4 |
| neurofilament bundle assembly | biological process | NEFH, NEFM, NEFL |
| neurofilament cytoskeleton organization | biological process | SOD1, NEFH, ATP8A2, INA, NEFL |
| neurogenesis | biological process | NRG1, KIF3A, XRCC2, RYK, BTBD3, TRAK2, CXCR4, PRDM13, NAV1, RARB, BHLHE22, EOMES, ERCC6, SMARCE1, DCHS1, CDK5RAP2, LEMD2, NEUROG1, WNT3A, CEP120, EPHB1, NAV2, TRAK1, PSEN1, ASCL1, WDR62, NEUROD1, NUP133, RITA1, BTBD1, FOXG1, PRDM6, PHGDH, SPOCK1, SIX1, LPAR1, BTBD6, ROGDI, PRDM12, FABP7, NAV3, DAGLB, VXN, PRDM5, GRIN2A, MESP1, CHAC1, NTN5, BTBD2, PRDM16, OMP, PCSK9, DAGLA, CNTN6, LHX2, HAP1 |
| neurohypophysis development | biological process | OTP, POU3F2 |
| neuroinflammatory response | biological process | ADCY8, TREM2 |
| neuroligin clustering involved in postsynaptic membrane assembly | biological process | NRXN1, NRXN2, MAGI2 |
| neurological system process | biological process | WFS1, GABRB1, WDR19, CHRNA5, GABRA2, CHRNE, HTR3B, HTR3A, CACNG2, PSAP, CHRNA2, GABRG2, GABRB3, GLRA3, CHRNB1, GABRA5, CHRNA7, CHRND, CHRFAM7A, CHRNA10, GABRB2, GABRA4, GABRG1, CHRNA3, ADGRV1, GABRP, GABRD, HTR3E, GLRA1, CHRNA6, GABRR2, CHRNG, GABRA1, CHRNB2, GABRA3, CHRNA4, ZACN, GABRQ, GABRR3, GABRG3, CHRNA1, GLRA2, CHRNB4, GM2A |
| neuromast hair cell development | biological process | SLC44A4 |
| neuromuscular junction development | biological process | ERBB2, FNTA, KALRN, ANK3, ALS2, CACNG2, DVL1, UTRN, COL4A1, ZC4H2, NEDD4, CACNA2D2, UNC13C, AFG3L2, UNC13B, PPFIBP2, RER1, TNC, CACNB4, TMEFF1, PDZRN3, CACNB1, TMEFF2, CACNB3, AGRN, DOK7, UNC13A, P2RX2, CHRNA1, CACNB2, LRRK2, PPFIBP1 |
| neuromuscular process | biological process | HEXB, FGF12, OPA3, GRIN1, ZMPSTE24, AARS1, CHRND, MECP2, SPART, HOXC10, UBA5, MYCBP2, HOXD10, GLRA1, POMK, RAC3, COMP, KCNAB2, KCNA1, STRA6, CHRNA1, UCHL1 |
| neuromuscular process controlling balance | biological process | APP, HEXB, NBN, GAA, RBFOX2, MYH10, JPH4, BCR, ABR, NLGN2, JPH3, NEUROG1, PSAP, AARS1, REST, SLC1A3, ALDH1A3, FOXS1, IGDCC3, GPR88, CAMTA1, GRIN2C, TPP1, BLOC1S4, ABL1, TIFAB, DLG4, CLN3, POU4F2, RAC3, GIGYF2, NR4A3, ADCY5, SHANK1, CNTNAP1, HERC1, NEFL, GM2A |
| neuromuscular process controlling posture | biological process | GAA, PRRT2, ADARB1, PNKD, MECP2, ATP8A2, GCH1, SCN1A, GLRA1, TCF15, CNTNAP1 |
| neuromuscular synaptic transmission | biological process | ETV5, CHRNA5, ADARB1, CHRNE, FCHSD2, RIMBP2, CHRNA2, DTNA, KIF1B, CHRNB1, CHRND, RIMBP3B, CHRNA3, EGR3, CHRNA6, SLC5A7, CHRNG, CHRM1, CHRNB2, CHAT, CHRNA4, STAC3, P2RX3, MYLK2, P2RX2, CHRNA1, CHRNB4 |
| neuron apoptotic process | biological process | BCL2, FAS, LIG4, BAX, CASP3, ATM, GAPDH, APP, RB1, TP63, SIAH1, MAX, XIAP, CIT, NAE1, OXR1, AIFM1, USP53, PSEN1, BID, BNIP3, FAM162A, SCN2A, NLRP1, BOK, DIABLO, ERBB3, BCL2L1, TNFRSF21, CDK5, POLB, NGFR, PIGT, GRIK2, TP53 |
| neuron cell-cell adhesion | biological process | CNTN4, ASTN2, NLGN4X, NCAM2, NRXN1, NLGN2, NINJ2, NRXN2, NRXN3, NLGN4Y, CDK5R1, ASTN1, RET |
| neuron cellular homeostasis | biological process | HAAO, SLC6A2, FGGY, PRKN, TAOK1, NELL2, DNAJB2, SLC8A2, CHRNA1, TYRO3 |
| neuron death | biological process | PLAU, BAG5, SLC9A1, NAMPT, CBL, DPYSL4, LRRK2 |
| neuron death in response to oxidative stress | biological process | ENDOG, TBC1D24 |
| neuron development | biological process | LIF, SOX3, NDN, PBX2, PPT1, ALK, XBP1, DPYSL3, CTF1, HTRA2, PBX3, VSX1, GABRB3, MEF2C, MFSD8, WNK1, SYN1, GABRA5, NEUROD4, NR2F6, DGKG, PSEN1, ASCL1, GABRB2, NEUROD1, PBX1, TGFB2, THOC2, TENM2, ATP8A2, MYT1L, TDP2, POU3F2, SCYL1, PPP1R9A, PITX3, EN1, SCYL3, PBX4, SRF, GFRA3, EN2, SECISBP2, NRP1, GLI2, IHH, TENM4, CRMP1, TENM3, HS6ST1, PACSIN1, CNTF, MAP1B, UGCG |
| neuron differentiation | biological process | DNMT1, CASP3, MBD1, CTNNB1, BRSK2, IL1RAPL1, RB1, EMX1, TUBB3, ALDH1A2, DYNC2H1, RYK, IRX6, NNAT, GPC2, NIF3L1, ISL1, BAIAP2, IRX1, PIN1, NLGN4X, PHOX2B, NEUROG2, FZD8, LHX3, FZD4, EOMES, RTN1, BTG4, EFNA1, ERCC6, CTF1, ADNP2, WNT10A, HDAC9, ACSL3, WNT7B, HIPK1, ASCL2, XRN2, ITM2C, LMX1B, WNT4, FZD2, NEUROG1, WNT9B, S1PR1, NOTCH1, WNT3A, RUNX1, IER2, FZD3, SNPH, GAS7, GATA3, COPS2, IRX4, ID3, MEF2C, NTRK2, TBR1, AIFM1, ATF4, WNT2B, WNT8B, INSM2, HOXD1, FZD7, NR4A2, LHX1, PSEN1, ASCL1, BTG2, EMX2, IRX2, SOX11, TENT2, MECP2, CDK5R1, HIPK2, SMARCA1, INSM1, MYT1L, ABL1, RBPJ, ACSL4, POU3F2, GATA2, IRX5, NAPA, IRX3, POU4F1, LDB1, BARHL2, OPHN1, WNT11, MAP2K1, EN1, POU4F2, RUNX2, LHX5, MYEF2, VAX2, TRPC5, FUT9, RET, EPHA2, FZD5, VXN, WNT10B, CDK5, EN2, LMX1A, PIGT, HOXC8, GSX1, NGRN, HDAC5, ATP2B2, PCSK9, DOK5, WNT9A, WNT3, BRSK1, LHX4, FZD1, WNT6, WNT7A, EDN3, PTPRD, TRAPPC9, WNT5B, CNTN6, LHX2, NRBP2, WNT16 |
| neuron fate commitment | biological process | BMP4, NRG1, SHH, GLI3, PAX7, ISL1, ZNF521, SMAD4, OLIG1, NOTCH1, ASCL1, MYT1L, POU3F2, TGFBR1, GBX1, GATA2, NOTCH3, ID2, LBX1, GSX1, FOXN4, NKX2-1, PTF1A |
| neuron fate determination | biological process | CDC42, PRRX1, FOXG1, LBX1 |
| neuron fate specification | biological process | ISL1, NKX2-2, FEV, FOXA1, ASCL1, MYT1L, POU3F2, POU4F1, SIX1, EYA1, DLL1 |
| neuron maturation | biological process | RB1, FEV, VSX1, NR4A2, MECP2, B4GALT6, IRX5, B4GALT5, RET, LGI4, ACTL6B, SRRM4 |
| neuron migration | biological process | BAX, HSP90AA1, AXL, GAS6, FGFR1, CTNNB1, SEMA3A, TUBB2B, GJA1, NR2F2, PEX7, PCM1, ASTN2, MYH10, CXCR4, NDN, NAV1, MDGA1, MARK2, POMGNT2, AUTS2, PHOX2B, RAPGEF2, KIRREL3, GPM6A, PTK2, ASPM, MATN2, CCKAR, TUBB2A, DISC1, SH3RF1, APBB2, PEX13, UNK, FZD3, NTN1, GATA3, CNTN2, MEF2C, NTRK2, DNAAF4, BBS4, DCDC2, SDCCAG8, NRCAM, NEUROD4, NR4A2, PSEN1, ASCL1, KIAA0319, CELSR2, CELSR1, DCX, DCC, CHL1, NRP2, YWHAE, CDK5R1, CDKL5, RAC1, TWIST1, PRKG1, TOP2B, LRP12, DCLK1, GATA2, SPOCK1, USP9X, CDK5R2, BARHL2, TBX20, POMK, ASTN1, SRF, ELP3, CCK, CDK5, ARX, GFRA3, CRK, ALKBH1, NDE1, NRP1, ACAP3, ITGA3, CELSR3, CXCL12, DNER, ADGRL3, MARK1, SATB2, CRKL, MAP1B, RELN, TRIM46, NDNF, FBXO45, NKX2-1, CCR4 |
| neuron projection arborization | biological process | ROCK1, PAK6, LRP2, LRRK2 |
| neuron projection development | biological process | IL6, SEMA7A, APP, ITGB1, GNAO1, FGFR1, PTEN, RB1, CDH1, NCAM1, FLRT3, GDNF, AREG, RYK, SEPTIN2, CAMSAP1, BLOC1S2, CNTN4, STMND1, MYH10, RAB11A, ARFGEF1, CAMSAP2, PPP1R9B, RAPGEF2, LGI1, UHMK1, SH3GL2, ATXN10, SNAPIN, GPM6A, ERCC6, STX3, MAP4, MANF, WNT7B, NRXN1, WDR5, MATN2, GPM6B, NPY, STMN1, RAB35, EFHD1, TBC1D23, STMN3, BLOC1S1, CNTN2, CNTN1, NEDD4, ROCK1, DTNBP1, ULK1, HMGB1, UCN, BTG2, ADGRF1, CYFIP2, VAPA, NCDN, CNTNAP2, FRY, CHL1, MAP2, MECP2, CDK5R1, TMEM108, GDPD5, CLMN, DOCK7, PTPRM, ATP8A2, BLOC1S4, CDNF, CYFIP1, LYN, TNC, LRP12, PHGDH, WASF1, BLOC1S6, HDGFL3, UBE4B, POU4F1, PRMT1, PRDM12, PPP1R9A, PSD, PQBP1, OPHN1, LAMB1, NRTN, SRF, RAC3, CDK5, SAMD14, EPHA8, ALKBH1, BICDL1, L1CAM, USP21, CNTNAP1, RASGRF1, HERC1, UNC5A, GPRIN1, ATCAY, MICALL2, MICALL1, CAMSAP3, PTK2B, TBC1D24, MYOC, FRYL, AGER |
| neuron projection extension | biological process | EMX1, FLRT3, TNN, IQGAP1, FLRT1, NRN1L, POSTN, PAK6, TIAM1, CPNE1, PLXNA1, PRKCZ, ALCAM, PLXNA3, IMPACT |
| neuron projection fasciculation | biological process | EPHA4, AMIGO1 |
| neuron projection guidance | biological process | ARHGAP35, PLXNA1, EPHA4, DPYSL4, PLXNA3 |
| neuron projection maintenance | biological process | PRNP, ABCD2, PSEN1, ATP1A3, INS, ABCD1 |
| neuron projection morphogenesis | biological process | WEE1, CLU, BMP7, BRSK2, NGF, GJA1, DICER1, DYNLT1, SHTN1, STK3, ALS2, NCKAP1, STK4, DAB2IP, KIRREL3, ANKRD27, GPM6A, EPB41L3, WNT7B, NTF4, CTTN, SLIT1, NEK3, GAS7, MAP4K4, DTNBP1, ZNF335, DBNL, KLK8, CNTNAP2, SRGAP2, KIF20B, SLITRK6, MAP1S, TNIK, SGK1, ATP7A, DCLK1, PLXNA4, HCLS1, ILK, MYO16, MNX1, NCKAP1L, SLC9A6, CDK5, NTF3, NYAP1, UBB, PLXNB1, ADORA2A, NBL1, CNTNAP1, MINK1, BRSK1, PACSIN1, LRRK2, ZSWIM6, NEFL, UGT8 |
| neuron projection regeneration | biological process | APOE, ADM, PTPRF, ULK1 |
| neuron projection retraction | biological process | EPHB2 |
| neuron recognition | biological process | CXCR4, OPCML, NTM, CNTNAP2, PCDH12 |
| neuron remodeling | biological process | APP, ANKS1A, NTN4, ADGRB3, FARP2, C1QA, EPHA8, SCARF1 |
| neuron-glial cell signaling | biological process | ADRA1A, GABBR1, ADRA1D, ADRA1B |
| neuron-neuron synaptic transmission | biological process | PTEN, VDAC1, ARID1B, KIF1B, DRD2 |
| neuronal action potential | biological process | CATSPER4, SCN11A, ANK3, MYH14, KCNMB3, KCND2, GPR88, SCN2A, CACNA1G, SCN1A, CACNA1I, DRD1, CACNA1H, KCNA2, P2RX4, SCN4A, P2RX3, KCNA1, SCN5A, GRIK2, KCNMB4, SCN10A, CHRNA1, SCN8A, GPER1 |
| neuronal action potential propagation | biological process | CLCN1, NTRK2, SCN1B, NRCAM, FKBP1B, SCN1A, CNTNAP1 |
| neuronal dense core vesicle exocytosis | biological process | UNC13B, UNC13A |
| neuronal ion channel clustering | biological process | PICK1, MTCH1 |
| neuronal signal transduction | biological process | OLFM1, P2RY11, RTN4R, NRXN1, MACO1, KCNA1 |
| neuronal stem cell population maintenance | biological process | SOX2, FOXO1, PCM1, FANCD2, HES1, ASPM, SS18, HOOK3, NOTCH1, REST, MCPH1, PRRX1, SRRT, FANCC, DLL1, FOXO3, PROX1, JAG1, IGF2BP1 |
| neuronal-glial interaction involved in cerebral cortex radial glia guided migration | biological process | LAMB1 |
| neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration | biological process | ATP1B2 |
| neuropeptide catabolic process | biological process | CTSH |
| neuropeptide processing | biological process | MME |
| neuropeptide signaling pathway | biological process | PROKR2, KISS1R, TAC3, PROK2, TAC1, GPR83, CYSLTR1, RAPGEF2, NXPH3, MC2R, QRFP, PTH2, GRP, PRLHR, HCRTR1, NPY, SCG5, NTS, QRFPR, GLRA3, PMCH, NMU, MCHR2, UCN, MCHR1, SORCS3, NPFFR2, LTB4R, OPRD1, SORCS2, SORT1, NPFF, NPY1R, NPBWR1, SORL1, PDYN, PROKR1, NMUR2, NMUR1, UTS2R, PTGDR2, ECEL1, CALCA, NMB, GLRA1, CARTPT, NPB, CPE, SSTR4, HCRT, SSTR3, NTSR2, GALR1, RXFP4, SORCS1, ECRG4, GPR84, GAL, LTB4R2, POMC, NTSR1, OPRL1, GALR3, NXPH4, SSTR5, NPBWR2, GPR143, CRCP, PYY, GPR1, GLRA2, OPRK1, NXPH2, PENK, TYRO3, NPY5R, GPR139, GALP |
| neuropilin signaling pathway | biological process | ABL1, NRP1 |
| neurotransmitter biosynthetic process | biological process | PAH, SLC22A2, ALDH9A1, GAD1, SLC6A4, TH, DAGLB, SLC5A7, CHAT, SLC6A3, DAGLA, GAD2 |
| neurotransmitter catabolic process | biological process | COMT, NAALAD2, ABAT, LRTOMT, ALDH5A1, PRIMA1 |
| neurotransmitter loading into synaptic vesicle | biological process | SLC17A6, SLC18A2, SLC32A1, SLC17A7 |
| neurotransmitter metabolic process | biological process | CLN3 |
| neurotransmitter receptor cycle | biological process | NSG1 |
| neurotransmitter receptor internalization | biological process | CACNG2, CACNG3, SNAP25, AP2B1, CACNG4, CACNG8 |
| neurotransmitter receptor localization to postsynaptic specialization membrane | biological process | LGI1, CACNG2, CACNG3, CACNG7, DLG1, ADAM22, DLG4, DLG2 |
| neurotransmitter receptor metabolic process | biological process | NRG1, FNTA |
| neurotransmitter receptor transport postsynaptic membrane to endosome | biological process | LRRC1, SCRIB |
| neurotransmitter receptor transport to postsynaptic membrane | biological process | CLSTN1, RAB8A, MAPK10 |
| neurotransmitter receptor transport, endosome to plasma membrane | biological process | VPS35 |
| neurotransmitter receptor transport, endosome to postsynaptic membrane | biological process | RAB11A, GRIPAP1, LRRC1, SCRIB, GRIP1, RAB8A, NSG1, GRIP2, ARHGAP44, VPS35 |
| neurotransmitter receptor transport, postsynaptic endosome to lysosome | biological process | CACNG2, AP3D1, CACNG3, CACNG4, CACNG8 |
| neurotransmitter reuptake | biological process | SLC6A2, SLC1A2, SLC6A11, SLC29A2, SLC6A4, SLC1A7, SLC29A1 |
| neurotransmitter secretion | biological process | HSPA8, PPFIA1, GRM4, SLC22A2, PPT1, RIMS1, LIN7C, DVL1, SNAPIN, CPLX1, PPFIA2, LIN7A, SYT1, SLC18A3, SNPH, DGKI, NRXN2, SYN1, GAD1, SNAP25, PTPRN2, UNC13B, DNAJC5, STXBP3, NAAA, APBA1, SYN2, CASK, PPFIA3, SLC5A7, HRH3, CHAT, SLC18A2, UNC13A, SYN3, PPFIA4, CACNA1B, STXBP2, SYT2, BRSK1, SLC32A1, WNT7A, GAD2, LIN7B |
| neurotransmitter transport | biological process | SLC6A14, SLC6A20, SLC6A8, SYNJ1, SLC28A2, SLC6A6, SLC22A2, SLC6A2, GABRA2, RIMS1, STX3, CPLX1, SLC18A3, SLC6A15, STX1B, SLC6A11, SLC6A16, SLC17A6, SLC29A2, SV2C, SLC6A4, ICA1, SLC6A12, STX4, SV2B, SLC6A7, SLC6A9, RIMS3, SLC18A2, SLC29A1, GABRQ, SLC6A5, SLC6A18, SLC6A3, SV2A, SLC32A1, SLC6A13, SLC22A1, SLC22A3, CPLX2, CPLX3, RIMS4, SLC17A7, SLC6A17 |
| neurotransmitter uptake | biological process | SLC38A1, SLC1A3, GLUL, SLC6A11, SNAP25, ATP1A2, SLC29A2, SLC1A6, SLC1A7, SLC6A9, SLC29A1, SLC6A5, SYNGR3, SLC6A3 |
| neurotrophin TRK receptor signaling pathway | biological process | CASP3, SRC, NGF, RAF1, PTPN11, SOS1, NTRK1, NDN, NTF4, BCAR1, NTRK2, GRB2, FRS2, SORT1, NGFR, AKT1S1, HAP1 |
| neutral amino acid transport | biological process | SLC7A5, SLC38A9, SLC1A5, SLC38A7, SLC36A1, SLC38A1, SLC6A15, SLC7A8, SLC38A2, SLC7A9, SLC43A1, SLC6A19, SLC7A10, SLC43A2, SLC6A17 |
| neutrophil activation | biological process | CXCL8, CCL5, IL15, CXCL6, IL18RAP, CXCR2, PRKCD, KMT2E, FCAR, PREX1 |
| neutrophil activation involved in immune response | biological process | SYK, TYROBP, LILRA2, FCER1G, DNASE1L3, DNASE1 |
| neutrophil aggregation | biological process | S100A9, S100A8 |
| neutrophil apoptotic process | biological process | IFNG, IL6, HCAR2 |
| neutrophil chemotaxis | biological process | IFNG, IL1B, CXCL8, S100A12, CCL5, S100A9, SAA1, CX3CL1, CCL16, CCL20, CCL8, CSF3R, CXCL11, CCL1, CCL14, VAV3, CCL3, SYK, CCL11, CXCL6, CKLF, CCL22, PF4, CXCR2, TGFB2, PDE4B, CXCL2, CCL26, SRP54, CXADR, PDE4D, PLA2G1B, S100A8, CXCL1, CCL18, PIK3CG, CCL23, CCL19, ITGB2, CCL3L1, CXCR1, FCER1G, NCKAP1L, ITGA9, PREX1, PIK3CD, PPBP, EDN1, CXCL3, CCL7, JAML, GBF1, PF4V1, VAV1, PIP5K1C, EDN3, DPEP1, CCL17, CCL21, CXCL10, CCL2, C5AR1, CXCL5, CCL15 |
| neutrophil clearance | biological process | ANXA1, HMGB1, MERTK |
| neutrophil degranulation | biological process | NDUFC2, FUCA1, LTA4H, HSPA8, PSMB1, SLC2A5, PSMC2, EEF1A1, RAB18, ACTR10, LAMTOR3, HPSE, DERA, CAB39, ATP6V1D, SIRPB1, DDX3X, SLC2A3, PSMA2, PSMA5, GLIPR1, COTL1, MLEC, PSMB7, METTL7A, SURF4, ATP6AP2, FTL, GLA, CD55, XRCC5, IQGAP1, GYG1, ACLY, RAP2B, OLR1, IQGAP2, PSMD6, ORMDL3, SLC15A4, ATP8B4, PSMD1, DSN1, SNAP23, PSMD14, SYNGR1, CPNE3, CFD, GDI2, RAB27A, PSMD7, COPB1, CCT2, CD47, BST2, ATAD3B, HUWE1, ARMC8, FAF2, MGAM, CYBB, CTSB, SERPINB6, PLD1, GOLGA7, CNN2, CD93, PLAC8, COMMD3, AGPAT2, ARPC5, CSTB, ANXA3, CD58, CAMP, CTSC, TNFAIP6, FABP5, ILF2, ANO6, ARHGAP9, VAMP8, ORM1, FTH1, GUSB, APEH, CD59, RAB6A, PGM1, SRP14, MNDA, PGRMC1, PNP, ACAA1, PKM, CD53, PTPN6, CHI3L1, RAB31, ARHGAP45, HVCN1, QSOX1, TOM1, STK10, TMEM63A, AP2A2, PSAP, RNASE2, EEF2, PSMC3, STOM, PRDX6, PRCP, IST1, RHOG, ABCA13, CLEC4C, GGH, SNAP29, ITGAM, EPX, XRCC6, LAMP2, CYBA, SERPINB1, CEACAM8, AGL, UBR4, HGSNAT, TBC1D10C, MCEMP1, PADI2, HEBP2, MANBA, DIAPH1, CTSG, CD63, TCN1, CKAP4, ROCK1, OSTF1, PTGES2, DBNL, PIGR, ALDOA, APRT, PTPRC, |
| neutrophil differentiation | biological process | LBR, DHRS7B, FASN, LEF1 |
| neutrophil extravasation | biological process | PIK3CG, PIK3CD, JAML, PECAM1, PRTN3 |
| neutrophil homeostasis | biological process | MTHFD1, SH2B3, JAM3, ANXA1, PDE4B, MPL |
| neutrophil mediated immunity | biological process | IL6, IL6R, ACE, WDR1, PLA2G1B, KMT2E, FCAR, IRAK4 |
| neutrophil mediated killing of fungus | biological process | ELANE |
| neutrophil migration | biological process | WDR1, UMOD, GP2, ITGB2, MCOLN2, IRAK4 |
| neutrophil-mediated killing of bacterium | biological process | AZU1 |
| neutrophil-mediated killing of gram-negative bacterium | biological process | TUSC2, F2 |
| neutrophil-mediated killing of gram-positive bacterium | biological process | CTSG |
| nicotinamide metabolic process | biological process | PTGS2, APOA1BP |
| nicotinamide nucleotide metabolic process | biological process | NAXD |
| nicotinamide riboside catabolic process | biological process | PNP, MTAP |
| nicotinate transport | biological process | SLC22A13 |
| NIK/NF-kappaB signaling | biological process | PSMA3, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, PSMD14, PSMD7, ALK, BTRC, PSMB6, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, CUL1, PSMB8, PSMD4, PSMC3, PSMA6, RELA, IKBKE, NFKB2, REL, BIRC2, PSMD12, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, PSMD5, PSMF1, PSMB3, PPP4C, MAP3K14, RIPK3, PSMD3, PSMC1, RELB, PSMD13, PSMB10 |
| nitrate catabolic process | biological process | POR |
| nitrate metabolic process | biological process | MTARC2, THAP4, MTARC1 |
| nitrate transport | biological process | AQP6 |
| nitric oxide biosynthetic process | biological process | NOS3, AKT1, NOS2, CYP1B1, ARG2, NQO1, SPR, RORA, DDAH2, GCH1, SLC7A2 |
| nitric oxide catabolic process | biological process | POR |
| nitric oxide homeostasis | biological process | ADNP, CAV1 |
| nitric oxide mediated signal transduction | biological process | APOE, NOS3, FPR1, NOS2, DDAH1, PDX1, GUCY1B1, GUCY1A1, NEUROD1, DDAH2, MT1M, AGT, NDNF, CD36 |
| nitric oxide metabolic process | biological process | CPS1, TLR6 |
| nitric oxide production involved in inflammatory response | biological process | TLR4, SLC7A2 |
| nitric oxide storage | biological process | GSTP1 |
| nitric oxide transport | biological process | HBB, AQP1, EDN1 |
| nitric oxide-cGMP-mediated signaling pathway | biological process | GUCY1B1, KCNC2 |
| nitrite transport | biological process | SLC11A1 |
| nitrobenzene metabolic process | biological process | GSTM1, GSTM4 |
| nitrogen catabolite activation of transcription from RNA polymerase II promoter | biological process | NR1H4 |
| nitrogen compound metabolic process | biological process | PKD1, SEC63, CPS1, NADSYN1, ARID5B, TIPARP, NIT1, BTD, UPB1, GLUL, VNN2, VNN1, VNN3, PDGFRB, CAD |
| NK T cell differentiation | biological process | PSAP, ITK, ZBTB7B |
| NK T cell proliferation | biological process | IL15, ELF4 |
| NLRP1 inflammasome complex assembly | biological process | NLRP1 |
| NLRP3 inflammasome complex assembly | biological process | NLRP3, AIM2 |
| NLS-bearing protein import into nucleus | biological process | KPNA4, KPNA2, RGPD4, KPNA5, NUP35, KPNA3, KPNA6, IPO5, RGPD2, KPNA1, NUP54, RANBP2, CBLB, RGPD1, RGPD8, RGPD5 |
| NMDA glutamate receptor clustering | biological process | APOE, NRXN1, RELN |
| NMDA selective glutamate receptor signaling pathway | biological process | TIAM1, SULT1A3 |
| nodal signaling pathway | biological process | NODAL, TDGF1, ACVR1B, ACVR1C, CFC1B, SMAD2, TGIF2, SMAD3 |
| nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological process | NODAL, CITED2, FOXH1 |
| non-canonical Wnt signaling pathway | biological process | RYK, FZD4, DVL1, WNT4, FZD7, VANGL2, DVL2, CCDC88C, WNT11, DVL3, FZD6, WNT7A |
| non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological process | WNT9B |
| non-canonical Wnt signaling pathway via JNK cascade | biological process | FZD7, DVL3, MYOC |
| non-canonical Wnt signaling pathway via MAPK cascade | biological process | WNT4 |
| non-motile cilium assembly | biological process | IFT88, PCM1, IFT57, IFT74, BBS2, TMEM17, IFT52, TOGARAM1, INTU, MKKS, DISC1, TTC8, PIBF1, BBS4, CSNK1D, ARL13B, GORAB, CEP89, TMEM107, C2CD3, VANGL2, TBC1D32, IFT80, EXOC5, CEP126, CCDC13, TMEM80, CEP250, IFT122, FUZ, BBS1, CC2D2A, IFT172, RPGRIP1L |
| non-recombinational repair | biological process | REXO4 |
| non-replicative transposition, DNA-mediated | biological process | PGBD5 |
| nonassociative learning | biological process | MAPK8IP2 |
| nonfunctional rRNA decay | biological process | PELO |
| nor-spermidine metabolic process | biological process | SAT2 |
| noradrenergic neuron development | biological process | PHOX2B, ASCL1, INSM1 |
| noradrenergic neuron differentiation | biological process | PHOX2B, SOX11, SOX4, PHOX2A, HAND2 |
| noradrenergic neuron fate commitment | biological process | ASCL1 |
| norepinephrine biosynthetic process | biological process | GATA3, INSM1, MOXD1, TH, DBH |
| norepinephrine metabolic process | biological process | AKR1B1, PRKN, ATP7A, EPAS1 |
| norepinephrine secretion | biological process | NISCH |
| norepinephrine transport | biological process | SLC6A2, SLC6A3, SLC22A1 |
| norepinephrine uptake | biological process | SLC22A2, SLC6A2, SLC6A3, SLC22A1, SLC22A3 |
| norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure | biological process | ADRA1A |
| norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure | biological process | ADRB2, ADRB3, ADRB1 |
| Norrin signaling pathway | biological process | NDP, FZD4, LRP5 |
| nose development | biological process | CHD7, ALDH1A3, SMCHD1, GNG8, RDH10, HESX1, RPGRIP1L |
| nose morphogenesis | biological process | GLI3, SKI, STRA6 |
| Notch receptor processing | biological process | APH1B, PSENEN, APH1A, PSEN1, GALNT11, PSEN2, DNER |
| Notch receptor processing, ligand-dependent | biological process | APH1B, PSENEN, APH1A, PSEN1, PSEN2 |
| Notch signaling involved in heart development | biological process | NOTCH1, RBPJ, HEY2, GALNT11, HEY1, JAG1 |
| Notch signaling pathway | biological process | TGFB1, SOX9, HNF1B, APP, IL2RA, TP63, MYC, ANXA4, ETV2, SPEN, MIB1, ITCH, IFT74, CFD, HOXD3, DTX3L, APH1B, FBXW7, PSENEN, RPS19, NEURL1, NOTCH2NLC, HES1, NOTCH2NLA, APH1A, FOXA1, CREBBP, WDR12, YBX1, NOTCH1, MDK, CNTN1, GMDS, DTX1, NKAP, NEUROD4, PSEN1, ASCL1, HES7, ANGPT4, SUSD5, PGAM2, ITGB1BP1, SORBS2, GOT1, CDK6, EP300, NR1H4, PLN, CDKN1B, RITA1, SEL1L, KRT19, RBPJ, FOXC2, SNW1, NRARP, MAML2, PERP, TMEM100, HEY2, EPN1, AGXT, CDH6, NOTCH4, NOTCH3, PTP4A3, GALNT11, TGFBR2, TIMP4, NLE1, BMP2, PSEN2, ZNF423, S1PR3, ONECUT1, HEY1, DLL1, FOXC1, MESP1, CHAC1, POFUT1, JAG2, DLK2, DTX2, KAT2B, DTX4, JAG1, MIB2, FCER2, DNER, GRIP2, NEURL1B, MAML1, IFT172, CNTN6, DTX3, MAML3, DLL3, TBX2 |
| Notch signaling pathway involved in arterial endothelial cell fate commitment | biological process | DLL1 |
| Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation | biological process | NOTCH1 |
| notochord cell development | biological process | EPHA2 |
| notochord development | biological process | SOX9, COBL, COL2A1, ID3, TEAD2, YAP1, STIL, GDF3 |
| notochord formation | biological process | EFNA1, EPHA2, CRB2 |
| notochord morphogenesis | biological process | WNT11, EPHA2 |
| notochord regression | biological process | GLI1, GLI2 |
| nuclear body organization | biological process | SF1 |
| nuclear DNA replication | biological process | ATAD5, ZNF830, DONSON |
| nuclear envelope disassembly | biological process | PLK1, AKAP8L |
| nuclear envelope organization | biological process | DMPK, NUP93, ZMPSTE24, LEMD2, NUP155, REEP4, TMEM170A, CTDNEP1, PARP11, SUN2, TMEM201, REEP3 |
| nuclear envelope reassembly | biological process | CHMP2A, UBXN2A, CHMP4B, NSFL1C, UBXN2B, CHMP7, SPAST |
| nuclear export | biological process | MALT1, NCBP2, HNRNPA1, NEMF, NCBP1, EIF4ENIF1, ATXN1, RITA1, AKAP13, LSG1, LZTS2 |
| nuclear fragmentation involved in apoptotic nuclear change | biological process | GPER1 |
| nuclear histone mRNA catabolic process | biological process | SSB |
| nuclear matrix anchoring at nuclear membrane | biological process | SUN2, SYNE1 |
| nuclear membrane organization | biological process | TOR1AIP1, TMEM43, TOR1B |
| nuclear migration | biological process | CDC42, MYH10, SLC9A3R1, PTK2, SLIT1, NTN1, CLMN, TBCB, SYNE2, SUN2, TMEM201, FHOD1 |
| nuclear migration along microfilament | biological process | SYNE2, SUN2 |
| nuclear migration along microtubule | biological process | ACTR10, ACTR1A, ACTR1B, TMEM201 |
| nuclear mRNA surveillance | biological process | EXOSC10, EXOSC9, EXOSC7, EXOSC5, DXO, XRN1, EXOSC8, EXOSC4, EXOSC6 |
| nuclear polyadenylation-dependent mRNA catabolic process | biological process | EXOSC9, EXOSC7, EXOSC8, PNPT1 |
| nuclear polyadenylation-dependent rRNA catabolic process | biological process | EXOSC10, EXOSC9, EXOSC7, EXOSC3, EXOSC8, EXOSC2 |
| nuclear polyadenylation-dependent tRNA catabolic process | biological process | EXOSC9, EXOSC7, EXOSC3, EXOSC8, EXOSC2 |
| nuclear pore complex assembly | biological process | NUP93, NUP107, RTN4, NUP205, NUP153, AHCTF1, TMEM170A, TPR, NUP98 |
| nuclear pore distribution | biological process | NUP133 |
| nuclear pore organization | biological process | NUP35, SEH1L, NUP133, NUP54, TPR, NUP98 |
| nuclear retention of pre-mRNA at the site of transcription | biological process | PCID2 |
| nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription | biological process | EXOSC3, EXOSC2 |
| nuclear retention of unspliced pre-mRNA at the site of transcription | biological process | EXOSC10, PRPF18 |
| nuclear speck organization | biological process | DYRK3, SRPK2, AFF2 |
| nuclear transport | biological process | PSIP1, NUP62, XPO7 |
| nuclear-transcribed mRNA catabolic process | biological process | EXOSC10, LSM1, LSM3, MRTO4, EXOSC9, XRN2, NBAS, UPF1, DXO, RC3H1, XRN1, NBDY, EXOSC4, AGO1, LSM7, THRAP3, DHX34, LSM4 |
| nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay | biological process | SKIV2L |
| nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | PAN3, CNOT1, POLR2D, PAN2, ZFP36L2, RC3H1, CNOT6L, ZFP36, ZFP36L1, DCPS |
| nuclear-transcribed mRNA catabolic process, deadenylation-independent decay | biological process | ZFP36, ZFP36L1 |
| nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay | biological process | ZC3H12A, UPF1 |
| nuclear-transcribed mRNA catabolic process, exonucleolytic | biological process | POLR2G, DIS3L2 |
| nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' | biological process | EXOSC9, EXOSC7, EXOSC5, EXOSC3, EXOSC8, EXOSC4, EXOSC6, EXOSC2, DIS3L2 |
| nuclear-transcribed mRNA catabolic process, no-go decay | biological process | CSDE1, PELO, GTPBP2 |
| nuclear-transcribed mRNA catabolic process, non-stop decay | biological process | PELO |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological process | PABPC1, EXOSC10, RPL4, RPL3, RPL5, RPS10, EIF3E, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, RPL24, RPL6, UPF2, RPLP0, GSPT1, RPL29, NCBP2, RPL15, RPS8, RPL7A, ETF1, RPL32, RPS21, RPL7, RPL13, RPS18, RPS13, RPL11, PPP2CA, RPL19, PARN, RPL35A, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, PPP2R2A, RPS2, RPL9, RPS19, RPS5, RPS25, RPL30, RPS27A, RPL38, RPS3, RPL13A, RPL35, DCP2, GSPT2, UPF3A, CASC3, RPLP1, RPS12, RPS27, RPL39, NCBP1, SMG8, HELZ2, PNRC2, RPS4Y1, RPL8, UPF1, DCP1B, PYM1, RBM8A, SMG7, RPL27A, RPL18A, SMG6, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, SMG1, RPL14, RPL37, RPS15A, RPS24, RPS28, RPL36, CTIF, RPL10, MAGOHB, UPF3B, RPLP2, RPS17, RPL23A, RPL18, UBA52, RPSA, DCP1A, RPS11, RPL36A, RPL17, RPL23, RPL26, SMG5, PPP2R1A, EIF4A3, DHX34 |
| nuclear-transcribed mRNA poly(A) tail shortening | biological process | PABPC1, MLH1, PAN3, CNOT1, CNOT4, CNOT8, PARN, PAN2, CNOT10, CNOT9, SAMD4A, CNOT6L, CNOT2, ZFP36, TUT4, CNOT3, SAMD4B, TUT7, TNKS1BP1 |
| nucleic acid phosphodiester bond hydrolysis | biological process | RAG1, POLG, PMS2, DROSHA, RNASET2, EXOSC10, MEIOB, ANKLE1, DDX1, RBBP8, REV3L, G3BP1, EXO5, FEN1, ASTE1, N4BP2, SLX1A, CNOT8, ENPP2, TATDN1, RNASE11, STK31, ERI2, APTX, REXO2, ENDOV, PLD4, MGME1, PELO, APEX2, REXO5, ATAD5, DCLRE1C, AGO3, PXDNL, ENPP3, PPP1R8, PAN2, EXO1, RNASEL, EXD1, TDP1, DXO, ENPP1, PGAP1, REXO1, EXD3, DCLRE1B, PRORP, RAD9B, SMG6, RAD9A, RAD1, YBEY, TSN, ZRANB3, DIS3, TDP2, PNPT1, GEN1, CNOT6L, RAD50, EXD2, RNASE3, USB1, RNASEH2A, DCLRE1A, POLE, MRPL44, TSEN15, TATDN2, TSEN2, ANG, ERN2, APLF, DIS3L2, HARBI1, TREX1, SND1, PLD3, EME2, ISG20L2, PGBD5, RNASE7 |
| nucleobase transport | biological process | SLC23A1, SLC23A2 |
| nucleobase-containing compound metabolic process | biological process | ERCC2, PRPS2, EXOSC10, POLR1H, SLC28A2, DPYSL2, SLC28A1, AK2, NUDT5, ATIC, SRBD1, REXO2, XRN2, PNP, CTPS1, AK4, NUDT2, UPP1, EXD1, DCK, EXD3, RTEL1, POLR3H, AK1, TPMT, DGUOK, AK9, DUT, CMPK1, AK3, PRPSAP1, AK8, EXD2, SLC23A1, ERH, AK7, BRIP1, TK2, FPGS, MTAP, DDX11, GDA, SLC29A1, CRMP1, SLC23A2, PRPSAP2, TK1, OAS2 |
| nucleobase-containing compound transport | biological process | TMEM241, SLC35D2, SLC35E3 |
| nucleobase-containing small molecule catabolic process | biological process | NUDT9, NUDT5, NUDT15, NUDT1, ENTPD5, NUDT16, ENTPD7, ENTPD4, ADPRM, ENTPD8, ENTPD2, ENTPD3 |
| nucleobase-containing small molecule interconversion | biological process | GSR, TYMS, AK2, TXNRD1, RRM2, AK6, RRM2B, GUK1, CTPS1, AK4, AK1, AK9, RRM1, DUT, CMPK1, NME2, AK8, NME3, AK7, GLRX, NME1, DCTD, NME4, DTYMK, CTPS2 |
| nucleocytoplasmic transport | biological process | NPM1, NUP88, ANP32A, NUP35, NUP58, XPO1, NUP205, EIF5A, UPF3A, NUP155, CITED1, NEUROD1, RSRC1, NXT1, RAN, FBXO22, NUP54, NXT2, NUP98, RBM15B, ANKRD54, NUTF2, CDK5, AAAS, RGS14, CAMK1 |
| nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration | biological process | SYNE2, SUN2 |
| nucleolar chromatin organization | biological process | DDX11 |
| nucleolar large rRNA transcription by RNA polymerase I | biological process | POLR1E, TAF1B, TCOF1 |
| nucleologenesis | biological process | POLR1B, EMG1 |
| nucleolus organization | biological process | RPS19, RRN3, USP36, PES1 |
| nucleoside diphosphate biosynthetic process | biological process | ENTPD8 |
| nucleoside diphosphate catabolic process | biological process | ENTPD3 |
| nucleoside diphosphate metabolic process | biological process | AK2 |
| nucleoside diphosphate phosphorylation | biological process | NME8, NME7, NME5, NME9, AK4, AK1, CMPK1, NME6, NME2, AK8, NME3, AK7, NME1, NME4, DTYMK |
| nucleoside metabolic process | biological process | PRPS1L1, NME5, ATIC, PNP, NT5C1A, DNPH1, PRPS1, UPP1, UCKL1, APRT, UPRT, HPRT1, PPAT, UMPS, MTAP, PRTFDC1, NME4, UPP2, PRPSAP2 |
| nucleoside monophosphate biosynthetic process | biological process | ENTPD8 |
| nucleoside monophosphate phosphorylation | biological process | AK2, AK6, AK4, AK1, CMPK1, AK3, RAD50, AK8, AK7, DTYMK |
| nucleoside phosphate catabolic process | biological process | NUDT15 |
| nucleoside phosphate metabolic process | biological process | NUDT5 |
| nucleoside transmembrane transport | biological process | SLC28A2, SLC28A1, SLC29A2, SLC29A1, SLC29A3, SLC28A3 |
| nucleoside transport | biological process | SLC28A1, SLC29A2, SLC29A1, SLC29A3 |
| nucleoside triphosphate biosynthetic process | biological process | AK4, AK1, CMPK1, AK3, NME2, AK8, AK7 |
| nucleoside triphosphate catabolic process | biological process | SMPDL3A, ITPA, DCTPP1, ENPP3, ENPP1, ENTPD3 |
| nucleosome assembly | biological process | BRD2, SOX9, TSPY1, H2AFX, H2BFWT, TSPYL1, HIST1H4A, H1-4, NASP, NPM1, NAP1L1, SMARCA5, ANP32B, RSF1, ATRX, H2BC21, NAP1L4, TSPYL2, MACROH2A2, H2BC5, SART3, TSPYL5, H2BC12, SPTY2D1, H1-2, H2BC3, H1-8, NAP1L3, TSPY3, TSPY10, HP1BP3, MACROH2A1, TSPYL6, H1-0, H2AB1, H2BU1, H2BC9, GRWD1, NAP1L2, H1-5, H2BC17, NAP1L5, H1-1, H4C7, H2BC15, H1-3, SET, KAT6A, PADI4, H3C1, CHAF1A, TSPYL4, MCM2, KAT6B, NAA60, TSPY4, H3-3A, ASF1B, H2BW2, H2AB2, H4-16, H2BC10, H3C13 |
| nucleosome disassembly | biological process | TNP1, ARID2, SUPT16H, SMARCA4, SMARCE1, SMARCD3, SMARCB1, SMARCC2, PBRM1, ARID1A, SMARCC1, GRWD1, NFE2, SET, SMARCD1 |
| nucleosome mobilization | biological process | POLE3, BPTF, ARID1A, INO80 |
| nucleosome organization | biological process | MCM3AP |
| nucleosome positioning | biological process | H1-4, SMARCA5, RSF1, PAF1, H1-2, H1-8, SMARCA1, H1-0, H1-5, H1-1, H1-3 |
| nucleotide biosynthetic process | biological process | PRPS2, PRPS1L1, NMNAT1, TYMS, ME1, NMNAT3, PNP, PRPS1, PRPSAP1, TK2, DCTD, DTYMK, NMNAT2, PRPSAP2 |
| nucleotide catabolic process | biological process | NT5E, UPP1, UPP2 |
| nucleotide metabolic process | biological process | ACPP, NME7, GMPR2, NUDT5, NT5C3B, REXO2, NT5C1A, ITPA, AMPD2, NT5C, DNPH1, FHIT, NUDT16, AK9, ADAL, DUT, NT5C1B, NME6, ADA, NME2, AMPD3, PUDP, NME3, GMPR, NME1, NT5C2, NME4, NT5M |
| nucleotide phosphorylation | biological process | GUK1 |
| nucleotide transmembrane transport | biological process | SLC25A17 |
| nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway | biological process | RNF34 |
| nucleotide-binding oligomerization domain containing 1 signaling pathway | biological process | NFKBIA, RIPK2 |
| nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | LACC1, NOD2, RELA, OTULIN, NFKBIA, RIPK2, IRGM, INAVA |
| nucleotide-binding oligomerization domain containing signaling pathway | biological process | CASP8, ITCH, MAP3K7, IRAK1, UBE2N, RPS27A, IRAK2, TAB1, NOD2, IKBKG, UBE2V1, CYLD, TAB2, RIPK2, TRAF6, UBC, UBA52, TAB3, MAP2K6, UBB, NOD1 |
| nucleotide-excision repair | biological process | TP53, BRCA2, OGG1, ERCC1, ERCC2, XPA, RAD23A, RAD23B, XPC, GTF2H3, FAN1, CETN2, SLC30A9, NEIL1, RPA2, CETN1, DDB2, RPA1, SLX4, ERCC5, ERCC8, NEIL2, ATXN3, COMMD1, GTF2H1, HUS1, RPA3, ERCC4, FANCC, HUS1B, GTF2H4, STN1, MMS19, BRIP1, MNAT1, NEIL3, POLL, DDB1, POLA1, GTF2H5 |
| nucleotide-excision repair involved in interstrand cross-link repair | biological process | XPA, ERCC4 |
| nucleotide-excision repair, DNA damage recognition | biological process | XPA, PARP1, RAD23B, XPC, COPS5, CETN2, COPS8, COPS6, RPS27A, DDB2, COPS4, COPS2, UBC, UBA52, RBX1, COPS7B, GPS1, COPS7A, UBB, DDB1 |
| nucleotide-excision repair, DNA duplex unwinding | biological process | ERCC2, XPA, PARP1, RAD23B, XPC, GTF2H3, CETN2, RPS27A, CHD1L, DDB2, GTF2H1, UBC, UBA52, GTF2H4, RBX1, UBB, DDB1, GTF2H5 |
| nucleotide-excision repair, DNA gap filling | biological process | LIG4, XRCC1, PCNA, RPA2, RFC4, RFC5, RFC3, RPS27A, RPA1, POLK, POLD2, UBC, RPA3, UBA52, LIG1, RFC2, LIG3, POLE, POLD4, POLB, UBB, POLD1, RFC1 |
| nucleotide-excision repair, DNA incision | biological process | OGG1, ERCC1, ERCC2, XPA, PARP1, PCNA, GTF2H3, FAN1, RPA2, RFC4, RFC5, RFC3, RPS27A, CHD1L, DDB2, RPA1, POLK, ERCC5, GTF2H1, POLD2, UBC, RPA3, UBA52, ERCC4, RFC2, GTF2H4, RBX1, POLD4, UBB, POLD1, RFC1, DDB1, GTF2H5 |
| nucleotide-excision repair, DNA incision, 3'-to lesion | biological process | ERCC1, ERCC2, XPA, PARP1, GTF2H3, RPA2, CHD1L, DDB2, RPA1, ERCC5, GTF2H1, RPA3, ERCC4, GTF2H4, RBX1, BIVM, DDB1, GTF2H5 |
| nucleotide-excision repair, DNA incision, 5'-to lesion | biological process | ERCC1, ERCC2, XPA, PARP1, PCNA, GTF2H3, RPA2, RFC4, RFC5, RFC3, RPS27A, CHD1L, DDB2, RPA1, POLK, ERCC5, NTHL1, GTF2H1, POLD2, UBC, RPA3, UBA52, ERCC4, RFC2, GTF2H4, RBX1, POLD4, UBB, POLD1, RFC1, DDB1, GTF2H5 |
| nucleotide-excision repair, preincision complex assembly | biological process | ERCC2, XPA, PARP1, RAD23B, XPC, GTF2H3, CETN2, RPA2, CDK7, CCNH, RPS27A, CHD1L, DDB2, RPA1, ERCC5, GTF2H1, UBC, RPA3, UBA52, GTF2H4, RBX1, MNAT1, UBB, DDB1, GTF2H5 |
| nucleotide-excision repair, preincision complex stabilization | biological process | ERCC1, ERCC2, XPA, PARP1, GTF2H3, RPA2, CHD1L, DDB2, RPA1, ERCC5, GTF2H1, RPA3, ERCC4, GTF2H4, RBX1, DDB1, GTF2H5 |
| nucleotide-sugar biosynthetic process | biological process | TSTA3 |
| nucleotide-sugar metabolic process | biological process | PARG |
| nucleus accumbens development | biological process | ALDH1A3 |
| nucleus localization | biological process | CDC42, CAV3, CLMN, KIF25, BIN1 |
| nucleus organization | biological process | PRM1, PRM2, PITPNB, CHMP2A, CEP55, CHMP5, VPS4B, ZMPSTE24, WDR73, CHMP4A, GOLM1, CHMP4B, CHMP1A, CHMP6, LEMD3, NUMA1, PDCD6IP, CHMP4C, CHMP7, IRAG2, SYNE1, ATXN7, BIN1, CHMP3, H3-3A, CHMP1B |
| O-glycan processing | biological process | MUC1, MUC13, MUC5B, MUC16, ST6GAL1, GALNT2, MUC6, ST6GALNAC4, GALNT13, GALNT5, GXYLT1, MUC21, MUC15, GALNT4, ST6GALNAC2, GALNT10, GALNT15, C1GALT1C1, GCNT1, B3GNT5, GALNT1, MUC7, MUC4, C1GALT1, B4GALT5, CHST4, GALNT8, ST3GAL4, GALNT11, POMGNT1, MUC17, GALNT12, POFUT1, B3GNT3, B3GNT8, B3GNT4, MUC12, B3GNT6, MUC20, GALNT9, ST3GAL1, B3GNT7, ST3GAL2, GALNT7, XXYLT1, MUCL1 |
| O-glycan processing, core 1 | biological process | C1GALT1C1, C1GALT1 |
| O-glycan processing, core 3 | biological process | B3GNT6 |
| observational learning | biological process | NF1 |
| obsolete multicellular structure septum development | biological process | SHH |
| obsolete transformed cell apoptotic process | biological process | TNF, BAX |
| octopamine biosynthetic process | biological process | MOXD1, DBH |
| oculomotor nerve development | biological process | HES1 |
| oculomotor nerve formation | biological process | TFAP2A, PHOX2A |
| odontoblast differentiation | biological process | FAM20C |
| odontogenesis | biological process | INHBA, TGFB3, BGLAP, FGFR2, BMP4, AQP5, FGF8, SHH, CSF1, PAM, BCOR, WNT10A, MYO5A, MSX1, ID3, PHEX, SSUH2, COL1A2, ZNF22, TGFB2, TWIST1, CEMP1, AQP3, TUFT1, LAMB1, AQP1, AQP6, MSX2, AXIN2, TCIRG1, ACP4, SDC1, OSR2, PITX2 |
| odontogenesis of dentin-containing tooth | biological process | ADM, BAX, BMP7, CTNNB1, BMP4, ITGA6, SHH, NF2, TP63, CA2, GLI3, HDAC2, BCL2L11, CTNNA1, BMPR1A, ACVR2B, NKX2-3, MSX1, BCL11B, ODAM, LRP6, NFIC, SMO, AMBN, ANKRD11, SOSTDC1, TRAF6, TNC, LEF1, ROGDI, RUNX2, EDA, BMP2, EDAR, PDGFRA, FOXC1, JAG2, LAMA5, DLX1, LRP4, GLI2, SCN5A, WNT6, SCN10A, DLX2, FGF10, HAND2 |
| Okazaki fragment processing involved in mitotic DNA replication | biological process | LIG1 |
| olfactory behavior | biological process | CHD7, CFAP69, ATP6V1B1, UBR3, LMX1A, GJB4, SHANK1 |
| olfactory bulb axon guidance | biological process | BCL11B |
| olfactory bulb development | biological process | SEMA3A, CHD7, EXT1, EOMES, KIF14, SLIT1, SKI, CRTAC1, EFNA2, ID2, ARX, CSF1R, LHX2, DLX2, LRRK2, RPGRIP1L |
| olfactory bulb interneuron development | biological process | ROBO2, SALL3 |
| olfactory bulb interneuron differentiation | biological process | DLX5, SALL1 |
| olfactory bulb mitral cell layer development | biological process | SALL1 |
| olfactory cortex development | biological process | ATP1A2 |
| olfactory learning | biological process | GRIN1 |
| olfactory lobe development | biological process | SEMA7A |
| olfactory nerve development | biological process | CHD7, NTRK1, SALL1 |
| olfactory pit development | biological process | ALDH1A3, ASCL1, DLX5 |
| olfactory placode formation | biological process | SIX1, SIX4, PROX1 |
| oligodendrocyte apoptotic process | biological process | TP53, TNFRSF21 |
| oligodendrocyte cell fate commitment | biological process | ASCL1 |
| oligodendrocyte cell fate specification | biological process | SOX6 |
| oligodendrocyte development | biological process | TGFB1, GSTP1, CD9, SHH, KCNJ10, NKX2-2, HDAC11, WASF3, EIF2B3, EIF2B1, OLIG1, NSUN5, PRDM8, ASCL1, SOX11, LYN, EIF2B2, LPAR1, ID2, EIF2B5, MED12, HDAC10, TPPP, MYRF, EIF2B4, ZNF488 |
| oligodendrocyte differentiation | biological process | SOX9, SOX10, ERBB2, NRG1, SHH, EED, GLI3, SUZ12, OLIG1, NOTCH1, NTRK2, ASCL1, SLC8A3, CNP, BNIP3, CDKN2C, SOX6, BOK, TSPAN2, VTN, CDK5, TRPC4, PTPRZ1, TPPP, CSK, GPR17, MYRF, NKX2-1, DUSP10 |
| oligopeptide transmembrane transport | biological process | SLC15A4, CDH17 |
| oligopeptide transport | biological process | SLC15A4, SLC15A2, CDH17, SLC15A1 |
| oligosaccharide biosynthetic process | biological process | ST6GALNAC6, B3GALNT1, B3GALT2, FUT8, B3GALT1, B4GALT1, B3GALT5, ST3GAL4, MGAT2, FUT3, ST6GALNAC5, ST6GALNAC1, MPDU1, ST3GAL2 |
| oligosaccharide catabolic process | biological process | HEXB, MAN2B1, MANBA, CTBS, NEU1, MAN2C1, NEU4, MAN2B2, NEU2, GM2A |
| oligosaccharide metabolic process | biological process | MAN1B1, ST6GALNAC6, GLA, GAL3ST3, ST6GALNAC4, FUT5, ST8SIA2, ST8SIA4, ST6GAL2, NAGA, ST8SIA1, FUT3, ST6GALNAC5, ST3GAL6, ST8SIA5, ST6GALNAC3, ST8SIA3, GAL3ST4 |
| oligosaccharide-lipid intermediate biosynthetic process | biological process | ALG2, ALG8 |
| omega-hydroxylase P450 pathway | biological process | CYP1A1, CYP1A2, CYP1B1, CYP4A11, CYP2C8, CYP2C19, CYP4F2, CYP2C9 |
| oncogene-induced cell senescence | biological process | HMGA2 |
| oncosis | biological process | TMEM123 |
| oncostatin-M-mediated signaling pathway | biological process | IL6ST, LIFR, OSM, OSMR |
| one-carbon metabolic process | biological process | MTHFD1, CA2, MTHFD2, SHMT1, GNMT, MAT2B, DHFR2, MTHFD1L, AHCYL1, SFXN1, CA5A, CA9, CA13, CA14, SHMT2, CA8, DHFR, AHCY, MAT2A, MTHFD2L, CA10, CA12, SFXN3, ALDH1L1, CA11, CA3, CA7, FPGS, MAT1A, CA4, AHCYL2, CA1, ALDH1L2 |
| oocyte development | biological process | BCL2, AURKC, ATM, DMRT1, CTNNB1, STRA8, YBX2, WNT4, MEIOC, FIGLA, ZP3 |
| oocyte differentiation | biological process | SOHLH2, LGR5, KMT2B |
| oocyte growth | biological process | GDF9, KMT2D, FOXL2 |
| oocyte maturation | biological process | INSL3, BRCA2, RXFP2, CCNB1, DAZL, REC8, PABPC1L, DMC1, WASHC5, TRIP13, EREG, PDE3A, YTHDF2, TUBB8, TUT4, FOXO3, ANG, CDC25B, PTK2B, TUT7 |
| oogenesis | biological process | ERCC1, HEXB, PIWIL2, SPO11, SRC, MLH1, SOHLH1, STRA8, HORMAD1, TAF4B, SOHLH2, NANOS3, KASH5, DIAPH2, PAQR8, PTN, ASPM, TRIP13, PANX1, KMT2D, MDK, DDX20, YTHDF2, SIX6OS1, PAQR5, MARF1, SEBOX, FIGLA, FMN2, H3-3A, PAQR7, MCMDC2 |
| operant conditioning | biological process | TACR2, DRD1, AGT |
| opioid receptor signaling pathway | biological process | OGFR, OGFRL1, ADCY8, OPRD1, NPBWR1, SIGMAR1, OPRL1, NPBWR2, OPRK1 |
| opsonization | biological process | CRP, CD47, MBL2, SPON2, LBP |
| optic cup formation involved in camera-type eye development | biological process | ARID1A, WNT16 |
| optic cup morphogenesis involved in camera-type eye development | biological process | ALDH1A3 |
| optic cup structural organization | biological process | TFAP2A |
| optic nerve development | biological process | NKX2-2, TMEM126A, SLC25A46, NAV2, LPAR1, TCIRG1 |
| optic nerve morphogenesis | biological process | GLI3, EPHB2, EPHB1, CHRNB2 |
| optic nerve structural organization | biological process | KCNA2 |
| optic placode formation involved in camera-type eye formation | biological process | FRS2, PROX1 |
| optic vesicle morphogenesis | biological process | TFAP2A, SIX3 |
| optokinetic behavior | biological process | OPN4 |
| orbitofrontal cortex development | biological process | FGFR2, FGFR1, ARPC5, DRD2 |
| organ growth | biological process | BCL2, FGFR2, PTPN11, NLGN4X, ACVR2B, ADRA1A, SMAD2, DLL1, FGF10 |
| organ induction | biological process | FGFR1, BMP4, FGF8, GDNF, SPRY1, FRS2, SIX1, HOXC11, HOXA11, FGF1, FGF10 |
| organ or tissue specific immune response | biological process | TREX1 |
| organelle assembly | biological process | STX7 |
| organelle disassembly | biological process | DYRK3, KIF9 |
| organelle fission | biological process | DNM3, OPA1, MX1, MX2, DNM1 |
| organelle fusion | biological process | STX4, CYP26C1 |
| organelle localization | biological process | STX7, MISP |
| organelle organization | biological process | KIF3A, ATP2A2, RAB38, XBP1, HPS3, HPS4, DTNBP1, KIF4A, MUL1, KIF25, HPS5 |
| organelle transport along microtubule | biological process | CDC42, BORCS5, COPG1, ARHGAP21, COPG2, KIF3C |
| organic acid metabolic process | biological process | CYP17A1, CYP2J2, STAR, CYP2R1, CYP2A7, CYP2C8, CYP2A6, CYP2C19, CYP2C18, CYP2E1, CYP2D6, CYP2S1, CYP2D7, CYP2W1, FMO1, CYP2C9 |
| organic acid transmembrane transport | biological process | SLC13A3, SLC5A8, SLC5A12, SLC6A15, SLC6A9 |
| organic anion transport | biological process | SLC17A3, SLCO1B3, SLC22A12, SLC22A9, ABCC11, SLC22A24, SLC37A3, SLC22A7, SLCO1A2, SLCO2B1, ABCC5, SLC22A11, SLC22A3, SLCO1C1 |
| organic cation transport | biological process | SLC22A18, SLC22A2, SLC47A1, SLC18A3, SLC7A8, SLC22A16, SLC22A4, SLC22A1, SLC22A3 |
| organic substance metabolic process | biological process | PGM3, PGM2L1, PGM1, PGM5, PGM2 |
| organic substance transport | biological process | MFSD2A, SLC51B, MFSD12, MFSD2B |
| organonitrogen compound catabolic process | biological process | RIDA |
| organophosphate catabolic process | biological process | PON1 |
| organophosphate metabolic process | biological process | PHEX |
| ornithine biosynthetic process | biological process | ALDH18A1 |
| ornithine metabolic process | biological process | AZIN2, HNF4A |
| ornithine transport | biological process | SLC7A6, SLC7A1, SLC25A29 |
| orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis | biological process | CELSR1, VANGL2 |
| osmosensory signaling pathway | biological process | WNK3, OXSR1 |
| ossification | biological process | EGFR, BCL2, MMP9, SOX9, IGF2, BGLAP, BMP7, LTF, BMP4, ECM1, CSF1, COL11A1, ATP6V1B1, CCN2, COL5A2, FZD9, EXT1, DHX36, PTN, RPL38, PTH1R, SPP1, GPM6B, CBFB, TMEM38B, SUCO, SBNO2, COL2A1, RUNX1, SP3, FSTL3, OSTF1, STATH, BMP1, SMO, SMPD3, MINPP1, MMP16, GPLD1, MESD, BMP5, SLC26A2, RASSF2, TAPT1, MMP14, TWIST1, IFITM1, FOXC2, TWSG1, TRAF6, SORT1, CLEC3B, BMP6, LRRC17, EXT2, KAZALD1, ATP6V0A4, PDLIM7, FGF18, DLX5, RUNX2, MSX2, CDH11, TNFRSF11A, MGP, BMP2, MYOG, IGSF10, NPPC, FOXC1, TCIRG1, COMP, PPARGC1B, NPR2, IHH, GDF2, PAM16, THRA, SLC34A1, PKDCC, COL13A1, SMAD5, EIF2AK3 |
| ossification involved in bone maturation | biological process | DCHS1, RYR1, SEMA4D, XYLT1, PLXNB1, THBS3 |
| ossification involved in bone remodeling | biological process | TGFB1, TGFB3, PTN, CTHRC1, GDF5 |
| osteoblast development | biological process | ESR1, BGLAP, SHH, HDAC4, TNN, HOXA2, PTH1R, MEN1, LRP5, RUNX2, PTHLH, MSX2, LIMD1, CLEC5A, JUND, GLI2, LRP5L, SMAD3, SATB2 |
| osteoblast differentiation | biological process | HSD17B4, CYP24A1, BGLAP, AKT1, SEMA7A, TMSB4X, CAT, BMP4, GJA1, SOX2, FGF9, RBMX, CCN1, PSMC2, HNRNPU, GTPBP4, MRC2, ATP5F1B, HNRNPC, IARS1, LGR4, SYNCRIP, ADAR, CCL3, SPP1, DDX21, GPNMB, HIRA, TPM4, CBFB, WNT3A, MEF2C, RDH14, RRAS2, FHL2, RSPO2, ALYREF, SMO, FASN, RPS15, LOX, COL6A1, FBL, ID4, TWIST1, IFT80, MEF2D, RRBP1, JUNB, TNC, CLTC, CCDC47, BCAP29, LEF1, DHH, SNRNP200, BMP6, LRRC17, SIRT7, WNT11, GLI1, DLX5, RUNX2, CHRD, EPHA2, MSX2, BMP2, WWTR1, IGFBP5, HSPE1, FIGNL1, SP7, MYBBP1A, ALPL, GLI2, IHH, SND1, GLIS1, GDF2, RSL1D1, CCN4, NF1, SMAD3, WWOX, ITGA11, H3-3A, MYOC, PENK |
| osteoblast fate commitment | biological process | RUNX2, SH3PXD2B, SMAD5 |
| osteoblast proliferation | biological process | MUS81, IFT80, JUNB, LRRC17, FIGNL1, OSR2 |
| osteoclast development | biological process | SRC, ANXA2, FOXP1, LRRK1 |
| osteoclast differentiation | biological process | TNF, CTNNB1, CSF1, MAPK14, GLO1, GPR183, SNX10, TFRC, IREB2, SBNO2, FOXP1, MITF, OSTM1, GAB2, TYROBP, TRAF6, EFNA2, JUNB, OSCAR, TREM2, FARP2, EPHA2, FCER1G, TNFRSF11A, TCIRG1, GPC3, CSF1R, DCSTAMP, CCN4 |
| osteoclast fusion | biological process | CD81, TCTA, SBNO2, CD109, SH3PXD2A, DCSTAMP |
| osteoclast maturation | biological process | FAM20C |
| osteoclast proliferation | biological process | CSF1, NPR3, TCIRG1 |
| otic placode development | biological process | NRP1 |
| otic placode formation | biological process | PROX1 |
| otic vesicle development | biological process | SOX9, GET1, AHI1, COL2A1, GATA3, PAX8, SIX1, EYA1 |
| otic vesicle formation | biological process | SOX9, FGFR2, FGF8, TCAP, CEP290, HESX1, FGF10 |
| otic vesicle morphogenesis | biological process | EYA1 |
| otolith development | biological process | ATG5 |
| otolith formation | biological process | SLC44A4 |
| otolith morphogenesis | biological process | TTC39C, LRIG3, LRIG1 |
| outer dynein arm assembly | biological process | CCDC103, DNAH5, DNAI1, ARMC4, LRRC6, DNAAF1, DNAH17, LRRC49, CCDC63, DNAAF4, DNAL1, ZMYND10, DNAI2, DNAH8, CCDC114, DNAAF5 |
| outer ear morphogenesis | biological process | MAPK3, MAPK1, FGFR1, PRKRA, TWIST1, EYA1, SALL1 |
| outer medullary collecting duct development | biological process | WNT7B |
| outer mitochondrial membrane organization | biological process | BAX |
| outflow tract morphogenesis | biological process | VEGFA, HIF1A, FGF8, ISL1, DHRS3, CLDN5, SOX18, HES1, RYR1, BMPR1A, FZD2, NOTCH1, MEF2C, NEDD4, SOX11, NIPBL, SEC24B, DVL2, RBPJ, ATF2, NPY1R, CITED2, HEY2, TBX3, SIX1, TBX20, WNT11, GJA5, ILK, SFRP2, MSX2, TGFBR2, EYA1, SEMA3C, ELN, NKX2-5, PLXND1, FZD1, ZFPM1, FOXH1, CRKL, TBX2, NPY5R |
| outflow tract septum morphogenesis | biological process | FGFR2, FGF8, ZFPM2, ISL1, RARB, SMAD4, ACVR1, BMPR1A, ROBO2, SMAD6, NRP2, TGFB2, LRP2, PARVA, TBX20, MSX2, TGFBR2, SEMA3C, ENG, NRP1, NKX2-5, ROBO1, RARA, TBX2 |
| ovarian cumulus expansion | biological process | EREG |
| ovarian follicle atresia | biological process | FAS, HYAL3 |
| ovarian follicle development | biological process | SOD1, FSHB, ICAM1, INHBA, BCL2, VEGFA, KITLG, AHR, BAX, ESR2, SPO11, MSH4, BMP15, KIT, BMP4, SOHLH1, STRA8, INHA, UBE3A, DMC1, SMAD4, CTNNA1, FANCG, ZNF830, PCYT1B, MMP14, IMMP2L, TAF4, EIF2B2, BCL2L1, EIF2B5, MMP19, VGF, FOXC1, ANG, FOXL2, LFNG, KMT2B, EIF2B4 |
| ovarian follicle rupture | biological process | NRIP1 |
| oviduct development | biological process | CTNNB1, LHX1, WNT7A |
| oviduct epithelium development | biological process | LHX1 |
| ovulation | biological process | IL1B, PTGS2, NRIP1, CYP17A1, ADAMTS1, TNFAIP6, HPGD, EREG, RGS2, IMMP2L, GAS2, KMT2B, IL4R |
| ovulation cycle | biological process | FAS, AXL, GNRH1, GABRB1, NHLH2, TIMP4, SERPINF1, TYRO3 |
| ovulation cycle process | biological process | LHCGR, PAM, MAP2K6, MSTN |
| ovulation from ovarian follicle | biological process | NOS3, LEP, ADAMTS1, MMP19, FOXO3 |
| oxalate metabolic process | biological process | HOGA1 |
| oxalate transport | biological process | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC26A2, SLC26A1, SLC26A10, SLC26A6 |
| oxalic acid secretion | biological process | AGXT, SLC26A6 |
| oxaloacetate metabolic process | biological process | MDH2, ACLY, MDH1, GOT1, MDH1B, GOT2 |
| oxaloacetate transport | biological process | SLC25A10 |
| oxaloacetate(2-) transmembrane transport | biological process | SLC25A10 |
| oxidation-dependent protein catabolic process | biological process | LONP1 |
| oxidation-reduction process | biological process | SOD1, CYP1A1, CYP19A1, HSD17B1, PTGS1, NOS3, SRD5A2, PTGS2, HSD17B4, PLOD1, CYP24A1, SOD2, CYP17A1, CYP1A2, HMOX1, MTHFD1, CYP2B6, HSD17B3, MTHFR, MTRR, GSR, GAPDH, CYP11A1, GPX1, MGST1, HSD3B1, CYP11B1, SRD5A1, HSD3B2, CBS, GPX4, HSD17B2, AKR1C3, PRDX4, DECR1, GSTK1, CAT, LPO, PDIA3, NOS2, XDH, PPOX, CYCS, TXNDC8, GAPDHS, IDH1, LDHC, CYP21A2, G6PD, CYP11B2, APEX1, PRDX2, CYP1B1, TXNDC2, CYP26B1, ALDH1A2, CYB5A, MT-CO1, KDM5C, PRDX1, KDM5D, MT-CYB, LDHA, MT-ND4, DAO, SDHB, SDHA, HIBADH, DCXR, NOX5, SCD, SELENOF, NDUFC2, TXNDC12, GLUD1, MT-ND5, LDHB, ACADM, AKR1B1, PAM, HAAO, NDUFA6, KCNAB1, LBR, PTGR1, GLRX5, P3H3, DOHH, KDM5B, NDUFB9, NDUFA4, NDUFB5, NDUFS6, NDUFB6, PAH, LIPF, ADH4, ADH5, MTHFD2, BCKDHB, GLDC, UQCRFS1, CYP2J2, FXN, ASPHD2, IDO2, LACC1, DNAJC10, CYB561D1, SCCPDH, HSPBAP1, GFOD1, HIGD1A, NOX1, PIR, CYB5B, PDHA1, UQCRB, MDH2, HCCS, SESN3, CYP4A11, CYP4F3, DHRS2, ETFDH, HADH, TXNRD1, ACAD11, MSRB3, GMPR2, GRHPR, PCYOX1, MSRA, DHRS7, MGST3, NDUFC1, AOC2, DHRS3, VCAM1, UQCRC2, RRM2, MDH1, ALDH9A1, |
| oxidative deethylation | biological process | CYP1A2 |
| oxidative demethylation | biological process | CYP1A2, CYP2C8, TET3, CYP3A5, TET1, ALKBH4, ALKBH1, TET2, CYP2D6, CYP2C9, CYP3A43 |
| oxidative DNA demethylation | biological process | TDG, ALKBH4, ALKBH1 |
| oxidative phosphorylation | biological process | MT-CO1, MSH2, ATP5F1C, COX7C, FXN, UQCRB, COX5A, UQCRC2, COX7B2, COX7A2, COX7B, COX6A1, ATP5F1D, COX6C, TEFM, NIPSNAP2, COX5B, COX6B1, COX8A, COX4I1, SURF1, UQCRC1, UQCRH, COX6A2, COX8C, COX7A1, CHCHD10, COX6B2 |
| oxidative RNA demethylation | biological process | ALKBH1 |
| oxidative single-stranded DNA demethylation | biological process | ALKBH3 |
| oxidative single-stranded RNA demethylation | biological process | ALKBH3, ALKBH5 |
| oxidative stress-induced premature senescence | biological process | TP53, PLA2R1, ARNTL, WNT16 |
| oxidised low-density lipoprotein particle clearance | biological process | CD36 |
| oxygen homeostasis | biological process | HIF1A, SOD2, AQP11, WNT7B, NNT, EGLN1, CIAO3 |
| oxygen metabolic process | biological process | NOX1, ME3 |
| oxygen transport | biological process | MYC, IPCEF1, HBG2, HBD, HBB, HBZ, MB, HBQ1, NGB, HBA1, CYGB |
| oxylipin biosynthetic process | biological process | CYP4A11, CYP4F11 |
| p38MAPK cascade | biological process | MAPK14, LGALS9, MAP2K3, MAP3K5, ZFP36, ZFP36L1 |
| palate development | biological process | INHBA, TGFB3, TGFBR3, SUMO1, SOS1, SHH, CHD7, PYGO2, GLI3, DHRS3, ANP32B, BCOR, CPLANE1, CLDN5, EPHB2, PLEKHA1, INTU, COL11A2, BMPR1A, ARID5B, WNT9B, COL2A1, ACVR2B, GDF11, SKI, MSX1, GABRB3, MEF2C, TIPARP, IRF6, LRP6, PRRX1, TFAP2A, FRAS1, TWIST1, DLX6, CSRNP1, TGFBR1, INSIG1, ASPH, PAK1IP1, TBX3, ALX4, WNT11, DLX5, WFIKKN2, LOXL3, FOXF2, NPRL3, WFIKKN1, FOXE1, PDGFRA, MEOX2, PRDM16, EPHB3, PKDCC, IFT172, SATB2, OSR2, HAND2, TBX2, ALX1, INSIG2 |
| pallium cell proliferation in forebrain | biological process | IGF2BP1 |
| pallium development | biological process | FGF8, GLI3 |
| palmitic acid biosynthetic process | biological process | ACOT7 |
| pancreas development | biological process | CTNNB1, SHH, ALDH1A2, TCF7L2, ISL1, HES1, NKX3-2, ACVR2B, GDF11, SELENOT, PDX1, ONECUT2, ILDR2, SMAD2, MEIS2, FOXF1, ONECUT1, MSLN, PROX1, IHH, FGF10, PTF1A |
| pancreas morphogenesis | biological process | NR5A2, SMO |
| pancreatic A cell differentiation | biological process | INSM1, RFX6 |
| pancreatic A cell fate commitment | biological process | NKX2-2, NEUROD1 |
| pancreatic D cell differentiation | biological process | RFX6 |
| pancreatic epsilon cell differentiation | biological process | RFX6 |
| pancreatic juice secretion | biological process | AQP5, NPR3, UCN, COPA, AQP1, SCT |
| pancreatic PP cell fate commitment | biological process | NKX2-2, NEUROD1 |
| pantothenate metabolic process | biological process | PANK2, VNN2, VNN1, VNN3, SLC5A6 |
| pantothenate transmembrane transport | biological process | SLC5A6 |
| paracrine signaling | biological process | PDGFB, CD34, SERPINB3, CGAS, FGF2 |
| parallel actin filament bundle assembly | biological process | USH1C, ESPN, FSCN1, AIF1 |
| paramesonephric duct development | biological process | WNT4, LHX1, GREB1L, STRA6 |
| paranodal junction assembly | biological process | CD9, EPB41L3, GNPAT, ANK2, NFASC, CNTNAP1, UGT8 |
| paranodal junction maintenance | biological process | WHRN |
| parasympathetic nervous system development | biological process | PHOX2B, PHOX2A |
| parathyroid gland development | biological process | HOXA3, GCM2, GATA3, PAX1, TGFBR1, CRKL |
| parathyroid hormone secretion | biological process | GATA3 |
| paraxial mesoderm development | biological process | FGFR1, BMPR1A, EPB41L5, NUP133, TEAD2, YAP1, POGLUT1, TCF15, DLL3 |
| paraxial mesoderm formation | biological process | FOXC2, EXOC4, LEF1, WNT11, FOXC1 |
| paraxial mesoderm morphogenesis | biological process | SMAD2, SMAD3 |
| paraxial mesoderm structural organization | biological process | BMPR1A |
| paraxial mesodermal cell fate commitment | biological process | WNT3A, FOXC2 |
| parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | biological process | OPTN, PRKN, MFN2, HDAC6 |
| parturition | biological process | PLA2G4C, CRH, HPGD, MAFF, CRHR1, PTAFR |
| pathogenesis | biological process | MECP2 |
| pathway-restricted SMAD protein phosphorylation | biological process | TGFB1, TGFBR3, ACVR1, TGFB2, TGFBR1, USP15, TGFBR2, BMP2, GDF7, GDF2 |
| pattern recognition receptor signaling pathway | biological process | CLEC7A, LACC1, NOD2, INAVA, NOD1 |
| pattern specification process | biological process | BMP7, SHH, TP63, GLI3, HOXD13, SHROOM3, FOXJ1, HOXA2, NRG3, HOXA5, HES1, DCHS1, BMPR1A, ACVR2B, LHX1, ASCL1, SMO, MFNG, BMP5, APC, C2CD3, SOSTDC1, TBX5, ZEB1, RNF111, PAX1, ASPH, SMAD2, HEY2, SIX1, ALX4, CHRD, MID1, ALX3, EYA1, CDX2, CDX1, RAX, ZIC3, APC2, GLI2, PTCH1, IHH, LFNG, GRHL3, CRKL, NKX2-1 |
| penetration of zona pellucida | biological process | HEXB, TNP2, ACR, HYAL3, B4GALT1 |
| penile erection | biological process | EDNRA, ACVR2A, AVP |
| pentacyclic triterpenoid metabolic process | biological process | IL1B, HTRA2 |
| pentose biosynthetic process | biological process | G6PD, PGD |
| pentose catabolic process | biological process | RPE |
| pentose metabolic process | biological process | FGGY |
| pentose transmembrane transport | biological process | SLC5A1 |
| pentose-phosphate shunt | biological process | G6PD, DERA, TALDO1, RPIA, PGD, TKT, SHPK, RPE, H6PD, RBKS, PGM2, PGLS |
| pentose-phosphate shunt, non-oxidative branch | biological process | TALDO1, RPIA, TKT, SHPK, RPE |
| pentose-phosphate shunt, oxidative branch | biological process | G6PD, PGD, H6PD, PGLS |
| peptide amidation | biological process | PAM, PGLYRP2 |
| peptide antigen assembly with MHC class I protein complex | biological process | TAPBPL, CALR |
| peptide antigen assembly with MHC class II protein complex | biological process | HLA-DRB1, HLA-DRA, HLA-DMB |
| peptide antigen stabilization | biological process | TAPBP |
| peptide antigen transport | biological process | TAP2, CD209 |
| peptide biosynthetic process | biological process | DMD, PCSK1, FURIN |
| peptide catabolic process | biological process | ACE, LTA4H, ERAP1, ERAP2, CPQ, NPEPPS, IDE, NAALADL1, TPP1, NRDC, LNPEP, LVRN, ENPEP, TRHDE, ADAMTS13, ANPEP |
| peptide cross-linking | biological process | FN1, COL3A1, ANXA1, EPB42, TGM1, SPRR1A, TGM5, THBS1, FLG, TGM7, DSP, CSTA, PI3, SPRR1B, TGM4, TGM2, EVPL, TGM6, IVL, ABCA7, KRT2, TGM3 |
| peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan | biological process | DCN, SPOCK2, BGN, EGFLAM, NDNF |
| peptide hormone processing | biological process | CGA, FSHB, LHB, ECE2, ECE1, SCG5, TSHB, BACE2, PCSK2, PCSK6, PCSK4, PCSK1, FURIN, PCSK7, CGB3 |
| peptide hormone secretion | biological process | SMPD3, CPE, EDN1, EDN3, EXOC3L1 |
| peptide metabolic process | biological process | CPN1, PAM, CPM, CPZ, CPXM2, CPXM1, THOP1, CPD, NLN, DNPEP, MIPEP, MME, CPE, AEBP1 |
| peptide modification | biological process | GGT1 |
| peptide secretion | biological process | TRPV1 |
| peptide transport | biological process | SLC15A4, TAP1, SLC15A2, TAP2, TAPBP, ABCB9, SLC15A1 |
| peptidoglycan catabolic process | biological process | SPACA3, PGLYRP4, PGLYRP2 |
| peptidyl-amino acid modification | biological process | ASPHD2, ASPHD1, ASPH |
| peptidyl-arginine ADP-ribosylation | biological process | ART4, ART5, ART1 |
| peptidyl-arginine hydroxylation | biological process | NDUFAF5 |
| peptidyl-arginine methylation | biological process | CARM1, PRMT2, PRMT8, PRMT1, PRMT3, PRMT7, PRMT9 |
| peptidyl-arginine methylation, to asymmetrical-dimethyl arginine | biological process | PRMT6, CARM1, PRMT2, PRMT8, PRMT1 |
| peptidyl-arginine methylation, to symmetrical-dimethyl arginine | biological process | NDUFAF7, PRMT7, PRMT9 |
| peptidyl-arginine N-methylation | biological process | FBXO11, CARM1, PRMT2, PRMT1, PRMT3, PRMT7, PRMT9 |
| peptidyl-arginine omega-N-methylation | biological process | PRMT1, PRMT7 |
| peptidyl-asparagine hydroxylation | biological process | HIF1AN |
| peptidyl-aspartic acid autophosphorylation | biological process | ATP13A2 |
| peptidyl-aspartic acid hydroxylation | biological process | ASPH, HIF1AN |
| peptidyl-cysteine methylation | biological process | RAB6A, RAB3B, RAB3D |
| peptidyl-cysteine oxidation | biological process | PRDX3, TMX3 |
| peptidyl-cysteine S-nitrosylation | biological process | NOS2, S100A9, ADH5, S100A8 |
| peptidyl-cysteine S-trans-nitrosylation | biological process | GAPDH, S100A9 |
| peptidyl-diphthamide biosynthetic process from peptidyl-histidine | biological process | DPH2, DNAJC24, DPH1, DPH6, DPH3, DPH5, DPH7 |
| peptidyl-glutamate ADP-deribosylation | biological process | OARD1, MACROD2, MACROD1 |
| peptidyl-glutamic acid carboxylation | biological process | F10, BGLAP, VKORC1L1, VKORC1 |
| peptidyl-glutamic acid modification | biological process | TTLL4 |
| peptidyl-glutamine methylation | biological process | N6AMT1 |
| peptidyl-histidine dephosphorylation | biological process | PHPT1 |
| peptidyl-histidine hydroxylation | biological process | HIF1AN |
| peptidyl-histidine methylation | biological process | SETD3 |
| peptidyl-histidine methylation, to form tele-methylhistidine | biological process | METTL18 |
| peptidyl-histidine phosphorylation | biological process | NME2 |
| peptidyl-L-cysteine S-palmitoylation | biological process | ZDHHC8, GOLGA7, ZDHHC14, ZDHHC6, ZDHHC23, ZDHHC19, ZDHHC21, ZDHHC11, ZDHHC20, ZDHHC3, ZDHHC2, ZDHHC7, ZDHHC24, ZDHHC4, ZDHHC22, ZDHHC12, ZDHHC18, CLIP3, ZDHHC1 |
| peptidyl-lysine acetylation | biological process | BLOC1S1, EP300, KAT5, ESCO1, KAT2B |
| peptidyl-lysine butyrylation | biological process | EP300 |
| peptidyl-lysine crotonylation | biological process | EP300 |
| peptidyl-lysine deacetylation | biological process | HDAC4, HDAC9, SIRT4, SIRT2, HDAC6, HDAC10 |
| peptidyl-lysine deglutarylation | biological process | SIRT5, SIRT7 |
| peptidyl-lysine demalonylation | biological process | SIRT5 |
| peptidyl-lysine desuccinylation | biological process | SIRT5, SIRT7 |
| peptidyl-lysine dimethylation | biological process | SETD3, EHMT2, EHMT1, SETD7, EEF1AKMT2, SMYD2 |
| peptidyl-lysine glutarylation | biological process | KAT2A |
| peptidyl-lysine hydroxylation | biological process | PLOD1, P3H3, VPS33B, VIPAS39, PLOD2, PLOD3, P3H4 |
| peptidyl-lysine methylation | biological process | METTL21C, EEF1AKMT1, METTL21A, ATPSCKMT, SETD7, EEF1AKMT3, METTL22, VCPKMT, ETFBKMT, CAMKMT, EEF1AKMT2, EEF1AKMT4 |
| peptidyl-lysine modification | biological process | MDM2, ATP7A |
| peptidyl-lysine modification to peptidyl-hypusine | biological process | DOHH |
| peptidyl-lysine monomethylation | biological process | SETD3, SETD4, SETD6, EHMT1, SETD7, EEF1AKMT2, SMYD2, KMT5A |
| peptidyl-lysine N6-acetylation | biological process | NAT8 |
| peptidyl-lysine oxidation | biological process | LOXL2, LOX, LOXL3 |
| peptidyl-lysine propionylation | biological process | EP300 |
| peptidyl-methionine modification | biological process | METAP2, METAP1D, APOA1, PDF, METAP1 |
| peptidyl-proline hydroxylation | biological process | P3H3, P3H1, OGFOD1 |
| peptidyl-proline hydroxylation to 4-hydroxy-L-proline | biological process | P4HB, ERO1A, P4HA3, P4HA1, ERO1B, EGLN1, EGLN2, P4HA2 |
| peptidyl-proline modification | biological process | FKBP6, FKBP10 |
| peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase | biological process | QPCTL, QPCT |
| peptidyl-pyrromethane cofactor linkage | biological process | HMBS |
| peptidyl-serine ADP-deribosylation | biological process | ADPRS |
| peptidyl-serine ADP-ribosylation | biological process | HPF1 |
| peptidyl-serine autophosphorylation | biological process | ATM, DYRK1A, MARK3, PINK1, MAP2K2, ERN1 |
| peptidyl-serine dephosphorylation | biological process | PPP2R2B, PPP2CA, PPP2R2A, NCK1, PPP2R2C, PPP3CA, PPP2R2D, PPTC7, DUSP1, PPP5C, PPP2R1A |
| peptidyl-serine phosphorylation | biological process | BCL2, CDK1, MAPK3, MAPK1, AKT1, GSK3B, ATM, GAS6, MTOR, BRSK2, SRC, MAPK8, ATR, LMTK2, CDC7, PKD1, CAMK4, MAST2, DMPK, MAPK14, CAMK2D, TBK1, CAB39, CSNK1A1, DYRK1A, PDK3, PLK2, DYRK3, MARK3, TDGF1, STK4, MARK2, MAP4K1, DYRK1B, PDGFB, RPS6KB1, PRKCH, CSNK1E, TLK2, UHMK1, TNKS, MORC3, PRKD1, STK38, CAMK1D, MASTL, ROCK2, SYK, HIPK1, MAPKAPK5, PRKX, SRPK2, HIPK4, MKNK2, SGK2, PRKCQ, IKBKE, VRK2, WNK1, STK38L, GRK2, CSNK1D, ROCK1, DYRK2, ULK1, PKN2, TTBK2, PKN3, PINK1, LATS2, TLK1, PRKCB, PLK1, VRK3, SMG1, HIPK3, MAP3K13, TAF1, CSNK2A1, MAP3K12, CDK5R1, HIPK2, MAST4, MAPK9, PRKDC, SGK1, TTK, CLK1, CSNK1G2, MAPK7, SGK3, LATS1, TGFBR1, PRKCZ, PRKCD, CLSPN, CSNK1G1, DCLK1, MAPK12, PRKCE, MAP3K10, MAPKAPK3, STK32B, IKBKB, ILK, TGFBR2, PRKD2, CDK5, PKN1, MKNK1, MAST1, NEK6, MAPK13, PDPK1, MAST3, EPO, PRKCG, AKT2, SBK1, STK32C, DGKQ, CAMK1, PNCK, BRSK1, STK32A, MARK1, CAMK2A, LRRK2, TTBK1, CAMKV, DCLK3, EIF2AK3, SMTNL1, CSNK1A1L |
| peptidyl-serine trans-autophosphorylation | biological process | ERN1 |
| peptidyl-threonine autophosphorylation | biological process | CAMK2A |
| peptidyl-threonine dephosphorylation | biological process | PPM1B, PPP2CA, DUSP8, DUSP5, PPM1G, PDP1, DUSP18, PPM1A, DUSP1, PPP5C, PPM1E, DUSP16, DUSP2, DUSP10 |
| peptidyl-threonine phosphorylation | biological process | BCL2, CDK1, MAPK1, AKT1, GSK3B, MTOR, MAPK8, LMTK2, CAMK2D, WNK3, TBK1, DYRK1A, DYRK3, CIT, ACVR1B, MARK2, DYRK1B, TNKS, ACVR1, PRKD1, ROCK2, HIPK1, HIPK4, WNK1, GRK2, ROCK1, DYRK2, ULK1, HIPK3, TAF1, CSNK2A1, MAP3K12, CDK5R1, HIPK2, PRKDC, NLK, TTK, CLK1, TGFBR1, PRKCD, MAP3K10, MAP2K1, CDC42BPB, OXSR1, TGFBR2, PRKD2, CDK5, PDPK1, SBK1, CDC42BPG, CAD, MYLK2, LRRK2, TTBK1 |
| peptidyl-tyrosine autophosphorylation | biological process | MAPK3, TYK2, KDR, INSR, YES1, IGF1R, SRC, DDR1, DYRK1A, PTK2, ROS1, ITK, SRMS, TEC, TNK1, ABL1, FER, LYN, FGR, AATK, SLA, HCK, LCK, FRK, FES, PTK6, PTK2B, TXK, BLK |
| peptidyl-tyrosine dephosphorylation | biological process | CDC25A, CDC25C, PTEN, ACP1, PTPN11, DUSP6, PTPRJ, PTPDC1, CDKN3, RNGTT, TPTE, MTM1, DUSP13, DUSP11, PTPRR, MDP1, DUSP22, MTMR6, DUSP8, TNS2, DUSP19, DUSP15, PTPRF, MTMR4, PTPRA, PTPN23, PTPN2, PTPN6, PTP4A1, DUSP21, PTPRG, MTMR8, PTPRT, DUSP14, PTPN20, HACD2, PTPN22, PTPRC, DUSP5, PTPN13, SSH2, PTPN9, TIMM50, CDC14B, PTPRM, PTPMT1, PTPRN2, EYA4, MTMR1, DUSP18, PGP, DUSP28, SSH3, PTPRU, PTPN1, PTPRE, UBASH3B, DNAJC6, DUSP1, MTMR3, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, PTPN5, SSH1, EYA1, PTPRS, PTPN14, PTPRZ1, PTPN12, PTPN18, PTPN4, DUSP9, DUSP16, DUPD1, PALD1, CDC25B, DUSP26, EYA2, PTPRD, PTPN3, MTMR14, DUSP2, TPTE2, MTMR7, DUSP10 |
| peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity | biological process | DUSP8, PTPRT, DUSP5, PTPRB, PTPN1, DUSP1, DUSP3, PTPRO, PTPRH, DUSP16, ACP4, DUSP2, DUSP10 |
| peptidyl-tyrosine phosphorylation | biological process | EGFR, EGF, ERBB2, HSP90AA1, FLT1, FGFR2, FGFR3, WEE1, AXL, KDR, FGFR1, IL5, INSR, KIT, SRC, NRG1, FGF17, CLK3, FGF8, TWF1, NTRK1, FGF3, FGF9, DDR1, RYK, ROR1, JAK2, DYRK1A, DYRK3, NEK1, PEAK1, ALK, DYRK1B, PDGFB, LTK, BAZ1B, EPHB2, TIE1, PTK2, FLT4, SYK, CLK2, HIPK1, ABI2, PTPN6, HIPK4, ZAP70, TEK, NTRK2, MAP2K4, MAP2K3, EPHB1, TTN, DYRK2, SRMS, MAP2K7, TEC, MELK, EPHA6, HIPK3, JAK1, MAP2K2, HIPK2, CLK4, RIPK2, ABL1, FER, TTK, CLK1, ABI1, LYN, PRKCD, DSTYK, ABL2, EPHA4, SCYL1, EPHA1, MAP2K6, BTK, FGR, EIF2AK2, ERBB3, MAP2K1, RET, PDGFRB, EPHA2, MAP2K5, EPHA7, HCK, MST1R, IL12RB2, LCK, PDGFRA, EPHA3, EPHA8, FGFR4, CSK, CAMKK2, TESK2, FES, CSF1R, INSRR, MATK, JAK3, EPHB3, EPHB4, ROR2, EPHA10, MERTK, PKDCC, PTK2B, RELN, TTBK1, ABI3, EPHB6, BLK, TYRO3, EFEMP1 |
| peptidyl-tyrosine sulfation | biological process | TPST1 |
| pericardium development | biological process | TBX5, SMAD2, BMP2, CCM2, SMAD3, RPGRIP1L |
| pericardium morphogenesis | biological process | SOS1, NOTCH1, LRP6, BMP5, TBX20 |
| pericentric heterochromatin assembly | biological process | ZNFX1, HELLS, H3-3A, CENPV |
| pericyte cell differentiation | biological process | EPHA2 |
| peripheral nervous system axon regeneration | biological process | APOD, APOA1, TNC, MAP1B, NEFL |
| peripheral nervous system development | biological process | SOX10, ERBB2, NRG1, GDNF, ASIC2, PMP22, ALDH3A2, NTF4, EDNRB, EGR3, EGR2, NFASC, ADGRB2, ERBB3, SERPINI1, ADGRB1, GFRA3, NTF3, NF1, SCN8A, UGT8 |
| peripheral nervous system myelin formation | biological process | DICER1, NCMAP |
| peripheral nervous system myelin maintenance | biological process | SOD1, AKT1, PRX, FA2H, SH3TC2, NDRG1, AKT2 |
| peripheral nervous system neuron axonogenesis | biological process | ISL1, NEFH, SLC25A46 |
| peripheral nervous system neuron development | biological process | ISL1, RUNX1, NTRK2, ONECUT2, HOXD10, ETV1, POU4F1, HAND2 |
| peripheral nervous system neuron differentiation | biological process | POU4F1 |
| peripheral T cell tolerance induction | biological process | AIRE |
| peristalsis | biological process | GDNF, NEUROG1, DLG1, TIFAB, DRD1, DRD2, P2RX3, P2RX2 |
| PERK-mediated unfolded protein response | biological process | CXCL8, ATF3, NFE2L2, HSPA5, DDIT3, IGFBP1, ASNS, HERPUD1, ATF4, EIF2S1, EIF2AK3, CCL2 |
| peroxisomal membrane transport | biological process | ABCD1 |
| peroxisome fission | biological process | DNM1L, PEX19, MFF, PEX11B, FIS1, PEX11G, PEX11A, ACOX1, SEC16B |
| peroxisome membrane biogenesis | biological process | PEX19, PEX3, PEX11A, PEX16 |
| peroxisome organization | biological process | PEX10, PEX7, PEX2, PEX19, SCP2, PEX11B, PLAAT3, TMEM135, LONP2, PEX12, PEX3, PEX14, PEX1, PEX11A, PEX16, ABCD1, SEC16B |
| peroxisome proliferator activated receptor signaling pathway | biological process | PPARG, PDK3, FAM120B, ALOXE3, ACTN4 |
| peroxisome transport along microtubule | biological process | PEX14 |
| Peyer's patch development | biological process | STAT5B, NKX2-3, ADA, ID2, RORC |
| Peyer's patch morphogenesis | biological process | RET |
| pH elevation | biological process | SLC4A1 |
| pH reduction | biological process | ATP6V1B1, ATP6AP1, TCIRG1, ATP4B |
| phagocytosis | biological process | AXL, GAS6, PIK3CA, CDC7, ELANE, RAB11FIP2, MEGF10, LYST, KIAA1109, MYD88, EIF2AK1, CD93, CORO1C, ANXA3, TULP1, ANXA1, PLD4, TAFA4, LDLR, RAB5A, PIP5K1A, ANXA11, CEBPE, TM9SF4, MESD, GULP1, ELMO2, CDC42SE2, ABL1, TICAM2, DOCK1, RUBCN, GATA2, TUSC2, SLC11A1, ITGB2, IRF8, LRP1, ELMO3, C1orf43, ADGRB1, PLA2G5, NCF4, UNC13D, ICAM5, HCK, ICAM3, CDC42SE1, PECAM1, CORO1A, SLAMF1, VAV1, PRTN3, ABCA7, PIP5K1C, ITGAL, MYO7A, P2RY6, SH3BP1, MYO1G, SYT7, ADORA2A, MERTK, TUB, ELMO1, TYRO3 |
| phagocytosis, engulfment | biological process | AIF1, FCGR2B, MFGE8, ITGAM, MARCO, IGLL5, GULP1, VAMP7, DOCK1, BIN2, TREM2, ITGB2, ADGRB1, IGLL1, FCER1G, ARHGAP25, MYH9, ARHGAP12, SH3BP1, ELMO1, CD36 |
| phagocytosis, recognition | biological process | CLEC7A, TULP1, COLEC12, SCARB1, MFGE8, IGLL5, ADGRB1, IGLL1, TUB, CD36 |
| phagolysosome assembly | biological process | SRPX, P2RX7, CORO1A, MYO7A |
| phagolysosome assembly involved in apoptotic cell clearance | biological process | RAB14 |
| phagosome acidification | biological process | ATP6V0A2, ATP6V1B1, ATP6V1D, ATP6V1G1, ATP6V1B2, RAB38, SLAMF8, ATP6V1E1, RAB20, ATP6V0E1, ATP6V1G2, ATP6V1A, ATP6V1G3, RAB7A, RAB39A, ATP6V0E2, ATP6V1C1, ATP6V1H, ATP6V0D1, ATP6V0B, ATP6V0A4, ATP6V1F, TCIRG1, ATP6V1E2, ATP6V0C, ATP6V1C2, ATP6V0A1 |
| phagosome maturation | biological process | RAB31, RAB32, RAB14, RAB7A, UNC13B, RAB34 |
| phagosome-lysosome docking | biological process | CLN3 |
| phagosome-lysosome fusion | biological process | RAB20, RAB7A, RAB39A, CLN3, PLA2G5, RAB34, SYT7, TMEM175 |
| phagosome-lysosome fusion involved in apoptotic cell clearance | biological process | SPG11 |
| pharyngeal arch artery morphogenesis | biological process | HES1, BMPR1A, TGFB2, ADGRF5, FOLR1 |
| pharyngeal system development | biological process | FGF8, ISL1, ECE1, NKX3-1, ACVR1, GATA3, BMP5, TGFBR1, RIPPLY3, SIX1, SIX4, EYA1, NKX2-5, PLXNA2, PTCH1 |
| pharynx development | biological process | FOXE1, CRKL, TBX2 |
| phenol-containing compound metabolic process | biological process | CYP17A1, STAR, SULT1B1, SULT1A2 |
| phenylacetate catabolic process | biological process | ACAA1 |
| phenylalanine transport | biological process | SLC3A2 |
| phenylalanyl-tRNA aminoacylation | biological process | FARS2, FARSB, FARSA |
| phosphate ion homeostasis | biological process | FGF23, SFRP4, FGFR4, SLC34A1 |
| phosphate ion transmembrane transport | biological process | SLC20A1, SLC17A1, ANKH, SLC37A3, SLC25A3, SLC37A4, SLC25A10, SLC37A1, XPR1, SLC20A2, ADAMTS8, SLC34A1, SLC37A2 |
| phosphate ion transport | biological process | SLC17A3, SLC20A1, SLC17A1, ANKH, SLC34A3, XPR1, IP6K2, SLC20A2, SLC34A1, SLC17A7 |
| phosphate-containing compound metabolic process | biological process | TGFB1, G6PC3, IMPA1, SLC20A1, PPA2, ENPP3, FGF23, LHPP, ENPP1, PTPRB, ACYP1, PPA1, IMPA2, INPP1, ACYP2, PTPRD, INPP5D, SLC17A2 |
| phosphatidic acid biosynthetic process | biological process | PLA2G2A, LCLAT1, AGPAT1, PLA2G10, ALPI, DGKE, ABHD5, PLD1, AGPAT2, ACP6, DGKB, GNPAT, DGKA, SLC27A1, DDHD2, DGKG, DGKZ, DDHD1, LIPH, AGPAT3, PNPLA3, GPD1L, PLA2G4A, GPAM, PLA2G1B, DGKH, AGPAT4, PLA2G12A, PLD2, PLA2G5, GPAT3, LPCAT1, LPCAT4, DGKQ, DGKD, ABHD4, PLA2G2D |
| phosphatidic acid metabolic process | biological process | PLA2G2A, PLA2G10, PLA2G3, DGKH |
| phosphatidylcholine acyl-chain remodeling | biological process | PLA2G6, PLA2G2A, PNPLA8, MBOAT2, PLA2G10, DBI, PLAAT3, PLA2G4C, PLA2G3, TMEM86B, PLA2G4A, PLA2G1B, PLA2G12A, PLA2G5, LPCAT2, LPCAT1, LPCAT3, LPCAT4, PLA2G2D, PLB1 |
| phosphatidylcholine biosynthetic process | biological process | CHKA, CEPT1, SLC44A4, SLC44A3, SLC44A5, CHPT1, SLC44A1, FABP5, PEMT, LPIN1, SLC27A1, STARD7, PCTP, PCYT1B, PHOSPHO1, STARD10, APOA1, CSNK2A1, MFSD2A, LPIN2, LPCAT1, CHAT, LPCAT3, SLC44A2, LPIN3, PCYT1A, LCAT |
| phosphatidylcholine catabolic process | biological process | PNPLA8, PLA2G10, ENPP2, GDPD3, LIPC, PLA2G4A, PLA2G15, PLA2G7, PLA2G5, PNPLA7 |
| phosphatidylcholine metabolic process | biological process | PON1, PLA2G10, PLAAT1, PLA2G3, GPLD1, APOA1, MECP2, PNPLA6, PLA2G15, PLA2G1B, APOA5, CETP, PLA2G2D, LCAT |
| phosphatidylethanolamine acyl-chain remodeling | biological process | PLA2G6, PLA2G2A, PNPLA8, MBOAT2, PLA2G10, PLAAT3, PLA2G4C, PLA2G3, PLA2G4A, PLA2G1B, PLA2G12A, PLA2G5, LPCAT3, LPCAT4, ABHD4, PLA2G2D |
| phosphatidylethanolamine biosynthetic process | biological process | CHKA, CEPT1, ETNK2, LPIN1, SLC27A1, PHOSPHO1, PCYT2, ETNK1, LPIN2, PISD, LPIN3, SELENOI |
| phosphatidylethanolamine catabolic process | biological process | PNPLA8, PLA2G15 |
| phosphatidylethanolamine metabolic process | biological process | PLA2G10, PLA2G3, PLA2G2D |
| phosphatidylglycerol acyl-chain remodeling | biological process | PLA2G2A, PLA2G10, SERAC1, PLA2G3, PLA2G4A, PLA2G1B, PLA2G12A, PLA2G5, LPCAT1, CRLS1, LPCAT4, PLA2G2D |
| phosphatidylglycerol biosynthetic process | biological process | SLC27A1, PTPMT1, PGS1 |
| phosphatidylglycerol catabolic process | biological process | PLA2G4A |
| phosphatidylglycerol metabolic process | biological process | PLA2G10, PLA2G3, PLA2G1B |
| phosphatidylinositol 3-kinase signaling | biological process | ERBB2, IGF1, IGF1R, C1QBP, PIK3C2A, PIK3R1, XBP1, LTK, PREX2, PLEKHA1, GATA3, SIRT2, IRS1, KBTBD2, ZFP36L1, PIK3CG, PIK3C2B, ERBB3, MYO16, PIK3CD, EDN1, CD160, NYAP1, PIK3R2, PEAR1, PIK3R5, NF1, HTR2B, TYRO3 |
| phosphatidylinositol 5-phosphate metabolic process | biological process | PIKFYVE, MTMR3 |
| phosphatidylinositol acyl-chain remodeling | biological process | PLA2G2A, LCLAT1, PLA2G10, PLAAT3, PLA2G4C, PLA2G4A, PLA2G1B, PLA2G12A, PLA2G5, PLA2G2D, MBOAT7 |
| phosphatidylinositol biosynthetic process | biological process | PTEN, PIK3CA, INPP4B, SYNJ1, IMPA1, MTM1, PIK3C2A, MTMR6, PIK3R1, PIKFYVE, MTMR4, INPP5F, RAB4A, OCRL, RUFY1, PLEKHA1, PI4K2B, PITPNM3, PLEKHA3, SYNJ2, RAB5A, ARF1, PIK3C3, SLC27A1, MTMR8, PIP5K1A, PLEKHA4, RAB14, ARF3, INPP4A, PIP4K2A, PTPN13, MTMR9, SACM1L, PIP5K1B, CDS1, INPP5K, MTMR12, MTMR1, PIK3R3, PLEKHA2, PIP4K2C, SH3YL1, PIK3R4, PI4K2A, PITPNM1, VAC14, PIK3CG, MTMR3, PIK3C2B, PIP4K2B, PLEKHA8, PITPNM2, PIK3CD, CDIPT, FGF2, PI4KB, PIK3R2, PIP5K1C, PI4KA, PIK3R6, PIK3R5, INPP5E, PLCG2, MTMR14, INPP5D, MBOAT7, TPTE2, MTMR7 |
| phosphatidylinositol catabolic process | biological process | INPP5F |
| phosphatidylinositol dephosphorylation | biological process | PTEN, SYNJ1, MTM1, MTMR6, MTMR4, INPP5F, OCRL, INPP5A, SYNJ2, MTMR8, MTMR11, MTMR9, SACM1L, INPP5K, MTMR12, MTMR1, INPP5B, MTMR3, PIP4P1, INPP5E, INPP5D, MTMR7, PIP4P2 |
| phosphatidylinositol metabolic process | biological process | SYNJ1, PLCH2, PIKFYVE, PLEK, IP6K3, PLA2G3, PIP5K1A, PIP4K2A, PIP5K1B, PIP4K2C, PIP4K2B, PDGFRB, IP6K2, PIP5K1C, CSF1R, INPP5E, PLCD4, IPMK, MBOAT7 |
| phosphatidylinositol phosphorylation | biological process | EGFR, EGF, KITLG, ERBB2, FGFR2, FGFR3, FGFR1, KIT, PIK3CA, NRG1, FGF17, FGF8, PTPN11, FGF3, FGF9, IMPA1, EFR3A, CISH, PIK3C2A, SOCS2, PIK3R1, PIKFYVE, SOCS5, SOCS4, FAM126A, BPNT2, PI4K2B, SOCS1, PIK3C3, IP6K3, PIP5K1A, SLA2, PIP4K2A, SMG1, TTC7A, PIP5K1B, PIK3R3, PIP4K2C, PI4K2A, EFR3B, SOCS7, IMPA2, PIK3CG, PIK3C2B, SOCS6, PIP4K2B, TMEM150A, PIK3CD, INPP1, PI4KB, IP6K2, PIK3R2, PIP5K1C, PI4KA, PIK3R6, TTC7B, FAM126B, IPMK, SOCS3 |
| phosphatidylinositol-3-phosphate biosynthetic process | biological process | FGFR2, FGFR3, ATM, FGFR1, PIK3CA, FGF17, FGF8, PTPN11, FGF3, FGF9, INPP4B, PIK3C2A, PIKFYVE, PIK3C3, INPP4A, PIK3R3, PIK3CG, PIK3C2B, PIK3CD |
| phosphatidylinositol-mediated signaling | biological process | EGFR, EGF, KITLG, ERBB2, FGFR2, FGFR3, AKT1, FGFR1, MTOR, PTEN, IGF1, IGF1R, KIT, PIK3CA, NRG1, FGF17, NGF, EZR, FGF8, PTPN11, NTRK1, FGF3, FGF9, PLCH2, PIK3C2A, OGT, PIK3R1, RPS6KB1, INPP5F, PLCL1, PIK3C3, PLCB2, PLCB3, IRS2, IRS1, PLCD1, NPR3, PLCE1, GAB2, CA8, NCS1, EXOC1, PIK3CG, PIK3C2B, PDGFRB, PITPNM2, PIK3CD, PDGFRA, PTAFR, PI4KB, PIK3R2, CSF1R, PI4KA, GPR143, PLCD4, PLCG2, PLCH1, PLCL2, ZP3 |
| phosphatidylserine acyl-chain remodeling | biological process | PLA2G2A, PLA2G10, PLAAT3, OSBPL5, OSBPL8, PLA2G4A, PLA2G1B, OSBPL10, PLA2G12A, PLA2G5, LPCAT3, LPCAT4, PLA2G2D, PLA1A |
| phosphatidylserine biosynthetic process | biological process | SLC27A1, PLSCR1, PTDSS2, PTDSS1 |
| phosphatidylserine catabolic process | biological process | ABHD12B, ABHD12, ABHD16A, ABHD16B |
| phosphatidylserine exposure on apoptotic cell surface | biological process | XKR4, XKR6, XKR8 |
| phosphatidylserine exposure on blood platelet | biological process | ANO6 |
| phosphatidylserine metabolic process | biological process | PLA2G10, PLA2G3, SERINC3, SERINC1, SERINC5, PLA1A, SERINC2 |
| phosphoanandamide dephosphorylation | biological process | PTPN22 |
| phosphocreatine biosynthetic process | biological process | CKM, CKMT2, CKB |
| phospholipase C-activating adrenergic receptor signaling pathway | biological process | ADRA2A |
| phospholipase C-activating angiotensin-activated signaling pathway | biological process | AGTR1, ACTN2 |
| phospholipase C-activating dopamine receptor signaling pathway | biological process | SLC9A3R1, GNA11, GNAQ, GNA14, DRD3, DRD1, GNA15, DRD2 |
| phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway | biological process | GNA15, CHRM1, CHRM2 |
| phospholipase C-activating G protein-coupled glutamate receptor signaling pathway | biological process | HOMER1, GRM5 |
| phospholipase C-activating G-protein coupled receptor signaling pathway | biological process | ESR1, LHCGR, FPR1, KISS1R, F2R, P2RY4, F2RL3, P2RY11, PTH1R, HRH1, GNB1, CCKAR, NMBR, AGTR1, P2RY12, NPR3, CXCR2, FPR3, ADRA1A, GPR4, PLCE1, EDNRB, LTB4R, PTGER3, OPRD1, CX3CR1, TGM2, C3AR1, NMUR2, NMUR1, HTR2C, P2RY1, C5AR2, FPR2, ADRA1D, GNA15, HCRT, NTSR2, ADRA1B, GNG13, CMKLR1, P2RY2, P2RY6, ANO1, AGT, OPRK1, C5AR1, HTR2B, MC3R, GPR139 |
| phospholipase C-activating serotonin receptor signaling pathway | biological process | HTR2C |
| phospholipase C-inhibiting G protein-coupled receptor signaling pathway | biological process | PLEK |
| phospholipase D-activating G protein-coupled receptor signaling pathway | biological process | EDN1 |
| phospholipid biosynthetic process | biological process | HEXB, CHKA, CEPT1, LCLAT1, MBOAT2, AGPAT1, FITM1, PLAAT3, ABHD5, CHPT1, PPARD, AGPAT2, ETNK2, GNPAT, TMEM38B, PEMT, SERAC1, PIP5K1A, PCYT1B, TAMM41, SERINC1, PCYT2, ISYNA1, AGPAT3, PNPLA3, PTPMT1, CDS1, ETNK1, PTDSS2, GPAM, PGS1, SERINC5, AGPAT4, GPAT3, CDIPT, FADS1, LPCAT2, LPCAT1, CRLS1, PTDSS1, LPCAT3, LPCAT4, PISD, PCYT1A, MBOAT7, SELENOI |
| phospholipid catabolic process | biological process | ENPP2, PLA2G4C, PLD1, ABHD12, LIPG, NAPEPLD, ANGPTL3, PLA2G4A, PLA2G7, PLD2, PLA2G5, ABHD6, PNLIPRP2, PLCG2 |
| phospholipid dephosphorylation | biological process | EPHX2, PLPP2, PLPPR2, PLPP1, SGPP2, PLPP5, PLPPR4, PLPP3, PLPPR1, PLPPR3, PLPP4, PLPP6, SGPP1 |
| phospholipid efflux | biological process | APOE, ABCA12, ABCG1, APOA1, APOC1, APOA5, ABCA7, APOC3 |
| phospholipid homeostasis | biological process | LIPG, FABP3, ABCG1, ANGPTL3, APOA1, GPAM, HNF4A, TLCD1, CETP, ABCB11 |
| phospholipid metabolic process | biological process | GPX4, PLA2G2A, MBOAT2, AGPAT1, PLA2G10, LPL, PLAAT3, ENPP2, PLA2G4C, PLPP2, GDPD3, AGPAT2, PLPPR2, ACP6, PLPP1, PLA2G3, PLCB2, CLN8, PLCD1, NAPEPLD, LGALS13, ANGPTL3, PIP4K2A, PROCA1, PLPP5, APOA1, PLA2G4A, PLA2G15, GDE1, PLA2G1B, AGPAT4, PLA2G12A, PIP4K2B, PLPPR4, PLAA, PLA2G5, PLPP3, PLPPR1, LPCAT2, PIP4P1, LPCAT1, ALOX15B, LPCAT3, LPCAT4, PCSK9, PLPPR3, CYP2W1, PLA2G2D, TNFAIP8L3, PLPP4, PLB1, MBOAT7, LCAT, GDPD1, PLA2G12B, NKX2-1 |
| phospholipid transfer to membrane | biological process | ABCA4, P2RX7 |
| phospholipid translocation | biological process | ATP10B, ATP8B3, TMEM30B, ATP8B4, ATP8B2, ATP10D, ANO6, KCNN4, ABCA4, ATP9B, ATP9A, TMEM30A, ATP8A2, ATP11B, ABCB4, ATP11A, ATP8A1, P2RX7, ATP10A, SLC66A2, ABCA7, ATP8B1 |
| phospholipid transport | biological process | NPC2, PITPNB, ATP10B, SCP2, ATP8B3, ATP8B4, PRELID1, ATP8B2, ATP10D, PITPNA, PRELID2, LDLR, SCARB1, OSBPL5, OSBPL8, OSBPL2, PCTP, PRELID3A, ATP9B, PITPNC1, TRIAP1, ATP9A, APOA1, TMEM30A, ATP8A2, ATP11B, PITPNM1, ATP11A, OSBPL10, ATP8A1, ATP10A, PITPNM2, C2CD2L, PRELID3B, CETP, ATP8B1, TNFAIP8L3, MTTP |
| phosphorelay signal transduction system | biological process | MMS19 |
| phosphorylation | biological process | EGFR, AMHR2, TSSK4, TSSK6, AURKC, ERBB2, CDK1, FLT1, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, KDR, GSK3B, ATM, PANK2, FGFR1, PRPS2, CSNK2A2, STAT3, MTOR, BRSK2, INSR, PGK2, YES1, IGF1R, KIT, SRC, CHKA, PIK3CA, MAPK8, ATR, BMPR2, LMTK2, CDC7, PDXK, RAF1, MAK, CLK3, CDK9, PGK1, NTRK1, DDR1, CAMK4, MAST2, PPIP5K1, CKM, TOP1, LIMK2, DMPK, MAPK14, PRPS1L1, RYK, ROR1, CAMK2B, CAMK2D, GK2, PDK4, DGKK, ADPGK, WNK3, NMRK1, TBK1, MOK, NME7, JAK2, PFKM, GK, GRK5, CSNK1A1, STK3, DYRK1A, PDK3, NADK2, NEK8, SPHK2, STK36, PLK2, MAP3K4, EEF2K, PIK3C2A, DYRK3, KALRN, MARK3, SEPHS1, CDK7, DGKE, AK2, ADK, MAP4K2, MAPK6, N4BP2, SGMS2, COQ8A, NEK1, RPS6KB2, CIT, FAM20B, CDK14, CKMT2, ACVR1B, PFKP, STK4, MAPK11, MARK2, ADCK2, MAP4K1, FGGY, WNK4, STK31, ALK, PIKFYVE, DYRK1B, MAP3K7, NADK, RPS6KB1, PRKCH, LTK, MAPK4, CSNK1E, IRAK1, TLK2, UHMK1, COQ8B, ALPK1, PASK, SEPHS2, EIF2AK1, MAP3K20, STK17A, BAZ1B, AK6, RPS6KL1, STK25, BUB1, BUB1B, STK17B, PRKACB, EPHB2, TIE1, ACVR1, PTK2, PMVK, PRKD1, STK38, TKFC, CAMK1D, MASTL, CDK |
| phosphorylation of RNA polymerase II C-terminal domain | biological process | GTF2H3, CDK7, CCNH, CDK13, GTF2H1, GTF2H4, CDK12, GTF2H5 |
| photoperiodism | biological process | CLOCK, NMU, AANAT |
| photoreceptor cell development | biological process | ARL3, RP1, DCX, RP1L1 |
| photoreceptor cell maintenance | biological process | MAK, NPHP4, USH1G, BBS2, ERCC6, TULP1, ABCA4, BBS12, MKKS, USH2A, RP1, CDHR1, BBS4, USH1C, USP45, CIB2, DRAM2, ADGRV1, CRB1, MDM1, NPHP3, NXNL2, ATP1B2, RDH12, CNGB1, LCA5, RHO, CROCC, RP1L1, BBS1, CDH23, ESRRB, TUB, IQCB1, PCDH15, NXNL1, SPATA7 |
| photoreceptor cell morphogenesis | biological process | CDHR1, MFSD2A, C8orf37, CABP4 |
| photoreceptor cell outer segment organization | biological process | NPHP4, AHI1, PCARE, RP1, CDHR1, BBS4, MFSD2A, CRB1, CNGB1, TOPORS |
| phototransduction | biological process | RCVRN, ASIC2, TRPC3, OPN5, GNAT2, UNC119, NR2E3, GPR88, GNGT1, CDS1, PITPNM1, PLEKHB1, CABP4, CNGB1, GNGT2, RHO, OPN4, OPN3 |
| phototransduction, UV | biological process | OPN5 |
| phototransduction, visible light | biological process | ABCA4, RP1, GNA11, GNAQ, AIPL1, PDE6B, RHO |
| phthalate metabolic process | biological process | SRD5A2, CYP17A1, STAR, TH |
| phylloquinone catabolic process | biological process | CYP4F3, CBR3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| phytanic acid metabolic process | biological process | HACL1 |
| phytoalexin metabolic process | biological process | DDC, TH |
| phytol metabolic process | biological process | ALDH3A2, PECR |
| phytosphingosine biosynthetic process | biological process | ACER3 |
| piecemeal microautophagy of the nucleus | biological process | RB1CC1, ATG13 |
| pigment cell differentiation | biological process | CD63 |
| pigment granule aggregation in cell center | biological process | MKKS |
| pigment granule localization | biological process | RAB27A, MYO7A |
| pigment granule maturation | biological process | CD63 |
| pigment granule organization | biological process | BCL2 |
| pigment granule transport | biological process | RAB27A, MYO7A |
| pigmentation | biological process | BCL2, KIT, ARCN1, LYST, RAB27A, AP3B1, ASIP, RACK1, HPS3, CITED1, MYO5A, MITF, CD63, TYR, EDNRB, MYSM1, ATP7A, SZT2, OCA2, EN1, TH, EDA, EDAR, VANGL1, DRD2, NF1, TYRP1, MC1R, DCT, HPS5 |
| pilomotor reflex | biological process | HPN, ADRA1A |
| pinocytosis | biological process | PPT1, SNX5, EHD4, AHSG |
| piRNA metabolic process | biological process | PIWIL2, PIWIL1, DDX4, PIWIL4, TDRD9, MAEL, MOV10L1, FKBP6, TDRKH, HENMT1, EXD1, TDRD12, TDRD1 |
| pituitary gland development | biological process | SOX3, NR0B1, SRD5A1, BMP4, CDH1, SOX2, ALDH1A2, ISL1, LHX3, HES1, BMPR1A, MSX1, ETS1, SIX3, RBPJ, GATA2, GLI1, HESX1, SALL1, GLI2, TBX19, FGF10, NKX2-1 |
| placenta blood vessel development | biological process | NR2F2, PKD1, RBM15, SPINT1, PKD2, VASH2, ARID1A, ITGB8, MAP2K1, VASH1, SOCS3 |
| placenta development | biological process | SOD1, DCN, NODAL, HSD17B2, LEP, PPARG, MAPK14, ETV2, NDP, MAP3K4, LHX3, PPARD, PHLDA2, RTCB, MC2R, PTK2, ETNK2, ASCL2, CITED1, GJB3, BIRC2, TTPA, CDKN1B, BIRC6, ADA, E2F7, E2F8, CCNF, CUL7, MME, CDX2, ALKBH1, TEX19, ADAM19, ANG, HTRA1, LHX4, CCDC134, CDX4 |
| planar cell polarity pathway involved in axis elongation | biological process | VANGL2, WNT11, MAGI2 |
| planar cell polarity pathway involved in axon guidance | biological process | RYK, FZD3, VANGL2, CELSR3 |
| planar cell polarity pathway involved in gastrula mediolateral intercalation | biological process | WNT11 |
| planar cell polarity pathway involved in heart morphogenesis | biological process | VANGL2 |
| planar cell polarity pathway involved in neural tube closure | biological process | PTK7, DVL1, FZD2, CELSR1, VANGL2, DVL2, SFRP2, DVL3, FZD1, GRHL3 |
| planar dichotomous subdivision of terminal units involved in lung branching morphogenesis | biological process | CELSR1, VANGL2 |
| plasma cell differentiation | biological process | NKX2-3, ITM2A |
| plasma kallikrein-kinin cascade | biological process | PRCP, F12 |
| plasma lipoprotein particle assembly | biological process | MTTP |
| plasma lipoprotein particle clearance | biological process | LDLR, CD36 |
| plasma lipoprotein particle oxidation | biological process | PLA2G7 |
| plasma lipoprotein particle remodeling | biological process | APOC1 |
| plasma membrane ATP synthesis coupled electron transport | biological process | COA6 |
| plasma membrane bounded cell projection organization | biological process | ATP1B2 |
| plasma membrane fusion | biological process | NSF, TIE1, MYMK |
| plasma membrane lactate transport | biological process | SLC16A7, SLC16A1, EMB |
| plasma membrane organization | biological process | MTSS2, BAIAP2L1, BAIAP2, SERP1, ANK3, SLC9A3R1, SPTBN1, OSBPL2, MTSS1, CAV3, OTOF, FER1L5, A4GALT, CRB1, P2RX7, TLCD1, MYOF, DYSF, BAIAP2L2 |
| plasma membrane phospholipid scrambling | biological process | ANO6, PLSCR4, PLSCR1, P2RX7, SLC4A1, PLSCR2 |
| plasma membrane raft assembly | biological process | FLOT1 |
| plasma membrane raft distribution | biological process | PTPRC |
| plasma membrane raft organization | biological process | FA2H, CLN3, ABCA7 |
| plasma membrane repair | biological process | MYH10, SYTL4, CAV3, MYOF, MYH9, DYSF, AHNAK2, TRIM72, SYT7 |
| plasma membrane selenite transport | biological process | SLC39A8 |
| plasma membrane to endosome transport | biological process | RAB11A, USP6NL, RAB35, COMMD1, SORT1, RAB5B, RAB5C, SGSM3 |
| plasma membrane tubulation | biological process | CHMP4A, FNBP1L, SNX33, PACSIN2, SNX9, BIN2, EHD2, PACSIN3, MICALL1, BIN3, PACSIN1, CAVIN2 |
| plasmacytoid dendritic cell antigen processing and presentation | biological process | CLEC4A |
| plasminogen activation | biological process | PLAT, DHCR24, FGG, FGB, FGA, APOH |
| platelet activating factor biosynthetic process | biological process | CHPT1, PLA2G4C, PLA2G4A, PLA2G5, LPCAT2 |
| platelet activating factor catabolic process | biological process | PLA2G10, PLA2G7 |
| platelet activating factor metabolic process | biological process | PLA2G7 |
| platelet activation | biological process | IL6, VWF, MAPK3, MAPK1, AXL, AKT1, GAS6, F5, SRC, PIK3CA, RAF1, CD9, F2R, PTPN11, SAA1, CX3CL1, DGKK, F2RL3, GP1BB, DGKE, RAP2B, PIK3R1, TRPC3, MPIG6B, PRKCH, TREML1, VAV3, GP6, DGKB, COL3A1, SYK, GNB1, FGG, PTPN6, WNT3A, DGKI, GP9, DGKA, YWHAZ, PRKCQ, PF4, ITPR3, P2RY12, FGB, ADRA2A, DGKG, DGKZ, CLEC1B, PRKCB, ITGB3, COL1A2, GNA12, C1GALT1C1, TRPC7, ACTN1, GNA11, GNG2, PLSCR1, GNAQ, VAV2, LYN, PRKCD, ITPR1, DGKH, UBASH3B, GNA14, F8, PIK3CG, PRKCE, LCP2, ADRA2B, P2RY1, ITPR2, PDPN, F2RL2, SRF, FCER1G, GNA15, FGA, FZD6, HRG, LCK, GP1BA, PF4V1, VAV1, ADRA2C, ADAMTS13, PDPK1, F2, PRKCG, ARRB2, PIK3R6, PIK3R5, CD40, DGKQ, MERTK, DGKD, PLCG2, ENTPD2, TYRO3 |
| platelet aggregation | biological process | GNAS, GAS6, HSPB1, ACTB, RAP2B, ITGA2B, MYL12A, PLEK, FGG, PTPN6, WNT3A, P2RY12, FGB, HBB, ITGB3, ACTN1, BLOC1S4, ACTG1, FIBP, VCL, CSRP1, MPL, STXBP3, UBASH3B, CLIC1, PIK3CG, ILK, FGA, PDGFRA, MYH9, FERMT3, GP1BA, COMP, TSPAN32, TLN1, PEAR1, METAP1, GATA1, TYRO3 |
| platelet alpha granule organization | biological process | ZNF385A, VPS33B |
| platelet degranulation | biological process | SOD1, TIMP1, EGF, TGFB1, TGFB3, VEGFA, IGF2, VWF, SERPINE1, GAS6, SERPINA1, ALB, TF, APP, CLU, F5, TMSB4X, A2M, IGF1, HGF, FN1, CD9, LGALS3BP, TUBA4A, ECM1, SERPINA3, LHFPL2, SCCPDH, CTSW, CFD, PDGFB, ITGA2B, VTI1B, WDR1, ORM1, PLEK, TIMP3, MANF, SYTL4, FGG, OLA1, MAGED2, QSOX1, PROS1, PSAP, APLP2, RAB27B, THBS1, SERPINF2, LAMP2, SELENOP, PF4, CD63, ACTN2, TTN, FGB, ALDOA, SELP, SERPINA4, CDC37L1, SCG3, PDGFA, CALM1, NHLRC2, FAM3C, APOA1, ITGB3, SRGN, TGFB2, ACTN1, LYN, VCL, VEGFC, ORM2, HABP4, F8, CLEC3B, TAGLN2, MMRN1, CHID1, PLG, FGA, PPBP, VEGFB, CD109, TOR4A, HRG, SERPING1, PECAM1, FERMT3, RARRES2, ITIH4, TLN1, ISLR, LEFTY2, ABCC4, ACTN4, STXBP2, PHACTR2, AHSG, ITIH3, SPP2, GTPBP2, BRPF3, APOH, CD36, TMX3 |
| platelet dense granule organization | biological process | F2R, BLOC1S2, F2RL3, RAB38, AP3B1, BLOC1S1, DTNBP1 |
| platelet formation | biological process | CASP3, CASP9, CIB1, PTPN11, ZNF385A, MPIG6B, WDR1, PTPN6, MEF2C, CLEC1B, EP300, ACTN1, SRF, MYH9, VPS33A, NBEAL2, ZFPM1, GATA1 |
| platelet maturation | biological process | FGG |
| platelet morphogenesis | biological process | C1GALT1C1, ACTN1 |
| platelet-derived growth factor receptor signaling pathway | biological process | PTEN, SRC, PLAT, PTPN11, PTPRJ, JAK2, PIK3C2A, IQGAP1, TXNIP, ZFAND5, PDGFB, PDGFD, PLEKHA1, BCR, CSPG4, ARID5B, BCAR1, TIPARP, RAPGEF1, SMPD3, PDGFA, ABL1, FER, CSRNP1, PDGFRB, PDGFC, PDGFRA, NR4A3, NRP1, RGS14 |
| platelet-derived growth factor receptor-alpha signaling pathway | biological process | PDGFRA |
| platelet-derived growth factor receptor-beta signaling pathway | biological process | LOX, ABL1, PTPN1, CLASP2, PDGFRB, PDGFRL |
| plus-end specific microtubule depolymerization | biological process | KIF19 |
| plus-end-directed vesicle transport along microtubule | biological process | KIF3B, KIF3A, KIF5B, KIFAP3, KIF23, FYCO1, KIF13A |
| PMA-inducible membrane protein ectodomain proteolysis | biological process | ADAM9 |
| PML body organization | biological process | SUMO1, SERBP1, ETS1, HIPK2, PML, HABP4 |
| podosome assembly | biological process | DBNL, BIN2, FARP2, SH3PXD2B |
| pointed-end actin filament capping | biological process | TMOD3, TMOD4, LMOD2, TMOD1, LMOD1 |
| polar body extrusion after meiotic divisions | biological process | WASHC5, SPIRE1, SPIRE2, FMN2 |
| polarity specification of anterior/posterior axis | biological process | SHH |
| polarity specification of proximal/distal axis | biological process | NODAL |
| polarized epithelial cell differentiation | biological process | TP63, DLG5, SCRIB, ZDHHC7 |
| pole plasm assembly | biological process | WDR77 |
| poly(A)+ mRNA export from nucleus | biological process | NXF2, ZC3H11A, NUP93, C12orf50, ENY2, DDX19B, PCID2, MCM3AP, POLDIP3, GLE1, THOC2, NXF1, HHEX, PABPN1, DDX19A |
| poly-N-acetyllactosamine metabolic process | biological process | GAL3ST3 |
| polyadenylation-dependent snoRNA 3'-end processing | biological process | PARN, EXOSC5, EXOSC3, EXOSC4, EXOSC6, EXOSC2 |
| polyamine biosynthetic process | biological process | OAZ3, AMD1, SAT1, ODC1, AZIN1, PAOX, OAZ1, AZIN2, OAZ2, SMS, SRM, SMOX |
| polyamine catabolic process | biological process | SAT1, PAOX, SMOX |
| polyamine homeostasis | biological process | EIF5A2 |
| polyamine metabolic process | biological process | AMD1, SAT1, ODC1, OAZ1, OAZ2, SMS, SRM |
| polyamine transmembrane transport | biological process | ATP13A2 |
| polyketide metabolic process | biological process | IL1B |
| polynucleotide 3' dephosphorylation | biological process | APTX |
| polynucleotide 5' dephosphorylation | biological process | RNGTT, DUSP11 |
| polyol transport | biological process | AQP9 |
| polyphosphate catabolic process | biological process | BNIP2, BNIPL, PRUNE2, PRUNE1, ATCAY |
| polyphosphate metabolic process | biological process | MINPP1 |
| polyprenol catabolic process | biological process | SRD5A3 |
| polysaccharide assembly with MHC class II protein complex | biological process | HLA-DRB1, HLA-DRA |
| polysaccharide biosynthetic process | biological process | NDST1 |
| polysaccharide digestion | biological process | AMY2A, MGAM, SI, LCT |
| polysaccharide localization | biological process | CHST11 |
| polysaccharide metabolic process | biological process | CHST7 |
| polysaccharide transport | biological process | SMPD3 |
| polyubiquitinated misfolded protein transport | biological process | HDAC6 |
| polyuridylation-dependent mRNA catabolic process | biological process | TUT4, DIS3L2, TUT7 |
| pons development | biological process | UQCRQ |
| pons maturation | biological process | GRIN1 |
| pore complex assembly | biological process | BAD, ANO6, CCT3, CCT8, P2RX7, GSDMD, AFDN |
| pore formation in membrane of other organism | biological process | GSDMD |
| pore formation in membrane of other organism during symbiotic interaction | biological process | DEFA1 |
| porphyrin-containing compound biosynthetic process | biological process | PPOX, FECH, UROD, HMBS, ALAD, RSAD1, ABCB6, UROS |
| porphyrin-containing compound metabolic process | biological process | CYP1A1, CYP1A2, ALAS1 |
| positive chemotaxis | biological process | VEGFA, BMP4, CCL5, MIF, HGF, FGF8, SAA1, PTPRJ, CCL16, PDGFB, SAA4, CCL3, DEFB103A, GPNMB, DEFB4A, SCRIB, DEFB104A, HMGB1, SAA2, ANGPT1, VEGFC, SCG2, FGF7, FPR2, VEGFB, PLXNB3, FGF2, NTF3, CORO1A, TSC2, ALKBH1, NRP1, SEMA5A, FGF10, CXCL10, CCL15 |
| positive regulation blood vessel branching | biological process | MDK, ABL1, SIRT6 |
| positive regulation by host of symbiont catalytic activity | biological process | SUGT1 |
| positive regulation by host of viral genome replication | biological process | HSPA8, PPIB, VAPB, STOM, TBC1D20, VAPA |
| positive regulation by host of viral process | biological process | APOE, PPIB, ZNF502, PC, CAV2, CSF1R |
| positive regulation by host of viral release from host cell | biological process | VAPB, ZNF502, PC, CAV2, VAPA |
| positive regulation by host of viral transcription | biological process | SP1, SMARCA4, CCNT1, GTF2B, HPN, TAF11, SMARCB1, EP300, SNW1, LEF1, ZNF639, RRP1B, TFAP4, CTDP1 |
| positive regulation by symbiont of host autophagy | biological process | ULK2, ATG5, ULK1, IRGM |
| positive regulation by virus of viral protein levels in host cell | biological process | STAU1, TBC1D20, HACD3, DDB1 |
| positive regulation of 1-phosphatidylinositol 4-kinase activity | biological process | CD81 |
| positive regulation of 1-phosphatidylinositol-3-kinase activity | biological process | AGAP2, FPR2 |
| positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity | biological process | DGKZ |
| positive regulation of 3'-UTR-mediated mRNA stabilization | biological process | ELAVL4, TENT4B, RBM24, TENT4A |
| positive regulation of abscisic acid-activated signaling pathway | biological process | LANCL2 |
| positive regulation of acetylcholine secretion, neurotransmission | biological process | TACR2, ADORA2A |
| positive regulation of aconitate hydratase activity | biological process | FXN, FTMT, ISCU |
| positive regulation of acrosomal vesicle exocytosis | biological process | HYAL3, ZP3 |
| positive regulation of acrosome reaction | biological process | PLA2G10, POMZP3, GLRA1, CACNA1H, CCDC87, PLB1, ZP3 |
| positive regulation of actin cytoskeleton reorganization | biological process | BAIAP2L1, BAIAP2, STAP1, HAX1, TEK, ABL1, BCAS3, HCLS1, CSF3, HRAS, HCK, CDK5, NTF3, NRP1, FES, BAIAP2L2, CCL27 |
| positive regulation of actin filament binding | biological process | ABL1 |
| positive regulation of actin filament bundle assembly | biological process | PLEK, PFN2, SYNPO, SWAP70, SYNPO2, LIMK1, PFN3, VIL1 |
| positive regulation of actin filament depolymerization | biological process | DSTN, WDR1, PLEK, CFL2, PDXP, VIL1, SEMA5A |
| positive regulation of actin filament polymerization | biological process | ICAM1, MTOR, BAIAP2L1, BAIAP2, CDC42EP5, NCKAP1, NCK1, VASP, KIRREL1, FCHSD2, BAG4, PFN2, CCL11, CTTN, NCK2, CDC42EP2, CDC42EP3, SNX9, CDC42EP4, CDC42EP1, DLG1, GRB2, CRACD, EVL, CCL26, FER, CARMIL1, PRKCE, CSF3, ARF6, CCR7, NCKAP1L, MLST8, PYCARD, HCK, MYO1C, NPHS1, LMOD2, BAIAP2L2, BIN1, LMOD1, PTK2B, FMN1, CCL21 |
| positive regulation of actin filament severing | biological process | CSRP3 |
| positive regulation of actin nucleation | biological process | WIPF3, MAGEL2, SCIN, WIPF1, TIGD5, WIPF2, WAS, FMN1 |
| positive regulation of action potential | biological process | TAC1, SLC9A1, ADRA1A, SCN5A |
| positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process | biological process | CD274 |
| positive regulation of activated T cell autonomous cell death | biological process | LGALS9 |
| positive regulation of activated T cell proliferation | biological process | IL4, IL18, IL23A, IGF2, IL2RA, IGF1, IL2, STAT5B, RPS3, IL12RB1, FADD, IL23R, HMGB1, GPAM, HHLA2, IGFBP2, PYCARD, TNFSF9, ICOSLG, EPO, AGER |
| positive regulation of activation of JAK2 kinase activity | biological process | IL23A, GH1, CCL5 |
| positive regulation of activation of Janus kinase activity | biological process | IL6R, IL23R, AGT |
| positive regulation of activation of membrane attack complex | biological process | C3, C6 |
| positive regulation of activin receptor signaling pathway | biological process | NODAL, CSNK2B, FGF9, ACVR1B, ACVR2B, ACVR2A, ZC3H3 |
| positive regulation of acute inflammatory response | biological process | IL6, IL6ST, TAC1, C2CD4B, OSM, PIK3CG, CREB3L3, OSMR, ADAM8, NPY5R |
| positive regulation of acute inflammatory response to antigenic stimulus | biological process | CNR1 |
| positive regulation of acute inflammatory response to non-antigenic stimulus | biological process | FFAR3 |
| positive regulation of adaptive immune memory response | biological process | CD81 |
| positive regulation of adaptive immune response | biological process | IL6ST, FADD, SKAP1, PYCARD |
| positive regulation of adenosine receptor signaling pathway | biological process | ACPP, CNTN2, NECAB2 |
| positive regulation of adenylate cyclase activity | biological process | WFS1, TIMP2, CACNA1C, HPCA, CACNA1D, AKAP5, CALCR, NF1, STIM1 |
| positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | biological process | MRAP2 |
| positive regulation of adherens junction organization | biological process | PTPN23, ADD1 |
| positive regulation of adiponectin secretion | biological process | C1QTNF3, HCAR2 |
| positive regulation of adipose tissue development | biological process | NR1H4, SORL1, TRPM4, SH3PXD2B |
| positive regulation of aggrephagy | biological process | BAG3, HSPB8, HTT |
| positive regulation of aldosterone biosynthetic process | biological process | WNT4, BMP6 |
| positive regulation of aldosterone secretion | biological process | C1QTNF1, BMP6 |
| positive regulation of alkaline phosphatase activity | biological process | MEF2C, ITGA2, GPLD1, PPARGC1B, SMAD3 |
| positive regulation of alpha-beta T cell differentiation | biological process | SHH, GLI3, SYK, PNP, ITPKB, ZAP70, NKAP, ADA, IHH |
| positive regulation of alpha-beta T cell proliferation | biological process | SYK, ZAP70, PTPRC, CD3E, RIPK2, TNFSF4, CD28, EBI3 |
| positive regulation of amacrine cell differentiation | biological process | DLX1, DLX2 |
| positive regulation of amino acid transport | biological process | CLTRN |
| positive regulation of aminoacyl-tRNA ligase activity | biological process | AIMP2 |
| positive regulation of ammonia assimilation cycle | biological process | NR1H4 |
| positive regulation of AMPA glutamate receptor clustering | biological process | ZDHHC2, SSH1 |
| positive regulation of AMPA receptor activity | biological process | CACNG2, CACNG3, ADRB2, CACNG4, RELN |
| positive regulation of amyloid fibril formation | biological process | PSEN1 |
| positive regulation of amyloid precursor protein biosynthetic process | biological process | PAWR, SOAT1, ABCA2 |
| positive regulation of amyloid precursor protein catabolic process | biological process | ROCK2, SPON1, ABCA2 |
| positive regulation of amyloid-beta clearance | biological process | ROCK1, LRPAP1, TREM2, LRP1, ABCA7 |
| positive regulation of anaphase-promoting complex-dependent catabolic process | biological process | FZR1, CDC20B |
| positive regulation of androgen receptor activity | biological process | PARK7, RWDD1, BUD31, TAF1 |
| positive regulation of androgen secretion | biological process | NKX3-1 |
| positive regulation of angiogenesis | biological process | IL1B, CXCL8, VEGFA, NOS3, ADM, BRCA1, HIF1A, SERPINE1, HMOX1, FLT1, KDR, NODAL, C3, IL1A, HSPB1, F3, PGF, CCL5, HGF, GATA4, CYP1B1, NTRK1, ECM1, CX3CL1, ERAP1, ISL1, CCBE1, DDAH1, ZC3H12A, EMC10, RTN4, BTG1, CYBB, XBP1, AGGF1, TNFSF12, ANXA3, C6, TIE1, PRKD1, RRAS, CD34, CCL11, HIPK1, MYDGF, RAMP2, RLN2, CHI3L1, RUNX1, THBS1, TEK, VASH2, HMGA2, ANGPTL3, ETS1, CXCR2, CHRNA7, ANGPT4, PRKCB, PDCD6, HIPK2, GAB1, TWIST1, PTGIS, AGO2, ANGPT2, CX3CR1, VEGFC, LRG1, GATA2, ITGB8, HK2, SASH1, ITGAX, EPHA1, CXCR3, C3AR1, ANGPTL4, FGF18, ITGB2, GRN, AQP1, SFRP2, PAK4, CDH5, TGFBR2, PRKD2, SMOC2, RAPGEF3, JUP, APLNR, VEGFB, TLR3, FGF2, ENG, ACVRL1, NRP1, PDPK1, CTSH, PIK3R6, GDF2, TBXA2R, CD40, ADAM12, FGF1, CCR3, PTK2B, STIM1, SEMA5A, GREM1, C5AR1 |
| positive regulation of anion channel activity | biological process | TCAF1 |
| positive regulation of anoikis | biological process | PTRH2, CRYBA1, TLE5, MYBBP1A, SIK1, BRMS1 |
| positive regulation of anterior head development | biological process | SSBP3, LHX1 |
| positive regulation of anterograde axonal transport of mitochondrion | biological process | FEZ1 |
| positive regulation of anterograde dense core granule transport | biological process | MAP2, TRIM46 |
| positive regulation of anterograde synaptic vesicle transport | biological process | BORCS5, MAP2 |
| positive regulation of antibacterial peptide production | biological process | PGC, KLK5, KLK7 |
| positive regulation of antifungal innate immune response | biological process | PLA2G5 |
| positive regulation of antigen processing and presentation of peptide antigen via MHC class I | biological process | ABCB1 |
| positive regulation of antigen processing and presentation of peptide antigen via MHC class II | biological process | TREM2, PYCARD |
| positive regulation of antigen receptor-mediated signaling pathway | biological process | PTPRC |
| positive regulation of antral ovarian follicle growth | biological process | ZP3 |
| positive regulation of aorta morphogenesis | biological process | NOTCH1, EFNB2 |
| positive regulation of aortic smooth muscle cell differentiation | biological process | CTH |
| positive regulation of apoptotic cell clearance | biological process | C3, CD300LF, C2, CCL2 |
| positive regulation of apoptotic DNA fragmentation | biological process | BAX, ENDOG |
| positive regulation of apoptotic process | biological process | SOD1, TGFB1, TNF, IL1B, TP53, IL6, TGFB3, MMP9, WT1, FAS, ADM, PTGS2, TNFSF10, BAX, BAK1, HIF1A, ESR2, AKT1, CASP3, FASLG, GSK3B, CASP9, ATM, CDKN2A, ITGB1, CLU, BMP7, CTNNB1, PTEN, BAD, IGF2R, BMP4, SRC, ITGA6, MAPK8, C1QBP, PDCD1, NGF, HSPD1, PPARG, SOS1, FOXO1, CYP1B1, DUSP6, DNM1L, ALDH1A2, TOP2A, ADCY10, 38231, LDHA, ANXA5, CCN1, GADD45B, ARL6IP5, IAPP, RPS6, SIAH1, DDX3X, JAK2, TNFAIP8, STK3, C3orf38, SHQ1, CTNNBL1, PAWR, OLFM1, ARHGEF3, SPHK2, BCLAF1, FZD9, KALRN, PDCD2, TXNIP, SCIN, TNFRSF10C, BCL10, RARB, BCL6, GRIN1, STK4, ARHGEF7, TCTN3, APH1B, ZMAT3, PSENEN, UTP11, PDCD5, ARHGEF11, EEF1E1, BCL2L11, HOXA5, PTN, SNCA, RPS27A, RACK1, PHLDA2, DAB2IP, TP53INP1, OMA1, SUDS3, TOMM22, MAP3K20, STK17A, VAV3, SAP18, NEURL1, STK17B, MLLT11, ANO6, CAMK1D, JMY, CSRNP3, APH1A, HTRA2, ANXA1, MCF2, IDO1, MNDA, FOXA1, ABR, ITGB3BP, ARHGEF6, RYBP, WDR35, UBD, ARHGEF9, BNIP3L, NUPR1, SMPD1, ARHGEF5, ZNF268, CCAR1, FRZB, ARHGEF4, ACIN1, TNFRSF10B, CTLA4, SLC9A1, NOTCH1, REST, ENDOG, APBB2, HRK, HPGD, PRMT2, ID3, PPID |
| positive regulation of apoptotic process by virus | biological process | BAD, BCL2L11 |
| positive regulation of apoptotic process involved in mammary gland involution | biological process | VDR, BAX, PML |
| positive regulation of apoptotic process involved in morphogenesis | biological process | NOTCH1 |
| positive regulation of apoptotic signaling pathway | biological process | PTEN, TP63, TRIM39, MAGED1, DAB2IP, NKX3-1, RPS3, CTSC, CASP2, BID, MAPK9, TPD52L1, TRAF7, PML, TGFBR1, PRKCD, INCA1, NFATC4, NGFR, CTSH, ADORA2A, ING5, CRADD |
| positive regulation of appetite | biological process | GHRL, GHSR, NPY |
| positive regulation of arachidonic acid secretion | biological process | MIF, PLA2G6, PLA2G10, PLA2R1, AVPR1B, SSTR4, NTSR1 |
| positive regulation of ARF protein signal transduction | biological process | MAP4K4 |
| positive regulation of Arp2/3 complex-mediated actin nucleation | biological process | WASL, WASF3, NCKAP1, FCHSD2, ABI2, WASF2, CYFIP1, WASF1, WAS |
| positive regulation of artery morphogenesis | biological process | RTN4, MDK |
| positive regulation of aspartate secretion | biological process | SLC12A2, ABAT |
| positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | biological process | EFNA1, ROCK2, PICALM, LYN, EPHA4, EFNA3, AGER |
| positive regulation of aspartic-type peptidase activity | biological process | GRN |
| positive regulation of astrocyte activation | biological process | TTBK1 |
| positive regulation of astrocyte differentiation | biological process | IL1B, LIF, IL6ST, PRPF19, HES1, NOTCH1, ID2, BMP2, MAG, BIN1, CLCF1 |
| positive regulation of ATP biosynthetic process | biological process | STAT3, PPARGC1A, PID1, PINK1, MT-CO2, TREM2, SLC25A12 |
| positive regulation of ATP-dependent microtubule motor activity, plus-end-directed | biological process | DYNC1I1, DYNC1I2, DNAL4, WDR60, DYNLL2 |
| positive regulation of ATPase activity | biological process | HSPA2, TPM1, TOR1AIP1, DNAJC10, DNAJB11, RGN, DNAJA2, DNAJB4, MYL4, RAB4A, DNAJC1, PFN2, DNAJC15, MYBPC3, DNAJC19, ALDOB, DNAJC24, AHSA1, CHTOP, TOR1AIP2, DNAJB1, GABARAPL2, NAPA, DNAJC9, ATP1B1, GTF2H4, ATP1B2, DNAJB2, ATP1B3, MYL3, HSCB, FGF10, ATP4B |
| positive regulation of atrial cardiac muscle cell action potential | biological process | TRPM4 |
| positive regulation of attachment of mitotic spindle microtubules to kinetochore | biological process | HNRNPU, BECN1 |
| positive regulation of attachment of spindle microtubules to kinetochore | biological process | CCNB1, RCC2, SIRT2 |
| positive regulation of autophagosome assembly | biological process | SH3GLB1, ULK1, PIP4K2A, ELAPOR1, RALB, RAB3GAP2, PIP4K2C, PIP4K2B, RAB3GAP1, LRSAM1 |
| positive regulation of autophagosome maturation | biological process | ADRB2, CALCOCO2, UVRAG, IRGM, SMCR8, CLEC16A, FYCO1 |
| positive regulation of autophagy | biological process | IFNG, DCN, HIF1A, BAD, MEFV, FOXO1, OPTN, PLK2, SH3BP4, PIK3C2A, ZC3H12A, SH3GLB1, XBP1, TRIM58, NPRL2, TP53INP1, PRKD1, TMEM59, TRIM8, ROCK1, ULK1, HMGB1, DHRSX, BNIP3, KAT5, TRIM38, SVIP, IRGM, PRKAA2, FLCN, DAPK1, MID2, TRIM65, TRIM21, RNF152, PIM2, FOXO3, TFEB, PLEKHF1, AMBRA1, TPCN1, LRRK2, TRIM6, TRIM5, TICAM1, TRIM22 |
| positive regulation of autophagy in response to ER overload | biological process | BCL2L11 |
| positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | biological process | ATP5IF1, PINK1, HK2, MUL1 |
| positive regulation of axon extension | biological process | GSK3B, SEMA7A, NRG1, FN1, SHTN1, ISLR2, RAB11A, MACF1, CTTN, ADNP, DISC1, NTN1, DBNL, TRPV2, GOLGA4, MAP3K13, RUFY3, CDKL5, CYFIP1, HCLS1, TNFRSF12A, LRP1, POU4F2, ILK, TRPC5, SRF, TWF2, CDH4, L1CAM, LIMK1, ANAPC2, MAP1B, GDI1 |
| positive regulation of axon extension involved in axon guidance | biological process | VEGFA, BMPR2, MEGF8, DSCAM, NRP1, CXCL12, SEMA5A |
| positive regulation of axon extension involved in regeneration | biological process | LRP1 |
| positive regulation of axon regeneration | biological process | PTN, FKBP1B, GRN, SCARF1, CNTF |
| positive regulation of axonogenesis | biological process | ZEB2, ARHGDIA, NGF, SKIL, NIN, STK25, PLXNC1, SEMA4D, ROBO2, NTRK2, TRAK1, SLITRK1, TIAM1, METRN, PLXNA1, CYFIP1, MAP6, PLXNA4, MAP2K1, ILK, PLXNB3, NGFR, PLXNA3, PLXNB2, PLXNB1, PLXNA2, AMIGO1, PLXND1, SLIT2, TIAM2, ROBO1, NEFL |
| positive regulation of B cell activation | biological process | IL4, IL6, PELI1, CD81, NOD2, IGLL5, TNFSF4, TLR9, IGLL1, TNIP2, SH3KBP1, TICAM1 |
| positive regulation of B cell apoptotic process | biological process | IL10, BAX, FNIP1 |
| positive regulation of B cell chemotaxis | biological process | PTK2B |
| positive regulation of B cell differentiation | biological process | BAD, IL7, XBP1, STAT5B, SYK, PCID2, MMP14, BTK, NCKAP1L, INPP5D |
| positive regulation of B cell proliferation | biological process | IL4, BCL2, TLR4, IL5, MIF, IL2, IL21, CD38, CD74, GPR183, IL7, BCL6, PELI1, CD81, VAV3, TFRC, IL13, ATAD5, WNT3A, MEF2C, SLC39A10, IRS2, TIRAP, NFATC2, PTPRC, TNFRSF4, TNFSF13B, ADA, CDKN1A, TLR9, NCKAP1L, BST1, TNFRSF13C, CHRNB2, CD40, CARD11, CLCF1, TICAM1 |
| positive regulation of B cell receptor signaling pathway | biological process | PRKCH, CD81, CMTM3, STAP1, FOXP1, SLC39A10, PRKCB, NFAM1 |
| positive regulation of B cell tolerance induction | biological process | TGFBR2 |
| positive regulation of base-excision repair | biological process | RPS3 |
| positive regulation of basement membrane assembly involved in embryonic body morphogenesis | biological process | PHLDB1, PHLDB2, CLASP2, DAG1, CLASP1 |
| positive regulation of behavior | biological process | STRA6 |
| positive regulation of behavioral fear response | biological process | GJA1, CRH, MEF2C, UCN, CCK, PENK |
| positive regulation of beta-amyloid formation | biological process | APOE, CLU, IFNGR1, EFNA1, ROCK2, ABCG1, PICALM, RELA, CHRNA7, SLC2A13, GSAP, EPHA4, ABCA2, TNF |
| positive regulation of bicellular tight junction assembly | biological process | CLDN5, EPHA2, CLDN1 |
| positive regulation of bile acid biosynthetic process | biological process | STAR, NR1D1, STARD4 |
| positive regulation of bile acid secretion | biological process | ABCB11 |
| positive regulation of binding | biological process | PON1, ENO1, ANXA2, DPH3, S100A10, RARA |
| positive regulation of biomineral tissue development | biological process | ATF4, ODAPH |
| positive regulation of bleb assembly | biological process | ANLN, P2RX7 |
| positive regulation of blood coagulation | biological process | SERPINE1, NFE2L2, F2R, S100A9, HPSE, F7, THBS1, F12, DMTN, F2, TBXA2R, APOH, CD36 |
| positive regulation of blood microparticle formation | biological process | TNF, CD36 |
| positive regulation of blood pressure | biological process | TACR3, OXTR, OXT, ADH5, ATP5PF, QRFP, CYBA, CNR1, GLP1R, F11R, NPFF, ADRA2B, AVPR2, ID2, CARTPT, TBXA2R, GRIP2, AGT |
| positive regulation of blood vessel diameter | biological process | KCNMB1, PPARD, UCN, SCPEP1, PTPRM, CALCA, GJA5, NPPC, PTAFR, INS, AGT, GPER1 |
| positive regulation of blood vessel endothelial cell migration | biological process | TGFB1, VEGFA, AKT1, HSPB1, MAPK14, ATP5F1B, PDGFB, PRKD1, AMOT, THBS1, NUS1, MAP2K3, HMGB1, ETS1, ANGPT4, ANGPT1, VEGFC, GATA2, FGF18, PLG, PRKD2, FGF2, P2RX4, PDPK1, CD40, STAT5A, AMOTL1 |
| positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | JCAD, AGTR1, PPP1R16B, GATA2, APLNR, FGFBP1 |
| positive regulation of blood vessel remodeling | biological process | TMBIM1, HRG |
| positive regulation of blood-brain barrier permeability | biological process | TJP1, ANGPT1 |
| positive regulation of BMP signaling pathway | biological process | BMP4, BMPR2, GATA4, CCN1, SMAD4, ELAPOR2, HES1, PELO, NOTCH1, MSX1, SOX11, RNF165, RBPJ, NUMA1, TWSG1, SMAD2, ILK, CDH5, MSX2, FKBP8, ZNF423, CRB2, SULF1, ENG, ACVRL1, GPC3, GDF2, UBE2O, GDF5 |
| positive regulation of bone development | biological process | TAPT1 |
| positive regulation of bone mineralization | biological process | TGFB1, TGFB3, BMP7, BMP4, BMPR2, CCN1, FZD9, FBN2, NELL1, PTN, ACVR1, ANO6, BMPR1A, ATRAID, WNT4, GPM6B, ACVR2B, ADRB2, MEF2C, FAM20C, ISG15, TFAP2A, SLC8A1, ADGRV1, ALOX5, BMP6, ACVR2A, P2RX7, WNT10B, BMP2, ATP2B1, KL, PKDCC, SMAD3, OSR2 |
| positive regulation of bone mineralization involved in bone maturation | biological process | LTF |
| positive regulation of bone resorption | biological process | FSHB, CA2, SPP1, TFRC, SYK, TMEM64, DEF8, ATP6AP1, LTBP3, TNFRSF11A, ADAM8, PPARGC1B, DCSTAMP |
| positive regulation of brain-derived neurotrophic factor receptor signaling pathway | biological process | BDNF, SLC2A4 |
| positive regulation of branching involved in lung morphogenesis | biological process | CTNNB1, BMP4 |
| positive regulation of branching involved in ureteric bud morphogenesis | biological process | TGFB1, VEGFA, SOX9, GDNF, LGR4, MAGED1, PAX8, WNT2B, LHX1, SMO, HOXB7, SIX1, SIX4, AGT, GREM1 |
| positive regulation of branching morphogenesis of a nerve | biological process | MAP3K13 |
| positive regulation of brown fat cell differentiation | biological process | PTGS2, MAPK14, HNRNPU, FNDC5, NAPEPLD, TFE3, RREB1, SIX1, PRDM16, INS, METRNL, ZBTB7B |
| positive regulation of C-C chemokine receptor CCR7 signaling pathway | biological process | TREM2 |
| positive regulation of calcidiol 1-monooxygenase activity | biological process | TNF, IFNG, IL1B |
| positive regulation of calcineurin-NFAT signaling cascade | biological process | CIB1, IGF1, NRG1, CHP2, CHERP, LMCD1, SLC9A1, STIMATE, CAMTA1, ERBB3, SPPL3, CEFIP, TNF, AKAP6 |
| positive regulation of calcium ion import | biological process | SPHK2, PDGFB, CCL3, CRH, UCN, TRPV2, CASK, GRM6, PDGFRB, TRPV3, ATP2C2, CXCL12, CCL2 |
| positive regulation of calcium ion import across plasma membrane | biological process | IAPP, RAMP3, CALCR |
| positive regulation of calcium ion import into sarcoplasmic reticulum | biological process | ATP2A1 |
| positive regulation of calcium ion transmembrane transport | biological process | GJC2 |
| positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | biological process | CACNB2 |
| positive regulation of calcium ion transmembrane transporter activity | biological process | ANK2 |
| positive regulation of calcium ion transport | biological process | EDNRA, CCL5, F2R, WFS1, WNK3, CCR1, LILRA5, CCL3, CREB3, MCHR1, CRACR2A, STIM2, ANK2, HOMER1, LILRA2, LPAR3, FFAR1, HCRT, ATP2B1, CACNA1D, P2RX4, ARRB2, MYLK, CAMK2A, CACNB2 |
| positive regulation of calcium ion transport into cytosol | biological process | BAX, BAK1, BMP4, GRIN1, TRPC3, PLA2G1B, ASPH, P2RX7, CD4, ADCYAP1R1, P2RX4, P2RX5, P2RX3, P2RX2, CAV1 |
| positive regulation of calcium ion-dependent exocytosis | biological process | SYT1, ARF1, KCNB1, CACNA1G, CACNA1I, CDK5R2, CACNA1H, CDK5, SYT9, CLTRN, SYT7, DOC2B, SYT10 |
| positive regulation of calcium ion-dependent exocytosis of neurotransmitter | biological process | SYT1 |
| positive regulation of calcium-dependent cell-cell adhesion | biological process | KIFAP3 |
| positive regulation of calcium-independent cell-cell adhesion | biological process | CX3CL1 |
| positive regulation of calcium-mediated signaling | biological process | CD8A, HINT1, CCL3, SYK, ZAP70, CD3E, ADA, TREM2, CD4, CDH13, P2RX4, P2RX5, P2RX3, P2RX2, TRAT1 |
| positive regulation of calcium-transporting ATPase activity | biological process | HSPA2, SUMO1, RGN, RYR2, ATP2A1 |
| positive regulation of calcium:sodium antiporter activity | biological process | SLC9A1, ATP1B1 |
| positive regulation of CAMKK-AMPK signaling cascade | biological process | TREM2 |
| positive regulation of cAMP biosynthetic process | biological process | ADM, INSL3, GNAS, RXFP2 |
| positive regulation of cAMP-dependent protein kinase activity | biological process | RAPGEF2, ADIPOQ, ADRB2 |
| positive regulation of cAMP-mediated signaling | biological process | LHCGR, GNAS, RAPGEF2, CRH, GIPR, UCN, GPR61, CGAS, SCT, ADCYAP1R1, SCTR |
| positive regulation of canonical Wnt signaling pathway | biological process | FGFR2, SRC, PSMA3, FGF9, PSMB1, PSMB5, PSMC2, PSMA8, USP47, DDX3X, PSMA7, UBR5, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PPP2R3A, BAMBI, PSMB7, FZD9, PPM1B, XIAP, PSMD6, PSMD1, PSMD14, PSMD7, PTK7, PIN1, ADGRA2, LGR4, PSMB6, WLS, PSMD10, TNKS, PSMD8, PSMC5, GPC5, SCEL, PSMB4, PSME1, ASPM, PSMB8, PSMD4, GSKIP, PSMC3, WNT3A, PSMA6, LYPD6, WNK1, CSNK1D, PLEKHA4, WNK2, AXIN1, RSPO2, TTC21B, TNKS2, CCAR2, PSMD12, PSMB9, PSMC4, RUVBL1, PSMD9, PSMA4, CSNK1G2, PSMD2, GID8, CSNK1G1, PPM1A, YAP1, SOX4, PSMD5, USP34, NRARP, PSMF1, TBL1X, PSMB3, FAM53B, RSPO3, DACT1, GPRC5B, DLX5, ILK, AMER1, SFRP2, ZBED3, PSMD3, PSMC1, DAAM2, EDA, NLE1, AXIN2, ARNTL, WNT10B, JUP, SMURF2, CTDNEP1, SFRP4, TRPM4, ZBED2, RNF146, LGR5, JRK, CDH3, GPC3, CAPRIN2, LGR6, ROR2, PRDM15, SMAD3, LRRK1, SULF2, DKK2, RECK, SEMA5A, LRRK2, VPS35, PSMD13, FGF10, PSMB10, CAV1 |
| positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment | biological process | RBPJ |
| positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation | biological process | WNT3A |
| positive regulation of cap-dependent translational initiation | biological process | NCK1 |
| positive regulation of cap-independent translational initiation | biological process | NCK1, YTHDF2 |
| positive regulation of cardiac endothelial to mesenchymal transition | biological process | GATA5 |
| positive regulation of cardiac epithelial to mesenchymal transition | biological process | NOTCH1, JAG1 |
| positive regulation of cardiac muscle cell apoptotic process | biological process | CAMK2D, CAPN2, LTK, HMGCR, CXCR2, BNIP3, MAP3K5, POU4F2, TIGAR, AGT, CAMK2A, TP53 |
| positive regulation of cardiac muscle cell contraction | biological process | ATP2A1 |
| positive regulation of cardiac muscle cell differentiation | biological process | TGFB1, NRG1, WNT3A, MEF2C, MYOCD, EFNB2, KAT2A, ARRB2, GREM1 |
| positive regulation of cardiac muscle cell proliferation | biological process | CDK1, CCNB1, FGFR2, FGFR1, NRG1, FGF9, MAPK14, ZFPM2, BMPR1A, NOTCH1, MEF2C, TBX5, RBPJ, YAP1, HEY2, TBX20, GLI1, FGF2, TBX2 |
| positive regulation of cardiac muscle contraction | biological process | HSP90AA1, ACE2, CCN2, ADRA1A, UCN, RGS2 |
| positive regulation of cardiac muscle fiber development | biological process | BMP4 |
| positive regulation of cardiac muscle hypertrophy | biological process | IL6ST, PARP1, IGF1, CDK9, CAMK2D, PTK2, ROCK2, SLC9A1, PDE9A, ROCK1, ADRA1A, PPP3CA, PDE5A, EDN1, NR4A3, AGT, HAND2 |
| positive regulation of cardiac muscle hypertrophy in response to stress | biological process | TRPC3, PPP3CA |
| positive regulation of cardiac muscle myoblast proliferation | biological process | ATF2, MEIS2 |
| positive regulation of cardiac muscle tissue development | biological process | ERBB3 |
| positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | biological process | SEMA3C |
| positive regulation of cardiac vascular smooth muscle cell differentiation | biological process | MYOCD, GPER1 |
| positive regulation of cardiac ventricle development | biological process | BMPR1A |
| positive regulation of cardioblast differentiation | biological process | GATA4, DHX36, TGFB2, TBX5, NKX2-5 |
| positive regulation of cardiolipin metabolic process | biological process | STOML2 |
| positive regulation of cartilage development | biological process | SOX9, BMP4, BMPR2, SOX5, CCN1, MDK, BMP1, TAPT1, SOX6, BMP2, ZBTB16, GDF2 |
| positive regulation of catalytic activity | biological process | SOD1, BCL2, DNMT3L, IGF2, CASP3, CIB1, ALOX5AP, FXN, DBF4, CYB5B, XRCC5, CWF19L1, APH1B, MGST2, PSENEN, PRKRA, GTF2F1, APH1A, SLX4, NUPR1, NOXO1, WNT9B, MMP15, ARF1, NOXA1, DCP1B, NSMAF, CLPS, CTSA, DDOST, NR4A2, PSEN1, AZIN1, MMP16, RAB3GAP2, APOC1, ATP7A, KRTCAP2, AZIN2, CXCL1, YWHAB, WRNIP1, BCAS3, PIK3CG, PRKCE, LTC4S, P2RX7, DCP1A, MT3, GMFB, DPM2, NCF4, PPP1R12B, TRIM23, PSEN2, DAD1, STX4, PHACTR4, GMFG, FGFR4, SH3PXD2B, MMP17, B3GAT3, SH3PXD2A, AGT, APOBEC1, PITRM1, SAE1, RFC1, GTF3C4, LRCOL1, CAV1 |
| positive regulation of catecholamine secretion | biological process | GRK2, PINK1, KCNB1 |
| positive regulation of catenin import into nucleus | biological process | EGFR, EGF, KANK1 |
| positive regulation of cation channel activity | biological process | ANK3, ACTN2, ANK2, CTSS, NTSR1 |
| positive regulation of caveolin-mediated endocytosis | biological process | CAV3, NEDD4L, CLN3, ITSN1 |
| positive regulation of CD4-positive, alpha-beta T cell activation | biological process | CD55 |
| positive regulation of CD4-positive, alpha-beta T cell costimulation | biological process | TNFSF4 |
| positive regulation of CD4-positive, alpha-beta T cell differentiation | biological process | CD83, SOCS1, TNFSF4, NCKAP1L, ZBTB7B |
| positive regulation of CD4-positive, alpha-beta T cell proliferation | biological process | CD55, LGALS9, CD81, TGFBR2 |
| positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response | biological process | IFNG, LGALS9 |
| positive regulation of CD40 signaling pathway | biological process | TREM2 |
| positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation | biological process | FADD |
| positive regulation of CD8-positive, alpha-beta T cell differentiation | biological process | CBFB, RUNX1, NCKAP1L |
| positive regulation of CD8-positive, alpha-beta T cell proliferation | biological process | HLA-E, PTPN22 |
| positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity | biological process | SERINC1, SERINC5, SERINC2 |
| positive regulation of cell activation | biological process | CCN2, JAK2, LILRA5, LILRA2 |
| positive regulation of cell adhesion | biological process | TNF, IFNG, VEGFA, IL12A, ERBB2, ITGAV, SRC, CCL5, NRG1, C1QBP, TPM1, SAA1, CX3CL1, PTPRJ, CYTH3, P4HB, VAV3, STX3, BAG4, RHOD, MDK, ZFHX3, ITGA2, SKAP1, ANGPT1, PPP3CA, TFE3, EPB41L4B, FLCN, TGM2, TNFRSF18, TMEM102, CHRD, CCR7, FUT7, PREX1, PRKD2, AZU1, STX4, FRMD5, DYSF, VAV1, ADAM8, CXCL12, DUSP26 |
| positive regulation of cell adhesion mediated by integrin | biological process | CIB1, IFT74, SYK, PTPN6, FERMT1, P2RY12, TGFB2, ADAM9, FOXC2, SFRP2, RET, NCKAP1L, RAC3, CCL21 |
| positive regulation of cell adhesion molecule production | biological process | IL1B, COLEC12, FLOT1, CAV1 |
| positive regulation of cell aging | biological process | TP53 |
| positive regulation of cell communication by chemical coupling | biological process | GJA1, GJA5 |
| positive regulation of cell communication by electrical coupling | biological process | ANK3 |
| positive regulation of cell communication by electrical coupling involved in cardiac conduction | biological process | TRDN |
| positive regulation of cell cycle | biological process | CCNB1, FGFR2, MDM2, FGFR1, CCPG1, BCL2L11, HCFC1, NUPR1, TGM1, SRPK2, CCND1, TRIM32, PGGT1B, LRP6, ASCL1, STOX1, ANKRD17, TGFB2, RPS15A, GDPD5, SLC6A4, CDKN1B, FOXG1, C6orf89, CITED2, TBX3, TRIM21, NR4A3, PROX1, PTK6, CALR, FLT3LG, RARA |
| positive regulation of cell cycle arrest | biological process | TGFB1, TP53, BRCA1, CDKN2A, DAB2IP, PKD2, CRLF3, HMGA2, MED25, UHRF2, CDK5R1, INSM1, RGCC, POU4F1, ID2, RPL23, MYOG, FOXO4, ZBTB17, MYBBP1A, RIPOR2 |
| positive regulation of cell cycle checkpoint | biological process | PROX1 |
| positive regulation of cell cycle G1/S phase transition | biological process | TP63, STXBP4, PAF1, FAM83D, PHB2, CDC73, PAGR1, GLI1, DDRGK1 |
| positive regulation of cell cycle G2/M phase transition | biological process | NPM1, DYRK3, ATAD5, CDC25B |
| positive regulation of cell cycle process | biological process | NUDT16, LEF1 |
| positive regulation of cell death | biological process | IL1B, FAS, PTGS2, BMP7, AKR1C3, MTOR, BMP4, DUSP6, KATNB1, MYCN, PRNP, IAPP, CCN2, TRIM13, ZC3H12A, KCNK2, BCL2L11, NKX3-1, CRH, SLFN11, DKK1, AIFM1, PDX1, HBB, APC, CDKN1B, RIPK2, FAF1, CDKN1A, LPAR1, RAMP3, HPR, MT3, LRP1, HP, SAP30BP, AXIN2, CALCR, HBA1, CIDEB, NOD1, PRR7, ACOX2, ACER2, CD36 |
| positive regulation of cell development | biological process | HOXA11 |
| positive regulation of cell differentiation | biological process | AR, CLU, BMP7, BMP4, SOX2, SHH, NF2, GDNF, CCN1, CCN2, JAK2, ISL1, NKX2-2, PTN, ZNF268, SERPINF2, GATA3, NEUROD4, NEUROD1, INSM1, JUNB, RPS6KA1, MAP2K1, POU4F2, SRF, BTC, CDX2, BMP2, VHL, JUND, DLX1, INS, HSF4, WNT9A, EDN3, SOCS3, DLX2, PPP1R13L |
| positive regulation of cell division | biological process | TGFB1, IL1B, TGFB3, VEGFA, IGF2, FGFR2, IL1A, PGF, CAT, FGF8, SHH, FGF3, FGF9, PROK1, PDGFB, TGFA, PTN, NKX3-1, PDGFD, YBX1, MDK, SIRT2, HDGF, FGF5, EREG, PDGFA, ITGB1BP1, TGFB2, VEGFC, CSPP1, OSM, FGF7, BTC, GAREM1, PPBP, FGF6, VEGFB, PDGFC, FGF2, THBS4, FGF1, GKN1, HTR2B, MACC1 |
| positive regulation of cell fate commitment | biological process | SPDEF |
| positive regulation of cell fate specification | biological process | FGF2 |
| positive regulation of cell growth | biological process | EGFR, BCL2, ERBB2, AKT1, CIB1, IGF1, IL2, NRG1, CDC42, S100A9, USP47, DERL2, DDX3X, CD38, EIF4G2, FXN, SLC44A4, SUPV3L1, EXOSC9, SLC25A33, TAF9B, LGI1, IGFBP1, PSMD10, KLHL22, ADNP2, CXCL16, NCBP1, CEP43, SLC9A1, DNPH1, HPN, CYBA, TRIM32, UCN, TGFB2, CSNK2A1, DDX49, SDCBP, MMP14, SFN, MFSD2A, ACSL4, TGFBR1, EXOSC4, S100A8, KRT17, RPS6KA1, FAM122A, HBEGF, LEF1, H1-5, SFRP2, CDKN2AIP, ZNF639, AVP, MAP2K5, BRAT1, EXTL3, CRK, EXOSC2, INO80, F2, INS, RPTOR, HDGFL2, PTK2B, N6AMT1, H3-3A, AKAP6 |
| positive regulation of cell growth involved in cardiac muscle cell development | biological process | MTOR, PIN1, DDX39B, HAMP, EDN1, AKAP6 |
| positive regulation of cell junction assembly | biological process | FLOT1 |
| positive regulation of cell migration | biological process | EGFR, F10, TGFB1, CGA, FSHB, VEGFA, FLT1, MAPK1, KDR, CIB1, SEMA7A, ITGB1, ITGA5, F3, IGF1, INSR, ITGAV, IGF1R, KIT, HSPA5, BMP4, CCL5, HGF, PLAU, FN1, F2R, AIF1, CSF1, CX3CL1, CCN1, SEMA3E, SEMA6D, JAK2, CXCR4, PDCD10, CCR1, TJP1, CPNE3, GNAI2, TDGF1, PIK3R1, SEMA3F, PDGFB, TMSB15B, XBP1, NUMB, RACK1, CEMIP, CCL3, TNFAIP6, ACVR1, PTK2, SEMA4C, PDGFD, CXCL16, CREB3, ROCK2, F7, CCL11, DAB2, GPNMB, MAZ, ZNF268, CCAR1, SEMA3G, SEMA4G, RHOD, CEP43, S1PR1, NOTCH1, BCAR1, SEMA4D, PTP4A1, CD274, MAP4K4, THBS1, MDK, TRIM32, LAMC2, HAS2, IRS2, TCAF2, DIAPH1, CD151, RRAS2, GCNT2, ELP5, ANGPTL3, ADRA2A, ETS1, CEACAM6, GRB7, SMO, ONECUT2, PDGFA, NEDD9, SMIM22, APC, TIAM1, RUFY3, ARHGEF39, MIEN1, SYNPO2, SDCBP, MMP14, INSM1, PPP3CA, CCL26, FER, SERPINB3, ACTG1, PIK3R3, LYN, RDX, TGFBR1, VEGFC, CARMIL1, CBLL1, FAM89B, SH3RF2, MYADM, HBEGF, SEMA6A, GTSE1, LEF1, ATP8A1, ITGAX, EPHA1, MAPRE1, FAM83H, PODXL, SPRY2, WNT11, LAMB1, GLI1, FGR, GRN, ILK, TRADD, PDPN, RET, PDGFRB, DRD1, CDH5, CDH13, SEMA3B, PREX1, SEMA3C, SEMA6C, ZN |
| positive regulation of cell migration by vascular endothelial growth factor signaling pathway | biological process | GAB1, MYO1C |
| positive regulation of cell migration involved in sprouting angiogenesis | biological process | VEGFA, PTGS2, CIB1, PLK2, PIK3C2A, JCAD, HDAC9, ANXA1, SRPX2, MAP3K3, ABL1, HDAC7, FOXC2, GATA2, FGFBP1, RHOJ, FGF2, NRP1 |
| positive regulation of cell motility | biological process | EPCAM, PHPT1, SPOCK2, NTN1, TRIM32, SLC26A5, TWIST1, DUOXA2, CCL19, DUOX2, CCR7, CFAP20, CLDN7, CSF1R, AKT2, CAVIN1, DUOX1, C1QTNF8, CCL21 |
| positive regulation of cell projection organization | biological process | RAB8B, PLEK2, ITGA2, KAT2A, PROM2 |
| positive regulation of cell proliferation | biological process | EGFR, TIMP1, EGF, TGFB1, CGA, FSHB, IFNG, IL4, IL6, IL6R, AR, BCL2, LIF, VEGFA, ATF3, IL11, KITLG, ADM, PTGS2, IL6ST, SOX9, INSL3, HIF1A, BIRC5, IGF2, FLT1, FGFR2, FGFR3, MAPK1, KDR, FASLG, MDM2, NODAL, CIB1, ARNT2, ITGB1, CLU, FGFR1, EDNRA, CTNNB1, LEP, AKR1C3, PGF, PTEN, GDF9, IGF1, IL5, INSR, ITGAV, IGF1R, KIT, BMP4, HGF, IL2, NRG1, IL21, CDC7, FGF17, PLAU, FN1, F2R, FGF8, CDC20, SHH, PROK2, ALDH1A2, FGF3, FGF9, SIRPG, MYC, MYCN, MAS1, CSF1, GDNF, PROK1, FOXM1, HOXA3, AREG, CCN2, HDAC4, RPS4X, COX17, BLOC1S2, CDCA7L, DERL2, MCTS1, JAK2, CDC123, NPM1, CD38, GRK5, IL15, ISL1, BAMBI, FXN, EAPP, CACUL1, MTA3, PDCD10, TIPIN, SPHK2, ASH2L, NOX1, NAP1L1, TNS3, CARM1, WDR77, SINHCAF, CNOT8, DNAJA2, CIAO1, GNAI2, IL7, TDGF1, EPCAM, SHC1, RPS9, REG3A, CD47, HDAC2, SLC25A33, CCPG1, FZR1, PDGFB, TGFA, XBP1, PTN, STAT5B, CD81, PURA, PPARD, PTH1R, CALCRL, CCL14, TSLP, NKX3-1, MARCHF7, PLAC8, CLDN5, KRAS, REG1B, EIF5A, PTK2, STX3, HES1, SUZ12, KIF14, CTF1, AQP11, FAM98A, PDGFD, EIF5A2, CHP2, FLT4, MARCKSL1, AKR1C2, RAB25 |
| positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway | biological process | VEGFA, PDGFRB, PDGFRA |
| positive regulation of cell proliferation in bone marrow | biological process | IL6, SHC1, MEF2C, HMGA2, MAP3K3, LEF1, FLT3LG |
| positive regulation of cell proliferation in midbrain | biological process | PITX3 |
| positive regulation of cell proliferation involved in heart morphogenesis | biological process | SOX9, NACA, RBPJ |
| positive regulation of cell proliferation involved in heart valve morphogenesis | biological process | SMAD4 |
| positive regulation of cell proliferation involved in kidney development | biological process | LIN28A |
| positive regulation of cell size | biological process | HIF1A, HSP90AA1, RB1CC1, AMOT, SLC26A5, ATP7A, RET, EDN1 |
| positive regulation of cell volume | biological process | SLC12A2 |
| positive regulation of cell-cell adhesion | biological process | NODAL, ITGA6, SOX2, KIF26B, SIRPG, MEGF10, SIRPB1, CD47, FSTL3, MAGI1, CITED2, MYO10, LEF1, FUT7, FUT3, AFDN |
| positive regulation of cell-cell adhesion mediated by cadherin | biological process | TJP1, DENND6A, FOXA1, WNT3A, SERPINF2, FLOT1, PTPRU, ADAM19, AFDN, FOXA2 |
| positive regulation of cell-cell adhesion mediated by integrin | biological process | CCL5, SKAP1, CD3E, PODXL, PIEZO1 |
| positive regulation of cell-matrix adhesion | biological process | GSK3B, CIB1, CSF1, UTRN, FERMT1, DISC1, EMP2, SKAP1, CD3E, EPB41L5, CDK6, PLEKHA2, PRKCZ, EPHA1, ILK, CCR7, CDH13, JUP, DAG1, CCL28, NINJ1, PTK2B, CCL21, CD36 |
| positive regulation of cell-substrate adhesion | biological process | ITGB1, ITGA5, CCN1, JAK2, HACD1, PTN, ARL2, COL8A1, RELL2, SPOCK2, AGR2, COL26A1, RSU1, ABI3BP, ECM2, EDIL3, RAC1, PRKCE, EMILIN1, VTN, HSD17B12, EGFLAM, SMOC2, FOXF1, VWC2, ITGA3, FBLN2, VIT, NDNF |
| positive regulation of cellular biosynthetic process | biological process | CCL5, AJUBA |
| positive regulation of cellular component biogenesis | biological process | LDB2 |
| positive regulation of cellular component movement | biological process | VEGFA, BCL6, RPS19, STMN1, ETS1, LYN, TGFBR1, PDPN, ACTN4 |
| positive regulation of cellular extravasation | biological process | ICAM1, THY1, PTAFR, ADAM8, PLVAP |
| positive regulation of cellular glucuronidation | biological process | PRKCE |
| positive regulation of cellular metabolic process | biological process | AGPAT1, ACLY, PPARGC1A, FASN, ACACA, ACACB |
| positive regulation of cellular pH reduction | biological process | CA2, AVP, CA7 |
| positive regulation of cellular protein catabolic process | biological process | EZR, FBXL5, PTTG1IP, MSN, RDX, FAF1, UQCC2, DACT1, VGLL4, AMER1, VPS35 |
| positive regulation of cellular protein localization | biological process | IQGAP1, NPTN, PPP1R9B, CYLD, PRKAA2 |
| positive regulation of cellular protein metabolic process | biological process | TGFB1, INHBA, AKT1, NR1H3, CSF1, KLF4, PLA2G10, ADIPOQ, AGTR1, NFKBIA, UHRF1, INS, WNT7A, AGT, PTK2B, NR1H2 |
| positive regulation of cellular respiration | biological process | PRELID1, PPARGC1A |
| positive regulation of cellular response to drug | biological process | KMT2A |
| positive regulation of cellular response to heat | biological process | IER5 |
| positive regulation of cellular response to hypoxia | biological process | KCNK2 |
| positive regulation of cellular response to insulin stimulus | biological process | OPA1, ESRRA, MYO1C |
| positive regulation of cellular response to X-ray | biological process | HMGA2 |
| positive regulation of cellular senescence | biological process | CDKN2A, PAWR, EEF1E1, KRAS, HMGA2, CGAS |
| positive regulation of central B cell tolerance induction | biological process | FOXJ1 |
| positive regulation of centriole elongation | biological process | VPS4B, CEP120, CEP295 |
| positive regulation of centriole replication | biological process | NUP62 |
| positive regulation of centrosome duplication | biological process | ROCK2, CEP120, CEP295 |
| positive regulation of ceramide biosynthetic process | biological process | TNF, TNFRSF1A, PLA2G6, CCN1, SPHK2, RACK1, NSMAF, SMPD3, PRKCD, SMPD2, ENPP7 |
| positive regulation of cerebellar granule cell precursor proliferation | biological process | EGF, SHH, GPR37L1 |
| positive regulation of cGMP biosynthetic process | biological process | APOE |
| positive regulation of cGMP-mediated signaling | biological process | CGAS, NPR1, NPPC, ADORA2B, NPR2, RUNDC3A |
| positive regulation of chaperone-mediated autophagy | biological process | PLK3 |
| positive regulation of chaperone-mediated protein complex assembly | biological process | STUB1 |
| positive regulation of chaperone-mediated protein folding | biological process | SGTA |
| positive regulation of chemokine (C-C motif) ligand 1 production | biological process | TSLP |
| positive regulation of chemokine (C-C motif) ligand 20 production | biological process | TRIM32 |
| positive regulation of chemokine (C-C motif) ligand 5 production | biological process | DDX3X, TICAM2, MCOLN2, MAVS |
| positive regulation of chemokine (C-X-C motif) ligand 1 production | biological process | TIRAP |
| positive regulation of chemokine (C-X-C motif) ligand 2 production | biological process | LPL, POSTN, MBP, LRP1 |
| positive regulation of chemokine (C-X-C motif) ligand 2 production | biological process | TNF, MIF, CD74, TIRAP, HMGB1, MCOLN2 |
| positive regulation of chemokine biosynthetic process | biological process | TNF, IFNG, IL1B, IL4, HMOX1, CD74, EGR1, TLR3, AGER, TICAM1 |
| positive regulation of chemokine production | biological process | TNF, IL6, IL6R, HIF1A, TLR4, TLR2, IL7, TSLP, HAVCR2, RIPK2, FFAR3, EIF2AK2, TLR9, TLR7, TLR3, ADORA2B, LBP, MCOLN2 |
| positive regulation of chemokine secretion | biological process | IL33, LPL, C5, IL1RL1, PYCARD, ALOX15B, CSF1R, IL4R, AIF1 |
| positive regulation of chemokine-mediated signaling pathway | biological process | HIF1A, EDN1 |
| positive regulation of chemotaxis | biological process | TGFB1, FN1, CXCR4, PDGFB, STX3, THBS1, P2RY12, CCL26, CXCR3, CCL19, TREM2, PDGFRB, STX4, RARRES2, CCL21, SUCNR1, AIF1 |
| positive regulation of cholangiocyte proliferation | biological process | MTOR, GPBAR1 |
| positive regulation of cholesterol biosynthetic process | biological process | POR, ABCG1, SREBF1, FGF1 |
| positive regulation of cholesterol efflux | biological process | APOE, PON1, NR1H3, ZDHHC8, CES1, ABCA12, ADIPOQ, ABCG1, NFKBIA, APOA1, GPS2, LRP1, ABCA7, PTCH1, EEPD1, NR1H2, CAV1 |
| positive regulation of cholesterol esterification | biological process | APOE, AGTR1, APOA1, APOC1, APOA5, STARD4, AGT |
| positive regulation of cholesterol homeostasis | biological process | NR1H3 |
| positive regulation of cholesterol import | biological process | LRP1 |
| positive regulation of cholesterol metabolic process | biological process | CES1 |
| positive regulation of cholesterol storage | biological process | APOB, LPL, SREBF2, SCARB1, CD36 |
| positive regulation of cholesterol transport | biological process | NR1H3, LIPG, ABCB4, CETP, NR1H2 |
| positive regulation of choline O-acetyltransferase activity | biological process | SORL1 |
| positive regulation of chondrocyte differentiation | biological process | SOX9, SOX5, GLI3, LOXL2, ZNF219, POR, RELA, SOX6, BMP6, FGF18, RUNX2, HOXA11, ACVRL1, ZBTB16, PKDCC, SMAD3, GDF5 |
| positive regulation of chondrocyte proliferation | biological process | LTF, SIRT6, SIX2, COMP |
| positive regulation of chromatin binding | biological process | EBF2, PYGO2, DTX3L, CTBP2, KDM4D, MED25, HMBOX1, DDX11 |
| positive regulation of chromatin silencing | biological process | SIN3A, MIER1 |
| positive regulation of chromatin silencing at telomere | biological process | SIRT6 |
| positive regulation of chromatin-mediated maintenance of transcription | biological process | CTNNB1 |
| positive regulation of chromosome organization | biological process | LIG4 |
| positive regulation of chromosome segregation | biological process | SMC5, CDC6, NUMA1, RAD18 |
| positive regulation of chromosome separation | biological process | NUMA1 |
| positive regulation of chronic inflammatory response | biological process | IDO1 |
| positive regulation of chronic inflammatory response to antigenic stimulus | biological process | TNF, LTA |
| positive regulation of chronic inflammatory response to non-antigenic stimulus | biological process | ADORA2B |
| positive regulation of chylomicron remnant clearance | biological process | GPIHBP1 |
| positive regulation of cilium assembly | biological process | DZIP1, MNS1, CCP110, ENTR1, ARHGAP35, CCDC88A, CEP120, BBS4, SAXO1, TAPT1, HTT, KCTD17, FUZ, CROCC, MARK4 |
| positive regulation of cilium movement | biological process | TTLL6 |
| positive regulation of circadian rhythm | biological process | BTRC, RORA, ARNTL, THRAP3, RORC, NKX2-1 |
| positive regulation of circadian sleep/wake cycle, non-REM sleep | biological process | GHRL, ALB, GHRHR |
| positive regulation of circadian sleep/wake cycle, sleep | biological process | ADORA2A |
| positive regulation of circadian sleep/wake cycle, wakefulness | biological process | CRH |
| positive regulation of clathrin coat assembly | biological process | HIP1R |
| positive regulation of clathrin-dependent endocytosis | biological process | WASL, DAB2, SCYL2, DGKD |
| positive regulation of CoA-transferase activity | biological process | DBI, CHRNA7 |
| positive regulation of coagulation | biological process | PSEN1 |
| positive regulation of cobalamin metabolic process | biological process | CLYBL |
| positive regulation of cold-induced thermogenesis | biological process | SCD, JAK2, G0S2, CXCR4, OGT, ESRRG, HADH, ADIPOR1, PHOX2B, PRKAB1, KDM6B, OMA1, PLAC8, MFAP2, FABP5, GRB10, ELOVL6, ACSL1, SYK, PPARGC1A, SLN, IL13, ADIPOQ, PEMT, ADRB2, ADRB3, GATM, LPIN1, ADIPOR2, PER2, UCP1, EHMT1, TRPV2, APC, MFN2, CPT2, ACADL, ALMS1, UCP2, FH, DIO2, EPAS1, HDAC3, SIRT6, APPL2, PTH2R, HCRT, ADRB1, TSHR, PDGFC, FGF21, CNOT3, PPARGC1B, CMKLR1, PRDM16, ELOVL3, DBH, THRA, STAT6, ZNF516, ZBTB7B, IL4R, KSR2, CD36, CAV1 |
| positive regulation of collagen binding | biological process | ITGA2 |
| positive regulation of collagen biosynthetic process | biological process | TGFB1, TGFB3, BMP4, F2R, CCN2, SERPINB7, HDAC2, WNT4, SUCO, CBX8, SERPINF2, ITGA2, UCN, LARP6, PRDX5, RGCC, PDGFRB, ENG, F2, ARRB2, IHH |
| positive regulation of collagen catabolic process | biological process | VSIR |
| positive regulation of collagen fibril organization | biological process | COLGALT1 |
| positive regulation of collateral sprouting | biological process | BDNF, BCL11A, RND2, IST1, SEMA4D, EFNA5, LPAR3, CRABP2 |
| positive regulation of collateral sprouting in absence of injury | biological process | WNT3A, WNT3 |
| positive regulation of collateral sprouting of injured axon | biological process | LRP1 |
| positive regulation of complement activation | biological process | C6 |
| positive regulation of connective tissue growth factor production | biological process | ROCK2, IL13 |
| positive regulation of connective tissue replacement | biological process | ROCK2, ROCK1, PPP3CA |
| positive regulation of constitutive secretory pathway | biological process | RAB27A |
| positive regulation of core promoter binding | biological process | KLF4, GTF2B, WNT3A, FOXC1 |
| positive regulation of corticosterone secretion | biological process | TAC1, CRH, ECRG4 |
| positive regulation of corticotropin secretion | biological process | LIF, GHRL, RAB8B, CRH, UCN, ECRG4 |
| positive regulation of corticotropin-releasing hormone secretion | biological process | ECRG4 |
| positive regulation of cortisol biosynthetic process | biological process | WNT4 |
| positive regulation of cortisol secretion | biological process | GHRL, CRH, GALR1, GAL |
| positive regulation of CREB transcription factor activity | biological process | VEGFA, TSSK4, PRKD1, CRTC3, CAMK1D, ADGRF1, ADCY8, OPRD1, LPAR5, RPS6KA5, PRKD2, RPS6KA4, CRTC1, RELN |
| positive regulation of cristae formation | biological process | PINK1, ADCK1, CHCHD10 |
| positive regulation of cyclase activity | biological process | MAPK3, MAPK8, MAPK14 |
| positive regulation of cyclic nucleotide-gated ion channel activity | biological process | CFTR |
| positive regulation of cyclic-nucleotide phosphodiesterase activity | biological process | RACK1, CALM1, CALM2, CALM3 |
| positive regulation of cyclin-dependent protein kinase activity | biological process | STOX1, CDKN1A, TTBK1 |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | SRC, CCNYL1, CCNY, CCNT1, PDGFB, MAPRE3, PSMD10, CKS1B, CCND1, PKD2, CDC6, CCNK, CDK5R1, CDKN1B, SPDYA, RGCC, CDK5R2, MNAT1, PSRC1, CKS2, PROX1, CCND3 |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle | biological process | EGFR, AKT1, PKD1 |
| positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle | biological process | HSPA2 |
| positive regulation of cysteine-type endopeptidase activity | biological process | MEFV, GRIN1, NEK5, AIM2, GRIN2B, PYCARD, BBC3, TTBK1 |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | TNF, FAS, TNFSF10, NODAL, BAD, F2R, MYC, CCN1, ARL6IP5, CCN2, DDX3X, BCL10, PDCD5, BCL2L11, NKX3-1, HTRA2, SYK, WDR35, WNT3A, REST, HMGB1, ACVR1C, PDCD6, NLRP3, BCAP31, FIS1, MAP3K5, NLRP1, DAPK1, CARD8, CARD9, PYCARD, FOXL2, SOX7, NLRP2, NOD1, GRAMD4, BBC3, GPER1 |
| positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway | biological process | LGALS9, HTRA2, PRR7, ST18, TFAP4 |
| positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis | biological process | RPS3, RFPL1 |
| positive regulation of cytochrome-c oxidase activity | biological process | COX17, COA8 |
| positive regulation of cytokine activity | biological process | NRP1 |
| positive regulation of cytokine biosynthetic process | biological process | EREG |
| positive regulation of cytokine production | biological process | SOD1, TNF, LEP, IL21, AGPAT1, CCDC88B, PELI1, AGPAT2, HAVCR2, WNT3A, GATA3, ADRA2A, EREG, FLOT1, IFI16, HHLA2, TNFSF4, SLC11A1, EIF2AK2, HILPDA, NFAM1, TLR3, TLR5, AGT, HTR2B |
| positive regulation of cytokine production involved in immune response | biological process | FFAR3 |
| positive regulation of cytokine production involved in immune response | biological process | KARS1, TNFRSF14, TRIM6 |
| positive regulation of cytokine production involved in inflammatory response | biological process | IL17A, KARS1, MYD88, KPNA6, GBP5, IL17D, NOD2, IL17F, CD6, APPL1, IL17RA, TLR6, TNF, TICAM1 |
| positive regulation of cytokine secretion | biological process | TNF, IL10, CASP1, IL1A, SRC, MIF, SAA1, CLEC6A, SYK, C1QTNF3, PANX1, PTGER4, RGCC, P2RX7, CRTAM, FGR, CLEC9A, CLEC5A, IRF3, INS, HTR2B, IL26 |
| positive regulation of cytokine-mediated signaling pathway | biological process | AXL, GAS6, AGPAT1, CD74, IL7, TSLP, AGPAT2, TRIM44, RIPK2 |
| positive regulation of cytokinesis | biological process | AURKC, CDC42, KIF3B, CIT, SVIL, GIPC1, KIF14, TAS1R2, CXCR5, PKP4, CDC6, PKN2, MRGPRX2, KIF20B, CDC14B, ECT2, CSPP1, OR2A4, PRKCE, DRD3, KIF23, DRD2, CDC25B, SSTR5, AURKB, SPAST, CENPV |
| positive regulation of cytolysis | biological process | LBP |
| positive regulation of cytoplasmic mRNA processing body assembly | biological process | PAN3, CNOT1, PAN2, CNOT6L, CNOT2 |
| positive regulation of cytoplasmic translation | biological process | ZCCHC13, YBX3, DHX36, EEF2, LIN28A |
| positive regulation of cytoskeleton organization | biological process | KATNBL1, SORBS3, P2RX7, PLXNA3 |
| positive regulation of cytosolic calcium ion concentration | biological process | IL1B, ESR1, ADM, GHRL, EDNRA, CD52, IL2, GJA1, F2R, OXTR, CCR5, PROK2, PLA2G6, OXT, PKD1, KISS1, SAA1, TAC1, IAPP, P2RY4, ACKR4, JAK2, CD38, CXCR4, CD55, CCR1, NPTN, BDKRB2, CYSLTR1, CCL1, PTH1R, XCR1, GNB1, CACNA1C, RIC3, SWAP70, GNAT2, CXCR5, PTGER2, SELENOT, PKD2, ACKR3, AGTR1, PTGER1, GIPR, NMU, CAV3, ITPR3, CACNA1A, LRP6, HMGB1, CXCR2, FPR3, ADRA1A, CCR6, TAC4, MCHR1, CHRNA10, PLCE1, EDNRB, PTGDR, JPH2, PTGER3, GLP1R, ADCY8, BCAP31, FIS1, CIB2, ABL1, SLC8A1, C1QTNF1, PTGER4, CX3CR1, GNG3, FKBP1B, HRH4, NPFF, GATA2, ABL2, CCRL2, PIK3CG, CXCR3, DLG4, C3AR1, LPAR1, NMUR2, CALCA, NMB, P2RY1, AVPR1B, LRP1, C5AR2, TRPC5, AVP, CXCR1, FPR2, ADRA1D, CCR7, SPPL3, LPAR3, CXCR6, FFAR1, HCRT, EDN1, PTGIR, S1PR3, CCL28, PDGFRA, ADRA1B, CCR10, GALR1, TRPM4, ADCY5, S1PR4, CALCR, CMKLR1, LPAR2, GPR35, TBXA2R, AGT, CCR3, PTK2B, BDKRB1, ACKR2, CD36, C5AR1, CCR4, TRPV1, GPER1 |
| positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | biological process | EDNRA, F2R, KISS1, LPAR4, F2RL3, LPAR6, S1PR1, AGTR1, GPR4, GPR157, TGM2, C3AR1, LPAR1, CALCA, HTR2C, DRD3, F2RL2, DRD1, GNA15, LPAR3, GPR55, EDN1, DRD2, OPRL1, GPR17, GPR20, GPR35, GPR65, GRM1 |
| positive regulation of cytotoxic T cell differentiation | biological process | TNFSF9, SART1 |
| positive regulation of deacetylase activity | biological process | MAPK8, FNTA, CREB3 |
| positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA | biological process | ZFP36 |
| positive regulation of defense response to bacterium | biological process | HAVCR2, CYBA, UNC13B, GRN |
| positive regulation of defense response to virus by host | biological process | IL4, IL23A, DPF3, SIN3A, ANXA5, ZC3H12A, DTX3L, APOBEC3F, TRAF3IP2, CREB3, IL12RB1, TRIM44, IL23R, PTPN22, IL27, AIM2, ZDHHC11, APOBEC3G, PML, STING1, CGAS, PQBP1, PYCARD, MAVS, TRIM6, ZDHHC1 |
| positive regulation of delayed rectifier potassium channel activity | biological process | NOS1AP, AKAP6 |
| positive regulation of dendrite development | biological process | EZH2, BMP7, COBL, IQGAP1, ALK, PTN, DAB2IP, VLDLR, OPA1, BMP5, CYFIP1, TMEM106B, CRTC1, PACSIN1 |
| positive regulation of dendrite extension | biological process | CXCR4, RIMS2, RIMS1, PRKN, SYT1, CACNG7, CPNE9, NEDD4L, RNF157, ITSN2, SYT17, PLAA, CPNE6, MUL1, CPNE5, UNC13A, SYT2, SYT3, RASAL1 |
| positive regulation of dendrite morphogenesis | biological process | IL1RAPL1, RAB21, ANKRD27, CDKL3, CUX1, CAPRIN1, CUX2, CDKL5, VAMP7, OBSL1, SS18L1, PARP6, EPHA4, ILK, CUL7, FBXW8, SS18L2, CAPRIN2, ANAPC2, FBXO31, PTPRD |
| positive regulation of dendritic cell antigen processing and presentation | biological process | CD74, NOD2, SLC11A1, CCL19, CCR7, NOD1, CCL21 |
| positive regulation of dendritic cell apoptotic process | biological process | LGALS9, RAPGEF2, LYN |
| positive regulation of dendritic cell chemotaxis | biological process | IL12A, GAS6, C1QBP, LGALS9, CCR6, CCR7, CALR |
| positive regulation of dendritic cell cytokine production | biological process | NOD2 |
| positive regulation of dendritic cell dendrite assembly | biological process | CCL19 |
| positive regulation of dendritic cell differentiation | biological process | LGALS9, HMGB1, ZBTB46, AGER |
| positive regulation of dendritic spine development | biological process | APOE, FMR1, MTOR, IL2, NRG1, LLPH, MAPK6, DLG5, NEURL1, ARF1, SHANK2, PSEN1, CDKL5, CPEB3, LPAR1, PPP1R9A, ZMYND8, SHANK1, CAMK1, ITSN1, EURL, Grn |
| positive regulation of dendritic spine maintenance | biological process | APOE, ZMYND8, INS, ZNF804A |
| positive regulation of dendritic spine morphogenesis | biological process | CAMK2B, BAIAP2, EEF2K, KALRN, DHX36, CTTN, CAPRIN1, OPA1, DBNL, CUX2, TIAM1, ACTR2, HCLS1, BHLHB9, PAK3, ITPKA, CAPRIN2, RELN |
| positive regulation of deoxyribonuclease activity | biological process | PCNA |
| positive regulation of dermatome development | biological process | WNT4, WNT3A |
| positive regulation of determination of dorsal identity | biological process | CTNNB1, ACVR1 |
| positive regulation of developmental growth | biological process | C3, LEP, INSR, AGR2, PRKDC |
| positive regulation of developmental pigmentation | biological process | BCL2, BAX |
| positive regulation of digestive system process | biological process | CRH |
| positive regulation of dipeptide transmembrane transport | biological process | CA2, SLC26A6 |
| positive regulation of DNA binding | biological process | EGF, MMP9, ERCC2, PLAUR, IGF1, JAK2, CEBPG, ISL1, HES1, PRKN, EDF1, SKI, SIRT2, PDX1, HMGB1, ITGA2, CALM3, HIPK2, MYOCD, NME1, FOXC1, PYHIN1, MMP8 |
| positive regulation of DNA biosynthetic process | biological process | GSK3B, SRC, HGF, MYC, DDX39B, PDGFB, RGCC, PAK3, PDGFRB, PRKD2, SMOC2, FGF2, FGFR4, ARRB2, PTK2B |
| positive regulation of DNA damage checkpoint | biological process | CCAR2 |
| positive regulation of DNA damage response, signal transduction by p53 class mediator | biological process | ATM, CDKN2A, ATR, EEF1E1, SPRED1, MSX1, PLA2R1, HIC1, ANKRD1 |
| positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | ZNF385A, RPL26, PYHIN1 |
| positive regulation of DNA demethylation | biological process | USP7, USP9X, STPG4, OTUD4 |
| positive regulation of DNA endoreduplication | biological process | E2F7, E2F8 |
| positive regulation of DNA helicase activity | biological process | SSBP1, POT1 |
| positive regulation of DNA ligation | biological process | PARP3, HMGB1, APLF |
| positive regulation of DNA metabolic process | biological process | ANXA3 |
| positive regulation of DNA methylation | biological process | MECP2 |
| positive regulation of DNA N-glycosylase activity | biological process | RPS3 |
| positive regulation of DNA repair | biological process | EGFR, BRCA1, MGMT, PCNA, H2AFX, APEX1, RNF8, NPAS2, CEBPG, UIMC1, RNF168, TMEM161A, UBE2N, RPS3, ERCC6, BABAM1, ERCC8, WRAP53, CBX8, BABAM2, ABRAXAS1, EYA4, SMCHD1, EYA1, TIGAR, APBB1, EYA2, FGF10 |
| positive regulation of DNA replication | biological process | EGFR, IL6, TGFB3, KITLG, CDK1, IGF1, INSR, IGF1R, PCNA, CDC42, MAS1, ATF1, TNFAIP1, KCTD13, ATAD5, MAP2K4, UCN, EREG, CACYBP, RAC1, FAF1, GLI1, STN1, BCAR3, HRAS, GLI2, BRPF3 |
| positive regulation of DNA strand elongation | biological process | POT1 |
| positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity | biological process | HNRNPU, NCAPH, PLSCR1, UHRF1 |
| positive regulation of DNA-dependent DNA replication | biological process | BMP4 |
| positive regulation of DNA-directed DNA polymerase activity | biological process | RFC4, RFC5, RFC3, DSCC1, POLG2, CHTF8, RFC2, CHTF18 |
| positive regulation of DNA-templated transcription, elongation | biological process | HMGN1, SUPT4H1, SUPT16H, DDX39B, THOC1, CCNT1, ELL, ERCC6, ELL3, SUPT5H, ALYREF, CCNK, THOC5, SCAF8 |
| positive regulation of DNA-templated transcription, initiation | biological process | CTNNB1, BCLAF1, SETX, MITF, TWIST1 |
| positive regulation of DNA-templated transcription, termination | biological process | SETX |
| positive regulation of dopamine biosynthetic process | biological process | PARK7, VPS35 |
| positive regulation of dopamine metabolic process | biological process | HPRT1, ABAT |
| positive regulation of dopamine receptor signaling pathway | biological process | CAV2, DRD3, LRRK2, VPS35 |
| positive regulation of dopamine secretion | biological process | GDNF, SYT1, PINK1, CHRNB2, CXCL12 |
| positive regulation of dopamine uptake involved in synaptic transmission | biological process | RAB3B, DRD2, DRD4 |
| positive regulation of dopaminergic neuron differentiation | biological process | FGF20 |
| positive regulation of double-strand break repair | biological process | MGMT, FOXM1, SLF2, WRAP53, TIMELESS, NUDT16, SPIRE1, SLF1, DDX11, SPIRE2, SPIDR, FMN2 |
| positive regulation of double-strand break repair via homologous recombination | biological process | FUS, ARID2, ERCC6, WRAP53, TIMELESS, ACTR2, MMS19, WAS, MRNIP |
| positive regulation of double-strand break repair via nonhomologous end joining | biological process | DTX3L, KMT5B, SHLD2, KDM4D, WRAP53, PARP3, PRKDC, SMCHD1, FH, SHLD1, MAD2L2, RIF1, KMT5C |
| positive regulation of dUTP diphosphatase activity | biological process | RGN |
| positive regulation of early endosome to late endosome transport | biological process | EZR, RAB21, PTPN23, DAB2, MSN, RDX |
| positive regulation of early endosome to recycling endosome transport | biological process | SORL1 |
| positive regulation of eating behavior | biological process | MTOR, GHSR |
| positive regulation of embryonic development | biological process | AMOT, LHX1, B4GALT5, RBM19, DIEXF, NIBAN2, NR2C2, FOXA2 |
| positive regulation of enamel mineralization | biological process | ODAPH |
| positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation | biological process | TWIST1 |
| positive regulation of endocytic recycling | biological process | ACTN2, SORL1, EHD2, EIPR1 |
| positive regulation of endocytosis | biological process | ITGB1, MIB1, EEF2K, MAPK8IP1, SNCA, DAB2, ARF1, CD151, FLOT1, AP2B1, PPP3CA, NEDD4L, CBLL1, CCL19, TFR2, LRP1, CALY, DLL1, GPC3, MAPK8IP2, CLIP3 |
| positive regulation of endodeoxyribonuclease activity | biological process | AKT1, RPS3, PRKCD, DDX11 |
| positive regulation of endodermal cell differentiation | biological process | MACROH2A1 |
| positive regulation of endopeptidase activity | biological process | PRELID1, PSMD14, PSENEN, PSME1, ADRM1, SERPINB3, SFRP2, AKIRIN2, VSIR |
| positive regulation of endoplasmic reticulum calcium ion concentration | biological process | ATP2A2, ATP2A1 |
| positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation | biological process | PPP1R15A |
| positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | DDIT3, RNF183, BCL2L11, NCK1, PTPN2, NCK2, SERINC3, BOK |
| positive regulation of endoplasmic reticulum tubular network organization | biological process | ATL3, RAB3GAP2, RAB3GAP1, LNPK |
| positive regulation of endoplasmic reticulum unfolded protein response | biological process | BAX, BAK1, PIK3R1, XBP1, ERN1 |
| positive regulation of endoribonuclease activity | biological process | HSPA1A |
| positive regulation of endosome organization | biological process | SYNJ1 |
| positive regulation of endosome to plasma membrane protein transport | biological process | ZDHHC2, AKAP5 |
| positive regulation of endothelial cell apoptotic process | biological process | FASLG, AKR1C3, BMP4, XBP1, ANO6, THBS1, PDCD4, RGCC, COL18A1, CD160, FOXO3, CD248, CD40, CCL2, GPER1 |
| positive regulation of endothelial cell chemotaxis | biological process | HSPB1, PRKD1, LGMN, PRKD2, SMOC2, FGF2, P2RX4, SEMA5A |
| positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway | biological process | VEGFA, KDR, HSPB1, PRKD1, PRKD2 |
| positive regulation of endothelial cell chemotaxis to fibroblast growth factor | biological process | FGFR1, FGF18, FGF2 |
| positive regulation of endothelial cell differentiation | biological process | CTNNB1, BMP4, ETV2, BTG1, VEZF1, NOTCH1, TMEM100, BMP6, ACVRL1, GDF2 |
| positive regulation of endothelial cell migration | biological process | VEGFA, KDR, BMP4, BMPR2, RIN2, CCBE1, ZC3H12A, EMC10, TDGF1, ADGRA2, ANXA3, PRKD1, ROCK2, RRAS, FLT4, SCARB1, BCAR1, FOXP1, THBS1, GATA3, TEK, ETS1, ANGPT4, GPLD1, ANGPT1, ITGB1BP1, NRP2, PDCD6, ITGB3, ABL1, GPI, FOXC2, BCAS3, SASH1, TSTA3, GRN, PRKD2, SMOC2, EDN1, NRP1, PROX1, CALR, WNT7A, AGT, FGF1, PTK2B |
| positive regulation of endothelial cell proliferation | biological process | VEGFA, HIF1A, AKT1, KDR, F3, MTOR, PGF, BMP4, BMPR2, ECM1, EMC10, PDGFB, AGGF1, TNFSF12, PRKD1, FLT4, CCL11, MYDGF, CYBA, TEK, VASH2, CAV2, NRP2, PDCD6, ITGB3, EGR3, PPP1R16B, CCL26, TGFBR1, VEGFC, LRG1, NRARP, SCG2, BMP6, CDH13, PRKD2, EGFL7, BMP2, VEGFB, PLXNB3, FGF2, THBS4, ACVRL1, NRP1, DYSF, ANG, PROX1, NR4A1, RPTOR, GDF2, STAT5A, CXCL12, NF1, CCR3, SEMA5A, HTR2B |
| positive regulation of endothelial cell-matrix adhesion via fibronectin | biological process | RIN2, RRAS, CEACAM6, TSTA3 |
| positive regulation of endothelial tube morphogenesis | biological process | ITGAX |
| positive regulation of endothelin production | biological process | AGER |
| positive regulation of energy homeostasis | biological process | GHRL |
| positive regulation of engulfment of apoptotic cell | biological process | TREM2, ABCA7 |
| positive regulation of eosinophil chemotaxis | biological process | IL4, DAPK2 |
| positive regulation of eosinophil degranulation | biological process | STX4 |
| positive regulation of eosinophil differentiation | biological process | IL5, TRIB1 |
| positive regulation of eosinophil migration | biological process | ADAM8 |
| positive regulation of ephrin receptor signaling pathway | biological process | RBPJ |
| positive regulation of epidermal cell differentiation | biological process | BMP4, SULT2B1, IL20, PTCH2, SFN, KDF1, SFRP4, PTCH1 |
| positive regulation of epidermal growth factor receptor signaling pathway | biological process | ESR1, MMP9, ESR2, AKT1, FASLG, PLAUR, SOS1, ARAP1, NUP62, SHKBP1, CCDC88A, AFAP1L2, AGR2, CNOT9, CBL, PDE6G, DOK1, PTK6, HIP1R, DGKD, AGT, HAP1, GPER1 |
| positive regulation of epidermal growth factor-activated receptor activity | biological process | EGF, AREG, FBXW7, TGFA, NEURL1, ADRA2A, EREG, NCF1, HBEGF, BTC |
| positive regulation of epidermis development | biological process | PPARD, TMEM79, ELAPOR2, KRT2 |
| positive regulation of epinephrine secretion | biological process | CARTPT |
| positive regulation of epithelial cell apoptotic process | biological process | JAK2, TIA1, SORT1, ARRB2 |
| positive regulation of epithelial cell differentiation | biological process | SOX9, CTNNB1, FOXN1, WNT10B |
| positive regulation of epithelial cell migration | biological process | IFNG, SOX9, INSL3, HIF1A, SRC, BMPR2, TAC1, RAB11A, RTN4, ENPP2, RAB25, GLIPR2, ITGA2, CCR6, CAPN7, DOCK5, EPB41L5, TGFB2, DOCK1, RREB1, PRKCE, HDAC6, CLASP2, TGFBR2, CTSH, ITGA3, CLASP1, PLCG2, VIL1, FGF10 |
| positive regulation of epithelial cell proliferation | biological process | EGFR, TGFB1, ESR1, IL6, VEGFA, SOX9, ERBB2, FGFR2, NODAL, BAD, IGF1, BMP4, CCL5, MMP12, FGF9, MYC, LAMC1, TGFA, BMPR1A, CCND1, NOTCH1, NOD2, GLUL, STOX1, SMO, BMP5, TWIST1, DLX6, FOXP2, VEGFC, ATP7A, WDR48, NME2, YAP1, BMP6, LAMB1, GRN, DLX5, ESRP2, C5AR2, FGF7, MAP2K5, EYA1, HRAS, NME1, NR4A3, HTRA1, IHH, SCN5A, FGF1, FOXE3, OSR2, FGF10, C5AR1 |
| positive regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | FGFR2, CDC42, SRSF6, FOXP2, FGF7 |
| positive regulation of epithelial cell proliferation involved in prostate gland development | biological process | CTNNB1, SHH |
| positive regulation of epithelial cell proliferation involved in wound healing | biological process | MMP12, ODAM, FZD7, B4GALT1, JAML, CLDN1, WNT7A, FGF10 |
| positive regulation of epithelial to mesenchymal transition | biological process | TGFB1, TGFB3, EZH2, CTNNB1, ISL1, BAMBI, OLFM1, SMAD4, HDAC2, LOXL2, DAB2, NOTCH1, MDK, TGFB1I1, GCNT2, GLIPR2, TGFB2, TIAM1, SDCBP, TWIST1, SERPINB3, BCL9L, TGFBR1, SMAD2, RGCC, LEF1, PDPN, TGFBR2, ZNF703, AXIN2, BMP2, CRB2, WWTR1, FOXC1, SMAD3, ALX1 |
| positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological process | ACVR1, TGFB2, TGFBR1, TGFBR2, ENG |
| positive regulation of ER to Golgi vesicle-mediated transport | biological process | STX18, ARF1, TBC1D20, SORL1 |
| positive regulation of ER-associated ubiquitin-dependent protein catabolic process | biological process | NFE2L2, SGTA, XBP1, HERPUD1, BCAP31, CAV1 |
| positive regulation of ERAD pathway | biological process | BAG6, USP13, TMEM259, ATXN3, RNFT1, RNF185 |
| positive regulation of ERBB signaling pathway | biological process | RBPJ |
| positive regulation of ERBB3 signaling pathway | biological process | RTN4 |
| positive regulation of ERK1 and ERK2 cascade | biological process | EGFR, TNF, IL1B, ESR1, IL6, ICAM1, VEGFA, CD44, FSHR, ESR2, FGFR2, FGFR3, MAPK3, KDR, GAS6, NODAL, CIB1, TLR4, SEMA7A, C3, EDNRA, PTEN, BMP4, SRC, CCL5, MIF, F2R, FGF8, RAP1A, PTPN11, NTRK1, PLA2G2A, CX3CL1, CCL16, IAPP, CCN2, CCL20, ROR1, AKAP12, KARS1, CD74, CCR1, GPR183, CCL8, NPTN, LGALS9, GNAI2, SHC1, FBXW7, DNAJC27, RAPGEF2, PDGFB, CCL1, CCL14, CCL3, PDGFD, NDRG4, BRAF, FLT4, CCL11, NRXN1, GPNMB, RASGRP1, FGG, CHI3L1, HAVCR2, HCRTR1, HMGCR, NELFE, NOTCH1, FGF23, NOD2, SERPINF2, TEK, NTRK2, SLC30A10, PHB2, MARCO, CCL22, ACKR3, TIRAP, GCNT2, GLIPR2, PTPN22, MAP2K7, FGB, PTPRC, HMGB1, ADRA1A, CHRNA7, ARHGAP8, RAPGEF1, CFLAR, PDGFA, ANGPT1, MAP3K12, FGF20, CCL26, RIPK2, ABL1, ALKAL2, MTURN, PRKCZ, DSTYK, CAVIN3, S100A7, CCL18, CCL23, CCL19, TREM2, SPRY2, RAMP3, FGF18, MT3, HTR2C, P2RY1, MAP2K1, LRP1, ALKAL1, C5AR2, CD4, PDGFRB, CCL3L1, FPR2, SSTR4, CCR7, PLA2G5, ATP6AP1, PRKD2, GAREM1, PYCARD, GPR55, MFHAS1, PDE8A, FGF19, HRAS, FGA, BMP2, VEGFB, CCL7, PDGFC, FGF21, FGF2, PDGFRA, SLAMF1, BMPER, NRP1, NQO2, F |
| positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling | biological process | TNFRSF11A |
| positive regulation of ERK5 cascade | biological process | ALKAL2, ALKAL1 |
| positive regulation of erythrocyte differentiation | biological process | INHBA, HIF1A, MAPK14, ACVR1B, MAPK11, STAT5B, ISG15, ETS1, PRKDC, SMAP1, BRD1, GATA2, ACVR2A, PRMT1, ID2, ANKRD54, NCKAP1L, FAM210B, FOXO3, INPP5D, HSPA1A, HSPA1B, GATA1 |
| positive regulation of erythrocyte enucleation | biological process | TRIM58 |
| positive regulation of establishment of endothelial barrier | biological process | PROC, CLDN5, F11R, S1PR2, CDH5, ADD1 |
| positive regulation of establishment of protein localization | biological process | CEP120, CEP295, PTP4A3, CORO2B |
| positive regulation of establishment of protein localization to plasma membrane | biological process | IFNG, AKT1, CIB1, ITGB1, EZR |
| positive regulation of establishment of protein localization to telomere | biological process | CCT5, CCT4, DKC1, CCT7, CCT2, TCP1, CCT6A, CCT3, WRAP53, CCT8 |
| positive regulation of establishment of T cell polarity | biological process | env, DOCK8 |
| positive regulation of estradiol secretion | biological process | SPP1 |
| positive regulation of excitatory postsynaptic potential | biological process | GSK3B, PTEN, RIMS2, BAIAP2, GRIN1, RIMS1, DVL1, NRXN1, NLGN2, SHANK2, CHRNA7, STX1B, CUX2, PRKCZ, DLG4, SSH1, CACNB3, SHANK1, WNT7A, PTK2B, RGS4, RELN, NETO1 |
| positive regulation of excitatory synapse assembly | biological process | WNT7A |
| positive regulation of execution phase of apoptosis | biological process | TP53, ZC3H12A, TP53BP2, DLC1, SIRT2, PTGIS, BOK, CXCR3 |
| positive regulation of exit from mitosis | biological process | TGFB1, BIRC5, NEUROG1, PHB2, UBE2C, CDCA5 |
| positive regulation of exocytosis | biological process | CFTR, PLA2G6, RAB9A, RAB2B, RAB27A, SNCA, EXPH5, SYTL4, FGG, RAB5A, STXBP5, RAB27B, CADPS, FGB, CADPS2, NCS1, CLASP2, ATP6AP1, UNC13D, FGA, VSNL1, CLASP1 |
| positive regulation of exoribonuclease activity | biological process | TCEA1 |
| positive regulation of exosomal secretion | biological process | IFNG, CHMP2A, TSG101, VPS4B, HGS, STAM, ATP13A2, SDC4, SMPD3, RAB7A, SDCBP, SNF8, PDCD6IP, SDC1 |
| positive regulation of extracellular exosome assembly | biological process | SDC4, SDCBP, PDCD6IP, SDC1 |
| positive regulation of extracellular matrix assembly | biological process | TGFB1, SOX9, RGCC, EMILIN1, SMAD3 |
| positive regulation of extracellular matrix constituent secretion | biological process | RGCC, AGT |
| positive regulation of extracellular matrix disassembly | biological process | PDPN, CLASP2, MELTF, CARMIL2, FSCN1, CLASP1 |
| positive regulation of extracellular matrix organization | biological process | CFLAR |
| positive regulation of extrinsic apoptotic signaling pathway | biological process | FAS, TNFSF10, PDIA3, G0S2, BCL10, DEDD2, TNFSF12, ITM2C, FADD, PTPRC, BID, CYLD, RBCK1, PML, BCL2L14, HYAL2, TNFRSF12A, PYCARD, LTBR, TRAF2, AGT, WWOX, CAV1, GPER1 |
| positive regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | INHBA, FAS, BAX, PPP2R1B, CTNNA1, HTRA2, SRPX, RET, PPP2R1A, NF1, WWOX |
| positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | SKIL, STK3, STK4, THBS1, TRPS1, PEA15, FAF1, MAL |
| positive regulation of eye pigmentation | biological process | HPS4 |
| positive regulation of fast-twitch skeletal muscle fiber contraction | biological process | ATP2A1 |
| positive regulation of fat cell apoptotic process | biological process | LEP |
| positive regulation of fat cell differentiation | biological process | AKT1, SULT1E1, IGF1, PPARG, STK3, ZC3H12A, CARM1, ZNF385A, CCDC3, LPL, STK4, ASXL2, LMO3, AAMDC, XBP1, PPARD, ADIRF, FRZB, WIF1, TPH1, SYAP1, SAV1, CREBL2, CDS1, TMEM64, ADIG, ZFP36, ZFP36L1, KLF5, MEDAG, LRP5, HTR2C, ID2, SFRP2, BMP2, WDFY2, GDF3, ZBTB16, TRPM4, RARRES2, CMKLR1, SH3PXD2B, ZBTB7C, WNT5B |
| positive regulation of fat cell proliferation | biological process | PID1 |
| positive regulation of fatty acid beta-oxidation | biological process | CPT1A, ABCD2, IRS2, IRS1, TWIST1, AKT2, ABCD1, PPARA |
| positive regulation of fatty acid biosynthetic process | biological process | NR1H3, RGN, MID1IP1, ELOVL5, APOA1, APOA5, NR1H2 |
| positive regulation of fatty acid metabolic process | biological process | PPARD, ADIPOQ, GHSR, PPARA |
| positive regulation of fatty acid oxidation | biological process | PPARG, MLYCD, PPARGC1A, NR4A3, PPARA |
| positive regulation of Fc receptor mediated stimulatory signaling pathway | biological process | CD226, LYN |
| positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | PTPRC, RAPGEF1, APPL2 |
| positive regulation of feeding behavior | biological process | CFAP20, RXFP4, NR4A3, SGIP1 |
| positive regulation of female receptivity | biological process | NCOA2, OXT, NCOA1, THRA |
| positive regulation of ferrous iron binding | biological process | B2M, HFE |
| positive regulation of ferrous iron import into cell | biological process | B2M, HFE |
| positive regulation of fertilization | biological process | CFAP69, LHFPL2, CCDC87 |
| positive regulation of fever generation | biological process | TNF, IL1B, PTGS2, CCL5, CNR1, PTGER3 |
| positive regulation of fever generation by positive regulation of prostaglandin secretion | biological process | TNFRSF11A |
| positive regulation of fibrinolysis | biological process | F12, PLG |
| positive regulation of fibroblast apoptotic process | biological process | TP63, BTG1, BCL2L11, STK17A, STK17B, BID, PRDM11 |
| positive regulation of fibroblast growth factor production | biological process | PTGS2, ROCK2, AIF1 |
| positive regulation of fibroblast growth factor receptor signaling pathway | biological process | CTNNB1, FGFBP3, NPTN, NRXN1, DSTYK, PRKD2, SMOC2, FGFBP1 |
| positive regulation of fibroblast migration | biological process | TGFB1, AKT1, ARHGEF7, PTK2, BAG4, THBS1, SLC8A1, PRKCE, PAK3, DMTN |
| positive regulation of fibroblast proliferation | biological process | EGFR, TGFB1, ESR1, LIG4, CCNB1, E2F1, GAS6, IGF1, MIF, FN1, ANXA2, MYC, CCNA2, CD74, RNASEH2B, WAPL, NDUFS4, PDGFB, PDGFD, ZMIZ1, S100A6, FBLN1, CDC6, EREG, PDGFA, BMI1, CDK6, PRKDC, FOSL2, PML, PLA2G1B, CDKN1A, SIRT6, AQP1, PDGFRB, BTC, PDGFC, NGFR, PDGFRA, AGT, FGF10 |
| positive regulation of fibronectin-dependent thymocyte migration | biological process | ADAM8 |
| positive regulation of filopodium assembly | biological process | TGFB3, FMR1, WASL, ARAP1, RALA, DPYSL3, NEURL1, GPM6A, FNBP1L, DNM3, DOCK11, ESPN, RHOQ, MIEN1, TENM2, TGFBR1, BCAS3, PALM, SRF, CCR7, ZMYND8, NRP1, AGRN, FSCN1, CCL21, RIPOR2 |
| positive regulation of flagellated sperm motility | biological process | PGAM4, CFAP69, TAC4, TACR2 |
| positive regulation of flagellated sperm motility involved in capacitation | biological process | DEFB1, CCR6 |
| positive regulation of focal adhesion assembly | biological process | VEGFA, KDR, PTPRJ, IQGAP1, TSC1, WNT4, SDC4, MAP4K4, TEK, ROCK1, EPB41L5, ITGB1BP1, RAC1, ABL1, HRG, THY1, S100A10, NRP1, COL16A1, SMAD3, FMN1, MYOC |
| positive regulation of focal adhesion disassembly | biological process | MAP4K4, IQSEC1, DUSP3, ARF6 |
| positive regulation of follicle-stimulating hormone secretion | biological process | INHBA, LEP, INHA, SMAD4, FOXL2 |
| positive regulation of forebrain neuron differentiation | biological process | PROX1 |
| positive regulation of free ubiquitin chain polymerization | biological process | PINK1 |
| positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity | biological process | IFNG |
| positive regulation of fructose 1,6-bisphosphate metabolic process | biological process | IFNG |
| positive regulation of G-protein coupled receptor protein signaling pathway | biological process | C3, PTGDR2, PDE6G, GAS2L2, KLK5, DRD2, KLK6, SLC39A14, GPER1 |
| positive regulation of G0 to G1 transition | biological process | CCN2, SOX15, RHNO1 |
| positive regulation of G1 to G0 transition | biological process | RAB11FIP4 |
| positive regulation of G1/S transition of mitotic cell cycle | biological process | CYP1A1, APEX1, AIF1, TFDP1, DDX3X, PLRG1, LSM11, ANXA1, CCND1, CDC45, ANKRD17, MEPCE, UBE2E2, RDX, KMT2E, RGCC, RPTOR, CCND3, FGF10 |
| positive regulation of G2/M transition of mitotic cell cycle | biological process | APP, CDC7, BRD4, SIN3A, RAB11A, MTA3, RAD51C, PHOX2B, VPS4B, DTL, SMARCD3, CCND1, RCC2, STOX1, PBX1, MECP2, RAD51B, DBF4B, WNT10B, CDC25B |
| positive regulation of G2/MI transition of meiotic cell cycle | biological process | CDC25B |
| positive regulation of gamma-aminobutyric acid secretion | biological process | TRH, P2RX7, NTSR1 |
| positive regulation of gamma-delta T cell activation | biological process | NOD2 |
| positive regulation of gamma-delta T cell differentiation | biological process | STAT5B, SYK, PTPRC, SOX4, LEF1, NCKAP1L |
| positive regulation of gap junction assembly | biological process | ACE2, AGT, CAV1 |
| positive regulation of gastric acid secretion | biological process | OPRL1, TRPV1 |
| positive regulation of gastric mucosal blood circulation | biological process | PTGER2 |
| positive regulation of gastro-intestinal system smooth muscle contraction | biological process | PTAFR |
| positive regulation of gastrulation | biological process | RACK1, LHX1, TENM4, FOXA2 |
| positive regulation of gene expression | biological process | TGFB1, TNF, IFNG, IL1B, AMH, TP53, IL6, INHBA, AR, VDR, LIF, VEGFA, ATF3, BRCA1, SOX9, IL18, HIF1A, NR1I2, APOB, CDK1, DNMT1, HNF1B, MDM2, E2F1, GAS6, NFE2L2, CTCFL, DNMT3B, TLR4, TLR2, IL1A, CRP, VIM, CTNNB1, STAT3, MTOR, HFE, PARK7, KIT, BMP4, SRC, CCL5, CD46, MAPK8, NGF, FN1, HSPA1A, HSPA1B, EZR, GJA1, EPHX2, FGF8, CDC42, SHH, CYP26B1, DROSHA, ALDH1A2, PIP, FGF9, IL33, MYCN, CSF1, MAPK14, ETV2, TADA3, IAPP, CCN2, RPL5, RPS7, GJC2, OVOL2, BCL11A, KDM5B, DDX3X, TRIM24, KLF4, UBR5, TLE1, DNAJA4, PAWR, OLFM1, PDCD10, RIMS2, SLC22A2, NKX2-2, CD74, RPL11, ANK3, ZC3H12A, GATA5, DHX36, AGO4, CALCOCO1, LGALS9, ATMIN, IL7, HOXD3, ACVR1B, RAB27A, HNRNPD, MAPK11, PRKAB1, PDCD5, LAMTOR5, ZMPSTE24, PDGFB, IFNGR1, STAR, PPARD, RIMS1, TP53INP1, NKX3-1, MYD88, LAMP3, CLDN5, NOS1AP, KRAS, CCL3, RPS3, EPHB2, IQGAP3, FAM98A, FEV, RBM4B, WNT10A, STAP1, NCOA3, PRKN, ROCK2, TFRC, BRAF, EGR1, WARS1, CD34, HCFC1, NRXN1, IL1F10, PPARGC1A, HGS, RAMP2, LDLR, RLN2, IL13, SERPINB9, MAZ, SRPK2, IL34, KDM4C, AGO3, ATP13A2, MAFG, NOTCH1, |
| positive regulation of gene expression, epigenetic | biological process | ACTB, HIST1H4A, POLR1F, POLR1B, POLR1H, POLR2F, SPHK2, SF3B1, SMARCA5, DEK, BAZ1B, POLR1C, ERCC6, DDX21, POLR1E, POLR1A, TAF1C, TAF1B, TAF1A, POLR2L, POLR2E, EP300, MACROH2A1, POLR2K, TAF1D, KAT2A, MYO1C, POLR2H, KAT2B, MYBBP1A, WBP2 |
| positive regulation of gene silencing by miRNA | biological process | FMR1, STAT3, PUM2, PUM1, FXR1, AJUBA, WTIP, ZFP36, TRIM71, LIMD1 |
| positive regulation of germinal center formation | biological process | TNFSF13B, ADA, TNFRSF13C |
| positive regulation of glial cell apoptotic process | biological process | CDK5 |
| positive regulation of glial cell differentiation | biological process | IL1B, SPINT1, NOTCH1 |
| positive regulation of glial cell migration | biological process | CRKL |
| positive regulation of glial cell proliferation | biological process | MTOR, ETV5, PRKCH, LYN, LTA, TNF |
| positive regulation of glial cell-derived neurotrophic factor secretion | biological process | CD34, SORL1, DRD2 |
| positive regulation of gliogenesis | biological process | SOX10 |
| positive regulation of glomerular filtration | biological process | GAS6, GJA1, PDGFB |
| positive regulation of glomerular mesangial cell proliferation | biological process | SERPINB7, PDGFB, PDGFD, CFLAR |
| positive regulation of glomerular metanephric mesangial cell proliferation | biological process | EGR1 |
| positive regulation of glomerular visceral epithelial cell apoptotic process | biological process | PPARGC1A, PLA2R1, PLA2G1B |
| positive regulation of glucagon secretion | biological process | AIMP1 |
| positive regulation of glucocorticoid receptor signaling pathway | biological process | NCOA2, LMO3, PPP5C |
| positive regulation of glucokinase activity | biological process | BAD, PFKFB2, RANBP2 |
| positive regulation of gluconeogenesis | biological process | FOXO1, PTPN2, WDR5, DGAT2, PPARGC1A, ARPP19, GPT, PPP4R3B, KAT2A, KAT2B, PPARA, DDB1 |
| positive regulation of glucose catabolic process to lactate via pyruvate | biological process | ACTN3 |
| positive regulation of glucose import | biological process | AKT1, NFE2L2, IGF1, INSR, RAP1A, MAPK14, SORBS1, PIK3R1, C2CD5, SLC1A2, ADIPOQ, ARPP19, RNASEL, ADIPOR2, OSBPL8, IRS2, IRS1, RHOQ, CREBL2, CLTCL1, POU4F2, ITLN1, FGF19, FGF21, APPL1, GPC3, CAPN10, INS, AKT2 |
| positive regulation of glucose import in response to insulin stimulus | biological process | PTPN11 |
| positive regulation of glucose mediated signaling pathway | biological process | SMARCA4, SMARCB1 |
| positive regulation of glucose metabolic process | biological process | AKT1, SRC, RGN, IRS2, IRS1, GPLD1, SLC25A12, AKT2 |
| positive regulation of glucose transport | biological process | C3, C2CD5, BRAF, NR4A3, CLIP3 |
| positive regulation of glucosylceramide catabolic process | biological process | PRKCD |
| positive regulation of glutamate metabolic process | biological process | NR1H4 |
| positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization | biological process | RAB3GAP1 |
| positive regulation of glutamate receptor signaling pathway | biological process | UNC13A, NECAB2 |
| positive regulation of glutamate secretion | biological process | P2RX7, AVP, CCK, NTSR1, ADORA2A |
| positive regulation of glutamine transport | biological process | SLC38A3 |
| positive regulation of glutathione biosynthetic process | biological process | NFE2L2 |
| positive regulation of glutathione peroxidase activity | biological process | SNCA |
| positive regulation of glycogen (starch) synthase activity | biological process | IGF2, ADIPOQ, EPM2AIP1 |
| positive regulation of glycogen biosynthetic process | biological process | IGF2, AKT1, IGF1, INSR, SORBS1, IRS2, IRS1, DYRK2, EPM2AIP1, INS, AKT2, GCK, ESRRB |
| positive regulation of glycogen catabolic process | biological process | PHKG2 |
| positive regulation of glycolytic process | biological process | HIF1A, IGF1, INSR, GAPDHS, ZBTB20, SLC4A4, PFKFB2, ENTPD5, PSEN1, PRKAA2, P2RX7, PFKFB4, INS, ESRRB |
| positive regulation of glycoprotein biosynthetic process | biological process | IGF1, INSR, CCL19, CCL21 |
| positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation | biological process | CCR7 |
| positive regulation of glycoprotein metabolic process | biological process | RAB1A, RAB1B |
| positive regulation of Golgi lumen acidification | biological process | UBE3A |
| positive regulation of Golgi to plasma membrane protein transport | biological process | CNST, RACK1, ACSL3, ANXA13, CLN3 |
| positive regulation of granulocyte chemotaxis | biological process | S100A7 |
| positive regulation of granulocyte colony-stimulating factor production | biological process | ISL1, TSLP, CD34 |
| positive regulation of granulocyte differentiation | biological process | HAX1, RUNX1, TESC, LEF1, HCLS1, EVI2B |
| positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | biological process | SYK, CD80 |
| positive regulation of granulocyte macrophage colony-stimulating factor production | biological process | IL1B, IL18, IL23A, PAEP, ISL1, RASGRP1, IL17D, IL23R, TLR9 |
| positive regulation of granulosa cell proliferation | biological process | MTOR |
| positive regulation of granzyme B production | biological process | PTPN22, CD244 |
| positive regulation of growth | biological process | WFS1, GHSR, TFCP2L1, CSHL1, GH2, ZPR1, CSH1, CSH2 |
| positive regulation of growth factor dependent skeletal muscle satellite cell proliferation | biological process | STAT3, JAK2 |
| positive regulation of growth hormone receptor signaling pathway | biological process | GHRL, JAK2, MBD5 |
| positive regulation of growth hormone secretion | biological process | GHRL, KISS1, SERP1, SELENOT, GHRHR, DRD2, ITSN1 |
| positive regulation of growth rate | biological process | RFTN1 |
| positive regulation of GTPase activity | biological process | EGFR, EGF, ICAM1, KITLG, GNAS, ERBB2, FGFR2, FGFR3, GSK3B, EZH2, ITGB1, GNAO1, FGFR1, A2M, IL2RA, IL5, KIT, CCL5, ITGA6, ARHGDIA, GFRA1, IL2, NRG1, FGF17, NCAM1, FGF8, RAP1A, SOS1, NTRK1, FGF3, FGF9, RANGAP1, SBF1, GDNF, AGFG1, CX3CL1, CCL16, ASAP2, SIPA1L3, RASA1, CCL20, ACAP2, RAB11FIP2, RIN2, ELMOD3, EVI5, RABEP1, SEC23B, RGPD4, USP6NL, ARFGEF1, KALRN, CHN1, IQGAP1, CCL8, RGN, RALGAPA1, ARAP1, ALS2, ARHGAP32, GDI2, PIN1, ARHGEF7, ACAP1, RASGRP3, ZC3H15, RTN4R, RGS17, ERRFI1, RAPGEF2, ARHGEF11, SRGAP3, CCL1, RACK1, RALBP1, CCL14, DEPDC1, DAB2IP, TBC1D19, NPRL2, ANKRD27, AGAP4, VAV3, GNB5, RGS16, CCL3, CHML, OCRL, RASA2, PREX2, DLC1, ARHGAP9, SIPA1L2, RABGAP1, RGS20, BCR, CCL11, ABR, BNIP2, ARHGEF6, GARNL3, DENND1A, RAPGEF6, ARHGAP35, ARHGAP33, RASGRP1, WNT4, ARHGEF5, RINL, ADAP2, RASAL2, DEPDC5, S1PR1, PICALM, STXBP5, ARAP2, SEMA4D, TBC1D20, RIC8B, TBC1D30, MAP4K4, RASGRP2, ARFGAP1, GIT1, CCL22, RGS11, RIN1, ARHGAP17, IQSEC1, ARAP3, PKP4, ARHGEF12, LARS1, ODAM, CDC42EP2, CAV2, ARHGAP8, ARHGAP5, RAPGEF1, DOC |
| positive regulation of guanylate cyclase activity | biological process | NOS3, NOS2, RCVRN, GUCA1A, GUCA2B, ADORA2B, GUCA1C, GUCA2A |
| positive regulation of hair cycle | biological process | TERT |
| positive regulation of hair follicle cell proliferation | biological process | CDC42, FGF10 |
| positive regulation of hair follicle development | biological process | TNF, FST, HPSE, FOXN1, NUMA1, KRT17, TRADD |
| positive regulation of heart contraction | biological process | ATP1A2, TGFB2, ATP1A1, ADRB1, HRC, NKX2-5 |
| positive regulation of heart growth | biological process | WT1, BASP1, PROX1, ACACB |
| positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway | biological process | DKK1, WNT11, MESP1 |
| positive regulation of heart rate | biological process | ADM, TACR3, ATP2A2, ATP5PF, RYR2, NMU, ADRA1A, ADA, GCH1, HEY2, EDN1, HRC, TRPM4, EDN3, RGS4, SCN3B |
| positive regulation of heart rate by epinephrine | biological process | TPM1 |
| positive regulation of heart rate by epinephrine-norepinephrine | biological process | ADRA1A, ADRA1D, ADRB1, ADRA1B |
| positive regulation of heat generation | biological process | SLC27A1, NMU, ABAT |
| positive regulation of helicase activity | biological process | MSH2, SSBP1, POT1, MSH6, CHTOP |
| positive regulation of hematopoietic progenitor cell differentiation | biological process | DHX36, FOXC1 |
| positive regulation of hematopoietic stem cell differentiation | biological process | FOXC1 |
| positive regulation of hematopoietic stem cell migration | biological process | PTPRC |
| positive regulation of hematopoietic stem cell proliferation | biological process | KITLG, PDCD2, N4BP2L2, ATXN1L, THPO |
| positive regulation of hemoglobin biosynthetic process | biological process | KLF4, LDB1, PRMT1 |
| positive regulation of heparan sulfate proteoglycan biosynthetic process | biological process | CTNNB1, TCF7L2, PXYLP1 |
| positive regulation of hepatic stellate cell activation | biological process | LEP, RPS6KA1, PDGFRB |
| positive regulation of hepatic stellate cell migration | biological process | AKAP12 |
| positive regulation of hepatocyte differentiation | biological process | BMP4, MESP1 |
| positive regulation of hepatocyte growth factor receptor signaling pathway | biological process | ESM1 |
| positive regulation of hepatocyte proliferation | biological process | RTN4, XBP1, PTN, WNT3A, HPN, MDK, CFLAR, FGF1 |
| positive regulation of heterochromatin assembly | biological process | TPR |
| positive regulation of heterotypic cell-cell adhesion | biological process | TNF, IL1B, CD44, BMP7, FGG, GCNT2, FGB, CEACAM6, SKAP1, FLOT1, FGA, THY1, LCK, AGER |
| positive regulation of hexokinase activity | biological process | TIGAR |
| positive regulation of hh target transcription factor activity | biological process | SHH, STK36, SMO |
| positive regulation of high voltage-gated calcium channel activity | biological process | CACNA2D1, NIPSNAP2, CACNB3, FGF14, CACNB2 |
| positive regulation of high-density lipoprotein particle assembly | biological process | NR1H2 |
| positive regulation of high-density lipoprotein particle clearance | biological process | LIPG, GPLD1 |
| positive regulation of hindgut contraction | biological process | OXT |
| positive regulation of hippo signaling | biological process | DLG5, FRMD1, SOX11 |
| positive regulation of hippocampal neuron apoptotic process | biological process | ITGAM, TYROBP |
| positive regulation of histamine secretion by mast cell | biological process | SNX4, VAMP8, PLA2G3, VAMP7 |
| positive regulation of histone acetylation | biological process | TGFB1, IL1B, BRCA1, MAPK3, ISL1, RUVBL2, PPARGC1A, GLYR1, TADA2A, NAP1L2, RPS6KA5, KAT2A, RPS6KA4, PAXIP1 |
| positive regulation of histone deacetylase activity | biological process | VEGFA, PRKD1, PINK1, C6orf89, PRKD2, LRRK2 |
| positive regulation of histone deacetylation | biological process | TGFB1, TP53, BCL6, AKAP8, JDP2, ING2, NIPBL, PML, CTBP1, SREBF1, AKAP8L, ZBTB7B |
| positive regulation of histone deubiquitination | biological process | SART3 |
| positive regulation of histone H2B ubiquitination | biological process | CDK9, RNF20, CTR9, RNF40 |
| positive regulation of histone H3-K14 acetylation | biological process | PIWIL2, GATA3, NAP1L2, WBP2 |
| positive regulation of histone H3-K27 acetylation | biological process | LIF |
| positive regulation of histone H3-K27 methylation | biological process | EED, OGT, PHF1, MTF2 |
| positive regulation of histone H3-K36 methylation | biological process | PAXIP1 |
| positive regulation of histone H3-K36 trimethylation | biological process | NSD3 |
| positive regulation of histone H3-K4 methylation | biological process | BRCA1, DNMT1, DNMT3B, CTNNB1, WDR61, SMAD4, AUTS2, WDR5, RTF1, NELFE, CTR9, KMT2A, SNW1, PAXIP1 |
| positive regulation of histone H3-K4 trimethylation | biological process | KMT2E |
| positive regulation of histone H3-K79 methylation | biological process | WDR61, CTR9 |
| positive regulation of histone H3-K9 acetylation | biological process | BRCA1, PIWIL2, SPHK2, SMAD4, GATA3, SMARCB1, NAP1L2 |
| positive regulation of histone H3-K9 dimethylation | biological process | Dmrtc2, PRDM12 |
| positive regulation of histone H3-K9 methylation | biological process | BRCA1, JARID2, RIF1, PRDM12, H1-5 |
| positive regulation of histone H3-K9 trimethylation | biological process | Dmrtc2, MECP2 |
| positive regulation of histone H4 acetylation | biological process | MUC1, SMARCB1 |
| positive regulation of histone H4-K16 acetylation | biological process | BRCA1, AUTS2 |
| positive regulation of histone H4-K20 methylation | biological process | BRCA1 |
| positive regulation of histone methylation | biological process | RNF20, PAX7, XBP1, PAF1, CHTOP, TET1, PAXBP1 |
| positive regulation of histone modification | biological process | UBE2N |
| positive regulation of histone phosphorylation | biological process | IL1B, FMR1, CCNB1, MAPK3, ATM, CDK9, RPS6KA5, RPS6KA4 |
| positive regulation of homocysteine metabolic process | biological process | COMT |
| positive regulation of homophilic cell adhesion | biological process | PTPN23 |
| positive regulation of homotypic cell-cell adhesion | biological process | CCL5, ANK3, JAK1 |
| positive regulation of hormone biosynthetic process | biological process | HIF1A, EGR1 |
| positive regulation of hormone secretion | biological process | KISS1R, PTPN11, NMU, GHRHR, SOX11, NMB, P2RY1, EDN1, EDN3 |
| positive regulation of humoral immune response | biological process | FCGR2B, CCR7, ZP3 |
| positive regulation of humoral immune response mediated by circulating immunoglobulin | biological process | TNF, PTPRC, FCER2, LTA |
| positive regulation of hyaluranon cable assembly | biological process | BMP7, HAS3 |
| positive regulation of hyaluronan biosynthetic process | biological process | EGF, PDGFB, HAS2 |
| positive regulation of hydrogen peroxide biosynthetic process | biological process | ZNF205, MT-CO2, DUOXA2, DUOXA1 |
| positive regulation of hydrogen peroxide catabolic process | biological process | SNCA, NNT |
| positive regulation of hydrogen peroxide-mediated programmed cell death | biological process | PAWR, ENDOG, HDAC6, FOXO3 |
| positive regulation of hydrogen sulfide biosynthetic process | biological process | SP1 |
| positive regulation of hydrolase activity | biological process | PSAP, APOA1, GM2A |
| positive regulation of hypersensitivity | biological process | CCR7 |
| positive regulation of hypoxia-inducible factor-1alpha signaling pathway | biological process | RWDD3 |
| positive regulation of I-kappaB kinase/NF-kappaB signaling | biological process | TNF, IL1B, TNFRSF1A, CASP1, TNFSF10, HMOX1, FASLG, S100A12, CASP8, TLR4, IL1A, CTNNB1, LTF, GJA1, F2R, BRD4, ECM1, MALT1, ROR1, CLEC6A, DDX1, TMEM9B, TERF2IP, TBK1, PLK2, TRIM13, CD74, MIER1, DHX36, GOLT1B, LGALS9, APOL3, BCL10, BST2, TRIM25, PELI1, TMEM101, MAP3K7, LAMTOR5, IRAK1, UBE2N, WLS, TRIM58, SLC20A1, ALPK1, MYD88, S100A4, NUP62, PRKD1, ZDHHC17, DDX21, TRAF3IP2, PRKN, TFRC, ZC3HAV1, IL1F10, UBD, ADIPOQ, CXXC5, LURAP1L, AJUBA, TNFRSF10B, ATP2C1, TFG, NOD2, TNFRSF19, UBE2I, RELA, TRIM32, FADD, IKBKE, TRIM8, PELI2, TSPAN6, TIRAP, EEF1D, PINK1, VAPA, CFLAR, PRKCB, REL, BIRC2, MAP3K3, IKBKG, ANKRD17, UBE2V1, CANT1, SHARPIN, TAB2, GPR89A, TRIM38, ECT2, RIPK2, ABL1, TICAM2, TIFA, LITAF, NDFIP1, RBCK1, NDFIP2, TRAF6, CTH, AKAP13, PPM1A, CARD16, ZDHHC13, TAB3, TMEM106A, S100B, TGM2, PPP5C, PRKCE, LPAR1, CASP10, CCL19, TRIM62, GPRC5B, IL36G, IKBKB, CCDC22, TRADD, TMED4, TRIM52, MAP3K14, CARD9, TLR9, MID2, TRAF5, CD4, CCR7, INAVA, TNIP2, EDA, TRIM21, UNC5CL, MUL1, EDAR, TLR3, PIM2, RHOC, IRF3, SLC44A2, EDA2R, N |
| positive regulation of I-kappaB phosphorylation | biological process | CX3CR1, DDRGK1, TRAF2, TNF |
| positive regulation of icosanoid secretion | biological process | CYP4A11, CYP4F2 |
| positive regulation of immature T cell proliferation | biological process | RIPK2 |
| positive regulation of immature T cell proliferation in thymus | biological process | IL1B, SHH |
| positive regulation of immune complex clearance by monocytes and macrophages | biological process | PLA2G5 |
| positive regulation of immune response | biological process | ELANE, IL15, IFNL1, CTSG, TGFB2, PLA2G1B, FCER1G, IFNL3, IFNL4 |
| positive regulation of immune response to tumor cell | biological process | HRG |
| positive regulation of immune system process | biological process | PRKDC, AQP3 |
| positive regulation of immunoglobulin biosynthetic process | biological process | MZB1 |
| positive regulation of immunoglobulin mediated immune response | biological process | CD226, TNFSF4 |
| positive regulation of immunoglobulin production | biological process | IL4, XBP1, IL13, TLR9, IL4R, CLCF1 |
| positive regulation of immunoglobulin production in mucosal tissue | biological process | C17orf99 |
| positive regulation of immunoglobulin secretion | biological process | IL6, HLA-E, IL5, IL2, IL33, XBP1, TNFRSF4, VAMP3, GPI, TNFSF4, STX4, RBP4 |
| positive regulation of immunological synapse formation | biological process | CCR7 |
| positive regulation of inclusion body assembly | biological process | PSMC5, CDC34 |
| positive regulation of inflammatory response | biological process | TNFRSF1A, IL18, IL23A, SERPINE1, S100A12, TLR4, TLR2, EDNRA, CCL5, IL2, IL21, CLOCK, IL33, S100A9, PLA2G2A, CX3CL1, JAK2, IL15, LPL, CD47, MGST2, LILRA5, CCL1, SNCA, STAT5B, TSLP, CCL3, LDLR, MDK, PDCD4, AGTR1, NAPEPLD, TLR10, NFKBIZ, ZBP1, ETS1, ITGA2, NFKBIA, GPR4, DEFB114, CDK19, PTGER4, S100A8, IL1RL1, PLA2G7, OSM, TGM2, TNFSF4, HYAL2, IL16, TNIP1, GPRC5B, NLRP12, TRADD, TLR9, TLR7, TLR3, PDE2A, ADAM8, MAPK13, IL17RA, CCN4, AGT, SUCNR1, TNF, ZP3 |
| positive regulation of inflammatory response to antigenic stimulus | biological process | CD81, CD28 |
| positive regulation of inflammatory response to wounding | biological process | MDK, GRN |
| positive regulation of inhibitory G protein-coupled receptor phosphorylation | biological process | APLNR |
| positive regulation of inhibitory postsynaptic potential | biological process | RIMS2, RIMS1, NLGN2, UNC13B, ABAT, NTSR1, IGSF9B |
| positive regulation of inhibitory synapse assembly | biological process | SEMA4D |
| positive regulation of innate immune response | biological process | MMP2, CCL5, POLR3F, HMGB3, GBP5, HAVCR2, SH2D1B, HMGB1, EREG, RIOK3, PLSCR1, POLR3C, CARD9, FPR2, POLR3D, ADAM8, COCH, POLR3B |
| positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | biological process | PKD2, HTT, P2RY6, HAP1 |
| positive regulation of inositol phosphate biosynthetic process | biological process | MAS1, SNCA, PTH1R, CD244, AVPR1B, PTAFR, ADCYAP1R1, NTSR1 |
| positive regulation of inositol trisphosphate biosynthetic process | biological process | LHCGR, HRH1, P2RY1, P2RY6, GPER1 |
| positive regulation of inositol-polyphosphate 5-phosphatase activity | biological process | PLEK |
| positive regulation of insulin receptor signaling pathway | biological process | IGF2, LEP, SRC, SORBS1, GNAI2, ADIPOR1, GKAP1, OPA1, OSBPL8, SNX5, IRS1, NR1H4, PRKCZ, SORL1, INS, SERPINA12, ZBTB7B, AGT |
| positive regulation of insulin secretion | biological process | GHRL, TRH, BAD, GJA1, MYRIP, TCF7L2, GLUD1, NNAT, AACS, JAK2, CD38, ISL1, SERP1, PPARD, NLGN2, IRS2, PFKFB2, GIPR, PDX1, SLC30A8, GLUL, PSMD9, ACSL4, ABAT, SOX4, TM7SF3, PRKCE, FFAR1, UCN3, RBP4, CAPN10, GCK, GPR68, RPH3AL, DOC2B, BLK, GPER1 |
| positive regulation of insulin secretion involved in cellular response to glucose stimulus | biological process | HLA-DRB1, HIF1A, CFTR, BAD, PLA2G6, KIF5B, SRI, MPC2, NADK, PHPT1, PPP3CB, CRH, PDX1, OXCT1, GPLD1, NR1H4, ADCY8, RAC1, LRP1, RFX6, C2CD2L, STX4, VSNL1, TRPM4, GPR27, CLTRN, ANO1, BAIAP3, GPR68 |
| positive regulation of insulin-like growth factor receptor signaling pathway | biological process | GH1, IGF1, PHIP, GHSR, GHRHR, IGFBP4, CDH3, IGFBP5, MYORG |
| positive regulation of integrin activation | biological process | SRC, PLEK, SKAP1, PIEZO1, RASIP1, RAP1B |
| positive regulation of integrin activation by cell surface receptor linked signal transduction | biological process | P2RY12, CDH17 |
| positive regulation of integrin biosynthetic process | biological process | AR, NOX1, TGFB2 |
| positive regulation of integrin-mediated signaling pathway | biological process | EMP2, CD63, LOXL3, DMTN, LIMS2 |
| positive regulation of interferon-alpha biosynthetic process | biological process | TLR9, TLR7, TLR3 |
| positive regulation of interferon-alpha production | biological process | TLR4, HSPD1, TBK1, DDX3X, IFIH1, ZC3HAV1, IRF5, RIPK2, IRF7, IRF3, MAVS |
| positive regulation of interferon-alpha secretion | biological process | IFIH1, DHX36, PTPN22, HMGB1, MAVS |
| positive regulation of interferon-beta biosynthetic process | biological process | TLR4, TBK1, TLR9, TLR7, TLR3, TICAM1 |
| positive regulation of interferon-beta production | biological process | TLR4, TLR2, TBK1, DDX3X, IFIH1, POLR3F, ZC3HAV1, DHX58, ZBTB20, RNF135, POLR3A, IRF5, FLOT1, RIOK3, RIPK2, POLR3C, IRF1, IRF7, TLR9, POLR3D, TLR3, IRF3, MAVS, POLR3B |
| positive regulation of interferon-beta secretion | biological process | IFIH1, PTPN22, MAVS |
| positive regulation of interferon-gamma biosynthetic process | biological process | IL21, CEBPG, IL27, TLR9, TNFRSF13C, TLR7, TLR3, EBI3, ZFPM1 |
| positive regulation of interferon-gamma production | biological process | TNF, IL1B, HLA-DPB1, IL12A, IL18, IL23A, TLR4, IL2, HSPD1, ISL1, IL1R1, BCL3, CD226, IL12RB1, HAVCR2, FADD, IFNL1, SCRIB, IL23R, CD3E, PDE4B, RIPK2, HLA-DPA1, PDE4D, TNFSF4, SLC11A1, SLAMF6, CRTAM, IRF8, FZD5, PYCARD, HRAS, IL12RB2, IL27RA, LTA, TXK, ZP3 |
| positive regulation of interferon-gamma secretion | biological process | LGALS9, RASGRP1, PTPN22, ABL1, CD2, CD244, CD160 |
| positive regulation of interferon-gamma-mediated signaling pathway | biological process | IRGM, TXK |
| positive regulation of interleukin-1 alpha production | biological process | ISL1, CALCA |
| positive regulation of interleukin-1 alpha secretion | biological process | CASP1, PANX1, IL16, P2RX7 |
| positive regulation of interleukin-1 beta biosynthetic process | biological process | JAK2, EGR1, TYROBP, AZU1, TNF, AGER |
| positive regulation of interleukin-1 beta production | biological process | HSPB1, JAK2, ISL1, MNDA, NOD2, AIM2, IFI16, P2RX7, INAVA, PYCARD, NOD1, SMAD3, PYHIN1 |
| positive regulation of interleukin-1 beta secretion | biological process | IFNG, CASP1, LGALS9, LPL, LILRA5, CCL3, ORM1, PANX1, NOD2, NLRP7, HMGB1, PYDC1, NLRP3, STMP1, AIM2, RIPK2, NLRP1, ORM2, LILRA2, P2RX7, CCL19, CARD8, NLRP12, FZD5, PYCARD, TRIM16, NLRP2, GSDMD |
| positive regulation of interleukin-1 production | biological process | TLR4, HDAC2, HAVCR2 |
| positive regulation of interleukin-1 secretion | biological process | SAA1, PANX3, ORM1, PANX1, HMGB1, ORM2, PANX2 |
| positive regulation of interleukin-1-mediated signaling pathway | biological process | IL1R1 |
| positive regulation of interleukin-10 biosynthetic process | biological process | BCL3, SYK |
| positive regulation of interleukin-10 production | biological process | IL4, IL23A, TLR4, HGF, CD46, HSPD1, CD83, IL20RB, TSLP, CD34, NOD2, PIBF1, HMGB1, TUSC2, TNFSF4, TREM2, TLR9, FCER1G, INAVA, CD28 |
| positive regulation of interleukin-10 secretion | biological process | LGALS9, LILRA5, IL13, CD274, PRKCZ, PYCARD, LGALS9B |
| positive regulation of interleukin-12 biosynthetic process | biological process | IFNG, TLR4, SYK, LTB, RELA, TRAF6, IRF1 |
| positive regulation of interleukin-12 production | biological process | IFNG, IL23A, TLR4, TLR2, HLA-G, HSPD1, ISL1, IDO1, TIRAP, IL23R, HMGB1, IRF5, RIPK2, TNFSF4, CCL19, IRF8, TLR9, CCR7, TLR3, CD40, CD36, AGER |
| positive regulation of interleukin-12 secretion | biological process | MAPK14, LGALS9, MAPK11, MDK, IL16, CCL19 |
| positive regulation of interleukin-13 production | biological process | IL4, HLA-E, IL33, TSLP, IL1RAP, GATA3, NLRP3, TNFSF4, RARA |
| positive regulation of interleukin-13 secretion | biological process | PAEP, LGALS9, GATA3, PRKCZ, IL17RA |
| positive regulation of interleukin-15 production | biological process | TIRAP |
| positive regulation of interleukin-17 production | biological process | TGFB1, IL18, IL23A, IL2, IL21, IL15, MYD88, NOD2, PRKCQ, IL23R, SLAMF6, LY9 |
| positive regulation of interleukin-17 secretion | biological process | CCL1, OSM |
| positive regulation of interleukin-17-mediated signaling pathway | biological process | TRIM32 |
| positive regulation of interleukin-18 production | biological process | TLR2, NLRP9, TLR9 |
| positive regulation of interleukin-18-mediated signaling pathway | biological process | TICAM2 |
| positive regulation of interleukin-2 biosynthetic process | biological process | IL1B, IL1A, STAT5B, CD86, PRKCQ, PTPRC, CD3E, CD4, CD28, CARD11, CD80 |
| positive regulation of interleukin-2 production | biological process | MALT1, CD83, MAP3K7, RPS3, ANXA1, RUNX1, PDE4B, RIPK2, TRAF6, PDE4D, PRKD2, TRAF2, CARD11 |
| positive regulation of interleukin-2 secretion | biological process | SPTBN1, ABL1, VTCN1 |
| positive regulation of interleukin-23 production | biological process | IFNG, IL17A, MYD88, IL17RA |
| positive regulation of interleukin-3 biosynthetic process | biological process | SYK |
| positive regulation of interleukin-33 biosynthetic process | biological process | TNF |
| positive regulation of interleukin-4 biosynthetic process | biological process | CD86 |
| positive regulation of interleukin-4 production | biological process | HLA-E, IL33, LGALS9, IL20RB, SYK, HAVCR2, EPX, GATA3, PRKCQ, CD3E, NLRP3, PRKCZ, TNFSF4, FCER1G, CD28, RARA, ZP3 |
| positive regulation of interleukin-4-dependent isotype switching to IgE isotypes | biological process | TNFSF4 |
| positive regulation of interleukin-4-mediated signaling pathway | biological process | PARP14, CD300LF |
| positive regulation of interleukin-5 production | biological process | IL33, TSLP, IL1RAP, GATA3, NLRP3, PDE4D, IL1RL1, RARA |
| positive regulation of interleukin-5 secretion | biological process | TSLP, GATA3, CRLF2, PRKCZ, IL17RA |
| positive regulation of interleukin-6 biosynthetic process | biological process | IFNG, IL1B, CD74, SYK, TIRAP, TLR1, EREG, TYROBP, TRAF6, PTAFR, TLR6, TNF, AGER |
| positive regulation of interleukin-6 production | biological process | TNF, IL1B, IL6, IL6R, TLR4, TLR2, HSPD1, IL33, ISL1, TSLP, MYD88, IL17D, NOD2, ZBTB20, TBC1D23, CYBA, HMGB1, UCN, RIPK2, ARHGEF2, POU2F2, TNFSF4, P2RX7, CARD9, TLR9, FCER1G, INAVA, TLR7, PYCARD, TLR3, AKIRIN2, ADORA2B, SPON2, IL1RL2, NOD1, MAPK13, LBP, MMP8, POU2AF1, CD36, TICAM1 |
| positive regulation of interleukin-6 secretion | biological process | IL1B, PAEP, IL17A, F2R, IFIH1, LGALS9, LPL, LILRA5, XBP1, DHX58, IL1RAP, HMGB1, MBP, TWIST1, LILRA2, HYAL2, IL16, PYCARD, IL17F, LGALS9B, MAVS, AIF1 |
| positive regulation of interleukin-6-mediated signaling pathway | biological process | GFI1 |
| positive regulation of interleukin-8 biosynthetic process | biological process | TNF, TLR4, ELANE, CD74, BCL10, LAMTOR5, SYK, RELA, TLR9, TLR7 |
| positive regulation of interleukin-8 production | biological process | TNF, IL1B, SERPINE1, TLR4, TLR2, PARK7, HSPA1A, HSPA1B, DDIT3, MYD88, ADIPOQ, IL17D, AFAP1L2, NOD2, FADD, TIRAP, HMGB1, CALCA, TLR9, PRKD2, TLR7, TLR3, GDF2, TLR5, LBP, MAVS |
| positive regulation of interleukin-8 secretion | biological process | F2R, LGALS9, CD58, CAMP, TLR1, FCN1, CD2, HYAL2, CD244, PYCARD, TNF |
| positive regulation of intermediate filament depolymerization | biological process | NES |
| positive regulation of intestinal cholesterol absorption | biological process | LPCAT3, ENPP7 |
| positive regulation of intestinal epithelial structure maintenance | biological process | SLC22A5 |
| positive regulation of intracellular cholesterol transport | biological process | SCP2 |
| positive regulation of intracellular estrogen receptor signaling pathway | biological process | FOXA1, KMT2D, SKP2, PAGR1, YAP1, WBP2 |
| positive regulation of intracellular mRNA localization | biological process | DHX36, ZFP36, ZFP36L1 |
| positive regulation of intracellular protein transport | biological process | CDC42, KIF5B, PCM1, PDCD10, RAB29, ZFAND1, CEP131, PRR5L, RUFY3, KIF20B, ICE1, OAZ1, CEP290, OAZ2, TPR, ASPH, BCAS3, PCNT, PLK3, CHRM1, B3GAT3, RIPOR1 |
| positive regulation of intracellular signal transduction | biological process | SRC, SLC9A1, TEK, PRKD2, FGF1, LRRK1 |
| positive regulation of intracellular transport | biological process | MLC1, CREBRF, NUMA1, CAPN10 |
| positive regulation of intracellular transport of viral material | biological process | FMR1 |
| positive regulation of intrinsic apoptotic signaling pathway | biological process | TP53, BCL2, BAX, CLU, BAD, DNM1L, 38231, S100A9, SIAH1, DDIT3, BCLAF1, GSDME, BCL2L11, PRKRA, RACK1, NKX3-1, SLC9A3R1, NUPR1, BID, BCAP31, BECN1, FIS1, TAF6, BOK, S100A8, FLCN, PLAGL2, BMF, BCL2L1, RIPK3, LCK, PLEKHF1, BBC3, CAV1 |
| positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | RPS7, RPL11, MSX1, UBB |
| positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage | biological process | SKIL, RPS3, NACC2, RAD9A, FBH1, PIAS4 |
| positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | RPL26 |
| positive regulation of invadopodium disassembly | biological process | NAV3 |
| positive regulation of inward rectifier potassium channel activity | biological process | ALG10B, TREM2 |
| positive regulation of ion transmembrane transport | biological process | SLC9A3R1, ANO6, P2RX7, KCNC1 |
| positive regulation of ion transmembrane transporter activity | biological process | WNK3, WNK4, HTR3A, WNK1, WNK2 |
| positive regulation of ion transport | biological process | LEP, IL13, P2RY12, TACR2, P2RY1, CHRM1 |
| positive regulation of IP-10 production | biological process | MAVS |
| positive regulation of IRE1-mediated unfolded protein response | biological process | BAX, BAK1, BCL2L11, DAB2IP, AGR2, PTPN1, TMEM33 |
| positive regulation of isotype switching | biological process | HMCES, KMT5B, SHLD2, TFRC, EXOSC3, SHLD1, MAD2L2, TP53BP1, RIF1, KMT5C, EXOSC6, PAXIP1 |
| positive regulation of isotype switching to IgA isotypes | biological process | TGFB1, NSD2, TNFSF13 |
| positive regulation of isotype switching to IgE isotypes | biological process | IL4, STAT6, CLCF1 |
| positive regulation of isotype switching to IgG isotypes | biological process | IFNG, IL4, IL2, ATAD5, PTPRC, TBX21, CD28, CD40, PAXIP1 |
| positive regulation of JAK-STAT cascade | biological process | IL6, IL10, PRL, LEP, GH1, IL5, KIT, CCL5, F2R, CYP1B1, AKR1B1, ADIPOR1, HES1, IL10RA, NOTCH1, IFNL1, CRLF3, CSHL1, GH2, GHR, CSH1, IL10RB, F2, CSH2, TNF, IL26 |
| positive regulation of JNK cascade | biological process | TNF, IL1B, TLR4, IL1A, CDC42, PJA2, GADD45B, CCN2, STK3, RB1CC1, NOX1, MAP4K2, DUSP22, DUSP19, DUSP15, MAPK8IP1, DAB2IP, FLT4, WNT7B, TRAF3, RASGRP1, TAOK2, FCGR2B, SH3RF1, NOD2, TNFRSF19, SERPINF2, TIRAP, SH3RF3, TAOK3, AXIN1, FZD7, HMGB1, GADD45A, ANKRD6, NCF1, RASSF2, HIPK2, SDCBP, TPD52L1, ZNF622, RIPK2, MTURN, MAP3K5, TRAF6, TAOK1, SH3RF2, TRAF4, MAP3K10, CCL19, CARD9, TLR9, TRAF5, CCR7, PYCARD, MFHAS1, FGF19, HRAS, UNC5CL, EDAR, TLR3, SLAMF1, TRAF1, EDA2R, NOD1, LTBR, TRAF2, MINK1, WNT7A, PTK2B, CCL21, MMP8, AGER, WNT16 |
| positive regulation of JUN kinase activity | biological process | TNF, IL1B, ZEB2, MAP3K4, DUSP19, FZD8, FZD4, MAP3K7, DAB2IP, RPS3, ARHGEF5, DKK1, TAOK3, TIAM1, VANGL2, DVL2, MAP3K5, TRAF6, EPHA4, SASH1, MAP3K10, TLR9, FZD5, FGD2, DVL3, TNFRSF11A, EDN1, ROR2, TRAF2, PTK2B, TLR6, AGER |
| positive regulation of keratinocyte apoptotic process | biological process | SFRP4, PIAS4 |
| positive regulation of keratinocyte differentiation | biological process | VDR, OVOL2, PRKCH, MACROH2A2, NCOA3, NOTCH1, IL20, CYP27B1, MACROH2A1, NUMA1, NME2, TRIM16, FOXC1, ALOX15B |
| positive regulation of keratinocyte migration | biological process | MMP9, MAP4K4, HAS2, IQSEC1, ADAM9, EPB41L4B, HBEGF, ARF6, FGF7, FGF10 |
| positive regulation of keratinocyte proliferation | biological process | TP63, AREG, STXBP4, REG3A, TGM1, MDK, REG3G, HAS2, FGF7, CDH3, FGF10 |
| positive regulation of kidney development | biological process | SOX9, EDNRA, BMP4 |
| positive regulation of kidney smooth muscle cell differentiation | biological process | SHH |
| positive regulation of killing of cells of other organism | biological process | IFNG, NOS2, SYK, FCER2 |
| positive regulation of kinase activity | biological process | NBN, RYK, ROR1, CD74, BCL10, ALK, LTK, EPHB2, TIE1, FLT4, GCN1, AJUBA, ROS1, TEK, NTRK2, MOB1B, EPHB1, MRE11, EPHA6, ZNF622, DSTYK, EPHA4, VAC14, PIFO, RAD50, EPHA1, ERBB3, CD4, RET, PDGFRB, EPHA2, EPHA7, MST1R, PDGFRA, EPHA3, EPHA8, FGFR4, CSF1R, INSRR, EPHB3, EPHB4, ROR2, EPHA10, MERTK, ITSN1, DRD4, EPHB6, TYRO3 |
| positive regulation of L-arginine import across plasma membrane | biological process | AGT |
| positive regulation of L-dopa biosynthetic process | biological process | PARK7 |
| positive regulation of L-dopa decarboxylase activity | biological process | PARK7 |
| positive regulation of L-glutamate import across plasma membrane | biological process | ARL6IP1, PSEN1 |
| positive regulation of L-lysine import across plasma membrane | biological process | AGT |
| positive regulation of lactation | biological process | XBP1 |
| positive regulation of lamellipodium assembly | biological process | HSP90AA1, MTOR, HDAC4, ACTR3, NCKAP1, AUTS2, FRMD7, AKIRIN1, PLCE1, RAC1, WASF2, RAC2, ATP7A, ACTR2, TWF2, MSTN, AVIL, CARMIL2, FSCN1 |
| positive regulation of lamellipodium morphogenesis | biological process | SRC, CORO1B, ENPP2, ARHGEF7, CORO1C, RREB1, VIL1 |
| positive regulation of lamellipodium organization | biological process | CARMIL1, CARMIL2 |
| positive regulation of large conductance calcium-activated potassium channel activity | biological process | GAL |
| positive regulation of late endosome to lysosome transport | biological process | SNAPIN, ARF1 |
| positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore | biological process | AURKB |
| positive regulation of lateral motor column neuron migration | biological process | RELN |
| positive regulation of lens epithelial cell proliferation | biological process | SOX11, FOXE3 |
| positive regulation of lens fiber cell differentiation | biological process | ZEB2, FGF2 |
| positive regulation of leukocyte activation | biological process | TEX101 |
| positive regulation of leukocyte adhesion to arterial endothelial cell | biological process | TNF, ALOX5 |
| positive regulation of leukocyte adhesion to vascular endothelial cell | biological process | IRAK1, MDK, RELA, ETS1, TRAF6, NFAT5, ITGB2, FUT7, TNF |
| positive regulation of leukocyte apoptotic process | biological process | NR4A3 |
| positive regulation of leukocyte cell-cell adhesion | biological process | ITGA4, MDK, SKAP1, LCK, PTAFR |
| positive regulation of leukocyte chemotaxis | biological process | IL6, IL6R, PTN, F7, MDK, CXCR2, EDN3, CXCL10 |
| positive regulation of leukocyte mediated cytotoxicity | biological process | NOS2 |
| positive regulation of leukocyte migration | biological process | VEGFA, KITLG, ITGA4, CCL8, ITGA2B, MADCAM1, SELP, ITGA2, MIA3, TNFRSF18, BDKRB1, ZP3 |
| positive regulation of leukocyte proliferation | biological process | BST2, IL5RA |
| positive regulation of leukocyte tethering or rolling | biological process | ITGA4, SELP, FUT7, PTAFR |
| positive regulation of leukotriene production involved in inflammatory response | biological process | SERPINE1 |
| positive regulation of ligase activity | biological process | MID1IP1, XRCC4, RIPK3, NHEJ1 |
| positive regulation of lipase activity | biological process | RHOC |
| positive regulation of lipid biosynthetic process | biological process | APOE, AKT1, MTOR, SORBS1, CCDC3, SIRT4, ZBTB20, APOA1, CREBL2, APOA5, ABHD6, INS |
| positive regulation of lipid catabolic process | biological process | IL1B, ABHD5, ANGPTL3, PRKCE, APOA5, SCT |
| positive regulation of lipid kinase activity | biological process | EEF1A2, F2 |
| positive regulation of lipid metabolic process | biological process | DISP3 |
| positive regulation of lipid storage | biological process | APOB, C3, PLA2G10, ZC3H12A, LPL, ASXL2, IKBKE, HILPDA, ACACB, NR1H2 |
| positive regulation of lipid transport | biological process | LRP1 |
| positive regulation of lipid transport across blood brain barrier | biological process | APOE |
| positive regulation of lipophagy | biological process | ADRB2, SPTLC1, HTT, SPTLC2, SESN2 |
| positive regulation of lipopolysaccharide-mediated signaling pathway | biological process | MIF, LY96, LY86, TRAF6, SASH1, BMP6 |
| positive regulation of lipoprotein lipase activity | biological process | NR1H3, ABHD5, GPIHBP1, APOA1, APOA5, LMF1, APOH, NR1H2 |
| positive regulation of lipoprotein metabolic process | biological process | PEMT |
| positive regulation of locomotion | biological process | BVES |
| positive regulation of locomotion involved in locomotory behavior | biological process | VPS35 |
| positive regulation of long-chain fatty acid import across plasma membrane | biological process | ACSL5 |
| positive regulation of long-chain fatty acid import into cell | biological process | FABP3 |
| positive regulation of long-term neuronal synaptic plasticity | biological process | KIT, NPTN, NEURL1, EPHB2 |
| positive regulation of long-term synaptic depression | biological process | KCNB1, ADCY8, PPP1R9A, GRID2 |
| positive regulation of long-term synaptic potentiation | biological process | NPTN, STAU1, EPHB2, LGMN, CHRNA7, SQSTM1, ADCY8, ZDHHC2, MME, AKAP5, INS, DRD2, CRTC1, NRGN, ADORA2A, SHISA7, RELN |
| positive regulation of low-density lipoprotein particle receptor biosynthetic process | biological process | SCAP, CNPY2, FGF21, HNRNPK |
| positive regulation of low-density lipoprotein particle receptor catabolic process | biological process | APOE, PCSK9, ABCA2 |
| positive regulation of lung ciliated cell differentiation | biological process | FOXJ1 |
| positive regulation of lung goblet cell differentiation | biological process | IL13 |
| positive regulation of luteinizing hormone secretion | biological process | LEP, KISS1, SMAD4, FOXL2 |
| positive regulation of lyase activity | biological process | FXN, FTMT |
| positive regulation of lymphangiogenesis | biological process | CCBE1, VEGFC |
| positive regulation of lymphocyte apoptotic process | biological process | FAS, P2RX7 |
| positive regulation of lymphocyte differentiation | biological process | STAT5B, XRCC6, PRKDC, NCKAP1L, INPP5D |
| positive regulation of lymphocyte migration | biological process | MADCAM1, JAM2 |
| positive regulation of lymphocyte proliferation | biological process | IL12A, TLR4, TAC1, ZNF335, MPL, FGF10 |
| positive regulation of lymphotoxin A biosynthetic process | biological process | CD86 |
| positive regulation of lysosomal membrane permeability | biological process | MT3 |
| positive regulation of lysosomal protein catabolic process | biological process | LDLR, LRP2, LRP1 |
| positive regulation of lysosome organization | biological process | GRN |
| positive regulation of macroautophagy | biological process | DCN, HIF1A, KDR, PAFAH1B2, GBA, WAC, TBK1, SCOC, TRIM13, SESN3, C9orf72, MAP3K7, GNAI3, TSC1, BNIP3L, GPSM1, SUPT5H, RUFY4, PINK1, IKBKG, BNIP3, LARP1, PRKAA2, STING1, TSC2, SESN2, PIM2 |
| positive regulation of macrophage activation | biological process | HSPD1, SPACA3, IL33, KARS1, IL13, HAVCR2, THBS1, PLA2G4A, IL1RL1, TNIP2, LBP, IL4R, TLR6 |
| positive regulation of macrophage apoptotic process | biological process | CDKN2A, MEF2C |
| positive regulation of macrophage chemotaxis | biological process | CCL5, CSF1, CX3CL1, KARS1, PTK2, IL34, THBS1, MDK, AKIRIN1, C3AR1, MSTN, RARRES2, CMKLR1, CSF1R, C5AR1 |
| positive regulation of macrophage colony-stimulating factor production | biological process | ISL1 |
| positive regulation of macrophage colony-stimulating factor signaling pathway | biological process | CSF1 |
| positive regulation of macrophage cytokine production | biological process | TLR4, SEMA7A, CD74, RTN4, GPRC5B, SPON2, CD36 |
| positive regulation of macrophage derived foam cell differentiation | biological process | APOB, CSF1, PLA2G2A, PLA2G10, LPL, PRKCH, PLA2G3, PF4, AGTR1, MAPK9, PLA2G5, ALOX15B, AGT, CD36 |
| positive regulation of macrophage differentiation | biological process | LIF, CASP8, RB1, CSF1, IL34, FADD, TRIB1, PF4, HCLS1, CALCA, ID2, ROR2 |
| positive regulation of macrophage fusion | biological process | TYROBP, ADAM9, TREM2, DCSTAMP |
| positive regulation of macrophage inflammatory protein 1 alpha production | biological process | MCOLN2 |
| positive regulation of macrophage migration | biological process | RTN4, MMP14 |
| positive regulation of macrophage migration inhibitory factor signaling pathway | biological process | CXCR4, CD74 |
| positive regulation of macrophage proliferation | biological process | PTK2, IL34, CSF1R |
| positive regulation of macrophage tolerance induction | biological process | IRAK3 |
| positive regulation of macropinocytosis | biological process | APPL2, APPL1 |
| positive regulation of maintenance of mitotic sister chromatid cohesion | biological process | SLF2, NSMCE2, SMC5, MACROH2A1, SLF1 |
| positive regulation of male germ cell proliferation | biological process | CIB1 |
| positive regulation of male gonad development | biological process | WT1, SOX9, NR5A1, SRY, DMRT1, SEMA3A, ZFPM2, CITED2, DHX37 |
| positive regulation of male mating behavior | biological process | HDAC4, HDAC2 |
| positive regulation of mammary gland epithelial cell proliferation | biological process | KDM5B, RTN4, IQGAP3, CCND1, MST1, RREB1, ZNF703, MST1L |
| positive regulation of mammary stem cell proliferation | biological process | LBH |
| positive regulation of MAP kinase activity | biological process | EGFR, EGF, TGFB1, TNF, VEGFA, KITLG, ERBB2, FLT1, S100A12, EZH2, FGFR1, GH1, KIT, SRC, MIF, ELANE, PDCD10, IQGAP1, MAGED1, PDGFB, IRAK1, KRAS, PDGFD, RASGRP1, TAB1, IL34, AJUBA, NOD2, NEK10, ADRA2A, PSEN1, PDGFA, TPD52L1, AKAP13, DIRAS2, PIK3CG, FGF18, ILK, PDE5A, PDGFRB, DIRAS1, HRAS, EDN1, MST1R, PDGFC, FGF2, CSK, ADAM8, PIK3R6, PIK3R5, CD40, FGF1, EDN3, LRRK2, ROBO1, HTR2B |
| positive regulation of MAPK cascade | biological process | IL6, IL6R, LIF, TNFRSF1B, IL11, FAS, IGF2, FLT1, FGFR2, FGFR3, KDR, ITGB1, FGFR1, CTNNB1, LEP, IGF1, INSR, KIT, F2R, SOX2, CDC42, FGF9, KISS1, TIMP2, TNFRSF25, IAPP, RYK, ROR1, NMNAT1, GRM4, BANK1, NOX1, CD74, IQGAP1, GSDME, SHC1, DUSP19, DNAJC27, LILRA5, GPR37L1, PDGFB, DAB2IP, JCAD, EFNA1, ROCK2, FLT4, MYDGF, PSAP, ADRB2, ADRB3, TEK, NTRK2, WWC1, RIT2, PELI2, ROCK1, PTPRC, ADRA2A, HMGB1, ADRA1A, CAV2, CDON, PDGFA, SORBS3, NDST1, NENF, IGFBP4, TRAF7, KSR1, ZNF622, C1QTNF1, TMEM106A, OSM, PRKCE, LAMTOR1, LPAR1, P2RX7, ADRA2B, AVPR1B, ILK, TLR9, MOS, CD4, RET, ADRA1D, LPAR3, BCAR3, HRAS, BMP2, FGF2, EPHA8, ADRA1B, ADRA2C, ALOX12B, INS, ROR2, DHX33, DOK5, MMP8, THPO, TRIM5, FGF10, CD36, GPER1 |
| positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway | biological process | FGFR1, FGF23, FGF21, KL |
| positive regulation of mast cell activation | biological process | TSLP, CD226, CRLF2 |
| positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway | biological process | NR4A3 |
| positive regulation of mast cell activation involved in immune response | biological process | SPHK2 |
| positive regulation of mast cell chemotaxis | biological process | VEGFA, CCL5, SWAP70, VEGFC, VEGFB |
| positive regulation of mast cell cytokine production | biological process | BCL10, FCER1G, NR4A3 |
| positive regulation of mast cell degranulation | biological process | IL4, SPHK2, SYK, IL13, GAB2, GATA2, FGR, FCER1G, ADORA2B, IL4R |
| positive regulation of mast cell proliferation | biological process | KITLG, LYN |
| positive regulation of maternal process involved in parturition | biological process | PTAFR |
| positive regulation of MDA-5 signaling pathway | biological process | DHX58, ANKRD17, DDX60 |
| positive regulation of mediator complex assembly | biological process | MED25 |
| positive regulation of megakaryocyte differentiation | biological process | SCIN, PITHD1, MTURN, GATA2, TESC, FAXDC2, THPO |
| positive regulation of meiosis I | biological process | DMRT1, PIWIL2 |
| positive regulation of meiotic cell cycle | biological process | INSR, LFNG |
| positive regulation of meiotic DNA double-strand break formation | biological process | ANKRD31 |
| positive regulation of meiotic nuclear division | biological process | DAZL, WNT4, SIRT2 |
| positive regulation of melanin biosynthetic process | biological process | ZEB2, ASIP, GIPC1, APPL1, CDH3, TYRP1 |
| positive regulation of melanocyte differentiation | biological process | BCL2, KITLG, ZEB2, ADAMTS20, ADAMTS9 |
| positive regulation of melanosome transport | biological process | CDH3 |
| positive regulation of membrane depolarization during cardiac muscle cell action potential | biological process | ANK3 |
| positive regulation of membrane hyperpolarization | biological process | AGT |
| positive regulation of membrane permeability | biological process | DEFA5 |
| positive regulation of membrane potential | biological process | ANK3, GLRX, UCN3, PIAS3, SLC34A1 |
| positive regulation of membrane protein ectodomain proteolysis | biological process | TNF, IFNG, IL1B, APOE, TNFRSF1B, SNX33, ADRA2A, SNX9, GPLD1, NRDC, ADAM9, FURIN, ADAM8, SH3D19, PACSIN3 |
| positive regulation of membrane tubulation | biological process | SH3GLB1, SH3GL2, PLEKHM2, ASAP1 |
| positive regulation of memory T cell differentiation | biological process | IL23A, CD46, IL12RB1, IL23R, TNFSF4 |
| positive regulation of mesenchymal cell apoptotic process | biological process | MSX1, MSX2 |
| positive regulation of mesenchymal cell proliferation | biological process | VEGFA, SOX9, FGFR2, STAT1, FGFR1, CTNNB1, SHH, FGF9, TP63, MYC, MYCN, BMPR1A, IRS2, PRRX1, SMO, PDGFA, FOXP2, LRP5, CHRD, TGFBR2, FOXF1, IHH |
| positive regulation of mesenchymal cell proliferation involved in ureter development | biological process | SHH, SIX1 |
| positive regulation of mesenchymal stem cell differentiation | biological process | SOX9, SOX5, SOX6, LTBP3 |
| positive regulation of mesenchymal stem cell migration | biological process | CXCR4, ACKR3 |
| positive regulation of mesenchymal stem cell proliferation | biological process | BMP4, CITED1, CCNE1, VEGFC, LTBP3 |
| positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological process | LIF, GDNF, PAX8 |
| positive regulation of mesoderm development | biological process | ETV2, MIXL1 |
| positive regulation of mesodermal cell fate specification | biological process | WNT3A |
| positive regulation of metabolic process | biological process | PIGA, PYURF |
| positive regulation of metalloendopeptidase activity | biological process | STAT3, MBP |
| positive regulation of metallopeptidase activity | biological process | ANTXR1, KARS1, DDRGK1, CLDN4 |
| positive regulation of metanephric cap mesenchymal cell proliferation | biological process | MYC |
| positive regulation of metanephric DCT cell differentiation | biological process | PAX8 |
| positive regulation of metanephric glomerular visceral epithelial cell development | biological process | ADIPOQ |
| positive regulation of metanephric glomerulus development | biological process | RET |
| positive regulation of metanephric mesenchymal cell migration | biological process | PDGFB |
| positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway | biological process | PDGFB, PDGFA, PDGFRB |
| positive regulation of metanephric ureteric bud development | biological process | WT1, BASP1 |
| positive regulation of metaphase/anaphase transition of meiosis I | biological process | MAPK15 |
| positive regulation of methylation-dependent chromatin silencing | biological process | DNMT1, SETDB2, RESF1, TASOR, ATF7IP, SETDB1, PPHLN1, MORC2 |
| positive regulation of MHC class I biosynthetic process | biological process | HSPH1, IFNL1, NLRP12, CIITA |
| positive regulation of MHC class II biosynthetic process | biological process | IFNG, IL4, IL10, TLR4, JAK2, XBP1, CDK5R1, TMEM106A, CIITA, AZU1 |
| positive regulation of microglial cell activation | biological process | CCL3, CTSC, STAP1, TREM2, TAFA3, MMP8, LRRK2, TTBK1 |
| positive regulation of microglial cell mediated cytotoxicity | biological process | STAP1, ITGAM, TYROBP |
| positive regulation of microglial cell migration | biological process | CSF1, CCL3, P2RY12, CX3CR1, TREM2, P2RX4 |
| positive regulation of microtubule binding | biological process | PPP2CA, ABL1 |
| positive regulation of microtubule depolymerization | biological process | KATNB1, SPAST |
| positive regulation of microtubule motor activity | biological process | MTCL1 |
| positive regulation of microtubule nucleation | biological process | MECP2, PDE4DIP, CKAP5, HSPA1A, HSPA1B |
| positive regulation of microtubule plus-end binding | biological process | MAPRE3, MAPRE1 |
| positive regulation of microtubule polymerization | biological process | DRG1, TOGARAM1, NIN, RPS3, ARL2, CDK5RAP2, CAV3, ANKRD53, CDK5R1, AKAP9, CLIP1, CDKN1B, RAC1, NUMA1, SLAIN2, MAPRE1, NAV3, PSRC1, FES, CLASP1, MAP1B |
| positive regulation of midbrain dopaminergic neuron differentiation | biological process | DKK1 |
| positive regulation of mini excitatory postsynaptic potential | biological process | ADRB2 |
| positive regulation of miRNA catabolic process | biological process | ZC3H12A, PNPT1 |
| positive regulation of miRNA mediated inhibition of translation | biological process | AGO2 |
| positive regulation of miRNA metabolic process | biological process | RELA, HRAS |
| positive regulation of mismatch repair | biological process | HMGB1, HDAC10, PRKCG |
| positive regulation of mitochondrial calcium ion concentration | biological process | RAP1GDS1, BNIP3, MICU2, BCAP31, FIS1, MCUR1, TGM2, MICU1, ATP2A1, SLC25A23 |
| positive regulation of mitochondrial depolarization | biological process | DCN, KDR, RACK1, MLLT11, P2RX7, CCK, MYOC |
| positive regulation of mitochondrial DNA metabolic process | biological process | PPARGC1A |
| positive regulation of mitochondrial DNA replication | biological process | STOML2 |
| positive regulation of mitochondrial electron transport, NADH to ubiquinone | biological process | PARK7, PINK1, ISCU |
| positive regulation of mitochondrial fission | biological process | DCN, KDR, DNM1L, MFF, PRKN, MARCHF5, DDHD2, DDHD1, PINK1, BNIP3, MIEF2, SPIRE1, MIEF1, FIS1, MUL1, VPS35 |
| positive regulation of mitochondrial fusion | biological process | PRKN, ZDHHC6, OPA1 |
| positive regulation of mitochondrial membrane permeability | biological process | BNIP3L, SLC9A1, HEBP2, TP53 |
| positive regulation of mitochondrial membrane permeability involved in apoptotic process | biological process | BAX, BCL2L11, ATF2, STPG1 |
| positive regulation of mitochondrial membrane potential | biological process | GSK3B, BAD, CTNS, NNT, STOML2, BID, MFN1, TCL1A, AKT2 |
| positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | BAX, BAK1, GSK3B, ATP5IF1, ZNF205, BID, BOK, SIVA1, CHCHD10, HIP1R |
| positive regulation of mitochondrial RNA catabolic process | biological process | GRSF1, SUPV3L1, PNPT1 |
| positive regulation of mitochondrial transcription | biological process | CHCHD10 |
| positive regulation of mitochondrial translation | biological process | C1QBP, CDK5RAP1, RPUSD4, RPUSD3, UQCC1, FASTKD2, TRMT10C, RCC1L, MRPS27, UQCC2, RMND1, TRUB2, FASTKD3, NGRN, MPV17L2 |
| positive regulation of mitochondrion organization | biological process | HTRA2, PPARGC1A, TREM2 |
| positive regulation of mitophagy | biological process | VPS13D |
| positive regulation of mitophagy | biological process | HIF1A, PARK7, PRKN, BNIP3, HTT, FBXO7, CAMKK2 |
| positive regulation of mitotic cell cycle | biological process | BRCA2, BIRC5, CDK1, CCNB1, MDM2, APP, PTPN11, RPS6KB1, STAT5B, NKX3-1, DYNLT3, ASNS, FOXA1, LGMN, USP22, EIF4EBP1, PKN2, USP2, EIF4E, TTL, ABL1, DUSP3, MEIS2, SMOC2, CDC25B, FGF10 |
| positive regulation of mitotic cell cycle phase transition | biological process | TMOD3 |
| positive regulation of mitotic cell cycle spindle assembly checkpoint | biological process | NDC80, PCID2, MAD2L1, DYNC1LI1, GEN1, TPR, XRCC3 |
| positive regulation of mitotic cell cycle, embryonic | biological process | HES1 |
| positive regulation of mitotic centrosome separation | biological process | NSFL1C, UBXN2B |
| positive regulation of mitotic cohesin loading | biological process | NIPBL |
| positive regulation of mitotic cytokinetic process | biological process | NUP62, KIF20B |
| positive regulation of mitotic metaphase/anaphase transition | biological process | RB1, NSMCE2, CDC16, DLGAP5, CDC23, ESPL1, ANAPC5, ANAPC7, ANAPC11, CDC27, ANAPC4 |
| positive regulation of mitotic nuclear division | biological process | EGF, IL1B, IGF2, DMRT1, IL1A, IGF1, INSR, FGF8, NUSAP1, PDGFB, TGFA, NUP62, PHIP, SMPD3, EREG, RGCC, LRP5, DRD3, PDGFRB, BTC, EDN1, CD28, INS, EDN3 |
| positive regulation of mitotic spindle elongation | biological process | NUMA1 |
| positive regulation of monocyte aggregation | biological process | CD44, HAS2, NR4A3 |
| positive regulation of monocyte chemotactic protein-1 production | biological process | IL1B, LGALS9, SYK, ADIPOQ, TWIST1, MCOLN2, AGER |
| positive regulation of monocyte chemotaxis | biological process | SERPINE1, CCL5, AIF1, CCR1, CCL1, ANO6, CREB3, LGMN, HMGB1, S100A7, PLA2G7, FPR2, MOSPD2, CXCL12, CXCL10 |
| positive regulation of monocyte differentiation | biological process | CSF1, CD74, CTNNBIP1, IL34, ACIN1, ZFP36L1, CD4, FES, DCSTAMP |
| positive regulation of monocyte extravasation | biological process | PDGFD, AGER |
| positive regulation of mononuclear cell migration | biological process | TNF, IL4, CCL27, AIF1 |
| positive regulation of mononuclear cell proliferation | biological process | IL12A, CSF1 |
| positive regulation of monooxygenase activity | biological process | GDNF, POR |
| positive regulation of monophenol monooxygenase activity | biological process | CDH3 |
| positive regulation of motile cilium assembly | biological process | ZMYND10 |
| positive regulation of mRNA 3'-end processing | biological process | CCNB1, NCBP2, DHX36, PAF1, NCBP1, CDC73, LEO1 |
| positive regulation of mRNA 3'-UTR binding | biological process | CDK9 |
| positive regulation of mRNA binding | biological process | FMR1, EIF3E, EIF3D, EIF3C, LARP6 |
| positive regulation of mRNA catabolic process | biological process | CNOT1, HNRNPR, ZC3H12A, CNOT8, ZC3HAV1, UPF1, GTPBP1, PRR5L, RC3H1, PNPT1, MOV10, KHSRP |
| positive regulation of mRNA cleavage | biological process | NUDT21 |
| positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response | biological process | HSPA1A |
| positive regulation of mRNA modification | biological process | APOBEC1 |
| positive regulation of mRNA polyadenylation | biological process | NUDT21, CPEB1, CPEB3 |
| positive regulation of mRNA splicing, via spliceosome | biological process | RBMX, HSPA8, SNRNP70, PRPF19, TRA2B, RBM3, NCBP1, PRDX6, TRA2A, SLC39A5, CELF4, SNW1, NUP98, SF3B4, NCL, THRAP3, RBMXL1 |
| positive regulation of mucus secretion | biological process | CYBA, ATG5, SYTL2, PRKCE, ALOX12B, P2RY2 |
| positive regulation of multicellular organism growth | biological process | BCL2, HSF1, GHRL, GH1, EZR, CHD7, CSF1, PPIB, BBS2, STAT5B, PLS1, MKKS, GHSR, BBS4, GHRHR, FOXS1, SMO, NIPBL, GHR, ATP8A2, POU3F2, GPAM, GPR21, SH3PXD2B, DRD2, DIO3, SLC6A3, SPTBN4, VIL1 |
| positive regulation of muscle atrophy | biological process | MYOG, FOXO3 |
| positive regulation of muscle cell differentiation | biological process | CTNNB1, CDC42, MEF2A, MAPK14, SETD3, MAPK11, CTNNA1, BNIP2, CTNNA2, TARBP2, MEF2C, CDON, ABL1, RBM4, MAPK12, MYOD1, MYOG, CDH15, CAMK1, MAML1 |
| positive regulation of muscle hyperplasia | biological process | AIF1 |
| positive regulation of muscle tissue development | biological process | PPARGC1A |
| positive regulation of myelination | biological process | HGF, NRG1, DICER1, WASF3, RNF10, PARD3, EGR2, S100B, ITGAX, DAG1, CST7, SLC25A12, TPPP, MAG, TENM4, NCMAP, MYRF, ZNF488 |
| positive regulation of myeloid cell apoptotic process | biological process | ADIPOQ |
| positive regulation of myeloid cell differentiation | biological process | LEP, HOXA5, CSF3, FES, JAG1 |
| positive regulation of myeloid dendritic cell activation | biological process | CD2, CLEC4D |
| positive regulation of myeloid dendritic cell chemotaxis | biological process | CCL21 |
| positive regulation of myeloid dendritic cell cytokine production | biological process | DDX1, DHX36, DDX21, MAVS, TICAM1 |
| positive regulation of myeloid leukocyte cytokine production involved in immune response | biological process | MIF |
| positive regulation of myeloid leukocyte differentiation | biological process | KITLG, CD101 |
| positive regulation of myoblast differentiation | biological process | MAPK14, BTG1, MEF2C, ZFHX3, AKIRIN1, CDON, CSRP3, MAP3K5, RBM24, HIF1AN, ILK, RANBP3L, TNFSF14, MYOD1, MYOG, SMYD1, FLT3LG, RIPOR2 |
| positive regulation of myoblast fusion | biological process | IL4, GDF15, MAPK14, CAPN2, CD53, NFATC2, SCGB3A1, FLOT1, EHD2, ADGRB1, TNFSF14, MYOD1, MYOG, IL4R, FLT3LG, RIPOR2 |
| positive regulation of myoblast proliferation | biological process | MEGF10, PAX7, PPARD, PAXBP1, SOX15 |
| positive regulation of myosin light chain kinase activity | biological process | IL1B |
| positive regulation of myosin-light-chain-phosphatase activity | biological process | PPP1R12A |
| positive regulation of myotome development | biological process | DMRT2 |
| positive regulation of myotube differentiation | biological process | MTOR, MAPK14, MAMSTR, CAV3, MMP14, RBM24, MYOG, SMYD1, MAML1 |
| positive regulation of N-terminal peptidyl-lysine acetylation | biological process | SOX4 |
| positive regulation of NAD(P)H oxidase activity | biological process | GNAI2, GNAI3, CYBA, AGTR1, RFK, AGT |
| positive regulation of NAD+ ADP-ribosyltransferase activity | biological process | TGFB1, HMGN1, DTX3L |
| positive regulation of natural killer cell activation | biological process | IL12A, IL23A, RASGRP1, TYROBP, TICAM1 |
| positive regulation of natural killer cell chemotaxis | biological process | CCL5, CCL3, CCL7, CXCL14 |
| positive regulation of natural killer cell cytokine production | biological process | CD226, CD160, CLNK, HLA-F |
| positive regulation of natural killer cell degranulation | biological process | AP1G1, LAMP1, CD160, HLA-F |
| positive regulation of natural killer cell differentiation | biological process | AXL, GAS6, IL15, STAT5B, RASGRP1, FLT3LG, ZBTB1 |
| positive regulation of natural killer cell mediated cytotoxicity | biological process | IL12A, IL21, STAT5B, AP1G1, CD226, NCR3, RASGRP1, IL18RAP, RAET1E, LAMP1, SLAMF6, CRTAM, CD160, PVR, VAV1 |
| positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target | biological process | IL12A, CD226, CRTAM, PVR |
| positive regulation of natural killer cell mediated immune response to tumor cell | biological process | CD160 |
| positive regulation of natural killer cell mediated immunity | biological process | HLA-E, SH2D1B |
| positive regulation of natural killer cell proliferation | biological process | IL18, IL23A, IL15, STAT5B, IL23R, FLT3LG |
| positive regulation of necroptotic process | biological process | ZBP1, RIPK3 |
| positive regulation of necrotic cell death | biological process | IL17A, HEBP2, BNIP3, MT-CO2, MT3, RIPK3 |
| positive regulation of nephron tubule epithelial cell differentiation | biological process | LHX1 |
| positive regulation of neural precursor cell proliferation | biological process | FZD9, NAP1L1, GNAI2, ELL3, WNT3A, MDK, ASCL1, CDON, INSM1, RASSF10, CTSZ, PROX1, DISP3, NES, LHX2 |
| positive regulation of neuroblast proliferation | biological process | VEGFA, SOX10, HIF1A, CTNNB1, SHH, CX3CL1, GLI3, ASPM, SMARCD3, DISC1, NOTCH1, FZD3, ZNF335, SMO, OTP, FOXG1, CX3CR1, VEGFC, DRD2, DCT |
| positive regulation of neurofibrillary tangle assembly | biological process | APOE, CLU |
| positive regulation of neurogenesis | biological process | LIG4, MTOR, XRCC2, SPEN, NUMBL, CXCR4, XRCC5, NAP1L1, MAN2A1, STAR, NUMB, FAIM, ELL3, TRIM32, ZNF335, ASCL1, SOX11, SRRT, LRP2, RASSF10, CX3CR1, SNW1, BHLHB9, MME, RGS14, SERPINF1, DRD2, HAP1, GPER1 |
| positive regulation of neuroinflammatory response | biological process | NUPR1, TREM2, MMP8, TNF |
| positive regulation of neuromuscular synaptic transmission | biological process | RAPSN |
| positive regulation of neuron apoptotic process | biological process | TP53, BAX, CASP3, FASLG, GSK3B, CASP9, ATM, CTNNB1, CDC42, PRNP, HDAC4, DDIT3, RAPSN, PIN1, BCL2L11, CCL3, NUPR1, NQO1, SRPK2, AIFM1, ATF4, MAP2K4, CASP2, ASCL1, TFAP2A, TGFB2, CDK5R1, FIS1, GRIK5, CDC34, ATF2, PITX3, GRN, PAK3, UBE2M, EPHA7, CTSZ, CDK5, BACE1, FOXO3, NQO2, PCSK9, NF1, GRIK2, TNF |
| positive regulation of neuron death | biological process | APOE, GSK3B, ATM, CLU, MTOR, BAD, PRNP, DDIT3, CAPN2, AIMP2, SNCA, TP53BP2, ZNF746, EGR1, FCGR2B, PICALM, ITGAM, SARM1, DKK1, ELK1, TYROBP, EIF2S1, ABL1, MAP3K5, GRIN2B, FOS, PPP1R13B, ITGB2, EFNB2, SSH1, CDK5, C1QA |
| positive regulation of neuron differentiation | biological process | IFNG, IL6, DNMT3B, ITGB1, FGFR1, BMP7, BMP4, CCL5, ETV5, TIMP2, SOCS2, NKX2-2, PRPF19, RARB, DMD, HOXD3, BCL6, PHOX2B, CYB5D2, BRINP2, FOXA1, SH3GL3, NEUROG1, KDM4C, PCP4, REST, ZC4H2, MEF2C, TRIM32, FEZ1, HMG20B, MMD, NRCAM, ASCL1, CDON, SOX11, NEUROD1, GDPD5, NCOA1, CPNE1, ECT2, ZEB1, FOXG1, ARHGEF2, TCF4, GATA2, BMP6, IRX3, GPRC5B, NAP1L2, ADRA2B, TRPC5, BMP2, DUOXA1, GDF7, TGIF2, ADRA2C, NKX2-5, VWC2, IMPACT, BRINP1, EPO, GLI2, KCTD11, MMD2, NBL1, CXCL12, VWC2L, BEND6, MAP1B, RARA, GDF5, LIN28A |
| positive regulation of neuron maturation | biological process | BCL2, MTOR, OPA1, MAP3K13, RET |
| positive regulation of neuron migration | biological process | SEMA3A, NSMF, SHTN1, RAPGEF2, DAB2IP, MDK, ZNF609, SRGAP2C, NIPBL, KIF20B, ARHGEF2, SEMA6A, PLAA, FBXO31 |
| positive regulation of neuron projection arborization | biological process | FZD4, DVL1, GRIP1, MAP3K13, DVL2, DLG4, DVL3 |
| positive regulation of neuron projection development | biological process | LIF, ITGB1, FGFR1, MTOR, ADAMTS1, BMP4, RAP1A, NTRK1, KATNB1, SNX3, ROR1, CAMK2B, FBXO38, GPC2, BCL11A, BAIAP2, NPTN, DMD, ATF1, WASHC5, PTK7, MOB2, MARK2, RAPGEF2, NCK1, PTN, LTK, DPYSL3, DAB2IP, ANKRD27, DVL1, SCARB2, PRKD1, SETX, CAMK1D, NDRG4, ARHGAP35, ADNP, DISC1, NEGR1, PLA2G3, MDK, CNTN1, NTRK2, CREB3L2, RIT2, FEZ1, SCN1B, ARSB, RAPGEF1, CFLAR, KIDINS220, CNR1, RGS2, EP300, TIAM1, TMEM30A, ATP8A2, RRN3, ENC1, ALKAL2, RETREG3, LYN, NME2, ABL2, PPP1R9A, CBFA2T2, LRP1, ALKAL1, SERPINI1, FUT9, RET, TWF2, AVIL, ATP1B2, P3H1, PLXNB3, NME1, EPHA3, DDX56, SERPINF1, NCKIPSD, APBB1, PLXNB2, AP2A1, EPO, FES, ITGA3, ROR2, PTK6, TRIM67, AMIGO1, CAMK1, SCARF1, SF3A2, PLK5, TENM3, FZD1, AGT, PTK2B, RELN, ANKRD1, ZNF804A, MAGI2, NDNF, Grn |
| positive regulation of neuron projection regeneration | biological process | HGF |
| positive regulation of neurotransmitter secretion | biological process | DTNBP1, STX1B, UNC13A, BAIAP3, GPER1 |
| positive regulation of neurotransmitter uptake | biological process | PRKN |
| positive regulation of neurotrophin production | biological process | HAP1 |
| positive regulation of neurotrophin TRK receptor signaling pathway | biological process | CYFIP2, TMEM108, CYFIP1, WASF1, NTF3 |
| positive regulation of neutrophil activation | biological process | IL16 |
| positive regulation of neutrophil apoptotic process | biological process | ANXA1, HCAR2, FCAR, PIK3CD |
| positive regulation of neutrophil chemotaxis | biological process | IL1B, CXCL8, IL23A, EDNRA, C1QBP, CD74, CAMK1D, MDK, TIRAP, CXCR2, RAC1, RAC2, C3AR1, CCL19, CCR7, NCKAP1L, EDN1, DAPK2, THBS4, DYSF, MOSPD2, LBP, CCL21, RIPOR2, C5AR1 |
| positive regulation of neutrophil degranulation | biological process | ITGAM, ITGB2, PTAFR |
| positive regulation of neutrophil differentiation | biological process | EVI2B |
| positive regulation of neutrophil extravasation | biological process | IL1R1, MDK, CD99L2, ADAM8, RIPOR2 |
| positive regulation of neutrophil mediated killing of fungus | biological process | POMC |
| positive regulation of neutrophil migration | biological process | RTN4 |
| positive regulation of NF-kappaB import into nucleus | biological process | TNF, IL1B, PTGS2, IL18, IL23A, TLR4, TLR2 |
| positive regulation of NF-kappaB transcription factor activity | biological process | TGFB1, TNF, IL1B, AMH, IL6, ICAM1, IL6R, AR, S100A12, CIB1, TLR4, TLR2, CLU, LTF, CAT, HSPA1A, HSPA1B, CLOCK, NTRK1, S100A9, MALT1, ROR1, TERF2IP, NPM1, LRRFIP1, TRIM13, CARM1, LGALS9, BCL10, TRIM25, ALK, MAP3K7, LAMTOR5, TRIM37, PRKCH, IRAK1, UBE2N, RPS27A, TRIM58, MYD88, IRAK2, KRAS, RPS3, PRKD1, TFRC, TRIM15, CAPN3, TAB1, PSMA6, NOD2, IL1RAP, RELA, PRKCQ, TRIM32, TRIM8, IRAK3, IL18RAP, TIRAP, CFLAR, PRKCB, NFKB2, ERC1, IKBKG, MAP3K13, FLOT1, PRDX3, UBE2V1, NLRP3, TAB2, TRIM38, AIM2, RIPK2, FER, ARHGEF2, RBCK1, TRAF6, UBC, CTH, CX3CR1, PRKCZ, PLA2G1B, S100A8, UBA52, CARD16, TAB3, BTK, TRIM62, IKBKB, ITGB2, EIF2AK2, TRADD, TRIM52, PIDD1, TLR9, MID2, RIPK3, TRAF5, RPS6KA5, EDA, PRKD2, PYCARD, TNFRSF11A, TRIM21, TLR3, TRIM14, RPS6KA4, ZBTB7A, UBB, ADAM8, TRAF1, DDRGK1, EDA2R, NOD1, INS, RNF31, DHX33, CD40, TRAF2, CARD14, CARD11, AGT, TRAPPC9, SLCO3A1, CAMK2A, TLR6, TRIM6, TRIM5, GREM1, CD36, CAV1, AGER, TICAM1, TRIM22, RHEBL1 |
| positive regulation of NFAT protein import into nucleus | biological process | TNF |
| positive regulation of NIK/NF-kappaB signaling | biological process | TNF, TERF2IP, DDX3X, LGALS9, IRAK1, RPS3, EDARADD, TRIM44, ZNF268, HAVCR2, AGO3, NOD2, CD86, RELA, PDCD4, PHB2, RC3H2, HMGB1, LRRC19, EP300, RC3H1, RBCK1, TRAF6, NFAT5, SASH1, CCL19, TREM2, PTP4A3, EIF2AK2, NLRP12, ILK, TRADD, TLR9, AGO1, TNFSF14, EDA, TLR7, EDN1, EDAR, TLR3, NOD1, ACTN4, CALR, NR3C2, MMP8, TRIP6, GREM1, AGER |
| positive regulation of nitric oxide biosynthetic process | biological process | EGFR, TNF, IFNG, IL1B, ESR1, IL6, ICAM1, PTGS2, HSP90AA1, AKT1, TLR4, CLU, MTOR, INSR, AIF1, KLF4, JAK2, DDAH1, NOS1AP, ASS1, PKD2, HBB, DDAH2, ITGB2, EDN1, P2RX4, KLF2, AGT, SMAD3, PTK2B, TLR6, MMP8, CD36, TICAM1, TRPV1 |
| positive regulation of nitric oxide mediated signal transduction | biological process | NOS1AP, GUCY1A2, GUCY1A1, INS |
| positive regulation of nitric oxide metabolic process | biological process | TMEM106A |
| positive regulation of nitric-oxide synthase activity | biological process | APOE, ESR1, HIF1A, TERT, AKT1, NOS1AP, KRAS, SCARB1, NUS1, NPR3, CALM3, DHFR, GCH1, NOD1, INS, FCER2, PTK2B, TNF, S100A1, HTR2B |
| positive regulation of nitric-oxide synthase biosynthetic process | biological process | KDR, TLR4, TLR2, JAK2, AKAP12, NOD2, NAMPT, MAP2K4, MAP2K6, TLR9, FCER2, LRRK2, CCL2 |
| positive regulation of nitrogen compound metabolic process | biological process | TNF |
| positive regulation of NK T cell activation | biological process | IL12A, IL23A, HSPH1, IL23R |
| positive regulation of NK T cell differentiation | biological process | AP3B1, AP3D1, TGFBR2, ZBTB16 |
| positive regulation of NK T cell proliferation | biological process | IL18, IL23A, RASAL3 |
| positive regulation of NLRP3 inflammasome complex assembly | biological process | TLR4, DDX3X, GBP5, STMP1, DHX33, TLR6, CD36 |
| positive regulation of NMDA glutamate receptor activity | biological process | EPHB2, PINK1, RGS9, CCL2 |
| positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological process | NODAL, SMAD2 |
| positive regulation of non-canonical Wnt signaling pathway | biological process | CSNK1E, CSNK1D, RSPO3 |
| positive regulation of non-canonical Wnt signaling pathway via JNK cascade | biological process | NKD1 |
| positive regulation of non-membrane spanning protein tyrosine kinase activity | biological process | STAP1, NTRK2, ADRA1A, DOCK3 |
| positive regulation of non-motile cilium assembly | biological process | 39326, SEPTIN9, ATMIN, WRAP73, RP1, HAP1, SEPTIN7 |
| positive regulation of norepinephrine secretion | biological process | OXTR, OXT, KCNB1 |
| positive regulation of Notch signaling pathway | biological process | STAT3, KIT, TP63, PDCD10, NOTCH2NLC, HES1, NOTCH2NLA, ZMIZ1, NEPRO, CREBBP, NOTCH1, NOD2, BMP2K, ASCL1, MFNG, ITGB1BP1, TGFB2, EP300, AAK1, RBPJ, SNW1, YAP1, MAML2, NOTCH4, CCN3, POGLUT1, TSPAN14, DLL1, MESP1, JAG2, KAT2B, JAG1, LFNG, EPN2, TSPAN5, MAML1, CNTN6, MAML3, FGF10 |
| positive regulation of Notch signaling pathway involved in heart induction | biological process | GATA5, ROBO2, MESP1, ROBO1 |
| positive regulation of nuclear cell cycle DNA replication | biological process | CDC7, DBF4, ATRX, WIZ, DBF4B, INO80 |
| positive regulation of nuclear receptor transcription coactivator activity | biological process | TACC1, CNOT9 |
| positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | PABPC1, NANOS2, NANOS1, NANOS3, CNOT1, DHX36, ZFP36L2, AGO2, TOB1, CPEB3, TNRC6B, ZFP36, ZFP36L1, TNRC6C |
| positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | PABPC1, CNOT1, POLR2G, BTG2, AGO2, TOB1, CPEB3, TNRC6B, ZFP36, TNRC6A, TNRC6C |
| positive regulation of nucleic acid-templated transcription | biological process | MED7, FUS, TAF12, SRCAP, TSG101, MTA3, ACTL6A, WDR77, HIF3A, HCFC2, RERE, AIP, TDRD3, ARL2BP, BUD31, JMY, SMARCE1, ZMIZ1, PDLIM1, NUPR1, ARID5B, SMARCD3, CCAR1, PSMC3IP, ID3, TRIM32, TAF11, PER2, ACTN2, DTX1, MED12L, SUPT7L, MYCBP, MED23, PRKCB, BIRC2, SRA1, UBE2L3, TRIP11, CCAR2, ACTN1, RUVBL1, MED26, NFKBIB, TADA2A, PML, NUP98, MNT, CITED2, E4F1, ZCCHC12, PQBP1, RIPK3, PMF1, PAGE4, PKN1, ACTL6B, ACTN4, RBPMS, MED27, ING4, ANKRD1 |
| positive regulation of nucleocytoplasmic transport | biological process | NEDD4 |
| positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway | biological process | TLR4, SLC46A2 |
| positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | TLR4, HSPA1A, HSPA1B |
| positive regulation of odontogenesis | biological process | TGFB1, EDNRA, CD34, EDN1, BMP2 |
| positive regulation of odontogenesis of dentin-containing tooth | biological process | CSF1, NGFR |
| positive regulation of oligodendrocyte apoptotic process | biological process | AKAP12 |
| positive regulation of oligodendrocyte differentiation | biological process | MTOR, PPARG, SHH, CXCR4, NKX2-2, HDAC2, PTN, ASPA, IL34, MDK, RHEB, DAG1, PTPRZ1, TENM4, ZNF365, ZNF488 |
| positive regulation of oligodendrocyte progenitor proliferation | biological process | GJC2, LRP2, LYN |
| positive regulation of oocyte development | biological process | PDE3A, PDE5A |
| positive regulation of oocyte maturation | biological process | SIRT2 |
| positive regulation of opsonization | biological process | MYO18A, PLA2G5 |
| positive regulation of organ growth | biological process | FGF8, YBX3, SERP1, IL7, CACNA2D2, SMO, YAP1, HLX, ARX, RAG2 |
| positive regulation of organelle assembly | biological process | STX18 |
| positive regulation of organelle organization | biological process | ANK1, SURF4, LMAN1, TMED9 |
| positive regulation of ossification | biological process | BMP4, OXT, TAC1, PTN, SOX11, TGFB2, NIPBL, P2RX7, WNT10B, BMP2, ZBTB16, TOB2 |
| positive regulation of osteoblast differentiation | biological process | IL6, IL6R, IL6ST, GNAS, BMP7, CTNNB1, LTF, IGF1, BMP4, HGF, BMPR2, GJA1, TP63, CCN1, GLI3, FBN2, NELL1, CTNNBIP1, ACVR1, PRKD1, BMPR1A, WNT7B, ATRAID, WNT4, GDPD2, SUCO, ACVR2B, MEF2C, FAM20C, SOX11, IFITM1, CLIC1, BMP6, ACVR2A, PDLIM7, LRP5, ILK, RUNX2, SFRP2, MSX2, ATP6AP1, WNT10B, BMP2, NPPC, JUND, CTHRC1, LRP3, JAG1, CCN4, CEBPD, SMAD5 |
| positive regulation of osteoblast proliferation | biological process | LTF, ITGAV, CCN1, HPSE, FBLN5, ABL1, LRP5, BMP2, CTHRC1, GATA1 |
| positive regulation of osteoclast development | biological process | SLC9B2, TYROBP, ATP6AP1, GPR68 |
| positive regulation of osteoclast differentiation | biological process | TNF, IFNG, GNAS, IL23A, CCL5, IL17A, CA2, CSF1, CCR1, IL20, IL23R, KLF10, TMEM64, TRAF6, FOS, POU4F1, TREM2, POU4F2, PPARGC1B |
| positive regulation of osteoclast proliferation | biological process | FLT3LG |
| positive regulation of otic vesicle morphogenesis | biological process | STOX1 |
| positive regulation of ovarian follicle development | biological process | ZP3 |
| positive regulation of ovulation | biological process | INHBA, PLAU |
| positive regulation of oxidative phosphorylation | biological process | NUPR1, MYOG |
| positive regulation of oxidative phosphorylation uncoupler activity | biological process | PARK7 |
| positive regulation of oxidative stress-induced cell death | biological process | FCAR |
| positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | SOD1, PARK7, NOX1, SFPQ |
| positive regulation of oxidative stress-induced neuron death | biological process | REST, TLR6 |
| positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway | biological process | MCL1, FBXW7 |
| positive regulation of oxidoreductase activity | biological process | NOD2, ABL1, ATP7A, ABL2, RIPK3 |
| positive regulation of oxygen metabolic process | biological process | MT3 |
| positive regulation of p38MAPK cascade | biological process | VEGFA, LEP, XDH, PJA2, GADD45B, KARS1, MAP3K4, ZC3H12A, EMC10, RELL2, GADD45A, MAP3K3, NCF1, MAP3K5, SASH1, PRMT1, MFHAS1, BMP2, MINK1, HAND2, AGER |
| positive regulation of pancreatic juice secretion | biological process | SCT, NR1H2 |
| positive regulation of pancreatic stellate cell proliferation | biological process | IL13 |
| positive regulation of pathway-restricted SMAD protein phosphorylation | biological process | TGFB1, INHBA, TGFB3, NODAL, BMP7, CSNK2B, HFE, GDF15, GDF9, BMP15, BMP4, BMPR2, INHA, ACVR1B, SMAD4, ACVR1, BMPR1A, DAB2, GDF11, BMP5, TGFB2, SDCBP, LEFTY1, TTK, TWSG1, TGFBR1, BMP6, ACVR2A, MSTN, BMP2, GDF3, ENG, ACVRL1, INHBC, INHBE, GDF7, GDF2, LEFTY2, GDF1, RBPMS, GDF5 |
| positive regulation of pattern recognition receptor signaling pathway | biological process | ZDHHC5 |
| positive regulation of penile erection | biological process | OXTR, OXT, EDNRB, P2RY1 |
| positive regulation of peptidase activity | biological process | APP, FN1, CLPX, FBLN1, PINK1, MAPK12, PCOLCE2, CTSH, PCOLCE, CAV1 |
| positive regulation of peptide hormone secretion | biological process | HFE, ILDR1, FGG, GRP, FGB, TFR2, FGA, RASL10B, INS |
| positive regulation of peptide secretion | biological process | S100A9, S100A8 |
| positive regulation of peptidyl-cysteine S-nitrosylation | biological process | ACE, NOS1AP |
| positive regulation of peptidyl-lysine acetylation | biological process | PRKAA2 |
| positive regulation of peptidyl-serine dephosphorylation | biological process | PPP1R15A, DUSP26 |
| positive regulation of peptidyl-serine phosphorylation | biological process | TGFB1, TNF, IL6, BCL2, LIF, VEGFA, CD44, IL11, AKT1, GSK3B, GAS6, PARK7, MIF, PIK3CA, RAF1, CDC42, IAPP, TERF2IP, TBK1, PDCD10, STK4, SNCA, PRKD1, HAX1, BAG4, TFRC, BRAF, PFN2, NRXN1, NTF4, WNT3A, NTRK2, AXIN1, UCN, STOX1, PINK1, ANGPT1, CNOT9, MAPKAP1, DOCK7, AKAP9, CREBL2, FNIP2, RIPK2, LATS1, OPRD1, FNIP1, MAD2L2, IRGM, MTCP1, OSM, HCLS1, TCL1A, HDAC6, SPRY2, RAMP3, CSF3, SFRP2, AVP, PRKD2, BCAR3, RAPGEF3, TCL1B, NTF3, SH2D3C, CALCR, CAPRIN2, SH2D3A, ARRB2, RPTOR, CAMK1, TRIM6, CAV1, TNKS1BP1 |
| positive regulation of peptidyl-serine phosphorylation of STAT protein | biological process | IFNG, LIF, IFNA1, IFNA8, IFNA10, RET, IFNA2, IFNA14, IFNW1 |
| positive regulation of peptidyl-threonine phosphorylation | biological process | EGF, TGFB1, MAPK1, GSK3B, BMP7, WNK3, CAB39, CEMIP, PRKAG2, CHI3L1, AXIN1, STOX1, CALM1, CALM2, CALM3, PLK1, RIPK2, S1PR2, IRGM, UBE2K, TRPC5, AZU1, RPTOR, TRIM6, TNKS1BP1 |
| positive regulation of peptidyl-tyrosine autophosphorylation | biological process | ACE, VEGFA, IQGAP1, GREM1 |
| positive regulation of peptidyl-tyrosine phosphorylation | biological process | EGF, TGFB1, TP53, IL4, IL6, ICAM1, IL6R, LIF, VEGFA, CD44, IL11, KITLG, IGF2, ITGB1, ITGA5, MTOR, GH1, IGF1, IL5, YES1, SRC, MIF, HGF, NRG1, TEX101, PRNP, AREG, JAK2, IL15, BANK1, CD74, TDGF1, ENPP2, PDGFB, CD81, EFNA1, ACVR1, HAX1, SYK, CSPG4, ADIPOQ, ADNP, SEMA4D, CNTN1, IL3, EFNA5, EHD4, PTPRC, TEC, ANGPT4, CD3E, ANGPT1, ITGB3, GHR, RIPK2, ABL1, ARHGEF2, HBEGF, OSM, HCLS1, BMP6, TNFRSF14, TREM2, VTN, CSF3, CD4, FGF7, MLST8, CCK, VEGFB, PECAM1, NTF3, THBS4, NRP1, LRP4, ARRB2, DGKQ, AGT, PTK2B, LRRK1, RELN, FGF10, GATA1, CD36, CD80 |
| positive regulation of PERK-mediated unfolded protein response | biological process | PTPN2, AGR2, BOK, TMEM33 |
| positive regulation of peroxisome proliferator activated receptor signaling pathway | biological process | LEP, ASXL2, LMO3, FABP5, STARD10, GPS2, PTGIS, CITED2, ALOX15B |
| positive regulation of phagocytosis | biological process | TNF, IL1B, GAS6, C3, RAP1A, SPACA3, SIRPB1, IL15, RAB27A, CD47, CAMK1D, LYAR, TULP1, BCR, ABR, LMAN2, IL15RA, FCGR2B, MFGE8, CYBA, APOA1, GATA2, SLC11A1, LRP1, IL2RB, FPR2, FCER1G, IL2RG, SFTPD, PLA2G5, PYCARD, AZU1, MBL2, ABCA7, CALR, MERTK, TUB, DOCK2, AHSG |
| positive regulation of phagocytosis, engulfment | biological process | PPARG, ANO6, STAP1, RAB31, ITGA2, GATA2, APPL2, TREM2, NCKAP1L, CD36 |
| positive regulation of phagosome maturation | biological process | PLA2G5 |
| positive regulation of phosphatase activity | biological process | RGN, CHP2, MTMR9, RIPK3, BMP2 |
| positive regulation of phosphate transmembrane transport | biological process | SLC34A1 |
| positive regulation of phosphatidic acid biosynthetic process | biological process | NR1H4 |
| positive regulation of phosphatidylcholine biosynthetic process | biological process | RAB38, CAPN2, ACSL3 |
| positive regulation of phosphatidylinositol 3-kinase activity | biological process | TGFB1, FLT1, FGFR3, KIT, SRC, CDC42, PDGFB, VAV3, PTK2, PRKD1, NOD2, TEK, IRS1, P2RY12, VAV2, LYN, PIK3R4, CCL19, FGR, PDGFRB, CCR7, FGF2, PDGFRA, EPHA8, CD19, PTK2B, TNFAIP8L3, AMBRA1, CCL21 |
| positive regulation of phosphatidylinositol 3-kinase signaling | biological process | DCN, FSHR, SOX9, FLT1, KDR, FGFR1, LEP, GH1, CAT, IGF1, KIT, CCL5, HGF, NRG1, F2R, ROR1, UBE3A, JAK2, PIK3R1, PDGFB, PPARD, NKX3-1, PTK2, PDGFD, HAX1, PIK3AP1, MYDGF, PTPN6, MAZ, SEMA4D, TEK, NTRK2, IRS2, NEDD4, SELP, PDGFA, ANGPT1, PRR5L, NCF1, EPOR, TGFB2, GAB1, BECN1, CBL, LYN, RGL2, OSM, HCLS1, PIK3CG, FGR, CSF3, ERBB3, PDGFRB, PIK3CD, PRR5, PDGFC, CD28, PDGFRA, NTF3, PLXNB1, F2, INS, EPO, ROR2, UNC5B, PIK3R5, SERPINA12, AGT, RELN, MYOC, TNF, GPER1, WNT16 |
| positive regulation of phosphatidylinositol biosynthetic process | biological process | HTR2C, ZP3, HTR2B |
| positive regulation of phospholipase A2 activity | biological process | AGTR1, AVPR1B, PLAA |
| positive regulation of phospholipase activity | biological process | FGFR2, FGFR3, FGFR1, CCN1, HPCA, ARHGAP6, PLA2G5, PDPK1 |
| positive regulation of phospholipase C activity | biological process | ESR1, FLT1, FGFR1, KIT, ABL2, PDGFRB, HRAS, FGF2, PDGFRA, NTF3, PTAFR |
| positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway | biological process | GRP, GPR27, F2 |
| positive regulation of phospholipid biosynthetic process | biological process | XBP1, FABP3, ADGRF5 |
| positive regulation of phospholipid efflux | biological process | APOE, APOA1, ABCA7 |
| positive regulation of phospholipid scramblase activity | biological process | PRKCD |
| positive regulation of phospholipid translocation | biological process | ATP8A2, ABCB4, ATP8A1 |
| positive regulation of phospholipid transport | biological process | DBI, PRELID1, TRIAP1, ABCB4, CETP |
| positive regulation of phosphoprotein phosphatase activity | biological process | JAK2, CALM1, CALM2, CALM3, VRK3, PPP1R15A, PDGFRB, MAGI2 |
| positive regulation of phosphorylation | biological process | EGFR, EGF, AR, CCL5, MIF, ITGA6, AREG, PTGES3, BTBD10, BCL10, GRB10, THBS1, FZD7, PSEN1, EREG, SDCBP, LYN, DSCAM, KCTD20, ILK, NCKAP1L, IFNA2, NRP1, ANG, PPARGC1B |
| positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues | biological process | CCNK |
| positive regulation of pigment cell differentiation | biological process | BLOC1S6 |
| positive regulation of pinocytosis | biological process | AXL, PPT1, ANKFY1, CLN3, ACTN4 |
| positive regulation of plasma cell differentiation | biological process | XBP1 |
| positive regulation of plasma membrane bounded cell projection assembly | biological process | PLEK2 |
| positive regulation of plasma membrane raft polarization | biological process | env |
| positive regulation of plasminogen activation | biological process | HPN, PLGRKT, F12, CLEC3B, MELTF |
| positive regulation of platelet activation | biological process | TLR4, PLEK, SELP, PLA2G4A |
| positive regulation of platelet aggregation | biological process | F11R, PDPN, DMTN |
| positive regulation of platelet formation | biological process | PRKDC, MPL |
| positive regulation of platelet-derived growth factor production | biological process | PTGS2, SERPINB7 |
| positive regulation of platelet-derived growth factor receptor signaling pathway | biological process | F3, SRC, F7 |
| positive regulation of platelet-derived growth factor receptor-beta signaling pathway | biological process | HIP1R |
| positive regulation of podosome assembly | biological process | TNF, IL5, SRC, ARHGEF5, MSN, MAPK9, CAPG, LCP1, FSCN1, ASAP1 |
| positive regulation of polarized epithelial cell differentiation | biological process | AHI1 |
| positive regulation of polyamine transmembrane transport | biological process | AZIN1, AZIN2 |
| positive regulation of polynucleotide adenylyltransferase activity | biological process | PABPN1 |
| positive regulation of positive chemotaxis | biological process | VEGFA, KDR, F3, F7, S1PR1, ITGA2, CDH13, SMAD3, CCR4 |
| positive regulation of postsynaptic cytosolic calcium concentration | biological process | SYNPO |
| positive regulation of postsynaptic membrane organization | biological process | APOE |
| positive regulation of potassium ion export across plasma membrane | biological process | ANO6, KCNIP2 |
| positive regulation of potassium ion import across plasma membrane | biological process | WNK3, WNK4, WNK1, WNK2, ATP1B1, ATP1B2, ATP1B3 |
| positive regulation of potassium ion transmembrane transport | biological process | KCNMB1, NOS1AP, KCNH2, KCNJ2, KCNE1, KCNC1, KCNC2, AMIGO1, EDN3, AKAP6 |
| positive regulation of potassium ion transmembrane transporter activity | biological process | ACTN2, ANK2, AKAP9, ATP1B1, ATP1B2, ATP1B3 |
| positive regulation of potassium ion transport | biological process | DPP6, KIF5B, FHL1, ACTN2, ADRA2A, ANK2, DLG1, DRD1 |
| positive regulation of presynaptic active zone assembly | biological process | NRXN1 |
| positive regulation of presynaptic cytosolic calcium concentration | biological process | CNR1, CDK5, CACNA1D, CACNB2 |
| positive regulation of presynaptic membrane organization | biological process | APOE, LRP4 |
| positive regulation of pri-miRNA transcription from RNA polymerase II promoter | biological process | HIF1A, TERT, STAT3, KLF4, SPI1, SMARCA4, SREBF2, PDGFB, GNL3, EGR1, BMPR1A, GATA3, RELA, ETS1, SMAD6, TGFB2, TEAD1, GATA2, KLF5, FOS, SREBF1, SRF, BMP2, NGFR, FGF2, FOXO3, SMAD3, TNF, TP53 |
| positive regulation of pro-B cell differentiation | biological process | NUDT21 |
| positive regulation of pro-T cell differentiation | biological process | ZBTB1 |
| positive regulation of production of miRNAs involved in gene silencing by miRNA | biological process | EGFR, MAP2K2, MAP2K1, TP53, LIN28A |
| positive regulation of progesterone biosynthetic process | biological process | PPARGC1A |
| positive regulation of programmed cell death | biological process | TNF, NTRK1, RARB, BNIP3, HTATIP2, CDKN1A, POU4F2, RARG, MARK4, LRRK2 |
| positive regulation of programmed necrotic cell death | biological process | TP53 |
| positive regulation of prolactin secretion | biological process | NMU, ABAT |
| positive regulation of prolactin signaling pathway | biological process | CREBRF |
| positive regulation of prostaglandin biosynthetic process | biological process | PTGS2, CD74, ANXA1, PLA2G3, AVP |
| positive regulation of prostaglandin secretion | biological process | IL1B, OXT, PLA2G10, MAP2K6, P2RX7, EDN1, P2RX4 |
| positive regulation of prostaglandin secretion involved in immune response | biological process | MIF |
| positive regulation of prostaglandin-E synthase activity | biological process | NOD2, ITGAM, ITGB2 |
| positive regulation of prostaglandin-endoperoxide synthase activity | biological process | NOD2, EDN1 |
| positive regulation of proteasomal protein catabolic process | biological process | FMR1, PSMC2, FBXW7, DAB2IP, PRKN, NUPR1, PSMC4, RNF40, OSBPL7, TREM2, PSMC1, DDRGK1 |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | AKT1, GSK3B, MDM2, CLU, SUMO1, RNF114, IL33, NUB1, PIAS1, CSNK1A1, KEAP1, DDA1, PLK2, COP1, TRIB3, RNF19A, RNF14, ARIH1, SOCS5, CSNK1E, SUMO2, RACK1, RNF144B, SOCS4, DVL1, PSMD10, ARIH2, GCLC, ZER1, CHFR, PRKN, DAB2, RNF217, ANKIB1, ZYG11B, STUB1, CBFA2T3, SIRT2, TRIB1, CSNK1D, RFPL1, PSEN1, ZFAND2A, PLK1, TAF1, DET1, FBXO22, RNF19B, RCHY1, SH3RF2, FAM122A, RNF144A, RBX1, TRIB2, KLHL40, DNAJB2, NKD2, DDRGK1, PRICKLE1, LRRK2, HSPA1A, HSPA1B, USP5 |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia | biological process | SIRT2, PLK3 |
| positive regulation of protein acetylation | biological process | TERF2IP, DDX3X, XBP1, KAT5, FAM161A, CEP295, TAOK1, ARNTL, RAPGEF3, CAMK1 |
| positive regulation of protein autophosphorylation | biological process | VEGFA, SRC, NBN, DDX3X, RAP2B, PDGFB, PDGFD, GPNMB, TAOK2, NEK10, MRE11, PDGFA, CALM1, CALM2, CALM3, RASSF2, TOM1L1, VEGFC, RAD50, RAP2A, PDGFC, INS, TNKS1BP1 |
| positive regulation of protein autoubiquitination | biological process | RBX1, LRRK2 |
| positive regulation of protein binding | biological process | TERT, GSK3B, B2M, HFE, BMP4, PKD1, TCF7L2, BAMBI, STK3, PLK2, MARK3, RPL11, TRIB3, STK4, PIN1, DTX3L, DERL1, AKTIP, RAPGEF2, CLDN5, PRKN, RAMP2, IDE, WNT3A, SPON1, MEN1, PSEN1, USP33, MFNG, EPB41L5, FLOT1, RALB, TAF1, RAN, EP300, TIAM1, HIPK2, RIPK2, ADD2, STING1, DACT1, NVL, VTN, CSF3, LRP1, ADD1, SPPL3, BMP2, CDK5, RAMP1, CAPRIN2, CTHRC1, LFNG, PLXND1, HIP1R, EPB41, AMFR, LRRK2, CAV1, TICAM1 |
| positive regulation of protein catabolic process | biological process | SOX9, GSK3B, GJA1, FOXO1, OAZ3, HECW2, PPP2R3A, ITCH, PLK2, SEC22B, VPS28, CREBRF, FZR1, NSF, STX5, DAB2IP, TNFSF12, RNF41, DTL, PRKN, C4BPB, IDE, ZNF268, TRIM32, TIPARP, NEDD4, GGA3, AXIN1, RAB7A, APC, CSNK2A1, MYLIP, CDKN1B, RHBDD1, NEDD4L, ATG4B, WWP2, HACE1, NDFIP1, WWP1, OAZ1, HECW1, SNF8, OAZ2, SORL1, BARD1, DACT1, RILP, GGA1, EGLN2, SMURF2, LPCAT1, APC2, GPC3, SGSM3, ASB5, DDB1, TNF, NKD1 |
| positive regulation of protein catabolic process in the vacuole | biological process | CD81, RNF128 |
| positive regulation of protein complex assembly | biological process | TGFB1, TNF, VEGFA, GSK3B, SUMO1, SLF2, CRBN, GNL3L, SH3GLB1, BCL2L11, RACK1, DAB2IP, RPS3, TFRC, WARS1, SYK, MPP7, AJUBA, HRK, TIRAP, CDC42EP2, BID, ICE1, FNIP2, SLF1, TRABD2B, FNIP1, FAF1, TCL1A, BMF, CDH5, CCK, BIK, TPPP, RHOC, TRABD2A, SPIDR |
| positive regulation of protein complex disassembly | biological process | TNF, BNIP3 |
| positive regulation of protein deacetylation | biological process | DYRK1A, BRMS1 |
| positive regulation of protein dephosphorylation | biological process | TGFB1, NSMF, GBA, PPP2R5A, CNEP1R1, PPP1R7, PIN1, CDCA2, DLC1, SMPD1, PPP2R5D, PINK1, CALM1, CALM2, CALM3, CAMTA1, ANKLE2, PPP1R16B, PRKCD, CDH5, SPPL3, SYMPK |
| positive regulation of protein depolymerization | biological process | SLN |
| positive regulation of protein deubiquitination | biological process | ZC3H12A, TANK, WDR48, TNIP1 |
| positive regulation of protein exit from endoplasmic reticulum | biological process | SAR1A, TMEM30B, SEC16A, CD81, SAR1B, TM9SF4, TMEM30A, SORL1, SLC51B, SLC35D3, SEC16B |
| positive regulation of protein export from nucleus | biological process | IL1B, TP53, GSK3B, MDM2, GAS6, TCF7L2, EMD, XPO4, RBM22, ANP32B, BAG3, YWHAE, SFN, CTDSPL2, TPR, PPM1A, GTSE1, RAPGEF3, CAMK1 |
| positive regulation of protein folding | biological process | POFUT2, GRN |
| positive regulation of protein glycosylation | biological process | ALG10B, CHP1, SLC51B, RAMP1, GOLGA2 |
| positive regulation of protein glycosylation in Golgi | biological process | ARFGEF1 |
| positive regulation of protein homodimerization activity | biological process | PARK7, ZNF268 |
| positive regulation of protein homooligomerization | biological process | FAS |
| positive regulation of protein import | biological process | ARHGEF5 |
| positive regulation of protein import into nucleus | biological process | TGFB1, LEP, SHH, MAPK14, GLI3, JAK2, UBR5, ZC3H12A, RBM22, PIK3R1, XBP1, DMAP1, CHP2, BAG3, IPO5, PSEN1, SMO, RAN, ZPR1, ECT2, PRKCD, EFCAB7, TPR, HDAC3, HCLS1, HYAL2, JUP, NUTF2, PIK3R2, SMAD3, MAVS |
| positive regulation of protein import into nucleus, translocation | biological process | IL6, BRCA1, CDK1, HSP90AA1, IGF1 |
| positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological process | TP53, BCL2, E2F1, CASP8, BAD, MAPK8, YWHAQ, TP63, DYNLL1, TFDP1, YWHAH, TP53BP2, GZMB, PPP3CC, YWHAZ, BID, YWHAE, SFN, NMT1, TFDP2, YWHAB, PPP1R13B, YWHAG, PPP3R1, BBC3 |
| positive regulation of protein insertion into mitochondrial outer membrane | biological process | PDCD5 |
| positive regulation of protein K48-linked ubiquitination | biological process | BIRC2 |
| positive regulation of protein K63-linked ubiquitination | biological process | DDX3X, NOD2, PTPN22, BIRC2 |
| positive regulation of protein kinase A signaling | biological process | MIF, IAPP, AKAP12, NRXN1, ADIPOQ, ADRB2, ADGRV1, RAMP3, CALCR, MC1R |
| positive regulation of protein kinase activity | biological process | TNF, GAS6, NRG1, RAP1A, CSF1, CCN1, CENPE, CACUL1, XRCC5, IQGAP1, ALS2, DUSP19, RAPGEF2, MAPRE3, PTK2, PRKAG2, ADIPOQ, SDC4, WNT3A, VLDLR, XRCC6, MAP2K3, MMD, CAMKK1, PTPRC, PSEN1, SNX9, EREG, RASSF2, CDK5R1, TAB2, SPDYA, JTB, VEGFC, AGAP2, TRAF4, CDKN1A, LCP2, CDK5R2, CCL19, PPP1R9A, CD4, CCR7, AZU1, CDK5, DAG1, LAT, EPO, MRNIP, MMD2, CDC25B, PTK2B, CCL21, RELN |
| positive regulation of protein kinase B signaling | biological process | EGFR, F10, TGFB1, TNF, IL6, IGF2, AXL, GAS6, GPX1, F3, LEP, AKR1C3, MTOR, PARK7, INSR, SRC, NRG1, C1QBP, TCF7L2, PTPRJ, IAPP, AREG, HPSE, STK3, ARFGEF1, RTN4, PIK3R1, PDGFB, TGFA, XBP1, CCL3, PTK2, RASD2, HAX1, BAG4, F7, AKR1C2, NRXN1, PIK3AP1, TSPYL5, NRG4, MYDGF, CHI3L1, MAZ, RHOG, FGF23, THBS1, GATA3, CD86, TEK, OSBPL8, IRS2, IRS1, GCNT2, P2RY12, FGF5, STOX1, MEIS3, PINK1, EREG, PDGFA, ANGPT1, ITGB1BP1, LRP2, FGF20, NRG2, GRB2, RAC1, GAB1, CPNE1, RAC2, C1QTNF1, TGFBR1, CX3CR1, FRS2, HBEGF, OSM, HCLS1, PIK3CG, CCL19, SPRY2, RAMP3, FGF18, CSF3, ERBB3, ILK, FGF22, RET, PDGFRB, FGF7, CCR7, BTC, MFHAS1, PIK3CD, FGF19, FGF6, VEGFB, MST1R, LCK, FGF2, CD28, PDGFRA, ENG, P2RX4, KL, PIK3R2, VAV1, FGFR4, IGFBP5, CALCR, ADAM8, INS, ARRB2, MYORG, PIK3R5, CD19, ITSN1, FGF1, TNFAIP8L3, CCL21, THPO, MC1R, SEMA5A, FAM110C, TRAT1, MYOC, FGF10, ESR1, CD80, LIN28A, IL26 |
| positive regulation of protein kinase C activity | biological process | CEMIP, NRXN1, DIPK2A, ROR2 |
| positive regulation of protein kinase C signaling | biological process | VEGFA, PLA2G6, SPHK2, FLT4, ADRA1A, ADGRV1, WNT11, CD40, MC1R |
| positive regulation of protein kinase D signaling | biological process | VEGFA |
| positive regulation of protein linear polyubiquitination | biological process | XIAP, PRKN |
| positive regulation of protein lipidation | biological process | RAB3GAP2, SVIP, RAB3GAP1 |
| positive regulation of protein localization to actin cortical patch | biological process | PPP1R9B |
| positive regulation of protein localization to basolateral plasma membrane | biological process | CACNG2 |
| positive regulation of protein localization to Cajal body | biological process | CCT5, CCT4, DKC1, CCT7, CCT2, TCP1, CCT6A, CCT3, CCT8, MEPCE |
| positive regulation of protein localization to cell cortex | biological process | GPSM2, NUMA1, EPB41, EPB41L2 |
| positive regulation of protein localization to cell surface | biological process | TNF, NRG1, STX3, ABCA12, RANGRF, SNX33, TM9SF4, TYROBP, CD247, GPD1L, FCER1G, LRIG2, STX4, ABCA7 |
| positive regulation of protein localization to cell-cell junction | biological process | PECAM1 |
| positive regulation of protein localization to centrosome | biological process | NUP62, BICD1, APC, PARD6A, CEP250, MARK4 |
| positive regulation of protein localization to chromosome, telomeric region | biological process | GNL3L, GNL3, PML |
| positive regulation of protein localization to ciliary membrane | biological process | EFCAB7 |
| positive regulation of protein localization to cilium | biological process | ENTR1, CCDC88A, GAS8, CROCC |
| positive regulation of protein localization to early endosome | biological process | VEGFA, EZR, DTX3L, ROCK2, MSN, RDX, SORL1, MGAT3 |
| positive regulation of protein localization to endoplasmic reticulum | biological process | RTN4, DDRGK1 |
| positive regulation of protein localization to endosome | biological process | ABHD17B, ABHD17A, ZDHHC1 |
| positive regulation of protein localization to kinetochore | biological process | TRAPPC12, NDC80, CENPQ |
| positive regulation of protein localization to lysosome | biological process | GPR137B, MEAK7 |
| positive regulation of protein localization to membrane | biological process | PRKN, AP2B1, NECAB2 |
| positive regulation of protein localization to nucleolus | biological process | TERT, MCRS1, PINX1 |
| positive regulation of protein localization to nucleus | biological process | TGFB1, LIF, CDK1, AKT1, CDKN2A, PARK7, KAT7, DTX3L, LAMTOR5, TFRC, CDK5RAP3, CARD10, TRIM8, PLK1, GTSE1, CD2AP, NGFR, SESN2, F2, INS, GLIS2, PYHIN1, EIF2AK3 |
| positive regulation of protein localization to plasma membrane | biological process | PRNP, KIF5B, RAB11FIP2, SORBS1, WNK3, RAB11A, ZDHHC8, PIK3R1, PPP1R9B, PRKCH, ZDHHC5, EPHB2, STX3, PLS1, NRXN1, RANGRF, SPTBN1, WNT3A, RHOG, AGR2, SQSTM1, PTPN9, DLG1, RER1, PRKCE, TREM2, RAMP3, ARF6, LRP1, EPHA2, STAC2, STX4, EPHA3, AKAP5, NKD2, STAC3, PDPK1, ITGA3, ARHGEF16, VIL1, CLIP3, TNF, GPER1 |
| positive regulation of protein localization to presynapse | biological process | DVL1, WNT7A |
| positive regulation of protein localization to spindle pole body | biological process | NUMA1 |
| positive regulation of protein localization to synapse | biological process | NLGN2, CLSTN3 |
| positive regulation of protein maturation | biological process | TFR2 |
| positive regulation of protein metabolic process | biological process | MAPK8, WFS1, KLF4, CHRNA7, MAPK7, MAP2K5, KLF2 |
| positive regulation of protein modification process | biological process | ATG10, NUPR1, ASPSCR1 |
| positive regulation of protein monoubiquitination | biological process | BIRC2, PDCD6, UBB, PEF1 |
| positive regulation of protein neddylation | biological process | DCUN1D1 |
| positive regulation of protein O-linked glycosylation | biological process | IL15, POMT1 |
| positive regulation of protein oligomerization | biological process | TP53, BAX, ZDHHC1 |
| positive regulation of protein oxidation | biological process | TRABD2B, TRABD2A |
| positive regulation of protein phosphorylation | biological process | EGFR, TGFB1, TNF, IL1B, IL4, MMP9, VEGFA, SOX9, IGF2, ERBB2, MAPK3, AKT1, KDR, GAS6, CIB1, SEMA7A, C3, EDNRA, MTOR, HSPA2, PLAUR, INSR, BMP4, MIF, IL2, RAF1, CDC42, PLA2G6, NTRK1, ANXA2, AIF1, CCN1, CCN2, SENP2, RB1CC1, CD74, FXR1, NPTN, STK4, PIN1, MOB2, FZD8, AKTIP, XBP1, RACK1, NKX3-1, DVL1, KRAS, EFNA1, PTK2, IQGAP3, ROCK2, TFRC, FLT4, DAB2, GPNMB, MYDGF, RASGRP1, ZNF268, ADIPOQ, IL34, CCND1, WNT3A, SEMA4D, CRH, TEK, NTRK2, NIBAN1, PELI2, MARCO, MAP2K4, CSNK1D, EFNA5, ODAM, AXIN1, CHRNA7, PSEN1, UCN, SQSTM1, CDON, PINK1, EDNRB, ANGPT1, PRR5L, ADTRP, FLOT1, ITGB3, RALB, FXR2, HIPK2, RAC1, FAM20A, TNIK, CDK2AP1, DVL2, ABL1, PIK3R3, FIZ1, MAP3K5, LYN, VEGFC, FBH1, FNIP1, IRGM, FLCN, HDAC3, ACVR2A, MAP2K6, P2RX7, TREM2, LIMCH1, MT3, P2RY1, ILK, KNDC1, ITLN1, CD4, FPR2, EPHA7, DVL3, FAXDC2, AXIN2, PDE8A, FGF19, HRAS, RAP2A, BMP2, VEGFB, PRR5, CDK5, BRAT1, WDFY2, PECAM1, ENG, RARRES2, CAMKK2, F2, CSF1R, AKT2, ARRB2, PROM2, CD40, CARD14, FZD1, FGF1, CCND3, SLCO3A1, THPO, CRKL, FLT3LG, LRRK2, MAVS, CLIP3, AGER, G |
| positive regulation of protein polymerization | biological process | TPPP3, TPPP2, TPPP, TTBK1 |
| positive regulation of protein polyubiquitination | biological process | MARCHF7, FBXO4, BIRC2, SKP2, RNF40, UBE2D1, HAMP, SPSB4 |
| positive regulation of protein processing | biological process | CCBE1, ANGPTL8, CNTN2, SPON1, MMP14, RHBDD1, TIMM17A, ADAM8, NKD2, ASTL |
| positive regulation of protein processing in phagocytic vesicle | biological process | MYH9 |
| positive regulation of protein secretion | biological process | TGFB1, TGFB3, IL1A, IGF1, EZR, DNM1L, MYH10, EXPH5, KCNN4, SYTL4, FGG, IL13, ATP13A2, ABCG1, ARF1, PPID, TTN, FGB, MYO18A, TGFB2, GOLPH3L, GOLPH3, UNC13B, ADAM9, FRMD4A, VEGFC, PARD6A, EXOC1, PLA2G1B, CD2AP, BMP6, P2RX7, TREM2, ARF6, CD33, FGA, ANG, ADAM8, APBB1, ADORA2A, MYOM1, RPH3AL, SEC24A, PPIA, ANKRD1 |
| positive regulation of protein serine/threonine kinase activity | biological process | IGF2, EZH2, CIB1, LTF, SRC, CAB39, DDX3X, STK3, PDCD10, DBF4, HIGD1A, PPP2CA, ALS2, STK4, SNCA, DAB2IP, ACSL1, ADRB2, SLC27A1, HMGA2, DAZAP2, PARP16, CALM1, CALM2, CALM3, RALB, MAP2K2, CDK5R1, SYAP1, STRADA, FAM20A, CAB39L, PARP6, IRGM, MTCP1, TCL1A, DBF4B, ETAA1, SPRY2, MAP2K1, PARP8, MLST8, TCL1B, CSF1R, RPTOR, CAMK1, SLC8A2, INCENP, DELE1 |
| positive regulation of protein sumoylation | biological process | CDKN2A, HDAC4, PIAS1, GNL3, RASD2, UBA2, RWDD3, TOLLIP, MUL1, PIAS3, PIAS4, SAE1 |
| positive regulation of protein targeting to membrane | biological process | ERBB2, CIB1, PRNP, ANK3, MFF, C2CD5, CEMIP, STOM, ITGAM, HPCA, TCAF2, ITGB1BP1, KCNB1, CDK5R1, MIEF2, MIEF1, FIS1, CHP1, TCAF1, ITGB2, HRAS, CDK5, MYO1C, SLC51B, MTCL1, CACNB3, AKT2 |
| positive regulation of protein targeting to mitochondrion | biological process | CSNK2A2, NRG1, HSPA1L, UBE2D3, SREBF2, RHOU, HUWE1, FBXW7, SH3GLB1, ARIH2, NPEPPS, HTRA2, HPS4, PINK1, UBL4B, TOMM7, LEPROT, UBE2L3, USP36, RAC2, UBE2J2, UBL5, FZD5, RNF31, MICALL2, BAP1, ABLIM3, SAE1, ATG13 |
| positive regulation of protein transport | biological process | TNF, SRC, CREBRF, PRKCZ, CHP1, LRP1 |
| positive regulation of protein tyrosine kinase activity | biological process | ACE, GAS6, GHRL, CCL5, NRG1, PRNP, LILRA5, PDGFB, EFNA1, ERCC6, IL34, WNT3A, AFAP1L2, UNC119, NEDD9, DVL2, ALKAL2, ABI1, PTPN1, EPHA4, DLG4, GPRC5B, ERBB3, ALKAL1, DLG3, CSF1R, DOK7, SRCIN1, AGT, GRM5, NCAPG2, RELN, GREM1 |
| positive regulation of protein tyrosine phosphatase activity | biological process | SLC39A10, PTPRC, CD33 |
| positive regulation of protein ubiquitination | biological process | BRCA1, HSPA5, WFS1, RASSF1, 38231, MALT1, UBE3A, SENP2, XIAP, BCL10, PTTG1IP, AIMP2, HUWE1, FBXW7, PELI1, DERL1, PSMD10, CHFR, TSPYL5, CDK5RAP3, BIRC7, PHF23, FBXO4, STUB1, ADRB2, RASSF5, AXIN1, PINK1, BIRC2, ANGPT1, UBE2L3, COMMD1, MAPK9, CENPX, RIPK2, RNF111, NSMCE3, RCHY1, NDFIP1, NDFIP2, TRAF6, MYCBP2, CRY1, UBE2D1, HDAC3, AVPR2, AMER1, INAVA, SPRTN, KLHL40, UBB, DNAJB2, CENPS, PRICKLE1, TBC1D7, ARRB2, FAM107A, PAXIP1, LRRK2, CAV1, TICAM1 |
| positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological process | EGF, CLU, PTEN, AGBL4, FBXW7, PTK2, CDK5RAP3, DISC1, CAV3, AXIN1, FBXO22, RNF139, MAGEF1, CCDC22, TRIM67, PTK2B, PYHIN1 |
| positive regulation of proteoglycan biosynthetic process | biological process | SLC2A10 |
| positive regulation of proteolysis | biological process | BAK1, CASP8, BAD, OGT, HDAC2, BTRC, CAPN3, STUB1, IST1, TRIM32, FADD, CYFIP2, PLK1, AURKAIP1, ASPH, PERP, FGFR4, CLN6 |
| positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GBA, RGN, CTSC, ATP5IF1 |
| positive regulation of proton-transporting ATP synthase activity, rotational mechanism | biological process | ATPSCKMT |
| positive regulation of pseudopodium assembly | biological process | KIT, CDC42, CDC42EP5, CDC42EP2, CDC42EP3, CDC42EP4, APC, CDC42EP1, CCR7, CCL21 |
| positive regulation of pyrroline-5-carboxylate reductase activity | biological process | PARK7 |
| positive regulation of pyruvate dehydrogenase activity | biological process | PPM1J, PDP1, PDP2, PPM1H |
| positive regulation of Rac protein signal transduction | biological process | ALS2, RTN4, AUTS2, KRAS |
| positive regulation of Ras protein signal transduction | biological process | KITLG, IGF1, NRG1, NTRK1, CSF1, JAK2, SHC1, SHOC2, RASGRP1, ITPKB, NOTCH1, RASGRP4, DGKI, IRS2, RAPGEF1, EPOR, GRB2, LYN, RASGEF1A, HRAS, VAV1, EPO, MMD2, RASGRF1, CRKL, FGF10 |
| positive regulation of reactive oxygen species biosynthetic process | biological process | PARK7, HDAC4, RAB27A, GRIN1, CYBA, ADGRB1, FOXO3, TLR6, MMP8, CD36 |
| positive regulation of reactive oxygen species metabolic process | biological process | TP53, NFE2L2, LEP, AKR1C3, XDH, PLAU, MAPK14, NOX5, ACE2, ZC3H12A, PDGFB, RNF41, THBS1, AGTR1, PID1, GADD45A, GRB2, CDKN1A, RIPK3, PDGFRB, TGFBR2, DUOXA1, NQO2, F2, AGT, PTK2B, CD36 |
| positive regulation of receptor activity | biological process | IGF2, HFE, NCOA2, ANXA2, NCAPG2, GREM1 |
| positive regulation of receptor binding | biological process | MMP9, B2M, HFE, HOXA3, PLCL1, PLCL2 |
| positive regulation of receptor biosynthetic process | biological process | HIF1A, NR1H3, JAK2, HDAC2, HOXA5, CDK5R1, HDAC6, EDN1 |
| positive regulation of receptor catabolic process | biological process | ITCH, DTX3L, PTPN1, HAMP |
| positive regulation of receptor clustering | biological process | TGFB1, env, CD81 |
| positive regulation of receptor internalization | biological process | VEGFA, FMR1, GH1, PICK1, AHI1, SYK, WNT3A, CD63, ANGPT1, SCYL2, HAMP, TBC1D5, NTF3, SFRP4, DRD2, ARRB2, PCSK9, PLCG2, MAGI2, ATAD1, GREM1 |
| positive regulation of receptor localization to synapse | biological process | STX7, TYROBP, ZDHHC3 |
| positive regulation of receptor recycling | biological process | RAB29, ARAP1, SNCA, ECE1, NSF, BVES, INPP5F, EPS15, SCRIB, PSEN1, VAMP3, RAMP3, NSG1 |
| positive regulation of receptor signaling pathway via STAT | biological process | TSLP, CRLF2, IL7R |
| positive regulation of receptor-mediated endocytosis | biological process | SERPINE1, TF, B2M, HFE, RAB21, PPT1, BICD1, CBL, APOA5, CCL19, VTN, H1-1, HNRNPK, AP2A1, HIP1R, CCL21, SGIP1 |
| positive regulation of reciprocal meiotic recombination | biological process | UBE2B, PRDM9, PRDM7 |
| positive regulation of regulated secretory pathway | biological process | RAB27A, RAB15, UNC13D, RAB3D |
| positive regulation of regulation of vascular smooth muscle cell membrane depolarization | biological process | TRPM4 |
| positive regulation of regulatory T cell differentiation | biological process | TGFB1, CD46, HLA-G, IL2, BCL6, SOX12, SOCS1, LILRB4, VSIR, DUSP10 |
| positive regulation of relaxation of cardiac muscle | biological process | HRC |
| positive regulation of release of cytochrome c from mitochondria | biological process | TP53, MMP9, TNFSF10, BAX, BAK1, PLAUR, BAD, DNM1L, PLA2G6, MFF, PDCD5, BCL2L11, MLLT11, WDR35, HRK, BID, PINK1, PPIF, BNIP3, FAM162A, BMF, MOAP1, PYCARD, BIK, CIDEB, BBC3, GPER1 |
| positive regulation of release of sequestered calcium ion into cytosol | biological process | BAX, EDNRA, F2R, TEX101, SRI, F2RL3, CXCL11, SNCA, CEMIP, CAPN3, IL13, ABL1, TRPC1, CXCR3, DRD1, APLNR, THY1, PDPK1, F2, NTSR1, CD19, CASQ1, BDKRB1, CXCL10, AKAP6, GPER1 |
| positive regulation of renal albumin absorption | biological process | ADIPOQ |
| positive regulation of renal sodium excretion | biological process | OXT, TAC1, GNAI2, SNX5, EDNRB, NPR1, DRD3, EDN1, DRD2, ADORA2A, AGT |
| positive regulation of renal water transport | biological process | INPP5K |
| positive regulation of respiratory burst | biological process | INSR, CAMK1D, INS |
| positive regulation of respiratory burst involved in inflammatory response | biological process | RPS19, LBP |
| positive regulation of response to cytokine stimulus | biological process | IFIH1, TAF9, MAVS |
| positive regulation of response to DNA damage stimulus | biological process | FMR1, MYC, ANKLE1, BCLAF1, FXR1, NKX3-1, NSMCE4A, HMGA2, FXR2, PRKCD, NSMCE1, PAXIP1 |
| positive regulation of response to endoplasmic reticulum stress | biological process | FCGR2B |
| positive regulation of response to food | biological process | GHRL |
| positive regulation of response to oxidative stress | biological process | SELENON, MACROH2A1, ACOX2 |
| positive regulation of response to wounding | biological process | ATP7A |
| positive regulation of retinal ganglion cell axon guidance | biological process | VEGFA, NRP1 |
| positive regulation of retinoic acid biosynthetic process | biological process | RDH10 |
| positive regulation of retinoic acid receptor signaling pathway | biological process | ASXL1, CTBP2, NR2C1, TRIM16, KLF2 |
| positive regulation of retrograde protein transport, ER to cytosol | biological process | EDEM2, BCAP31, EDEM1 |
| positive regulation of retrograde transport, endosome to Golgi | biological process | PRKN, EIPR1 |
| positive regulation of Rho guanyl-nucleotide exchange factor activity | biological process | EPHA4 |
| positive regulation of Rho protein signal transduction | biological process | F2R, LPAR4, F2RL3, ARHGEF3, ABRA, RTN4R, COL3A1, LPAR6, GPR4, APOA1, RAC1, F11R, AKAP13, LPAR1, MCF2L, F2RL2, PDGFRB, GPR55, GPR17, PRAG1, GPR20, GPR35, NET1, GPR65, ROBO1 |
| positive regulation of rhodopsin gene expression | biological process | NR2E3, MFSD2A, NRL |
| positive regulation of ribosomal small subunit export from nucleus | biological process | RIOK2 |
| positive regulation of RIG-I signaling pathway | biological process | PUM2, PUM1, ZC3HAV1, TRIM15, ZCCHC3, DHX58, ANKRD17, USP15, DDX60 |
| positive regulation of RNA binding | biological process | NCBP1 |
| positive regulation of RNA export from nucleus | biological process | KHDRBS1, NCBP2, NRDE2, RBM26, CPSF6 |
| positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological process | LAMTOR5, EP300, IL32, DDRGK1 |
| positive regulation of RNA polymerase II transcription preinitiation complex assembly | biological process | PSMC2, PSMC6, PSMC5, PSMC3, PSMC4, CAND1, WNT10B, ESR1, TP53 |
| positive regulation of RNA splicing | biological process | DYRK1A, RBM22, PIK3R1, SETX, SLC38A2, ZPR1, ERN1, HNRNPLL, HABP4, U2AF2, POLR2A, RBM20, SRSF5, HSPA1A |
| positive regulation of rRNA processing | biological process | WDR75, DIMT1, RIOK1, HEATR1, BUD23, SIRT7, RIOK2 |
| positive regulation of ruffle assembly | biological process | COBL, FAM98A, P2RY12, EPS8, CYFIP1, DEF8, HRAS, CARMIL2, EPS8L1 |
| positive regulation of ryanodine-sensitive calcium-release channel activity | biological process | TRDN, GSTO1, CALM1, CALM2, CALM3, JPH2, ASPH, AKAP6 |
| positive regulation of saliva secretion | biological process | TAC1, AQP1 |
| positive regulation of sarcomere organization | biological process | EDN1, PROX1, MYLK3 |
| positive regulation of satellite cell activation involved in skeletal muscle regeneration | biological process | CAPN3, SOX15 |
| positive regulation of Schwann cell chemotaxis | biological process | TIAM1 |
| positive regulation of Schwann cell differentiation | biological process | DICER1, RELA, EGR2 |
| positive regulation of Schwann cell migration | biological process | LRP1 |
| positive regulation of sclerotome development | biological process | SHH |
| positive regulation of secondary heart field cardioblast proliferation | biological process | TBX5, SIX1, EYA1 |
| positive regulation of secretion | biological process | SCIN, ACSL3, GPLD1, RHBDD1 |
| positive regulation of secretion of lysosomal enzymes | biological process | NR1H2 |
| positive regulation of selenocysteine incorporation | biological process | RPL30 |
| positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis | biological process | HAND2 |
| positive regulation of sensory perception of pain | biological process | MTOR, ATPSCKMT, NMU, TAC4, CCK, PTAFR, OPRL1, P2RX3 |
| positive regulation of sequence-specific DNA binding transcription factor activity | biological process | TNF, IL1B, ESR1, IL4, IL6, IL10, ESR2, AKT1, NODAL, CTNNB1, PTEN, PARK7, IL5, KIT, PPARG, HDAC4, TFDP1, COPS5, JAK2, DDIT3, GTF2A2, CEBPG, NDP, STK3, TAF12, TRIM4, NKX2-2, ZIC2, SMARCA4, TRIM25, ABRA, NEUROG2, BEX1, FZD4, TRIM37, NKX3-1, ANXA3, JMY, RNF41, FOXA1, TRIM15, PPARGC1A, ARHGEF5, FZD2, ARID5B, NEUROG1, WNT3A, CYTL1, TRIM32, PHB2, TRIM8, LRP6, SMARCB1, PINK1, NHLH2, NEUROD1, SP100, EP300, HIPK2, SAV1, TRIM38, PPP3CA, RNF187, DVL2, MBTPS2, TRAF6, ATF2, TP53BP1, MYOCD, RGCC, HCLS1, STING1, TRIM62, LRP5, CSF3, TRIM52, MID2, TRAF5, SRF, NFAM1, PRKD2, PYCARD, TNFRSF11A, WNT10B, PLPP3, EDN1, JUP, TRIM21, TRIM14, PPRC1, TRIM41, PPARGC1B, HDAC5, TRAF2, FZD1, SMAD3, MAVS, FANK1, TRIM5, TRIM22, TRIM31 |
| positive regulation of sequestering of calcium ion | biological process | RYR2, FKBP1B |
| positive regulation of sequestering of triglyceride | biological process | CIDEA, FITM1, PLIN2, LPL, OSBPL11, PLIN3 |
| positive regulation of sequestering of zinc ion | biological process | SLC30A2 |
| positive regulation of serine C-palmitoyltransferase activity | biological process | SERINC1, SERINC5, SERINC2 |
| positive regulation of serine-type endopeptidase activity | biological process | SEMG1, SEMG2 |
| positive regulation of serotonin secretion | biological process | SLC6A4 |
| positive regulation of signal transduction | biological process | KHDRBS1, ADAMTS20, PTPN11, EIF2A, ADIPOQ, GATA3, HOMER1, ILK, CDKN2AIP, CD80 |
| positive regulation of signal transduction by p53 class mediator | biological process | CDKN2A, RPL11, CDK5RAP3, CHD5, RPL23, HEXIM1 |
| positive regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | TOP2A, TOP2B |
| positive regulation of single-stranded telomeric DNA binding | biological process | ACD |
| positive regulation of sister chromatid cohesion | biological process | FEN1, SFPQ, RAD21, DDX11 |
| positive regulation of skeletal muscle acetylcholine-gated channel clustering | biological process | PTN, MESD, LRP4 |
| positive regulation of skeletal muscle cell differentiation | biological process | MEF2C, ARNTL, GPC1 |
| positive regulation of skeletal muscle cell proliferation | biological process | SHH |
| positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion | biological process | GSTO1 |
| positive regulation of skeletal muscle fiber development | biological process | BCL2, MYOD1, MYOG, NIBAN2 |
| positive regulation of skeletal muscle fiber differentiation | biological process | RBM24 |
| positive regulation of skeletal muscle hypertrophy | biological process | MTOR, MYMK |
| positive regulation of skeletal muscle tissue development | biological process | CTNNB1, SHH, HMGCR, WNT3A, MEF2C, CDON, FLOT1 |
| positive regulation of skeletal muscle tissue growth | biological process | NACA, MTM1, ACTN3, DLL1 |
| positive regulation of skeletal muscle tissue regeneration | biological process | PPARD, TGFBR2, MYOD1 |
| positive regulation of SMAD protein import into nucleus | biological process | TGFB1, TGFB3, NODAL, PARP1, BMP4, NUP93, JAK2, SMAD4, BMPR1A, DAB2, KIAA0319, TGFBR1, BMP6, RBPMS |
| positive regulation of small GTPase mediated signal transduction | biological process | SOS1, FRMD7, CDON, SOS2, ADCYAP1R1, RELN |
| positive regulation of small intestinal transit | biological process | GHSR |
| positive regulation of small intestine smooth muscle contraction | biological process | GHSR |
| positive regulation of smooth muscle cell apoptotic process | biological process | IFNG, IL12A, CDKN2A, RBM10, PDCD4, MAP2K4 |
| positive regulation of smooth muscle cell chemotaxis | biological process | AIF1, PDGFD, MDK, LPAR1 |
| positive regulation of smooth muscle cell differentiation | biological process | TGFB1, PIAS1, SMARCD3, MYOCD, OLFM2 |
| positive regulation of smooth muscle cell migration | biological process | BCL2, F3, IGF1, SRC, CCL5, PLAU, HDAC4, SEMA6D, PDGFB, HAS2, POSTN, ITGA2, VTN, PDGFRB, FOXO4, CRK, NRP1, P2RY6, CCN4 |
| positive regulation of smooth muscle cell proliferation | biological process | TNF, IL6, IL6R, PTGS2, HIF1A, HMOX1, FLT1, FGFR2, STAT1, GSK3B, MTOR, IGF1, BMP4, CCL5, ELANE, AIF1, CX3CL1, AKR1B1, HDAC4, NOX1, PDGFB, IRAK1, CALCRL, PDGFD, PPARGC1A, IL13, HMGCR, S1PR1, FOXP1, THBS1, SERPINF2, CYBA, NAMPT, ITGA2, SMPD3, EREG, SKP2, TRAF6, HBEGF, TGM2, NOTCH3, ID2, PDGFRB, TGFBR2, CDH13, EDN1, MNAT1, PTAFR, NR4A3, ABCC4, CCN4, RBPMS2, IRAK4, NPY5R |
| positive regulation of smooth muscle contraction | biological process | PTGS1, PTGS2, F2R, PROK2, CTTN, NMU, ITGA2, CHRM3, ADRA1A, ADA, MYOCD, SRF, EDN1, PTAFR, TBXA2R |
| positive regulation of smoothened signaling pathway | biological process | SHH, FGF9, DYNC2H1, TXNDC15, STK36, CTNNA1, PDCL, CHSY1, DLG5, INTU, FOXA1, POR, DCDC2, FAM92A, PRRX1, ULK3, SMO, NDST1, TEDC1, GLI1, TTC23, SCUBE1, GAS8, TEDC2, UCHL5, ARMC9, RAB34, GPC3, EVC, IHH, KIF7, WNT9A, IFT172 |
| positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GORAB |
| positive regulation of SNARE complex assembly | biological process | SNCA, CLTRN |
| positive regulation of snRNA transcription by RNA polymerase II | biological process | MEPCE, ZNF143, MYOD1 |
| positive regulation of sodium ion export across plasma membrane | biological process | FXYD1, ATP1B1, ATP1B2, ATP1B3 |
| positive regulation of sodium ion transmembrane transport | biological process | ARF1 |
| positive regulation of sodium ion transmembrane transporter activity | biological process | WNK3, ANK3, DMD, WNK4, WNK1, WNK2, CNKSR3, GLRX |
| positive regulation of sodium ion transport | biological process | AKT1, FGF12, WNK3, ANK3, AHCYL1, CNTN1, SCN1B, GPD1L, MLLT6, CNKSR3, PKP2, NKX2-5, SCN4B, SCN5A, SCN3B |
| positive regulation of sodium-dependent phosphate transport | biological process | ATF4, SLC34A1 |
| positive regulation of sodium:proton antiporter activity | biological process | CHP1, TESC, ACTN4, DRD4 |
| positive regulation of somatic stem cell division | biological process | LBH |
| positive regulation of somatic stem cell population maintenance | biological process | LBH |
| positive regulation of somatostatin secretion | biological process | SCT |
| positive regulation of spermidine biosynthetic process | biological process | PAOX |
| positive regulation of sphingolipid mediated signaling pathway | biological process | KLF14 |
| positive regulation of sphingomyelin catabolic process | biological process | PRKCD, ENPP7 |
| positive regulation of spindle assembly | biological process | GPSM2, NUMA1, MAPK15 |
| positive regulation of spontaneous neurotransmitter secretion | biological process | STX1B |
| positive regulation of sprouting angiogenesis | biological process | ITGA5, KLF4, TJP1, JCAD, PKM, GHSR, JAK1, DLL1, FGF2, BMPER, PDPK1, JMJD8, FGF1, S100A1 |
| positive regulation of SREBP signaling pathway | biological process | C12orf49, ZBTB7B |
| positive regulation of STAT protein import into nucleus | biological process | IL6, LEP |
| positive regulation of stem cell differentiation | biological process | GSK3B, PWP1, NUDT21, PTN, TACSTD2, HOXB4, RBM24, SP7 |
| positive regulation of stem cell population maintenance | biological process | NCOA3, ZNF322, REST, YAP1, ESRRB |
| positive regulation of stem cell proliferation | biological process | TERT, HNRNPU, EPCAM, HMGA2, PTPRC, SOX11, TBX3, SIRT6 |
| positive regulation of steroid hormone biosynthetic process | biological process | CYP17A1, POR |
| positive regulation of steroid metabolic process | biological process | SCP2 |
| positive regulation of sterol regulatory element binding protein cleavage | biological process | LPCAT3 |
| positive regulation of stomach fundus smooth muscle contraction | biological process | NMU |
| positive regulation of store-operated calcium channel activity | biological process | BMP4, CASQ1 |
| positive regulation of stress fiber assembly | biological process | MTOR, KISS1R, TPM1, NF2, TAC1, CCN2, ARHGEF10, PXN, CD47, ROCK2, BAG4, PFN2, TSC1, WNT4, ARHGEF5, CCDC88A, SDC4, AMOT, SERPINF2, ITGB1BP1, SORBS3, APOA1, RAC1, ARHGEF10L, EVL, ABL1, TGFBR1, CARMIL1, RGCC, EPHA1, LPAR1, LIMCH1, WNT11, RAPGEF3, PPM1E, S100A10, NRP1, RHOC, SH3PXD2B, LIMK1, FHOD1, SMAD3, GPR65, MYOC |
| positive regulation of stress granule assembly | biological process | G3BP1, G3BP2 |
| positive regulation of stress-activated MAPK cascade | biological process | IL1B, TLR4, ARL6IP5, PDCD10, STK25, SEMA4C, TAOK2, HMGCR, NOD2, TAOK3, TGFB2, RIPK2, KLHDC10, TAOK1, EIF2AK2, CARD9, MID1, INAVA, NOD1, MAPK8IP2, IL26 |
| positive regulation of stress-activated protein kinase signaling cascade | biological process | RNF13, LYN |
| positive regulation of striated muscle cell differentiation | biological process | NRG1, SHH, MORF4L2, TRIM32, NEK5, MESP1 |
| positive regulation of striated muscle contraction | biological process | ATP1A1 |
| positive regulation of striated muscle tissue development | biological process | GJA1, MRTFB |
| positive regulation of substrate adhesion-dependent cell spreading | biological process | CIB1, C1QBP, CDC42, ARHGEF7, P4HB, FGG, MDK, HAS2, FGB, NEDD9, DOCK5, APOA1, RAC1, ABL1, OLFM4, DOCK1, CARMIL1, MYADM, RREB1, TRIOBP, RAC3, UNC13D, PREX1, FGA, DMTN, CRK, S100A10, NRP1, CSPG5, LIMS2, CALR, CRKL, MYOC |
| positive regulation of substrate-dependent cell migration, cell attachment to substrate | biological process | FN1, STK4, FBLN1 |
| positive regulation of subtelomeric heterochromatin assembly | biological process | SIRT6 |
| positive regulation of succinate dehydrogenase activity | biological process | FXN, FTMT |
| positive regulation of SUMO transferase activity | biological process | UBE2I |
| positive regulation of superoxide anion generation | biological process | SOD1, TGFB1, CRP, GSTP1, GNAI2, GNAI3, SYK, ITGAM, CYBA, TYROBP, PRKCD, ITGB2, FPR2, AGT |
| positive regulation of superoxide dismutase activity | biological process | TNF, PARK7, RGN |
| positive regulation of supramolecular fiber organization | biological process | GPX1 |
| positive regulation of synapse assembly | biological process | BDNF, GHRL, OXTR, FLRT3, OXT, NTRK1, LRTM1, EEF2K, ASIC2, ADGRL1, FLRT1, DLG5, LRRN3, EPHB2, NRXN1, LRRTM1, NLGN2, ADNP, SRPX2, IL1RAP, FLRT2, NTRK2, SLITRK4, SLITRK5, EFNA5, EPHB1, LRRC4B, LINGO2, SLITRK1, CUX2, ADGRB3, SLITRK6, AMIGO3, ADGRB2, BHLHB9, CBLN2, ADGRB1, GRID2, SLITRK3, CLSTN1, AMIGO2, TPBG, SYNDIG1, SLITRK2, LRRTM2, EPHB3, AMIGO1, THBS2, LRRC24, CLSTN3, WNT7A, PTPRD, ADGRL3, LRTM2, LRRN1 |
| positive regulation of synapse maturation | biological process | CDC20, CAMK2B, ADGRL1, DAB2IP, NEURL1, ANAPC2, RELN |
| positive regulation of synapse structural plasticity | biological process | CDC42, CAMK1, FRMPD4 |
| positive regulation of synaptic growth at neuromuscular junction | biological process | AGRN |
| positive regulation of synaptic plasticity | biological process | PTGS2, CDC20, EPHB2, ADCY8, SSH1, ANAPC2, UNC13A, CPLX2 |
| positive regulation of synaptic transmission | biological process | KISS1R, OXT, KISS1, RIMS2, LGI1, RIMS1, KCTD13, SYT1, SLC1A3, NMU, PRKCZ, S100B, DLG4, CLSTN1, RIMS3, CLSTN3, GRIK2, RIMS4, TNF |
| positive regulation of synaptic transmission, cholinergic | biological process | IFNG, TAC1 |
| positive regulation of synaptic transmission, dopaminergic | biological process | PINK1, FLOT1, CHRNB2, ARRB2 |
| positive regulation of synaptic transmission, GABAergic | biological process | OXTR, CA2, TAC1, KIF5B, NLGN2, ADRA1A, ZDHHC3, PRKCE, CA7, ADORA2A, HAP1 |
| positive regulation of synaptic transmission, glutamatergic | biological process | PTGS2, OXTR, NTRK1, NRXN1, NLGN2, SHANK2, GLUL, TSHZ3, DRD1, ROR2, SHANK1, ADORA2A, PTK2B, RELN, CCL2 |
| positive regulation of synaptic vesicle clustering | biological process | NLGN2, MAGI2 |
| positive regulation of synaptic vesicle endocytosis | biological process | PPP3CC, DNM1, SH3GL1, LRRK2 |
| positive regulation of synaptic vesicle exocytosis | biological process | SLC4A8 |
| positive regulation of synaptic vesicle priming | biological process | UNC13B |
| positive regulation of synaptic vesicle recycling | biological process | DNM3, PLAA, DNM1 |
| positive regulation of syncytium formation by plasma membrane fusion | biological process | RAPGEF3, CAMK1, GCM1 |
| positive regulation of synoviocyte proliferation | biological process | TNF |
| positive regulation of systemic arterial blood pressure | biological process | NMU, ADRA1A, AVPR2, AVP, ENG |
| positive regulation of T cell activation | biological process | HLA-DPB1, HSPD1, SIRPG, MALT1, SIRPB1, CCDC88B, BCL10, CD47, PRKCQ, CD3E, HLA-DPA1, ADA, CD4, PYCARD, THY1, LCK, CORO1A, CARD11, CCL2 |
| positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological process | LGALS9, CD81, HLA-DMB |
| positive regulation of T cell anergy | biological process | CD3E |
| positive regulation of T cell apoptotic process | biological process | CCL5, PDCD1, PRELID1, IDO1, LGALS14, LGALS13 |
| positive regulation of T cell chemotaxis | biological process | CCL5, WNK1, S100A7, TMEM102, TNFSF14, OXSR1, CCL21, CCL27 |
| positive regulation of T cell costimulation | biological process | CCR7 |
| positive regulation of T cell cytokine production | biological process | B2M, MALT1, MAP3K7, TRAF6, TNFSF4, FZD5, TRAF2 |
| positive regulation of T cell differentiation | biological process | IL4, RAG1, IL12A, BAD, IL2RA, IL2, CD74, IL7, XBP1, ZMIZ1, MDK, GATA3, ZAP70, PTPRC, CYLD, ADA, RHOH, IL1RL2, PIK3R6, ZBTB1 |
| positive regulation of T cell differentiation in thymus | biological process | SHH, TESPA1, RASGRP1, EGR3, IL7R, ADA, VNN1, ADAM8, GLI2, IHH |
| positive regulation of T cell extravasation | biological process | CD99L2 |
| positive regulation of T cell mediated cytotoxicity | biological process | IL12A, IL23A, HLA-E, HLA-A, B2M, CD1C, IL12RB1, FADD, IL23R, STX7, PTPRC, P2RX7, CD1E, HLA-F |
| positive regulation of T cell mediated cytotoxicity directed against tumor cell target | biological process | MR1, SLC22A13 |
| positive regulation of T cell mediated immune response to tumor cell | biological process | HSPD1, FBXO38 |
| positive regulation of T cell mediated immunity | biological process | IL1B, PTPRC, ZBTB1 |
| positive regulation of T cell migration | biological process | CCL5, ITGA4, AIF1, CCL20, DOCK8, TNFRSF14, TMEM102, PYCARD, SPN, ADAM8, CXCL12, CCL21, CXCL10 |
| positive regulation of T cell proliferation | biological process | IFNG, IL1B, HLA-DPB1, IL4, IL6, IL12A, IL6ST, IL23A, LEP, IL2RA, CCL5, CD46, IL2, IL21, AIF1, IL15, CCDC88B, VCAM1, NCK1, HES1, TFRC, ANXA1, PNP, HAVCR2, NCK2, CD274, HLA-DMB, CD86, PRKCQ, CD209, IL23R, PTPRC, CD3E, TNFSF13B, HLA-DPA1, TRAF6, SLC7A1, PDCD1LG2, TNFSF4, CCL19, EFNB1, CD4, NCKAP1L, VTCN1, TNFRSF13C, CD28, CD6, CORO1A, JAK3, CARD11, ZP3, CD80 |
| positive regulation of T cell receptor signaling pathway | biological process | TESPA1, RAB29, CD81, RPS3, CD226, KCNN4, RELA, CYLD, ADA, CCR7, PRKD2, LCK, CARD11, TRAT1 |
| positive regulation of T cell tolerance induction | biological process | HLA-G, IDO1, TGFBR2 |
| positive regulation of t-circle formation | biological process | ERCC1, SLX1A, SLX4 |
| positive regulation of T-helper 1 cell cytokine production | biological process | IL1R1 |
| positive regulation of T-helper 1 cell differentiation | biological process | SOCS5, ANXA1, RIPK2, CCL19, HLX, CD80 |
| positive regulation of T-helper 1 type immune response | biological process | IL23A, IL12RB1, IL23R, RIPK2, PLA2G4A, SLC11A1, IL27RA |
| positive regulation of T-helper 17 cell differentiation | biological process | NFKBIZ, NLRP3 |
| positive regulation of T-helper 17 cell lineage commitment | biological process | IL23A, IL12RB1, IL23R |
| positive regulation of T-helper 17 type immune response | biological process | IL23A, IL12RB1, PRKCQ, IL23R |
| positive regulation of T-helper 2 cell activation | biological process | PRKCQ |
| positive regulation of T-helper 2 cell cytokine production | biological process | CD81, RSAD2, GATA3, NLRP3, PRKCZ |
| positive regulation of T-helper 2 cell differentiation | biological process | IL6, CD86, NLRP3, PRKCZ, TNFSF4, IL4R, RARA |
| positive regulation of tau-protein kinase activity | biological process | CLU, EGR1, DKK1, NAB2 |
| positive regulation of telomerase activity | biological process | MAPK3, MAPK1, CTNNB1, CCT4, KLF4, DKC1, PTGES3, PARM1, MAP3K4, XRCC5, PARN, CCT2, TCP1, TNKS, MAPKAPK5, POT1, WRAP53, PRKCQ, MAP2K7, PKIB, ACD, HMBOX1, NVL, NAF1, MAPK15, AURKB, NEK2, NEK7, GREM1 |
| positive regulation of telomerase catalytic core complex assembly | biological process | ATM, ATR |
| positive regulation of telomerase RNA localization to Cajal body | biological process | CCT5, CCT4, DKC1, SHQ1, CCT7, CCT2, TCP1, CCT6A, NOP10, RUVBL2, NHP2, CCT3, CCT8, RUVBL1, NAF1 |
| positive regulation of telomerase RNA reverse transcriptase activity | biological process | HNRNPD, HNRNPA2B1 |
| positive regulation of telomere capping | biological process | MAPK3, MAPK1, MAP3K4, HNRNPD, TNKS, MAPKAPK5, PRKCQ, RTEL1, MAP2K7, TNKS2, PKIB, NABP2, MAPK15, AURKB, NEK2, NEK7 |
| positive regulation of telomere maintenance | biological process | NBN, DHX36, ATRX, GNL3, RTEL1, MRE11, PML, RAD50, SIRT6, PPP1R10 |
| positive regulation of telomere maintenance via telomerase | biological process | MAPK3, MAPK1, ATM, CTNNB1, ATR, CCT5, CCT4, DKC1, CCT7, MAP3K4, HNRNPA1, XRCC5, PARN, CCT2, TCP1, CCT6A, TNKS, MAPKAPK5, POT1, CCT3, FBXO4, PRKCQ, MAP2K7, CCT8, TNKS2, PKIB, ACD, HMBOX1, NAF1, MAPK15, AURKB, NEK2, NEK7 |
| positive regulation of telomere maintenance via telomere lengthening | biological process | ATM, DHX36, HNRNPA2B1, RTEL1, NAF1 |
| positive regulation of telomeric DNA binding | biological process | PINX1 |
| positive regulation of telomeric loop disassembly | biological process | RTEL1 |
| positive regulation of telomeric RNA transcription from RNA pol II promoter | biological process | ATRX |
| positive regulation of tendon cell differentiation | biological process | GDF7 |
| positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled | biological process | SETX |
| positive regulation of the force of heart contraction | biological process | RYR2, SLC9A1, SLC8A1, MYL2 |
| positive regulation of the force of heart contraction by epinephrine-norepinephrine | biological process | ADRA1A, ADRB1 |
| positive regulation of thymocyte apoptotic process | biological process | TP53, ZC3H8, ADAM8 |
| positive regulation of thyroid hormone generation | biological process | HPN, GATA3, PAX8, SLCO1C1 |
| positive regulation of tight junction disassembly | biological process | TGFBR1 |
| positive regulation of timing of anagen | biological process | WNT10B |
| positive regulation of timing of catagen | biological process | TGFB2, MSX2, GAL |
| positive regulation of tissue remodeling | biological process | IL18, IL23A, IL2, IL21, IL15 |
| positive regulation of tolerance induction | biological process | HLA-G |
| positive regulation of tolerance induction to self antigen | biological process | TGFBR2 |
| positive regulation of tolerance induction to tumor cell | biological process | CD274 |
| positive regulation of toll-like receptor 2 signaling pathway | biological process | PJA2, CYBA, TIRAP, TLR1, MFHAS1 |
| positive regulation of toll-like receptor 3 signaling pathway | biological process | WDFY1, PELI1, TIRAP, PTPN22, FLOT1, CAV1 |
| positive regulation of toll-like receptor 4 signaling pathway | biological process | LTF, NR1H3, WDFY1, PELI1, TIRAP, PTPN22, TICAM2, LBP |
| positive regulation of toll-like receptor 7 signaling pathway | biological process | DDX3X, RSAD2, PTPN22, TREML4 |
| positive regulation of toll-like receptor 8 signaling pathway | biological process | DDX3X |
| positive regulation of toll-like receptor 9 signaling pathway | biological process | RTN4, RSAD2, PTPN22, HMGB1 |
| positive regulation of toll-like receptor signaling pathway | biological process | TLR2, TLR9, TLR3, TLR5 |
| positive regulation of tongue muscle cell differentiation | biological process | CYP26B1 |
| positive regulation of tooth mineralization | biological process | TFAP2A, WNT6 |
| positive regulation of TOR signaling | biological process | GAS6, LEP, SLC38A9, LAMTOR3, LAMTOR5, XBP1, SEC13, MIOS, RRAGA, RRAGB, SEH1L, LARS1, RHEB, GOLPH3, FNIP1, FLCN, SMCR8, RRAGD, HDAC3, LAMTOR1, TREM2, MLST8, WDR24, RPTOR, HTR6, WDR59, RELN, LIN28A |
| positive regulation of TORC1 signaling | biological process | GPR137B, LAMTOR5, SEC13, KLHL22, RRAGA, RRAGB, SEH1L, LARS1, GPR137, GPR137C, SIK3, FLCN, RRAGD, PIP4P1, CLEC16A |
| positive regulation of TORC2 signaling | biological process | SIK3 |
| positive regulation of TRAIL biosynthetic process | biological process | TNFRSF8 |
| positive regulation of TRAIL production | biological process | HLA-E |
| positive regulation of TRAIL-activated apoptotic signaling pathway | biological process | ATF3, PTEN, TIMP3 |
| positive regulation of transcription by glucose | biological process | SRF |
| positive regulation of transcription by transcription factor localization | biological process | KLF5 |
| positive regulation of transcription elongation from RNA polymerase II promoter | biological process | BRD4, TCERG1, ELOC, EAPP, SUPT16H, GTF2F1, ELL, CDC73, CDK13, GTF2F2, CDK12, LEO1 |
| positive regulation of transcription factor catabolic process | biological process | MAPK9, SIRT6, FBXW8 |
| positive regulation of transcription factor import into nucleus | biological process | CDH1 |
| positive regulation of transcription from RNA polymerase I promoter | biological process | ERBB2, WDR75, UBTF, ATF4, HEATR1, PHF8, DHX33, EIF2AK3 |
| positive regulation of transcription from RNA polymerase II promoter | biological process | NR5A2, EGFR, TGFB1, CGA, FSHB, TNF, IFNG, IL1B, ESR1, TP53, IL4, IL6, PGR, DCN, INHBA, AR, TGFB3, VDR, LIF, VEGFA, ATF3, TNFRSF1A, WT1, IL11, IL10, AHR, BRCA1, SOX9, NRIP1, SOX10, NR5A1, HIF1A, ESR2, IL23A, ZEB2, NR1I2, SERPINE1, SP1, ERCC2, HNF1A, FGFR2, MAPK3, AKT1, HNF1B, STAT1, GSK3B, HSF1, E2F1, HSF2, NFE2L2, CDKN2A, CTCFL, NODAL, ARNT2, PLAGL1, DMRT1, TLR4, TLR2, MTA2, IL1A, NR3C1, APP, HEXB, PARP1, BMP7, CTNNB1, STAT3, PARK7, DMRT2, IGF1, RB1, YES1, BMP4, HGF, ITGA6, IL2, NRG1, BMPR2, NCOA2, IL17A, SOHLH1, EBF2, PROP1, RAF1, THRB, OTX1, PPARG, GATA4, SOX2, CDK9, MEF2A, FOXO1, SHH, CLOCK, BRD4, TOP2A, USF1, ETV5, PKD1, CREM, NR1H3, SIN3A, NPAS2, TP63, TCF7L2, SOHLH2, IL33, MYC, MYCN, RBMX, GDNF, FOXM1, MAPK14, PATZ1, ETV2, CCN1, TCERG1, SHOX, HOXA3, GLI3, ARF4, CCNC, RBL1, HOXD13, TCF7, HDAC4, SUPT4H1, IRX6, HNRNPU, UBE3A, IKZF1, TFDP1, NR1D2, E2F5, ATAD2, SETD3, ZFPM2, COPS5, OVOL2, ZNF350, BCL11A, SENP2, TBK1, FOXJ3, RTRAF, DDX3X, KLF4, NPM1, PFKM, HOXD8, PAX7, DDIT3, SMARCA2, GTF2A2, CEBPG, ACTR3, MA |
| positive regulation of transcription from RNA polymerase II promoter by galactose | biological process | NCOA1 |
| positive regulation of transcription from RNA polymerase II promoter by glucose | biological process | USF1, USF2, FOXA2 |
| positive regulation of transcription from RNA polymerase II promoter in response to acidic pH | biological process | SLC38A3 |
| positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance | biological process | ATF4 |
| positive regulation of transcription from RNA polymerase II promoter in response to calcium ion | biological process | CARF |
| positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | biological process | TP53, ATF3, HSPA5, DDIT3, XBP1, ATF4, MBTPS2, CREB3L3, ATF6B |
| positive regulation of transcription from RNA polymerase II promoter in response to heat stress | biological process | HSF5, HSFX1, HSFY1, HSF4 |
| positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | VEGFA, HIF1A, NOTCH1, RBPJ, TP53 |
| positive regulation of transcription from RNA polymerase II promoter in response to iron | biological process | NFYA |
| positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological process | NFE2L2, ATF4, CHD6, MT3, SESN2 |
| positive regulation of transcription from RNA polymerase II promoter in response to stress | biological process | NFE2L2, MUC1, GCN1, ATF4, MAPK7, NFE2L1, KLF2, TP53 |
| positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | biological process | SMAD4, RELA, DLX5, RUNX2, BMP2, SMAD9, SMAD5 |
| positive regulation of transcription from RNA polymerase II promoter involved in heart development | biological process | NACA, GATA5, MYOCD |
| positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological process | MYOCD, SRF, GREM1 |
| positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process | biological process | HAND2 |
| positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation | biological process | MYOCD, ITGA8 |
| positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response | biological process | XBP1, CREB3, EP300 |
| positive regulation of transcription from RNA polymerase III promoter | biological process | AR, ERBB2, MTOR, ZC3H8, ICE2, ELL, ICE1, ZNF143, CHD8, RPTOR, BRF1 |
| positive regulation of transcription initiation from RNA polymerase II promoter | biological process | HNF1A, HNF1B, MED4, DHX36, SUB1, ERCC6, GTF2B, MED14, MED13, TAF6L, TAF6, MED30, GTF2F2, MED16, MED12, SRF, NKX2-5, MED24, PAXIP1 |
| positive regulation of transcription involved in exit from mitosis | biological process | SIRT7 |
| positive regulation of transcription involved in G1/S transition of mitotic cell cycle | biological process | ZPR1, ID2, ESRRB |
| positive regulation of transcription involved in G2/M transition of mitotic cell cycle | biological process | ESRRB |
| positive regulation of transcription involved in meiotic cell cycle | biological process | BRDT |
| positive regulation of transcription of Notch receptor target | biological process | DLGAP5, RBM15, CREBBP, NOTCH1, WWC1, PBX1, EP300, RBPJ, SNW1, MAML2, NOTCH4, NOTCH3, KAT2B, PLXND1, MAML1, MAML3 |
| positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter | biological process | MTOR, PWP1, MARS1, SMARCA4, SMARCB1, NOL11, NCL, DDX11, IPPK |
| positive regulation of transcription regulatory region DNA binding | biological process | TGFB1, PARP1, PARK7, IGF1, RB1, GATA3, NEUROD1, TWIST1, TRAF6, H1-0, POU4F1, POU4F2, NIBAN2, TRIM6, HAND2 |
| positive regulation of transcription via serum response element binding | biological process | MRTFA, SRF, MICAL2, NKX2-5 |
| positive regulation of transcription, DNA-templated | biological process | NR5A2, EGF, TGFB1, TNF, IFNG, IL1B, ESR1, TP53, IL4, IL6, INHBA, AR, TGFB3, WT1, IL10, AHR, BRCA1, SOX9, NRIP1, BRCA2, SOX10, NR5A1, HIF1A, ESR2, NR1I2, SP1, ERCC2, HNF1A, MAPK3, MAPK1, HNF1B, STAT1, E2F1, SRY, NFE2L2, CDKN2A, CTCFL, ARNT2, BMP7, CTNNB1, STAT3, IGF1, IL5, INSR, RB1, BMP4, SRC, SOHLH1, EBF2, CDH1, NR2F2, F2R, PPARG, GATA4, SOX2, MEF2A, FOXO1, SHH, CLOCK, USF1, ETV5, NR1H3, CAMK4, NPAS2, TP63, MYC, MYCN, CCNA2, FOXM1, PATZ1, TADA3, GLI3, HDAC4, IRX6, TFDP1, NR1D2, RNF20, ATAD2, BLOC1S2, SETD3, ZFPM2, WAC, NIF3L1, MED4, TRIM24, KLF4, PIAS1, NPM1, CD38, DDIT3, SMARCA2, NDP, CREB5, BAMBI, DYRK1A, KARS1, ELF2, FOXJ1, LBHD1, NUP85, ENY2, AIRE, ZIC2, CD74, SPI1, ESRRG, HIVEP3, BICRAL, ZNF398, NAT14, NSD1, GATA5, NSD3, CXXC1, CALCOCO1, ING1, USP16, FAM170A, ATMIN, SMARCA5, BCL10, SHC1, RFX3, SMARCA4, YWHAH, SMAD4, HNRNPD, NPAT, NCOA6, GPBP1, ABRA, DTX3L, HDAC2, RSF1, LGR4, LHX3, RNF14, FZD4, BTRC, DYRK1B, MAGED1, ARHGEF11, EOMES, PDGFB, BCL3, PPARD, RNF10, TP53INP1, NKX3-1, MAPRE3, SUPT3H, YEATS4, SPP |
| positive regulation of transcytosis | biological process | LRP1, PTAFR |
| positive regulation of transferrin receptor binding | biological process | B2M, HFE |
| positive regulation of transforming growth factor beta production | biological process | PTGS2, CD46, LGALS9, CD34, THBS1, SERPINF2 |
| positive regulation of transforming growth factor beta receptor signaling pathway | biological process | TGFBR3, SMAD4, GIPC1, DAB2, CREBBP, FERMT1, ING2, CITED1, SLC2A10, THBS1, TGFB1I1, CDKN2B, MEN1, GOT1, EP300, HIPK2, SDCBP, RNF111, SNW1, LRG1, MYOCD, FLCN, CITED2, CDKN1C, ITGA8 |
| positive regulation of transforming growth factor beta1 activation | biological process | FURIN |
| positive regulation of transforming growth factor beta1 production | biological process | CX3CL1, ATP6AP2, SERPINB7, THBS1 |
| positive regulation of transforming growth factor beta2 production | biological process | ATF2, WNT11 |
| positive regulation of transforming growth factor beta3 production | biological process | SMAD3 |
| positive regulation of transforming growth factor-beta secretion | biological process | FERMT1 |
| positive regulation of translation | biological process | IL6, FMR1, ERBB2, MAPK3, MAPK1, MTOR, PIWIL2, PABPC1, RPL5, EIF3E, RPS4X, PAIP1, DDX3X, EIF3D, NPM1, YTHDF1, SERP1, FXR1, DDX39B, HNRNPD, RPS27L, YTHDF3, BCL3, RPS6KB1, PLD1, PASK, UPF3A, RBM3, TARBP2, EEF2, NSUN5, THBS1, PYM1, NIBAN1, ITGA2, UCN, GUF1, PINK1, POLDIP3, RBMS3, EIF3C, SAMD4A, FXR2, CTIF, PRKDC, LARP6, UPF3B, CPEB3, KRT17, SOX4, EIF6, BARHL2, EIF2B5, ABCF1, MIF4GD, RPL26, CD28, PTAFR, PLXNB2, EIF4A3, PTK2B, LARP4B, NAT10, PCIF1, LIN28A |
| positive regulation of translation in response to endoplasmic reticulum stress | biological process | DDX3X, NCK1, NCK2 |
| positive regulation of translation initiation in response to endoplasmic reticulum stress | biological process | DNAJC3 |
| positive regulation of translational elongation | biological process | USP16, EIF5A, EIF5A2 |
| positive regulation of translational fidelity | biological process | CDK5RAP1, RPS9, EIF2S3 |
| positive regulation of translational initiation | biological process | DAZ1, DAZL, CCL5, KHDRBS1, BOLL, DDX3X, CDC123, YTHDF1, RPS6KB2, POLR2G, YTHDF3, RPS6KB1, UHMK1, POLR2D, DHX29, LARP1, HABP4, YTHDF2, EIF2B5 |
| positive regulation of translational initiation by iron | biological process | TNF |
| positive regulation of translational initiation in response to starvation | biological process | IMPACT |
| positive regulation of translational initiation in response to stress | biological process | PPP1R15A |
| positive regulation of translational termination | biological process | EIF5A, EIF5A2, JMJD4 |
| positive regulation of transmission of nerve impulse | biological process | IL6, ITGA2, CARTPT, HCRT, CHRNB4 |
| positive regulation of transport | biological process | SLC30A3 |
| positive regulation of transporter activity | biological process | PON1, SGK2, KCTD7, KMT2A, SGK1, SYNGR3 |
| positive regulation of triglyceride biosynthetic process | biological process | NR1H3, CNEP1R1, RGN, DGAT2, LDLR, SCARB1, SLC27A1, GPLD1, MFSD2A, SREBF1, CTDNEP1, NR1H2 |
| positive regulation of triglyceride catabolic process | biological process | ABHD5, AADAC, APOA1, APOA5, DAGLB, FGF21 |
| positive regulation of triglyceride lipase activity | biological process | PNLIP |
| positive regulation of triglyceride transport | biological process | LPCAT3 |
| positive regulation of trophectodermal cell proliferation | biological process | IGF1 |
| positive regulation of trophoblast cell migration | biological process | C1QBP, ACVR1B, AGO2, SMURF2 |
| positive regulation of tubulin deacetylation | biological process | FNTA |
| positive regulation of tumor necrosis factor (ligand) superfamily member 11 production | biological process | IFNG, ADAM8 |
| positive regulation of tumor necrosis factor biosynthetic process | biological process | TLR4, HSPB1, JAK2, AKAP12, CYBB, SYK, THBS1, TLR1, PSEN1, TNFRSF8, TYROBP, SPN, AZU1, LBP, AGER |
| positive regulation of tumor necrosis factor production | biological process | IFNG, IL23A, HLA-E, TLR4, TLR2, CLU, JAK2, ISL1, PIK3R1, HDAC2, LY96, CCL3, ARFGEF2, RASGRP1, NOD2, ZBTB20, CYBA, FADD, PF4, TIRAP, PTPRC, HMGB1, TWIST1, RIPK2, ARHGEF2, CD2, NFATC4, CCL19, CARD9, TLR9, FCER1G, PYCARD, TLR3, PTAFR, SPON2, NOD1, LBP, MAVS, CD36, TICAM1 |
| positive regulation of tumor necrosis factor secretion | biological process | AKAP12, IFIH1, LGALS9, LPL, LILRA5, IFNGR1, ORM1, HAVCR2, ORM2, LILRA2, FRMD8, FZD5, MMP8, LRRK2, MAVS |
| positive regulation of tumor necrosis factor-mediated signaling pathway | biological process | HSPA1A, HSPA1B, PRKN, TRIM32, CPNE1, UBE2K, TRAF2 |
| positive regulation of type 2 immune response | biological process | IL33, CD74, IDO1, NOD2, NLRP3, TNFSF4 |
| positive regulation of type B pancreatic cell apoptotic process | biological process | IL6, EIF2S1, CAPN10 |
| positive regulation of type B pancreatic cell development | biological process | BAD, RFX3 |
| positive regulation of type I hypersensitivity | biological process | BTK, FCER1G |
| positive regulation of type I interferon production | biological process | CTNNB1, TBK1, POLR2F, LRRFIP1, POLR3F, XRCC5, DHX36, IRAK1, MYD88, POLR1C, SYK, CREBBP, TRIM15, ZCCHC3, DHX58, POLR3K, XRCC6, RELA, POLR3A, ZBP1, DDX41, PTPN22, POLR3H, MRE11, POLR2L, NFKB2, POLR2E, EP300, PRKDC, POLR2K, IFI16, POLR3C, STING1, CGAS, PQBP1, IRF1, IRF7, POLR3GL, POLR3D, TLR3, POLR2H, POLR3E, IRF3, DHX33, STAT6, CRCP, PLCG2, POLR3B, TICAM1 |
| positive regulation of type I interferon-mediated signaling pathway | biological process | TBK1, LSM14A, FADD, IKBKE, ZBP1, UBE2K, IRF7, IRF3, MAVS, TRIM6 |
| positive regulation of type IIa hypersensitivity | biological process | C3, FCER1G |
| positive regulation of type III hypersensitivity | biological process | BTK, FCER1G |
| positive regulation of type III interferon production | biological process | TLR3 |
| positive regulation of type IV hypersensitivity | biological process | ZP3 |
| positive regulation of tyrosine 3-monooxygenase activity | biological process | PARK7 |
| positive regulation of tyrosine phosphorylation of STAT protein | biological process | CCL5, JAK2, IL15, ISL1, HDAC2, TSLP, ARL2BP, HES1, CTF1, IL13, PARP14, IL20, IFNL1, PIBF1, IL3, CSHL1, IL23R, GH2, GHR, LYN, CRLF1, OSM, HCLS1, TNFRSF18, IFNA2, STAP2, CSH1, PECAM1, IL24, IL31RA, EPO, CSF1R, PTK6, CD40, IL27RA, CLCF1, SOCS3, CSH2, CNTF, TNF |
| positive regulation of tyrosine phosphorylation of Stat1 protein | biological process | IFNG, LIF, TNFRSF1A, IL6ST, FGFR3, KIT, IL21 |
| positive regulation of tyrosine phosphorylation of Stat3 protein | biological process | IL6, IL6R, LIF, VEGFA, IL6ST, IL18, IL23A, FGFR3, STAT3, LEP, GH1, KIT, IL21 |
| positive regulation of tyrosine phosphorylation of Stat4 protein | biological process | IL12A, IL23A |
| positive regulation of tyrosine phosphorylation of Stat5 protein | biological process | IL4, IL23A, GH1, IGF1, KIT, IL2 |
| positive regulation of ubiquitin protein ligase activity | biological process | PTEN, CDC20, SKP1, RAB1A, FZR1, BTRC, MASTL, GORASP1, PLK1, CDC20B, CDC14B, UBE2C, GOLGA2, UBE2S |
| positive regulation of ubiquitin-dependent endocytosis | biological process | TSG101, VPS28 |
| positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition | biological process | CDK1, CCNB1, CDC20, PSMA3 |
| positive regulation of ubiquitin-protein transferase activity | biological process | DCUN1D1, DCUN1D4, TRIB3, PIN1, FBXW7, RPS2, MAGEA2, UBE2N, ARRDC4, DCUN1D5, STUB1, AXIN1, PINK1, PLK1, BMI1, UBE2L3, ARRDC3, MAGEC2, DCUN1D2, TOPORS |
| positive regulation of ubiquitin-specific protease activity | biological process | TANK |
| positive regulation of unsaturated fatty acid biosynthetic process | biological process | ABCD2, ABCD1 |
| positive regulation of ureter smooth muscle cell differentiation | biological process | SHH |
| positive regulation of ureteric bud formation | biological process | GDNF, GATA3, SIX1, SIX4 |
| positive regulation of urine volume | biological process | GNAI2, HAS2, NPR3, EDNRB, INPP5K, HYAL2, NPR1, BTC, EDN1, DRD2, OPRL1, ADORA2A |
| positive regulation of urothelial cell proliferation | biological process | FGF10 |
| positive regulation of uterine smooth muscle contraction | biological process | TACR3, OXTR, OXT, TACR2, ABAT, ADRA2B, GPER1 |
| positive regulation of vacuole organization | biological process | ELAPOR1 |
| positive regulation of vascular associated smooth muscle cell apoptotic process | biological process | STK4, E2F3, PDCD4, ATF4, MFN2 |
| positive regulation of vascular associated smooth muscle cell migration | biological process | IQGAP1, PDGFB, XBP1, DOCK5, DOCK7, ATP7A, LRP1, SSH1, NR4A3, IGFBP5, AGT, DOCK4 |
| positive regulation of vascular endothelial cell proliferation | biological process | GHSR, MDK, HMGB1, SIRT6, FGF2, PDPK1 |
| positive regulation of vascular endothelial growth factor production | biological process | TGFB1, IL1B, PTGS2, BRCA1, IL6ST, HIF1A, NODAL, C3, IL1A, GATA4, CYP1B1, HPSE, ISL1, CCBE1, NOX1, FLT4, C5, ATF4, RORA, C3AR1, SULF1, ADORA2B, SULF2, EIF2AK3, C5AR1 |
| positive regulation of vascular endothelial growth factor receptor signaling pathway | biological process | IL1B, VEGFA, HIF1A, FLT1, ITGA5, FGF9, GRB10, PRKCB, ITGB3, FGF18, VTN, MT3, PRKD2, VEGFB, FGF10 |
| positive regulation of vascular endothelial growth factor signaling pathway | biological process | CCBE1, JCAD, SMOC2, MYO1C, ADAMTS3, ROBO1 |
| positive regulation of vascular permeability | biological process | TGFB1, VEGFA, FGFBP3, CXCR2, UCN, PDE3A, TACR2, BMP6, PTP4A3, VEGFB, PDE2A |
| positive regulation of vascular smooth muscle cell dedifferentiation | biological process | PDGFB |
| positive regulation of vascular smooth muscle cell differentiation | biological process | KIT, ENG |
| positive regulation of vascular smooth muscle cell proliferation | biological process | JAK2, GNAI2, DDX39B, PDGFB, XBP1, GNAI3, BMPR1A, HPGD, FOXJ2, ERN1, MFN2, MEF2D, MAP3K5, HTR1B, EDN1, FGF2, NR4A3, NQO2, IGFBP5, P2RY6, AGT, TNF |
| positive regulation of vascular smooth muscle contraction | biological process | CHRM3 |
| positive regulation of vascular wound healing | biological process | CXCR4, XBP1, FOXC2, SMOC2, VEGFB |
| positive regulation of vasculogenesis | biological process | ADM, KDR, RAP1A, RIN2, RAPGEF2, RRAS, CD34, RAMP2, TMEM100, HIF1AN, CEACAM1 |
| positive regulation of vasoconstriction | biological process | ICAM1, PTGS1, PTGS2, AKT1, GJA1, F2R, OXTR, CD38, HRH1, FGG, FGB, ADRA1A, AVPR2, GJA5, AVPR1B, AVP, ADRA1D, FGA, PTAFR, ADRA1B, TRPM4, ADRA2C, HRH2, DBH, TBXA2R, SMTNL1, CAV1 |
| positive regulation of vasodilation | biological process | NOS3, ADM, ESR2, HMOX1, NOS2, GJA1, EPHX2, PLA2G6 |
| positive regulation of very-low-density lipoprotein particle remodeling | biological process | APOA5 |
| positive regulation of vesicle fusion | biological process | ANXA2, KIF5B, C2CD5, ANXA1, SYT1, AKT2, DOC2B |
| positive regulation of viral budding via host ESCRT complex | biological process | TSG101, VPS37B |
| positive regulation of viral entry into host cell | biological process | CD74, LGALS9, P4HB, TRIM11, TMPRSS2, TRIM38, CD4, TRIM21 |
| positive regulation of viral genome replication | biological process | NR5A2, RAD23A, PABPC1, CCL5, TOP2A, DDX3X, ADARB1, VAPB, STAU1, ADAR, SRPK1, TMEM39A, SRPK2, TARBP2, NOTCH1, IFIT1, PPID, PKN2, HACD3, TRIM38, LARP1, PPIH, PPIE, CD28, PPIA, DDB1 |
| positive regulation of viral life cycle | biological process | KPNA2, VPS4B, KPNA6 |
| positive regulation of viral process | biological process | VPS4B, STOM, RAB7A, TMEM250 |
| positive regulation of viral release from host cell | biological process | CHMP2A, TSG101, VPS4B, CHMP4B, VPS37B, CHMP4C, CHMP3, DDB1 |
| positive regulation of viral transcription | biological process | CDK9, SUPT4H1, POLR2F, NELFCD, POLR2G, RSF1, NELFA, CCNT1, GTF2F1, GTF2B, POLR2B, SUPT5H, POLR2D, NELFE, POLR2J, POLR2L, POLR2E, POLR2K, MDFIC, POLR2I, GTF2F2, POLR2C, NELFB, POLR2H, POLR2A, CTDP1 |
| positive regulation of vitamin D 24-hydroxylase activity | biological process | VDR, FGF23, CYP27B1 |
| positive regulation of vitamin D biosynthetic process | biological process | TNF, IFNG |
| positive regulation of vitamin D receptor signaling pathway | biological process | CYP27B1, SNW1 |
| positive regulation of voltage-gated calcium channel activity | biological process | STAC2, CDK5, EHD3, CACNB3, STAC3, KCNE3, S100A1 |
| positive regulation of voltage-gated chloride channel activity | biological process | CFTR, PTAFR |
| positive regulation of voltage-gated potassium channel activity | biological process | LRRC26, LRRC52, KCNIP2, KCNC1, KCNC2, KCNA1, AMIGO1, LRRC55 |
| positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | biological process | NOS1AP |
| positive regulation of voltage-gated sodium channel activity | biological process | KIF5B |
| positive regulation of white fat cell proliferation | biological process | FGF10 |
| positive regulation of Wnt protein secretion | biological process | WLS, PTPN23, VPS35 |
| positive regulation of Wnt signaling pathway | biological process | TERT, ZEB2, FGFR2, KANK1, MBD2, TLR2, SHH, ATP6AP2, SMARCA4, WLS, MACF1, DISC1, PCDH11Y, SKI, CDC73, RSPO2, CSNK2A1, DEPDC1B, ZRANB1, RSPO3, DACT1, BMP2, SULF1, SALL1, HHEX, LGR6, ATP6V0C, WNT3, CCN4, SULF2, ATP6V1C2, DIXDC1, FGF10 |
| positive regulation of Wnt signaling pathway by BMP signaling pathway | biological process | BMP2 |
| positive regulation of Wnt signaling pathway, calcium modulating pathway | biological process | DKK1 |
| positive regulation of Wnt signaling pathway, planar cell polarity pathway | biological process | DAB2, DKK1, PLEKHA4, ANKRD6, MLLT3, ABL1, RSPO3, GPC3, NKD1 |
| positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation | biological process | CSNK1E, CSNK1D |
| positive regulation of wound healing | biological process | INSL3, KANK1, ARFGEF1, REG3A, PTK2, ANXA1, REG3G, ADRA2A, ACTG1, HBEGF, PRKCE, DUOX2, VTN, HRAS, DMTN, CLDN1, CLDN4, MYLK, DUOX1, CCN4 |
| positive regulation of wound healing, spreading of epidermal cells | biological process | RREB1 |
| positive regulation of xenophagy | biological process | MAPK3, OPTN, TBK1, RIPK2, NOD1, LRSAM1 |
| positive T cell selection | biological process | BCL11B, THEMIS |
| positive thymic T cell selection | biological process | SHH, CD74, ITPKB, ZAP70, PTPRC, CD3E, CD3G, SRF, DOCK2 |
| post-anal tail morphogenesis | biological process | TP63, TRAF3IP1, DCHS1, WNT3A, FZD3, SCRIB, TMED2, HES7, VANGL2, PALB2, MED12, SFRP2, EPHA2, TCF15, CHST11 |
| post-chaperonin tubulin folding pathway | biological process | TBCC, TBCA, TBCE, TBCD, RP2 |
| post-embryonic animal organ development | biological process | LDHA |
| post-embryonic animal organ morphogenesis | biological process | BCL2L11, MYO7A |
| post-embryonic body morphogenesis | biological process | GNAS |
| post-embryonic camera-type eye development | biological process | VEGFA, KLF4, BCL11B, FZD5 |
| post-embryonic camera-type eye morphogenesis | biological process | BAX, BAK1, HMGN1 |
| post-embryonic cardiac muscle cell growth involved in heart morphogenesis | biological process | SIRT6 |
| post-embryonic development | biological process | BCL2, BAX, GNAS, APOB, CYP1A2, ERCC2, FGFR2, MTOR, IGF2R, BMP4, EMX1, PYGO2, KDM5B, NDN, STK36, SERP1, BCL2L11, MORC3, C12orf57, PLEKHA1, ETNK2, BPNT2, IREB2, ARID5B, ACVR2B, NKX2-3, PRDM1, GABRG2, GATA3, SELENOP, TIPARP, BCL11B, RC3H2, NR4A2, LHX1, PSEN1, MECP2, ABL1, CSRNP1, AGO2, FOXP2, SOX6, TGFBR1, SZT2, CCDC47, ITPR1, SMAD2, ASH1L, PLAGL2, ALX4, ALDH5A1, SCUBE1, SEMA3C, MYL2, TAL2, GIGYF2, DHCR7, ACO1, NPPC, SLC18A2, CHST11, SLC4A10, PPP1R13L |
| post-embryonic digestive tract morphogenesis | biological process | NKX2-3 |
| post-embryonic eye morphogenesis | biological process | FBN1, MFAP2, EFEMP1 |
| post-embryonic forelimb morphogenesis | biological process | ATRX |
| post-embryonic hemopoiesis | biological process | ERCC1, KLF4 |
| post-embryonic retina morphogenesis in camera-type eye | biological process | CRB1, DSCAM |
| post-Golgi vesicle-mediated transport | biological process | SNAP23, SCFD1, VAMP8, ARL3, MYO5A, SCAMP1, EXOC5, MYO1B, VAMP7, SCAMP2, SORT1, RABIF, SORL1, STX4, GBF1, SORCS1, RP2 |
| post-transcriptional gene silencing by RNA | biological process | AGO4, AGO3, HELZ, AGO2, TNRC6B, TNRC6A, TNRC6C, MOV10, AGO1 |
| post-translational protein acetylation | biological process | DSCC1, ESCO1 |
| post-translational protein modification | biological process | ARSA, CCN1, PSMB1, PSMB5, PSMC2, ELOC, DCAF17, PSMA8, DCAF11, COPS5, FEM1C, NUB1, PSMA7, CALU, LAMC1, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, RAB11A, KEAP1, FBXO11, ASB12, DCUN1D1, PSMB7, COPS8, DDA1, CISH, WSB2, SOCS2, RAB38, SKP1, LTBP1, PSMD6, RBBP7, CUL9, FBXO15, COP1, ASB17, PSMD1, KLHL25, FBXL5, HIF3A, PSMD14, PSMD7, RAB1A, RCN1, FBXL22, COPS6, FBXW7, FBXO17, TULP4, DCAF13, FBXL12, BTRC, SOCS5, PROC, P4HB, IGFBP1, HSP90B1, ITIH2, PSMB6, FBN1, RAB2A, RBBP5, KTN1, FBXL13, STT3B, ANKRD9, ASB8, FBXO9, PSMD10, SPP1, CHML, PSMD8, RABGGTB, PSMC5, NAE1, KLHL22, DDB2, COPS4, EVA1A, FN3KRP, DTL, FBXO2, MGAT4A, PSMB4, SDC2, DCAF7, WDR5, PSME1, CUL1, MBTPS1, PDIA6, DCAF6, ASB16, UBD, FGG, RAB5A, PSMB8, PSMD4, DCAF8, SPSB3, GOLM1, ASB7, VIPAS39, FEM1B, FBXO4, QSOX1, PSMC3, STT3A, PSMA6, APLP2, MFGE8, FSTL1, ERCC8, FBXO30, FGF23, DCAF16, FBXO10, FBXL4, UBXN7, FSTL3, COPS2, NEDD8, FBXO32, WSB1, KLHL41, CKAP4, IGFBP7, FAM20C, KCTD7, ATG5, MEN1, FBXL16, DCAF4, SCG3, CUL5, AMBN, FBXW10, FBXL3, STC2, PRSS23, APOA1, PRKCSH, SKP |
| posterior compartment specification | biological process | PBX3 |
| posterior lateral line neuromast hair cell development | biological process | TMEM132E |
| posterior mesonephric tubule development | biological process | WT1 |
| posterior midgut development | biological process | EDNRB, RET |
| postganglionic parasympathetic fiber development | biological process | GDNF, PLXNA4 |
| postreplication repair | biological process | BRCA1, UBE2B, MSH2, POLH, UBE2N, UBE2NL, UBE2V1, UBE2V2, NSMCE1, WDR33, RAD18 |
| postsynapse assembly | biological process | WNT7A |
| postsynapse organization | biological process | FZD9, DVL1, DNM3, SPTBN2, CNKSR2, ACTN1, NDRG1, NRP1, SHANK1, ARHGAP39 |
| postsynapse to nucleus signaling pathway | biological process | JAK2, KPNA2, WNT3A, RELA, KPNA1, CRTC1, PRR7 |
| postsynaptic actin cytoskeleton organization | biological process | MYH10, ACTL8, NOS1AP, CTTN, ARF1, DBNL, WASF2, ACTG1, HCLS1, PPP1R9A, ACTBL2, FRMPD4, INA |
| postsynaptic density assembly | biological process | PTEN, SHANK2, SHANK1 |
| postsynaptic density organization | biological process | TMEM108 |
| postsynaptic density protein 95 clustering | biological process | NRXN1, NLGN2, NRXN2, LRRC4, RELN |
| postsynaptic intermediate filament cytoskeleton organization | biological process | NEFH, INA, NEFL |
| postsynaptic membrane assembly | biological process | NLGN4X, EPHB2, NRXN1, NLGN2, NRXN2, NLGN4Y, LRP4 |
| postsynaptic membrane organization | biological process | GDNF, CHRNB1 |
| postsynaptic modulation of chemical synaptic transmission | biological process | SYNPO, GHSR, DCC, PPP3CA, DRD2, NRGN, GRM5 |
| postsynaptic neurotransmitter receptor cycle | biological process | NSG1 |
| postsynaptic neurotransmitter receptor diffusion trapping | biological process | CACNG2, CACNG3, GPHN, DLG4, CACNG4, SHISA6, CACNG8 |
| postsynaptic neurotransmitter receptor internalization | biological process | EPS15, DNM3, MX1, AP2B1, MX2, CALY, DNM1 |
| postsynaptic specialization assembly | biological process | NLGN2, NTNG2 |
| posttranscriptional gene silencing | biological process | PUM1, MARF1, GIGYF2 |
| posttranscriptional regulation of gene expression | biological process | PUM2, NANOS1, MATR3, TDRD7, NUDT21, PUM1, PER1, ZC3H7A, YTHDC1, FBXO4, ZC3H10, GCNT2, RC3H2, EPB41L5, RC3H1, TRIM71, ZC3H7B, SPOUT1, METTL16, CDC37, CAV1 |
| posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery | biological process | NUP107, PCID2, NUP98 |
| posttranslational protein targeting to endoplasmic reticulum membrane | biological process | GET1, SGTA, SEC63, SEC62, CHMP4A, CHMP4B, GET3, SEC61A1 |
| posttranslational protein targeting to membrane, translocation | biological process | SEC63, SEC62, SEC61G, SEC61B, SEC61A2, SEC61A1 |
| potassium ion export across plasma membrane | biological process | KCNH2, KCND3, KCNT2, KCNE4, KCNK18, KCNE1, KCNA2, KCNIP2, KCNE3 |
| potassium ion homeostasis | biological process | CYP11B2, ATP6V1B1, KCNJ10, SLC12A2, KCNH2, SLC12A6, SLC12A4, SLC12A9, SLC12A7, SLC12A5, SLC12A3, UPK3A, SLC12A8 |
| potassium ion import across plasma membrane | biological process | KCNJ10, SLC12A2, KCNJ16, KCNH2, SLC12A6, ATP1A4, SLC12A4, ABCC9, ATP1A3, ATP1A2, KCNJ15, KCNJ4, HCN2, ATP1B1, KCNJ2, SLC12A9, SLC12A7, FXYD2, SLC12A5, ATP1A1, ATP1B2, KCNJ9, KCNJ8, ATP4A, ATP1B3, HCN4, KCNJ12, SLC12A3, KCNJ1, SLC12A8, ATP4B |
| potassium ion transmembrane transport | biological process | KCNK9, KCNK17, KCNK4, KCNJ10, KCNAB1, KCNH6, KCNN3, KCNMB1, KCNK2, KCNMB3, LRRC26, SLC24A5, SLC24A4, KCNH3, KCNH4, KCNA4, KCNH2, KCNN1, KCND3, KCNN4, CCDC51, SLC9C1, TMEM38B, KCND2, SLC9A2, SLC9A1, KCNIP4, SLC9A7, HPN, SLC1A3, PKD2, KCND1, PKD2L1, KCNQ3, FXYD4, ATP1A4, SLC9A9, P2RY12, KCNG1, KCNQ2, KCNK10, KCNG4, ABCC9, SNAP25, KCNC4, LRRC52, ATP1A2, KCNB1, SLC9C2, KCNT2, KCNE4, KCNV1, KCNK18, KCNF1, SLC24A3, HCN2, ATP1B1, KCNA6, AQP1, KCNJ2, KCNV2, KCNS3, KCNIP1, KCNG2, KCNK1, HCN1, SLC9A6, KCNK15, KCNAB3, KCNE1, KCNA2, KCNIP2, KCNK3, KCNC1, KCNQ4, KCNJ8, KCNC2, ATP1B3, KCNAB2, ABCB8, KCNK7, HCN4, KCNA3, KCNA1, KCNT1, TRPM5, KCNIP3, ABCC8, KCNH8, TMEM175, KCNMA1, KCNC3, KCNMB4, NALCN, KCNH5, KCNG3, KCNN2, LRRC55, CCT8L2, KCNK13, KCNQ5, KCNK6, KCNE3, SLC24A1, KCNH7 |
| potassium ion transport | biological process | KCNK9, KCNK17, KCNK4, KCNJ10, KCNAB1, KCNH6, KCNN3, SLC12A2, KCNMB1, KCNJ16, KCNK2, KCNMB3, VPS4B, NSF, SLC24A5, SLC24A4, KCNH3, KCNH4, KCNA4, KCNH2, KCNN1, KCND3, FXYD1, KCNN4, TSC1, CCDC51, TMEM38B, KCND2, SLC12A6, KCNIP4, SLC9A7, PKD2, KCND1, KCNQ3, ATP1A4, KCNG1, SLC12A4, KCNQ2, KCNK10, FXYD3, KCNG4, ABCC9, ATP1A3, KCNC4, LRRC52, ATP1A2, KCNB1, KCNJ15, CDKN1B, KCNT2, KCNE4, CHP1, KCNJ4, KCNV1, KCNK18, KCNF1, SLC24A3, HCN2, ATP1B1, KCNA6, AQP1, GJA5, KCNJ2, KCNV2, KCNS3, KCNIP1, KCNG2, SLC12A7, KCNK1, HCN1, FXYD2, SLC12A5, KCNK15, KCNAB3, ATP1A1, ATP1B2, KCNE1, KCNA2, KCNJ9, KCNIP2, KCNK3, KCNC1, KCNQ4, KCNJ8, KCNC2, ATP4A, ATP1B3, KCNAB2, ABCB8, KCNK7, HCN4, KCNA3, KCNA1, KCNJ12, KCNT1, KCNIP3, ABCC8, KCNH8, TMEM175, KCNJ1, KCNMA1, KCNC3, KCNMB4, KCNH5, KCNG3, KCNN2, SLC12A8, KCNK13, KCNQ5, KCNK6, KCNE3, ATP4B, KCNH7 |
| pre-B cell allelic exclusion | biological process | RAG1, ATM, RAG2 |
| pre-miRNA export from nucleus | biological process | RAN |
| pre-miRNA processing | biological process | LIN28B, DROSHA, DICER1, AGO4, PRKRA, ADAR, TARBP2, AGO3, AGO2, AGO1, TUT4, MRPL44, TUT7, LIN28A |
| pre-mRNA catabolic process | biological process | ZPR1 |
| pre-mRNA cleavage required for polyadenylation | biological process | CSTF2, TUT1, CPSF2, NUDT21, NCBP2, CPSF4, NCBP1, CPSF7, CPSF1, CPSF6 |
| pre-replicative complex assembly involved in nuclear cell cycle DNA replication | biological process | MCM3, ORC3, MCM5, MCM4, MCM7, MCM6, MCM2 |
| preantral ovarian follicle growth | biological process | AMH, ZNF830 |
| preassembly of GPI anchor in ER membrane | biological process | PIGX, PIGA, PIGH, PIGM, PIGP, PIGV, PIGN, PIGF, PIGB, PIGG, PIGL, DPM2, PIGW, PIGQ, PIGY |
| prechordal plate formation | biological process | SSBP3 |
| prenylated protein catabolic process | biological process | PCYOX1, ZMPSTE24 |
| prenylcysteine catabolic process | biological process | PCYOX1 |
| prepulse inhibition | biological process | PTEN, GRIN1, DVL1, CTNNA2, FABP7, DRD3, GRIN3A, GRID2, DRD1, BACE1, CHD8, DRD2, ADORA2A, SLC6A3 |
| pressure natriuresis | biological process | CYP4A11, CYP4F12, CYP4F2 |
| presynapse assembly | biological process | NLGN4X, DVL1, CNTN5, NLGN2, WNT3A, NLGN4Y, EFNB2, FZD1, WNT7A |
| presynapse organization | biological process | PPFIA2, C5AR1 |
| presynapse to nucleus signaling pathway | biological process | BSN |
| presynaptic active zone assembly | biological process | PCDH17, BSN |
| presynaptic active zone organization | biological process | CAST |
| presynaptic dense core vesicle exocytosis | biological process | UNC13C, UNC13B, SYT6, UNC13A |
| presynaptic membrane assembly | biological process | PTEN, IL1RAPL1, NLGN4X, NRXN1, NLGN2, NLGN4Y, LRP4, PTPRD |
| presynaptic membrane organization | biological process | CNTN2 |
| presynaptic modulation of chemical synaptic transmission | biological process | GIT1, PRKCB, HTR1B, PRKCG |
| prevention of polyspermy | biological process | ASTL |
| pri-miRNA transcription by RNA polymerase II | biological process | SMAD4 |
| primary adaptive immune response involving T cells and B cells | biological process | BACH2 |
| primary follicle stage | biological process | EREG |
| primary heart field specification | biological process | MEF2C, WNT11 |
| primary lung bud formation | biological process | RDH10 |
| primary miRNA processing | biological process | DROSHA, HNRNPA2B1, PUS10, SRRT, SMAD2, MRPL44, SMAD3 |
| primary ovarian follicle growth | biological process | FSHR |
| primary palate development | biological process | HAND2 |
| primary prostatic bud elongation | biological process | SHH |
| primary sex determination | biological process | NR5A1 |
| primary ureteric bud growth | biological process | LZTS2 |
| primitive erythrocyte differentiation | biological process | VEGFA, ZFPM1 |
| primitive hemopoiesis | biological process | STK3, STK4, THOC5 |
| primitive streak formation | biological process | NODAL, LRP6, LHX1, SRF, GDF3, ETS2, FOXA2 |
| principal sensory nucleus of trigeminal nerve development | biological process | KIRREL3, NFIB |
| pro-B cell differentiation | biological process | LIG4, PRKDC, SOX4 |
| pro-T cell differentiation | biological process | GATA3 |
| production of miRNAs involved in gene silencing by miRNA | biological process | DICER1, PUM1, ZC3H7A, AGO4, SNIP1, PRKRA, ADAR, TARBP2, AGO3, AGO2, TRIM71, ZC3H7B, AGO1, SPOUT1 |
| production of molecular mediator involved in inflammatory response | biological process | IL4R, CD36 |
| production of siRNA involved in RNA interference | biological process | TERT, DROSHA, DICER1, PRKRA, HENMT1, TARBP2, TSN, AGO2, TSNAX, MRPL44 |
| proepicardium cell migration involved in pericardium morphogenesis | biological process | FLRT3 |
| progesterone biosynthetic process | biological process | FSHB, LHB, ADM, SCP2, STARD3 |
| progesterone metabolic process | biological process | CYP17A1, SRD5A1, AKR1C3, STAT5B, DHRS9, AKR1C2, CYP46A1, AKR1C1, AKR1C4 |
| progesterone receptor signaling pathway | biological process | SRC, UBE3A, UBR5, NEDD4, YAP1, WBP2 |
| progesterone secretion | biological process | INHBA, FZD4 |
| programmed cell death | biological process | TP53, CASP4, DNM1L, TOP1, PDCD2, GSDME, STK17B, ALKBH7, HTRA2, PKM, CAPN3, GSDMB, PPIF, P2RX7, RIPK3, DNASE1L3, PGAM5, GSDMD, RNF130, GSDMA, GSDMC |
| programmed cell death involved in cell development | biological process | NTRK1, DNASE1L3 |
| programmed necrotic cell death | biological process | CASP1, MAP3K5, RIPK3, IRF3, TRAF2 |
| prolactin secreting cell differentiation | biological process | PITX2 |
| prolactin secretion | biological process | UBE2Q1, ANXA1, TACR2 |
| prolactin signaling pathway | biological process | PRLR |
| proline biosynthetic process | biological process | PYCR2, ALDH18A1, PYCR1, PYCR3 |
| proline catabolic process | biological process | DAO, PRODH2, ALDH4A1 |
| proline catabolic process to glutamate | biological process | PRODH2, ALDH4A1 |
| proline metabolic process | biological process | PRODH2, ALDH4A1 |
| proline transmembrane transport | biological process | SLC36A1, SLC1A4, SLC36A2, SLC36A3, SLC6A7 |
| proline transport | biological process | SLC6A20, SLC36A4, SLC36A1, SLC1A4, SLC6A15, SLC36A2, SLC6A7, SLC6A17 |
| prolyl-tRNA aminoacylation | biological process | EPRS1, PARS2 |
| pronephric duct morphogenesis | biological process | AHI1 |
| pronephric field specification | biological process | PAX8 |
| pronephric nephron development | biological process | SEC61A1 |
| pronephric nephron tubule development | biological process | HNF1B |
| pronephric nephron tubule morphogenesis | biological process | AHI1 |
| pronephros development | biological process | HNF1B, PAX8, LHX1, CEP290 |
| pronuclear fusion | biological process | CDK1 |
| propanoate transport | biological process | SLC5A8 |
| propionate biosynthetic process | biological process | ACSS1, ACSS2 |
| propionate catabolic process | biological process | PCK2 |
| proprioception | biological process | FXN, MECP2, GBX1 |
| proprioception involved in equilibrioception | biological process | POU4F1 |
| propylene metabolic process | biological process | GRIN1 |
| prostaglandin biosynthetic process | biological process | PTGS1, PTGS2, MIF, PTGDS, PNPLA8, PTGES3, CD74, PRXL2B, PTGES2, PTGES, PTGIS, PLA2G4A, DAGLB, HPGDS, EDN1, TBXAS1 |
| prostaglandin catabolic process | biological process | ABHD16A |
| prostaglandin metabolic process | biological process | TNFRSF1A, PTGS1, PTGS2, AKR1C3, PTGDS, ATP6V1B1, PTGR1, PTGES3, AKR1C2, GSTA1, PRXL2B, HPGD, CYP4F8, ZADH2, PTGES2, PTGES, PTGIS, PLA2G4A, PTGR2, PLAA, HPGDS, TBXAS1, CES2, CYP2S1, ACOX1, AKR1C1, AKR1C4 |
| prostaglandin secretion | biological process | LEP, NOS2, ABCC4 |
| prostaglandin transport | biological process | SLCO2A1, SLCO3A1 |
| prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis | biological process | ESR1, FGFR2, HOXD13, FRS2, HOXB13 |
| prostate epithelial cord elongation | biological process | ESR1, FGFR2, SHH |
| prostate gland development | biological process | AR, SOX9, FKBP4, ESR2, SHH, TP63, GLI3, HOXD13, NKX3-1, ANXA1, SMARCC1, GLI1, HOXB13, ALOX15B, PTCH1, RARA |
| prostate gland epithelium morphogenesis | biological process | FOXA1, NOTCH1, ID4, TNC, RARG |
| prostate gland growth | biological process | CYP19A1, PRLR, PTEN, UBE3A, PSAP |
| prostate gland morphogenesis | biological process | SOX9, FGFR2, BMP4, ID4, SERPINB5 |
| prostate gland stromal morphogenesis | biological process | FOXA1, CRIP1, ID4 |
| prostatic bud formation | biological process | TP63, GLI2, FGF10 |
| proteasomal protein catabolic process | biological process | PSMB1, PSMB5, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, PRPF19, PSMB6, RNF41, PRKN, PSMB4, PSMB8, PSMA6, PSMB9, ATE1, PSMA4, NR1D1, PSMB3, SOCS6, MARCHF6, FBXO44, DDI1, DDB1, PSMB10 |
| proteasomal ubiquitin-independent protein catabolic process | biological process | NFE2L2, PSMB1, PSMB5, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, PSMB6, PSMB4, PSMB8, PSMA6, PSMB9, ENC1, PSMA4, PSMB3, PSMB10 |
| proteasome assembly | biological process | POMP, PSMG1, PSMD4, ADRM1, PSMG4, PSMD5, PSMG2, PSMD13 |
| proteasome core complex assembly | biological process | PSMG1 |
| proteasome regulatory particle assembly | biological process | PSMD10, PSMD9, PSMD5 |
| proteasome-mediated ubiquitin-dependent protein catabolic process | biological process | TP53, CDK1, GSK3B, UBE2B, NFE2L2, CTNNB1, RAD23A, RAD23B, CDC20, CLOCK, PSMA3, PSMB1, PSMB5, PSMC2, UBE2D3, SIAH1, PSMA8, DCAF11, RNF34, UBE2W, HECW2, PSMA7, PSMA1, PSMA2, PSMA5, DDIT3, PSMB2, PSMC6, ITCH, CRBN, PSMB7, TRIM13, PSMD6, COP1, PSMD1, EDEM3, PSMD14, SIAH2, LTN1, PSMD7, FBXL22, ARMC8, FBXW7, FAF2, PELI1, DERL1, BTRC, PSMB6, UBE2G1, TNFAIP1, TRIM3, PSMD10, PSMD8, PSMC5, PPP2R5C, KIF14, KLHL22, KCTD13, TRIM9, TRIM2, PRKN, PSMB4, UBE2H, PSME1, CUL1, TRIM44, PSMB8, PSMD4, UBXN2A, SPSB3, MAEA, RMND5A, STUB1, PSMC3, PSMA6, ERCC8, UFD1, GID4, SIRT2, ZFAND2B, NEDD4, UBE2U, ATXN3, CUL5, AGAP3, BIRC2, USP44, FBXL17, FBXL3, NSFL1C, SPOP, SKP2, SIAH3, PCNP, KAT5, SHARPIN, PSMD12, TRIM38, PSMB9, PSMC4, CUL2, RNF187, RMND5B, NEDD4L, PSMD9, WWP2, PSMA4, IFI27, PSMD2, UBXN2B, HACE1, RBCK1, WWP1, GID8, KLHL20, PML, CDC34, HECW1, RNF126, UBE2K, PCBP2, PSMD5, TRIM71, PSMF1, FAF1, CD2AP, TBL1X, UBE4B, PSMB3, KCTD10, MARCHF6, KCTD17, TBX21, PLAA, PSMD3, PSMC1, RBX1, SPSB1, RNF122, KCTD5, ARNTL, FBXL19, ZNRF1, TRIM54, T |
| protection from natural killer cell mediated cytotoxicity | biological process | HLA-B, HLA-E, SERPINB9 |
| protection from non-homologous end joining at telomere | biological process | TERF2IP, DCLRE1C, DCLRE1B, ACD, DCLRE1A, TFIP11 |
| protein acetylation | biological process | FOXO1, GTF2B, CREBBP, NUPR1, EP300, NAA80, NAA10, KAT6A, KAT2B, ING5, ING4 |
| protein acylation | biological process | ZDHHC6 |
| protein adenylylation | biological process | FICD, SELENOO |
| protein ADP-ribosylation | biological process | PARP1, PARP2, ART3, ARF4, SIRT5, TNKS, ART4, SIRT4, ZC3HAV1, PARP14, TIPARP, SIRT2, PARP3, PARP16, TNKS2, PARP6, SIRT6, PARP8, ART5, PARP4, PARP10, ART1 |
| protein alpha-1,2-demannosylation | biological process | MAN1B1 |
| protein amidation | biological process | PAM |
| protein arginylation | biological process | LIAT1, ATE1 |
| protein auto-ADP-ribosylation | biological process | TNKS, PARP12, TIPARP, PARP3, PARP16, TNKS2, PARP6, PARP8, PARP11, PARP10 |
| protein autophosphorylation | biological process | EGFR, ERBB2, FLT1, FGFR2, FGFR3, AKT1, KDR, GSK3B, ATM, FGFR1, MTOR, INSR, YES1, IGF1R, KIT, SRC, ATR, LMTK2, MAK, CLK3, NTRK1, DDR1, CAMK4, MAPK14, CAMK2B, CAMK2D, WNK3, TRIM24, JAK2, GRK5, DYRK1A, EEF2K, ACVR1B, STK4, MARK2, MAP4K1, PEAK1, ALK, DYRK1B, IRAK1, UHMK1, PASK, EIF2AK1, STK25, STK17B, PTK2, PRKD1, BCR, FLT4, SYK, CLK2, MAPKAPK5, PRKX, HIPK4, ATP13A2, TAOK2, STK10, MKNK2, ZAP70, TEK, NTRK2, VRK2, ULK2, IRAK3, EPHB1, TAOK3, WNK2, ULK1, MELK, ULK3, SMG1, MAP3K3, MAP3K13, TAF1, MAP3K12, AAK1, HTATIP2, ERN1, CDKL5, EIF2S1, TNK1, CLK4, NLK, TNIK, ABL1, FER, TTK, CLK1, CSNK1G2, MAP3K9, SLK, STK26, LYN, TAOK1, NME2, EPHA4, EPHA1, DAPK1, MAP3K10, BTK, MAPKAPK3, FGR, EIF2AK2, MEX3B, MYO3A, SIK2, RIPK3, OXSR1, MOS, PDGFRB, PRKD2, CDK12, HCK, CDK5, MKNK1, RIOK2, DAPK2, THY1, PDGFRA, EPHA8, PIM2, FGFR4, CSK, MAPK15, GRK7, CAMKK2, NEK6, PDPK1, PRKCG, FES, CSF1R, INSRR, EPHB3, EPHB4, SIK1, PTK6, PIM3, CAD, GRK1, MINK1, AURKB, MYLK2, PTK2B, CAMK2A, TXK, NEK2, LRRK2, EIF2AK3, TYRO3 |
| protein autoprocessing | biological process | PARP1, FXN, OMA1, HTRA2, HJV, F12, TMPRSS2, PCSK2, AFG3L2, DHH, PIDD1, IHH, PCSK9, PISD, KLK6, MYRF |
| protein autoubiquitination | biological process | RAG1, BRCA1, UBE2B, RNF8, UBE2D3, UBE3A, TRIM17, ITCH, TRIM13, CNOT4, RNF183, LTN1, NFX1, DTX3L, TRIM37, RNF10, TRIM58, MARCHF7, DDB2, RNF41, PRKN, OBI1, TRIM68, STUB1, ERCC8, SH3RF1, KLHL24, SH3RF3, MARCHF5, RNF213, UHRF2, UBE2T, RNF187, RNF11, WWP2, RNF13, RNF19B, RCHY1, RNF157, TRAF6, SH3RF2, UHRF1, TRIM71, RNFT1, RNF141, RNF185, UBE4B, TRIM52, RNF181, RNF122, TRIM21, BFAR, RNF133, RNF146, RNF186, TRAF2, LRSAM1, RNF208, RAD18, AMFR, RNF115, UBE3D |
| protein biotinylation | biological process | HLCS |
| protein branching point deglutamylation | biological process | AGBL5 |
| protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan | biological process | DPY19L2, DPY19L1, DPY19L3, DPY19L4 |
| protein catabolic process | biological process | AKT1, UBR2, CTSD, MTOR, ELANE, PSMC2, SIAH1, TRIM24, PSMC6, CLPX, PPT1, USE1, BTRC, PGC, PSMC5, LONP2, IDE, CAPN3, CTRL, PSMC3, CLN8, UBR1, PJA1, BACE2, TPP1, PSMC4, CUL2, RNF165, MMP20, LNPEP, P2RX7, PSMC1, RBX1, BACE1, DIEXF, AMBP, PGA5, LONP1, TRAF2, LRSAM1, NAPSA, CLN6 |
| protein catabolic process in the vacuole | biological process | TCIRG1, CPA2 |
| protein catabolic process, modulating synaptic transmission | biological process | RNF216 |
| protein citrullination | biological process | PADI1, PADI2, PADI3, PADI4, PADI6 |
| protein complex assembly | biological process | TP53, FAS, SOX9, CDK1, CCNB1, MAPK3, MDM2, TGFBR3, HFE, WASL |
| protein complex localization | biological process | FKBP4, BIRC5, KIF17 |
| protein de-ADP-ribosylation | biological process | OARD1, MACROD2, ADPRH, ADPRHL1, MACROD1 |
| protein deacetylation | biological process | SIN3A, HDAC4, SIRT5, SIRT4, SIRT2, HDAC7, HDAC3, SIRT6, SIRT7, HDAC6, HDAC10, HDAC5 |
| protein deadenylylation | biological process | FICD |
| protein deglutamylation | biological process | AGBL2, AGBL4, AGBL5, AGBL1 |
| protein deglutarylation | biological process | SIRT5, SIRT7 |
| protein deglutathionylation | biological process | GLRX |
| protein deglycation | biological process | FN3K |
| protein deglycosylation | biological process | MGEA5, PARK7, MAN2B1, NGLY1, MAN2A1, MAN2A2, MAN2B2, AGA |
| protein delipidation | biological process | ATG4B |
| protein demalonylation | biological process | SIRT5 |
| protein demethylation | biological process | PHF2, PPME1, ALKBH4 |
| protein deneddylation | biological process | COPS5, COPS8, COPS6, COPS4, COPS2, COPS7B, GPS1, COPS7A |
| protein depalmitoleylation | biological process | NOTUM |
| protein depalmitoylation | biological process | PPT1, LYPLAL1, ABHD12, LYPLA1, ABHD17B, ABHD17A |
| protein dephosphorylation | biological process | BCL2, CDC25A, CDC25C, PTEN, CYCS, ACP1, PTPN11, DUSP6, SBF1, PTPRJ, PTPDC1, CDKN3, RNGTT, TPTE, PPP2R3A, MTM1, PPP2R5A, DUSP13, ILKAP, PPP1R12A, DUSP11, PPM1B, PPP2CA, PTPRR, MDP1, PPP4R1, DUSP22, MTMR6, PPP2R2A, DUSP8, DUSP19, DUSP15, CTTNBP2NL, DAPP1, BTRC, PPEF2, PTPRF, PPP2R1B, PPA2, MTMR4, PPP6C, PPP1R3D, PTPRA, PPP2R5C, PHLPP2, PTPN23, PHPT1, PPP3CB, PTPN2, PPP3CC, UBLCP1, PTPN6, TAB1, LRRC28, PPP1CB, PPM1L, LRRC8D, PTP4A1, LHPP, DUSP21, PTPRG, DUSP27, PPM1K, PPP1R3C, PTPRT, DUSP14, PPP2R5E, PTPN20, SDHAF2, PTPN22, PTPRC, PPP2R5D, DUSP5, PPM1J, MINPP1, PPEF1, PTPN13, SSH2, LRRC8C, PTPRB, PTPN9, DLG1, TIMM50, PPP4R2, CTDSP2, PPM1G, CDC14B, PTPRM, PPP3CA, PPP1R3B, PTPMT1, PTPRN2, PDP1, PP2D1, CTDSPL2, DUSP18, DUSP28, PPP4R3B, SSH3, PTPRU, PTPN1, PTPRE, PPM1A, CTDSPL, DNAJC6, DUSP1, PPP5C, PPP4C, MTMR3, CTDSP1, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, LRRC8B, PTPN5, PPP3R1, SSH1, EYA1, PDP2, PTPRS, PTPN14, PPM1E, PGAM5, CTDNEP1, LCK, PTPRZ1, PTPN12, CAMK2G, PTPN18, PTPRH, PTPN4, DUSP9, DUSP16, PHLPP1, MYH3, MYH |
| protein depolymerization | biological process | VPS4B |
| protein depropionylation | biological process | SIRT7 |
| protein destabilization | biological process | MDM2, CDKN2A, SRC, PRNP, IAPP, PEX2, SIAH1, SENP2, FBXW7, DERL1, BTRC, XBP1, SNCA, CHFR, PRKN, CREBBP, CAPN3, FBXO4, GGA3, CDC73, PLK1, FBXL3, EP300, MYLIP, PRKDC, RNF139, CCDC88C, IRGM, NR1D1, SIRT6, HDAC6, HTT, SERF2, BMP2, TRIM21, MUL1, DIEXF, KDM8, CTSH, ISOC2, PYHIN1, SERF1A, VPS35 |
| protein desuccinylation | biological process | SIRT5 |
| protein desumoylation | biological process | SENP2, SENP6, SENP5, SENP3, USPL1, SENP1, SENP7 |
| protein deubiquitination | biological process | USP9Y, USP1, USP26, USP8, SNX3, TADA3, PSMB1, PSMB5, PSMC2, ABRAXAS2, USP38, PSMA8, COPS5, USP47, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, KEAP1, USP13, TNIP3, UIMC1, PSMB7, IFIH1, EIF3F, OGT, CCP110, ACTL6A, USP14, PSMD6, ZC3H12A, WDR20, PSMD1, USP16, USP3, PSMD14, SIAH2, PSMD7, SMAD4, ASXL2, ASXL1, TAF9B, MAP3K7, PSMB6, RPS27A, USP32, STAMBPL1, SUDS3, PSMD10, PSMD8, PSMC5, DDB2, USP28, DESI2, USP29, PRKN, PSMB4, HCFC1, PSME1, TRAF3, HGS, MDM4, PSMB8, PSMD4, TAB1, INO80C, USP30, USP51, USP37, STAM, OTULINL, BABAM1, PSMC3, PSMA6, OTUD7A, UFD1, BABAM2, USP22, ADRB2, GATA3, NEDD8, ABRAXAS1, USP31, INO80B, USP53, NFKBIA, ATXN3, USP33, USP2, BIRC2, ADRM1, NFRKB, USP45, OTUB2, USP44, IKBKG, USP27X, STAM2, APC, YY1, EP300, SKP2, TOMM20, NLRP3, CYLD, MBD5, PSMD12, USP12, PSMB9, PSMC4, BECN1, MYSM1, USP36, RUVBL1, PSMD9, PSMA4, PSMD2, USP39, YOD1, USP7, TRAF6, UBC, TGFBR1, FOXK2, INO80D, USP48, RHOT1, WDR48, CLSPN, USP25, UBE2D1, UBA52, TAF10, USP4, SMAD2, PSMD5, RNF123, USP34, PSMF1, USP9X, SENP8, ZRANB1, PSMB3, TN |
| protein deubiquitination involved in ubiquitin-dependent protein catabolic process | biological process | OTUD7A, USP9X, ZRANB1, OTUD7B |
| protein export from nucleus | biological process | TGFB1, GSK3B, HSPA9, PKD1, ANKLE1, NUP88, XPO4, XPO1, ADAR, EIF5A, STRADB, AHCYL1, NXT1, RAN, DESI1, XPO7, CSE1L, STRADA, RANBP3, EGR2, XPO6, CHP1, TPR, CCHCR1, RANBP3L, NUTF2, CALR, NUP42, NUP214 |
| protein farnesylation | biological process | FNTA, FNTB, AIPL1 |
| protein folding | biological process | FKBP4, HSP90AA1, GNAO1, CSNK2A2, HSPA9, GNAI1, CSNK2B, PDIA3, TXNDC8, HSPD1, TXNDC2, FKBP6, HSPA8, CCT5, CCT4, FKBP5, CWC27, PPIL6, PPIL3, GRPEL1, PPIB, CANX, MLEC, PTGES3, DNAJA4, CCT7, AHSP, DNAJB11, CLPX, CCT6B, NGLY1, PFDN5, TTC1, DNAJA2, GNAI2, GNB3, ST13, CCT2, DERL1, LMAN2L, DNAJB4, CRYAB, P4HB, HSP90B1, TCP1, CCT6A, VBP1, PDCL, DNAJC21, DNAJC7, GNB5, DNAJC1, RUVBL2, BAG4, GNAI3, GNB1, PDIA6, GNB4, MKKS, BAG3, GNAZ, LMAN1, CCT3, RIC3, PFDN4, BAG5, QSOX1, PDIA4, GNAT2, TBCC, PDRG1, NKTR, PPID, QSOX2, NUDCD2, DNAJC19, ERO1A, DNAJC25, ERP27, CDC37L1, ZMYND10, CCT8, NFYC, MESD, TBCA, AHSA1, PRKCSH, PPIF, CSNK2A1, DNAJC4, GNG2, PPIG, SACS, PFDN1, ERP44, SIL1, DNAJB1, RANBP2, ERO1B, PFDN6, TRAP1, PPIH, TBCE, TBCD, PPIE, PSMC1, GNB2, FKBP8, RGS7, P3H1, NUDC, APCS, NPPC, PDIA5, NUDCD3, HSPE1, GRPEL2, PPIL2, MPDU1, CALR, PDIA2, LTBP4, RGS9, AMFR, RP2, PPIA, UBXN1, CDC37, PPIC |
| protein folding in endoplasmic reticulum | biological process | HSPA5, PDIA3, CANX, DNAJC10, HSP90B1, ERO1A, VAPA, DNAJC3, ERO1B, CALR, PDIA2 |
| protein geranylgeranylation | biological process | FNTA, CHML, RABGGTB, PGGT1B |
| protein glycosylation | biological process | MAN1B1, FUT4, GALNTL5, ST6GALNAC6, B4GALT2, ALG2, ALG5, B4GAT1, B3GALNT1, ST6GAL1, B3GAT1, SERP1, OGT, EXT1, EDEM3, RXYLT1, B4GALT4, GALNT2, MAN2A1, POMGNT2, SRD5A3, RPN2, FUT6, LARGE2, STT3B, ALG8, EXTL2, ALG10, TMTC2, B3GALNT2, MGAT4C, MGAT4A, B3GALT2, B3GLCT, EXTL1, DPAGT1, B4GALT3, RPN1, B3GALT6, LARGE1, STT3A, MAN2A2, ST6GALNAC4, MAN1A2, MPI, FUT5, GALNT13, NUS1, SDF2, MGAT5B, ALG10B, GALNT5, GCNT2, GALNT16, POFUT2, ENTPD5, DDOST, PSEN1, POGLUT3, TMTC1, GALNT4, ST8SIA2, ST8SIA4, ST6GAL2, FUT8, B3GAT2, ST6GALNAC2, OST4, TRIP11, GALNT10, GALNT15, MAGT1, B3GALT1, OSTC, B4GALT6, GCNT1, B3GNT5, B4GALT1, TMEM258, GALNT1, TMTC4, KRTCAP2, NPC1, C1GALT1, B3GALT5, B4GALT5, ST8SIA1, EXT2, ALG1, GALNT8, UGGT1, COG7, ST3GAL4, GALNT18, POGLUT1, GALNT11, POMGNT1, FUT9, DPM2, FUT7, COG3, NAGPA, DAD1, MGAT2, MAN1C1, POMT1, EXTL3, FKTN, FUT3, MAN1A1, GALNT12, ALG3, ST6GALNAC5, POFUT1, FKRP, ST6GALNAC1, B3GNT3, DPM1, ABO, B3GNT8, B3GNT4, MGAT4B, ST3GAL6, ST8SIA5, GOLGA2, FUT2, B3GNT6, GALNT9, B3GAT3, ST3GAL1, B3GNT9, GCNT7 |
| protein glycosylation in endoplasmic reticulum | biological process | ALG2, AQP11 |
| protein glycosylation in Golgi | biological process | FUT8, LMF1 |
| protein heterooligomerization | biological process | CASP8, CTNNB1, SEMG1, SEMG2, 39326, TMEM120A, SYT1, MAT2A, KCNC2, TMEM120B |
| protein heterotetramerization | biological process | INSR, ANXA2, HIST1H4A, NUDT21, RRM2, GRIN1, CBR4, HSD17B8, PKD2, CPSF7, RRM1, FARSB, GRIN2B, CPSF6, FARSA |
| protein heterotrimerization | biological process | COL1A2 |
| protein hexamerization | biological process | UGDH, LRRC8C, YME1L1, MAT2A, LETM1, SPAST |
| protein homooligomerization | biological process | FAS, BAX, VWF, HMOX1, POLQ, ACAT1, ANXA6, ANXA5, PRF1, RBMX, GOPC, PRNP, IAPP, FUS, CEP57, CHMP2A, ALS2, KCTD3, TNFAIP1, KCTD9, KCNA4, AQP11, KCTD13, KCND3, SHKBP1, ATL1, TMEM120A, MPP2, KCTD18, KCND2, NACC2, RNF135, KCND1, GLRA3, KCTD7, EHD4, UPB1, KCNG1, KCNG4, PRMT8, KCNC4, KCTD19, RNF213, KCNB1, ADCY8, ATL3, ECT2, PNPT1, TIFA, KCTD12, TRMT61B, G3BP2, ALAD, TP53BP1, PDCD6IP, BLM, KCNV1, PRMT1, KCTD10, KCNF1, KCNA6, KCTD17, KCNV2, KCNS3, KCNG2, KCTD1, CALHM1, KCTD15, KCTD5, PYCARD, KCNA2, KCTD8, EHD3, KCNC1, KCTD2, KCNC2, KCTD14, ATL2, MICU1, LETM1, KCNA3, KCNA1, KCTD11, TRIM72, GSDMD, KCNC3, KCNG3, SPAST, RIPOR2, ZBTB1 |
| protein homotetramerization | biological process | SOD2, DECR1, CAT, APOA1BP, DNM1L, TP63, THG1L, DCXR, AQP2, PFKM, SHMT1, USP16, ALDH9A1, PFKP, GNMT, VASP, CRTC3, RYR1, CBR4, GBP5, PKD2, OSBPL2, ACOT13, PKD2L1, TRPA1, ALDH1A3, APIP, UPB1, CBY1, ALDOA, SHMT2, EVL, SAMHD1, CRYZ, HPRT1, CTH, APPL2, HSD17B10, KCNJ2, ACACA, HCN1, PFKL, TRPM4, GLS, AQP10, ACACB, MAT1A, GOLGA2, KCNJ12, CRTC1, MCOLN1, KIF25, TRPM2, TK1, TRPV1 |
| protein homotrimerization | biological process | MGST1, MIF, ALOX5AP, ASIC1, SLC1A5, SLC1A2, STEAP4, PNPT1, ITLN1, SCARA5, SIGMAR1, P2RX3, CLYBL |
| protein hydroxylation | biological process | P3H1, OGFOD1, JMJD4 |
| protein import | biological process | APOE, CLU, GPIHBP1, LAMP2, SNX33 |
| protein import into mitochondrial intermembrane space | biological process | AIFM1 |
| protein import into mitochondrial matrix | biological process | TIMM21, GRPEL1, DNAJC15, DNAJC19, TOMM7, TOMM20, TIMM50, TIMM17B, TIMM17A, TIMM44, TOMM20L, GRPEL2, PAM16, TOMM40 |
| protein import into mitochondrial outer membrane | biological process | HSP90AA1, HSPA4, TOMM22, SAMM50 |
| protein import into nucleus | biological process | STAT3, PDIA3, FGF9, KPNA4, NUP93, KPNA2, HIKESHI, NUP88, NUP85, NUP107, POM121, TXNIP, IPO11, KPNA5, PIK3R1, PTTG1IP, ABRA, NPAP1, ADAR, IPO9, NUP50, NUP62, IPO4, KPNA3, IPO8, KPNA6, SYK, MBTPS1, NUP155, NUP153, TMCO6, IPO5, E2F3, PHB2, TNPO3, NFKBIA, POM121L2, NXT1, RAN, NUP133, TNPO1, SIX3, CSE1L, PPP3CA, HEATR3, IPO7, PML, KPNA1, NXT2, SNUPN, TPR, NUP98, CDKN1A, FAM53B, APPL2, SIX2, RANBP6, FAM53C, IPO13, DRD1, ARNTL, NUTF2, TSC2, PPP1R10, APPL1, PRICKLE1, TNPO2, AGT, NUP188, FAM53A, NUP214, SPRN, LRRK2, TP53 |
| protein import into nucleus, translocation | biological process | TGFB1, TNF, IFNG, AKT1, AKR1C3 |
| protein import into peroxisome matrix | biological process | PEX10, PEX7, PEX2, LONP2, PEX26, PEX5, PEX12, PEX14, PEX1, PEX16 |
| protein import into peroxisome matrix, docking | biological process | PEX5, PEX13, PEX5L, PEX14 |
| protein import into peroxisome matrix, substrate release | biological process | PEX14 |
| protein import into peroxisome matrix, translocation | biological process | PEX5, PEX14 |
| protein import into peroxisome membrane | biological process | PEX19, PEX26, RAB8B, PEX5, PEX3, PEX16 |
| protein initiator methionine removal | biological process | METAP2, METAP1D, METAP1 |
| protein insertion into ER membrane | biological process | GET3, TRAM2, GET4 |
| protein insertion into membrane | biological process | EGFR, RTP5, REEP1, COX18, RTP3, OXA1L, GRIN3B, RTP1 |
| protein insertion into mitochondrial inner membrane | biological process | TIMM9, TIMM13, TIMM29, TIMM10, AGK |
| protein insertion into mitochondrial inner membrane from matrix | biological process | MAIP1, BCS1L, COX18, OXA1L |
| protein insertion into mitochondrial membrane | biological process | MAIP1, TOMM22, COX18 |
| protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological process | BAX, BAD, BCL2L11, BMF, MOAP1 |
| protein insertion into plasma membrane | biological process | MAL |
| protein K11-linked deubiquitination | biological process | USP30, USP37, OTUD7A, OTUB2, YOD1, OTUD6A, OTUD7B, OTUD3 |
| protein K11-linked ubiquitination | biological process | UBE2B, UBE2D3, UBE2W, RNF26, CDC16, CDC23, FZR1, ANAPC5, PRKN, UBE2H, UBE2E3, UBE2D4, ANAPC7, UBE2L3, UBE2T, ANAPC11, UBE2E2, ANAPC13, CDC27, CDC26, ANAPC1, UBE2C, ANAPC4, ANAPC2, UBE2S |
| protein K27-linked deubiquitination | biological process | YOD1, OTUD6A, OTUD3 |
| protein K27-linked ubiquitination | biological process | PRKN, RNF6, UBE2D4, UBE2T, UBE2S |
| protein K29-linked deubiquitination | biological process | USP13, YOD1, ZRANB1, OTUD6A |
| protein K29-linked ubiquitination | biological process | ITCH, PRKN, UBE2D4, UBE2T, RNF186, UBE2S |
| protein K33-linked deubiquitination | biological process | YOD1, ZRANB1, OTUD6A |
| protein K33-linked ubiquitination | biological process | KLHL20 |
| protein K48-linked deubiquitination | biological process | USP8, USP13, MINDY4, MINDY1, MINDY3, DESI2, USP37, OTUD7A, ATXN3, USP33, OTUB2, USP27X, CYLD, MINDY2, YOD1, USP7, USP25, USP34, USP9X, USP15, OTUD5, OTUD4, OTUD7B, USP20, BAP1, OTUD3, USP5 |
| protein K48-linked ubiquitination | biological process | UBE2B, RNF8, TTC3, UBE2D3, UBE3A, FBXO38, RNF34, UBR5, ITCH, UBE2R2, DTX3L, UBE2Q2, PELI1, UBE2G1, ARIH2, PRKN, UBE2H, UBE2E3, RNF6, UBE2D4, SKP2, UBE2T, TRIM38, RNF187, UBE2E2, NEDD4L, IFI27, HACE1, CDC34, RNF126, UBE2D1, UBE2E1, UBE2K, SYVN1, MARCHF6, UBE2C, ZNRF1, BFAR, RNF152, RNF146, RNF216, TOPORS, AMFR, RNF115 |
| protein K6-linked deubiquitination | biological process | USP13, USP30, OTUD3 |
| protein K6-linked ubiquitination | biological process | BRCA1, PRKN, RNF6, UBE2D4, UBE2T, BARD1, UBE2S |
| protein K63-linked deubiquitination | biological process | USP8, ABRAXAS2, USP13, PSMD14, STAMBPL1, DESI2, BABAM1, OTUD7A, BABAM2, ABRAXAS1, ATXN3, USP33, SHMT2, OTUB2, USP27X, CYLD, YOD1, USP7, USP25, ZRANB1, OTUD5, STAMBP, OTUD4, OTUD7B, USP20, OTUD1 |
| protein K63-linked ubiquitination | biological process | UBE2B, CDKN2A, RNF8, ITCH, RNF168, ZFP91, MAGEL2, PRPF19, PELI1, UBE2N, UBE2G1, ARIH2, PRKN, TRAF3, UBE2NL, STUB1, UBE2E3, UBE2D4, RNF135, NEDD4, UBE2V1, UBE2T, UBE2E2, WWP2, TRAF6, UBE2V2, RNF126, PELI3, TRAF4, TRAF5, BFAR, RNF152, TRAF1, RNF186, TRAF2, TRIM56, UBE2O, HECTD1, RNF115, UBE2S, TRIM5 |
| protein K69-linked ufmylation | biological process | UBA5, UFM1, UFC1, DDRGK1 |
| protein kinase A signaling | biological process | EZR, FBN1, PRKACB, TTN, MROH2B, PRKACG, RDX, LCP1, GAL, MYOM1 |
| protein kinase B signaling | biological process | TGFB1, TNF, IL1B, SOX9, AXL, AKT1, GAS6, PTEN, IGF1, CCL5, PIK3CA, RPS6KB2, NKX3-1, CCL3, SETX, SIRT2, P2RY12, SMPD3, ADTRP, LOX, THEM4, PIK3R3, ZFP36L1, TMEM100, PIK3C2B, MT3, ILK, EPHA2, PLK3, TSC2, SESN2, PEAR1, CD40, MERTK, CCL2, TYRO3 |
| protein kinase C deactivation | biological process | EDN1 |
| protein kinase C signaling | biological process | MAS1, PDGFB, PLEK, FLOT1, CSRP3, PRKCZ, AVP, AZU1, DGKQ, PLVAP, SLC26A6, ANKRD1, HTR2B |
| protein kinase C-activating G-protein coupled receptor signaling pathway | biological process | EDNRA, IL2, F2R, PICK1, DGKK, CISH, DGKE, DGKB, PLPP1, DGKI, DGKA, DGKG, DGKZ, PARD3, PRKD3, DGKH, LRP1, HTR1B, HCRT, EDN1, CCK, AZU1, CHRM1, ADORA2A, DGKQ, DGKD, BDKRB1, GAP43, HTR2B |
| protein kinase D signaling | biological process | PRKD1, PRKD3, PRKD2 |
| protein linear deubiquitination | biological process | OTULIN, CYLD |
| protein linear polyubiquitination | biological process | SHARPIN, RBCK1, RNF31 |
| protein lipidation | biological process | ATG10, PIK3C3, WDR45, WIPI2, WDR45B, WIPI1, ALOX12B, UGCG |
| protein lipidation involved in autophagosome assembly | biological process | ATG5, WIPI2, IRGM |
| protein lipoylation | biological process | NNAT, GLRX5, GCSH, LIPT1, LIAS, NDUFAB1 |
| protein localization | biological process | TP53, NR0B1, AKAP4, MLH3, KIF26B, TRAK2, NPM1, BBS2, ALS2, BCL6, TNS4, NIN, WNK4, CD81, KIFAP3, MAPRE3, DHCR24, SLC9A2, CACNG3, IST1, RAB35, PARD3B, NEDD8, BBS4, CAV3, SCRIB, NRCAM, TRAK1, CBY1, GRIP1, ULK1, SQSTM1, PARD3, GNGT1, MECP2, DLG1, AMN, HEATR5B, AP4S1, CUTA, ODR4, CEP128, EXOC8, SPTSSA, AKAP10, MAPRE1, DUOXA2, AP4M1, DDX42, CEP250, GGA1, AP4B1, PLOD3, PALM, AKAP11, DUOXA1, TSC2, CCDC68, CADM3, LRP4, DRD2, CROCC, PHYHIP, BIN3, MGAT3, DOC2B, NBEA, LRRC61, AKAIN1, HAP1, AP4E1, CAV1, HEATR5A |
| protein localization involved in establishment of planar polarity | biological process | CELSR1 |
| protein localization to actin cytoskeleton | biological process | PPP1R9B |
| protein localization to adherens junction | biological process | TJP1, DLG5, MPP7, SCRIB |
| protein localization to axon | biological process | ANK3, COPA, TRIM46 |
| protein localization to basolateral plasma membrane | biological process | LIN7C, LIN7A, AP4M1, LIN7B, CAV1 |
| protein localization to bicellular tight junction | biological process | TJP1, ACTG1, F11R, CDH5, ACTN4 |
| protein localization to Cajal body | biological process | WRAP53 |
| protein localization to cell cortex | biological process | EZR, NUBP1 |
| protein localization to cell junction | biological process | LAMTOR3, MARVELD3, JAM3, NECTIN1 |
| protein localization to cell leading edge | biological process | CORO1B, COPA |
| protein localization to cell periphery | biological process | PPP1R9B, KIF1B |
| protein localization to cell surface | biological process | CTNNB1, AP3B1, JAM3, RIC3, GPIHBP1, FBLN5, EMP2, GGA3, MESD, ANGPT1, ANK2, FCN1, VCL, PTPRU, USP4, WNT11, ARF6, GGA2, GGA1, FGF7, PIGK, PIGU, FGF10 |
| protein localization to cell-cell junction | biological process | TJP1, CGNL1, DSP, JAK1, ARHGEF18 |
| protein localization to centrosome | biological process | PCM1, CCDC14, NEDD1, SNX10, HOOK3, DISC1, CEP131, KIAA0753, MCPH1, PIBF1, BBS4, CSNK1D, C2CD3, DCTN2, STIL, CEP192, CEP83 |
| protein localization to chromatin | biological process | ESR1, EZH2, MCM8, CARM1, WAPL, MCM9, LEMD2, PLK1, RAD21, CHMP7, MRNIP |
| protein localization to chromosome | biological process | SPO11, TEX15, RPA2, RPA1, TTK |
| protein localization to chromosome, centromeric region | biological process | RB1, BOD1, CENPA |
| protein localization to chromosome, telomeric region | biological process | ATR, TERF2IP, XRCC5, ATRX, TNKS, TINF2, TNKS2, TPP1, ACD, PINX1 |
| protein localization to ciliary membrane | biological process | WDR19, RABEP1, RAB29, ARL3, GGA1 |
| protein localization to ciliary transition zone | biological process | TCTN2, TCTN1, CPLANE1, TMEM107, MAPK15, CC2D2A |
| protein localization to cilium | biological process | ARF4, LRRC6, DZIP1, TTC21A, ATP6V1D, TTC26, TULP3, SNX10, TULP1, WDR35, ARL3, BBS9, ARL6, TULP2, BBS4, CSNK1D, TTC21B, DZIP1L, ZMYND10, ROPN1B, TBC1D32, IFT122, ZNF423, RAB11FIP3, BBS1, TUB |
| protein localization to cytoplasmic stress granule | biological process | DDX1, DDX3X, SSB, TIA1, YBX1, DCP1A |
| protein localization to cytoskeleton | biological process | FAM83H |
| protein localization to cytosolic proteasome complex involved in ERAD pathway | biological process | BAG6, ATXN3 |
| protein localization to early endosome | biological process | NRP1 |
| protein localization to endoplasmic reticulum | biological process | UBAC2, VAPA, ANK2, PPP1R15A |
| protein localization to endoplasmic reticulum exit site | biological process | SEC16A, BCAP31, MIA3, BCAP29, GBF1, LRRK2, SEC16B |
| protein localization to endoplasmic reticulum tubular network | biological process | GBF1 |
| protein localization to endosome | biological process | WASHC2A, RAB35, PACSIN2, TOLLIP, TMEM30A, ARF6, AKAP11, MICALL1, VPS35, WASHC2C |
| protein localization to Golgi apparatus | biological process | OPTN, PACS1, RAB6A, GBP5, CSNK1D, PAQR3, ARL1, BICD2, OBSL1, GCC2, SORL1, GAK, RAB33B, COG7, GBF1, ARFRP1, RIPOR1 |
| protein localization to Golgi membrane | biological process | ARL5B, ARL5A |
| protein localization to heterochromatin | biological process | TASOR, PPHLN1 |
| protein localization to juxtaparanode region of axon | biological process | EPB41L3, CNTN2, CNTNAP2, NFASC, CNTNAP1 |
| protein localization to kinetochore | biological process | CDK1, IK, MIS12, ZW10, BUB3, SPDL1, TTK, MTBP, AURKB |
| protein localization to kinetochore involved in kinetochore assembly | biological process | CENPT |
| protein localization to lipid droplet | biological process | AUP1 |
| protein localization to lysosome | biological process | SH3BP4, RTN4, LAMTOR5, CD81, ATP13A2, GGA3, C12orf66, SZT2, RNF128, KPTN |
| protein localization to M-band | biological process | ANK2, OBSCN |
| protein localization to meiotic spindle midzone | biological process | TTK |
| protein localization to membrane | biological process | TM9SF3, FERMT2, RAB29, RAB38, TM9SF2, AP3D1, HGS, CAPN3, RAB32, STX1B, TM9SF4, TIAM1, CPE, TM9SF1, SH3PXD2B, ABHD17A, PACSIN1, AGER |
| protein localization to membrane raft | biological process | FLOT1, RFTN1, CYP46A1 |
| protein localization to microtubule | biological process | GSK3B, MAPRE3, DVL1, DIAPH1, KIF20B, CRIPT, MAPRE1, MID2, MID1 |
| protein localization to microtubule plus-end | biological process | MAPRE3, GAS2L1, MAPRE1, GAS2L2 |
| protein localization to microvillus | biological process | USH1C |
| protein localization to mitochondrion | biological process | DNM1L, PRKN, MARCHF5, RNF186, LRRK2 |
| protein localization to mitotic actomyosin contractile ring | biological process | ANLN, RTKN |
| protein localization to mitotic spindle | biological process | FAM83D |
| protein localization to mitotic spindle pole body | biological process | WRAP73 |
| protein localization to non-motile cilium | biological process | ARL6, TTC21B |
| protein localization to nuclear envelope | biological process | TOR1AIP1, PLK1, TOR1AIP2, TMEM201 |
| protein localization to nuclear inner membrane | biological process | NUP155, NUP54 |
| protein localization to nuclear pore | biological process | SUMO1, OSBPL8, NUTF2 |
| protein localization to nucleolus | biological process | RPF2, NOL8, RAN, RRS1, PINX1 |
| protein localization to nucleoplasm | biological process | TBRG1 |
| protein localization to nucleus | biological process | SOX9, MDM2, BMP7, BMP4, SHH, PLRG1, TOR1AIP1, CNEP1R1, RPL11, PIKFYVE, XPO1, DVL1, PAF1, MSX1, GBP2, SMO, YWHAE, PYGO1, SIX1, TOR1B, BANP, SIX4, CTDNEP1, ZBTB16, ZBTB7A, HHEX, ABCA7, CALR, TOPORS |
| protein localization to organelle | biological process | PCM1, DZIP1, BBS2, RAB3IP, AP3D1, BICD1, BBS4, DZIP1L, PLK1, ANK2, CSRP3, BICD2, COG7, CEP68, CEP250, COG3, PES1, TCIRG1, ARFRP1, CNGB1, CROCC, VPS35 |
| protein localization to paranode region of axon | biological process | EPB41L3, NFASC, MAL, CNTNAP1, UGT8 |
| protein localization to pericentriolar material | biological process | GOLGB1, NUDCD3 |
| protein localization to perinuclear region of cytoplasm | biological process | RNF26, SQSTM1 |
| protein localization to phagophore assembly site | biological process | PIK3C3, STX17, WDR45, WIPI2, MFN2, WDR45B, ATG9A, WIPI1, TRAPPC8, PACS2, ATG13, ATG9B |
| protein localization to photoreceptor connecting cilium | biological process | SPATA7 |
| protein localization to photoreceptor outer segment | biological process | TULP1, PCARE, BBS4, ZDHHC3, TUB, SPATA7 |
| protein localization to plasma membrane | biological process | DPP6, CDH1, WNK3, SCP2, RAB11A, EFR3A, PACS1, RAB40A, ANK3, RAPGEF2, SEC16A, CD81, C2CD5, FAM126A, SLC9A3R1, ABCA12, RAB3C, DCHS1, EPB41L3, ROCK2, BAG4, RAPGEF6, RAMP2, SPTBN1, ADIPOQ, ZDHHC23, RAB8B, MRAP2, RAB40B, KCNIP4, MYO5A, EMP2, PIP5K1A, ACTN2, CAV3, RAB15, ROCK1, TMED2, EHD4, LRP6, RAB3B, SKAP1, PRAM1, TTC7A, ITGB1BP1, FLOT1, ANK2, DLG1, KCNB1, SLMAP, SEC23A, FYB2, RAB40C, INPP5K, TNIK, EXOC5, FYB1, FCHO2, DENND4C, SYTL2, F11R, NFASC, RDX, PRKCZ, MYADM, ZDHHC3, ZDHHC2, EFR3B, TSPAN15, GPR158, TESC, GAK, PKP2, IKBKB, RAMP3, ATP1B1, P2RY1, EHD2, CLASP2, PALM, EPHA2, FCER1G, PIGW, TMEM150A, RAP2A, JUP, TSPAN14, EHD3, S100A10, RAB8A, RAB34, LAMA5, RAMP1, RAB3D, CACNB3, ATP1B3, NKD2, PKP3, AKT2, PPIL2, PTCH1, PACS2, KCNIP3, ATP2C2, SLC4A1, ZDHHC22, PLEKHF1, CRB3, SPTBN4, TSPAN5, WDR72, TTC7B, TRARG1, FAM126B, PACSIN1, RAB40AL, CACNB2, SCN3B, TNF |
| protein localization to plasma membrane raft | biological process | CAV1 |
| protein localization to postsynaptic membrane | biological process | GRIN1, GRIN2C, ZDHHC2, GRIN2A |
| protein localization to secretory granule | biological process | SCG3, CPE |
| protein localization to site of double-strand break | biological process | SLF2, PARP3, SLF1 |
| protein localization to spindle microtubule | biological process | HNRNPU |
| protein localization to synapse | biological process | BAIAP2, ASIC2, NRXN1, LRRTM1, NLGN2, BSN, DLG4, CDK5, NPHS1, SHANK1, RELN, MPP4 |
| protein localization to T-tubule | biological process | ANK2, ASB3 |
| protein localization to tricellular tight junction | biological process | LSR, MAPK9 |
| protein localization to vacuolar membrane | biological process | SH3GLB1 |
| protein localization to vacuole | biological process | GBP1 |
| protein mannosylation | biological process | NUS1, DPM1 |
| protein maturation | biological process | HSPD1, ISCA2, LMF2, DNAJB11, SNAPIN, STUB1, PSEN1, TSPAN15, SORL1, TESC, DUOXA2, TSPAN14, TASP1, LMF1, TSPAN5, SERPINH1 |
| protein maturation by copper ion transfer | biological process | ATP7B |
| protein maturation by iron-sulfur cluster transfer | biological process | ISCA2, ISCA1, NFU1, CIAO2A, CIAO1, CIAO2B, GLRX3, MAGEF1, MMS19, HSCB, BOLA2 |
| protein maturation by protein folding | biological process | PRDX4, WFS1, AIP, ERO1A, FKBP1B, ERO1B, CALR |
| protein maturation by [2Fe-2S] cluster transfer | biological process | CISD3 |
| protein maturation by [4Fe-4S] cluster transfer | biological process | ISCA2, CIAO2A, CIAO2B, YAE1, LTO1 |
| protein metabolic process | biological process | PAM, NUMBL, LAP3, PRKN, MMP16, ACACA, NECAB3, NPEPL1 |
| protein methylation | biological process | PRMT6, PCMT1, GSPT1, ETF1, CARM1, METTL21C, EEF1AKMT1, FAM98A, METTL21A, PRMT2, SNRPB, BTG2, PRMT8, FAM98B, EEF2KMT, PCMTD1, LCMT1, ARMT1, METTL22, VCPKMT, PCMTD2, ETFBKMT, PRMT1, CAMKMT, HEMK1, PRMT3, EEF1AKMT2, PRMT7 |
| protein modification by small protein conjugation | biological process | ATG10, MOCS3, NAE1, UBD, UBA7, UBA2, UBA3, UBA5, UBA6, SAE1 |
| protein modification by small protein removal | biological process | SENP6, DESI2, DESI1 |
| protein modification process | biological process | PARP1 |
| protein mono-ADP-ribosylation | biological process | PARP12, PARP14, TIPARP, PARP3, PARP16, PARP6, PARP8, PARP4, PARP11, PARP10 |
| protein monoubiquitination | biological process | UBE2B, UBE2D3, UBE2W, TSG101, TRIM25, UBE2R2, HUWE1, MARCHF7, NEURL1, KLHL22, DTL, PRKN, CUL1, OBI1, KLHL12, FANCL, MGRN1, NEDD4, PEX12, UBE2T, NEDD4L, CBL, KLHL21, RNF126, UBE4B, RBX1, TRIM21, KBTBD8, FBXL2, UBE2O, ZNF598, TOPORS, RAD18, UBE3D |
| protein N-linked glycosylation | biological process | ALG5, B3GALNT1, PGM3, GFPT1, TMEM165, RPN2, STT3B, ALG8, ALG10, MGAT4C, MGAT4A, B3GALT2, DPAGT1, RPN1, STT3A, PMM1, GORASP1, MGAT5B, ALG10B, ENTPD5, DDOST, FUT8, SLC39A8, MAGT1, B3GALT1, B4GALT1, TMEM258, KRTCAP2, B3GALT5, DAD1, MGAT2, MAN1C1, MGAT4B, ST3GAL1, MGAT3, MGAT4D |
| protein N-linked glycosylation via arginine | biological process | KRTCAP2 |
| protein N-linked glycosylation via asparagine | biological process | ST6GALNAC6, ALG5, ST6GAL1, RPN2, STT3B, ALG8, MCFD2, RPN1, LMAN1, ASGR2, STT3A, DDOST, FUT8, OST4, MAGT1, OSTC, UGGT1, DPM2, DAD1, MGAT2, DPM1, B4GALNT2, DERL3, UGGT2, ASGR1 |
| protein neddylation | biological process | DCUN1D1, DCUN1D4, NAE1, DCUN1D5, NEDD8, TRIM40, UBA3, UBE2F, UBE2M, RBX1, DCUN1D2 |
| protein O-GlcNAcylation via threonine | biological process | EOGT |
| protein O-linked fucosylation | biological process | ADAMTS5, B3GLCT, POFUT2, MFNG, SLC35C1, POFUT1, LFNG |
| protein O-linked glycosylation | biological process | B4GAT1, TRAK2, B3GALNT1, OGT, PGM3, GALNT2, POMGNT2, LARGE2, B3GALNT2, B3GALT2, B3GALT6, LARGE1, PLOD2, GALNT13, TRAK1, ST6GALNAC2, GALNT10, C1GALT1C1, B3GALT1, TET3, B3GNT5, GALNT1, TET1, C1GALT1, B3GALT5, GALNT18, POGLUT1, POMGNT1, POMK, PLOD3, VEGFB, POMT1, FKTN, EOGT, TET2, POFUT1, B3GNT3, B3GNT8, B3GNT4, B3GNT6, GALNT9, B3GNT9, B3GNT7, GALNT7 |
| protein O-linked glycosylation via serine | biological process | GALNT2, GALNT13, MGAT5B, GALNT16, POGLUT3, GALNT4, GALNT1, POGLUT1 |
| protein O-linked glycosylation via threonine | biological process | GALNT2, GALNT13, GALNT16, GALNT4, GALNT1, GALNT11, GALNTL6 |
| protein O-linked mannosylation | biological process | B4GAT1, RXYLT1, POMGNT2, LARGE2, TMTC2, SDF2L1, LARGE1, SDF2, TMTC1, TMTC4, DPM2, POMT1, FKTN, FKRP, DPM1, CRPPA |
| protein oligomerization | biological process | AR, BAX, EPPIN, GJA1, MALT1, ZC3H12A, OAS1, WDCP, SLC9A1, STOML2, OPA1, HGSNAT, ADCY8, CHP1, ZNHIT6, BOK, BLM, STING1, NOL3, CLDN1, HSCB |
| protein oxidation | biological process | GPX1, APOA1, LOX, SUMF1 |
| protein palmitoylation | biological process | ZDHHC16, ZDHHC8, ZDHHC5, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC23, GLUL, HHAT, ZDHHC21, ABHD17B, ZDHHC20, ZDHHC3, ZDHHC2, ZDHHC13, ZDHHC7, ZDHHC22, ZDHHC12, ABHD17A, ZDHHC18, ZDHHC1 |
| protein peptidyl-prolyl isomerization | biological process | FKBP4, FKBPL, FKBP6, FKBP5, CWC27, PPIL6, PPIL4, PPIL3, PPIB, FKBP14, PIN1, AIP, FKBP7, FKBP10, FKBP3, NKTR, PPID, PPIF, PPIG, FKBP1B, FKBP11, PIN4, RANBP2, PPWD1, PPIH, FKBP2, PPIE, FKBP8, AIPL1, PPIL2, PPIA, PPIC |
| protein phosphorylation | biological process | EGFR, TGFB1, AMHR2, TSSK4, TSSK6, AURKC, BIRC5, ERBB2, CDK1, CCNB1, FLT1, ERCC2, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, KDR, GSK3B, HSF1, ATM, GAS6, APP, FGFR1, CSNK2A2, MTOR, CSNK2B, BRSK2, INSR, YES1, IGF1R, KIT, SRC, PIK3CA, MAPK8, BMPR2, LMTK2, CDC7, RAF1, MAK, CLK3, CDK9, LIPE, PICK1, NTRK1, DDR1, CAMK4, MAST2, LIMK2, DMPK, MAPK14, RYK, ROR1, CAMK2B, CAMK2D, PDK4, PAN3, WNK3, TBK1, NRBP1, MOK, TRIM24, JAK2, GRK5, CSNK1A1, STK3, DYRK1A, NEK8, COPS8, STK36, PLK2, MAP3K4, EEF2K, DYRK3, KALRN, MARK3, CDK7, CCL8, MAP4K2, MAPK6, COQ8A, PPP4R1, PHKB, NEK1, TRIB3, RPS6KB2, ATP23, CIT, FAM20B, CPNE3, CDK14, PIK3R1, ACVR1B, STK4, PTK7, MAPK11, MARK2, ADCK2, MAP4K1, WNK4, PPP1R9B, STK31, EIF2A, PEAK1, ALK, DYRK1B, PRKAB1, MAP3K7, CCNT1, PRKRA, PDGFB, RPS6KB1, PRKCH, LTK, MAPK4, CSNK1E, IRAK1, TLK2, UHMK1, TBCK, NPRL2, COQ8B, ALPK1, PASK, EIF2AK1, MAP3K20, STK17A, RPS6KL1, STK25, IRAK2, BUB1, BUB1B, STK17B, PTPRA, PRKACB, EPHB2, TIE1, ACVR1, PTK2, MORC3, PRKD1, STK38, CAMK1D, MASTL, CDK15, PRKAG2, ROCK2, |
| protein poly-ADP-ribosylation | biological process | PARP1, TNKS, ZC3HAV1, PARP14, PARP3, TNKS2, PARP10 |
| protein polyglutamylation | biological process | CEP41, TTLL7, TPGS1, TTLL1, TTLL6, TTLL2, TTLL4, TTLL11, TTLL9, TPGS2, CFAP20 |
| protein polymerization | biological process | CHMP2A, CHMP4A, MID1IP1, CASQ2, FGG, CHMP4B, ARL6, FGB, VTN, FGA, CASQ1, CHMP3, NEFL |
| protein polyubiquitination | biological process | BCL2, UBE2B, UBR2, CDKN2A, RNF114, PSMA3, PSMB1, PSMB5, PSMC2, UBE2D3, RNF20, TRIM69, SIAH1, PSMA8, UBE2W, HECW2, MKRN1, PSMA7, UBR5, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, UBE4A, TRIP12, UBE3C, FBXO11, ZNRF2, ITCH, PSMB7, DDA1, SKP1, BLMH, PSMD6, FBXO15, RNF183, PSMD1, RNF19A, FBXL5, PRPF19, PSMD14, SIAH2, PSMD7, LONRF1, FBXL22, UBE3B, HUWE1, DTX3L, UBE2Q2, FBXW7, FBXO17, PELI1, AKTIP, FBXL12, RNF14, BTRC, ARIH1, PSMB6, UBE2N, UBE2G1, RPS27A, RNF144B, FBXL13, TRIM58, FBXO9, TRIM3, PSMD10, TNKS, ARIH2, PSMD8, NPEPPS, PSMC5, RBBP6, UBE2Q1, DZIP3, DDB2, CHFR, TRIM2, RNF41, DTL, FBXO2, PRKN, PSMB4, UBE2H, PSME1, CUL1, UBE2NL, RNF217, RNF167, ANKIB1, PSMB8, PSMD4, CBFB, RMND5A, FBXO4, STUB1, PSMC3, PSMA6, ERCC8, FBXO30, UBE2E3, C10orf90, FBXO10, FBXL4, UBE2D4, THOP1, TRIM32, RNF135, FBXO32, PELI2, WSB1, MGRN1, NEDD4, UBE2U, RC3H2, MARCHF5, FBXL16, BIRC2, FBXW10, RNF213, TNKS2, RLIM, FBXL17, FBXL3, SPOP, TAF1, UBE2L3, SKP2, UBE2V1, MYLIP, UBE2T, FBXO40, TMEM129, PSMD12, TRIM38, PSMB9, PSMC4, RC3H1, RNF165, FBXO22, UBE |
| protein prenylation | biological process | FNTA, RABGGTB, PGGT1B, PTAR1, FNTB |
| protein processing | biological process | CASP1, CASP3, DYNC2H1, CPN1, GLI3, CPM, METAP2, OGT, CPZ, CPXM2, APH1B, PSENEN, ZMPSTE24, ECE1, LONP2, APH1A, F7, CPXM1, PIK3C3, F12, CASP2, PSEN1, PCSK2, PCSK6, MMP16, PCSK4, CPD, SRGN, C2CD3, AFG3L2, MMP14, SDE2, XPNPEP3, ADAMTS2, KLK13, CTSS, CLN3, ASPRV1, P2RX7, CPE, PCSK1, AEBP1, PSEN2, FKRP, FURIN, COMP, ADAMTS13, PTCH1, PCSK9, PCSK7, ADAMTS3, IFT172 |
| protein processing involved in protein targeting to mitochondrion | biological process | PMPCB, UQCRC2, IMMP1L, PMPCA, IMMP2L, MIPEP |
| protein quality control for misfolded or incompletely synthesized proteins | biological process | UBE2W, NGLY1, CLPP, OMA1, ZER1, LONP2, ZYG11B, STUB1, ATXN3, FBXL17, YME1L1, HDAC6, LONP1 |
| protein refolding | biological process | HSP90AA1, HSPA2, B2M, HSPA1A, HSPA1B, HSPD1, HSPA1L, HSPA8, DNAJA4, HSPA14, DNAJA2, HSPA13, FKBP1B, HSPA6, CRYAA, DNAJB2 |
| protein repair | biological process | PCMT1, MSRB3, MSRA, MSRB2, MSRB1 |
| protein retention in ER lumen | biological process | PDIA3, KDELR2, KDELR3, ANKRD13C, GRIK5, RER1, GPAA1, OS9, KDELR1, PDIA2 |
| protein retention in Golgi apparatus | biological process | VPS13C, VPS13D, GOLPH3, SORL1 |
| protein secretion | biological process | GNAS, LTBP2, CANX, RAB3C, CBLN4, FGG, RAB8B, PSAP, PDIA4, RAB15, RAB3B, COPG1, GOLPH3, TVP23B, SEL1L, CTAGE8, CTAGE4, ARFGAP3, MIA3, TMEM167A, SVBP, SCG2, CTAGE1, ARL4D, MON1A, C1QTNF5, STEAP3, COPG2, RAB8A, RAB3D, COMP, TANGO2, NECAB3, PREB, CAVIN1, OLFM2, LMF1, TVP23C, MTTP, TANGO6, SNCG |
| protein secretion by platelet | biological process | PLEK, DMTN |
| protein sialylation | biological process | ST6GALNAC2, ST3GAL4, ST3GAL2, ST8SIA3 |
| protein side chain deglutamylation | biological process | AGBL2, AGBL4, AGBL1 |
| protein stabilization | biological process | FKBPL, HSP90AA1, UBE2B, CDKN2A, GAPDH, CLU, BAG6, PTEN, PARK7, IGF1, HSPA1A, HSPA1B, HSPD1, SUMO1, WFS1, RASSF1, PEX19, RPL5, CCT5, CCT4, PER3, RPS7, STXBP4, STX12, GTPBP4, MCM8, PPIB, STK3, PTGES3, TBRG1, USP13, COA8, CCT7, PDCD10, AHSP, CAMLG, CDK7, RPL11, SWSAP1, TRIM39, A1CF, RTN4, PIK3R1, CCNH, CCT2, STK4, PIN1, FBXW7, TAF9B, SEC16A, PRKRA, CRYAB, TCP1, CCT6A, GOLGA7, MARCHF7, DVL1, EFNA1, MORC3, RABL3, SUGT1, ZNF207, PRKN, CTNND1, PFN2, HCFC1, TSC1, TRIM44, PPARGC1A, MDM4, BAG3, CCT3, NAA16, BAG5, GPIHBP1, C10orf90, LAMP2, MSX1, PHB2, HPS4, IFT46, WDR81, CDC37L1, USP33, NCLN, SMO, PINK1, TSPAN1, USP2, CCT8, DSG1, SAXO1, MTMR9, USP27X, FLOT1, WIZ, APOA1, TAF1, RASSF2, ANK2, EP300, AAK1, SAV1, TYROBP, CREBL2, ATF7IP, USP36, NLK, SEL1L, GNAQ, USP7, NAA15, PML, PRKCD, CHP1, HYPK, IRGM, EPHA4, SOX4, USP9X, TESC, GTSE1, TBL1X, LAMP1, CDKN1A, DSC3, SYVN1, ATP1B1, H1-5, MT3, GRN, COG7, ZBED3, RPL23, TNIP2, DVL3, COG3, WNT10B, PLPP3, ATP1B2, P3H1, MUL1, CRYAA, VHL, PIM2, ATP1B3, TREX1, HIP1R, CALR, SMAD3, PYHIN1 |
| protein sulfation | biological process | NDST1, CHST4, HS3ST3B1, CHST5, UST |
| protein sulfhydration | biological process | CTH |
| protein sumoylation | biological process | TP53, BRCA1, BIRC5, MDM2, CDKN2A, PARP1, PCNA, SUMO1, XPC, TOP2A, RANGAP1, TOP1, HDAC4, NUP93, BCL11A, SENP2, PIAS1, SUMO3, NUP37, NSMCE2, NUP88, NUP85, IFIH1, NUP107, NUP43, POM121, SENP6, NUP35, NUP58, PIAS2, SUMO2, NUP205, SENP5, NUP50, NUP62, ZMIZ1, NUP155, NUP153, UBA2, UBE2I, RAE1, SEH1L, ZBED1, NUP133, ZNF451, SENP1, EGR2, KIAA1586, NUP54, TPR, RANBP2, NUP98, EYA1, MUL1, TRPM4, AAAS, PIAS3, PIAS4, NUP210, CBX4, ZMIZ2, NUP188, TOPORS, SAE1, NUP42, NUP214, NUP160 |
| protein targeting | biological process | YWHAQ, KATNB1, LTBP2, PAN3, STXBP4, ERBIN, TRAK2, AKAP12, RPL11, SYNGR1, RAB27A, SRPRA, GIPC1, RHOD, CACNG3, LAMP2, SEC61G, YWHAZ, HPS4, TRAK1, YWHAE, TOMM20, AP1S3, AP4S1, GABARAP, PML, NUP54, YWHAB, SORL1, OS9, AP4M1, YWHAG, AP4B1, MYO1C, TOMM20L, KIF13B, AKAP5, HOMER3, RASSF9, HAP1, SYNJ2BP, CDC37, AP4E1, AKAP6 |
| protein targeting to ER | biological process | SPCS3, SPCS1, SRPRA, SPCS2, SRP14, SEC61G, ZFAND2B, PMM1, SRP54, SEC61A1 |
| protein targeting to lysosome | biological process | SNX16, AP3M1, NCOA4, AP3B1, SCARB2, HGS, M6PR, ZFYVE16, NEDD4, RAB7A, SORT1, GCC2, SORL1, AP4M1, NAGPA |
| protein targeting to lysosome involved in chaperone-mediated autophagy | biological process | HSPA8, LAMP2 |
| protein targeting to membrane | biological process | RTP5, RAB3IP, NACA2, SEC63, GOLGA7, CACNG2, AQP11, ZDHHC14, ZDHHC6, ZDHHC23, TAOK2, ARL6, RABGEF1, PARD3, ZDHHC19, NCF1, YIF1B, ZDHHC21, VPS37C, SDCBP, ZDHHC11, ATG3, ZDHHC20, EXOC4, ZDHHC3, ZDHHC2, VPS37A, VPS37B, RTP3, ZDHHC7, ZDHHC24, ZDHHC4, MYO1C, RTP1, NACAD, MICALL1, ZDHHC22, ZDHHC12, ZDHHC18, ZDHHC1 |
| protein targeting to mitochondrion | biological process | MFF, TIMM9, AIP, TOMM22, SLC25A6, TOMM34, TOMM70, DNAJC19, BID, TIMM13, TOMM5, TOMM7, TOMM20, TIMM17B, MFN2, FIS1, TIMM17A, TIMM10B, TIMM8B, TIMM44, TIMM10, FBXO7, MTERF4, TOMM40, PITRM1, GDAP1 |
| protein targeting to peroxisome | biological process | PEX7, MLYCD, PEX2, PEX19, UBE2D3, SCP2, ECH1, HACL1, AMACR, AGPS, RPS27A, LONP2, GNPAT, PHYH, ACAA1, IDE, BAAT, PEX26, PEX5, PEX13, ECI2, ACOX3, PEX12, CRAT, ZFAND6, PAOX, PEX14, UBC, PEX1, UBE2D1, UBA52, USP9X, HAO2, SLC27A2, AGXT, PEX16, HMGCL, ACOT2, DDO, PIPOX, UBB, DECR2, ACOX2, MPV17, ACOX1, ACOT4, HAO1, PECR |
| protein targeting to plasma membrane | biological process | GAS6, ANXA2, ANK1 |
| protein targeting to vacuole | biological process | VPS41, VTI1B, AP3D1, VPS13C, VPS13D, VPS37C, MON1B, GOSR2, PIK3R4, VPS37A, VPS37B, MON1A, VTI1A |
| protein tetramerization | biological process | TP53, HLA-DRB1, CAT, IGF1R, CCL5, TP63, NUDT21, CUTC, SNCA, PEX5, PKD2, PKD2L1, TRPM3, SHMT2, CPSF7, MS4A1, HOMER1, OXA1L, KCNC1, CPSF6, TRPM1, KCNC3, TRPM6 |
| protein to membrane docking | biological process | SNX3, RAB7A, STXBP3, PEX16 |
| protein transmembrane transport | biological process | MCL1, AZGP1, TOMM22, TOMM70 |
| protein transport | biological process | RAP1A, GOPC, PEX7, KPNA4, SNX3, USO1, ARF4, ARCN1, NASP, VPS41, RAB9A, NACA, TRAM1, RAB11FIP2, STX12, NUP93, TIMM21, AP5M1, SENP2, RAB18, KIF17, RAB21, DENND2A, TMED5, CHMP2A, ASTN2, VPS26A, KIF20A, BTF3, CETN2, KPNA2, SNX16, RAB11A, MTM1, MLC1, RABEP1, SEC23B, HIKESHI, DOP1A, EHBP1, NUP37, SCFD2, RAB2B, SFT2D1, SNX19, NUP88, TSG101, SEC22C, NUP85, BBS2, ENY2, SAR1A, ARL8B, VPS29, ANKRD50, AP3M1, ARFGEF1, SERP1, RAB29, ZW10, SEC22B, KDELR2, PPT1, AP2S1, RAB38, NUP107, CCDC93, CCDC91, VPS52, SLC15A4, NUP43, POM121, RAB3IP, LYST, RAB11FIP5, XPO4, NACA2, TXNIP, USE1, CHMP5, VPS18, SEC63, IPO11, VPS28, SNX7, SNX6, EXOC6B, GOLT1B, TTC26, SNAP23, KPNA5, AP5Z1, SNX2, SEC31A, GOSR1, PIK3R1, COPB2, GDI2, COPB1, COPZ1, RAB1A, WASHC5, ACAP1, AP1AR, ABRA, BBS5, NUP35, DTX3L, SNX27, SEC62, DERL1, NUP58, CEP41, LMAN2L, BLZF1, AKTIP, ZMAT3, VTA1, RAB6B, TIMM9, AP3B1, XPO1, SEC16A, KDELR3, STX10, VPS4B, HSP90B1, XBP1, NSF, SEC24C, SEC13, RAB2A, CALCRL, GRIPAP1, WASHC2A, C2CD5, SCFD1, NUP205, ENTR1, ANKRD27, IPO9, CHMP4A, ATG |
| protein transport along microtubule | biological process | BAG3, KIF1A, CAMSAP3 |
| protein transport from ciliary membrane to plasma membrane | biological process | ARL6, RILPL2, RILPL1 |
| protein transport into membrane raft | biological process | RFTN1 |
| protein transport into plasma membrane raft | biological process | CLIP1, ATP1B1 |
| protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | biological process | VPS28, VPS36, STAM, SNF8, VPS25 |
| protein transport within lipid bilayer | biological process | ITGB1 |
| protein trimerization | biological process | CD74 |
| protein ubiquitination | biological process | BRCA1, BIRC5, AKT1, UBE2B, MDM2, NFE2L2, UBR2, CDC42, CDC20, RNF114, RNF8, KLHL10, MALT1, PJA2, MED7, PEX2, TTC3, UBE2D3, UBE3A, ELOC, FBXO43, DCAF17, RNF20, FBXO38, MARCHF3, TRIM69, SIAH1, UBR7, DCAF11, RNF34, UBE2W, FEM1C, SELENOS, WAC, HECW2, MKRN1, TRIM17, NUB1, TRIM24, UBR5, UBE4A, KEAP1, TRIP12, UBE3C, TRIM74, FBXO11, MIB1, ZNRF2, RAB40A, ASB12, MED8, ITCH, CRBN, DDA1, RNF26, TRIM4, CISH, WSB2, KLHL8, SOCS2, TRIM13, CNOT4, SKP1, XIAP, CDC16, DCAF12, BRAP, CUL9, RNF168, RNF149, COP1, ASB17, RNF183, ZFP91, WDR61, KLHL25, TRIM39, RNF19A, CDC23, FBXL5, PRPF19, HIF3A, SIAH2, LTN1, BCL10, NFX1, TRIM25, FBXL22, UBE2R2, UBE3B, HUWE1, DTX3L, TRPC4AP, UBE2Q2, FBXW7, PELI1, DERL1, TULP4, DCAF13, FBXL12, RNF14, FZR1, BTRC, ARIH1, SOCS5, TRIM37, UBE2N, UBE2G1, RPS27A, RACK1, TNFAIP1, HERC4, MEX3C, KCTD9, RNF144B, TRIM58, SOCS4, ANAPC16, TRIM11, MKRN2, IRF2BPL, ASB8, MARCHF7, FBXO9, TRIM3, NEURL1, ARIH2, KLHL22, RBBP6, UBE2Q1, DZIP3, CBLL2, PAF1, ARRDC4, KCTD13, DDB2, CHFR, NEURL4, TRIM9, TRIM2, RNF41, DTL, ANAPC5, F |
| protein ubiquitination involved in ubiquitin-dependent protein catabolic process | biological process | CDK1, CCNB1, MDM2, CDC20 |
| protein ufmylation | biological process | CDK5RAP3, UBA5, UFM1, UFC1 |
| protein unfolding | biological process | HSP90AA1, ANGPTL4 |
| protein urmylation | biological process | MOCS3, URM1, CTU1, CTU2 |
| protein-chromophore linkage | biological process | OPN5, CRY1, AMBP, CRY2, RHO, OPN4, OPN3 |
| protein-containing complex assembly | biological process | FANCA, CLDN14, WDR19, TUBGCP4, LPXN, LAMC1, GLDC, MAX, MPP6, TCAP, ZW10, CD74, WASF3, NDUFAF1, EPRS1, ST13, AIMP2, RIMS1, DLG5, KIFAP3, SLC9A3R1, WIPF1, CAPZA1, HES1, KPNA3, CREBBP, PPARGC1A, LIN7A, MDM4, NUPR1, CAPN3, SSBP3, SAMM50, PICALM, IL1RAP, TSPAN4, MITF, PPID, CARD10, BID, SLC7A9, GEMIN5, PARD3, SNX9, CD3E, LLGL1, IKBKG, CD3G, APC, KMT2A, ELOB, VAMP3, DET1, MDN1, AFG3L2, TAPBP, TEAD2, ATPAF1, SKAP2, TEAD1, ADD2, CAPZA2, MAGI1, GPAA1, PEX14, PML, NIFK, GCH1, YAP1, WASF1, PARD6B, CD2AP, CAPG, DLG4, FANCC, APBA1, PPIH, REPS2, IL2RB, NCKAP1L, FGA, WAS, MNAT1, DMTN, OXA1L, SLC9A3R2, TUBGCP2, TRAF1, CHCHD10, ZNF148, PPP2R1A, NUP210, SHANK1, CD40, TRAF2, EPB41, TFAP4, PTK2B, VIL1, KNTC1, NAPG, TP53, ADGRL4 |
| protein-containing complex assembly involved in synapse maturation | biological process | NRXN1 |
| protein-containing complex disassembly | biological process | NAPA, HDAC6 |
| protein-containing complex subunit organization | biological process | WASHC5 |
| protein-DNA complex assembly | biological process | HNF1B, PIAS1, SOX12, TCF4, HEY2 |
| protein-DNA complex disassembly | biological process | RPL23 |
| protein-DNA covalent cross-linking | biological process | HMCES |
| protein-FAD linkage | biological process | SDHAF2 |
| protein-pyridoxal-5-phosphate linkage | biological process | GAD1 |
| protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine | biological process | CTH |
| proteoglycan biosynthetic process | biological process | IGF1, BMPR2, CSGALNACT1, CHST12, FAM20B, GAL3ST3, XYLT2, ACAN, XYLT1, CHST9, CANT1, CHST13, CHST10, CHST8, CHST11, GAL3ST4, CSGALNACT2 |
| proteoglycan catabolic process | biological process | ADAMTS12 |
| proteoglycan metabolic process | biological process | COL11A1, HPSE, PPARD, COL2A1, CNMD, BMP2, IHH |
| proteolysis | biological process | USP9Y, F10, MMP2, ACE, MMP9, CASP1, CASP4, CASP6, USP1, CASP3, CASP9, CASP8, USP26, C3, KLK3, CTSD, CLCA4, ASRGL1, PARK7, ADAMTS1, ADAMTS5, LTF, ACR, HGF, CD46, PDIA3, MMP12, DPP6, PLAU, PLAT, MMP7, ADAMTS20, SHH, DPP8, ELANE, PIP, PSMA3, LCN1, USP8, CPN1, ACE2, MALT1, EIF3H, PMPCB, LTA4H, PSMB1, PSMB5, SEC11A, LACTB, UBE3A, AGBL2, AGBL4, USP38, PSMA8, ADAM32, COPS5, USP47, PARL, SENP2, ERAP1, PSMA7, CPM, PSMA1, PSMA2, PSMA5, PSMB2, METAP2, ERAP2, SPPL2A, USP13, PSMB7, SEC11C, CPVL, UFSP2, EIF3F, CLPX, CTSK, USP14, CTSW, OLR1, BLMH, PSMD6, MINDY4, ERMP1, AOPEP, TRAPPC12, HMCES, SENP6, KLK9, USP16, ATP23, USP3, PSMD14, CFD, CAPN2, UQCRC2, CPS1, SPCS3, ESPL1, CPZ, CPXM2, MINDY1, MINDY3, FOLH1B, CPQ, SPCS1, CTSV, ZMPSTE24, PROC, CTSL, CTSB, ECE2, EEF1AKMT4-ECE2, PGC, TPSB2, PSMB6, ECE1, UBE2N, SPCS2, TPSAB1, CLPP, USP32, OMA1, STAMBPL1, SENP5, GGTLC1, DPEP3, DPP3, ADAM29, ADAM11, LAP3, PSMD8, CTSC, NPEPPS, GGTLC2, AMZ2, LONP2, ATG4A, CAPNS2, IMMP1L, USP28, DESI2, RNPEP, USP29, NRIP3, RHBDL2, FBXO2, FBXO3, HTRA2, |
| proteolysis involved in cellular protein catabolic process | biological process | CASP8, HSPA5, PSMA3, PSMB1, PSMB5, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, CPVL, CLPX, CTSK, CTSW, CAPN2, CTSV, CTSL, CTSB, PSMB6, CLPP, CTSC, PSMB4, LGMN, IDE, PSMB8, PSMA6, CTSA, RSPRY1, SCPEP1, CTSF, PSMB9, NRDC, PSMA4, DNAJC3, RNF123, GZMA, CTSS, PSMB3, PLG, CTSZ, ADAMTS7, CTSH, LONP1, ADAMTS12, PSMB10 |
| proton transport | biological process | ATP6V0A2, MT-ATP6, MT-ATP8, MT-CYB, NOX5 |
| proton-transporting V-type ATPase complex assembly | biological process | PIP4P1 |
| protoporphyrinogen IX biosynthetic process | biological process | PPOX, UROD, IREB2, HMBS, ALAD, UROS, ALAS1 |
| protoporphyrinogen IX metabolic process | biological process | PPOX, FECH, EIF2AK1 |
| proximal tubule development | biological process | AQP11, DLL1 |
| proximal/distal axis specification | biological process | SIX3 |
| proximal/distal pattern formation | biological process | CTNNB1, CYP26B1, ALDH1A2, TP63, GLI3, PBX2, CHSY1, HOXB9, SP8, HOXC9, PBX1, HOXC10, HOXD10, GLI1, EN1, HOXC11, DLL1, HOXA11, HOXA9, DLX1, LRP4, GLI2, DLX2, GREM1, HOXA10 |
| proximal/distal pattern formation involved in metanephric nephron development | biological process | IRX1 |
| proximal/distal pattern formation involved in nephron development | biological process | IRX3 |
| pseudopodium organization | biological process | RAB25 |
| pseudouridine synthesis | biological process | DKC1, RPUSD4, NOP10, RPUSD3, TRUB1, PUSL1, PUS10, PUS3, NAF1, PUS7L, RPUSD1, TRUB2, PUS7, GAR1 |
| psychomotor behavior | biological process | C12orf57, GRP, DPP4 |
| pteridine-containing compound biosynthetic process | biological process | GCH1 |
| pteridine-containing compound metabolic process | biological process | MTR |
| pulmonary artery endothelial tube morphogenesis | biological process | BMP4 |
| pulmonary artery morphogenesis | biological process | LRP2, SEC24B, HEY2, JAG1, STRA6 |
| pulmonary myocardium development | biological process | SEMA3C, NKX2-5 |
| pulmonary valve development | biological process | RBPJ |
| pulmonary valve formation | biological process | TBX20, GJA5 |
| pulmonary valve morphogenesis | biological process | NFATC1, NOTCH1, ROBO2, SMAD6, TGFB2, HEY2, HEY1, JAG1, STRA6, SLIT2, ROBO1 |
| pulmonary vein morphogenesis | biological process | TBX20 |
| purine deoxyribonucleoside metabolic process | biological process | DGUOK |
| purine deoxyribonucleoside triphosphate catabolic process | biological process | NUDT15 |
| purine nucleobase biosynthetic process | biological process | SHMT1, GMPS, GART, PAICS, MTHFD1L, PPAT, PFAS |
| purine nucleobase catabolic process | biological process | DPYD |
| purine nucleobase metabolic process | biological process | IL1B, ACPP, GMPR2, PRPS1, GMPR, URAD |
| purine nucleobase transmembrane transport | biological process | SLC28A2, SLC28A1, AQP9, SLC28A3 |
| purine nucleobase transport | biological process | AQP9 |
| purine nucleoside metabolic process | biological process | OARD1, MACROD2, PNP, MACROD1 |
| purine nucleoside monophosphate catabolic process | biological process | NT5C1A |
| purine nucleoside transmembrane transport | biological process | SLC28A2, SLC29A2, SLC29A1, SLC28A3 |
| purine nucleotide biosynthetic process | biological process | MTHFD1, PRPS1L1, GMPS, GART, OAS1, ATIC, PAICS, ADSS2, PRPS1, ADSS1, ADSL, HPRT1, PRPSAP1, MTHFD2L, PPAT, IMPDH2, IMPDH1, PFAS, PRPSAP2 |
| purine nucleotide catabolic process | biological process | GPX1, CAT, XDH, NUDT15, PNP, NT5C1A, ITPA, NT5C, DNPH1, NT5E, NUDT1, NT5C1B, GDA, NT5C2 |
| purine nucleotide metabolic process | biological process | AK2, GMPR2, GUK1, AK4, FHIT, AK1, AK9, ADSS1, ADSL, CMPK1, AK3, NME2, AK8, NME3, GMPR, AK7, NME1, NME4 |
| purine nucleotide salvage | biological process | ADA |
| purine nucleotide transport | biological process | ABCC11 |
| purine ribonucleoside diphosphate catabolic process | biological process | ENTPD2 |
| purine ribonucleoside monophosphate biosynthetic process | biological process | GMPS, GART, ATIC, PAICS, ADSS2, AMPD2, LHPP, ADSS1, ADSL, ADA, AMPD3, PPAT, IMPDH2, IMPDH1, PFAS |
| purine ribonucleoside salvage | biological process | ADK, APRT, HPRT1, MTAP, PRTFDC1 |
| purine ribonucleotide biosynthetic process | biological process | ADSL |
| purine ribonucleotide catabolic process | biological process | HINT1 |
| purine ribonucleotide interconversion | biological process | GMPR2, GMPR |
| purine ribonucleotide transport | biological process | GJB1 |
| purine-containing compound salvage | biological process | ADK, GMPR2, PNP, AMPD2, DCK, APRT, DGUOK, ADAL, HPRT1, ADA, AMPD3, GMPR |
| purinergic nucleotide receptor signaling pathway | biological process | ANO6, P2RX7, P2RX6, P2RX4, P2RX5, P2RX3, P2RX2 |
| Purkinje myocyte development | biological process | DSG2 |
| Purkinje myocyte differentiation | biological process | NKX2-5 |
| Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling | biological process | GJA5 |
| Purkinje myocyte to ventricular cardiac muscle cell signaling | biological process | CASQ2, RYR2 |
| putamen development | biological process | FOXP2 |
| putrescine acetylation | biological process | SAT2 |
| putrescine biosynthetic process | biological process | AGMAT, ODC1, PAOX |
| putrescine biosynthetic process from arginine | biological process | AGMAT |
| putrescine biosynthetic process from arginine, using agmatinase | biological process | AGMAT |
| putrescine biosynthetic process from ornithine | biological process | ODC1, AZIN1, AZIN2 |
| putrescine catabolic process | biological process | SAT1, SAT2, PAOX |
| putrescine transport | biological process | OAZ3 |
| pyramidal neuron development | biological process | FGFR2, UQCRQ, ATP7A, PLXNA3, SLC4A10 |
| pyramidal neuron differentiation | biological process | UNC5D |
| pyramidal neuron migration | biological process | ZMIZ1, DISC1, FOXG1 |
| pyridine nucleotide biosynthetic process | biological process | HAAO, NMNAT1, NMRK1, KYNU, NMNAT3, NAMPT, NAPRT, ASPDH, QPRT, NMNAT2, NMRK2 |
| pyridoxal 5'-phosphate salvage | biological process | PDXK |
| pyridoxal phosphate biosynthetic process | biological process | PDXK, PNPO |
| pyridoxal phosphate catabolic process | biological process | PDXP |
| pyridoxine biosynthetic process | biological process | PSAT1, PNPO |
| pyrimidine deoxyribonucleotide catabolic process | biological process | NT5C, NT5M |
| pyrimidine dimer repair | biological process | POLH, ERCC6, DDB2, MSH6, POLB |
| pyrimidine dimer repair by nucleotide-excision repair | biological process | ERCC1, HMGN1 |
| pyrimidine nucleobase biosynthetic process | biological process | CTPS1, UMPS, CTPS2 |
| pyrimidine nucleobase metabolic process | biological process | TYMS, RRM1, TYMP |
| pyrimidine nucleobase transport | biological process | SLC28A2, SLC28A1, AQP9, SLC28A3 |
| pyrimidine nucleoside biosynthetic process | biological process | DHODH, UMPS, CAD |
| pyrimidine nucleoside catabolic process | biological process | DPYS, NT5C1A, NT5C, NT5E, UPP1, UPB1, TYMP, DPYD, NT5M, UPP2 |
| pyrimidine nucleoside metabolic process | biological process | TYMP, ERH |
| pyrimidine nucleoside salvage | biological process | UCK1, UPP1, UCKL1, DCK, CDA, PUDP, UCK2, TYMP, TK2, UPP2, TK1 |
| pyrimidine nucleoside transport | biological process | SLC28A3 |
| pyrimidine nucleotide biosynthetic process | biological process | CTPS1, PRPS1, CMPK1, DHODH, UMPS, CAD, CTPS2 |
| pyrimidine nucleotide import into mitochondrion | biological process | SLC25A33, SLC25A36 |
| pyrimidine nucleotide metabolic process | biological process | ENPP3, UPP1, DCK, NME2, NME3, NME1, DCTD, NME4, CTPS2 |
| pyrimidine nucleotide transport | biological process | SLC25A33, SLC25A36 |
| pyrimidine nucleotide-sugar transmembrane transport | biological process | SLC35A1, SLC35D1, SLC35D2, SLC35A5, SLC35A3, SLC35A4, SLC35E4, SLC35A2 |
| pyrimidine ribonucleotide biosynthetic process | biological process | CMPK1, DHODH |
| pyrimidine-containing compound salvage | biological process | CDA |
| pyrimidine-containing compound transmembrane transport | biological process | SLC28A2, SLC28A1, AQP9, SLC29A2, SLC29A1, SLC28A3 |
| pyroptosis | biological process | CASP1, GSDME, NLRP9, NAIP, GSDMB, APIP, ZBP1, AIM2, GSDMD, GSDMA, GSDMC |
| pyroptosome complex assembly | biological process | AIM2 |
| pyruvate biosynthetic process | biological process | PKM, AGXT, SDS, HOGA1, SRR, PKLR |
| pyruvate metabolic process | biological process | LDHC, LDHA, LDHB, GLO1, PDHA1, ME1, PCK2, PDHX, PC, PFKFB2, PDHB, LDHAL6B, HAGH, SLC16A8, ME2, SLC16A1, ME3, DLAT |
| pyruvate oxidation | biological process | NR4A3 |
| pyruvate transmembrane transport | biological process | SLC16A7, SLC16A11 |
| quaternary ammonium group transport | biological process | SLC22A5, SLC22A4, SLC22A1, SLC22A3 |
| quinolinate biosynthetic process | biological process | HAAO, KYNU |
| quinolinate catabolic process | biological process | QPRT |
| quinolinate metabolic process | biological process | HAAO, QPRT |
| quinone metabolic process | biological process | ADH4, CRYZL1 |
| quorum sensing involved in interaction with host | biological process | SLC22A5 |
| R-loop disassembly | biological process | DDX23, DDX21, SRPK2, SIRT7, PRIMPOL |
| Rab protein signal transduction | biological process | RAB9A, IFT22, RAB18, RAB21, RAB11A, RAB2B, RAB40A, RAB29, RAB38, RAB27A, RAB1A, RAB6B, DNAJC27, RAB2A, RAB4A, RABL3, RAB3C, RAB6A, RAB25, RAB5A, RAB31, RAB32, RAB8B, RAB20, RAB40B, RAB35, RAB22A, RAB27B, RAB15, RAB30, RAB3B, RAB14, RAB23, RAB7A, RAB39A, RAB11B, RAB28, RAB40C, RAB26, RAB6D, RAB4B, RAB33B, RAB5B, RAB5C, RAB8A, RAB33A, RAB34, RAB17, RAB3D, RAB37, RAB1B, RAB36, RAB40AL, GDI1, RAB9B, RABL2B |
| Rac protein signal transduction | biological process | AIF1, ALS2, NCKAP1, GARRE1, RHOU, ABI2, RHOG, DBNL, HACD3, EPS8, TIAM1, RAC1, WASF2, RAC2, CYFIP1, HACE1, WASF1, FARP2, CDH13, NISCH, ELMO1 |
| radial glia guided migration of Purkinje cell | biological process | RBFOX2, RERE, CTNNA2 |
| radial glial cell differentiation | biological process | STAT3, EMX1, GPR157, FGF10 |
| radial pattern formation | biological process | NR2F2 |
| Ran protein signal transduction | biological process | GPSM2, RCC1 |
| random inactivation of X chromosome | biological process | RLIM |
| Rap protein signal transduction | biological process | RAP1A, PLK2, RAP2B, RAPGEF2, RAPGEF1, RAPGEF3, RAP2A, SGSM3, RAP1B |
| Ras protein signal transduction | biological process | TP53, DNMT1, CDKN2A, PARK7, IGF1, RB1, SOS1, RASSF1, CCNA2, MAPK14, SHTN1, G3BP1, RIT1, PLK2, BRAP, SHC1, MAPK11, RASGRP3, RALA, PLD1, KRAS, PRKD1, IQGAP3, USP28, SHOC2, RRAS, GNB1, DHCR24, MAPKAPK5, RAPGEF6, CNKSR1, GRAP2, RASGRP1, NTN1, RASGRP2, RIT2, RRAS2, ADRA2A, PLCE1, RALB, GRB2, KSR1, SETDB1, G3BP2, RREB1, RGL2, CDKN1A, DOK3, GRAP, DOK2, HRAS, RFXANK, LAT, FGF2, DOK1, RALGDS, SHC2, MRAS, NF1, KSR2, SHC3, CRKL |
| rDNA condensation | biological process | NIPBL |
| re-entry into mitotic cell cycle | biological process | GSK3B, CCND1, CCNF |
| reactive nitrogen species metabolic process | biological process | PRDX5 |
| reactive oxygen species biosynthetic process | biological process | INAVA, GBF1 |
| reactive oxygen species metabolic process | biological process | SOD1, BCL2, PRDX4, EPHX2, CCN1, CCN2, PDK4, NDUFAF2, NDUFS4, PDGFB, IFI6, NNT, CYBA, NDUFS1, ATP5IF1, PLA2R1, BNIP3, RFK, P2RX7, SFTPD, MPV17L, PREX1, GLS2, SESN2, VAV1, DUOX1, SH3PXD2A, LRRK2 |
| receptor biosynthetic process | biological process | TNF, IL10, ACE2 |
| receptor catabolic process | biological process | TGFB1, SH3GLB1, LGMN, KIF16B, NEDD4, BECN1, PIK3R4, UVRAG, CAPN1, MVB12A, CDK5, SNX25 |
| receptor clustering | biological process | ITGA4, PICK1, PTN, DVL1, LRRC1, MADCAM1, SCRIB, PIGR, ITGB1BP1, DLG1, GRIK5, ITGB7, DLG4, ITGB2, TMEFF1, DLG3, CDK5, THY1, TMEFF2, AGRN, LRP4, ITGAL, GRIK2, DLG2, SYNJ2BP, MAGI2 |
| receptor guanylyl cyclase signaling pathway | biological process | GUCY2F, PDZD3, NPR1, GUCY2D, NPPC, NPR2 |
| receptor internalization | biological process | CXCL8, ADM, ITGB1, EZR, CD9, SNCA, CD81, CALCRL, TFRC, GRK4, SYK, RAMP2, RAB31, PICALM, DNM3, CNTN2, MX1, GRK2, ACKR3, NEDD4, AP2M1, CXCR2, GHR, GRB2, GRK3, CLTC, RAMP3, ITGB2, CALCA, LRP1, MX2, CXCR1, FCER1G, RAMP1, DNM1, ARRB2, GRIA1, CD36, CAV1 |
| receptor internalization involved in canonical Wnt signaling pathway | biological process | RAB5A, SCYL2, CAV1 |
| receptor localization to non-motile cilium | biological process | ARL13B, IFT80, BBIP1, TUB |
| receptor localization to synapse | biological process | CEP112, NRXN1, LRRC1, SCRIB, DLG1, DLG4, DLG3, DLG2, SYNJ2BP, RELN, NETO1 |
| receptor metabolic process | biological process | FUT8 |
| receptor recycling | biological process | LMTK2, PHETA2, CAMLG, ALS2, PHETA1, ARFGEF2, RAB11B, PLEKHJ1, EHD3, NSG1 |
| receptor signaling pathway via STAT | biological process | THPO |
| receptor transactivation | biological process | NCOA3, ADRA2A, ADRA2B, ADRA2C |
| receptor-mediated endocytosis | biological process | APOE, APOB, HSP90AA1, ALB, IGF2R, LGALS3BP, SAA1, HSPH1, PPT1, RABEPK, MAPK8IP1, PIKFYVE, HSP90B1, REPS1, AP1G1, SCARB2, CXCL16, TFRC, AP1S1, DAB2, LDLR, M6PR, CTTN, COLEC12, SCARB1, AP2A2, FCGR2B, VLDLR, PICALM, ADRB2, ITGAM, ADRB3, MRC1, COLEC11, MARCO, DMBT1, AP1G2, DBNL, MASP1, HBB, ARHGAP27, SNX9, PLA2R1, STAB1, APOA1, LRP2, TMEM108, AMN, CLTCL1, CLTC, HSPG2, WASF1, SORL1, GAK, DNAJC6, CLN3, LMBR1L, PDLIM7, TFR2, HYOU1, HPR, ITGB2, LRP1, LRP1B, HP, FPR2, SFTPD, TGFBR2, CLEC9A, PI4KB, HBA1, DNM1, CD163, LRP3, AP2A1, AMBP, MAPK8IP2, HIP1R, CALR, SCARF1, SNX17, MICALL1, CUBN, CAP1, STAB2, AP4E1, APOL1, ASGR1, FOLR1, CD36 |
| receptor-mediated endocytosis involved in cholesterol transport | biological process | LDLR, LRP6 |
| receptor-mediated endocytosis of virus by host cell | biological process | EPS15, CAV2, CAV1 |
| receptor-mediated virion attachment to host cell | biological process | ICAM1, GAS6, ACE2, CD81 |
| reciprocal meiotic recombination | biological process | ATM, SPO11, MSH4, REC8, MLH1, TEX11, MLH3, STRA8, MSH2, SYCP1, DMC1, RAD51C, TRIP13, PSMC3IP, CCNB1IP1, MRE11, TOP6BL, RAD21, SYCE3, CNTD1, RAD50, RAD51B, RAD51D, TEX19, KLHDC3, RAD54B, RAD54L |
| recognition of apoptotic cell | biological process | MEGF10, SCARB1, FCN3, FCN1, PEAR1 |
| recombinational interstrand cross-link repair | biological process | MCM8, MCM9 |
| recombinational repair | biological process | FBH1, HROB, RHNO1 |
| recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex | biological process | POLR2D, CDC73 |
| recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex | biological process | RAMAC |
| recycling endosome to Golgi transport | biological process | GCC2, TBC1D14 |
| reduced folate transmembrane transport | biological process | SLC19A1 |
| reduction of food intake in response to dietary excess | biological process | NMUR2, PRLH, RMI1 |
| reelin-mediated signaling pathway | biological process | DAB2IP, VLDLR, CRK, STAT5A, CRKL, RELN |
| reflex | biological process | SATB1 |
| regulated exocytosis | biological process | VPS41, RAB11FIP2, RAB11FIP5, SYNGR1, RIMS1, TMEM79, ABCA12, RAB31, CRHBP, RAB11B, STEAP2, RAB11FIP1, RAB26, TMED10, DNAJC5, SYNGR2, CDK5, MYH9, SYNGR3 |
| regulation of acetyl-CoA biosynthetic process from pyruvate | biological process | PDK4, PDK3, PDP1, PDK1, PDPR, GSTZ1, PDP2, PDK2 |
| regulation of acetylcholine secretion, neurotransmission | biological process | CHRNA3 |
| regulation of acid-sensing ion channel activity | biological process | STOM |
| regulation of acrosome reaction | biological process | CRISP1, SPINK1, B4GALT1, SERPINA10 |
| regulation of actin cytoskeleton organization | biological process | MTOR, EZR, PAM, BAIAP2, IQGAP1, IQGAP2, BST2, RHOU, IQGAP3, DLC1, ROCK2, ARHGAP35, ARHGEF5, GPM6B, CCDC88A, TAOK2, RHOG, EFNA5, ROCK1, ARHGAP17, ODAM, CELSR1, PDGFA, SMIM22, RHOQ, CDK5R1, VANGL2, RHOBTB3, RAC1, ARHGAP18, ABL1, RAC2, F11R, PRKCD, TAOK1, SIGLEC15, OR2A4, LRP1, ILK, CLASP2, PAK3, PDGFRB, RAC3, BST1, TWF2, MLST8, DMTN, RHOJ, CORO2B, HRG, EPHA3, CORO1A, CRK, RHOV, SH3BP1, HIP1R, FAM107A, FSCN1, ARHGAP44, GRHL3, DIXDC1 |
| regulation of actin cytoskeleton organization by cell-cell adhesion | biological process | JAM3 |
| regulation of actin cytoskeleton reorganization | biological process | TGFB1, ARHGDIA, SEMA3E, IQGAP2, PHPT1, RHOD, MDK, ABL1, F11R, ABL2, ARHGDIB, CD2AP, ESAM, RAPGEF3, PDGFRA, GMFG, CSF1R, TRPM2, PTK2B |
| regulation of actin filament bundle assembly | biological process | RDX |
| regulation of actin filament depolymerization | biological process | WDR1, SH3BP1 |
| regulation of actin filament length | biological process | NEB, EPS8 |
| regulation of actin filament organization | biological process | C9orf72, RGS4 |
| regulation of actin filament polymerization | biological process | RASA1, ARPC1A, COTL1, BAIAP2L1, ARPC3, ABITRAM, ARPC5, FCHSD2, HAX1, PFN2, CTTN, DBNL, CYFIP2, ARHGAP18, PLEKHG2, CYFIP1, GBA2, LATS1, HCLS1, ESAM, PPP1R9A, PAK3, PREX1, ELN, CORO1A, ARPC4, ARPC1B, PFN3, ARPC5L, CYRIA |
| regulation of actin filament-based process | biological process | FRMD6, CNN2, ABRACL, ROCK1 |
| regulation of actin nucleation | biological process | WASHC5, VIL1 |
| regulation of actin phosphorylation | biological process | TWF1 |
| regulation of actin polymerization or depolymerization | biological process | ARHGAP35, SWAP70, TMSB4Y, NAA80, WAS, CORO1A, CXCL12 |
| regulation of action potential | biological process | KCNB1, KCNAB2, NTSR1, CD36 |
| regulation of action potential firing pattern | biological process | SLC8A2 |
| regulation of activation of Janus kinase activity | biological process | SOCS1 |
| regulation of activation-induced cell death of T cells | biological process | RIPK3 |
| regulation of activin receptor signaling pathway | biological process | MEN1, FGF10 |
| regulation of acute inflammatory response | biological process | DNASE1L3, DNASE1 |
| regulation of acute inflammatory response to antigenic stimulus | biological process | PLA2G2D |
| regulation of adaptive immune response | biological process | FCGR2B, CD48, ADCY7, TNFSF4, IRF1, IRF7, RIPK3, CD160, DUSP10 |
| regulation of adaxial/abaxial pattern formation | biological process | EED |
| regulation of adenylate cyclase activity | biological process | NPFFR2, CAP2, CAP1 |
| regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway | biological process | CRHR1 |
| regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway | biological process | MRAP2 |
| regulation of adhesion of symbiont to host epithelial cell | biological process | SFTPD |
| regulation of adipose tissue development | biological process | PLAAT3 |
| regulation of aerobic respiration | biological process | HIF1A, IDE, CBFA2T3, SHMT2, BNIP3, ACTN3 |
| regulation of alternative mRNA splicing, via spliceosome | biological process | FMR1, RBMY1A1, HNRNPL, SRSF6, RBMX, RBFOX2, HNRNPU, IK, FAM172A, DYRK1A, NOVA2, HNRNPA1, FXR1, CELF5, SRSF12, YTHDC1, RBM15, SRSF8, RBM25, RBM10, WTAP, SAP18, RBM4B, TRA2B, SART3, REST, MBNL1, SRSF3, ZC3H10, MBNL3, RBM8A, CELF4, FXR2, SRSF7, PUF60, KHDRBS3, CELF2, SMU1, CELF6, MBNL2, RBM4, RBM17, QKI, RBFOX1, DDX17, RBM7, RBM15B, RBM24, RBM19, SRSF2, MYOD1, SF1, THRAP3, ZBTB7A, NSRP1, RBFOX3, SREK1, NOVA1, SRSF5, SRRM4 |
| regulation of AMPA glutamate receptor clustering | biological process | SHISA7, SHISA6 |
| regulation of AMPA receptor activity | biological process | CACNG2, GSG1L, NRXN1, NLGN2, CACNG3, CACNG7, CNIH3, MEF2C, SHANK2, CACNG4, CNIH2, MAPK8IP2, SHANK1, MINK1, SHISA7, SHISA6, CACNG8 |
| regulation of amyloid fibril formation | biological process | CHRNA7 |
| regulation of amyloid precursor protein biosynthetic process | biological process | NECAB1, NECAB3, NECAB2 |
| regulation of amyloid precursor protein catabolic process | biological process | CHRNA7, ABCA7, UNC13A |
| regulation of androgen receptor signaling pathway | biological process | PARK7, RNF14, TRIM68, RNF6, PRMT2, EP300, HDAC6, ARRB2, SAFB2 |
| regulation of angiogenesis | biological process | IL6, ERBB2, HMOX1, KRT1, CTNNB1, LEP, PROK2, PROK1, ENPP2, ADGRA2, EFNA1, WARS1, GPNMB, EMP2, VASH2, ETS1, SP100, HTATIP2, RNH1, TSPAN12, MAPK7, EGLN1, TNFRSF12A, EPHA2, FGF2, VASH1, PLXND1, NF1, PTK2B, RECK |
| regulation of angiotensin levels in blood | biological process | CPA3 |
| regulation of angiotensin metabolic process | biological process | ACE, SUCNR1 |
| regulation of angiotensin-activated signaling pathway | biological process | ROCK2, ROCK1 |
| regulation of animal organ formation | biological process | WT1, CITED2 |
| regulation of anion channel activity | biological process | TCAF2, TCAF1 |
| regulation of anion transmembrane transport | biological process | VDAC2, CLCN2, VDAC1 |
| regulation of anion transport | biological process | VDAC2, CA2, VDAC1, AHCYL1, RAB11B |
| regulation of anoikis | biological process | ANKRD13C |
| regulation of antigen processing and presentation | biological process | YTHDF1 |
| regulation of apoptosis involved in tissue homeostasis | biological process | PRDX5 |
| regulation of apoptotic cell clearance | biological process | ITGAV |
| regulation of apoptotic DNA fragmentation | biological process | CDKN2A, CIDEA, AIFM1 |
| regulation of apoptotic process | biological process | TGFB1, ESR1, TP53, IL6, BCL2, TGFB3, TNFRSF1A, TNFRSF1B, FAS, CASP1, BRCA1, SOX9, CASP4, CASP6, BAX, BAK1, BCL2L2, BIRC5, STAT1, CASP9, ATM, CASP8, BMP7, CTNNB1, BAG6, BAD, GDF15, GDF9, BMP15, IGF2R, RAF1, PRDX2, MCL1, INHA, TP63, 38231, TNFRSF25, MALT1, CIDEA, GLI3, IFT57, TRIM24, JAK2, TNFAIP8, FBXO11, CAAP1, BCL2L12, RTN4, PRELID1, TNFRSF10C, BCL10, ANP32A, BCL6, RBM25, RBM10, ANP32B, ALK, MAGED1, BCL2L11, CTSB, BCL3, TP53BP2, DLG5, DEDD2, TP53INP1, OMA1, RPS3, RABGGTB, NAE1, TP53I3, SERBP1, TNFAIP8L1, SDF2L1, HAX1, CREB3, PRKN, DEDD, EGR1, TRAF3, CREBBP, BNIP3L, PTPN6, GAS1, DIP2A, HS1BP3, ALPK2, RASSF3, ING2, TNFRSF10D, TNFRSF10B, BCAR1, CITED1, NOD2, FBXO10, HRK, PAX8, FADD, SARM1, RASSF5, CARD10, ACTN2, ETS1, CASP2, BID, PINK1, CFLAR, CD3E, BIRC2, SRA1, TRIAP1, LOX, PPIF, RASSF2, SKP2, RASSF6, LCMT1, ACTN1, ANP32E, BEX2, USP36, OSGIN1, SGK1, RIPK2, ABL1, OLFM4, SLK, STK26, TRAF6, CARD18, PEA15, FRS2, NLRP1, BOK, NME2, ABL2, CARD16, PERP, TRAF4, BCL2L14, DAPK1, NME3, ZNF420, CASP10, PPP1R13B, ALX4, CARD |
| regulation of apoptotic process involved in outflow tract morphogenesis | biological process | TGFB2 |
| regulation of appetite | biological process | HTR2C, SCT, SCTR, POMC, SLC22A3, GALP |
| regulation of arachidonic acid secretion | biological process | SYK |
| regulation of ARF protein signal transduction | biological process | ARFGEF1, CYTH3, FBXO8, PSD3, ARFGEF2, ARFGAP1, IQSEC1, PSD2, IQSEC3, PSD, CYTH2, PSD4, GBF1, CYTH4, CYTH1, ARFGEF3 |
| regulation of arginine biosynthetic process | biological process | CLN3 |
| regulation of arginine metabolic process | biological process | FH, SLC7A7 |
| regulation of Arp2/3 complex-mediated actin nucleation | biological process | PICK1, CORO1B, AP1AR, ARF1, ARFIP1 |
| regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process | biological process | PICALM |
| regulation of astrocyte chemotaxis | biological process | GPR183 |
| regulation of astrocyte differentiation | biological process | CNTN2, EPHA4 |
| regulation of asymmetric cell division | biological process | WNT9B |
| regulation of ATF6-mediated unfolded protein response | biological process | HSPA5 |
| regulation of ATP biosynthetic process | biological process | SPHK2, AK4 |
| regulation of ATP metabolic process | biological process | DNM1L, ATP5IF1 |
| regulation of ATPase activity | biological process | BRSK2, SNRNP70, VMA21, METTL21A, TMEM64, TPM2, MYH6, TNNT3 |
| regulation of ATPase-coupled calcium transmembrane transporter activity | biological process | SLN, PLN |
| regulation of atrial cardiac muscle cell action potential | biological process | RYR2, ANK2, GJA5 |
| regulation of atrial cardiac muscle cell membrane depolarization | biological process | GJA1, SCN1B, CACNA1G, GJA5, SCN5A, SCN10A, SCN2B, SCN3B |
| regulation of atrial cardiac muscle cell membrane repolarization | biological process | CACNA1D, SCN5A |
| regulation of attachment of spindle microtubules to kinetochore | biological process | CDC42, APC, ECT2, KNSTRN, NEK2 |
| regulation of auditory receptor cell differentiation | biological process | MYCN, NOTCH1, HEY2, MYCL |
| regulation of autophagosome assembly | biological process | IFT88, C9orf72, PIKFYVE, NPRL2, RAB5A, TBC1D12, MTMR3, NPRL3, RAB1B, TBC1D14 |
| regulation of autophagosome maturation | biological process | CLN3, CLEC16A, TBC1D25 |
| regulation of autophagosome size | biological process | ATP13A2 |
| regulation of autophagy | biological process | BCL2, CASP1, ATM, HSPB1, GPR137B, DDIT3, KEAP1, USP13, VPS29, TRIB3, C9orf72, ZMPSTE24, XBP1, TP53INP1, MTMR4, LAMP3, PRKN, RRAGA, NUPR1, CHMP4B, DEPDC5, PSAP, RRAGB, ULK2, MFSD8, MTMR8, ROCK1, WDR41, ULK1, USP33, PIP4K2A, EP300, DRAM1, ABL1, IFI16, DRAM2, PIP4K2C, BOK, ABL2, ITPR1, SMCR8, ERCC4, OSBPL7, RRAGD, DAPK1, MTMR3, TPCN2, RMC1, HDAC6, PIP4K2B, TMEM150A, PYCARD, USP10, DEPP1, DAPK2, RAB8A, FBXL2, MTCL1, PIK3R2, MAPK15, WDR24, SOGA1, RPTOR, ACER2, LRRK2 |
| regulation of AV node cell action potential | biological process | RYR2, CXADR, GJA5 |
| regulation of axon diameter | biological process | CNTN2, KEL, WNT7A, NEFL |
| regulation of axon extension | biological process | APOE, GSK3B, RAB21, DPYSL2, OLFM1, CTTN, WDR36, NRCAM, TTL, ABL1, BARHL2, CLASP2 |
| regulation of axon extension involved in axon guidance | biological process | SEMA3A, PLXNA4, NRP1 |
| regulation of axon guidance | biological process | YTHDF1, ZSWIM4, ZSWIM5, TBR1, ZSWIM8, MYCBP2, ZSWIM6 |
| regulation of axon regeneration | biological process | PTEN, KLF4, PTPRF, MAP2K1, LRIG2 |
| regulation of axonogenesis | biological process | GSK3B, LRRC4C, CHN1, GRIN1, MARK2, EFNA1, EPHB2, ARHGAP35, WNT3A, RUFY3, POU3F2, EPHA4, PAK3, RET, KIF13B, EPHB3, BRSK1, WNT7A, UST |
| regulation of B cell activation | biological process | CD19 |
| regulation of B cell antigen processing and presentation | biological process | FCGR2B |
| regulation of B cell apoptotic process | biological process | PTEN, LYN, BTK |
| regulation of B cell cytokine production | biological process | BTK |
| regulation of B cell differentiation | biological process | SLAMF8, PTPN6, CYLD, ZFP36L2, ZFP36L1, TLR9, NFAM1, CARD11 |
| regulation of B cell proliferation | biological process | AHR, CD22, MZB1 |
| regulation of B cell receptor signaling pathway | biological process | ELF2, ELF1, GCSAM, CBFB, RUNX1, GCSAML, PTPN22, PAX5, LYN, CD19, BLK |
| regulation of behavior | biological process | CCL3, AHI1, MDK, MBD5, HTR1B, RELN, HTR2B |
| regulation of beta-amyloid clearance | biological process | APOE, CLU |
| regulation of bicellular tight junction assembly | biological process | GJA1, TJP1, PRKCH, CLDN5, CBFB, RUNX1, F11R, FZD5, MYO1C, GPBAR1 |
| regulation of bile acid biosynthetic process | biological process | CES1, NR1H4, FGFR4 |
| regulation of bile acid metabolic process | biological process | PANK2, ABCB11 |
| regulation of bile acid secretion | biological process | CES1 |
| regulation of binding | biological process | TGFB1, SMAD4, SMAD2, SMAD3 |
| regulation of blood circulation | biological process | ZMPSTE24 |
| regulation of blood coagulation | biological process | F2R, EPHB2, HRG, SERPING1, GP1BA, F2, VKORC1, APOH, CAV1, FOXA2 |
| regulation of blood coagulation, intrinsic pathway | biological process | SERPINC1 |
| regulation of blood pressure | biological process | SOD1, ACE, PTGS1, NOS3, PTGS2, SOD2, HMOX1, CYP11B1, EDNRA, LEP, NRG1, EPHX2, PPARG, TAC1, ERAP1, ERAP2, NOX1, UTS2, GNB3, CD34, RAMP2, NPY, UTS2B, NPR3, GCGR, HBB, TAC4, EDNRB, GUCY1A1, COL1A2, BRS3, ATP1A2, SGK1, NPY1R, GCH1, ACSM3, UTS2R, LRP5, CALCA, NPR1, AGTRAP, NISCH, ATP1A1, EDN1, ATP2B1, DLL1, ACVRL1, RENBP, CYP4F2, P2RX4, POMC, MYH6, NPR2, CACNA1B, AGT, MC3R, ACTA2 |
| regulation of blood vessel diameter | biological process | UTS2, GCLC, ROCK2, ADRB2, UTS2B, AGTR1, ROCK1, ITGB1BP1, ADCY6, FOXC2, UTS2R, NPR1, GJA5, P2RY1, FOXC1, P2RY2 |
| regulation of blood vessel diameter by renin-angiotensin | biological process | SERPINF2, AGTR1, AGT |
| regulation of blood vessel endothelial cell migration | biological process | EFNA1, PRCP, EPHA2, ACVRL1, SH3BP1, NF1 |
| regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | biological process | FGF2 |
| regulation of blood vessel remodeling | biological process | TGFB1, FLT4, CEACAM1 |
| regulation of blood vessel size | biological process | NOS3 |
| regulation of blood volume by renal aldosterone | biological process | CYP11B2, HSD11B2 |
| regulation of blood volume by renin-angiotensin | biological process | DRD3, AGT |
| regulation of BMP signaling pathway | biological process | XIAP, FSTL1, FSTL3, PCSK6, TWSG1, FKBP8, SFRP5, SFRP4, ITGA3 |
| regulation of body fluid levels | biological process | EPHB2, PDSS2, APLNR |
| regulation of bone development | biological process | GLI3, LOX, KAT2A |
| regulation of bone mineralization | biological process | BGLAP, GJA1, ECM1, NBR1, SGMS2, ZMPSTE24, S1PR1, FGF23, BMP2K, OMD, ANKH, ENPP1, TXLNG, STATH, PHOSPHO1, CYP27B1, TWIST1, MGP, COMP, PTK2B, AHSG |
| regulation of bone remodeling | biological process | LEP, LEPR, GJA1, SUCO, MDK, CARTPT, SYT7 |
| regulation of bone resorption | biological process | BGLAP, SRC, PDK4, S1PR1, GPR137, ITGB3, SIGLEC15, CSF1R, NF1 |
| regulation of branch elongation involved in ureteric bud branching | biological process | HNF1B, SIX1, SIX4 |
| regulation of branching involved in lung morphogenesis | biological process | SOX9 |
| regulation of branching involved in mammary gland duct morphogenesis | biological process | TGFB1, ETV5, PHB2, CAV3 |
| regulation of branching involved in prostate gland morphogenesis | biological process | ESR1, FGFR2, BMP7, BMP4, HOXD13 |
| regulation of branching involved in salivary gland morphogenesis | biological process | TNF, BTBD7 |
| regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling | biological process | PDGFA |
| regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling | biological process | NTN4 |
| regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling | biological process | FGFR1, HGF, FGF7, FGF10 |
| regulation of branching involved in ureteric bud morphogenesis | biological process | SIX2 |
| regulation of branching morphogenesis of a nerve | biological process | RTN4, LRRK2 |
| regulation of brood size | biological process | SH3PXD2B |
| regulation of brown fat cell differentiation | biological process | LEP, MTOR, DUSP10 |
| regulation of bundle of His cell action potential | biological process | RANGRF, GJA5 |
| regulation of calcidiol 1-monooxygenase activity | biological process | VDR |
| regulation of calcineurin-mediated signaling | biological process | SLC8A2 |
| regulation of calcineurin-NFAT signaling cascade | biological process | RCAN2, EFHB, RCAN3, NFAT5, RCAN1 |
| regulation of calcium import into the mitochondrion | biological process | PSEN2 |
| regulation of calcium ion export across plasma membrane | biological process | RGS9 |
| regulation of calcium ion import | biological process | EGF, CTNNB1, WNK3, PKD2, CAV3, PLN, HOMER1, DYSF, PLPP4 |
| regulation of calcium ion import across plasma membrane | biological process | PRNP |
| regulation of calcium ion transmembrane transport | biological process | SUMO1, TSPAN13, PIK3CG, ATP1B1, HRC, TMC1, TMC2 |
| regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | biological process | CAMK2D, NOS1AP, CACNG6, CACNB1, CACNG1 |
| regulation of calcium ion transmembrane transporter activity | biological process | CAV3, ANK2 |
| regulation of calcium ion transport | biological process | BCL2, CATSPER1, IGF1, CACNA2D1, GJA1, CAMK2B, SRI, CXCR4, RCVRN, GNAI2, SLN, CAV3, P2RY12, ANK2, PLN, SLC8A1, OPRD1, IL16, CD4, CAMK2G, GRIN3B, ADORA2A, CXCL12, CACNA1B, AGT, EPB41, RGS4, STIM1 |
| regulation of calcium ion transport into cytosol | biological process | PML |
| regulation of calcium ion-dependent exocytosis | biological process | SYT13, SYT1, SYT5, DOC2A, SYT12, SYT17, SYT6, SYT9, SYT7, SYT2, SYT3, SYT15, RPH3AL, SYT10, TRPV6 |
| regulation of calcium ion-dependent exocytosis of neurotransmitter | biological process | ATP2A2, RAB3GAP1 |
| regulation of calcium-mediated signaling | biological process | RGN, RIT2, GBP1, TMBIM4, TMEM100, BST1, CMKLR1, GPR143, PDK2, PTK2B |
| regulation of CAMKK-AMPK signaling cascade | biological process | HTT, LRRK2 |
| regulation of cAMP-dependent protein kinase activity | biological process | PRKAG2, NPFFR2, MST1, HTT, SESN2, CXCL10 |
| regulation of cAMP-mediated signaling | biological process | GNAI1, PRKAR2A, RASD2, PEX5L, PRKAR2B, PDE10A, PRKAR1B, PDE4A |
| regulation of canonical Wnt signaling pathway | biological process | EMD, CDK14, CCNY, BTRC, PRKN, AMER3, GSKIP, OTULIN, KREMEN1, FZD7, PSEN1, CTNND2, GNAQ, YAP1, FAM53B, DACT1, AMER1, AMER2, DAAM2, ZNF703, WWTR1, GPC3, SOX7, ROR2, ZNRF3, LRRK2, FOLR1 |
| regulation of carbohydrate metabolic process | biological process | MTOR |
| regulation of carbohydrate utilization | biological process | MTOR |
| regulation of cardiac conduction | biological process | DMPK, ACE2, ATP2A2, TRDN, FXYD1, CASQ2, RYR1, RYR2, AHCYL1, FXYD4, ATP1A4, ITPR3, SLC8A3, FXYD3, ABCC9, ATP1A3, ATP1A2, TNNI3K, SLC8A1, FKBP1B, ATP2B3, ASPH, ITPR1, TRPC1, ATP2A3, ATP1B1, NPR1, ITPR2, FXYD2, FXYD6, ATP1A1, ATP1B2, ATP2B1, EHD3, NPPC, NKX2-5, ATP1B3, TMEM65, ATP2A1, NPR2, ATP2B2, CASQ1, SLC8A2, AGT, FXYD7, STIM1 |
| regulation of cardiac muscle cell action potential | biological process | CAMK2D, NOS1AP |
| regulation of cardiac muscle cell action potential involved in regulation of contraction | biological process | ATP2A2, CAMK2D, RANGRF, CAV3, AKAP9, HCN4, CAV1 |
| regulation of cardiac muscle cell contraction | biological process | GATA4, SUMO1, SRI, ATP1A2, ANK2, PDE4B, PLN, PDE4D, KCNJ2, ATP1A1, SCN5A |
| regulation of cardiac muscle cell membrane potential | biological process | ATP2A2, TRDN, FXYD1, SLC9A1, PLN, EHD3, SLC8B1 |
| regulation of cardiac muscle cell proliferation | biological process | MAPK11, BMPR1A, FGF20, TGFBR1, NKX2-5 |
| regulation of cardiac muscle contraction | biological process | RYR2, CAV3, ADRA1A, CALM1, CALM2, CALM3, ANK2, TNNI3K, ASB3, GJA5, EHD3, ADRA1B, P2RX4, NKX2-5, HCN4, SCN10A |
| regulation of cardiac muscle contraction by calcium ion signaling | biological process | ATP2A2, HDAC4, RYR2, SLC9A1, ANK2, SLC8A1, ATP1B1 |
| regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion | biological process | CAMK2D, DMD, CASQ2, RYR2, CACNA1C, TMEM38B, GSTO1, CALM1, CALM2, CALM3, ATP1A2, ANK2, PLN, SLC8A1, FKBP1B, ASPH, HRC |
| regulation of cardiac muscle hypertrophy | biological process | LMCD1 |
| regulation of cardiac muscle tissue development | biological process | JPH2 |
| regulation of cardioblast proliferation | biological process | NOTCH1 |
| regulation of cardiolipin metabolic process | biological process | DNAJC19, PHB2 |
| regulation of cargo loading into COPII-coated vesicle | biological process | SEC24B |
| regulation of cartilage development | biological process | TGFB1, BMP4, SMPD3, KAT2A |
| regulation of catalytic activity | biological process | BCL2, HIF1A, DNMT3L, HSP90AA1, ARHGDIA, DMPK, RIN2, HSPH1, GRPEL1, GPSM2, SH3BP4, PSMD6, PPP1R7, PPP4R1, PSMD1, GDI2, PCP2, MAT2B, PRKAB1, CTSB, RIMS1, CALML6, ARL2BP, CHML, PRKAG2, BAG3, RLN2, CAPN3, COX6A1, CBX8, BMP2K, SCG5, TTN, ANKLE2, EFCAB11, MTMR12, SGK1, KRIT1, PSMD2, SIL1, ATP6V1H, ARHGDIB, CAPN1, CALML4, ARHGDIG, BAG1, CALML5, PSMD3, DPM2, AUP1, PPP1R12B, WAS, RING1, CALML3, COX6A2, PPP1R12C, RALGDS, GRPEL2, PREB, TREX1, RGS12, CPN2, RUNDC3A, GDI1 |
| regulation of cation channel activity | biological process | HOMER1 |
| regulation of cation transmembrane transport | biological process | WNK3, WNK1 |
| regulation of caveolin-mediated endocytosis | biological process | SRC |
| regulation of CD4-positive, alpha-beta T cell activation | biological process | AGER |
| regulation of CD4-positive, alpha-beta T cell differentiation | biological process | SH3RF1, GATA3, ZBTB7B |
| regulation of CD40 signaling pathway | biological process | FANCA, FANCD2, SHARPIN |
| regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation | biological process | RIPK3 |
| regulation of CD8-positive, alpha-beta T cell activation | biological process | CRTAM |
| regulation of CD8-positive, alpha-beta T cell differentiation | biological process | ZBTB7B |
| regulation of CD8-positive, alpha-beta T cell proliferation | biological process | MAPK8IP1, SH3RF1, IRF1 |
| regulation of Cdc42 protein signal transduction | biological process | APOE, RIT2, APOA1, ABL1, NRP1, APOC3 |
| regulation of cell adhesion | biological process | ICAM1, CXCL8, SOX9, IL18, PRLR, PKD1, PTPRJ, CXCR4, PPP1R12A, PPP2CA, SPINK5, STAT5B, C2CD4B, PTK2, KIF14, CBLL2, ROCK2, PRKX, S1PR1, PPP1CB, LAMA4, ROCK1, PKP4, GPR4, ABL1, PML, CBLL1, ABL2, FAF1, CYTIP, CXCR3, SERPINI1, RET, SRF, DLL1, ENG, EPHA8, LAMA3, JAG2, LAMA5, FES, PPP2R1A, FUT2, PTK2B, CYTH1, NUAK1 |
| regulation of cell adhesion mediated by integrin | biological process | PLAU, PTPN11, LPXN, EFNA1, PTK2, ITGB1BP1, LYN, TESC, PIK3CG, EPHA2, EPHA8, CRK, CRKL |
| regulation of cell adhesion molecule production | biological process | FUT7 |
| regulation of cell communication | biological process | GRIN1 |
| regulation of cell communication by electrical coupling | biological process | CAMK2D, SRI, TRDN, CASQ2, SLC8A1, ASPH, GJA5 |
| regulation of cell communication by electrical coupling involved in cardiac conduction | biological process | CAMK2D, SRI, CALM1, CALM2, CALM3, PDE4D, HRC, CAV1 |
| regulation of cell cycle | biological process | BCL2, BAX, BAK1, CCNB2, CCNB1, WEE1, CDC25A, CDC25C, E2F1, ATM, ITGB1, CSNK2A2, STAT3, LEP, PTEN, RB1, SRC, ESX1, MAK, INHA, NANOS3, FOXM1, KIAA0101, GADD45B, HSPA8, RBL1, RBL2, TFDP1, E2F5, COPS5, OVOL2, MOK, GRK5, ADARB1, PUM1, E2F4, PRR11, USP16, CDK14, SFPQ, FBXL22, FBXL12, BTRC, RACK1, MASTL, CDK15, DTL, BCR, FOXA1, CCNI, CABLES1, TSC1, WDR12, CDKL3, L3MBTL1, CCND1, E2F3, CCNDBP1, ID3, CDKL4, LIN54, SIRT2, YY1AP1, PER2, CENPF, TXLNG, PTPRC, GADD45A, E2F2, CCNE1, PLK1, BIRC2, DOT1L, UHRF2, FBXL3, SMIM22, SON, CSNK2A1, CDK6, RBBP4, EP300, SKP2, MS4A3, GAS2L1, HIPK2, CDKL5, UBA3, CDK19, BEX2, E2F6, ABL1, SFN, FOXG1, CDK18, LIN52, JUNB, CTBP1, TFDP2, LIN37, CABLES2, CCNG1, CCNG2, MNT, RGCC, CLIC1, RAD51D, CDKN1A, CDK3, CDKL1, CDK20, E2F7, E2F8, IRF1, CCNF, CDKL2, MX2, MECOM, MADD, SPIN2A, ZNF703, CDK12, ARNTL, PES1, CCNE2, TSC2, CDK17, PHACTR4, JUND, LIN9, FIGNL1, BAP1, PRDM11, CCND3, NUP214, SRSF5, PSMG2, TP53 |
| regulation of cell cycle arrest | biological process | FOXM1, SLC25A33, NEUROD1, SDE2, CDK5, AKT2, BIN1 |
| regulation of cell cycle checkpoint | biological process | AKT1 |
| regulation of cell cycle G1/S phase transition | biological process | TRIM39, FBXW7, PLPP2, TAF1, CDKN1B, CDKN1A |
| regulation of cell cycle G2/M phase transition | biological process | TP53, NEK10, PLK1, GTSE1, PAXIP1 |
| regulation of cell cycle phase transition | biological process | DBF4, SIX3, DBF4B |
| regulation of cell cycle process | biological process | SOX9, USP51, HMGA2, INSM2, TXLNG, INSM1, E4F1, RPRD1B, SND1, ANKK1 |
| regulation of cell death | biological process | HSPA1A, HSPA1B, ING1, CRYAB, YWHAZ, EEF1D, SLC25A24, MAP3K5, CLNK, NOA1 |
| regulation of cell diameter | biological process | PLEK |
| regulation of cell differentiation | biological process | LIF, SOX9, FGFR1, CTNNB1, BMP4, NRG1, RAF1, GLI3, EID1, KLF4, PPP2CA, BCL6, TCFL5, ST7, SPOCK2, WNT3A, RUNX1, TFAP2A, BIRC2, APC, PLEKHB2, BCL6B, POU3F2, SPRY2, RUNX2, PTBP3, FADS1, PLEKHB1, APC2, RHOH, FES, PPP2R1A, SIK1, TBX19, LTBP4, KLK6, SOCS3 |
| regulation of cell differentiation involved in embryonic placenta development | biological process | STK3, STK4, GCM1 |
| regulation of cell division | biological process | CIB1, RBL1, RBL2, EFHC1, RACK1, PLK3, DLL1, KIF18B, FSD1 |
| regulation of cell fate commitment | biological process | FGFR2, BMP4, PAX7, GDF3 |
| regulation of cell growth | biological process | CD320, DDR1, FOXM1, CAMK2D, ITCH, TSG101, CISH, SOCS2, NUBP1, NRG3, CHPT1, BLZF1, ATAD3A, ARHGEF11, XBP1, KIAA1109, OGFR, KIF14, EPB41L3, CREB3, TFRC, WFDC1, TAOK2, ROS1, BCAR1, SGK2, FBLN5, PRKCQ, RASGRP2, PAPPA2, AGTR1, IGFBP7, PTCH2, CDC73, PLCE1, URI1, IGFBP4, TMEM97, SGK1, SGK3, EBAG9, MAD2L2, SPOCK1, LAMTOR1, KAZALD1, RAB33B, ILK, PAK4, CEACAM1, EGLN2, CLSTN1, LMX1A, IGFBP5, PAK5, MUC12, MELTF, TMC8, RPTOR, FAM107A, CDK11B, NET1, LTBP4, BAP1, CLSTN3, CDK11A, AGT, CRKL |
| regulation of cell growth by extracellular stimulus | biological process | PPP1R9B, MYOCD, KIF26A |
| regulation of cell junction assembly | biological process | RAP1A, TJP1, RAPGEF2, ROCK2, ROCK1, RAPGEF1, RAP1B |
| regulation of cell maturation | biological process | KIF14 |
| regulation of cell migration | biological process | TGFB1, AKT1, TMSB4X, KIF2A, RTN4, BEX4, ENPP2, TMSB15A, TMSB15B, NCK1, DPYSL3, PHLDA2, TMIGD1, PLXNC1, NEXN, KIF14, MACF1, PRKX, ROBO4, AJUBA, NOTCH1, LAMA4, AMOT, RCC2, TMSB4Y, NTN1, ROCK1, TTBK2, MEAK7, AMOTL2, UNC5C, TMSB10, RAC1, MYSM1, SPATA13, PLXNA1, OSGIN1, SGK1, HACE1, SGK3, SLK, VCL, PARD6B, PLXNA4, LDB1, TBCCD1, CEACAM1, ADGRG3, SST, CDK5, PLXNB3, LDB2, THY1, PECAM1, FUT3, LAMA3, FRMD5, LAMA5, PLXNA3, PLXNB2, PLXNB1, PLXNA2, AKT2, PLXND1, MINK1, SRCIN1, CAMSAP3, EDN3, MGAT3, PTK2B, AMOTL1, DOCK10, ABI3 |
| regulation of cell migration involved in sprouting angiogenesis | biological process | FBXW7, FGF2 |
| regulation of cell morphogenesis | biological process | ZMYM1, CAMSAP1, ZMYM2, QRICH1, PDZD8, AGO4, ZMYM3, PHIP, EFNA5, ZMYM5, BCL9L, FMNL2, WTIP, CAPZB, ZMYM4, ZRANB1, RAC3, ZMYM6, SH3D19, CLDN4 |
| regulation of cell morphogenesis involved in differentiation | biological process | CNTN2 |
| regulation of cell motility | biological process | EGFR, EGF, ERBB2, NRG1, RAF1, CD81, INPP5F, ROCK2, NRG4, DIAPH1, ROCK1, PKN2, EREG, CDK6, NRG2, ARHGAP18, ABL1, SSX2IP, ABL2, HBEGF, ERBB3, BTC, PKN1, CCDC125, CRK, FES, PRAG1, MEMO1 |
| regulation of cell motility involved in somitogenic axis elongation | biological process | PPP2R3A, NKD1 |
| regulation of cell projection assembly | biological process | SRC, CCL19, FAM110C |
| regulation of cell projection organization | biological process | SEMA4D, PIFO |
| regulation of cell projection size | biological process | WNT7B |
| regulation of cell proliferation | biological process | NR5A2, EGFR, TGFB1, TNF, IL6, TGFB3, TNFRSF1A, TNFRSF1B, PTGS1, FAS, PTGS2, BRCA1, SOX9, HIF1A, DNMT1, TYK2, EZH2, CIB1, MBD2, GHRL, FGFR1, CTNNB1, BAG6, IGF1, YES1, KIT, SRC, MIF, NOS2, BMPR2, PLAU, FOXO1, SHH, INHA, NF2, S100A11, FOXM1, TNFRSF25, ACE2, FANCA, RBFOX2, GLI3, HOXD13, TCF7, KLF4, PIAS1, E2F4, XIAP, TXNIP, DUSP22, BEX4, SHC1, BCL6, SMAD4, PPP1R9B, DUSP15, ALK, RAPGEF2, CXCL11, LTK, CTNNA1, STAT5B, PURA, PPARD, TMIGD1, GNL3, SAT1, PTK2, TCFL5, CREB3, TFRC, ANXA1, IL9R, EPS15, CCDC88A, BIRC7, MAFG, NOTCH1, NKX2-3, SGK2, FANCL, MITF, PRDM1, PTGER2, PKD2, JARID2, TIMELESS, PF4, AGTR1, PLCD1, PDX1, TNFRSF9, PID1, SCGB3A1, SRMS, TPD52L2, NFKBIA, ASCL1, BID, SQLE, MEAK7, CHRNA10, AMBN, TFAP2A, BIRC2, SMIM22, PBX1, TGFB2, CDK6, HP1BP3, MAP11, MENT, SAV1, SIX3, CDKN1B, TNK1, KSR1, BCL6B, OSGIN1, SGK1, ABL1, FER, RBPJ, FA2H, ARHGEF2, SGK3, PDS5B, CFDP1, LYN, JUNB, TNC, RPA3, PLA2G4A, RNF126, BIRC6, TES, YAP1, IER5, TBX3, ESRRA, STAT2, TFAP2E, SPRY2, FGR, ERBB3, AVPR1B, SFRP2, LHX5, TGFBR2, SLA, NDRG1, HCK |
| regulation of cell proliferation involved in tissue homeostasis | biological process | SOX9 |
| regulation of cell shape | biological process | IL6, ICAM1, VEGFA, KDR, BRWD1, HEXB, KIT, CDC7, FN1, EZR, TPM1, WIPF3, SEMA3E, RASA1, SHROOM3, MYH10, BAMBI, FERMT2, BAIAP2, ANXA7, CDC42EP5, ARAP1, WASF3, RHOU, MYH14, MYL12B, ZMPSTE24, PTN, BVES, SLC9A3R1, WIPF1, PLXNC1, WDR1, CCL3, PTK2, DLC1, EPB41L3, ANXA1, EPB42, CCL11, PHIP, ARHGAP35, TAOK2, RHOG, SEMA4D, HPN, DIAPH1, SLC26A5, CDC42EP2, ALDOA, CDC42EP3, PRPF40A, CDC42EP4, RHOQ, CDC42EP1, GNA12, EPS8, DLG1, FGD6, RHOBTB3, MSN, RAC1, PALM2, ARHGAP18, CDC42SE2, PLXNA1, RAC2, PLEKHO1, CYFIP1, FMNL2, CFDP1, F11R, RDX, FBLIM1, PLXNA4, MYO10, PARVA, CFAP410, S100B, LPAR1, FGD4, TBCCD1, LST1, ATP10A, ITGB2, FGR, P2RY1, PDPN, PALM, RAC3, TIGD5, FGD2, WIPF2, LIMD1, HCK, WAS, CCL7, DMTN, ARHGAP15, FAM171A1, RHOJ, CDC42SE1, PLXNB3, CORO1A, MYH9, CRK, ITGA7, BRWD3, RHOV, GAS2, PLXNA3, PLXNB2, PLXNB1, PLXNA2, F2, FES, CSF1R, ARHGEF18, PRAG1, PLXND1, EPB41, PTK2B, FGD5, SH3KBP1, COCH, FMNL1, VIL1, S100A13, STRIP2, CCL2, FMNL3 |
| regulation of cell size | biological process | EZR, E2F4, LAMTOR5, VAV3, SLC9A3R1, IQGAP3, LARS1, WDTC1, MSN, RAC1, IL7R, VAV2, RDX, KEL, RARG, VAV1, RPTOR, RAP1GAP2 |
| regulation of cell-cell adhesion | biological process | SRC, WNT4, EFNA5, CELSR2, ZDHHC2, NRARP, LEF1, PODXL, FUT7, EPHA7, ADAM8, RHOH, EPHB3, MINK1 |
| regulation of cell-cell adhesion mediated by integrin | biological process | DPP4, ADA, FERMT3 |
| regulation of cell-matrix adhesion | biological process | BCL2, DDR1, TSC1, EMP2, ONECUT2, BST1, ONECUT1, THY1, MINK1, NF1, MYOC |
| regulation of cell-substrate adhesion | biological process | ATXN3, RSU1, RAC2, MYADM |
| regulation of cellular amino acid metabolic process | biological process | PSMA3, OAZ3, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, PSMD6, PSMD1, PSMD14, PSMD7, PSMB6, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, ODC1, NQO1, PSMB8, PSMD4, PSMC3, PSMA6, AZIN1, PSMD12, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, OAZ1, OAZ2, PSMD5, PSMF1, PSMB3, PSMD3, PSMC1, INS, PSMD13, PSMB10 |
| regulation of cellular carbohydrate catabolic process | biological process | SCARB2 |
| regulation of cellular component movement | biological process | ARAP1 |
| regulation of cellular component organization | biological process | STK38L, COL5A1 |
| regulation of cellular component size | biological process | PTEN |
| regulation of cellular extravasation | biological process | BST1 |
| regulation of cellular hyperosmotic salinity response | biological process | EFHD1, MICU1, LETM1, SLC25A23 |
| regulation of cellular ketone metabolic process | biological process | PDK4, NCOR2, PPARA, PDK2 |
| regulation of cellular localization | biological process | PTEN, CAMK2D, PARD3, PARD6A, PARD6B, KIAA1614, PARD6G |
| regulation of cellular metabolic process | biological process | HEXB, TBK1, STING1, TREX1 |
| regulation of cellular pH | biological process | LACC1, MAFG, ATP1A4, ATP6AP1, SLC4A10 |
| regulation of cellular process | biological process | WNK4, WNK1 |
| regulation of cellular protein catabolic process | biological process | WDR91 |
| regulation of cellular protein localization | biological process | PARP1, CSNK1E, DVL1, CCNE1, MAP2, DVL3, CCNE2, TRIM67, TRIM46 |
| regulation of cellular protein metabolic process | biological process | CNDP1, PM20D2, SSH1, VPS35 |
| regulation of cellular respiration | biological process | NOS2, PIK3CA, PNPT1, CISD1, PRDM16, TREX1, SLC25A23, NOA1 |
| regulation of cellular response to drug | biological process | HMGA2, NCOA1 |
| regulation of cellular response to growth factor stimulus | biological process | DMD |
| regulation of cellular response to heat | biological process | FKBP4, HSP90AA1, MAPK3, MAPK1, GSK3B, HSF1, ATM, MTOR, ATR, HSPA1A, HSPA1B, HSPA1L, HSPA8, CAMK2B, CAMK2D, NUP93, HSPH1, CHORDC1, PTGES3, HIKESHI, NUP37, NUP88, NUP85, RPA2, NUP107, NUP43, POM121, NUP35, NUP58, CRYAB, SEC13, NUP205, DNAJC7, NUP50, NUP62, BAG4, RPA1, CREBBP, NUP155, BAG3, BAG5, NUP153, RAE1, SEH1L, HSBP1, YWHAE, EP300, CCAR2, NUP133, DNAJC2, RPA3, NUP54, TPR, DNAJB1, RANBP2, NUP98, HSPB8, BAG1, MLST8, CAMK2G, AAAS, AKT1S1, RPTOR, NUP210, NUP188, CAMK2A, NUP42, NUP214, NUP160 |
| regulation of cellular response to hypoxia | biological process | HIF1A, CHCHD2, ROCK2, AJUBA |
| regulation of cellular response to insulin stimulus | biological process | USO1, GPLD1, ATP2B1 |
| regulation of cellular response to manganese ion | biological process | SLC30A10 |
| regulation of cellular response to osmotic stress | biological process | CLN3 |
| regulation of cellular response to oxidative stress | biological process | PRKN, PINK1, FUT8, MAPKAP1, ALOX5, ABCD1 |
| regulation of cellular response to stress | biological process | DYRK3, CRHBP, SLC38A2, ADCY8, CORO2B |
| regulation of cellular response to X-ray | biological process | GATA3 |
| regulation of cellular senescence | biological process | ZMPSTE24, BMPR1A, ING2, ZNF277, ABL1, PNPT1, NEK4, ARNTL, NEK6, VASH1, RSL1D1, NUAK1, TP53 |
| regulation of centriole replication | biological process | NPM1, PLK2, C10orf90, ALMS1, CEP295, STIL, SPICE1 |
| regulation of centriole-centriole cohesion | biological process | CTNNB1, CEP250 |
| regulation of centromere complex assembly | biological process | RB1, H3-3A |
| regulation of centromeric sister chromatid cohesion | biological process | CTNNB1, AXIN2 |
| regulation of centrosome cycle | biological process | MCPH1, MARK4 |
| regulation of centrosome duplication | biological process | CHORDC1, CHMP2A, NPM1, CHMP5, XPO1, VPS4B, CHMP4B, CEP131, CHMP1A, GEN1, PDCD6IP, CHMP4C, PKHD1, FBXW5, XRCC3, CHMP3, CHMP1B |
| regulation of ceramide biosynthetic process | biological process | SAMD8 |
| regulation of cGMP metabolic process | biological process | VEGFA |
| regulation of cGMP-mediated signaling | biological process | PTK2B |
| regulation of chaperone-mediated autophagy | biological process | EEF1A1, ATP13A2, CTSA, EEF1A2, GFAP |
| regulation of chaperone-mediated protein folding | biological process | DNAJB2 |
| regulation of chemokine (C-X-C motif) ligand 2 production | biological process | FOXP1, MCOLN2 |
| regulation of chemokine production | biological process | CXCL6, ACKR1, ZFPM1 |
| regulation of chemotaxis | biological process | CXCR4, USP14, ADGRA2, P2RY12, EFNB2, PDGFRA, P2RX4 |
| regulation of chloride transport | biological process | CA2, CA7 |
| regulation of cholesterol biosynthetic process | biological process | APOB, SCD, IDI1, SCAP, FDFT1, SREBF2, LSS, PMVK, ELOVL6, SC5D, MBTPS1, HMGCR, HMGCS1, SEC14L2, SQLE, FASN, NFYC, RAN, NFYA, MBTPS2, GPAM, NFYB, SREBF1, ACACA, CYP51A1, TM7SF2, DHCR7, MVD, ACACB, MVK, ABCA2 |
| regulation of cholesterol efflux | biological process | TTC39B, YJEFN3, LAMTOR1, CETP |
| regulation of cholesterol esterification | biological process | ABCG1, LAMTOR1, ABCA2 |
| regulation of cholesterol homeostasis | biological process | NR1H3 |
| regulation of cholesterol import | biological process | LAMTOR1 |
| regulation of cholesterol metabolic process | biological process | EPHX2, ARV1, GNB3, DGAT2, LDLR, POR, ACADVL, TTC39B, NR1H4, ACADL, DGKQ, SERPINA12, LMF1 |
| regulation of cholesterol transport | biological process | OSBPL6, APOC1, LRP1 |
| regulation of cholesterol transporter activity | biological process | PPARG |
| regulation of chondrocyte development | biological process | RFLNB, AXIN2, RFLNA |
| regulation of chondrocyte differentiation | biological process | CCN2, SCIN, MDK, MAF, GLG1, TRPS1, SIX2, PTHLH, HOXA11, LNPK |
| regulation of chorionic trophoblast cell proliferation | biological process | BOK, FZD5 |
| regulation of chromatin assembly | biological process | SPTY2D1, PARP10 |
| regulation of chromatin assembly or disassembly | biological process | TLK2, TLK1 |
| regulation of chromatin disassembly | biological process | PADI2, MAP1S |
| regulation of chromatin organization | biological process | HNRNPU, MKI67, MLLT3, SETD5, SSRP1, ALKBH4, SETD1A, METTL4 |
| regulation of chromatin silencing | biological process | HIRA |
| regulation of chromatin silencing at telomere | biological process | CDC45 |
| regulation of chromosome condensation | biological process | CCNB1, WAPL, MCPH1 |
| regulation of chromosome organization | biological process | CENPV |
| regulation of chromosome segregation | biological process | PUM2, PUM1, BUB3, WAPL, BUB1, ZNF207, MKI67, KIF2B, MAGEA5, AURKB |
| regulation of chromosome separation | biological process | CSNK2A1 |
| regulation of chronic inflammatory response | biological process | CCL5 |
| regulation of cilium assembly | biological process | ODF2, IFT88, TBC1D15, EVI5, USP6NL, TBC1D19, DYNC2LI1, TBC1D1, RABGAP1, TBC1D20, TBC1D10C, TBC1D22B, DCDC2, SDCCAG8, ATG5, TBC1D13, CYLD, CDKL5, TBC1D8, TBC1D22A, TBC1D10B, ATG3, CDKL1, TBC1D9B, TBC1D16, CNTROB, SYNE2, TBC1D5, MAPK15, SGSM3, TBC1D2, TBC1D17, TBC1D14, TBC1D24, TCTEX1D2 |
| regulation of cilium beat frequency | biological process | DNAH11, ARMC4, DNAAF1, CCDC40 |
| regulation of cilium beat frequency involved in ciliary motility | biological process | CATSPER1, BBS2, MKKS, BBS4, GAS2L2, CFAP20, CCSAP |
| regulation of cilium movement | biological process | CCDC65, CFAP298, DRC1 |
| regulation of circadian rhythm | biological process | EZH2, MAPK8, PPARG, TOP2A, CREM, NR1H3, UBE3A, NR1D2, PER1, PSPC1, MAGEL2, SIAH2, SFPQ, HNRNPD, FBXW7, BTRC, MAGED1, CSNK1E, ROCK2, PPARGC1A, BHLHE40, PPP1CB, NONO, TIMELESS, PER2, RORA, CSNK1D, FBXL3, CCAR2, MAPK9, PRKDC, KLF10, USP7, KDM2A, PML, CRY1, PRKAA2, USP9X, HDAC3, NR1D1, HNF4A, ID2, PROX1, PRKCG, PPARA, CRY2, OPN4, MAPK10, SPSB4, DRD4, DDB1, OPN3 |
| regulation of circadian sleep/wake cycle | biological process | NR1D1 |
| regulation of circadian sleep/wake cycle, non-REM sleep | biological process | IL6, KCNA2, CHRNB2 |
| regulation of circadian sleep/wake cycle, REM sleep | biological process | CHRNB2 |
| regulation of circadian sleep/wake cycle, sleep | biological process | PTGDS, PER3, NMU, ADA, DRD3, ADRB1 |
| regulation of clathrin-dependent endocytosis | biological process | SH3GL2, SH3GL3, BMP2K, SNAP91, AAK1, SMAP1, DNAJC6, PROM2, HIP1R |
| regulation of cobalamin metabolic process | biological process | CLYBL |
| regulation of cohesin loading | biological process | RB1, WAPL, HDAC8, CDCA5 |
| regulation of cold-induced thermogenesis | biological process | SLC25A44 |
| regulation of collagen catabolic process | biological process | ITGB1 |
| regulation of collagen fibril organization | biological process | AEBP1 |
| regulation of collagen metabolic process | biological process | MFAP4 |
| regulation of collateral sprouting | biological process | FSTL4 |
| regulation of complement activation | biological process | C3, CD46, C1QBP, C1QB, CD55, CD81, CFHR1, C6, CD59, C4BPB, C5, CFH, C1S, SUSD4, PROS1, CR1L, PHB2, CFB, C1QC, CFP, CR2, C3AR1, VTN, C5AR2, C1R, C1QA, SERPING1, C2, F2, CD19, CFI, C8G, C7, CPN2, CFHR5, C5AR1 |
| regulation of complement-dependent cytotoxicity | biological process | IL11, IL10, CD55, CD59, CFH, CR1L, TGFB2 |
| regulation of COPII vesicle coating | biological process | SAR1A, SAR1B, MAPK15, PREB |
| regulation of copper ion transmembrane transport | biological process | SLC31A2 |
| regulation of core promoter binding | biological process | CTNNB1 |
| regulation of corticosterone secretion | biological process | CRHR1, POMC |
| regulation of corticotropin secretion | biological process | CRHBP |
| regulation of corticotropin-releasing hormone secretion | biological process | HTR2C |
| regulation of cortisol biosynthetic process | biological process | H6PD, DGKQ |
| regulation of cristae formation | biological process | OMA1 |
| regulation of cyclase activity | biological process | GRM7 |
| regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | CDC25A, CDC25C, PTEN, CCNA2, DIRAS3, CCNC, CDKN3, GTPBP4, BCCIP, CDK7, CCNYL1, CDK5RAP1, CCNH, CCNY, CCNT1, CCNJL, CCNI, CDK5RAP3, CCNQ, CCND1, CDKN2B, CDKN2D, CDC6, GADD45A, CCNE1, CCNK, CDK5R1, GTF2H1, CDKN1B, CCNL2, CNPPD1, SFN, CDKN2C, CCNG1, CCNG2, CCNL1, CDKN1A, BLM, CDK5R2, CCNF, PKMYT1, MNAT1, CCNE2, CCNP, CCNO, SERTAD1, CCND3, HERC5, CDC37, CCNB3 |
| regulation of cysteine-type endopeptidase activity | biological process | BIRC2, PSMB9 |
| regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological process | FAS, BAX, MGMT, BAD, NGF, SOX2, TP63, BEX3, NLRP12, EPHA7, PYCARD, NGFR, DELE1 |
| regulation of cytochrome-c oxidase activity | biological process | SPHK2, TACO1, PHB2, ATP7A |
| regulation of cytokine activity | biological process | GREM2 |
| regulation of cytokine biosynthetic process | biological process | IGF2BP2, GATA3, MAP2K3, IGF2BP3, IGF2BP1 |
| regulation of cytokine production | biological process | LTF, ACE2, IQGAP1, BCL6, ZBTB6, ELF1, JPH4, ANKRD2, TRAF3, ZBTB20, MOG, BTN3A1, ZBTB37, LRRC19, ZBTB32, BTN3A2, BCL6B, ZBTB26, LITAF, F11R, LYN, BTNL9, HHLA2, BTN3A3, ERMAP, SFTPD, VTCN1, ZBTB45, ICOSLG, BTNL3, ZBTB34, ZNF131, BTNL8 |
| regulation of cytokine production involved in immune response | biological process | ATG5 |
| regulation of cytokine production involved in inflammatory response | biological process | LEP, NOS2, MAPK14, PER1, PLD4, ALOX5, PLD3, BAP1 |
| regulation of cytokine secretion | biological process | TLR4, TLR2, SOCS1, TLR1, TLR10, LYN, GPAM, TLR9, TLR5, CCN4, TLR6 |
| regulation of cytokine-mediated signaling pathway | biological process | IRAK1, IRAK2, ELF1, CBFB, RUNX1, IL3, LIFR |
| regulation of cytokinesis | biological process | BRCA2, KIF20A, CETN2, RAB11A, PLK2, CCP110, PIN1, SH3GLB1, ENTR1, RAB11FIP4, PRC1, PIK3C3, BBS4, GIT1, PRPF40A, CALM1, CALM2, CALM3, PLK1, BECN1, AHCTF1, KLHL21, PIK3R4, BIRC6, UVRAG, FLCN, BCL2L1, ZFYVE26, PLK3, PDXP, RAB11FIP3, AURKB, FSD1, KIF13A, KLHL9, KLHL13 |
| regulation of cytokinesis, actomyosin contractile ring assembly | biological process | ECT2 |
| regulation of cytoplasmic mRNA processing body assembly | biological process | ATXN2L, ATXN2 |
| regulation of cytoplasmic translation | biological process | ZNF385A |
| regulation of cytoplasmic translational fidelity | biological process | AARS1 |
| regulation of cytoskeleton organization | biological process | MAPK3, MAPK1, DYNLT1, S100A9, STMND1, TJP1, CAPN2, MARK2, PTK2, NEXN, ARHGEF5, CLIC4, STMN1, STMN3, DIAPH1, F11R, MYCBP2, TAOK1, CNTRL, S100A8, CLN3, SPEF1, PLXNB1, AFAP1 |
| regulation of cytosolic calcium ion concentration | biological process | CALB2, FZD9, TRPC3, RYR1, RYR2, HCRTR1, CALB1, PDE6A, CAV3, CAV2, YWHAE, TRPC7, PLN, ADCY8, TMEM64, FKBP1B, ATP2B3, BOK, TRPC1, CLN3, CALCA, TRPC5, CALCB, ATP2B1, TRPC4, HRC, TMEM178A, CNGB1, F2, PDE6B, ATP2B2, SLC8B1, CDH23, SLC8A2, CAV1, GPER1 |
| regulation of D-erythro-sphingosine kinase activity | biological process | EEF1A1 |
| regulation of defense response to bacterium | biological process | FOXP1 |
| regulation of defense response to virus | biological process | ZMPSTE24, TRAF3, IFIT1, IL27, ELMOD2, TSPAN32, HERC5 |
| regulation of defense response to virus by host | biological process | IL15, RNF216 |
| regulation of defense response to virus by virus | biological process | B2M, PACS1, AP2S1, AP1G1, AP1S2, AP1S1, AP2A2, ARF1, AP2M1, AP1S3, CD247, RAC1, AP2B1, ATP6V1H, AP1B1, CD4, HCK, LCK, CD28, AP2A1, AP1M1, CD8B, ELMO1, DOCK2 |
| regulation of definitive erythrocyte differentiation | biological process | RBFOX2, SENP1, ZFPM1, GATA1 |
| regulation of delayed rectifier potassium channel activity | biological process | KCNAB1, KCNG1, KCNE1 |
| regulation of dendrite development | biological process | CDC20, BCL11A, CAMSAP2, CAMK1D, CSMD3, RTN4IP1, CDKL5, MFSD2A, SS18L1, KNDC1, PREX1, CRK, RAB17, SEZ6, MARK1, CRKL |
| regulation of dendrite morphogenesis | biological process | GSK3B, NSMF, HECW2, GRIN1, SDC2, SEMA4D, SARM1, NEDD4, ADGRB3, CHRNA3, NEDD4L, TNIK, HECW1, PQBP1, KNDC1, RAP2A, LZTS1, CHRNB2 |
| regulation of dendritic cell cytokine production | biological process | TLR4, TLR3 |
| regulation of dendritic cell dendrite assembly | biological process | CCR7 |
| regulation of dendritic cell differentiation | biological process | HLA-B |
| regulation of dendritic spine development | biological process | FMR1, CAMK2B, TANC2, PPFIA2, DISC1, MEF2C, CPEB3, ARF6, KIF1A, SDK1 |
| regulation of dendritic spine maintenance | biological process | FCGR2B, ABHD17B, HOMER1, VPS35 |
| regulation of dendritic spine morphogenesis | biological process | TANC2, PPFIA2, ABI2, ARHGAP33, DNM3, CDK5R1, EPHA4, PDLIM5, PPP1R9A, CDK5, KIF1A, LZTS3, SRCIN1, ARHGAP44, LRRK2 |
| regulation of dense core granule exocytosis | biological process | BAIAP3 |
| regulation of dephosphorylation | biological process | SMG7, SMG6, IGBP1, SMG5 |
| regulation of development, heterochronic | biological process | HMGN1 |
| regulation of developmental growth | biological process | NIPBL |
| regulation of developmental pigmentation | biological process | BCL2, KIT, ADAMTS20, BCL2L11, ADAMTS9, VPS33A, EDN3 |
| regulation of developmental process | biological process | NOTCH1, NOTCH4, NOTCH3 |
| regulation of diacylglycerol biosynthetic process | biological process | AVIL |
| regulation of digestive system process | biological process | OXTR, OXT |
| regulation of DNA binding | biological process | TGFB1, CSNK2B, PAX7, BCL3, HJURP, TAF10, AGER |
| regulation of DNA biosynthetic process | biological process | TFDP1, PDGFA, TOM1L1, CDKN1A |
| regulation of DNA damage checkpoint | biological process | RPA2, RNASEH2B, FEM1B, FBXO4, RFWD3, WDR76, CRY1, ETAA1 |
| regulation of DNA damage response, signal transduction by p53 class mediator | biological process | ZMPSTE24, SMYD2, TP53, KMT5A |
| regulation of DNA double-strand break processing | biological process | WDR70, HELB |
| regulation of DNA endoreduplication | biological process | SENP2 |
| regulation of DNA helicase activity | biological process | POT1 |
| regulation of DNA methylation | biological process | BRCA1, MBD1, ZMPSTE24, MIS18A, H1-8, RLF, MBD3, KDM1B |
| regulation of DNA N-glycosylase activity | biological process | TDG |
| regulation of DNA recombination | biological process | KPNA2, THOC1, ALYREF, IL7R, KPNA1, SMARCAD1 |
| regulation of DNA repair | biological process | USP1, CDK9, POLH, UBE2N, UBE2V1, UBE2V2, WRNIP1, SIRT7, PARG |
| regulation of DNA replication | biological process | PCNA, ORC5, PPP2CA, SMC3, RBBP6, OBI1, EHMT2, CCDC88A, USP37, DSCC1, ORC3, ID3, ANKRD17, ESCO1, ZBTB38, ACVRL1, PPP2R1A |
| regulation of DNA stability | biological process | RTF2, DDI1 |
| regulation of DNA strand resection involved in replication fork processing | biological process | ZNF365 |
| regulation of DNA-dependent DNA replication | biological process | BLM |
| regulation of DNA-dependent DNA replication initiation | biological process | NBN, WDR18, WRNIP1 |
| regulation of DNA-templated transcription in response to stress | biological process | BCLAF1, RELA, RPS6KA1, RGS14 |
| regulation of DNA-templated transcription, elongation | biological process | THOC1, HTATSF1, ERCC6, SUPT5H, ELOA2, CCAR2, SETD5, TSFM, ZNF326, TCEA2 |
| regulation of DNA-templated transcription, initiation | biological process | RRN3 |
| regulation of dopamine metabolic process | biological process | TACR3, PRKN, PNKD, NR4A2, PDE1B, DRD1, CHRNB2, SLC6A3, DRD4 |
| regulation of dopamine receptor signaling pathway | biological process | ALK, DTNBP1, RGS8, LRRK2 |
| regulation of dopamine secretion | biological process | SYT13, SNCA, PRKN, SYT1, SYT5, DTNBP1, SYT12, FGF20, DRD3, CHRNA6, SYT17, HTR1B, KCNA2, SYT6, SYT9, CHRNB2, CHRNA4, DRD2, SYT7, SYT2, SYT3, SYT15, SYT10, SNCG |
| regulation of dopamine uptake involved in synaptic transmission | biological process | GDNF, DRD3, DRD1, DRD2 |
| regulation of dopaminergic neuron differentiation | biological process | DKK1, TIAM1 |
| regulation of dosage compensation by inactivation of X chromosome | biological process | RLIM |
| regulation of double-strand break repair | biological process | UBR5, TRIP12, DEK, PML |
| regulation of double-strand break repair via homologous recombination | biological process | TEX15, TERF2IP, RPA2, SHLD2, USP51, RTEL1, PPP4R2, PPP4C, SIRT6, RAD51AP1, FIGNL1, SPIDR, ZNF365 |
| regulation of double-strand break repair via nonhomologous end joining | biological process | DEK, POT1, USP51, NSD2, SHLD1, ACTR2, SIRT7, WAS, MRNIP |
| regulation of early endosome to late endosome transport | biological process | MAPK3, MAPK1, SRC, MAP2K2, MAP2K1, DENND10, CHMP3 |
| regulation of eIF2 alpha phosphorylation by amino acid starvation | biological process | IMPACT |
| regulation of eIF2 alpha phosphorylation by dsRNA | biological process | NPM1 |
| regulation of eIF2 alpha phosphorylation by heme | biological process | EIF2AK1 |
| regulation of embryonic cell shape | biological process | 39326, DAG1, SEPTIN7 |
| regulation of embryonic development | biological process | CDK1, NFE2L2, INSR, TRIP12, DHX36, PHLDA2, TDG, LAMA4, RAB14, EHMT1, NIPBL, LAMA3, LAMA5, CCSAP |
| regulation of enamel mineralization | biological process | MMP20 |
| regulation of endocannabinoid signaling pathway | biological process | ABHD6, MGLL, CAMK2A |
| regulation of endocytic recycling | biological process | BVES, INPP5F, NDRG4, PLA2G3, RAB11B |
| regulation of endocytosis | biological process | AP2S1, RAB4A, RUFY1, ZFYVE16, RAB20, PICALM, ARFGAP1, RIT2, EHD4, PACSIN2, RUFY2, ABL1, SNX12, STON1, PTPN1, ABL2, RAB4B, OPHN1, RAB5B, CDH13, CD22, TSC2, PACSIN3, HIP1R, SNX17, BIN1, STON2, PACSIN1, SYNJ2BP |
| regulation of endodeoxyribonuclease activity | biological process | NPM1 |
| regulation of endodermal cell fate specification | biological process | HNF1B, DUSP6, DKK1 |
| regulation of endopeptidase activity | biological process | PSMA3, PSMB8, ATP13A2, NRDC, FURIN, ABCA2, A2ML1 |
| regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation | biological process | EIF2AK3 |
| regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | HERPUD1, EIF2AK3 |
| regulation of endoplasmic reticulum tubular network organization | biological process | ARL6IP1, TMEM33 |
| regulation of endoribonuclease activity | biological process | NPM1 |
| regulation of endosome organization | biological process | SCARB2 |
| regulation of endosome size | biological process | ALS2, RAB5A |
| regulation of endothelial cell apoptotic process | biological process | TEK, TNF |
| regulation of endothelial cell chemotaxis to fibroblast growth factor | biological process | FGF2, FGF1 |
| regulation of endothelial cell differentiation | biological process | APOLD1, CEACAM1 |
| regulation of endothelial cell migration | biological process | PTN, PTK2, EMP2, GLUL, CEACAM1, RHOJ, BMPER, PDPK1 |
| regulation of endothelial cell proliferation | biological process | LEP, ALDH1A2, ANGPT1, FGF18, ACVRL1, FUT2 |
| regulation of endothelial tube morphogenesis | biological process | FOXP1, FGF1, ADAMTS12, CXCL10 |
| regulation of energy homeostasis | biological process | LEPR, FOXO1 |
| regulation of entry of bacterium into host cell | biological process | FUCA2, EXOC7, EXOC2, CAV1 |
| regulation of ephrin receptor signaling pathway | biological process | ANKS1A |
| regulation of epidermal cell differentiation | biological process | KEAP1, MAFG, MAFF, KLF7 |
| regulation of epidermal cell division | biological process | TP63, SFN, KDF1 |
| regulation of epidermal growth factor receptor signaling pathway | biological process | RHBDF1, IFI6, FER, MVB12A, WDR54, CEACAM1, CDH13, PTPN12, RHBDF2, MVB12B |
| regulation of epidermal growth factor-activated receptor activity | biological process | APP, SHC1, NCK2, PSEN1 |
| regulation of epidermis development | biological process | NAB1, NME2, NAB2, SGPP1 |
| regulation of epithelial cell differentiation | biological process | PRLR, CTNNB1, XDH, FOXJ1, STAT5B, KIAA1109, GATA3, ASCL1, ALOX15B |
| regulation of epithelial cell differentiation involved in kidney development | biological process | PRKX |
| regulation of epithelial cell migration | biological process | SRC, CORO1C, PTK2, MACF1, ARSB, SASH1 |
| regulation of epithelial cell proliferation | biological process | EDNRA, HMGN1, HES1, NOTCH1, EDNRB, PRKDC, TACSTD2, SERPINB5, FRS2, UHRF1, SIX1, RAB33B, SIX4, SMAD3 |
| regulation of epithelial cell proliferation involved in lung morphogenesis | biological process | SOX9 |
| regulation of epithelial cell proliferation involved in prostate gland development | biological process | SHH, NOTCH1 |
| regulation of epithelial to mesenchymal transition | biological process | ELL3, PHLDB1, POFUT2, TIAM1, PHLDB2, MCRIP1, TGFBR1, CLASP2, DAG1, EPHA3, CLASP1, GREM1 |
| regulation of epithelial to mesenchymal transition involved in endocardial cushion formation | biological process | TGFB1, TGFB3 |
| regulation of epithelium regeneration | biological process | EPPK1 |
| regulation of ER to Golgi vesicle-mediated transport | biological process | SCFD1, GAS1, RNF139, YIPF5, RINT1, LRRK2 |
| regulation of ER-associated ubiquitin-dependent protein catabolic process | biological process | HERPUD1 |
| regulation of ERBB signaling pathway | biological process | SH3TC2 |
| regulation of ERK1 and ERK2 cascade | biological process | ERBB2, FGFR2, GSTP1, BMP4, FN1, CCN1, FAM83D, RRAS, SYK, RASGRP1, PTPN6, ARHGEF5, ROS1, YWHAZ, NEK10, EPHB1, APIP, TIAM1, TRAF7, LYN, FRS2, CEACAM1, EPHA2, EPHA7, PKHD1 |
| regulation of erythrocyte differentiation | biological process | SPI1, CDK6, LYN |
| regulation of establishment of blood-brain barrier | biological process | ADGRA2, RECK |
| regulation of establishment of cell polarity | biological process | KANK1, SHTN1, ARFGEF1, RACK1, RNF41, ROCK2, GATA3, ROCK1, RUFY3, KIF20B, KRIT1, BCAS3, CDH5, PTK2B, RAP1B, RIPOR2 |
| regulation of establishment of endothelial barrier | biological process | TNF, IL1B, TNFRSF1A, PPP1R12A, ROCK2, ROCK1, VCL, IKBKB |
| regulation of establishment of planar polarity | biological process | VANGL2, SFRP2, SAPCD2 |
| regulation of establishment of planar polarity involved in neural tube closure | biological process | SEC24B |
| regulation of establishment of protein localization | biological process | SNAP25, EPB41L5, NSD2, KIF20B, KIAA0586, CEP290, HDAC6 |
| regulation of establishment of protein localization to chromosome | biological process | SPIDR |
| regulation of establishment of protein localization to plasma membrane | biological process | AR |
| regulation of establishment or maintenance of cell polarity | biological process | TEK, LLGL1, LLGL2 |
| regulation of estradiol secretion | biological process | KDM5B |
| regulation of euchromatin binding | biological process | CTNNB1 |
| regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction | biological process | DMPK |
| regulation of excretion | biological process | SLC9A3R1, NPHS1 |
| regulation of exit from mitosis | biological process | ZW10, CDC23, PPP1R9B, ANLN, SIRT2, CDC14B, CDKN1B, KNTC1 |
| regulation of exocyst assembly | biological process | RALB |
| regulation of exocyst localization | biological process | RALB |
| regulation of exocytosis | biological process | RAB21, RIMS2, RALA, NSF, RAB3C, CPLANE2, CPLX1, RAB8B, SYT1, STXBP5, RAB27B, RAB15, RAB3B, STX1B, RAB26, LGI3, SEPTIN1, SEPTIN5, STX4, RAB8A, RAB3D, RPH3AL, STXBP5L, HAP1, CPLX2, RAPGEF4 |
| regulation of extracellular exosome assembly | biological process | TSG101, STAM, PDCD6IP |
| regulation of extracellular matrix assembly | biological process | NOTCH1, HAS2, AGT |
| regulation of extracellular matrix constituent secretion | biological process | RIC1 |
| regulation of extracellular matrix disassembly | biological process | DDR1, ETS1, LRP1, FGFR4 |
| regulation of extracellular matrix organization | biological process | SLC2A10, ABL1, TCF15 |
| regulation of extrathymic T cell differentiation | biological process | PRDM1, ZNF683 |
| regulation of extrinsic apoptotic signaling pathway | biological process | BCL2L12, PTPRC, ACSL5, BCL2L14, DEPTOR, MADD, TRAF1, DBH |
| regulation of extrinsic apoptotic signaling pathway in absence of ligand | biological process | FGFR1 |
| regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | FAS, TNFSF10, FASLG, CASP8, FEM1B, TNFRSF10B, FADD, CFLAR, SP100, TRADD, MADD, TNFRSF10A, STX4, TMC8, TRAF2 |
| regulation of eye pigmentation | biological process | SPNS2 |
| regulation of Fas signaling pathway | biological process | SP100, ZDHHC7 |
| regulation of fat cell apoptotic process | biological process | SPTLC1 |
| regulation of fat cell differentiation | biological process | LEP, PPARG, LGALS12, GNB3, PPARD, MEX3C, HES1, SIRT2, GPS2, ALOX5, NR1D1, HDAC6, WNT10B, DLK2, RORC, TNF |
| regulation of fatty acid beta-oxidation | biological process | MTOR, MLYCD, LONP2, ABCD1, ABCB11 |
| regulation of fatty acid biosynthetic process | biological process | PDK4, SCAP, ADIPOR1, PRKAG2, ADIPOQ, ADIPOR2, PRKAA2, EIF6 |
| regulation of fatty acid metabolic process | biological process | PANK2, SCAP, PRKAG2, SREBF1, NFE2L1, TREX1, PPARA, CAV1 |
| regulation of fatty acid oxidation | biological process | MLYCD, PDK4, CPT1A, PRKAG2, FABP3 |
| regulation of Fc receptor mediated stimulatory signaling pathway | biological process | PLSCR1, CSK |
| regulation of feeding behavior | biological process | STAT3, LEPR, TACR3, GNB3, QRFP, GHSR, NMU, CNR1, MC3R |
| regulation of female gonad development | biological process | INSR, NUPR1 |
| regulation of ferrochelatase activity | biological process | FXN |
| regulation of fertilization | biological process | TEKT3 |
| regulation of fever generation | biological process | EDNRB |
| regulation of fibrinolysis | biological process | APOH |
| regulation of fibroblast apoptotic process | biological process | XRCC2, IER3IP1, TP53 |
| regulation of fibroblast growth factor receptor signaling pathway | biological process | FGFR2, DUSP6, FAM20C, RUNX2, SULF1, HHIP |
| regulation of fibroblast migration | biological process | MTA2, CORO1C, SDC4, RCC2, PRR5L, GNA12, FER, CLN3, APPL2, APPL1 |
| regulation of fibroblast proliferation | biological process | CTNNB1, ZMPSTE24 |
| regulation of filopodium assembly | biological process | FMR1, CDC42, FXR1, ABITRAM, RAB5A, FXR2, PPP1R16B, MYO10, PPP1R9A, ARF6, DMTN, RAB17, TRPM2, GAP43 |
| regulation of flagellated sperm motility | biological process | ANXA5, TPPP2, TEX101 |
| regulation of focal adhesion assembly | biological process | PEAK1, CORO1C, PTK2, MACF1, ROCK2, TSC1, GPM6B, RHOD, SLC9A1, EFNA5, ROCK1, ACTG1, SLK, VCL, LDB1, LIMCH1, DUSP3, EPHA3, CLASP1, CAMSAP3, GREM1 |
| regulation of follicle-stimulating hormone secretion | biological process | INHBA |
| regulation of forebrain neuron differentiation | biological process | GATA2 |
| regulation of fusion of sperm to egg plasma membrane | biological process | NOX5 |
| regulation of G-protein coupled receptor protein signaling pathway | biological process | ITGB1, DYNLT1, GRK5, TULP3, PDCL, RGS16, GNG7, RGS20, GRK4, RAMP2, RASGRP4, HOMER2, RIC8B, FRMPD1, GIT1, RGS11, USP33, PLCE1, RGS2, RGS10, GNG4, RGS5, KCTD12, GRK6, GIT2, ZDHHC3, RGS6, RGS1, RAMP3, ZDHHC7, KCTD8, RGS14, RAMP1, RGS18, USP20, ARRB2, RGS12, DGKQ, GRK1, RGS9, TUB, RGS4 |
| regulation of G1/S transition of mitotic cell cycle | biological process | E2F1, SENP2, TMEM14B, KIF14, PSME1, PTPN6, ECD, CCND1, BID, APPL2, ID2, APPL1, INO80, TM4SF5, PLK5 |
| regulation of G2/M transition of mitotic cell cycle | biological process | CDKN2A, CCNA2, OFD1, PCM1, CEP57, HAUS2, CETN2, CEP70, CCP110, RNASEH2B, NEDD1, CEP41, HAUS4, CSNK1E, HMMR, DYNC1I2, KIF14, CDK5RAP2, DCTN3, HAUS5, CEP131, CEP43, TPX2, CSNK1D, CENPF, SDCCAG8, TUBB, PLK1, YWHAE, TUBB4B, AKAP9, CEP164, TUBG1, PKIA, ALMS1, CEP63, HAUS6, DCTN2, CNTRL, CEP290, ACTR1A, CKAP5, TUBB4A, MAPRE1, YWHAG, CEP250, SFI1, PCNT, PRKAR2B, NDE1, PPP2R1A, NINL, CLASP1, KCNH5, CEP192, CEP72, SSNA1, NEK2, CCNB3 |
| regulation of GABA-A receptor activity | biological process | SHISA7 |
| regulation of gamma-aminobutyric acid secretion | biological process | SV2A |
| regulation of gamma-delta T cell differentiation | biological process | TCF7, EGR3 |
| regulation of gastric acid secretion | biological process | SGK1, HIP1R |
| regulation of gastric motility | biological process | GHSR, TYMP |
| regulation of gastrulation | biological process | NODAL, PHLDB1, PHLDB2, HNF4A, POGLUT1, CLASP2, DAG1, CRB2, TGIF2, CLASP1 |
| regulation of gene expression | biological process | DDX3Y, TGFB1, APOE, BCL2, IL10, FAS, AHR, HIF1A, CYP1A2, DNMT1, MDM2, EZH2, PEG3, DNMT3B, PLAGL1, GNRH1, APP, FGFR1, CTNNB1, IGF1, BMP4, PIK3CA, SOHLH1, SOX2, SHH, DROSHA, MYC, GDNF, PATZ1, GLI3, RO60, ATP6V1B1, PCBP4, OLIG3, TBK1, MOK, TRIM17, YBX3, PAX7, ISL1, PRDM13, NOVA2, IGF2BP2, MAP3K4, TRIM13, MAPK6, ZC3H12A, POGZ, USP16, IL7, GNB3, PIN1, NPAT, MAPK11, NELL1, PHOX2B, KDM6B, EOMES, MAPK4, ZNF827, PHLDA2, TRIM58, TRIM11, PCBP3, PRDM2, PCBP1, RNF41, PPP3CB, IREB2, FOXA1, SART3, TRIM68, ATRAID, TRIM44, SRPK1, TRIM15, ZNF407, DPPA5, TSPAN8, YBX1, UBXN2A, SRPK2, TSHZ1, ZNF438, ALPK2, EOLA1, KDM4C, FOXN1, COL2A1, NOTCH1, REST, MCPH1, FOXP1, MITF, PRDM1, TBR1, BCL11B, HMG20B, PDX1, TRIM40, ZNF597, ZNF335, RC3H2, TRIM10, POFUT2, PTPRC, NFKBIA, NR4A2, LHX1, PSEN1, ASCL1, AFF2, STX1B, EMX2, STOX1, MEGF8, ZNF683, STK40, SMO, FUT8, UTY, TSHZ2, HNRNPDL, LOX, BMI1, CRIP1, MECP2, CDK6, NIPBL, THOC2, ATXN7L3B, ZNF71, ZNF451, TRIM38, TAPBP, MAPK9, INSM1, C1D, RC3H1, SHC4, FUBP1, NLK, ZNF711, SLC8A1, FOXG1, RBPJ, MAPK7, |
| regulation of gene expression by genetic imprinting | biological process | BRCA1, DNMT3L, IGF2, GSK3B, CTCFL, EED, DIRAS3, MECP2, KDM1B, PRMT7 |
| regulation of gene expression, epigenetic | biological process | GPX1, HDAC4, TDG, MORC1, ZNF335, MECP2, MACROH2A1, IFI16, HDAC6, HDAC5, KLF2 |
| regulation of gene silencing | biological process | H3C1 |
| regulation of gene silencing by miRNA | biological process | FMR1, PUM2, NUP93, POLR2F, PUM1, NUP37, NUP88, NUP85, NUP107, NUP43, POM121, POLR2G, NUP35, NUP58, SEC13, NUP205, NUP50, NUP62, IPO8, NUP155, POLR2B, POLR2D, NUP153, RAE1, SEH1L, POLR2J, POLR2L, POLR2E, NUP133, POLR2K, AGO2, POLR2I, NUP54, TPR, RANBP2, NUP98, TRIM71, TNRC6A, AGO1, POLR2C, POLR2H, AAAS, H3C1, POLR2A, NUP210, NUP188, NUP42, NUP214, H3-3A, NUP160, H4-16, H3C13, LIN28A |
| regulation of genetic imprinting | biological process | PIK3CA, CTR9, ZNF445 |
| regulation of germinal center formation | biological process | BCL6, MEF2C, RC3H1, PKN1 |
| regulation of glial cell differentiation | biological process | NF1 |
| regulation of glial cell proliferation | biological process | CHRM1 |
| regulation of gliogenesis | biological process | EZH2, NF2 |
| regulation of glomerular filtration | biological process | EMP2, PTPRO, CORO2B |
| regulation of glucagon secretion | biological process | PASK, SYT7 |
| regulation of glucocorticoid mediated signaling pathway | biological process | AKAP13 |
| regulation of glucocorticoid metabolic process | biological process | STUB1, GAL |
| regulation of gluconeogenesis | biological process | LEP, SELENOS, OGT, GNMT, FBP1, NLN, USP7, SDHAF3, RANBP2, SIRT7, SESN2, DGKQ, PDK2 |
| regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter | biological process | FOXO1 |
| regulation of glucose import | biological process | PRKAG2, PLA2G1B, HK2, APPL1, RTN2, ASPSCR1 |
| regulation of glucose metabolic process | biological process | NCOA2, MLYCD, PDK4, PDK3, GNB3, ADIPOR1, ZMPSTE24, PRKN, ADIPOQ, RORA, LCMT1, IGFBP4, PDK1, C1QTNF1, FOXK2, NFE2L1, ACACB, FOXK1, RORC, PDK2 |
| regulation of glucose transmembrane transport | biological process | STXBP4, TRIB3, PRKCB, EDN1 |
| regulation of glucosylceramidase activity | biological process | SCARB2, ATP13A2 |
| regulation of glutamate receptor signaling pathway | biological process | PRNP, FRRS1L |
| regulation of glutamate uptake involved in transmission of nerve impulse | biological process | PER2, ATP1A2 |
| regulation of glutamine family amino acid metabolic process | biological process | SIRT4 |
| regulation of glycogen biosynthetic process | biological process | AKT1, MTOR, PPP1R3D, PPP1CB, PPP1R3C, PPP1R3B, INPP5K |
| regulation of glycogen catabolic process | biological process | PPP1R3D, PPP1CB, PPP1R3B |
| regulation of glycogen metabolic process | biological process | PHLDA2, KHK, GCGR, RUBCNL, POMC |
| regulation of glycolytic process | biological process | HIF1A, PGAM1, NUP93, NUP37, NUP88, NUP85, OGT, NUP107, NUP43, POM121, NUP35, NUP58, SEC13, NUP205, NUP50, NUP62, PRKAG2, NUP155, NUP153, RAE1, SEH1L, EP300, NUP133, NUP54, TPR, RANBP2, NUP98, EIF6, AAAS, ZBTB7A, TREX1, SLC2A6, GCK, NUP210, JMJD8, NUP188, NUP42, NUP214, NUP160 |
| regulation of glycoprotein biosynthetic process | biological process | BCL2, GATA1 |
| regulation of Golgi inheritance | biological process | MAPK3, MAPK1, MAP2K2, MAP2K1 |
| regulation of Golgi lumen acidification | biological process | SLC9A7 |
| regulation of Golgi organization | biological process | USP6NL, CAMSAP2, STX5, STX18, MYO5A, AKAP9, PDE4DIP, RAB33B, EHD3, CAMSAP3, ARMH3 |
| regulation of granulocyte chemotaxis | biological process | CAMK1D |
| regulation of granulocyte differentiation | biological process | RARA |
| regulation of granulocyte macrophage colony-stimulating factor biosynthetic process | biological process | IL17F |
| regulation of granulosa cell apoptotic process | biological process | BOK |
| regulation of grooming behavior | biological process | NMU, DLG4, CNTNAP4 |
| regulation of growth | biological process | IFNG, GAS6, MCTS1, MORF4L2, NDN, TSG101, OPA3, CISH, MORF4L1, SOCS2, ACTL6A, PPP2CA, SHC1, ZMAT3, MRGBP, SOCS5, RACK1, DAB2IP, SOCS4, OGFR, YEATS4, DMAP1, RUVBL2, TSPYL5, ING2, SOCS1, UBE2E3, SELENOP, PRAME, TKT, HMGA2, ING3, NEDD9, KAT5, IGFBP4, OSGIN1, RUVBL1, NSMCE3, EPC1, TGFBR1, BRD8, LRP12, SOCS7, CREG1, OSM, E4F1, TMEM8B, SOCS6, IGFBP2, BCL2L1, SAFB, TGFBR2, HOXB13, TLE5, DLL1, CSPG5, IGFBP5, GPC3, CAPRIN2, PPP2R1A, PTCH1, IHH, KCTD11, FAM107A, SOCS3, CCDC85B, GAP43 |
| regulation of growth hormone activity | biological process | PHLDA2 |
| regulation of growth hormone receptor signaling pathway | biological process | HNF4A |
| regulation of growth hormone secretion | biological process | CHD7, GHSR |
| regulation of growth plate cartilage chondrocyte proliferation | biological process | CARM1, POR |
| regulation of growth rate | biological process | BNIPL |
| regulation of GTP binding | biological process | CSNK1A1, ARHGEF7 |
| regulation of GTPase activity | biological process | SOD1, MTOR, DYNLT1, SBF1, RASA1, TBC1D15, EVI5, GPR137B, CHN1, IQGAP1, IQGAP2, ALS2, BCL6, RASGRP3, RALBP1, DAB2IP, BVES, VAV3, PLXNC1, OCRL, PTK2, RASA2, IQGAP3, ARHGAP9, RABGAP1, RAPGEF6, ARHGEF5, AJUBA, RASAL2, STMN3, DGKI, NTRK2, EFNA5, ARHGAP27, SBF2, ITGB1BP1, CHN2, FGD6, PLXNA1, VAV2, PRKG1, TBC1D10B, RAB3GAP2, ARHGAP6, ADAP1, RDX, EPHA4, GAPVD1, PLXNA4, EPHA1, FGD4, NGEF, RAP1GAP, FGD2, EVI5L, MLST8, PYCARD, ARHGAP15, PLXNB3, EPHA3, CRK, RAB3GAP1, ARHGAP12, RASA4, VAV1, PLXNA3, PLXNB2, PLXNB1, PLXNA2, EPHB3, RASA3, PROM2, PLXND1, RASAL3, RASAL1, NF1, ARHGAP44, RASIP1, FGD5, TRAPPC6B |
| regulation of guanylate cyclase activity | biological process | GUCA1C |
| regulation of hair cycle | biological process | CLOCK, PER1, NIPBL, FA2H, ARNTL |
| regulation of hair cycle by canonical Wnt signaling pathway | biological process | CDH3 |
| regulation of hair follicle development | biological process | HPSE, SMAD4, MYSM1 |
| regulation of heart contraction | biological process | GNAO1, THRB, GJA1, TPM1, DMPK, CAMK2D, DES, SRI, CYP2J2, ZMPSTE24, TMIGD3, FXYD1, CAV3, GLP1R, CELF2, PLN, ADORA3, HBEGF, CALCA, KCNG2, TH, CACNA1H, KCNIP2, HRC, MYH6, KCNJ12, THRA, CACNA1B, FOXN4, CHRM2, S100A1, TBX2, HSPB7 |
| regulation of heart growth | biological process | DUSP6, MYH6 |
| regulation of heart morphogenesis | biological process | SMO |
| regulation of heart rate | biological process | MYH7, MDM2, SEMA3A, GJA1, OXT, DMD, BVES, CASQ2, RYR2, RANGRF, CAV3, CALM1, CALM2, CALM3, ANK2, TNNI3K, GPD1L, SLC8A1, CACNA1G, FKBP1B, PDE4D, POPDC2, IRX5, EPAS1, HRC, SNTA1, HCN4, MYH6, DRD2, SCN5A, AGT, SCN10A, MC3R |
| regulation of heart rate by cardiac conduction | biological process | CACNA2D1, CAMK2D, CTNNA3, KCNH2, KCND3, CACNA1C, SCN1B, DSP, YWHAE, ANK2, AKAP9, CACNA1G, KCNE4, PKP2, GJA5, KCNJ2, DSG2, DSC2, JUP, KCNE1, CACNA1D, TRPM4, SCN4B, HCN4, SCN5A, BIN1, SCN2B, CACNB2, SCN3B, KCNE3, CAV1 |
| regulation of heart rate by chemical signal | biological process | NOS1AP, SREBF1 |
| regulation of heart rate by hormone | biological process | KCNH2, YWHAE |
| regulation of hematopoietic progenitor cell differentiation | biological process | PDCD2, EIF2AK2 |
| regulation of hematopoietic stem cell differentiation | biological process | PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, ITCH, PSMB7, PSMD6, PSMD1, PSMD14, LMO1, PSMD7, PSMB6, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, PSMB8, PSMD4, CBFB, PSMC3, PSMA6, RUNX1, GATA3, CDK6, KMT2A, PSMD12, PSMB9, PSMC4, PRKDC, PSMD9, ABL1, PSMA4, PSMD2, GATA2, YAP1, PSMD5, PSMF1, YTHDF2, OSM, LMO2, PSMB3, LDB1, EIF2AK2, PSMD3, PSMC1, SETD1A, PUS7, PSMD13, GATA1, PSMB10 |
| regulation of hematopoietic stem cell proliferation | biological process | ACE, EIF2AK2 |
| regulation of heme biosynthetic process | biological process | TMEM14C |
| regulation of hemoglobin biosynthetic process | biological process | EIF2AK1 |
| regulation of hemopoiesis | biological process | PTN, MYSM1, GFI1B |
| regulation of hepatocyte growth factor receptor signaling pathway | biological process | PTPN2, PTPN1 |
| regulation of hepatocyte proliferation | biological process | IFNG, PLAU, GLI1, SULF2 |
| regulation of high voltage-gated calcium channel activity | biological process | SRI, NOS1AP, CALM3, PDE4B, RRAD |
| regulation of high-density lipoprotein particle assembly | biological process | LCAT |
| regulation of hindgut contraction | biological process | GHSR |
| regulation of hippo signaling | biological process | NF2, MOB3B, NEK8, WWC1 |
| regulation of histone acetylation | biological process | PYGO2, EID1, SETD5, TADA2A, GATA2, MYOCD, FLCN |
| regulation of histone deacetylase activity | biological process | CAMK2D |
| regulation of histone deacetylation | biological process | MAPK8, TADA3, JDP2, ZNHIT1 |
| regulation of histone H2B conserved C-terminal lysine ubiquitination | biological process | WDR70 |
| regulation of histone H3-K14 acetylation | biological process | KMT2A |
| regulation of histone H3-K27 methylation | biological process | GATA3 |
| regulation of histone H3-K36 methylation | biological process | NSD1 |
| regulation of histone H3-K36 trimethylation | biological process | IWS1 |
| regulation of histone H3-K4 methylation | biological process | CTCFL, PYGO2, GATA3, CTR9, ZNF335, GFI1, KMT2B |
| regulation of histone H3-K9 acetylation | biological process | KMT2A, RAPGEF3, HDAC5, CAMK1 |
| regulation of histone H3-K9 methylation | biological process | SETD7 |
| regulation of histone H3-K9 trimethylation | biological process | ATRX, ZNF274 |
| regulation of histone H4 acetylation | biological process | ZMPSTE24, IWS1 |
| regulation of histone H4-K16 acetylation | biological process | ZMPSTE24, SMARCB1 |
| regulation of histone methylation | biological process | MTHFR, PHF1 |
| regulation of histone modification | biological process | UBE2B, CDK9, PARG |
| regulation of histone phosphorylation | biological process | AKAP8, AKAP8L |
| regulation of histone ubiquitination | biological process | UBE2N |
| regulation of homologous chromosome segregation | biological process | HORMAD1 |
| regulation of hormone biosynthetic process | biological process | STC2, FFAR3, TRERF1 |
| regulation of hormone levels | biological process | SIN3A, BCAT2, SLC39A14 |
| regulation of hormone metabolic process | biological process | TCF7L2, GNB3, ZMPSTE24 |
| regulation of hormone secretion | biological process | ANXA1, CCKAR, SCG5 |
| regulation of humoral immune response | biological process | SPNS2 |
| regulation of humoral immune response mediated by circulating immunoglobulin | biological process | PTPRC |
| regulation of hyaluronan biosynthetic process | biological process | SMPD3 |
| regulation of hydrogen peroxide metabolic process | biological process | INSR, NOXO1, NOXA1, PINK1, RAC1, RAC2 |
| regulation of hydrogen peroxide-induced cell death | biological process | STK26 |
| regulation of I-kappaB kinase/NF-kappaB signaling | biological process | TNF, IL1B, HSPB1, OPTN, SPHK2, BTRC, DAB2IP, TRAF3, CAPN3, SQSTM1, ANGPT1, IKBKG, ZFAND6, CPNE1, TRAF6, TRAF4, CARD8, NLRP12, PIDD1, TRAF5, LIME1, TRAF1, WDR83, PDPK1, TRAF2 |
| regulation of immune complex clearance by monocytes and macrophages | biological process | FCGR2B |
| regulation of immune response | biological process | IFNG, IL4, ICAM1, HLA-B, HLA-A, HLA-E, KIR2DL2, KIR2DS2, C3, ITGB1, B2M, ITGA4, HLA-G, FCGR3A, CD8A, HLA-C, FGL1, SPPL2A, VCAM1, BCL6, CD1C, CD81, TREML1, CD226, NCR3, COL3A1, KLRC1, CD34, NPDC1, COLEC12, CD300LG, SIGLEC7, NCR1, COL2A1, FCGR2B, MADCAM1, CLEC2D, PILRB, CD300C, MOG, BTN3A1, SH2D1B, SPPL2B, CLEC2B, SLA2, TREM1, CD3E, DENND1B, TREML4, COL1A2, CD3G, KIR2DL1, KIR3DL2, BTN3A2, TNFSF13B, TYROBP, CD247, MICB, RAET1E, IFITM1, CXADR, CD96, BTNL9, HHLA2, FCGR3B, BTN3A3, ITGB7, CLEC4G, OSCAR, CGAS, CD200R1, SLAMF6, ERMAP, TREM2, CRTAM, ITGB2, IRF1, LAIR1, CD300LF, IRF7, ULBP3, TBX21, DNASE2, FCGR2A, CD33, FCER1G, SFTPD, VTCN1, TNFRSF13C, ICAM5, CD22, ICAM3, TREML2, JAML, LILRA1, CD160, SELL, PVR, LAIR2, ULBP1, CD300LB, SLAMF7, COL17A1, SIGLEC9, ICOSLG, ITGAL, CD19, CD40, CARD11, VSIR, CD8B, SMAD3, CD300E, BTNL3, HLA-F, ICAM4, KLRF1, FCGR2C, BTNL8 |
| regulation of immune system process | biological process | PIP, BCL6, ZBTB6, ORM1, SIAE, ZBTB20, ZBTB37, ZBTB32, BCL6B, ZBTB26, ORM2, GGT1, ZBTB45, ZBTB34, ZNF131 |
| regulation of immunoglobulin production | biological process | CGAS, PKN1, TREX1 |
| regulation of immunoglobulin secretion | biological process | TNF, TRAF6, CD40, TRAF2 |
| regulation of inclusion body assembly | biological process | SNCAIP, BAG5 |
| regulation of inflammatory response | biological process | IL4, CASP1, PTGS2, CASP4, TLR4, SEMA7A, PARK7, BRD4, MAS1, S100A9, ACE2, FANCA, NR1D2, JAK2, LACC1, XIAP, BCL6, IL1R1, ABHD12, MYD88, FANCD2, ANXA1, PIK3AP1, SETD6, SBNO2, PSMA6, MCPH1, FOXP1, NOD2, TBC1D23, IL20, RELA, AGTR1, ZBP1, LRRC19, SHPK, BIRC2, NLRP3, CYLD, BCL6B, LYN, ALOX5, NLRP1, S100A8, TNFSF4, TNIP1, DUOXA2, STING1, PGLYRP2, GRN, BST1, NFE2L1, DAGLB, PYCARD, HCK, DUOXA1, AKNA, GGT1, IRF3, IL1RL2, TREX1, BAP1, MGLL, ADAMTS12, USP18, AHSG, SLC7A2, TNF, ESR1, AGER, ZYX |
| regulation of inflammatory response to wounding | biological process | ALOX5 |
| regulation of inhibitory synapse assembly | biological process | LHFPL4 |
| regulation of innate immune response | biological process | ERAP1, XIAP, TKFC, DHX58, FCGR2B, RNF135, TIRAP, PTPN22, BIRC2, TREML4, SAMHD1, APPL2, TREM2, FGR, IRF1, TREML2, APPL1, TREX1, DUSP10 |
| regulation of inner ear auditory receptor cell fate specification | biological process | ESRP1 |
| regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | biological process | MYO5A, ASPH |
| regulation of inositol trisphosphate biosynthetic process | biological process | PTK2B |
| regulation of insulin receptor signaling pathway | biological process | BAIAP2L1, OGT, SESN3, PIK3R1, PTPN1, FFAR3, VWA2, SIK2, FUT7, TSC2, CCND3, MZB1 |
| regulation of insulin secretion | biological process | TNF, IFNG, IL1B, GNAS, LEP, CCL5, NOS2, RAP1A, CLOCK, SLC25A4, RFX3, CACNA1E, ARL2BP, ARL2, CPT1A, PPP3CB, SLC25A6, CACNA1C, SLC25A5, CELA2A, PER2, GIPR, ITPR3, CACNA2D2, CACNA1A, ADRA2A, SNAP25, NEUROD1, CNR1, GLP1R, KCNB1, DPP4, ALOX5, ICA1, ITPR1, UQCC2, SREBF1, HNF4A, ITPR2, CARTPT, RFX6, KCNS3, KCNG2, ARNTL, RAPGEF3, SLC16A1, CACNA1D, TCIRG1, SYT9, KCNC2, ADRA2C, EIPR1, GCK, SYT7, SSTR5, ABCC8, SLC8B1, G6PC2, RAPGEF4 |
| regulation of insulin secretion involved in cellular response to glucose stimulus | biological process | BRSK2, STXBP4, HMGN3, EFNA5, TIAM1, SLC9B2, NR1H4, SIDT2, NR1D1, PRKCE, LRP5, ADCY5, LRP5L, FOXA2 |
| regulation of insulin-like growth factor receptor signaling pathway | biological process | IGFBP1, ZFAND2B, GHRHR, IGFBP4, IGFBP2, IGFBP5, IGFBP6 |
| regulation of integrin activation | biological process | SELP, FBLIM1, FARP2 |
| regulation of integrin biosynthetic process | biological process | S100A9 |
| regulation of integrin-mediated signaling pathway | biological process | TIMP1, PRKD1, ITGB1BP1, BST1 |
| regulation of interferon-beta production | biological process | TRAF3, TIRAP, TRIM38, RNF216 |
| regulation of interferon-gamma production | biological process | CD47, ISG15, ZNF683, RIPK3, CCR7 |
| regulation of interferon-gamma-mediated signaling pathway | biological process | IFNG, STAT1, SUMO1, JAK2, PIAS1, IFNGR1, PTPN2, IFNGR2, SOCS1, JAK1, SOCS3, CDC37 |
| regulation of interleukin-1 beta production | biological process | F2R, S1PR3 |
| regulation of interleukin-1 beta secretion | biological process | FOXP1, CCR7 |
| regulation of interleukin-1 production | biological process | ANXA1 |
| regulation of interleukin-1-mediated signaling pathway | biological process | VRK2, ZBP1 |
| regulation of interleukin-10 production | biological process | CD47 |
| regulation of interleukin-10 secretion | biological process | HLA-DRB1 |
| regulation of interleukin-12 biosynthetic process | biological process | MAST2 |
| regulation of interleukin-12 production | biological process | HLA-B, CD47 |
| regulation of interleukin-12 secretion | biological process | FOXP1 |
| regulation of interleukin-18 biosynthetic process | biological process | NLRP12 |
| regulation of interleukin-2 biosynthetic process | biological process | CARD9, IL17F |
| regulation of interleukin-23 production | biological process | TGFB1 |
| regulation of interleukin-4 production | biological process | HLA-DRB1, LGALS9 |
| regulation of interleukin-6 biosynthetic process | biological process | CARD9, IL17F |
| regulation of interleukin-6 production | biological process | HLA-B, CAPN2, CD47, EOLA1, AFAP1L2, TREM2 |
| regulation of interleukin-8 biosynthetic process | biological process | IL17F |
| regulation of interleukin-8 production | biological process | PTPRC |
| regulation of interleukin-8 secretion | biological process | CRP, C5AR2, SSC5D |
| regulation of intestinal absorption | biological process | EPB41 |
| regulation of intestinal cholesterol absorption | biological process | LEP, APOA1, APOA5 |
| regulation of intestinal epithelial structure maintenance | biological process | NEUROD1 |
| regulation of intestinal lipid absorption | biological process | ENPP7 |
| regulation of intracellular calcium activated chloride channel activity | biological process | PRNP, GRM5 |
| regulation of intracellular cholesterol transport | biological process | ARV1, NUS1, ABCA2 |
| regulation of intracellular estrogen receptor signaling pathway | biological process | SRC, UFSP2, CARM1, CBFB, RUNX1, DNAAF4, AXIN1, UBA5, LATS1, UFM1, GPAM, DDRGK1, ESR1 |
| regulation of intracellular pH | biological process | SLC26A8, CA2, ATP5F1B, SLC4A7, SLC9C1, SLC9A2, SLC9A1, SLC9A7, SLC4A4, SLC9A9, TM9SF4, SLC9C2, CHP1, SLC4A2, CLN3, SLC4A11, SLC9A6, CA7, SLC4A8, SLC4A1, SLC4A3, SLC26A6, SLC4A10, SLC4A9 |
| regulation of intracellular protein transport | biological process | SNX3, ATP13A2, SNX12, PTPN1, SH3TC2, LCP1, SEPTIN8 |
| regulation of intracellular signal transduction | biological process | LEMD2, CASTOR3, LEMD3, TREM2, ANKRD54, CRK |
| regulation of intracellular steroid hormone receptor signaling pathway | biological process | GHRHR |
| regulation of intracellular transport | biological process | REEP1, WWC1, REEP6 |
| regulation of intraciliary retrograde transport | biological process | TTC21B, TCTEX1D2 |
| regulation of intrinsic apoptotic signaling pathway | biological process | CYLD, PTPMT1, PYCARD, DAPK2 |
| regulation of intrinsic apoptotic signaling pathway by p53 class mediator | biological process | ANKRD2, TP53 |
| regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | HNRNPK |
| regulation of ion transmembrane transport | biological process | CATSPER1, CATSPER2, CACNA2D1, KCNK17, KCNK4, CLCN2, CATSPER4, CATSPER3, CACNA1S, KCNJ10, KCNAB1, KCNH6, SCN11A, NOX1, ASIC2, KCNJ16, CYBB, CLCN1, CACNA1E, KCNH3, KCNH4, CACNG2, KCNA4, CLCNKA, KCNH2, ANO6, KCND3, CACNG6, CACNA1C, HVCN1, KCND2, CLIC4, CACNG3, STOM, CACNG7, KCNIP4, TMEM37, PKD2, KCND1, KCNQ3, NEDD4, SCN1B, CACNA2D2, KCNG1, CACNA1A, KCNQ2, CLIC3, KCNK10, KCNG4, CLCNKB, KCNC4, KCNB1, SCN2A, KCNJ15, GPR89A, GPR89B, NEDD4L, WWP2, CACNA1G, KCNE4, CLIC5, SCN1A, CACNA1I, CLIC1, KCNJ4, KCNV1, TPCN2, KCNF1, CACNG4, HCN2, CACNB4, KCNA6, KCNJ2, KCNV2, KCNS3, KCNIP1, KCNG2, HCN1, CALHM1, CLIC6, KCNK15, KCNAB3, CACNA1H, KCNE1, KCNA2, KCNJ9, KCNIP2, KCNC1, KCNQ4, CACNA1D, CACNB1, CACNG1, KCNJ8, KCNC2, SCN4A, CACNB3, KCNAB2, SCN4B, KCNK7, HCN4, KCNA3, KCNA1, KCNJ12, TRPM5, KCNIP3, CACNA1B, SCN5A, CACNA2D4, KCNH8, TMEM109, KCNJ1, KCNMA1, KCNC3, NALCN, CACNA2D3, KCNH5, KCNG3, TPCN1, SCN10A, SCN2B, CACNB2, CACNG8, KCNK13, KCNQ5, SCN3B, SCN8A, KCNK6, KCNE3, KCNH7 |
| regulation of ion transmembrane transporter activity | biological process | AHCYL1, CHRM3 |
| regulation of ion transport | biological process | FXYD1, FXYD4, FXYD3, CLDN10, FXYD2, FXYD6, FXYD7 |
| regulation of IRE1-mediated unfolded protein response | biological process | HSPA5, COPS5, FICD |
| regulation of isoprenoid metabolic process | biological process | NPC2 |
| regulation of isotype switching | biological process | IL4, IL10, APLF |
| regulation of isotype switching to IgG isotypes | biological process | NDFIP1, IL27RA |
| regulation of JNK cascade | biological process | IGF1R, COPS5, MAPK8IP1, SH3RF1, MAP4K4, EPHB1, SH3RF3, RAPGEF1, ULK4, SH3RF2, RAP2A, MAGI3, PHLPP1, MAPK8IP2, TRAF2, GRIK2 |
| regulation of JUN kinase activity | biological process | PPEF2, DTNBP1 |
| regulation of kainate selective glutamate receptor activity | biological process | KLHL24, NETO2, NETO1 |
| regulation of keratinocyte apoptotic process | biological process | ZFP36, ZFP36L1 |
| regulation of keratinocyte differentiation | biological process | CTSK, ERRFI1, CTSV, CTSL, KRT84, ROCK2, CBFB, RUNX1, ROCK1, AQP3, ZFP36, ZFP36L1, GRHL1, CD109, SGPP1 |
| regulation of keratinocyte proliferation | biological process | SRSF6, OVOL2, PRKD1, BCL11B, EPB41L4B, ZFP36, YAP1, ZFP36L1 |
| regulation of ketone biosynthetic process | biological process | SIRT5 |
| regulation of kidney size | biological process | ASXL1, LRRK2 |
| regulation of killing of cells of other organism | biological process | P2RX7 |
| regulation of kinase activity | biological process | SLAMF8, MCPH1, EMP2, LDB1, AKAP11, LDB2 |
| regulation of kinetochore assembly | biological process | TRAPPC12, SENP6 |
| regulation of lactation | biological process | OAS2 |
| regulation of lamellipodium assembly | biological process | RAC1, FER, CAPZB, EPHA2, TWF2, WAS, DMTN, BIN3 |
| regulation of lamellipodium morphogenesis | biological process | PDPN, VIL1 |
| regulation of lateral mesodermal cell fate specification | biological process | FGFR1, BMPR1A |
| regulation of lateral pseudopodium assembly | biological process | KLHL41 |
| regulation of lens fiber cell differentiation | biological process | CDKN1B |
| regulation of leukocyte adhesion to vascular endothelial cell | biological process | FUT7 |
| regulation of leukocyte cell-cell adhesion | biological process | FUT9, FUT7 |
| regulation of leukocyte chemotaxis | biological process | PTK2B |
| regulation of leukocyte mediated cytotoxicity | biological process | ICAM1 |
| regulation of leukocyte migration | biological process | ANXA1, SMPD3, CXCR3, CRK, CRKL |
| regulation of leukocyte proliferation | biological process | HHEX |
| regulation of leukocyte tethering or rolling | biological process | FUT9, FUT7 |
| regulation of lipid biosynthetic process | biological process | MID1IP1, TREX1, FAM3A |
| regulation of lipid catabolic process | biological process | LGALS12, RARRES2, THRA |
| regulation of lipid kinase activity | biological process | RB1, RBL1, RBL2, NRBF2 |
| regulation of lipid metabolic process | biological process | PPARG, SERPINA3, ACADM, LACTB, NR1D2, G0S2, GLIPR1, OPA3, CYP4A11, TXNRD1, ANGPTL8, CARM1, TRIB3, PLIN2, FDFT1, NCOA6, ADIPOR1, SIN3B, ZMPSTE24, PPARD, CPT1A, ACSL1, ME1, LSR, CREBBP, HELZ2, PLPP1, SMARCD3, GOLM1, DNAJC15, EDF1, HMGCR, PSAP, SLC27A1, BBS4, BCL11B, IRS2, HMGCS2, HMGCS1, FHL2, RGL1, CHD9, APOA1, CNR1, GPS2, CPT2, NCOA1, TGS1, NCOR2, MACROH2A1, RUBCNL, ABCB4, PPP4R3B, ZFP69, GRHL1, HDAC3, TBL1X, PEX11A, NCOR1, NR1D1, PRKCE, APOA5, ANGPTL4, DRD3, HNF4A, ID2, NFE2L1, TNFRSF21, FADS1, FGFR4, ACER1, ALAS1, PPARA, UGT1A9, AGT, ACOX1, TNFAIP8L3, TIAM2, ADGRF5, ANKRD1, C1QTNF2, CD36 |
| regulation of lipid storage | biological process | MEST, FBXW7, ALKBH7 |
| regulation of lipid transport | biological process | PRKN, DISP3 |
| regulation of lipopolysaccharide-mediated signaling pathway | biological process | CD55, TRIM5, CD36 |
| regulation of lipoprotein lipase activity | biological process | ANGPTL8, LPL, GPIHBP1, LIPC, ANGPTL3, PCSK6, FURIN, LMF1 |
| regulation of lipoprotein lipid oxidation | biological process | LEP |
| regulation of lipoprotein metabolic process | biological process | ANGPTL8, LIPG, DGAT2 |
| regulation of liquid surface tension | biological process | BPIFA1 |
| regulation of locomotion | biological process | DRD3, CHRM4, CHRM1, FBXO7, LRRK2 |
| regulation of locomotor rhythm | biological process | ZFHX3, OPRL1 |
| regulation of long-chain fatty acid import into cell | biological process | EPRS1 |
| regulation of long-term neuronal synaptic plasticity | biological process | KCNJ10, CAMK2B, RAB11A, SYNGR1, GRIN1, KRAS, RAB5A, SYNPO, SYP, DLG4, HRAS, RAB8A, DRD2, AGT, NF1, GRM5, GRIK2, NETO1 |
| regulation of long-term synaptic depression | biological process | DGKI, SORCS3 |
| regulation of long-term synaptic potentiation | biological process | YTHDF1, CALB1, NSG1, CYP46A1, NF1, AGER |
| regulation of low-density lipoprotein particle clearance | biological process | NR1H4, CNPY2, FGF21, HNRNPK |
| regulation of low-density lipoprotein particle receptor biosynthetic process | biological process | FURIN, SEC24A |
| regulation of low-density lipoprotein particle receptor catabolic process | biological process | MYLIP, PCSK9 |
| regulation of lung blood pressure | biological process | BMPR2, NAMPT, GCH1 |
| regulation of lymphocyte activation | biological process | LCK, LAX1 |
| regulation of lymphocyte apoptotic process | biological process | CD3G |
| regulation of lymphocyte chemotaxis | biological process | SLC8B1 |
| regulation of lymphocyte differentiation | biological process | FAS, RNF41, NDFIP1 |
| regulation of lymphocyte migration | biological process | GCSAM, STK10, GCSAML, MSN |
| regulation of lysosomal lumen pH | biological process | TMEM165, VPS33A, TMEM175, LRRK2, CXorf21 |
| regulation of lysosomal membrane permeability | biological process | LAPTM4B |
| regulation of lysosomal protein catabolic process | biological process | ATP13A2, MFSD8 |
| regulation of lysosome organization | biological process | LAPTM4B, SCARB2, TREX1 |
| regulation of macroautophagy | biological process | CASP3, ATP6V0A2, GAPDH, MAPK8, GBA, ATP6V1B1, SLC38A9, LAMTOR3, ATP6V1D, ATP6V1G1, VPS26A, ATP6V1B2, RB1CC1, SNX6, SH3GLB1, PRKAB1, LAMTOR5, PRKAG2, ATP6V1E1, VPS26B, RRAGA, SNX32, ATP13A2, ATP6V0E1, ATP6V1G2, CAPNS1, ATP6V1A, RRAGB, SNX5, NEDD4, ULK1, CDK5R1, RHEB, ERN1, ATP6V0E2, ATP6V1C1, EXOC8, EXOC4, EXOC1, ATP6V1H, PRKAA2, RRAGD, CAPN1, ATP6V0D1, LAMTOR1, ATP6V0B, HDAC6, MLST8, CDK5, ATG101, EXOC7, ATP6V1E2, ATP6V0C, RPTOR, ATP6V1C2, ATG13, VPS35, UCHL1, ATP6V0A1 |
| regulation of macrophage activation | biological process | MIF, MUC5B, PJA2, GPR137B, PLA2G10, CD74, RORA, MYO18A, SHPK, MFHAS1, SLC7A2 |
| regulation of macrophage apoptotic process | biological process | TCP1 |
| regulation of macrophage chemotaxis | biological process | MTUS1, MST1, MST1L, PTK2B |
| regulation of macrophage colony-stimulating factor production | biological process | FOXP1 |
| regulation of macrophage derived foam cell differentiation | biological process | CSF1 |
| regulation of macrophage inflammatory protein 1 alpha production | biological process | TREM2 |
| regulation of macrophage migration | biological process | CD81 |
| regulation of macrophage migration inhibitory factor signaling pathway | biological process | ANGPT1 |
| regulation of mammary gland epithelial cell proliferation | biological process | BAX, GPX1, PYGO2, HOXA5, DEAF1 |
| regulation of MAP kinase activity | biological process | TSG101, TRIB3, DUSP19, PPEF2, HGS, TRIB1, KSR1, SNF8, TRIB2, LIME1, CDK12 |
| regulation of MAPK cascade | biological process | INHBA, TGFB3, GDF15, GDF9, BMP15, INHA, ROR1, ATP6AP2, RNF41, SPRED1, PSAP, NTRK2, VRK2, STK40, NPFFR2, GRB2, ULK4, LBH, HRH4, WDR54, PHLPP1, DRD2, ROR2, PRDM11, NF1, MYOC, GRM1 |
| regulation of MAPK export from nucleus | biological process | DNAJC27 |
| regulation of mast cell activation | biological process | PLSCR1, LYN |
| regulation of mast cell chemotaxis | biological process | RAC2 |
| regulation of mast cell degranulation | biological process | RAC2, FER, LYN, UNC13D, C12orf4, PDPK1, FES, ADGRE2, STXBP2 |
| regulation of matrix metallopeptidase secretion | biological process | SLC12A2 |
| regulation of megakaryocyte differentiation | biological process | DPY30, ASH2L, CNOT4, RBM15, AGO4, ITGA2B, RBBP5, WDR5, CBFB, AGO3, L3MBTL1, RUNX1, KMT2D, THBS1, PRKCQ, MEF2C, PF4, LOX, KMT2A, EP300, KMT2C, TNRC6B, KMT2E, TNRC6A, TNRC6C, EIF6, PRMT1, MOV10, NFE2, AGO1, NR4A3, GP1BA, H3C1, KAT2B, SETD1A, KMT2B, ZFPM1, H3-3A, GATA1, H4-16, H3C13 |
| regulation of meiosis I | biological process | PSMA8 |
| regulation of meiotic cell cycle | biological process | SPATA22, ASPM |
| regulation of meiotic cell cycle process involved in oocyte maturation | biological process | YTHDF2, PPP2R1A |
| regulation of meiotic nuclear division | biological process | CDC20, FZR1, PDE3A, MOS, CALR |
| regulation of melanocyte differentiation | biological process | GNA11 |
| regulation of melanosome organization | biological process | ZEB2, GPR143 |
| regulation of melanosome transport | biological process | GPR143 |
| regulation of membrane depolarization | biological process | B2M, FGF12, CAMK2D, FHL1, RANGRF, NEDD4L, NPFF, HCN4, NTSR1 |
| regulation of membrane depolarization during action potential | biological process | PTPN3 |
| regulation of membrane depolarization during cardiac muscle cell action potential | biological process | RANGRF, CAV3, SLMAP, GJA5 |
| regulation of membrane hyperpolarization | biological process | TRPC5, CACNB3 |
| regulation of membrane lipid distribution | biological process | PRELID1, TRIAP1, GBA2, TLCD1 |
| regulation of membrane permeability | biological process | MTOR, TMIGD1, F11R, PDCD6IP |
| regulation of membrane potential | biological process | SLC26A8, GABRB1, KIF5B, KCNJ10, CHRNA5, ASIC1, KCNH6, RIMS2, ASIC2, KCNK2, GABRA2, CHRNE, GRIN1, HTR3B, HTR3A, RIMS1, BVES, KCNH3, KCNH4, CACNG2, KCNH2, POPDC3, TAFA4, RANGRF, CHRNA2, CNIH3, SLC4A4, GABRG2, GABRB3, GLRA3, CHRNB1, GABRA5, ACTN2, NEDD4, CAV3, SLC26A5, ATP1A4, CHRNA7, CHRND, CHRFAM7A, SLC39A8, CHRNA10, GABRB2, GABRA4, ABCB5, PXK, GABRG1, CHRNA3, DLG1, GRIN2C, NEDD4L, PIEZO2, WWP2, GRIK3, GRIK5, CACNA1G, SLC1A6, POPDC2, GABRP, SCN1A, GABRD, HCN2, HTR3E, GLRA1, CHRNA6, HCN1, CACNA1H, GABRR2, SLC4A8, CNIH2, NTSR2, CHRNG, GABRA1, GRIN2A, TRPM4, RIMS3, CHRNB2, GABRA3, CHRNA4, ZACN, GABRQ, HCN4, KCNA1, PIEZO1, KCNH8, GABRR3, KCNMA1, GRIK2, KCNH5, GABRG3, CHRNA1, GLRA2, CHRNB4, LRRK2, RIMS4, KCNH7 |
| regulation of membrane repolarization | biological process | KCNH2, CASQ2, YWHAE, AKAP9, NEDD4L, KCNJ2, AKAP6 |
| regulation of membrane repolarization during action potential | biological process | CACNA2D1, CACNB3, CAV1 |
| regulation of memory T cell differentiation | biological process | BCL6 |
| regulation of mesenchymal cell proliferation | biological process | ZEB1 |
| regulation of mesenchymal cell proliferation involved in prostate gland development | biological process | SHH |
| regulation of mesenchymal stem cell differentiation | biological process | PDGFRA |
| regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis | biological process | WNT9B |
| regulation of mesoderm development | biological process | PUS7 |
| regulation of metabolic process | biological process | LEP, MC2R, GPR119, S1PR1, NTRK2, CNR1, S1PR2, NPBWR1, LPAR1, S1PR5, LPAR3, S1PR3, S1PR4, LPAR2, GPR12, MC1R, MC3R |
| regulation of metallopeptidase activity | biological process | SVBP |
| regulation of metanephric nephron tubule epithelial cell differentiation | biological process | LIF, PAX8, YAP1, WWTR1 |
| regulation of metaphase plate congression | biological process | TTL, MAD1L1, NUMA1 |
| regulation of microglial cell activation | biological process | MMP8 |
| regulation of microglial cell migration | biological process | P2RY12, CX3CR1 |
| regulation of microtubule binding | biological process | PPP2CA, MARK2, GAS8 |
| regulation of microtubule cytoskeleton organization | biological process | CEP70, TRAF3IP1, MARK2, RASSF7, CDK2AP2, BICD1, MAP6D1, WNT3A, PHLDB1, EFNA5, ROCK1, CDK5R1, PHLDB2, CYLD, KIF18A, BICD2, TAOK1, MAP6, PRKAA2, EPHA3, TPPP, FAM107A, CLASP1, CAMSAP3, DIXDC1 |
| regulation of microtubule depolymerization | biological process | MAP1S, MAP1B |
| regulation of microtubule motor activity | biological process | CFAP73, CFAP100, NDE1 |
| regulation of microtubule nucleation | biological process | EML2 |
| regulation of microtubule nucleation by Ran protein signal transduction | biological process | RANGRF |
| regulation of microtubule polymerization | biological process | CAMSAP1, CAMSAP2, MAPRE3, ARL2, SLC39A12, MAP2, ABL1, GBA2, SLAIN2, CLASP2, PRUNE1, CAMSAP3 |
| regulation of microtubule polymerization or depolymerization | biological process | STMND1, MAPRE3, STMN1, STMN3, GAS2L1, SKA2, MAPRE1, CLASP2, GAS2L2, SKA1, CLASP1 |
| regulation of microtubule-based movement | biological process | IGBP1, HDAC6 |
| regulation of microtubule-based process | biological process | ERBB2, GSK3B, MACF1, CEP120, DIAPH1, APC, CLASP2, MEMO1 |
| regulation of microvillus assembly | biological process | PLD1, KLF5, PODXL, ATP8B1, FSCN1 |
| regulation of microvillus length | biological process | EZR, PLS1, USH1C, TWF2, CDHR5, CDHR2, VIL1 |
| regulation of midbrain dopaminergic neuron differentiation | biological process | SFRP2 |
| regulation of miRNA metabolic process | biological process | DROSHA, RC3H2, RC3H1, KHSRP |
| regulation of mismatch repair | biological process | AXIN2 |
| regulation of mitochondrial ATP synthesis coupled proton transport | biological process | DNAJC30, ATPSCKMT |
| regulation of mitochondrial depolarization | biological process | GCLC, ABCD1, LRRK2 |
| regulation of mitochondrial DNA metabolic process | biological process | STOX1, MPV17 |
| regulation of mitochondrial fission | biological process | TMEM135, INF2, MARCHF5, STAT2, DHODH, LRRK2 |
| regulation of mitochondrial fusion | biological process | PID1 |
| regulation of mitochondrial membrane permeability | biological process | TP53, BCL2, BAK1, STAT3, BAD, CNP, PPIF, BNIP3, BCL2L1, SPG7 |
| regulation of mitochondrial membrane permeability involved in apoptotic process | biological process | BAX, NAIF1, BID, THEM4, CAMK2A, TP53 |
| regulation of mitochondrial membrane permeability involved in programmed necrotic cell death | biological process | BAX, ALKBH7, PPIF |
| regulation of mitochondrial membrane potential | biological process | SOD1, BCL2, BAX, BAK1, PANK2, PARK7, RTL10, PRELID1, CCN6, SLC25A33, PPA2, PRKN, SLC25A36, NDUFS1, BCO2, PID1, STOX1, PINK1, PRDX3, SPART, OPRD1, CLIC1, TUSC2, PYCR1, BCL2L1, MUL1, UBB, ADORA2A |
| regulation of mitochondrial mRNA stability | biological process | FASTKD1, FASTKD5, FASTKD2, FASTK, FASTKD3, TBRG4 |
| regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | TMEM102, MUL1 |
| regulation of mitochondrial translation | biological process | TACO1, NSUN3, SHMT2, LRPPRC, TSFM, ALKBH1, MTG1 |
| regulation of mitochondrion organization | biological process | DNM1L, PARL, MFF, PRKN, ATP13A2, SQSTM1, STOX1, PINK1, EP300, BNIP3, MIEF2, GOLPH3, FIS1, RHOT2, RHOT1, SIRT7, MUL1, PDE2A, VPS35 |
| regulation of mitophagy | biological process | CSNK2A2, DNM1L, VDAC1, PARL, SREBF2, FBXW7, HAX1, HTRA2, BNIP3L, CTTN, ATP13A2, PINK1, USP36, HDAC6, SREBF1, FZD5 |
| regulation of mitotic cell cycle | biological process | RB1, CDK9, RBL1, HNRNPU, RBL2, RNF20, STK3, MAP3K4, IQGAP1, MAP4K2, NEK1, STK4, MAP4K1, THAP1, ZMPSTE24, STK25, DYNLT3, CKS1B, CDK5RAP3, STRADB, MAP3K8, ZNF268, MAEA, TAOK2, STK10, MAP4K3, AFAP1L2, MAP4K4, MAP2K4, MAP2K3, TAOK3, MAP2K7, ASCL1, PAK6, PLK1, MAP3K3, SRA1, MAP2K2, CYLD, SDCBP, STRADA, TNIK, FOXG1, MAP3K19, SLK, STK26, RNF40, RPA3, NEK4, TAOK1, TTC28, AATF, MAP3K2, CDKN1A, MAP2K6, TTLL12, TMEM8B, MAP2K1, CDC26, MAP3K14, PAK3, OXSR1, PAK4, MAP2K5, GBF1, CDKN1C, PIM2, CKS2, NEK6, PAK5, SIK1, PTCH1, PIM3, CDK11B, MINK1, CDK11A, MAP3K1, NEK7, ASAH2 |
| regulation of mitotic cell cycle DNA replication | biological process | ZMPSTE24 |
| regulation of mitotic cell cycle phase transition | biological process | ERCC2, XPC, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, BUB3, SKP1, CDC16, PSMD6, PSMD1, CDC23, PSMD14, PSMD7, ANAPC15, FZR1, BTRC, PSMB6, ANAPC16, BUB1B, PSMD10, PSMD8, PSMC5, ANAPC5, PSMB4, PSME1, CUL1, NEK11, UBD, PSMB8, PSMD4, ATAD5, PSMC3, PSMA6, ANAPC7, PLK1, MAD2L1, ANAPC11, PSMD12, PSMB9, PSMC4, MAD1L1, PSMD9, PSMA4, PSMD2, CDC27, UBE2D1, UBE2E1, PSMD5, PSMF1, PSMB3, CDC26, PSMD3, PSMC1, ANAPC1, UBE2C, ANAPC4, ANAPC2, TFAP4, DDB1, PSMD13, PSMB10 |
| regulation of mitotic cell cycle spindle assembly checkpoint | biological process | CCNB1, ANAPC15, CDK5RAP2, USP44, LCMT1, DUSP1 |
| regulation of mitotic cell cycle, embryonic | biological process | E4F1 |
| regulation of mitotic centrosome separation | biological process | CEP85, MAP9, NEK2, KIF11 |
| regulation of mitotic cytokinesis | biological process | ANKRD53, MAP9, DCDC1, INCENP |
| regulation of mitotic metaphase/anaphase transition | biological process | CENPE, HECW2, CDC23, CDC6, PLK1, CDC26, UBE2C, RIOK2, NEK6, ANAPC4 |
| regulation of mitotic nuclear division | biological process | CDC25C, CDC42, FBXO43, BORA, CUL9, PIN1, L3MBTL1, MKI67, CAV2, CDK13, KIF20B, OBSL1, RCC1, CUL7, NFE2L1, PKMYT1, FBXW5, CCDC8, PDXP, NEK2 |
| regulation of mitotic recombination | biological process | MRE11, RAD50 |
| regulation of mitotic sister chromatid separation | biological process | TPR |
| regulation of mitotic spindle assembly | biological process | HNRNPU, CHMP2A, DRG1, CHMP5, VPS4B, CHMP4B, CHMP1A, PLK1, CEP97, TPR, PDCD6IP, RCC1, CHMP4C, CCSAP, CHMP3, RIPOR2, HSPA1A, HSPA1B, CHMP1B |
| regulation of mitotic spindle organization | biological process | PKD1, BORA, GPSM2, NUP62, TPX2, RAE1, PARP3, ANKRD53, TACC3, MAP9, NUMA1, CLTC, PSRC1, FSD1 |
| regulation of modification of postsynaptic actin cytoskeleton | biological process | BAIAP2, CTTNBP2, TIAM1, CYFIP1, ITSN1 |
| regulation of modification of postsynaptic structure | biological process | CAMKV |
| regulation of modification of synaptic structure | biological process | GRIPAP1, ABL1, EPHA4, CLN3 |
| regulation of molecular function, epigenetic | biological process | ASIP |
| regulation of monocyte chemotaxis | biological process | LYN |
| regulation of monocyte differentiation | biological process | FOXP1, IRF7 |
| regulation of morphogenesis of a branching structure | biological process | FGFR2, PGF, BMP4, GDNF |
| regulation of motor neuron apoptotic process | biological process | KCNB1 |
| regulation of mRNA 3'-end processing | biological process | PAPOLA, AHCYL1, ZFP36L1 |
| regulation of mRNA binding | biological process | CARM1, EIF4A3 |
| regulation of mRNA export from nucleus | biological process | NSUN2, IWS1, THOC2, TPR, AKAP8L |
| regulation of mRNA processing | biological process | SLTM, NCBP1, SRPK1, SRPK2, IWS1, SAFB, SRPK3, CDK11B, SAFB2, CDK11A |
| regulation of mRNA splicing, via spliceosome | biological process | YTHDC1, C9orf78, TIA1, SRPK1, SRPK2, SRSF3, RBM39, SON, KHDRBS3, RBM23, HNRNPK, RBM42, METTL16 |
| regulation of mRNA stability | biological process | FMR1, AKT1, HSPB1, PABPC1, PUM2, HSPA1A, APEX1, PSMA3, HSPA8, PSMB1, PSMB5, PSMC2, PCBP4, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PUM1, ZC3H14, PSMB7, IGF2BP2, FXR1, PSMD6, PSMD1, DHX36, PSMD14, PARN, ANP32A, PSMD7, EXOSC9, HNRNPD, XPO1, PSMB6, RPS27A, PSMD10, PSMD8, PSMC5, DCP2, SERBP1, PSMB4, PSME1, PSMB8, PSMD4, PCID2, PSMC3, PSMA6, CACNG7, EXOSC7, EXOSC5, YWHAZ, RNASEL, SAMD4A, EXOSC1, FXR2, TNPO1, EXOSC3, PSMD12, PSMB9, PSMC4, ZFP36L2, RC3H1, XRN1, EXOSC8, DIS3, PSMD9, PSMA4, PSMD2, CARHSP1, UBC, PRKCD, EXOSC4, ZFP36, YWHAB, UBA52, ZFP36L1, PSMD5, PSMF1, YTHDF2, PSMB3, RBM24, DCP1A, CSDC2, PSMD3, PSMC1, IGF2BP3, SET, EXOSC6, UBB, PABPC4, EXOSC2, SAMD4B, KHSRP, IGF2BP1, ALKBH5, TNFSF13, NUP214, PSMD13, PSMB10 |
| regulation of mRNA stability involved in cellular response to UV | biological process | NPM1 |
| regulation of mRNA stability involved in response to oxidative stress | biological process | HNRNPM, MYEF2 |
| regulation of mRNA stability involved in response to stress | biological process | IGF2BP1 |
| regulation of multicellular organism growth | biological process | SOD1, FGFR2, PRL, APP, STAT3, IGF1, PIK3CA, PTPN11, GAMT, SOCS2, ZMPSTE24, STAT5B, HTRA2, CACNA2D2, TNKS2, MBD5, AFG3L2, GHR, MFSD2A, NPY1R, DRD3, NPPC, PRLH, STAT5A, GDF5 |
| regulation of multivesicular body size | biological process | RAB11A, RILP |
| regulation of multivesicular body size involved in endosome transport | biological process | SNF8 |
| regulation of muscle cell differentiation | biological process | CDK9, MEGF10, CAMK1 |
| regulation of muscle contraction | biological process | TPM1, ANXA6, ADRA1A, ATP1A2, MYL5, TNNI2, PPP1R12B, ADRA1B, TNNT1, KCNA1, TNNT3 |
| regulation of muscle filament sliding | biological process | MYBPC3, MYLK2 |
| regulation of muscle organ development | biological process | NEUROG1, TIFAB |
| regulation of MyD88-dependent toll-like receptor signaling pathway | biological process | IRF1, IRF7 |
| regulation of MyD88-independent toll-like receptor signaling pathway | biological process | IRF7 |
| regulation of myelination | biological process | AKT1, CTNNB1, MTOR, RARB, PTN, KIF14, NSUN5, SIRT2, DLG1, ZPR1, TYMP, PTPRZ1, LGI4, RARG, TENM4, TG, NCMAP, RARA |
| regulation of myeloid cell apoptotic process | biological process | PTEN, THRA |
| regulation of myeloid cell differentiation | biological process | FAS, CSF3R, RNF41, CREBBP, CBFB, RUNX1, PRKCB, RARG, PURB |
| regulation of myeloid dendritic cell activation | biological process | FLT3LG |
| regulation of myeloid leukocyte differentiation | biological process | NDFIP1 |
| regulation of myoblast differentiation | biological process | CAPN3, KLHL41, TRIP4, ZFP36L1, MYOCD |
| regulation of myoblast fusion | biological process | MYOG |
| regulation of myoblast proliferation | biological process | ANKRD2, KLHL41, ZNF609 |
| regulation of myofibroblast contraction | biological process | PDPN |
| regulation of myosin-light-chain-phosphatase activity | biological process | PPP1R12A, NUAK1 |
| regulation of myotube differentiation | biological process | DMPK, FBXO22, RBM24, RBM38, HDAC5, SIK1 |
| regulation of NAD(P)H oxidase activity | biological process | SLAMF8 |
| regulation of NADP metabolic process | biological process | ME1, ME2 |
| regulation of natural killer cell activation | biological process | LEP, DCAF15 |
| regulation of natural killer cell apoptotic process | biological process | BIRC7 |
| regulation of natural killer cell differentiation | biological process | PRDM1, ZNF683 |
| regulation of natural killer cell differentiation involved in immune response | biological process | ZNF683 |
| regulation of natural killer cell mediated cytotoxicity | biological process | LEP, NCR1, PIK3R6 |
| regulation of natural killer cell mediated immunity | biological process | HLA-E |
| regulation of natural killer cell proliferation | biological process | LEP, PTPN22 |
| regulation of necroptotic process | biological process | FADD, CFLAR, BIRC2, CYLD |
| regulation of necrotic cell death | biological process | CASP8, PPIF, OLFM4 |
| regulation of negative chemotaxis | biological process | PLXNA4 |
| regulation of nephron tubule epithelial cell differentiation | biological process | CTNNB1, GATA3 |
| regulation of nerve growth factor receptor activity | biological process | CAV3 |
| regulation of nervous system development | biological process | RTN4, GBX1, GRN, GBX2 |
| regulation of nervous system process | biological process | ROCK2, HTR2C |
| regulation of neural precursor cell proliferation | biological process | FOXO1, NF2, SIX3, SHCBP1, FOXG1, TRIM71, ID2, FOXO3 |
| regulation of neural retina development | biological process | SIX3, PTF1A |
| regulation of neuroblast proliferation | biological process | SIX3, LRRK2 |
| regulation of neurogenesis | biological process | EZH2, CTNNB1, CHD7, NF2, HES1, ASCL2, HES6, BHLHE40, NOTCH1, PER2, ZNF335, ASCL1, HES7, DOCK7, CX3CR1, YAP1, HEY2, YTHDF2, POU4F1, ARNTL, PRUNE1, HEY1, DLL1, HOXB3, WNT3, BHLHE41, HES2 |
| regulation of neuroinflammatory response | biological process | CD200R1, DAGLA, MMP8 |
| regulation of neuron apoptotic process | biological process | ESR1, BAX, ESR2, GPX1, NSMF, PARK7, G6PD, TP63, LANCL1, GRM4, GRIN1, NAE1, KIF14, TRIM2, GATA3, GABRB3, MEF2C, GABRA5, PINK1, GABRB2, FAIM2, GRID2, EGLN2, SIGMAR1, AKT1S1, PCSK9, TP53 |
| regulation of neuron death | biological process | APOE, CLU, CCL5, TBK1, RAB29, DHCR24, TSC1, SARM1, EPHB1, RRAS2, CHRNA7, DCC, CHP1, EGLN1, CTSZ, GPR75, UBB, RILPL1, LRRK2 |
| regulation of neuron differentiation | biological process | NGF, DPYSL2, CDK5RAP1, YWHAH, ALK, LTK, CDK5RAP2, CDK5RAP3, NTF4, NEUROG1, ZFHX3, BCL11B, ROCK1, CDON, NEUROD1, CDK5R1, FGF20, NREP, SIX1, YWHAG, ID2, S1PR5, EYA1, NTF3, CASZ1, BIN1, EFNA3 |
| regulation of neuron maturation | biological process | RAC3, LRRK2 |
| regulation of neuron migration | biological process | NSMF, SHTN1, CAMK2B, CTNNA2, SCRT1, NTNG1, FLRT2, PHACTR1, KIF20B, UNC5D, ULK4, NTNG2, LRIG2, IGSF10, PLXNB2, SCRT2, CAMK2A, ZSWIM6 |
| regulation of neuron projection arborization | biological process | MACF1, NTNG1, MYO9A, MFSD2A, NTNG2, MOV10 |
| regulation of neuron projection development | biological process | AKT1, GSK3B, PTEN, IL1RAPL1, EFHC2, PTPRF, DPYSL3, RGMA, CTNNA2, CCDC88A, SLC39A12, DISC1, NTNG1, GATA3, TBR1, FRMD7, NRCAM, PSEN1, SNAP25, ULK4, NCS1, NTNG2, ARF6, SFRP2, GRID2, PAK3, CAMK2G, FBXO7, ACAP3, BRSK1, KLK6, MARK1, ZNF804A |
| regulation of neuron projection regeneration | biological process | PRRX1 |
| regulation of neuronal action potential | biological process | IFNG, FMR1, FGF12 |
| regulation of neuronal signal transduction | biological process | CLU |
| regulation of neuronal synaptic plasticity | biological process | APOE, GSK3B, NSMF, GRIN1, STAR, EPHB2, JPH3, SYP, CNTN2, NCDN, MCTP1, EGR2, ZDHHC2, S100B, ACP4, RASGRF1, CAMK2A, NETO1 |
| regulation of neurotransmitter levels | biological process | GABRA2, DVL1, ZNF219, PDE1B, HRH3 |
| regulation of neurotransmitter receptor activity | biological process | FNTA, LYPD6, LYNX1, LYPD6B, PSCA, CDK5 |
| regulation of neurotransmitter receptor localization to postsynaptic specialization membrane | biological process | GHSR, GPC6, PRKCZ, GPC4, HRAS, DAG1 |
| regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane | biological process | GRIPAP1, ARHGAP44 |
| regulation of neurotransmitter secretion | biological process | FMR1, SNCAIP, RIMS1, CPLX1, PRKN, MCTP2, MEF2C, SYN1, SYT12, KCNC4, MCTP1, RHOT1, HCRT, KCNMB4, CAMK2A, CHRNB4, CPLX2, CPLX3, SNCG |
| regulation of neurotransmitter uptake | biological process | ARL6IP5, FLOT1, DRD3, DRD2 |
| regulation of neurotrophin TRK receptor signaling pathway | biological process | SLC9A6, DOK5 |
| regulation of neutrophil chemotaxis | biological process | JAM3, BST1, MPP1 |
| regulation of neutrophil degranulation | biological process | SYK, PRAM1 |
| regulation of neutrophil mediated cytotoxicity | biological process | DNASE1L3, DNASE1 |
| regulation of neutrophil mediated killing of gram-negative bacterium | biological process | CXCL6 |
| regulation of neutrophil migration | biological process | RHOG, RAC1, RAC2 |
| regulation of NF-kappaB import into nucleus | biological process | PRDX1 |
| regulation of NIK/NF-kappaB signaling | biological process | EZR, BCL3, RELA, AKIP1, PTPN22, NFKBIA, BIRC2, RASSF2, DLG1, EDA, LIME1, TRIM6, AGER |
| regulation of nitric oxide biosynthetic process | biological process | JAK2, CD47, NOS1AP, RAC1, CX3CR1, PTK2B |
| regulation of nitric oxide mediated signal transduction | biological process | PDE5A |
| regulation of nitric oxide metabolic process | biological process | SELENOS |
| regulation of nitric-oxide synthase activity | biological process | EGFR, IL1B, NOS3, NOSTRIN, HSP90AA1, AKT1, LEP, WASL, DDAH1, NOS1AP, LYPLA1, SPR, CALM1, ZDHHC21, NOSIP, DDAH2, ACVR2A, CYGB, CAV1 |
| regulation of nitrogen compound metabolic process | biological process | BCR |
| regulation of nitrogen utilization | biological process | BCL2, BAX |
| regulation of NK T cell differentiation | biological process | PRDM1, ZNF683 |
| regulation of NLRP3 inflammasome complex assembly | biological process | EIF2AK2 |
| regulation of NMDA receptor activity | biological process | GRIN1, NRXN1, PPARGC1A, CRH, MEF2C, CRHBP, ACTN2, GRIA2, DLG1, GRIN2B, CAPN1, DAPK1, DLG4, DLG3, GRIA3, CNIH2, GRIN2A, GRIA1, MAPK8IP2, RASGRF1, PTK2B, DLG2, RELN, NEFL |
| regulation of nodal signaling pathway | biological process | DMRT1, DACT1 |
| regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry | biological process | SHH |
| regulation of non-canonical Wnt signaling pathway | biological process | TIAM1, DAAM2, GPC3 |
| regulation of non-motile cilium assembly | biological process | BBS4 |
| regulation of norepinephrine secretion | biological process | FFAR3, HRH3, ADORA2A, AGT |
| regulation of norepinephrine uptake | biological process | SNCA |
| regulation of Notch signaling pathway | biological process | IL6ST, CD46, SREBF2, NOTCH1, POSTN, DTX1, ASCL1, MFNG, LLGL1, YJEFN3, TSPAN15, LLGL2, POGLUT1, GALNT11, POFUT1, GAS2, PRAG1, LFNG, TSPEAR, SYNJ2BP |
| regulation of nuclear cell cycle DNA replication | biological process | TIPIN, NUGGC, DACH1 |
| regulation of nuclear migration along microtubule | biological process | TRIM58 |
| regulation of nucleic acid-templated transcription | biological process | DDX1, LPXN, PIR, PXN, AIP, TRIP13, PTPN14, SND1, RALY, ACTN4, TCERG1L |
| regulation of nucleocytoplasmic transport | biological process | PPP1R12A, RBM4, MX2, AAAS, NUP214 |
| regulation of nucleotide-binding oligomerization domain containing signaling pathway | biological process | XIAP, BIRC2 |
| regulation of nucleotide-excision repair | biological process | RAD52 |
| regulation of nucleus organization | biological process | NFE2L1 |
| regulation of nucleus size | biological process | HP1BP3 |
| regulation of odontoblast differentiation | biological process | NFE2L1 |
| regulation of odontogenesis | biological process | SHH, MSX1, SP6 |
| regulation of odontogenesis of dentin-containing tooth | biological process | BMP4, FGF8, WNT10A, DMRT3, RUNX2, BMP2, APCDD1 |
| regulation of oligodendrocyte differentiation | biological process | WDR1, TNFRSF21, OPALIN |
| regulation of oligodendrocyte progenitor proliferation | biological process | EMX1, PTPRZ1 |
| regulation of opioid receptor signaling pathway | biological process | PPP1R9B, SYP |
| regulation of opsonization | biological process | C4BPB |
| regulation of organ growth | biological process | SOD1, STRA8, MAEL, FLVCR1, BCL2L11, LATS2, SAV1, FOXC2, LATS1, FOXC1 |
| regulation of organelle assembly | biological process | EZR, MSN, RDX |
| regulation of organelle organization | biological process | CAMSAP2, CAMSAP3 |
| regulation of organelle transport along microtubule | biological process | NEFH, MAP2, RHOT1, LAMP1, HAP1 |
| regulation of ossification | biological process | CSF1, DHRS3, ACVR1, INTU, LRP6, PBX1, EGR2, PTGER4, ESRRA, SIX2, RUNX2 |
| regulation of osteoblast differentiation | biological process | FGFR2, CTNNB1, PTK2, REST, HEMGN, ATF4, RASSF2, ESRRA, GLI1, RUNX2, TCIRG1, SMOC1 |
| regulation of osteoblast proliferation | biological process | FGFR2, NPR3 |
| regulation of osteoclast development | biological process | TYROBP, SIGLEC15 |
| regulation of osteoclast differentiation | biological process | FSHB, TNF, FSHR, BGLAP, CTNNB1, MTOR, CAMK4, MITF, RASSF2, PRXL2A, TFE3, UBASH3B, ESRRA |
| regulation of ovarian follicle development | biological process | GNRH1, UMODL1 |
| regulation of oxidative phosphorylation | biological process | COX7A2L, SLC25A33, COX7A2, AK4, PINK1, SHMT2, ATP7A, UQCC2, COX7A1, ABCD1, SLC25A23 |
| regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | biological process | P4HB |
| regulation of oxidative stress-induced neuron death | biological process | LANCL1, REST |
| regulation of oxidoreductase activity | biological process | ECSIT |
| regulation of oxygen metabolic process | biological process | RNF34 |
| regulation of p38MAPK cascade | biological process | HGF, PER1, LGALS9, DAB2IP, RASGRP1, CAV3, ULK4, PHLPP1, AGER |
| regulation of parathyroid hormone secretion | biological process | GNAS |
| regulation of pathway-restricted SMAD protein phosphorylation | biological process | BMP7, BMP4, PIN1, BMPER |
| regulation of penile erection | biological process | CNR1 |
| regulation of pentose-phosphate shunt | biological process | PGAM1, PGAM4, TIGAR |
| regulation of peptidase activity | biological process | CAV1 |
| regulation of peptide hormone secretion | biological process | FFAR3 |
| regulation of peptidyl-serine phosphorylation | biological process | NSD1, PLCL1, HRC, SPTBN4, PLCL2 |
| regulation of peptidyl-tyrosine phosphorylation | biological process | EGFR, EGF, PRNP, IL7, EFNA1, PDGFD, PDGFA, PRKCE, TREM2, ITGB2, TMEM102, PDGFRB, BST1, EPHA7, PDGFC, HRG |
| regulation of PERK-mediated unfolded protein response | biological process | HSPA5 |
| regulation of peroxisome organization | biological process | DNM1L, MFF, MAVS |
| regulation of peroxisome size | biological process | PEX11B, PEX11G, PEX11A |
| regulation of pH | biological process | SLC26A4, ATP6V1B1, PDK4, SLC9A2, SLC9A1, SLC9A7, SLC9A9, EDNRB, CLCN3, ATP6V0A4, SLC9A6, EDN1, RHCG, PDK2, SLC4A10 |
| regulation of phagocytosis | biological process | ITGAV, SYK, SCARB1, PTPRC, OLFM4, FGR, HCK, PRKCG, SYT7 |
| regulation of phagosome maturation | biological process | CLN3 |
| regulation of phenotypic switching | biological process | MYOCD |
| regulation of phenotypic switching by transcription from RNA polymerase II promoter | biological process | SP1 |
| regulation of phosphatase activity | biological process | CDK5RAP3 |
| regulation of phosphate transport | biological process | ROS1, FGF23 |
| regulation of phosphatidylcholine biosynthetic process | biological process | FABP3 |
| regulation of phosphatidylcholine catabolic process | biological process | LDLR, SCARB1 |
| regulation of phosphatidylcholine metabolic process | biological process | MFSD2A |
| regulation of phosphatidylethanolamine metabolic process | biological process | MFSD2A |
| regulation of phosphatidylinositol 3-kinase activity | biological process | KLF4, CISH, SOCS2, PIK3R1, SOCS5, SOCS4, SOCS1, WDR91, WDR81, SLA2, PIK3R3, SOCS7, SOCS6, PIK3R2, PIK3R6, PIK3R5, SOCS3 |
| regulation of phosphatidylinositol 3-kinase signaling | biological process | EGFR, EGF, KITLG, ERBB2, FGFR2, FGFR3, MAPK3, MAPK1, AKT1, FGFR1, KIT, PIK3CA, NRG1, FGF17, FGF8, PTPN11, FGF3, FGF9, CEP55, PPP2R5C, RASGRP1, PIP5K1A, ENTPD5, PIP4K2A, PTPN13, PIP5K1B, PPP1R16B, PIP4K2C, PIP4K2B, DIPK2A, CEACAM1, IER3, LIME1, FBXL2, PIP5K1C |
| regulation of phosphatidylinositol dephosphorylation | biological process | MTMR4, MTMR9, MTMR1, MTMR3, CHRM5 |
| regulation of phosphatidylserine metabolic process | biological process | MFSD2A |
| regulation of phospholipase A2 activity | biological process | PPT1, LRP1 |
| regulation of phospholipase activity | biological process | SNCA |
| regulation of phospholipid biosynthetic process | biological process | IDH1 |
| regulation of phospholipid catabolic process | biological process | IDH1 |
| regulation of phospholipid metabolic process | biological process | GNB3, ARF1 |
| regulation of phosphoprotein phosphatase activity | biological process | PPP2R2B, PPP2R3A, PPP2R5A, PPP1R7, PPP4R1, PPP1R2, PPP2R2A, HSP90B1, PPP2R1B, RCAN2, PPP6R2, PPP2R5C, SHOC2, TSC1, PPP2R2C, PPME1, ARPP19, PPP1R8, PPP2R5E, PHACTR1, PPP2R5D, PPP6R3, TIPRL, ANKLE2, PPP4R2, PPP1R3B, PPP1R16B, PPP2R2D, RCAN3, IGBP1, PPP1R16A, EIF2AK2, HTT, RCAN1, SET, PHACTR4, PHACTR3, DRD2, PPP2R1A, B3GAT3 |
| regulation of phosphorus metabolic process | biological process | FAM20C |
| regulation of phosphorylation | biological process | IL4, BMP7, PPP1R14A, PPP1R14C, SRPX2, SIRT2, RAD17, PSEN1, BARD1, IKBKB, MCM7, ENG, RPTOR |
| regulation of phosphorylation of RNA polymerase II C-terminal domain | biological process | BRD4, PPIL4 |
| regulation of planar cell polarity pathway involved in neural tube closure | biological process | NPHP3 |
| regulation of plasma lipoprotein particle levels | biological process | DGAT2, LPCAT3 |
| regulation of plasma membrane bounded cell projection organization | biological process | TREM2 |
| regulation of plasma membrane repair | biological process | SYTL4, MYH9 |
| regulation of plasma membrane sterol distribution | biological process | ARV1 |
| regulation of platelet activation | biological process | SYK, TEC, FCER1G, HRG |
| regulation of platelet aggregation | biological process | SYK, CELA2A, PRKCQ, LYN |
| regulation of platelet-derived growth factor production | biological process | NDRG2 |
| regulation of platelet-derived growth factor receptor signaling pathway | biological process | LRIG2 |
| regulation of platelet-derived growth factor receptor-alpha signaling pathway | biological process | CBL, CBLB |
| regulation of platelet-derived growth factor receptor-beta signaling pathway | biological process | LOX |
| regulation of podosome assembly | biological process | SRC, KIF9, HCK |
| regulation of polarized epithelial cell differentiation | biological process | AJAP1 |
| regulation of positive thymic T cell selection | biological process | FOXN1 |
| regulation of postsynapse organization | biological process | HSPA8, ARF4, SEMA3F, DGKB, GHSR, ARHGAP22, LRFN2, NRCAM, NRP2, SRGN, CDKL5, ABHD17B, EGLN1, EPHA7, ABHD17A, WNT7A |
| regulation of postsynaptic cytosolic calcium ion concentration | biological process | FZD9, MYO5A, CALB1, SLC8A3, SLC8A1, ITPR1, GRIA1, ATP2B2, SLC8A2, GRM5, GRM1 |
| regulation of postsynaptic density assembly | biological process | LRFN4, LRRTM1, IL1RAP, LRRC4B, GRID2, PTPRS, LRRTM2, LRFN1, PTPRD |
| regulation of postsynaptic density protein 95 clustering | biological process | CRIPT, ZMYND8 |
| regulation of postsynaptic membrane neurotransmitter receptor levels | biological process | ERBIN, CACNG2, CTNND1, YWHAE, EPS8, DLG3, EFNB2, CPT1C, FRRS1L |
| regulation of postsynaptic membrane organization | biological process | RAPSN |
| regulation of postsynaptic membrane potential | biological process | CATSPER4, GABRB1, CHRNA5, GABRA2, CHRNE, KCND2, CHRNA2, GABRG2, CHRNB1, GABRA5, CHRNA7, CHRND, CHRNA10, GABRB2, GABRA4, GABRG1, GRIA2, GRIK3, GABRD, CHRNA6, GRIN3A, GABBR1, ADRB1, GABRR2, GRIA3, CDK5, GRIK4, CHRNG, CHRM1, GABRA1, GRIN2A, GRIN3B, CHRNB2, GABRA3, GRIA1, KCNA1, GRID1, GRIK1, GRM5, FGF14, GABRG3, CHRNA1, GLRA2, CHRNB4, GRM1 |
| regulation of postsynaptic neurotransmitter receptor activity | biological process | NPTX1, AKAP9, NPTX2, HOMER1, CACNG4, CNIH2, BEGAIN, SHISA7, NPTXR, SHISA6 |
| regulation of postsynaptic neurotransmitter receptor internalization | biological process | NUMB, GSG1L, HPCA, SCRIB, ITGB3, OPHN1, DRD3, EFNB2, DRD4, ATAD1 |
| regulation of postsynaptic specialization assembly | biological process | GAP43 |
| regulation of potassium ion export across plasma membrane | biological process | DLG1 |
| regulation of potassium ion import | biological process | DLG1 |
| regulation of potassium ion transmembrane transport | biological process | DPP6, PRNP, KCNAB1, KCNH2, KCNIP4, CD63, KCNIP1, KCNAB3, KCNE1, KCNIP2, KCNC1, CACNA1D, KCNAB2, KCNIP3, KCNN2, RGS4 |
| regulation of potassium ion transmembrane transporter activity | biological process | KCNAB1, FHL1, NEDD4, YWHAE, NEDD4L, WWP2, CACNA1D |
| regulation of potassium ion transport | biological process | ANK3, DRD3, DRD2, GCK, KCNE3 |
| regulation of presynapse assembly | biological process | LRFN4, LRFN5, MDGA1, SNCA, LRRTM1, WNT3A, IL1RAP, GPC6, SLITRK4, SLITRK5, LRRC4B, SLITRK1, SLITRK6, NTNG2, ARF6, CBLN2, GPC4, SLITRK3, LRFN3, SLITRK2, CLSTN3, FZD1, WNT7A, PTPRD, VPS35 |
| regulation of presynaptic cytosolic calcium ion concentration | biological process | P2RY4, CALB1, NCS1, ATP2B3, P2RY1, HTR1B, ATP2B1, ATP2B2 |
| regulation of presynaptic membrane potential | biological process | GRIK3, KCNC1, KCNC2, KCNA1, GRIK2 |
| regulation of primitive erythrocyte differentiation | biological process | GATA2, GATA1 |
| regulation of pro-B cell differentiation | biological process | SOS1, FNIP1, FLCN |
| regulation of production of miRNAs involved in gene silencing by miRNA | biological process | TARBP2 |
| regulation of production of siRNA involved in RNA interference | biological process | TARBP2 |
| regulation of progesterone biosynthetic process | biological process | EGR1, DGKQ |
| regulation of progesterone secretion | biological process | GDF9 |
| regulation of programmed cell death | biological process | BCL2, CXCR4, BNIP3L, BNIP3, ACER3 |
| regulation of pronephros size | biological process | HNF1A, HNF1B |
| regulation of prostaglandin biosynthetic process | biological process | FABP5 |
| regulation of prostaglandin catabolic process | biological process | HPGD |
| regulation of prostatic bud formation | biological process | SHH |
| regulation of proteasomal protein catabolic process | biological process | GPX1, PKD1, USP14, PSMD14, NUDT15, BTRC, PSME1, RHBDF1, DNAAF4, PINK1, NFE2L1, UCHL5, UBB |
| regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | RAD23A, RAD23B, GBA, DDA1, XPO1, GNA12, DESI1, COMMD1, UBE2K, FOXF2, WNT10B, UBQLN4 |
| regulation of protein ADP-ribosylation | biological process | WARS1, ADNP, HPF1, PUM3, KAT2B |
| regulation of protein autophosphorylation | biological process | PPP2R5A, EEF2K, PPP2R5C, MOB1B, PPP2R5E, PPP2R5D, EPHA7 |
| regulation of protein autoubiquitination | biological process | SASH1 |
| regulation of protein binding | biological process | APP, TGFBR3, SRC, HDAC4, LRRC6, DZIP1, SNAPIN, SMARCD3, PSEN1, CDON, PRMT8, PLK1, ANGPT1, CYLD, BTBD1, TGFBR1, UBASH3B, CRK, HDAC5, CAMK1, PRMT7, PCBD1 |
| regulation of protein catabolic process | biological process | MDM2, CDC42, PSMD1, XPO1, FAM83D, HGS, ODC1, UBXN2A, CHMP6, NEDD4L, PSMD2, SNF8, ZDHHC2, FAF1, PSMD3, ARNTL, FURIN |
| regulation of protein catabolic process at postsynapse, modulating synaptic transmission | biological process | RNF19A, EGLN1 |
| regulation of protein catabolic process at presynapse, modulating synaptic transmission | biological process | RAB26, PLEKHG5, FBXL20 |
| regulation of protein complex assembly | biological process | HSP90AA1, PTPN11, HSPA8, DAB2IP, HCFC1, HJURP, AIDA, NCLN, PINK1, INSM1, LATS1, IRGM, ANKRA2, HRG, GFAP, TRAF2, CD36, TICAM1 |
| regulation of protein complex stability | biological process | HSPA8, SCOC, TRAPPC11, ECSIT, SQSTM1, NCLN, TAPBP, SNF8, IRGM, TREX1 |
| regulation of protein deacetylation | biological process | SPRED1, CCAR2 |
| regulation of protein dephosphorylation | biological process | PPP1R16B, PPP1R16A |
| regulation of protein depolymerization | biological process | ASPH |
| regulation of protein deubiquitination | biological process | ITCH |
| regulation of protein exit from endoplasmic reticulum | biological process | GCC2 |
| regulation of protein export from nucleus | biological process | CDKN2A, PTPN11, XPO1, UHMK1, IFI27, TPR, SIRT7, PTPN14 |
| regulation of protein folding in endoplasmic reticulum | biological process | HSPA5 |
| regulation of protein glycosylation | biological process | MT3, FKTN, ABCA2 |
| regulation of protein heterodimerization activity | biological process | BCL2, BAX, BAK1, NRG1, CDC42, ZNF268 |
| regulation of protein homodimerization activity | biological process | BCL2, BAX, BAK1, NRG1 |
| regulation of protein import | biological process | HSPA8 |
| regulation of protein import into nucleus | biological process | TGFB1, BMP4, NUP58, NUP62, NUP54, TPR |
| regulation of protein import into nucleus, translocation | biological process | OGG1 |
| regulation of protein K48-linked deubiquitination | biological process | OTUD4 |
| regulation of protein K63-linked ubiquitination | biological process | SASH1 |
| regulation of protein kinase A signaling | biological process | FSHR, AKAP4, PJA2, AKAP12, PRKAR2A, AIP, AKAP7, AKAP1, PRKAR2B, PDE10A, PRKAR1B, AKAP5, LRRK2, PDE4A, AKAP6 |
| regulation of protein kinase activity | biological process | SOD1, MTOR, CSNK2B, CDC42, CCNYL1, TSPYL2, SLC9A3R1, ELP4, SMG8, TSC1, GCN1, TTN, PLCE1, ECT2, RAC2, TRPT1, FAF1, FGR, ANKRD54, PRKAR2B, ELP3, CAMKK2, CDC37 |
| regulation of protein kinase B signaling | biological process | MTOR, SESN3, INPP5F, RNF41, RRAS, NTRK2, CAV3, GRM2 |
| regulation of protein kinase C signaling | biological process | AKAP12, ULK4, SEZ6L, SEZ6 |
| regulation of protein lipidation | biological process | RABL3 |
| regulation of protein localization | biological process | BCL2, AKT1, MAPK8, TEX15, SUMO1, WASL, SYCP1, SLC26A4, PRNP, RAB9A, BORA, TRIM17, FBXW7, STX10, RACK1, TRIM58, NKX3-1, TBC1D1, B9D1, SWAP70, PICALM, CEP120, MMD, RAB14, DZIP1L, CELSR2, ITGB3, AAK1, TRIM38, MYCBP2, RABGAP1L, TPR, SIX1, ARHGDIG, SIX4, TRIM21, RAB8A, DNAJB2, INS, PTCH1, PLEKHM2, MMD2, CELSR3, RSL1D1, CAMK1, ATCAY, AFDN, TRIM6, TRIM5, TRIM22 |
| regulation of protein localization to adherens junction | biological process | VCL |
| regulation of protein localization to cell cortex | biological process | PLK1, MISP |
| regulation of protein localization to cell periphery | biological process | ABCA2 |
| regulation of protein localization to cell surface | biological process | EGF, CTNNB1, HFE, RAB11FIP5, RAB11B, GBF1, KCNAB2, ABCA2 |
| regulation of protein localization to cell-cell junction | biological process | ZDHHC7 |
| regulation of protein localization to centrosome | biological process | CEP72 |
| regulation of protein localization to cilium | biological process | CCDC66 |
| regulation of protein localization to membrane | biological process | GPC2, GPC5, GPC6, GPC4, GPC1, GPC3 |
| regulation of protein localization to nucleolus | biological process | GLUL, NVL |
| regulation of protein localization to nucleus | biological process | LEP, SHH, NF2, SUMO3, PIN1, ATP13A2, RASSF5 |
| regulation of protein localization to plasma membrane | biological process | PIK3R1, STX8, VTI1B, VAMP8, SPTBN1, STX7, GBP1, MMP14, CSRP3, ZDHHC2, CLN3, ZDHHC7, CDK5, APPL1, INS |
| regulation of protein localization to synapse | biological process | DLG1, ABHD17B |
| regulation of protein metabolic process | biological process | CDC42, SENP2, ROCK2, LDLR, PDCD4, GHRHR, TRIM71, WNT10B |
| regulation of protein monoubiquitination | biological process | WDR48 |
| regulation of protein oligomerization | biological process | DNM1L |
| regulation of protein phosphorylation | biological process | TNF, EZH2, LEP, FN1, TADA3, GJC2, PRKAR2A, PPP2CA, CCNYL1, PIN1, PPP1R9B, NDUFS4, CORO1C, DVL1, PTK2, PHIP, ITPKB, CCDC88A, WNT9B, SOCS1, KDM4D, RIT2, SMPD3, ROPN1B, APOA1, LOX, FNIP2, HUS1, FER, CCDC88C, LYN, PML, FNIP1, FLCN, PIK3CG, STAT2, DRD1, PRKAR2B, CDH5, TLR7, PRKAR1B, SESN2, PLXNB2, LRP4, ARRB2, CELSR3, GRM5, SOCS3, HSPB1 |
| regulation of protein polyubiquitination | biological process | FOXF2 |
| regulation of protein processing | biological process | IFT52, PRKACB, RNF139, INPP5B, CLN3 |
| regulation of protein secretion | biological process | TNF, SAA1, PAM, DNAJC1, RHBDF1, STXBP5, PIK3C3, KRT20, LLGL1, ARFIP1, LLGL2, P3H1, INS, RHBDF2, STXBP5L |
| regulation of protein serine/threonine kinase activity | biological process | PRKAG2, UVRAG |
| regulation of protein serine/threonine phosphatase activity | biological process | PPP4R4 |
| regulation of protein stability | biological process | BCL2, TERT, MAPK1, CDKN2A, TF, PTEN, KHDRBS1, CDC42, SUMO1, NF2, TADA3, HSPA8, TRIM24, GNL3L, RNF149, USP3, PIN1, SH3GLB1, XBP1, LSS, CD81, APTX, GIPC1, KRAS, PRKD1, USP28, SUGT1, PRKN, FBXO4, STUB1, ASGR2, HDAC8, LAMP2, GGA3, CTSA, DDOST, CMTM6, TOMM7, ANK2, SIAH3, CCAR2, ATF7IP, NEDD4L, USP36, ADGRV1, USP7, TPR, SOX4, ASPH, USP4, HDAC3, B4GALT5, DACT1, HDAC6, SREBF1, CDKN2AIP, DPM2, TMEM25, RNF128, QRSL1, PYCARD, DAD1, KAT2A, MUL1, SLC51B, FBXO7, DDI1, SEPTIN8, FAM107A, PINX1, LRRK2, VPS35 |
| regulation of protein sumoylation | biological process | ZMIZ1, EGR1 |
| regulation of protein targeting | biological process | NUCB1 |
| regulation of protein targeting to mitochondrion | biological process | CDKN2A, PARL, HAX1, PRKN, BNIP3L, ATP5IF1, PINK1, SREBF1 |
| regulation of protein targeting to vacuolar membrane | biological process | VAMP7 |
| regulation of protein transport | biological process | RAB11A, SCFD1, GAPVD1, RAB8A |
| regulation of protein tyrosine kinase activity | biological process | RAP2B, PTPRC |
| regulation of protein ubiquitination | biological process | HSP90AA1, HSPA1A, HSPA1B, SIAH2, FBXO2, PRKN, UBXN2A, HERPUD1, PINK1, TGFBR1, MTBP, DNAJB2 |
| regulation of protein-containing complex disassembly | biological process | IRAK3 |
| regulation of proteinase activated receptor activity | biological process | BICD1 |
| regulation of proteolysis | biological process | PLAUR, SHH, PARL, TRAF3, NEDD8, SPOP, C2CD3, GSAP, LTBP4 |
| regulation of proton transport | biological process | IL4, NOX5, SLC30A5, IL13, TCIRG1 |
| regulation of proton-transporting ATPase activity, rotational mechanism | biological process | PPIF |
| regulation of purine nucleotide metabolic process | biological process | LACC1 |
| regulation of Purkinje myocyte action potential | biological process | GJA5 |
| regulation of pyruvate dehydrogenase activity | biological process | SIRT4 |
| regulation of pyruvate kinase activity | biological process | JMJD8 |
| regulation of Rab protein signal transduction | biological process | DENND1A, MADD, SGSM3, DENND4B |
| regulation of Rac protein signal transduction | biological process | OGT, ARHGAP17, SSX2IP, ARF6, CRK, SH3BP1, RASGRF1, ARHGAP44 |
| regulation of Ral protein signal transduction | biological process | RALGPS1, RALGPS2, RGL2 |
| regulation of Rap protein signal transduction | biological process | TIMP2, KIF14, CBL, RDX |
| regulation of Ras protein signal transduction | biological process | FOXM1, NUP62, RABL3, SQSTM1, PLCE1, FLCN, RASGRF2, RASGRF1 |
| regulation of reactive oxygen species biosynthetic process | biological process | SPHK2, CCN6, SLC25A33, SNCA, UCP1, ALOX5 |
| regulation of reactive oxygen species metabolic process | biological process | TNF, FOXO1, CYP1B1, FOXM1, ARF4, PARL, PDK3, STK17A, RNF41, PRKN, PRCP, BCO2, PID1, ATG5, PINK1, BIRC2, TUSC2, EIF6, RIPK3, FOXO3, MPV17, COQ7 |
| regulation of receptor activity | biological process | SERPINE1, PLAU, TAFA4, FCGR2B, HMGB1, PRKCD, PDE4D, MUC4, P2RY1, CNRIP1, MAPK8IP2, PCSK9 |
| regulation of receptor binding | biological process | LOX |
| regulation of receptor biosynthetic process | biological process | ANKRD13C |
| regulation of receptor internalization | biological process | SH3GL2, ARF1, DKK1, FLOT1 |
| regulation of receptor localization to synapse | biological process | NPTN |
| regulation of receptor recycling | biological process | CHMP5, KIF16B, LAMTOR1, TBC1D16 |
| regulation of receptor signaling pathway via JAK-STAT | biological process | JAK2, ELP2, HES1, SOCS1, PTPRC, DOT1L, PIGU, JAK3 |
| regulation of receptor-mediated endocytosis | biological process | LRPAP1, CD2AP |
| regulation of recycling endosome localization within postsynapse | biological process | GRIPAP1 |
| regulation of regulated secretory pathway | biological process | SYT1, MICAL1 |
| regulation of regulatory T cell differentiation | biological process | TGFB1, FANCA, FANCD2, CBFB, CTLA4, RUNX1, NFATC2, TNFRSF18, KAT2A, CD28 |
| regulation of relaxation of cardiac muscle | biological process | CAMK2D, PLN |
| regulation of relaxation of muscle | biological process | SRI, SLN, PLN |
| regulation of release of sequestered calcium ion into cytosol | biological process | TRDN, CASQ2, PTPN6, CYBA, DIAPH1, ATG5, ANK2, LYN, UBASH3B, PRKCE, LIME1, CORO1A, CASQ1, PTK2B |
| regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | biological process | CAMK2D, SRI, DMD, METTL21C, TRDN, CASQ2, GSTO1, CALM1, CALM2, CALM3, PLN, FKBP1B, PDE4D, ASPH, HRC, CASQ1, AKAP6 |
| regulation of removal of superoxide radicals | biological process | NFE2L2, BMP7, FBLN5, DHFR, GCH1, CD36 |
| regulation of renal output by angiotensin | biological process | ACE, AGT |
| regulation of renal sodium excretion | biological process | AGTR1, AVP, AGT |
| regulation of renin secretion into blood stream | biological process | GJA5 |
| regulation of replicative cell aging | biological process | NEK4 |
| regulation of respiratory burst | biological process | NOXO1, NOXA1, RAC1, RAC2 |
| regulation of respiratory gaseous exchange | biological process | GRIN1, PASK, NR4A2, PHOX2A, GLRA1, NTSR1 |
| regulation of respiratory gaseous exchange by nervous system process | biological process | PHOX2B, PBX3, NLGN2, ATP1A2, MECP2, TSHZ3, GLRA1, GLS |
| regulation of respiratory system process | biological process | MTG1 |
| regulation of response to DNA damage checkpoint signaling | biological process | TIGAR |
| regulation of response to DNA damage stimulus | biological process | CASP9, MCL1, NPAS2, USP51, ING2, SMG1, ARMT1, ABL1, NEK4, IER3 |
| regulation of response to drug | biological process | ADIRF, GABRA4 |
| regulation of response to endoplasmic reticulum stress | biological process | MANF, NUPR1, NFE2L1 |
| regulation of response to food | biological process | GHRL, MTOR, MT3, PRKCG |
| regulation of response to osmotic stress | biological process | MLC1 |
| regulation of response to oxidative stress | biological process | STOX1, MACROH2A1 |
| regulation of response to reactive oxygen species | biological process | SESN3, HEBP2, SESN2 |
| regulation of resting membrane potential | biological process | KCNJ10, PSEN1, ATP1A3, TREM2, KCNJ2, KCNK1, NALCN, KCNK6 |
| regulation of restriction endodeoxyribonuclease activity | biological process | HMGB1 |
| regulation of retina development in camera-type eye | biological process | CELF4 |
| regulation of retinal cell programmed cell death | biological process | CNTF |
| regulation of retinal ganglion cell axon guidance | biological process | VEGFA, POU4F2, NRP1 |
| regulation of retinoic acid receptor signaling pathway | biological process | AKR1C3, CYP26B1, DHRS3, SNW1, CRABP2 |
| regulation of retrograde protein transport, ER to cytosol | biological process | BRSK2 |
| regulation of retrograde trans-synaptic signaling by endocanabinoid | biological process | FABP5 |
| regulation of retrograde transport, endosome to Golgi | biological process | RAB29, LRRK2 |
| regulation of retrograde vesicle-mediated transport, Golgi to ER | biological process | BET1L, RAB33B |
| regulation of Rho guanyl-nucleotide exchange factor activity | biological process | CCPG1, PBXIP1 |
| regulation of Rho protein signal transduction | biological process | ARHGDIA, RAF1, SOS1, PDCD10, ARHGEF10, KALRN, KANK2, DLC1, BCR, STARD13, FLOT1, EPS8, ARHGEF28, CDC42SE2, ARHGEF2, AKAP13, ARHGDIB, RASGRF2, OPHN1, ARHGEF25, CDC42SE1, MYO9B, ARHGEF18, EPS8L1, RASGRF1 |
| regulation of Rho-dependent protein serine/threonine kinase activity | biological process | SYNPO2, THY1 |
| regulation of rhodopsin gene expression | biological process | NRL, RPE65 |
| regulation of rhodopsin mediated signaling pathway | biological process | FNTA, METAP2, GRK4, PDE6A, GUCY2F, PPEF1, CALM1, GUCA1A, SAG, NMT1, PDE6G, FNTB, GUCY2D, AIPL1, CAMKMT, CNGB1, GRK7, PDE6B, RHO, GRK1, NMT2, GUCA1C, METAP1 |
| regulation of ribonuclease activity | biological process | OAS1, OASL, OAS2 |
| regulation of ribosomal DNA heterochromatin assembly | biological process | NAA40, MACROH2A1 |
| regulation of RIG-I signaling pathway | biological process | BIRC2 |
| regulation of RNA biosynthetic process | biological process | NCOA3, WNT3A, MITF, NCOA1 |
| regulation of RNA export from nucleus | biological process | KHDRBS1 |
| regulation of RNA metabolic process | biological process | RASA1, PCBP4, HNRNPA0, NOVA2, HNRNPA1, HNRNPA3, HNRNPD, HNRNPA2B1, PCBP3, PCBP1, TRA2B, RBM3, HNRNPAB, TRA2A, NOL8, RBM28, HNRNPDL, PCBP2, RBM23, SF3B4, RBM24, MSI1, NCL, HNRNPK, RBMXL1, RBM38, NOVA1 |
| regulation of RNA polymerase II regulatory region sequence-specific DNA binding | biological process | LIF, NSD1, ZMPSTE24, ZBTB7C |
| regulation of RNA polymerase II transcription preinitiation complex assembly | biological process | DR1, ATF7IP |
| regulation of RNA splicing | biological process | BRDT, CLK3, RBFOX2, FUS, HNRNPF, SNRNP70, GRSF1, RBM12, HNRNPH3, ESRP1, CLK2, TRA2B, PRX, FASTK, MBNL1, MBNL3, HNRNPH2, AFF2, AHNAK, SON, HNRNPH1, CLK4, CLK1, MBNL2, HNRNPLL, RBM17, RBFOX1, PQBP1, ZNF326, ESRP2, CDK12, PTBP3, MYOD1, RRP1B, AHNAK2, RBM38, RBFOX3, RBM20, RBM12B, METTL4, SRRM4 |
| regulation of rRNA processing | biological process | USP36 |
| regulation of rRNA stability | biological process | DDX49 |
| regulation of ruffle assembly | biological process | ICAM1, CORO1C, RHOG, RCC2, RDX, SH3YL1, P2RX4, CAV1 |
| regulation of ryanodine-sensitive calcium-release channel activity | biological process | CAMK2D, DMD, JPH4, JPH3, SELENON, CALM1, CALM3, JPH2, PLN, FKBP1B, PDE4D, ASPH, HRC, JSRP1, JPH1 |
| regulation of SA node cell action potential | biological process | RYR2, ANK2 |
| regulation of saliva secretion | biological process | OPRK1, FGF10 |
| regulation of sarcomere organization | biological process | MEF2C, AKAP13 |
| regulation of satellite cell activation involved in skeletal muscle regeneration | biological process | GJD4 |
| regulation of Schwann cell differentiation | biological process | CDK1 |
| regulation of secondary heart field cardioblast proliferation | biological process | CTNNB1, ISL1, HES1, HAND2 |
| regulation of secretion | biological process | POFUT2, MYO6 |
| regulation of sensory perception of pain | biological process | IL10, FGFR1, COMT, F2R, OXT, ACPP, SCN11A, CCL3, FABP5, TAFA4, SLC9A1, SMR3B, TAC4, EDNRB, OPRD1, NPFF, TMEM100, NMUR2, EDN1, CCK, ADRA2C, NTSR1, OPRL1, MGLL, GRIN2D, GRM1 |
| regulation of sequence-specific DNA binding transcription factor activity | biological process | HMOX1, MAPK3, MAPK1, MAPK8, MAPK14, FANCA, STK36, C3orf33, MAPK11, FANCD2, SYK, MAPK9, SGK1, USP7, SGK3, CREBZF, ATF2, CARF, FOS, POU4F1, POU4F2, SIX6OS1, HCK, KDM5A, ZBTB7A, MAPK10 |
| regulation of sequestering of calcium ion | biological process | CASQ1, SLC25A23 |
| regulation of sequestering of zinc ion | biological process | AP3D1, SLC30A2, SLC30A8, SLC30A3, SLC30A4 |
| regulation of serotonin secretion | biological process | CRH |
| regulation of serotonin uptake | biological process | ITGB3 |
| regulation of short-term neuronal synaptic plasticity | biological process | SYNGR1, SYP, UNC13B, CLN3, PPFIA3, RAB3GAP1, UNC13A, SLC8A2, SHISA7, GRIK2, SHISA6, SLC4A10 |
| regulation of signal transduction | biological process | GNAS, BIRC5, NODAL, SPRY4, GPC2, SOCS2, TDGF1, ACVR1B, PPP1R2, TSPYL2, NUP62, GPC5, SPRY1, SPRED1, GLRX2, ACVR2B, AFAP1L2, GPC6, NCLN, SLA2, CNKSR2, CDC42SE2, MTCH1, IGBP1, PTPN1, ACVR2A, VEPH1, CNKSR3, SPRY2, YWHAG, GPC4, SLA, GPC1, CRK, FURIN, GPC3, AFAP1, MGLL, UGCG, SPRY3 |
| regulation of signal transduction by p53 class mediator | biological process | TP53, BRCA1, AKT1, MDM2, ATM, MTA2, CSNK2A2, CSNK2B, ATR, TAF4B, TP63, NBN, MAPK14, RPL5, RBBP8, TRIM24, TAF5, TAF12, SUPT16H, RPA2, RFC4, RPL11, RBBP7, ZNF385A, PIN1, MAPK11, HDAC2, TAF9B, PRKAB1, RFC5, RFC3, TP53BP2, TP53INP1, JMY, PRKAG2, RPA1, HIPK1, MAPKAPK5, SETD9, EHMT2, MDM4, HIPK4, RPF2, L3MBTL1, TAF13, TAF7, TOPBP1, EXO1, TAF11, TPX2, RAD17, TAF3, DYRK2, MRE11, RAD9B, EHMT1, TAF15, RAD9A, RAD1, TAF1, CSNK2A1, RBBP4, EP300, CDK5R1, KAT5, HIPK2, BRPF1, CHD4, PHF20, HUS1, TAF2, MEAF6, PML, RPA3, TAF6, TAF4, PRKAA2, TAF10, RAD50, PAK1IP1, RFC2, BLM, POU4F1, RRS1, PPP1R13B, BARD1, MBD3, NOP2, SSRP1, POU4F2, BANP, BRIP1, CDK5, PLK3, KAT6A, TP53RK, CHD3, NOC2L, ATRIP, ING5, AURKB, RHNO1, TAF9, RMI1, SMYD2, NUAK1, PPP1R13L, KMT5A |
| regulation of signal transduction by receptor internalization | biological process | CAV3 |
| regulation of signal transduction involved in mitotic G2 DNA damage checkpoint | biological process | RINT1 |
| regulation of signaling | biological process | CAV3, CBL, CBLB, CBLC, MVP |
| regulation of single stranded viral RNA replication via double stranded DNA intermediate | biological process | CXCL8 |
| regulation of sister chromatid cohesion | biological process | BUB1 |
| regulation of skeletal muscle acetylcholine-gated channel clustering | biological process | FZD9, CRKL |
| regulation of skeletal muscle adaptation | biological process | CAMK2B, CAMK2G |
| regulation of skeletal muscle cell differentiation | biological process | NR1D2, KLHL41, DDX17, SIX1, UQCC2 |
| regulation of skeletal muscle cell proliferation | biological process | SIX1 |
| regulation of skeletal muscle contraction | biological process | DMD, C12orf57, CAV3, SLC8A3 |
| regulation of skeletal muscle contraction by action potential | biological process | SCN4A |
| regulation of skeletal muscle contraction by calcium ion signaling | biological process | DMPK |
| regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion | biological process | DMD, CASQ1 |
| regulation of skeletal muscle contraction via regulation of action potential | biological process | KCNJ2 |
| regulation of skeletal muscle fiber development | biological process | HDAC4, NACA, HDAC9, FBXO22 |
| regulation of skeletal muscle fiber differentiation | biological process | NLN |
| regulation of skeletal muscle satellite cell proliferation | biological process | PPARD, CFLAR, ANGPT1, PAXBP1, SIX1, MYOG |
| regulation of skeletal muscle tissue development | biological process | MEGF10, WNT10B |
| regulation of skeletal muscle tissue growth | biological process | DLL1 |
| regulation of slow-twitch skeletal muscle fiber contraction | biological process | MYH7 |
| regulation of SMAD protein import into nucleus | biological process | TGFB1, OVOL2, SPTBN1, TOB1, WWTR1, GDF5 |
| regulation of small GTPase mediated signal transduction | biological process | A2M, ARHGDIA, CDC42, SOS1, SIPA1L3, ARHGEF3, KALRN, CHN1, SYDE2, RALGAPA1, ARAP1, ARHGAP32, GDI2, ARHGEF7, RHOU, ARHGEF11, SRGAP3, RALBP1, VAV3, OCRL, DLC1, ARHGAP9, SIPA1L2, MCF2, BCR, ABR, ARHGEF6, GARNL3, ARHGAP35, ARHGAP33, ARHGEF9, ARHGEF5, RALGAPB, ARHGAP45, ARHGEF4, RHOD, RHOG, AMOT, ARHGAP22, ARHGAP24, ARAP2, ARHGAP17, ARAP3, ARHGEF12, ARHGAP8, ARHGAP5, RHOF, STARD13, MYO9A, SRGAP2, SOS2, RALGAPA2, RHOQ, CHN2, TIAM1, ARHGAP19, ARHGAP31, RAC1, ARHGAP1, ARHGAP21, ARHGAP18, PLEKHG2, ECT2, RAC2, VAV2, ARHGAP29, OBSCN, RHOT2, DEPDC1B, ARHGEF2, DEPDC7, ARHGAP26, ARHGAP6, FAM13A, AKAP13, RHOT1, TRIO, RHOBTB1, ARHGDIB, INPP5B, TRIP10, TAGAP, ARHGEF1, FGD4, FAM13B, RASGRF2, MCF2L, OPHN1, NGEF, SIPA1, ARHGEF17, ARHGDIG, ARHGAP25, RAP1GAP, RAC3, FGD2, PREX1, ARHGAP4, ARHGAP15, ARHGAP30, RHOJ, TSC2, ARHGAP12, RHOV, PIK3R2, RHOC, VAV1, RHOH, GMIP, PLEKHG5, MYO9B, ARHGEF16, ARHGEF18, RHOBTB2, ARHGAP10, ITSN1, NET1, SRGAP1, ARHGAP39, ARHGAP23, ARHGAP44, RAP1GAP2, TIAM2, ARHGAP11A, ARHGEF26, ARHGAP20, GDI1 |
| regulation of smooth muscle cell apoptotic process | biological process | RBM10, PDE1A |
| regulation of smooth muscle cell differentiation | biological process | FGFR2, BMP4, ZEB1, MYOCD, SRF |
| regulation of smooth muscle cell migration | biological process | ACE, PLAU, PDGFA, PLXNA1, SORL1 |
| regulation of smooth muscle cell proliferation | biological process | CTNNB1, BMP4, TCF7L2, XRCC5, PDE1A, XRCC6, PRKDC, ELN, NPPC, NR4A3 |
| regulation of smooth muscle cell-matrix adhesion | biological process | PLAU |
| regulation of smooth muscle contraction | biological process | FLT1, ADRB2, NMU, ADRA2A, PLCE1, CHRNA3, ATP1A2, CNN1, NMUR2, ADRA2B, ADRA2C, CHRM2, CHRNB4, CAV1 |
| regulation of smoothened signaling pathway | biological process | FGFR2, TULP3, TCTN1, INTU, CREBBP, GAS1, ARL6, RORA, TTC21B, FBXL17, C2CD3, GLI1, FUZ, ACTRT1, PTCH1, IFT172, RPGRIP1L, IFT81, FGF10 |
| regulation of SNARE complex assembly | biological process | VPS41, VPS18, STXBP6, VPS16, SEPTIN8 |
| regulation of sodium ion transmembrane transport | biological process | FGF12, RANGRF, DLG1, SLMAP, SNTA1, BPIFA1, SCN5A |
| regulation of sodium ion transmembrane transporter activity | biological process | FGF12, YWHAH, UTRN, FXYD1, RANGRF, CAV3, FXYD4, SCN1B, FXYD3, GPD1L, FXYD2, FXYD6, SCN4B, PTPN3, SCN2B, FXYD7, SCN3B |
| regulation of sodium ion transport | biological process | TGFB1, NOS3, DMPK, PER1, YWHAH, ADRB2, WNK1, SCN1B, NKAIN2, SLC8A1, NKAIN4, P2RX7, ATP1A1, P2RX4, DRD2, SIK1, SPTBN4 |
| regulation of sodium-dependent phosphate transport | biological process | CRY2 |
| regulation of sodium:proton antiporter activity | biological process | SLC9A3R1 |
| regulation of somatic stem cell population maintenance | biological process | TAF6L, TAF5L |
| regulation of somitogenesis | biological process | DMRT2, NOTCH1, CDX2, CDX1, DLL1, LFNG |
| regulation of spindle assembly | biological process | SENP6 |
| regulation of spongiotrophoblast cell proliferation | biological process | PHLDA2 |
| regulation of spontaneous synaptic transmission | biological process | SLC12A2, AGER |
| regulation of sprouting angiogenesis | biological process | GLUL, PPP1R16B, CEMIP2, FGF18, CEACAM1, RHOJ |
| regulation of stem cell differentiation | biological process | GDNF, NSUN2, KDM4C, OCIAD1, TEAD2 |
| regulation of stem cell division | biological process | NCOA3, CDK2AP2, MLLT3, NAP1L2, EVI2B, SFRP2, PRDM15, ESRRB |
| regulation of stem cell population maintenance | biological process | NODAL, CNOT1, PTN, ZC3H13, HMGA2, SMO, SAV1, CNOT2, KAT2A, CNOT3 |
| regulation of stem cell proliferation | biological process | FGFR1, NF2, SOX18, AGO3, YAP1, ZFP36L1 |
| regulation of steroid biosynthetic process | biological process | NR5A1, LEP, STAR, IGFBP7, DDX20, DHH, SF1 |
| regulation of steroid metabolic process | biological process | STAT5B, RORA, RORC |
| regulation of store-operated calcium channel activity | biological process | PLA2G6 |
| regulation of store-operated calcium entry | biological process | SPINK1, SARAF, JPH4, HOMER2, EFHB, STC2, GRAMD2A, HOMER1, CD84, CASQ1, SLC8B1, HOMER3, STIM1 |
| regulation of stress fiber assembly | biological process | PIK3R1, ROCK2, TSC1, MKKS, SYNPO, SLC9A1, BBS4, ROCK1, RAC1, ALMS1, ACTG1, PTGER4, ASAP3, WAS, FHOD1, MYOC |
| regulation of stress granule assembly | biological process | PRKAA2 |
| regulation of stress-activated MAPK cascade | biological process | MAPK3, MAPK1, GSTP1, PRDX1, NBR1, MAP2K2, MAP2K1, PAGE4, GREM1 |
| regulation of stress-activated protein kinase signaling cascade | biological process | ZMPSTE24 |
| regulation of striated muscle cell differentiation | biological process | HDAC4, HDAC9 |
| regulation of striated muscle contraction | biological process | SRI, MYBPC3, ATP1A2, MYL2, ATP2A1, MYL3, TNNT3, TNNI1, MYBPH |
| regulation of striated muscle tissue development | biological process | TGFB1, CENPF, LOX, SMAD3 |
| regulation of substrate adhesion-dependent cell spreading | biological process | CORO1C, PTK2, PDPN, WASHC2C |
| regulation of succinate dehydrogenase activity | biological process | SIRT5 |
| regulation of superoxide anion generation | biological process | SYK |
| regulation of superoxide dismutase activity | biological process | SZT2 |
| regulation of superoxide metabolic process | biological process | SHC1, BST1 |
| regulation of supramolecular fiber organization | biological process | PARK7 |
| regulation of synapse assembly | biological process | GRIN1, EPHB2, GHSR, NTN1, MEF2C, SETD5, PDLIM5, PPP1R9A, NECTIN1, RAB17, CHRNB2 |
| regulation of synapse maturation | biological process | DISC1, YWHAZ, CLSTN1 |
| regulation of synapse organization | biological process | ETV5, ARF4, GPM6A, IL10RA, WNT3A, CTTNBP2, IGSF9, SLITRK4, DKK1, NEDD4, KLK8, SLITRK1, TUBB, SEPTIN11, PTPRO, CDH8, DAG1, SLITRK2, CAMK1, TNF |
| regulation of synapse structural plasticity | biological process | DMPK, CAMK2B, CTNNA2, PPP1R9A, DRD2 |
| regulation of synapse structure or activity | biological process | APP, PPT1, DNM3, MX1, SLC17A6, MX2, DNM1, SLC17A7 |
| regulation of synaptic activity | biological process | MEF2C, STX1B |
| regulation of synaptic growth at neuromuscular junction | biological process | SIX1, SIX4, AGRN |
| regulation of synaptic membrane adhesion | biological process | MDGA1, LRFN3, PCDH8 |
| regulation of synaptic plasticity | biological process | NCAM1, CNTN4, PLK2, RIMS2, BAIAP2, YWHAH, GRIN1, RAPGEF2, PTN, RIMS1, GIPC1, HRH1, EIF4EBP2, JPH4, PPP3CB, JPH3, CALB1, MEF2C, ATF4, PSEN1, MECP2, GRIN2C, CX3CR1, CPEB3, GRIN2B, NFATC4, YWHAG, ADGRB1, SCT, CDK5, KAT2A, VGF, ITPKA, SCTR, GRIN2A, RIMS3, LZTS1, HRH2, INS, P2RX3, NPAS4, RASGRF1, BRSK1, GRIN2D, PTK2B, FGF14, RIMS4, RARA, AGER |
| regulation of synaptic plasticity by receptor localization to synapse | biological process | ANKS1B |
| regulation of synaptic transmission, dopaminergic | biological process | PNKD, CHRNB2, CNTNAP4 |
| regulation of synaptic transmission, GABAergic | biological process | PTEN, KRAS, PLCL1, CNR1, CLN3, NISCH, DRD2, NPAS4, SYN3, BAIAP3, NF1, PLCL2, CNTNAP4 |
| regulation of synaptic transmission, glutamatergic | biological process | GRM3, GRM4, TPRG1L, GRM8, DISC1, SYT1, DGKI, MEF2C, DKK1, PSEN1, UCN, DGKZ, CNR1, ATP1A2, HOMER1, CLN3, GRM2, OPHN1, GRM6, CDK5, MAPK8IP2, UNC13A, GRIK1, GRM5, GRM7, LRRK2, TNF, GRM1 |
| regulation of synaptic vesicle budding from presynaptic endocytic zone membrane | biological process | SLC2A4 |
| regulation of synaptic vesicle clustering | biological process | PCDH17, BRSK1 |
| regulation of synaptic vesicle cycle | biological process | PLD1, SYN1, RAB3B, BSN, CDK5R1, DNAJC5, PRKAR1B, RAPGEF4 |
| regulation of synaptic vesicle endocytosis | biological process | PPP3CB, PPP3CC, ROCK1, VAMP4, CALM3, DNM1, SYT7, DGKQ, BTBD9, SH3GL1, LRRK2, SLC17A7 |
| regulation of synaptic vesicle exocytosis | biological process | P2RY4, CHRNA5, RIMS2, VPS18, RIMS1, DVL1, GIPC1, SNAPIN, PPFIA2, PFN2, RAB5A, SYT1, DGKI, SYP, GIT1, SYN1, DTNBP1, ADRA1A, PRKCB, CALM3, NCS1, PREPL, APBA2, APBA1, P2RY1, CHRNA6, GRIN3A, CASK, DRD1, HTR1B, SEPTIN5, BACE1, RIMS3, CSPG5, CHRNB2, ADORA2B, CHRNA4, PRKCG, DRD2, ADORA2A, WNT7A, CHRM2, STXBP5L, LRRK2, FBXL20, RIMS4 |
| regulation of synaptic vesicle fusion to presynaptic active zone membrane | biological process | CPLX1, VAMP1, GRIK5, CPLX2, CPLX3 |
| regulation of synaptic vesicle priming | biological process | STX1B, NAPA, NAPB |
| regulation of synaptic vesicle recycling | biological process | SNCA, CDK5, FGF14 |
| regulation of synaptic vesicle transport | biological process | PRKN, PINK1, LRRK2 |
| regulation of systemic arterial blood pressure | biological process | DDAH1, PLCB3, POSTN, KLK2, GJA5, KLK1, NCALD, KCNK6 |
| regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback | biological process | ASIC2 |
| regulation of systemic arterial blood pressure by atrial natriuretic peptide | biological process | RASL10B |
| regulation of systemic arterial blood pressure by baroreceptor feedback | biological process | NAV2 |
| regulation of systemic arterial blood pressure by endothelin | biological process | NOS3, ECE1, EDN1, EDN3 |
| regulation of systemic arterial blood pressure by norepinephrine-epinephrine | biological process | ADRB2 |
| regulation of systemic arterial blood pressure by renin-angiotensin | biological process | ACE, ACE2, NOX1, AGTR1, ENPEP, AGT |
| regulation of systemic arterial blood pressure by vasopressin | biological process | OXTR, AVPR2, AVPR1B |
| regulation of systemic arterial blood pressure mediated by a chemical signal | biological process | SLC2A5 |
| regulation of T cell activation | biological process | CCL5, IL20RB, RC3H1, CGAS, CRTAM, CD4, PAG1, SPN, KAT2A, LAT, TREX1, SIT1 |
| regulation of T cell anergy | biological process | HLA-B, PHLPP1 |
| regulation of T cell antigen processing and presentation | biological process | WAS |
| regulation of T cell chemotaxis | biological process | CXCL10 |
| regulation of T cell cytokine production | biological process | TRPM4 |
| regulation of T cell differentiation | biological process | RAG1, CYP26B1, IL15, PRELID1, SPINK5, HLA-DOA, ABL1, ADA, CD2, CRTAM, TBX21, CARD11, SLC46A2 |
| regulation of T cell differentiation in thymus | biological process | SOD1, SOS1, CAMK4, FOXN1, CLPTM1, ZEB1 |
| regulation of T cell homeostatic proliferation | biological process | IL2RA, IL2, LMO1 |
| regulation of T cell mediated cytotoxicity | biological process | RIPK3, AGER |
| regulation of T cell mediated immune response to tumor cell | biological process | HMGB1 |
| regulation of T cell migration | biological process | ECM1, CCR6, SPN, CRK, CRKL |
| regulation of T cell proliferation | biological process | CTNNB1, SOS1, CTLA4, CD209, IL27, RC3H1, RAC2, CD28, TNFSF8, TNFSF9 |
| regulation of T cell receptor signaling pathway | biological process | MALT1, BCL10, PTPN22, RC3H1 |
| regulation of T cell tolerance induction | biological process | IL2RA |
| regulation of T-helper 1 cell differentiation | biological process | IL27 |
| regulation of tau-protein kinase activity | biological process | APOE, HGF, C5AR1 |
| regulation of telomerase activity | biological process | ATM, SMG6, HMBOX1, NABP2, PARP4, PINX1 |
| regulation of telomerase RNA localization to Cajal body | biological process | DKC1, PARN, DCP2 |
| regulation of telomere capping | biological process | USP7 |
| regulation of telomere maintenance | biological process | MYC, TERF2IP, XRCC5, HNRNPD, UPF1, HDAC8, SMG6, SMG1, SMG5 |
| regulation of telomere maintenance via telomerase | biological process | TNKS, POT1, SMG7, SMG6, SMG5 |
| regulation of telomere maintenance via telomere lengthening | biological process | TINF2 |
| regulation of terminal button organization | biological process | VPS35 |
| regulation of termination of RNA polymerase I transcription | biological process | ZMPSTE24 |
| regulation of testosterone biosynthetic process | biological process | AKR1C3 |
| regulation of thalamus size | biological process | SLC6A4 |
| regulation of the force of heart contraction | biological process | IFNG, MYH7, ADM, GAA, ATP2A2, CAMK2D, MYL4, SLC9A1, GLRX3, GRK2, ATP1A2, PLN, CSRP3, SLC8A1, ATP1A1, MYL2, MYL3, MYH6, CAV1 |
| regulation of the force of heart contraction by cardiac conduction | biological process | SLC9A1, PLN |
| regulation of the force of heart contraction by chemical signal | biological process | NOS3, CAV1 |
| regulation of the force of skeletal muscle contraction | biological process | MYH7, ACTN3 |
| regulation of thymocyte apoptotic process | biological process | HIF1A, TP53 |
| regulation of thymocyte migration | biological process | AIRE |
| regulation of thyroid hormone generation | biological process | DUOXA2, DUOXA1 |
| regulation of thyroid hormone mediated signaling pathway | biological process | PRCP, NCOA1, THRA |
| regulation of thyroid-stimulating hormone secretion | biological process | PAX8 |
| regulation of timing of anagen | biological process | SPINK5 |
| regulation of timing of catagen | biological process | TGFB2 |
| regulation of timing of cell differentiation | biological process | FGF9, HES1, GDPD5, RBPJ |
| regulation of timing of neuron differentiation | biological process | HES1 |
| regulation of timing of subpallium neuron differentiation | biological process | ASCL1 |
| regulation of tissue remodeling | biological process | GPNMB, THBS4, TP53, HAND2 |
| regulation of tolerance induction | biological process | MARCHF7, HMGB1 |
| regulation of tolerance induction dependent upon immune response | biological process | HAVCR2 |
| regulation of Toll signaling pathway | biological process | PELI1, PELI2, PELI3 |
| regulation of toll-like receptor 9 signaling pathway | biological process | TLR9 |
| regulation of toll-like receptor signaling pathway | biological process | BIRC2, MFHAS1, GFI1, ESR1, CD36 |
| regulation of TOR signaling | biological process | LAMTOR3, ZMPSTE24, TBCK, FBXO9, FAM83D, ROS1, RRAGB, TMEM127, TTI1, GNA12, RHEB, FLCN, ITFG2, TREM2, GPAT3, PKHD1 |
| regulation of TORC1 signaling | biological process | DYRK3, C9orf72, SMCR8, DGKQ |
| regulation of TRAIL receptor biosynthetic process | biological process | PARK7 |
| regulation of transcription by RNA polymerase I | biological process | POLR2L, POLR2K |
| regulation of transcription elongation from RNA polymerase II promoter | biological process | SUPT4H1, ZMYND11, LDB1 |
| regulation of transcription from RNA polymerase II promoter | biological process | INHBA, VEGFA, ATF3, WT1, BRD2, AHR, BRCA1, SOX9, NRIP1, SOX10, NR5A1, SOD2, SP1, HNF1A, STAT1, HSF2, EZH2, BRWD1, CHD2, CTNNB1, STAT3, IFNAR2, RB1, ESX1, THRB, NR2F2, OTX1, PPARG, FOXO1, TAF7L, CLOCK, USF1, ECM1, TCF7L2, MYCN, ANXA4, MAPK14, ETV2, MED7, TADA3, HMGN1, GLI3, H1-4, PAM, CCNC, RBL1, FUS, TCF7, IRX6, MLLT1, RBL2, CAMK2D, TFDP1, ELOC, ZMYM1, ATAD2, NFXL1, ZFPM2, RBBP8, MED4, ZMYM2, KDM5B, KLF4, TRAK2, PIAS1, NPM1, HOXA6, DDIT3, SMARCA2, CEBPG, MAX, CREB5, GLO1, KLF9, ELF2, QRICH1, LRRFIP1, ZBED5, EPC2, SRCAP, MED8, ZNF700, ENY2, BAZ2B, OGT, TBX10, ZIC2, ACTL6A, SPI1, PBX2, RFX5, IRX1, NHLH1, ELP2, THAP6, WDR77, RCOR3, HIF3A, USP16, HCFC2, SMARCA5, CIAO1, ATF1, BCL6, RFX3, SMARCA4, CCNH, TFCP2, SMAD4, HNF4G, ZBTB6, UTF1, BHLHE22, SNIP1, NEUROG2, BRD9, TCF7L1, MRGBP, SLTM, STOX2, RERE, RNF14, MAGED1, HTATSF1, CCNT1, PIAS2, EOMES, TGFA, ZNF14, DEK, STAT5B, SUB1, PPARD, ZBTB10, LCOR, IRF2BPL, UBP1, BAZ1B, FOXN3, SAP18, HMGB3, TSC22D2, SUPT3H, PSMD10, LYL1, ELF1, PSMC5, SP4, PRDM2, ZMYM3, HES1, TSC22D1, |
| regulation of transcription from RNA polymerase II promoter by glucose | biological process | USF1, USF2 |
| regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance | biological process | ATF3 |
| regulation of transcription from RNA polymerase II promoter in response to DNA damage | biological process | TP53 |
| regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | VEGFA, HIF1A, PSMB1, PSMB5, PSMC2, ELOC, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, HIGD1A, PSMD6, PSMD1, HIF3A, PSMD14, PSMD7, PSMB6, RPS27A, PSMD10, PSMD8, PSMC5, EGR1, PSMB4, PSME1, CREBBP, BACH1, PSMB8, PSMD4, PSMC3, PSMA6, CA9, STOX1, EP300, ELOB, PSMD12, PSMB9, PSMC4, CUL2, PSMD9, PSMA4, PSMD2, UBC, UBA52, PSMD5, PSMF1, EPAS1, EGLN1, PSMB3, HIF1AN, PSMD3, PSMC1, RBX1, EGLN2, LIMD1, VHL, UBB, EPO, PSMD13, PSMB10 |
| regulation of transcription from RNA polymerase II promoter in response to iron | biological process | HMOX1, SLC40A1 |
| regulation of transcription from RNA polymerase II promoter in response to oxidative stress | biological process | HIF1A, HMOX1, SIN3A, ANKRD2, EPAS1 |
| regulation of transcription from RNA polymerase II promoter in response to stress | biological process | MUC1, DDIT3, HSF5, HSFX1, HSFY1, INO80, HSF4 |
| regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment | biological process | DLX1, DLX2 |
| regulation of transcription from RNA polymerase II promoter involved in kidney development | biological process | GLIS2 |
| regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation | biological process | NOTCH1, RBPJ, TBX2 |
| regulation of transcription from RNA polymerase II promoter involved in spermatogenesis | biological process | DHX36 |
| regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification | biological process | LBX1 |
| regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification | biological process | EVX1 |
| regulation of transcription from RNA polymerase III promoter | biological process | BRCA1, POLR3F, DHX36, ZNF143, POLR3C, BRF2, ZNF76, ZNF345 |
| regulation of transcription involved in anterior/posterior axis specification | biological process | DDIT3 |
| regulation of transcription involved in cell fate commitment | biological process | PPARG, RORA, CHD5, RORC, ZBTB7B |
| regulation of transcription involved in G1/S transition of mitotic cell cycle | biological process | CDK1, RB1, PCNA, BRD4, CCNA1, TFDP1, TYMS, E2F4, CDK14, RRM2, NPAT, CDK15, BACH1, ORC1, CDC45, CDC6, CCNE1, KLF11, DHFR, E2F6, CDK18, TFDP2, CDK5, CDK17, HINFP, GFI1, POLA1 |
| regulation of transcription involved in G2/M transition of mitotic cell cycle | biological process | BACH1 |
| regulation of transcription involved in lymphatic endothelial cell fate commitment | biological process | NR2F2, PROX1 |
| regulation of transcription of nucleolar large rRNA by RNA polymerase I | biological process | SIRT7 |
| regulation of transcription regulatory region DNA binding | biological process | DOT1L, ZBTB7A |
| regulation of transcription, DNA-templated | biological process | NR5A2, IFNG, ESR1, TP53, PGR, AR, VDR, ATF3, WT1, BRD2, AHR, BRCA1, SOX9, NRIP1, SOX10, NR5A1, HIF1A, ESR2, BIRC5, OGG1, ZEB2, NR1I2, IGF2, ERBB2, SP1, ERCC2, HNF1A, DNMT1, MAPK1, HNF1B, SOX3, STAT1, FASLG, NR0B1, HSF1, E2F1, HSF2, SRY, KANK1, STAT4, EZH2, NFE2L2, BRDT, CDKN2A, CTCFL, MBD3L1, PEG3, ARNT2, BRWD1, MBD2, MBD1, PLAGL1, DMRT1, CHD2, MTA2, NR3C1, ENO1, PARP1, FGFR1, CSNK2A2, CTNNB1, STAT3, LBX2, IGSF1, DMRT2, ZFP37, KAT7, LTF, INSR, RB1, C1QBP, KHDRBS1, NCOA2, SOHLH1, LIN28B, ESX1, EBF2, PROP1, THRB, MAK, NR2F2, APEX1, OTX1, PPARG, GATA4, SOX2, CDK9, SUMO1, MEF2A, EMX1, FOXO1, SHH, TAF7L, STRA8, HSFY1, ZNF331, CHD7, CLOCK, BRD4, USF1, SOX5, ETV5, KDM5C, CREM, NR1H3, TAF4B, DPF3, TADA1, GMCL1, PRMT6, SIN3A, TSC22D3, NPAS2, RHOXF2, ZMYND15, TP63, TCF7L2, PRDM9, SOHLH2, GTF2A1L, WASL, MYC, MYCN, YLPM1, TBPL1, DYNLL1, FOXM1, ZNF174, MAPK14, TGIF2LY, TGIF2LX, PATZ1, ZNF230, YBX2, ETV2, ZNF646, SHOX, HOXA3, ZRANB2, GLI3, H1-4, HOXD13, FUS, TCF7, HINT1, SUPT4H1, IRX6, EWSR1, RPL6, MLLT1, GTF2H3, TFDP1, NR |
| regulation of transepithelial transport | biological process | ACTG1 |
| regulation of transforming growth factor beta activation | biological process | LTBP1, ITGB6, LRRC32, ITGB8 |
| regulation of transforming growth factor beta receptor signaling pathway | biological process | TGFB1, SMAD4, BCL9, CAV3, SOX11, LOX, ZEB1, SMAD2, NREP, TRIM33, ZNF703, DAND5, IL17F, SMURF2, ENG, ITGA3, LTBP4, SMAD3, FOLR1 |
| regulation of transforming growth factor beta2 production | biological process | HIF1A, SMAD4, TGFB2, SMAD3 |
| regulation of transforming growth factor beta3 activation | biological process | LRRC32 |
| regulation of translation | biological process | AKT1, GAPDH, APP, PIWIL2, DAZL, PIWIL1, IGF1, NANOS2, PUM2, NANOS1, DDX25, PIWIL4, BOLL, S100A9, NANOS3, PIWIL3, MATR3, RPS14, PAIP1, DDX3X, TYMS, NCBP2, EIF4G2, PUM1, IGF2BP2, CNOT1, AIRE, FXR1, SARNP, PTCD3, ZNF385A, KLHL25, DHX36, AGO4, CNOT8, EPRS1, LSM14A, EIF2A, SYNCRIP, NCK1, RPS6KB1, RPL38, RACK1, EIF2AK1, NEURL1, RPS3, RPL13A, EIF4EBP2, DNAJC1, RBM4B, TACO1, CASC3, RPLP1, IREB2, RBM3, NCBP1, MAPKAPK5, TSC1, TARBP2, GCN1, AGO3, NCK2, UNK, CNOT10, MKNK2, PYM1, NIBAN1, RBM8A, EIF4EBP1, CPEB4, GEMIN5, POLDIP3, EIF4E, MRPS27, CNOT9, CPEB1, SAMD4A, EIF4E2, RGS2, FXR2, CTIF, EIF2S1, RPL10, LARP6, CYFIP1, CPEB2, LSM14B, AGO2, DNAJC3, LARP1, EIF4E3, CPEB3, HNRNPLL, CNOT6L, QKI, CNOT2, TNRC6B, PPP1R15A, ZFP36L1, HABP4, TNRC6A, NGDN, TNRC6C, DAPK1, TCOF1, RBM24, AGO1, MIF4GD, IGF2BP3, PTBP3, KBTBD8, MKNK1, CNOT3, ACO1, ALKBH1, ZNF706, FOXO3, PUM3, IMPACT, PKP3, AKT2, RBM20, EIF4A3, MTG1, IGF2BP1, GRM5, ZNF598, LARP4B, METAP1, ATXN2, EIF2AK3, EIF2B4, PCIF1 |
| regulation of translation at postsynapse, modulating synaptic transmission | biological process | EIF4E, CYFIP1, EIF4A3 |
| regulation of translation by machinery localization | biological process | PADI6 |
| regulation of translation in response to stress | biological process | RPS6KA1 |
| regulation of translation involved in cellular response to UV | biological process | RPL26 |
| regulation of translational elongation | biological process | ALKBH1, GRM5 |
| regulation of translational fidelity | biological process | YRDC, HSPA14, RPS5, AARSD1, GATC |
| regulation of translational initiation | biological process | HSPB1, EIF3H, EIF3E, DDX1, PAIP1, NCBP2, EIF4G2, EIF3K, EIF4A2, KLHL25, EIF1, EIF2B1, NCBP1, EIF3B, EIF5, EIF5B, EIF4B, GLE1, CTIF, EIF1B, EIF2B2, MIF4GD, ALKBH1, IMPACT, EIF4H |
| regulation of translational initiation by eIF2 alpha dephosphorylation | biological process | PPP1R15A |
| regulation of translational initiation by eIF2 alpha phosphorylation | biological process | EIF2AK1, EIF2AK2, EIF2AK3 |
| regulation of translational initiation in response to stress | biological process | EIF2S1 |
| regulation of translational termination | biological process | GSPT1, ETF1, MTRF1, UPF1, GLE1, SHFL, OGFOD1 |
| regulation of transmembrane transporter activity | biological process | BCL2, SNCA, INS |
| regulation of transmission of nerve impulse | biological process | GHSR, TYMP, AGT |
| regulation of transport | biological process | ICA1 |
| regulation of triglyceride biosynthetic process | biological process | C3 |
| regulation of triglyceride metabolic process | biological process | PANK2, GNB3, SERPINA12, LMF1 |
| regulation of tube size | biological process | WNT9B |
| regulation of tubulin deacetylation | biological process | TADA3, NEK3, EP300 |
| regulation of tumor necrosis factor biosynthetic process | biological process | CX3CR1, CARD9 |
| regulation of tumor necrosis factor production | biological process | LTF, CD47, FOXP1, TBC1D23, ANGPT1, ZFP36, TREX1 |
| regulation of tumor necrosis factor-mediated signaling pathway | biological process | TNF, TNFRSF1A, CASP8, SPPL2A, RACK1, SYK, HIPK1, OTULIN, TAX1BP1, SPPL2B, BIRC2, IKBKG, SHARPIN, CYLD, RBCK1, IKBKB, TRADD, MADD, PYCARD, TRAF1, RNF31, TRAF2, CLIP3 |
| regulation of type 2 immune response | biological process | ECM1 |
| regulation of type B pancreatic cell development | biological process | CLOCK, RHEB, ARNTL |
| regulation of type B pancreatic cell proliferation | biological process | ERRFI1, SGPP2, MEN1, NR1D1, FMC1, NR4A3, NR4A1 |
| regulation of type I interferon production | biological process | TBK1, RNF26, TRIM32, ZBP1, STING1, CGAS, IRF7, TRIM21, IRF3, TREX1, DTX4, NLRP4, TRIM56, POLA1 |
| regulation of type I interferon-mediated signaling pathway | biological process | IFNA1, TYK2, STAT1, IFNAR2, PTPN11, PTPN6, RNASEL, PTPN1, USP18, CDC37 |
| regulation of type III interferon production | biological process | IFIH1 |
| regulation of type IV hypersensitivity | biological process | FUT7 |
| regulation of tyrosine phosphorylation of STAT protein | biological process | IL22RA2, SOCS1, IL23R |
| regulation of tyrosine phosphorylation of Stat1 protein | biological process | IL23A |
| regulation of ubiquinone biosynthetic process | biological process | COQ3, PPTC7 |
| regulation of ubiquitin-dependent protein catabolic process | biological process | UBE3A, NUB1, LATS1, PTK2B |
| regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | biological process | CDK1, CCNB1, CDC20 |
| regulation of ubiquitin-protein transferase activity | biological process | FEM1B, BAG5, FEM1A |
| regulation of ubiquitin-specific protease activity | biological process | ATP13A2 |
| regulation of urea metabolic process | biological process | NR1H4 |
| regulation of urine volume | biological process | AKR1B1 |
| regulation of uterine smooth muscle contraction | biological process | SETD3, TACR2 |
| regulation of vacuole fusion, non-autophagic | biological process | ENO2, ENO3, VPS16 |
| regulation of vacuole organization | biological process | MTM1 |
| regulation of vascular endothelial growth factor production | biological process | IL6, NDRG2 |
| regulation of vascular endothelial growth factor receptor signaling pathway | biological process | FZD4, TMEM204, VEGFC, MYOF |
| regulation of vascular endothelial growth factor signaling pathway | biological process | CD63, PTP4A3, DLL1 |
| regulation of vascular permeability | biological process | YES1, SRC, BDKRB2, HRH1, BCR, ABR, TEK, GPR4, NPR1, CDH5, AZU1 |
| regulation of vascular permeability involved in acute inflammatory response | biological process | CTNNBIP1, C2CD4B, MYLK3 |
| regulation of vascular smooth muscle cell dedifferentiation | biological process | OLFM2 |
| regulation of vascular smooth muscle contraction | biological process | CHRM3, ADRA2B, ATP2B1 |
| regulation of vasculogenesis | biological process | EMP2, HEY2, HEY1 |
| regulation of vasoconstriction | biological process | ACE, ACE2, ASIC2, BDKRB2, ECE1, PER2, AGTR1, ADRA2A, CHRM3, ADRA1A, ATP1A2, ADRA2B, EDN1, ADRA1B, ADRA2C, TBXA2R, AGT, EDN3, KCNMB4 |
| regulation of vasodilation | biological process | ACE, ACE2 |
| regulation of ventricular cardiac muscle cell action potential | biological process | CTNNA3, RYR2, CACNA1C, DSP, DLG1, PKP2, DSG2, DSC2, JUP, TRPM4, CAV1 |
| regulation of ventricular cardiac muscle cell membrane depolarization | biological process | GJA1, CAV3, GPD1L, GJA5, SCN5A, SCN3B |
| regulation of ventricular cardiac muscle cell membrane repolarization | biological process | CACNA2D1, GJA1, ZMPSTE24, NOS1AP, WDR1, KCNH2, CAV3, SCN1B, ANK2, AKAP9, KCNE4, GJA5, KCNE1, SNTA1, SCN4B, SCN5A, KCNE3 |
| regulation of vesicle fusion | biological process | CPLANE2 |
| regulation of vesicle size | biological process | WASHC5, PICALM, RAB22A, AP2M1, RAB3B |
| regulation of vesicle targeting, to, from or within Golgi | biological process | GOSR1 |
| regulation of vesicle-mediated transport | biological process | RAB11A, RAB25, MBTPS1, SLC30A8, NRP1, FES, USP6 |
| regulation of viral budding via host ESCRT complex | biological process | SNF8 |
| regulation of viral entry into host cell | biological process | TRIM25, TRIM58, TRIM38, TRIM62, TRIM21, TRIM6, TRIM5, TRIM22 |
| regulation of viral genome replication | biological process | BCL2, PPIA |
| regulation of viral life cycle | biological process | LAMP3 |
| regulation of viral process | biological process | CHMP2A, CXCR4, VPS4B, CHMP4B, CHMP4C, CHMP3 |
| regulation of viral transcription | biological process | TARBP2 |
| regulation of vitamin D receptor signaling pathway | biological process | TRIM24, SNW1 |
| regulation of vitamin metabolic process | biological process | CD320 |
| regulation of voltage-gated calcium channel activity | biological process | DMD, HPCA, AHNAK, CACNB4, CACNB1, CACNB3, CACNB2 |
| regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | biological process | DLG1 |
| regulation of voltage-gated sodium channel activity | biological process | FGF12, SCN1B, SLMAP |
| regulation of water loss via skin | biological process | GBA, SRF, ACER1 |
| regulation of Wnt signaling pathway | biological process | HNF1B, SNX3, SENP2, PPP2CA, TCF7L1, CBFB, GSKIP, RUNX1, DCDC2, DKK1, AXIN1, VANGL2, MDFIC, LEF1, RSPO3, SFRP2, AXIN2, PLPP3, SFRP5, ITGA3, PPP2R1A, TMEM237, ESR1 |
| regulation of Wnt signaling pathway, planar cell polarity pathway | biological process | NPHP3, DACT1, ZNRF3 |
| regulation of wound healing | biological process | PLAU, SRSF6, TNFRSF12A, CRK, VIL1 |
| regulation of zinc ion transport | biological process | SLC30A10 |
| regulatory T cell differentiation | biological process | TGFB1, CD28 |
| relaxation of cardiac muscle | biological process | ATP2A2, CAMK2D, RGS2, ATP1A2, PLN, SLC8A1, ATP1B1, KCNJ2, PDE5A, ATP1A1, P2RX4 |
| relaxation of muscle | biological process | P2RY1 |
| relaxation of skeletal muscle | biological process | KCNJ2, ATP2A1 |
| relaxation of smooth muscle | biological process | SLC8A1 |
| relaxation of vascular smooth muscle | biological process | SOD1, GUCY1A1, RGS2, PRKG1, ADORA2B, KCNMA1 |
| release from viral latency | biological process | CREB3, HCFC1 |
| release of cytochrome c from mitochondria | biological process | BCL2, BAX, BAK1, SOD2, CLU, BAD, DNM1L, FZD9, MFF, IFI6, GGCT, BID, TIMM50, FIS1, SFN, BOK, BCL2L1, CCK, BBC3, TP53 |
| release of matrix enzymes from mitochondria | biological process | BAX |
| release of sequestered calcium ion into cytosol | biological process | F2R, PLCH2, DDIT3, XCR1, RYR1, RYR2, CHERP, TMEM38B, PLCL1, PLCB2, PLCB3, PKD2, ERO1A, TRPA1, PLCD1, ITPR3, PTPRC, PLCE1, FKBP1B, IBTK, ITPR1, MCOLN3, TPCN2, P2RX7, CCL19, HTR2C, ITPR2, CCR7, LCK, FGF2, DRD2, RASA3, MCOLN1, TRPM2, PLCD4, PLCG2, PLCH1, MCOLN2, TPCN1, PLCL2, CCL21, HTR2B, TRPV1 |
| release of sequestered calcium ion into cytosol by endoplasmic reticulum | biological process | TMEM38B |
| release of sequestered calcium ion into cytosol by sarcoplasmic reticulum | biological process | CCR5, CCL3, TRDN, RYR1, RYR2, TMEM38B, NOL3 |
| removal of superoxide radicals | biological process | SOD1, NOS3, SOD2, PRDX2, PRDX1, NQO1, ATP7A, FANCC, MT3, MPO, SOD3 |
| renal absorption | biological process | AKR1C3, SLC9A3R1, SLC15A2, HBB, CLDN4 |
| renal artery morphogenesis | biological process | PKD2, NRP1 |
| renal filtration | biological process | ITGA3 |
| renal glucose absorption | biological process | HNF1A |
| renal inner medulla development | biological process | CTNNB1, WNT7B |
| renal interstitial fibroblast development | biological process | HES1 |
| renal outer medulla development | biological process | CTNNB1, WNT7B |
| renal phosphate ion absorption | biological process | SLC9A3R1 |
| renal potassium excretion | biological process | MLLT6, CLN3 |
| renal sodium excretion | biological process | ATP6V1B1, MLLT6 |
| renal sodium ion absorption | biological process | WNK4, MAGED2, SGK1 |
| renal sodium ion transport | biological process | ATP6V1B1, SLC9A3R1 |
| renal system development | biological process | CTNNB1, BMP4, ITGA6, SHH, PKD1 |
| renal system process | biological process | BCL2, FAS, BMP4, RRM2B, BCR, LGMN, MLLT6, PKN1, AGT |
| renal system process involved in regulation of systemic arterial blood pressure | biological process | GJA5 |
| renal tubule development | biological process | STAT1 |
| renal tubule morphogenesis | biological process | COL4A1, MEF2C, PKD2, MTSS1 |
| renal vesicle formation | biological process | CTNNB1, WNT4 |
| renal vesicle induction | biological process | SOX9, WNT4 |
| renal vesicle morphogenesis | biological process | LHX1 |
| renal water absorption | biological process | HAS2, AQP3, HYAL2 |
| renal water homeostasis | biological process | GNAS, ADCY2, CYP11B2, WFS1, AKR1B1, ATP6V1B1, AQP2, RAB11FIP2, RAB11A, PRKAR2A, CYP4A11, PRKACB, ADCY6, ADCY8, AQP3, ADCY7, PRKACG, MYO5B, ADCY9, CYP4F12, AQP1, AVPR2, AVP, PRKAR2B, ADCY4, AKAP11, PRKAR1B, CYP4F2, ADCY5 |
| renal water transport | biological process | AQP2, AQP1 |
| renin secretion into blood stream | biological process | SUCNR1 |
| renin-angiotensin regulation of aldosterone production | biological process | AGTR1, AGT |
| replication fork arrest | biological process | TIPIN, SLFN11, TIMELESS |
| replication fork processing | biological process | PCNA, CDK9, THOC1, ATRX, RFWD3, RTEL1, ALYREF, SMARCAL1, ZRANB3, CENPX, GEN1, FBH1, EXD2, BLM, MMS22L, BOD1L1, ETAA1, DDX11, CENPS, TONSL, EME2, PRIMPOL |
| replication fork protection | biological process | BRCA2, TIPIN, ZNF830, TIMELESS, SMARCAL1, ZRANB3, FBH1, BLM, DONSON |
| replication-born double-strand break repair via sister chromatid exchange | biological process | RECQL5, NIPBL |
| replicative cell aging | biological process | ERCC1, TP63 |
| replicative senescence | biological process | TP53, TERT, CDKN2A, ATM, ATR, PLA2R1, CDKN1A, MME, WNT16 |
| reproduction | biological process | MMP23B, LIN9 |
| reproductive process | biological process | NR5A1, ANTXR1, ANTXR2, PCSK4, LRRC52, NPPC, NPR2, SPTBN4 |
| reproductive structure development | biological process | FKBP4, FGFR2, DLG1, GDF7, RARG |
| reproductive system development | biological process | SPATA22, LRRC6, NDUFS6, PPP1R9B, UBE2Q1, PLEKHA5 |
| rescue of stalled ribosome | biological process | LTN1, RACK1, NEMF, ZNF598, GTPBP2 |
| resolution of meiotic recombination intermediates | biological process | MLH1, TEX11, TOP2A, MEIOB, SLX4, MUS81, CENPX, SHOC1, TOP2B, ERCC4, CENPS, EME2, RMI1 |
| resolution of mitotic recombination intermediates | biological process | GEN1, XRCC3 |
| resolution of recombination intermediates | biological process | GEN1 |
| respiratory basal cell differentiation | biological process | FOXA1 |
| respiratory burst | biological process | CD52, PGAM1, NOX1, CD55, CYBB, CYBA, NCF1, SLC11A1, NCF4 |
| respiratory burst after phagocytosis | biological process | HCK |
| respiratory burst involved in defense response | biological process | PIK3CG, MPO, PIK3CD |
| respiratory chain complex IV assembly | biological process | COA6, COX10, MT-CO3, SCO1, COX18, SURF1, SCO2 |
| respiratory electron transport chain | biological process | MT-CO3, MT-CYB, SDHB, SDHA, ETFRF1, NDUFS6, NDUFAF2, ETFDH, PPARGC1A, POLG2, NDUFA5, PINK1, ETFB, NDUFV2, IMMP2L, ETFA, MYBBP1A, SCO2 |
| respiratory gaseous exchange | biological process | CFTR, EDNRA, CCBE1, NDN, CSF2RB, MAN2A1, CYSLTR1, HOXA5, FLT4, PBX3, UCP3, MAN1A2, BPGM, SFTPB, NDUFA12, TMPRSS11D, FUT8, COX5B, MECP2, NDST1, DACH1, HNMT, TRAF4, SFTPD, EDN1, SFTPC, ELN, CHRNA4, CHST11 |
| respiratory system development | biological process | PHOX2B, SMPD3, SPRY2, FGF10 |
| respiratory system process | biological process | ADH5, CCBE1, NDN, ZFAND5, AP3B1, HOXA5, FLT4, YWHAZ, STK40, ECEL1, JAG2, TCF15 |
| respiratory tube development | biological process | SHH, HECA, TRAF4, NKX2-8, FOXF1 |
| response to 11-deoxycorticosterone | biological process | CSN1S1 |
| response to 2,3,7,8-tetrachlorodibenzodioxine | biological process | F7, TIPARP |
| response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine | biological process | PTAFR |
| response to 3,3',5-triiodo-L-thyronine | biological process | TOMM20 |
| response to 3-methylcholanthrene | biological process | CHKA |
| response to acetate | biological process | CYP17A1 |
| response to acetylcholine | biological process | CHRNA7, CHRNA3, CHRNB2 |
| response to acidic pH | biological process | SRC, ASIC1, ASIC2, LGMN, SLC9A1, GPR4, CTSS, SST, SERPINF1, ASIC3, GPR65 |
| response to acrylamide | biological process | NEFL |
| response to activity | biological process | IL10, HIF1A, ESR2, BGLAP, CDK1, DNMT1, GSK3B, DNMT3B, ITGB1, CTNNB1, LEP, CAT, IGF1, INSR, CCL5, PLAU, OXT, NTRK1, MAS1, CAB39, CXCR4, HADH, KDM6B, PTN, STAR, PPARD, GCLC, BNIP1, UCP3, PPARGC1A, ADIPOQ, COL4A2, CYBA, OXCT1, PRKDC, CBL, ANGPT2, CRY1, TPH2, ALAD, UQCRC1, BMP6, TH, EDN1, FGF21, SLC25A25, HDAC5, CRY2, SCO2, SMTNL1 |
| response to alcohol | biological process | GLRA1 |
| response to aldosterone | biological process | RPL27, CYBB, CYBA |
| response to alkaline pH | biological process | ACER1 |
| response to alkaloid | biological process | HIF1A, DHX15, PDX1, BCHE, TMED10, UQCRC1, ADORA2A |
| response to aluminum ion | biological process | QDPR, ALAD, LONP1 |
| response to amine | biological process | CDK1, CPS1, RRM2B, ASS1, ITGA2, HNMT, NME1, KCNC1, KCNC2, ADAMTS13, CAD |
| response to amino acid | biological process | IL6, ICAM1, CASP3, MTHFR, GSTP1, MTOR, BAD, IL17A, GPRC6A, CCN2, CPS1, PPP1R9B, ASS1, ASNS, SLC1A2, PEMT, RELA, GLRA3, MEAK7, CDO1, CDKN1B, LYN, ALAD, GLRA1, EDN1, SST, GLRA2 |
| response to amino acid starvation | biological process | EIF2A, EIF4EBP1, LARP1 |
| response to ammonium ion | biological process | ADSS2 |
| response to amphetamine | biological process | SOD1, ICAM1, OXTR, OXT, ASIC1, GRIN1, HDAC2, PPP1R9B, RGS17, HDAC9, PPP1R1B, NR4A2, PDE1B, CALM3, RGS2, RGS10, PPP3CA, HPRT1, RANBP2, TRDMT1, DRD3, TH, DRD1, GRIN2A, SLC18A2, DBH, DRD2, ADORA2A, RGS9, DRD4, RGS4 |
| response to amyloid-beta | biological process | PRNP, CACNA1A, CHRNA7, RAMP3, MMP13, CALCR, DNM1, CACNA1B, AGER |
| response to anesthetic | biological process | HIF1A |
| response to angiotensin | biological process | GSK3B, IQGAP1, CYBB, ROCK2, ROCK1 |
| response to anoxia | biological process | OXTR, CCN2 |
| response to antibiotic | biological process | SOD1, TP53, CYP1A1, IL6, HSP90AA1, CASP3, CASP9, MDM2, CASP8, SKIL, JAK2, ZC3H8, STAR, ENDOG, SLC1A3, ETS1, RSRC1, JAK1, HYAL3, AOC1, CBL, CYB5R4, HYAL2, CIITA, AOC3, UROS, ALPL, VKORC1, CCR4 |
| response to anticoagulant | biological process | F7 |
| response to antidepressant | biological process | DNMT1 |
| response to antineoplastic agent | biological process | RAP1A, PTGR1, RPL18A, ADAM9 |
| response to antipsychotic drug | biological process | SOD1, PRKAR2B |
| response to arachidonic acid | biological process | PPP5C |
| response to Aroclor 1254 | biological process | HPCA |
| response to arsenic-containing substance | biological process | CYP1A1, PTEN, TNFRSF11B, FECH, GCLC, SRRT, RBM4, ALAD, CDKN1A, SERPINF1 |
| response to astaxanthin | biological process | F7 |
| response to ATP | biological process | IL1B, CASP1, PTEN, TRPC3, PANX1, ABCC9, SLC8A1, ASPH, P2RX7, P2RX6, SELL, P2RX4, P2RX5, P2RX3, DGKQ, P2RX2, DNTT, PKLR |
| response to auditory stimulus | biological process | IL6, HIF1A, XPA, XPC, PTN, ABHD12, ERCC8, MDK, SLC26A5, USP53, UCN, KIAA0319, ATP1A2, ATP8A2, KCNC1, CXCL10 |
| response to axon injury | biological process | SOD1, BAX, CDK1, MTR, FLRT3, NTRK1, RANGAP1, AIF1, ARF4, MAX, KCNK2, DPYSL3, MATN2, SARM1, GIPR, P2RY12, APOD, BNIP3, TYROBP, LYN, MORN4, P2RX4, TXN2, EPO, DRD2, MAP1B, FOLR1 |
| response to bacterial lipoprotein | biological process | TLR6 |
| response to bacterium | biological process | IL6, CASP1, TLR4, CCL5, NOS2, WASL, SNX3, FKBP5, ERAP1, BANK1, BAIAP2L1, BAIAP2, RAB29, IFI44, LPL, CD79B, ST13, PLAAT3, CD47, NMES1, STOX2, GPM6A, NEXN, TRDN, STAP1, DGKB, LY6G6C, TENT5A, GBP5, MACROD2, NFIB, SERPINB9, ADIPOQ, DHX58, SLC17A5, ADAMTS9, FCGR2B, RELA, KLHL6, DEFB1, CLPS, ISG15, TMEM229B, IL27, CFLAR, BNIP3, MT1M, FAM20A, FUCA2, LRG1, MS4A1, RGS1, CCDC186, GZMA, SLC11A1, P2RX7, PYGL, IRF8, PYCARD, CA3, BMP2, CYP2E1, GPC3, PNLIPRP2, IRF3, CD40, CUBN, NAALADL2, CEP192, UPK1B, VIL1, OAS2, PENK, CXCL10, CCL2, CD36, CCR4, CAV1, SLC10A2 |
| response to biotin | biological process | HLCS |
| response to bisphenol A | biological process | ESR2 |
| response to cadmium ion | biological process | CDK1, CTNNB1, B2M, CAT, PCNA, CYB5A, MT-CYB, PRNP, HAAO, SORD, GCLC, NUDT1, GOT1, MAPK9, CDKN1B, NPC1, ALAD, MTF1, DTYMK, SLC34A1 |
| response to caffeine | biological process | IL6, DNMT1, DNMT3B, IGF1, PPARG, HDAC2, RYR1, RYR2, DHODH, CAD, ADORA2A |
| response to calcium ion | biological process | IL6, BAD, MT-CYB, ANXA5, ALG2, ANXA7, KCNMB1, TXNIP, SLC25A13, SEC31A, TRPC3, HNRNPD, D2HGDH, CACNG2, AHCYL1, FGG, CAPN3, SYT1, CCND1, THBS1, TSHB, NEDD4, GIPR, ITPR3, TTN, FGB, ANXA11, CALM1, CALM2, CALM3, PDCD6, PTGES, PPP3CA, AQP3, ADAM9, TPH2, S100A16, HOMER1, DUSP1, TRPC1, P2RX7, FGA, MNAT1, SLC25A12, AANAT, PEF1, SDC1, APOBEC1, KCNMA1, PTK2B, SUCNR1, TRPV6, PENK, GDI1, CAV1 |
| response to caloric restriction | biological process | LDLR |
| response to cAMP | biological process | CYP17A1, STAT1, OXT, CREM, LDHA, FOXM1, AREG, PER1, CARM1, CPS1, NDUFS4, THBD, FOSB, CITED1, TEK, RELA, TYR, BIRC2, CDO1, PNPT1, JUNB, FOS, AGXT, DUSP1, DUOX2, SREBF1, PLA2G5, MMP19, VGF, NME1, JUND, PPARGC1B, AANAT, DUOX1, DGKQ, SLC6A3, SDC1, PTK2B, PKLR |
| response to capsazepine | biological process | TRPV1 |
| response to carbohydrate | biological process | IL1B, APOB, HNF1B, MDM2, RAP1A, ME1, ADNP, GOT1, LYN, P2RX3, P2RX2, MAP1B, RAP1B |
| response to carbon dioxide | biological process | F7 |
| response to carbon monoxide | biological process | SOD1, IL10, KCNMA1 |
| response to catecholamine | biological process | RNLS |
| response to ceramide | biological process | PDGFRB |
| response to cesium ion | biological process | CYP2R1 |
| response to chlorate | biological process | PDX1, PTCH1 |
| response to cholecystokinin | biological process | CRK |
| response to cholesterol | biological process | TGFB1, CCL5, CCR5, CCL3, PMVK, F7, HMGCS1, TGFBR1, SMAD2, TGFBR2, ABCA2 |
| response to ciliary neurotrophic factor | biological process | PTN |
| response to cisplatin | biological process | KDM3B, NUCB1 |
| response to clozapine | biological process | PPP1R9B, PRKACB, PRKAR2B |
| response to cobalamin | biological process | MT-CYB, RELA, CD40 |
| response to cobalt ion | biological process | HIF1A, CASP3, CASP9, CASP8, ATF1, D2HGDH, ALAD |
| response to cocaine | biological process | BAX, MDM2, DNMT3B, MBD1, MTOR, TACR3, OXTR, OXT, UBE3A, HDAC2, HTR3A, PPP1R1B, SMPD1, CRH, FADD, CNR1, TIAM1, HNMT, ABAT, CACNG4, PITX3, DRD3, EFTUD2, DRD1, HTR1B, CDK5, MT-ND6, CHRNB2, HDAC5, DRD2, SLC6A3, PTK2B, ADGRL3, RGS4 |
| response to cold | biological process | IL6, ADM, HSP90AA1, CASP8, TRH, HSPA2, HSPD1, PPARG, LPL, TMEM135, PLAC8, UCP3, PPARGC1A, ADRB2, SLC27A1, TRPA1, LRP11, UCP1, ACADVL, MT-CO2, UCP2, FOS, GMPR, CDH8, ADRB1, ATP2B1, ACOT11, VGF, P2RX3, METRNL, THRA, ZNF516, CXCL10 |
| response to copper ion | biological process | SOD1, ICAM1, BAX, CDK1, IL1A, MT-CO1, MT-CYB, PRNP, PAM, SORD, LOXL2, ATP5F1D, ATP7B, ATP7A, SOD3, AANAT, S100A13 |
| response to corticosteroid | biological process | GNRH1, ANXA1, NOTCH1, ENG |
| response to corticosterone | biological process | PTGS1, BAX, TRH, STAR, FOSB, CCND1, CRH, CALM3, FOS, CDKN1A, TH, UCN3, AANAT, NEFL |
| response to cortisol | biological process | IGFBP7, CAD, SLIT3, SLIT2 |
| response to curcumin | biological process | OPA1 |
| response to cycloheximide | biological process | FAS, GHR, BCL2L1 |
| response to cytokine | biological process | TIMP1, IL4, IL6, IL6R, BCL2, FAS, PTGS2, IL6ST, CYP17A1, STAT1, GNAO1, CTNNB1, STAT3, CCL5, OXTR, MCL1, ALDH1A2, AIF1, TIMP2, SKIL, TYMS, CD38, XCR1, CXCL16, COL3A1, PPP3CB, TIMP3, CITED1, CD274, RELA, PDX1, PGGT1B, DDOST, LIFR, NFKB2, REL, SP100, PTGES, JUNB, PML, FOS, MAPKAPK3, AVPR2, BCL2L1, TMEM102, SRF, PLA2G5, TIMP4, TNFRSF11A, OSMR, IL12RB2, CORO1A, JUND, RELB, ITIH4, AANAT, STAT6, RARA |
| response to D-galactose | biological process | NAMPT |
| response to DDT | biological process | CCNB1 |
| response to dehydroepiandrosterone | biological process | CSN1S1 |
| response to denervation involved in regulation of muscle adaptation | biological process | HDAC4, MTMR4, UTRN, FBXO32, MYOG, ACTN3, DAG1, CASQ1, SCN5A, SGCA |
| response to dexamethasone | biological process | IL1B, ESR2, CPS1, GHSR, EDN1, CLDN1, PTAFR, FOXO3, EPO |
| response to dietary excess | biological process | APOE, LEP, PPARGC1A, ACVR1C, GDF3, VGF, SLC25A25, PRLH, RMI1, SGIP1 |
| response to diuretic | biological process | IL1B, PPARG |
| response to DNA damage checkpoint signaling | biological process | ZMPSTE24, SMC1A |
| response to dopamine | biological process | FCSK |
| response to drug | biological process | SOD1, TGFB1, IFNG, IL1B, AMH, CYP1A1, IL4, IL6, ICAM1, INHBA, BCL2, IL10, FAS, SRD5A2, PTGS2, BAX, BAK1, HIF1A, GNAS, ESR2, OGG1, IGF2, BGLAP, CYP17A1, CYP1A2, CDK1, ABCB1, CCNB1, MGMT, XRCC1, DNMT1, HNF1B, CASP3, MTHFR, GSK3B, UBE2B, MDM2, DNMT3B, ITGB1, GNAO1, MGST1, SRD5A1, ABCC1, CTNNB1, STAT3, PGF, PTEN, B2M, BAD, PARK7, CAT, SRC, CCL5, MMP12, PPOX, PMS2, ATR, CDH1, COMT, APEX1, OXTR, PPARG, GATA4, CDK9, FGF8, XPC, EMX1, DUSP6, NTRK1, MT-CYB, LDHA, MYC, MAS1, TOP1, TIMP2, PAM, HDAC4, AACS, USP47, TYMS, CD38, SCN11A, XRCC5, SLC6A2, BLMH, HADH, PLIN2, TXNIP, TNFRSF11B, LPL, SRP19, UQCRC2, FECH, CPS1, PMS1, SORD, HDAC2, PPP1R9B, XPO1, CYBB, RPN2, PTN, STAR, VAV3, AGPAT2, CPT1A, SLC22A12, GNPAT, ASS1, ANXA1, ACSL1, SRP14, SLC1A2, FOSB, PPARGC1A, PNP, POR, SMPD1, CTPS1, AK4, SS18, ADIPOQ, WFDC1, PEMT, FABP3, EEF2, CCND1, CA9, GGH, FZD3, CRH, THBS1, CYBA, MDK, GATA3, SLC1A3, ACTC1, RELA, TRPA1, CENPF, PDX1, OXCT1, SLC26A5, HMGCS1, NFATC2, GAD1, ATG5, APOD, ITGA2, ADRA1A, EMX2, MYO6, BCHE, HADHA, SLC6A11, NEURO |
| response to dsRNA | biological process | PELI1, TLR3 |
| response to electrical stimulus | biological process | IL6, SRC, MT-CO1, OXT, NTRK1, AIF1, AKAP12, HNRNPD, PPARGC1A, NQO1, DISC1, FZD3, OPA1, BTG2, EEF1A2, AKAP9, TACR2, CYFIP1, BRD1, P2RX7, TH, MSTN, GJB6, EPO, S100A13 |
| response to electrical stimulus involved in regulation of muscle adaptation | biological process | PPARGC1A, MYOG |
| response to endoplasmic reticulum stress | biological process | CXCL8, NFE2L2, HSPA5, PDIA3, PLA2G6, WFS1, ATP2A2, DDIT3, DNAJC10, FICD, RNF183, TRIB3, PIK3R1, TMEM259, CREBRF, SEC16A, BCL2L11, P4HB, HSP90B1, XBP1, DNAJB9, TMBIM6, SDF2L1, CREB3, PRKN, MBTPS1, TNFRSF10B, EEF2, PDIA4, AGR2, THBS1, HERPUD1, CREB3L2, ERO1A, NIBAN1, TMX1, ATF4, ERP27, SRPX, TTC23L, FLOT1, STC2, CERT1, ERN1, EIF2S1, UBA5, SEL1L, MBTPS2, NRBF2, MAP3K5, UFM1, DNAJC3, ERP44, PPP1R15A, PTPN1, UFC1, UBE4B, OS9, HYOU1, RASGRF2, EIF2B5, NFE2L1, THBS4, TMEM33, PIK3R2, ERN2, DDRGK1, ATP2A1, TRAF2, PDIA2, RASGRF1, EIF2AK3 |
| response to endothelin | biological process | EDNRB |
| response to environmental enrichment | biological process | ALK |
| response to epidermal growth factor | biological process | MAPK3, MAPK1, ASCL1, TPR |
| response to epinephrine | biological process | GSK3B, PPARGC1A, RNLS, PENK |
| response to erythropoietin | biological process | HAMP |
| response to estradiol | biological process | TGFB1, IL1B, ESR1, PTGS2, AHR, BRCA1, BRCA2, HIF1A, ESR2, OGG1, IGF2, CYP1A2, DNMT1, CASP3, GSK3B, CASP9, CASP8, EZH2, ARNT2, DNMT3B, MBD1, C3, GSTP1, F3, BMP7, SRD5A1, CTNNB1, STAT3, LEP, PTEN, BAD, GH1, CAT, INSR, BMP4, NR2F2, TACR3, OXTR, ALDH1A2, OXT, GC, CCNA2, AREG, PAM, CCN2, RBBP8, CD38, SOCS2, TXNIP, TFPI, HNRNPD, PPP1R9B, CRYAB, PTN, STAT5B, ASS1, ANXA1, F7, FOXA1, RAMP2, NQO1, GHSR, WFDC1, EEF2, CCND1, MMP15, ENDOG, HPGD, POSTN, WNT8B, ETS1, UCN, GHR, SLC6A4, CDKN1B, STRN3, NCOA1, NCOR2, MBD4, CSN1S1, DHH, ESRRA, DUSP1, MBD3, IGFBP2, CD4, TH, PDGFRB, ADCYAP1R1, ARPC1B, GGT1, HTR5A, OPRL1, PTCH1, IHH, CALR, SLC34A1, WNT7A, RGS9, AGT, MAP1B, FGF10, PENK, RARA, Grn |
| response to estrogen | biological process | ESR1, TGFB3, FAS, BRCA1, HIF1A, ESR2, BGLAP, HSP90AA1, HMOX1, MAPK1, GHRL, C3, SRD5A1, CTNNB1, CCL5, PPARG, LDHA, CA2, GBA, GLI3, ASH2L, TNFRSF11B, TRIM25, CTNNA1, STAR, RBBP5, F7, CCND1, CITED1, KMT2D, CRH, GATA3, TEK, TSHB, GHRHR, CITED4, ARSB, SMAD6, APOA1, EP300, CYP27B1, MMP14, KRT19, TPH2, CITED2, DHH, IGFBP2, PDGFRB, TGFBR2, MSTN, ZNF366, ARPC1B, GAL, EPO, DTYMK, WBP2, WNT7A, IL4R, CAV1 |
| response to ethanol | biological process | SOD1, IL1B, IL4, ICAM1, BAK1, ESR2, OGG1, IGF2, BGLAP, CDK1, MGMT, DNMT1, CASP8, GNRH1, GSTP1, TRH, STAT3, LEP, PTEN, BAD, CAT, INSR, IL2, G6PD, NTRK1, MT-CYB, MT-ND4, AACS, TYMS, PSMD14, FECH, GRIN1, HTR3A, STAR, DMAP1, NQO1, IL13, ADIPOQ, PEMT, HMGCR, EEF2, CCND1, GGH, CRH, HPGD, GATA3, ACTC1, ADH6, OXCT1, CLDN18, EIF4EBP1, RPL10A, BIRC2, CDO1, CNR1, RGS2, CBL, SETD7, TNC, TUFM, SETDB1, S100A8, ALAD, ACTR2, ABAT, GRIN2B, SLC2A4, CSF3, EEF1B2, DRD3, HAMP, GRIN3A, AVP, TH, HTR1B, RGS19, MSTN, CA3, CLDN1, CYP2E1, POLB, NPPC, ADCYAP1R1, GRIN2A, KCNC2, CLDN7, GOT2, RBP4, CHRNB2, DRD2, TBXA2R, SLC6A3, APOBEC1, PTK2B, RGS4, PENK, RARA |
| response to ether | biological process | MDM2, OXT, CRH, TH |
| response to exogenous dsRNA | biological process | IFNA1, MAPK3, MAPK1, DDX1, DHX36, RFTN2, DDX21, IFNA8, IRAK3, IFNA10, NFKBIA, RFTN1, RIPK2, CARD9, IFNA2, IFNA14, TLR3, SLC3A2, IRF3, IFNW1, TICAM1 |
| response to external biotic stimulus | biological process | GRP |
| response to external stimulus | biological process | PON1, INHA |
| response to extracellular stimulus | biological process | RPS19, RASGRP4 |
| response to fatty acid | biological process | PTGS1, PTGS2, PON1, CAT, SRC, SCD, CCN2, GNPAT, ASS1, FABP3, GIPR, PDX1, ALAD, HMGCL, SREBF1, FFAR1, FOXO3, CD36, INSIG2 |
| response to fenofibrate | biological process | ABCB4 |
| response to fibroblast growth factor | biological process | IER2, ELK1, TNC, KCNC1, CRKL |
| response to flavonoid | biological process | FIS1 |
| response to fluid shear stress | biological process | NOS3, AKT1, F3, GJA1, PKD1, CITED2, P2RX7, PDGFRB, P2RX4 |
| response to fluoride | biological process | FAS, PON1, FOXO1, FIS1 |
| response to fluoxetine | biological process | MBD1 |
| response to folic acid | biological process | OGG1, MGMT, MTHFR, TYMS, EEF2, ASCL1, BCHE |
| response to follicle-stimulating hormone | biological process | SRD5A2, SRD5A1, TGFBR3, ASNS, GHSR |
| response to food | biological process | CYP1A1, AKT1, G6PD, OXT, BCL10, CPS1, TMEM135, GHSR, CLPS, SREBF1, MPO, SLC16A1, SLC25A25, HSD11B2, LRCOL1 |
| response to fructose | biological process | PTGS2, SLC2A5, PPARGC1A, KHK |
| response to fungicide | biological process | HIF1A, CYP17A1, SRD5A1, KDM5B, KDM6B, STAR, EHMT1 |
| response to fungus | biological process | BAK1, MALT1, BCL10, ATG5, IL25, CARD9 |
| response to gamma radiation | biological process | IL1B, TP53, BCL2, LIG4, BRCA2, BAX, BAK1, GPX1, POLG, TP63, MYC, XRCC2, TRIM13, FANCD2, ERCC6, GATA3, MEN1, PTPRC, PRKDC, CBL, PML, CCL7, TIGAR, POLB, APOBEC1, CXCL10 |
| response to genistein | biological process | ESR2, F7 |
| response to glucagon | biological process | MT-CYB, CCNA2, CPS1, CDO1, QDPR, CRY1, CYC1, SREBF1 |
| response to glucocorticoid | biological process | TNF, IL1B, IL6, BCL2, IL1RN, IL10, FAS, ADM, PTGS2, HIF1A, BGLAP, CASP3, C3, BAD, IGF1, INSR, BMP4, CCL5, PTGDS, FN1, OXT, AIF1, GBA, CPN1, AREG, PAM, TYMS, CPS1, GPR83, CTSV, KRAS, ANXA3, ASS1, ANXA1, UCP3, WNT7B, ADIPOQ, CCND1, MDK, AGL, PDX1, GHRHR, UCN, BCHE, CDO1, GOT1, ADAM9, TPH2, PTPRU, ALAD, HNMT, S100B, AGXT, BMP6, DUSP1, CDKN1A, IGFBP2, TAT, MSTN, CALCR, PPARGC1B, ABCA3, ALPL, HSD11B2, ACSBG1, SDC1 |
| response to glucose | biological process | TGFB1, HIF1A, HNF1B, CASP3, TRH, PTEN, BAD, GJA1, TCF7L2, LDHA, MAPK14, CCN2, SELENOS, NKX2-2, TXNIP, LPL, GYS2, CTSV, PPARD, EIF2B3, EIF2B1, EGR1, ADIPOQ, ACVR2B, THBS1, KHK, SELENOT, SARM1, IRS2, PFKFB2, GIPR, PDX1, SLC30A8, GLUL, GPLD1, COL4A3, NEUROD1, ACVR1C, ILDR2, CDKN1B, SLC8A1, NDUFA9, SIDT2, ANGPT2, FKBP1B, GPAM, EIF2B2, SMAD2, SREBF1, HNF4A, EIF2B5, COL6A2, TGFBR2, UCN3, PFKL, SESN2, TXN2, PRLH, GJD3, PTK2B, APOM, RMI1, EIF2B4, PKLR |
| response to glycine | biological process | GRIN1 |
| response to glycoside | biological process | ATP1A3, ATP1A2, ATP1A1 |
| response to gold nanoparticle | biological process | MPO |
| response to gonadotropin | biological process | ICAM1, CYP17A1, ITGB1, MAS1, FOXM1, CTSV, STAR, HMGCS1, ITGA3 |
| response to gravity | biological process | BGLAP, PKM, FOS, MSTN, MYOG |
| response to growth factor | biological process | FAS, FASLG, SOX2, DUSP6, MYC, SKIL, ANXA3, CDC34, HDAC6, P2RY1, MEIS2, TH, EPHA2, TBC1D7 |
| response to growth hormone | biological process | AKT1, SRD5A1, CPS1, ASS1, F7, GHSR, PHEX, CACYBP, RBBP4, PNPT1, NME2, TRIM16, IGFBP5, SLC34A1 |
| response to heat | biological process | SOD1, IL1B, IL6, NOS3, HSP90AA1, DNMT1, AKT1, HSF1, HSPA2, IGF1, HSPA1A, MT-CYB, DNAJA4, DNAJA2, PSIP1, DNAJB4, TP53INP1, EIF2B3, GCLC, EIF2B1, TGFB1I1, IGFBP7, LRP11, MAP2K7, TRPV2, MICB, EIF2B2, CALCA, EIF2B5, MSTN, SST, P2RX3, TRPV3, CASQ1, CXCL12, ASIC3, EIF2B4, PKLR, TRPV1 |
| response to heparin | biological process | GPIHBP1 |
| response to hepatocyte growth factor | biological process | PLAU, GAB1, CRK |
| response to herbicide | biological process | CYP1A1, CYP17A1, STAR, HTRA2, ALAD, TH |
| response to high light intensity | biological process | RDH13 |
| response to histamine | biological process | DRD3, DRD2, DRD4 |
| response to hormone | biological process | TIMP1, ESR2, AKT1, SNRPN, GHRL, ACAT1, CTNNB1, BAD, INSR, MT-CYB, TIMP2, TAC1, CD38, NCOA4, HADH, SORD, NCOA6, GCLC, ANXA1, F7, TIMP3, ME1, DHCR24, POR, GHSR, MDK, AGL, OXCT1, HMGCS1, ANGPTL3, ADRA1A, FHL2, LOX, STEAP2, MMP14, NCOA1, RBM14, FOXC2, LYN, ALAD, MB, HCLS1, SRF, MMS19, TIMP4, MMP19, SFRP4, TXN2, ANG, PIAS3, LONP1, TUB, PTK2B, NKX2-1, GALP |
| response to human chorionic gonadotropin | biological process | ESR2, GCLC |
| response to hydrogen peroxide | biological process | SOD1, BCL2, BAK1, CDK1, HMOX1, CASP3, GPX1, GNAO1, BAD, PARK7, CAT, SRC, LDHA, KPNA4, MT-ND5, AREG, UBE3A, PDCD10, TXNIP, CAPN2, CRYAB, STAR, APTX, STK25, GLRX2, EEF2, RELA, TRPA1, HBB, PRDX3, SLC8A1, ADAM9, STK26, FKBP1B, ADA, MB, DUSP1, HP, PDGFRB, CRK, NR4A3, MT-ND6, HBA1, SDC1, PTK2B |
| response to hydrogen sulfide | biological process | NQO1 |
| response to hydroperoxide | biological process | GPX1, JAK2, CD38, MT-ND1 |
| response to hydrostatic pressure | biological process | NTRK1, KRT8, COL18A1 |
| response to hydroxyisoflavone | biological process | BGLAP |
| response to hyperoxia | biological process | CYP1A1, CAT, POLG, PLAU, MT-ATP6, MT-ATP8, MT-CYB, HDAC2, BNIP3, CDKN1A, PDPN, PDGFRB, POLB, EPO |
| response to hypobaric hypoxia | biological process | FIS1 |
| response to hypoxia | biological process | TGFB1, IL1B, CYP1A1, ICAM1, MMP2, TGFB3, VEGFA, FAS, CASP1, ADM, PLOD1, HIF1A, HMOX1, FLT1, ERCC2, XRCC1, CASP3, MTHFR, ATM, ARNT2, DNMT3B, TRH, EDNRA, LEP, PGF, TGFBR3, BAD, CAT, IGF1, NOS2, PLAU, PLAT, RAF1, USF1, MT-CYB, LDHA, MT-ND4, CX3CL1, MT-ND5, PAM, FUNDC1, CD38, CXCR4, SCAP, HIF3A, CAPN2, SMAD4, PIN1, CRYAB, HSP90B1, SCFD1, LOXL2, F7, EGR1, RYR1, UCP3, RYR2, CREBBP, ASCL2, PPARGC1A, PDLIM1, RAMP2, PKM, ADIPOQ, AJUBA, REST, CA9, PLOD2, CBFA2T3, THBS1, CYBA, TEK, APOLD1, POSTN, ETS1, ITGA2, CHRNA7, NR4A2, TM9SF4, CFLAR, BIRC2, HMOX2, MECP2, TGFB2, EP300, BNIP3, AHCY, ADSL, SLC6A4, CDKN1B, MMP14, DPP4, SLC8A1, UCP2, WTIP, ANGPT2, PML, VEGFC, SLC2A8, ADA, ALAD, HK2, ABAT, ITPR1, MYOCD, EPAS1, CITED2, EGLN1, MB, ANGPTL4, ATP1B1, MT3, ITPR2, AGTRAP, TH, SRF, TGFBR2, EGLN2, CIAO3, LIMD1, EDN1, SOD3, BMP2, VEGFB, PSEN2, ENG, NPPC, ACVRL1, TXN2, ANG, CHRNB2, CHRNA4, WDR83, EPO, ALAS1, DRD2, P2RX3, HSD11B2, PPARA, ACTN4, LONP1, CXCL12, CYGB, P2RX2, NF1, SMAD3, KCNMA1, PTK2B, PLEKHN1, ALKBH5, LTA, PENK, PKLR, |
| response to immobilization stress | biological process | CYP1A1, VWF, CYP1A2, NR0B1, PPARG, PPP1R9B, CRH, LRP11, GOT1, TPH1, SLC8A1, BRD1, HNMT, ACTR2, FOS, PITX3, TH, TFF1, UCN3, GAL, PTK2B |
| response to inactivity | biological process | IL10, CAT, DRD2 |
| response to inorganic substance | biological process | FAS, BGLAP, PTEN, GART, TNFRSF11B, ATIC, ADNP, RELA, PGAM2, EEF1A2, ALAD, SLC5A1, BAP1, MAP1B |
| response to insecticide | biological process | ESR2, CYP17A1, FECH, STAR, UBA52, TH, MAP1B |
| response to insulin | biological process | IL6, IL10, ADM, GSK3B, LEP, MTOR, CAT, INSR, CCL5, FOXO1, MAX, SCAP, OGT, SESN3, HADH, GRB10, EGR1, UCP3, TSC1, PKM, VPS13C, FABP3, GGH, CITED1, CELA2A, KHK, RELA, SLC27A1, IRS1, GHRHR, MEAK7, UPRT, HADHA, ACVR1C, KBTBD2, PLN, INPP5K, EGR2, GCNT1, LYN, CRY1, SORT1, STXBP3, EIF6, EPM2AIP1, VGF, SESN2, GOT2, GAL, HSD11B2, PRLH, PPARA, AANAT, CAD, ZBTB7B, SRSF5, GALP, INSIG2 |
| response to insulin-like growth factor stimulus | biological process | AKT1, GSK3B, XBP1, PHEX |
| response to interferon-alpha | biological process | IFNAR2, BST2, ADAR, LAMP3, IFITM3, IFITM1, IFITM2, KLHL20, EIF2AK2, MX2 |
| response to interferon-beta | biological process | STAT1, BST2, XAF1, IKBKE, IFITM3, SHFL, PLSCR1, IFITM1, IFITM2 |
| response to interferon-gamma | biological process | MEFV, NUB1, KYNU, BST2, SNCA, CXCL16, UBD, CITED1, IL23R, SLC30A8, SP100, IFITM3, SHFL, CYP27B1, IFITM1, IFITM2, CALCOCO2, GCH1, SLC11A1, CIITA, TRIM21, SEC61A1, ADAMTS13, CD40 |
| response to interleukin-1 | biological process | MTHFR, SRC, HDAC4, CD38, LGALS9, IL1R1, SNCA, IRAK1, MYD88, IRAK2, GCLC, ANXA1, CHI3L1, CITED1, CYBA, RELA, IRAK3, SLC30A8, ETS1, RIPK2, TRAF6, IGBP1, HNMT, TNFRSF11A, TLE5, EPO, TAF9 |
| response to interleukin-11 | biological process | CITED1 |
| response to interleukin-12 | biological process | JAK2, RIPK2 |
| response to interleukin-13 | biological process | CCL11 |
| response to interleukin-15 | biological process | STAT5B, ACSL4, JAK3 |
| response to interleukin-18 | biological process | RIPK2, CLDN1 |
| response to interleukin-2 | biological process | STAT5B, CITED1, JAK3 |
| response to interleukin-4 | biological process | STAT5B, CCL11, CITED1, ADAMTS13, JAK3 |
| response to interleukin-6 | biological process | CHI3L1, CITED1, FOXA2 |
| response to interleukin-9 | biological process | CITED1, JAK3 |
| response to intra-S DNA damage checkpoint signaling | biological process | SLX4, MUS81, FBH1 |
| response to ionizing radiation | biological process | ICAM1, BRCA1, LIG4, BAX, CYP17A1, DNMT1, ATM, DNMT3B, H2AFX, RNF8, DMC1, UIMC1, RNF168, COP1, STAR, CYP2R1, USP28, CLK2, AEN, LZIC, DCLRE1C, BABAM1, RFWD3, TOPBP1, BABAM2, ABRAXAS1, INTS3, KAT5, RRM1, PRKDC, NABP1, ALAD, INIP, EYA1, BRAT1, NABP2, KRT14, MRNIP, BRSK1, PAXIP1, RAD54L, NHEJ1 |
| response to iron ion | biological process | BCL2, MDM2, HFE, FXN, CCND1, ALAD, ABAT, BMP6, TFR2, HAMP, TFF1, C1QA, APBB1, DRD2, SLC6A3, CYBRD1 |
| response to iron ion starvation | biological process | HFE, EIF2AK1, HAMP |
| response to iron(II) ion | biological process | MAP1LC3A, SNCA, PDX1, ACO1 |
| response to iron(III) ion | biological process | CYP1A1, ATP7A |
| response to ischemia | biological process | BCL2, CIB1, FN1, MLYCD, ABRAXAS2, SIRT5, EEF2K, BVES, ROCK2, EGR1, ARID1B, PPARGC1A, STUB1, EEF2, REST, PANX1, PER2, AIFM1, SLC26A5, EIF4EBP1, CPEB4, SQSTM1, PINK1, PPIF, MAP3K5, CX3CR1, HK2, FAIM2, MAP2K6, P2RX7, TREM2, HYOU1, RNLS, TIGAR, P2RX4, CSF1R, PANX2, P2RX2, SLC8A2, CAMK2A, NDNF, TP53, UCHL1, CAV1 |
| response to isolation stress | biological process | KRAS, ACO2, NAPEPLD, TH, HRAS |
| response to kainic acid | biological process | PPP1R9B, PTN |
| response to ketamine | biological process | HPCA |
| response to L-arginine | biological process | DHODH |
| response to L-ascorbic acid | biological process | IL1B, GSTP1, CAT, ITGA2 |
| response to L-glutamate | biological process | GSK3B, TMBIM6, HPCA, AIFM1 |
| response to L-phenylalanine derivative | biological process | PPP1R9B |
| response to laminar fluid shear stress | biological process | TGFB1, TGFB3, ETS1, SMAD6, ADAM9, KLF2 |
| response to lead ion | biological process | DNMT1, APP, CAT, MAP1LC3A, PPP2CA, FECH, STAR, QDPR, ATP7A, ALAD, PPP5C, BACE1, SLC34A1 |
| response to leptin | biological process | STAT3, LEPR, BBS2, STAR, MKKS, CCND1, BBS4, LRP2, NR1D1, EDN1 |
| response to leucine | biological process | PPARGC1A, PIK3C3, PDX1 |
| response to light intensity | biological process | CAT, GNAT2, KCNC1, KCNC2, SLC24A1 |
| response to light stimulus | biological process | OGG1, CLU, POLG, CLOCK, PER3, DYNLRB1, PER1, FECH, ASNS, SLC1A2, BHLHE40, SLC1A3, PER2, ELK1, CRY1, FOS, DUSP1, TH, JUND, RIC8A, DRD2, AANAT, CRY2, RHO, MAPK10, RPE65, SLC4A10 |
| response to linoleic acid | biological process | ADIPOQ, CD36 |
| response to lipid | biological process | BRCA1, PCNA, PPARG, SREBF2, VPS4B, PPARD, PCK2, ABCG1, PDX1, RIDA, GATA2, SREBF1, PDGFRB, NTSR1, PPARA, CD36, INSIG2 |
| response to lipid hydroperoxide | biological process | GPX3 |
| response to lipoic acid | biological process | GLDC |
| response to lipopolysaccharide | biological process | IL1B, CYP1A1, IL6, ICAM1, DCN, TNFRSF1A, TNFRSF1B, IL10, FAS, IL12A, CASP1, ADM, PTGS2, APOB, CYP1A2, DNMT1, MAPK3, MAPK1, CASP3, FASLG, CASP9, HSF1, CASP8, TLR4, GNRH1, MGST1, F3, EDNRA, IGF1, CCL5, NOS2, COMT, F2R, ELANE, SLPI, TAC1, MAPK14, TNFRSF25, ATP2A2, HNRNPA0, ERBIN, JAK2, ADH5, AKAP12, CSF2RB, LGALS9, TFPI, CPS1, HDAC2, PELI1, MGST2, LY96, SNCA, IRAK1, ASS1, THBD, BCR, IDO1, ABR, WDR35, IL13, CXCL6, IL10RA, LIAS, NOTCH1, CITED1, FOXP1, HPGD, PTGER2, RELA, TRIB1, IRAK3, CTSG, PTGER1, TIRAP, IL23R, PTPN22, SELP, IFNAR1, NFKBIA, SMAD6, EDNRB, NFKB2, CNP, CNR1, PRDX3, TAB2, PTGES, CYP27B1, FER, LITAF, JUNB, PTGER4, CD96, S100A8, ALAD, GCH1, S100A7, FOS, SLC11A1, MAPKAPK3, P2RX7, OTUD5, GNG12, MPO, TH, CCR7, TIMP4, TNFRSF11A, EDN1, PTGIR, IL12RB2, GJB6, CLDN1, PTAFR, CD6, AKIRIN2, JUND, GGT1, IRF3, WDR83, SPON2, SRR, PALM3, EPO, ALPL, LBP, TBXA2R, PLCG2, LTA, BDKRB1, FMO1, TRIM6, FGF10, PENK, CXCL10, C5AR1, ATP4B, TICAM1, DUSP10 |
| response to lithium ion | biological process | PTGS2, GSK3B, ARL13B, ASCL1, IGFBP2, EIF2B5, PTK2B, PKLR |
| response to low light intensity stimulus | biological process | HMGCS1 |
| response to low-density lipoprotein particle | biological process | F3, PPARG |
| response to luteinizing hormone | biological process | TGFBR3 |
| response to magnesium ion | biological process | MDM2, C3, TNFRSF11B, D2HGDH, SNCA, CCND1, FGF23, THBS1, BMP6, KCNC2, SLC34A1 |
| response to manganese ion | biological process | PTGS2, INSR, D2HGDH, ADAM9, ATP7A |
| response to manganese-induced endoplasmic reticulum stress | biological process | ATF4, EIF2S1, EIF2AK3 |
| response to mechanical stimulus | biological process | IL6, DCN, HIF1A, BGLAP, CCNB1, F3, IGF1, BMP4, SRC, PPARG, GATA4, DNAH1, ASIC2, TXNIP, KCNK2, SCEL, COL3A1, ASNS, FOSB, IL13, CHI3L1, ENDOG, THBS1, RELA, PSPH, POSTN, LRP11, ETS1, BTG2, MMP14, PIEZO2, ANGPT2, JUNB, TNC, PTGER4, ANKRD23, PPL, FOS, P2RX7, SMPD2, IGFBP2, P2RY1, MEIS2, MPO, TGFBR2, CLCN6, JUND, P2RX3, PTCH1, IHH, CXCL12, ASIC3, PTK2B, BDKRB1, MAP1B, GDF5 |
| response to mercury ion | biological process | ALB, GSTP1, MT-CYB, AQP9, PGAM2, ALAD, TAT, SLC34A1 |
| response to metal ion | biological process | CASP3, FECH, MT1A, CYP2R1, GPHN, NEDD4L, CUTA, MT2A, ALAD, MT1X, MT3, TH, NDRG1, MTF1, PKLR |
| response to metformin | biological process | PPARG, PPARGC1A |
| response to methamphetamine hydrochloride | biological process | PITX3 |
| response to methionine | biological process | PPARGC1A, FGF21 |
| response to methotrexate | biological process | ASNS, DHFR |
| response to methylamine | biological process | GLDC |
| response to methylglyoxal | biological process | SIN3A |
| response to methylmercury | biological process | CYP17A1, FECH, ARSB, ANK2, ALAD, S100B |
| response to mineralocorticoid | biological process | SRC, CCN2, KRAS, HTR1B |
| response to misfolded protein | biological process | CLU, F12, HDAC6, RNF215 |
| response to mitochondrial depolarisation | biological process | SQSTM1, GPS2, BECN1, AMBRA1, ATG13 |
| response to molecule of bacterial origin | biological process | CXCL8, IL10, TLR2, B2M, MALT1, CXCL2, TLR9 |
| response to monosodium glutamate | biological process | GHSR |
| response to morphine | biological process | IL1B, MDM2, GNAO1, EDNRA, MTOR, TACR3, TAC1, CXCR4, MAP1LC3A, PPP2R2A, GRIN1, FOSB, PPP1R1B, RELA, FADD, CNR1, PEA15, NPFF, ADA, PPP5C, PRKCE, PITX3, DRD3, GOT2, SRR, PRKCG, DRD2, RGS4, PENK |
| response to muramyl dipeptide | biological process | MAPK14, ERBIN, NOTCH1, NOD2, RELA, NFKBIA, IRF5, NLRP1, CARD9, INAVA, JAG1 |
| response to muscle activity | biological process | HIF1A, SRD5A1, ATP5PF, TNS2, FNDC5, RYR2, PPARGC1A, CAPN3, OPA1, POSTN, ITGA2, TOMM20, ADSS1, ADSL, FIS1, PRKAA2, MSTN, MYOG, GOT2, METRNL, PERM1 |
| response to muscle activity involved in regulation of muscle adaptation | biological process | MYOG, AGT |
| response to muscle inactivity | biological process | PKM, CASQ1 |
| response to muscle stretch | biological process | RAF1, MAPK14, TCAP, DMD, RYR2, SLC9A1, RELA, NFKBIA, SLC8A1, FOS, EDN1, ANKRD1 |
| response to mycotoxin | biological process | BAK1, ASS1 |
| response to nematode | biological process | CYP1A1, IL25, ITLN1 |
| response to nerve growth factor | biological process | PTN, KCNC1, KCNC2 |
| response to nickel cation | biological process | CACNA1G |
| response to nicotine | biological process | BCL2, IGF2, HMOX1, CASP3, IGF1, NTRK1, MT-ND4, CHRNA5, CHRNE, HDAC2, PPP1R9B, STAR, PPP1R1B, IL13, CHRNA2, CHRNB1, PDX1, CHRNA7, CHRND, CNR1, CHRNA3, ATP1A2, ABAT, CHRNA6, KCNK1, AVP, TH, EDN1, CHRNG, MT-ND6, CHRNB2, CHRNA4, DRD2, SLC6A3, CHRNA1, CHRNB4, PENK |
| response to nitric oxide | biological process | BMP4, EGLN1, CCL19, CCR7 |
| response to nitrogen compound | biological process | NQO1 |
| response to nitrogen dioxide | biological process | TNFSF4 |
| response to nitrosative stress | biological process | DUSP6, ADH5, GCLC |
| response to norepinephrine | biological process | PPARGC1A |
| response to nutrient | biological process | SERPINC1, IL1B, IL4, BRCA1, BRCA2, ERCC1, ALB, LEP, AKR1C3, MTOR, PTEN, IGF1, PPARG, MT-CYB, LDHA, AACS, BCKDHB, OGT, TNFRSF11B, GNAI2, CYBB, STAR, GCLC, LIPG, GNPAT, ACSL3, ASS1, ACSL1, UCP3, PKM, NQO1, POR, ADIPOQ, PEMT, HMGCR, NOD2, AGL, ADIPOR2, GIPR, OXCT1, ARSB, GCGR, BCHE, CD3E, APOA1, CNR1, TTPA, AHCY, ADSL, SLC6A4, COX4I1, SLC8A1, ACSL4, ALAD, HAT1, IGFBP2, HMGCL, SFRP2, TGFBR2, SST, DAD1, CCL28, C2, SLC27A4, EPO, SLC6A19, TBXA2R, SLC34A1, LTA, PKLR |
| response to nutrient levels | biological process | SOD1, IL6, SRD5A2, ESR2, IGF2, BGLAP, CYP17A1, DNMT1, PON1, MBD1, ITGB1, GSTP1, LEP, IGF1, INSR, SRC, CCL5, MMP7, NTRK1, GC, IL15, MAP1LC3A, SIRT5, SORD, RPS6KB1, STAR, CHSY1, ASNS, F7, PPARGC1A, ADIPOQ, OPA1, CYBA, ATF4, PDX1, PSPH, CSHL1, GH2, UCP1, MEAK7, FIS1, SZT2, TPH2, ALAD, SIRT6, MBD3, WNT11, TH, SCT, FOXO4, KAT2A, FGF21, CSH1, SCTR, FOXO3, PROX1, ACACB, CD40, AMBRA1, CSH2, MAP1B |
| response to odorant | biological process | CFAP69, CTSV, MMP14, IL4R |
| response to oleic acid | biological process | BAD, AACS, CPS1, ACSL1 |
| response to organic cyclic compound | biological process | TGFB1, IL1B, AMH, CYP1A1, IL4, IL6, ICAM1, SRD5A2, PTGS2, AHR, BAK1, ESR2, IGF2, BGLAP, CYP17A1, CYP1A2, CDK1, MGMT, HNF1B, CASP3, CASP9, MBD1, GNRH1, GNAO1, SRD5A1, TRH, ACAT1, EDNRA, CTNNB1, STAT3, PTEN, BAD, IGF1, BMP4, CCL5, MMP12, IDH1, G6PD, COMT, OXTR, PPARG, FGF8, DUSP6, OXT, MT-CYB, LDHA, AREG, CCN2, AACS, TYMS, PSMB2, NKX2-2, ANXA7, CD83, PLIN2, ATF1, PPP1R9B, CTSV, CTNNA1, STAR, CPT1A, LONP2, ACSL3, ANXA1, F7, ACSL1, PPARGC1A, NQO1, SLC9A1, CCND1, ERCC8, NAMPT, HPCA, RELA, NEDD8, TRPA1, PDX1, HMGCS1, IGFBP7, ITGA2, BTG2, EDNRB, BIRC2, PTGES, CDKN1B, MMP14, TAF2, ANGPT2, LYN, ALAD, FOS, CDKN1A, DHODH, P2RX7, MBD3, SREBF1, AVP, TH, PDGFRB, TAT, TGFBR2, KAT2A, TET2, KCNC2, TXN2, JUND, SRR, ACACB, PTCH1, AANAT, ABCC4, EIF4A3, SLC6A3, TP53I13, VKORC1, FGF10, MT-ND1, EPHX1 |
| response to organic substance | biological process | SOD1, TIMP1, TGFB1, TNF, CYP1A1, IL10, SRD5A2, ADM, PTGS2, BRCA1, APOB, CYP17A1, CYP1A2, XRCC1, DNMT1, AKT1, CASP3, ALB, STAT3, PTEN, BAD, IGF1, CDH1, PPARG, DUSP6, CA2, ANXA5, AKR1B1, KLF4, GART, PPP2CA, STAR, PPARD, SPP1, CTSC, ACSL1, TIMP3, CLK2, GLRX2, AQP9, PKM, CCND1, ABCG1, SERPINF2, TEK, RELA, TRPA1, HMGCS1, BTG2, SQLE, CRIP1, SLC6A4, DNAAF2, JUNB, FKBP1B, ALAD, S100P, SLC10A3, DUSP1, CDKN1A, BTK, P2RX7, TGFBR2, CDH13, TIMP4, JUND, TRIML2, PPP2R1A, P2RX3, ABCC4, XRCC3, CALR, CASQ1, DGKD, P2RX2, SDC1, ASAH2, NEFL, DUSP10 |
| response to organonitrogen compound | biological process | IL1B, PTGS1, PTGS2, CDK1, GNAO1, MGST1, APEX1, SIN3A, MT-CYB, MT-ND5, AACS, FUNDC1, PSMB2, MAX, MGST3, PPP1R9B, MGST2, CCND1, BTG2, BIRC2, CDO1, NCOR2, CDKN1A, SST, CYP2E1, ABCC4, PTK2B, VKORC1, NNMT, ATP4B, TRPV1 |
| response to organophosphorus | biological process | TYMS, RFC3, TRIM16, PTAFR, AKR1C1 |
| response to osmotic stress | biological process | TSC22D3, SORD, MARVELD3, TSC22D2, AQP9, MAP2K7, NFAT5, ATF2, PLK3, MAPK13, TSC22D4, APOBEC1, KCNMA1, PTK2B, FMO1 |
| response to other organism | biological process | NCK1, WIPF1, KRT8 |
| response to oxidative stress | biological process | SOD1, APOE, BCL2, PTGS1, PTGS2, OGG1, ERCC1, HMOX1, ERCC2, XPA, AKT1, KRT1, APP, GPX1, GPX4, PON2, PARK7, CAT, LPO, IDH1, PRDX2, FGF8, MT-CO1, PRDX1, PRNP, PSMB5, NDUFA6, DGKK, IPCEF1, JAK2, NEIL1, ETFDH, MSRB3, ALS2, TXNIP, MSRA, PSIP1, STK25, GCLC, ERCC6, RRM2B, C19orf12, PRKN, NDUFS2, TPO, DHCR24, OXR1, PDLIM1, NQO1, PXDNL, LIAS, PRDX6, ERCC8, SGK2, EPX, SELENOP, ATOX1, NDUFB4, GPX3, NUDT1, NDUFA12, PSEN1, UCN, NAPRT, PINK1, STC2, PRDX3, PPIF, HMOX2, MMP14, MICB, ABL1, GPX2, PRDX5, MSRB2, ALAD, EPAS1, DUOX2, NDUFS8, VNN1, MT3, OXSR1, MPO, TAT, SCARA3, PAGE4, CA3, SOD3, PXDN, GPX7, TXN2, RGS14, MBL2, CHRNA4, MTF1, DUOX1, TRPM2, CYGB, RBPMS, SLC23A2, NCOA7, LRRK2, HAO1, TP53, SRXN1 |
| response to oxygen radical | biological process | TXNRD2 |
| response to oxygen-glucose deprivation | biological process | BNIP1, BNIP3 |
| response to ozone | biological process | IL1B, CAT, FN1, EDN1, CYP2E1 |
| response to paclitaxel | biological process | WDR35 |
| response to pain | biological process | COMT, TAC1, SLC6A2, CRH, TRPA1, UCN, EDNRB, GCH1, NMUR2, CALCA, RET, GJA4, PRKCG, DBH, CACNA1B, RELN, TRPV1 |
| response to parathyroid hormone | biological process | GNAS, CITED1, ITGA2, SLC34A1 |
| response to peptide | biological process | OXTR, PXN, CRK, AANAT, CD40, SLC34A1 |
| response to peptide hormone | biological process | TIMP1, IL1B, FAS, SRD5A2, STAT1, GNRH1, BMP7, STAT3, GNAI1, GJA1, OXTR, OXT, MAS1, AREG, CCN2, REG3A, STAR, STAT5B, EIF2B3, REG1B, EIF2B1, ASS1, ANXA1, TEK, REG3G, IRS1, LRP6, BTG2, EREG, STC2, CDKN1B, RNF40, LYN, EIF2B2, STAT2, LRP5, SREBF1, EIF2B5, TH, TIMP4, TFF1, DAG1, NR4A3, JUND, HHEX, PRLH, STAT6, STAT5A, CXCL12, SLC34A1, EIF2B4, NEFL, TRPV1 |
| response to peptidoglycan | biological process | IL6, IRAK3, IRF5, CARD9, INAVA, C5AR1 |
| response to pH | biological process | GJA1, CA2, GBA, PAM, ASIC1, CLCN7, HVCN1, ARSB, TTPA, TRPV1 |
| response to phenylpropanoid | biological process | CAT |
| response to pheromone | biological process | VN1R2, GPR180, VN1R3, TMEM145 |
| response to phosphatidylethanolamine | biological process | CRLS1 |
| response to platelet-derived growth factor | biological process | FER |
| response to platinum ion | biological process | ALB, FECH, ALAD, UROS |
| response to potassium ion | biological process | GNRH1, CLU, SLC26A5, KCNC1, ADAMTS13, SLC34A1 |
| response to progesterone | biological process | TGFB1, TGFB3, CATSPER1, CATSPER2, C3, BAD, OXTR, OXT, NR1H3, CATSPER4, CATSPER3, GABRB1, UBE3A, TYMS, CD38, NKX2-2, TXNIP, PTN, CATSPERB, FOSB, RAMP2, THBS1, PTGER2, RELA, ABHD2, DSG1, CATSPERG, TGFB2, NCOA1, CATSPERD, YAP1, CSN1S1, FOS, SREBF1, DSG2, CLDN4, WBP2, CAV1 |
| response to prolactin | biological process | GNRH1, EEF2K |
| response to prostaglandin E | biological process | GNRH1, TGFBR3, OXT, PPP1R9B, CCL19, CCR7, AANAT, CCL21 |
| response to prostaglandin F | biological process | YY1, EDN1 |
| response to protozoan | biological process | VTCN1 |
| response to psychosocial stress | biological process | ADRB2, GLP1R, PRKCG |
| response to purine-containing compound | biological process | HIF1A, AACS, ADSS2, HMGCS1, TRPM2 |
| response to pyrethroid | biological process | DDC, SCN1B, TH, SCN2B |
| response to radiation | biological process | TGFB1, BCL2, PTGS2, FKBPL, OGG1, IGF2, CDC25A, CAT, KIT, NTRK1, POLH, COL3A1, CCL11, FANCG, F11R, ANGPT2, JUNB, SMC1A, LRP5, BCL2L1, TNFRSF11A, PLK3, BACE1, JUND, CXCL12, PENK, CCR4 |
| response to rapamycin | biological process | HNRNPD |
| response to reactive oxygen species | biological process | SOD1, APOE, SOD2, GSR, GPX1, GSTP1, CAT, CYCS, PRDX2, PRDX1, NOX5, COA8, NUDT15, TRA2B, PPARGC1A, APOD, S100A7, HYAL2, PLK3, PTK2B |
| response to redox state | biological process | CLOCK, NPAS2, SELENOS, ADH5, RYR2, GLRX2, SIRT2, FKBP1B, ARNTL |
| response to retinoic acid | biological process | CYP17A1, HSD17B2, IGF2R, BMP4, PPARG, OXT, KLF4, CD38, ASXL1, TMEM161A, TIE1, CLK2, WNT9B, OVCA2, CYP26A1, DKK1, CDKN2D, IGFBP7, WNT8B, ASCL1, GDAP2, SP100, PTGES, NCOA1, MICB, AQP3, DNAAF2, SLC10A3, BMP6, DUSP1, IGFBP2, SREBF1, PDGFRB, TRIM16, RXRG, RBP4, RARG, TRIML2, CTSH, PTCH1, ACER2, GDAP1, RARA |
| response to rotenone | biological process | KIF1B |
| response to salicylic acid | biological process | SLC26A5 |
| response to salt | biological process | ESR2, SLC26A5, RIDA, EDN1, RNLS |
| response to salt stress | biological process | TNF, BAX, HIF1A, HSP90AA1, CCL5, ANXA7, BDKRB2, PAPPA2, TH, EPO, TP53 |
| response to selenium ion | biological process | APOB, GPX1, SELENOM, SELENOW, ALAD |
| response to silver ion | biological process | TCIRG1 |
| response to sodium arsenite | biological process | NEFL |
| response to sodium phosphate | biological process | HNRNPD, FGF23, PHEX |
| response to starvation | biological process | ADM, ACAT1, PPARG, PDK4, AACS, DDIT3, CPS1, BNIP1, GNPAT, PPARGC1A, PCK2, FSTL1, ULK2, GPT, OXCT1, LRP11, ULK1, GCGR, ADSS1, ADSL, CBL, FOXK2, ZFP36, BCAS3, DHODH, HMGCL, HCRT, PAGE4, SSTR3, TBC1D5, UCN3, FOXO3, FOXK1, CAD |
| response to statin | biological process | IL1B |
| response to steroid hormone | biological process | BCL2, SRD5A2, CYP17A1, MDM2, GNRH1, IGF1, ACR, IDH1, OXTR, OXT, CA2, GC, RBBP7, CPS1, PAQR8, PPP1R9B, STAR, SPP1, ASS1, UCP3, CCND1, LOX, IGFBP2, TH, TGFBR2, SST, HSD11B2, ABCA2, PAQR7 |
| response to sterol depletion | biological process | LYN, INSIG1, PIP4P1, INSIG2 |
| response to stilbenoid | biological process | IL1B, CIDEA, LY6D, CD36 |
| response to stimulus | biological process | TAS2R38, OR2W3, LCN1, CFAP69, OR12D2, OR2AG2, NDP, BBS2, OPA3, RCVRN, PPT1, OR10AD1, OR5AR1, RPGRIP1, NYX, OR52D1, OR5V1, BBS5, OR9A4, OR51A7, TAS2R9, PPEF2, PDE6D, OR1G1, PDCL, CNGA2, SLC24A5, RIMS1, SLC24A4, OR9Q2, RPGR, OR51V1, TAS2R19, TAS1R2, OR52A1, TULP1, TIMP3, ABCA4, OPN5, OR1L6, MKKS, VSX1, PCARE, GRM8, TAS2R50, BBS9, OR1N2, OR6B3, USH2A, GNAT2, OR10J1, RP1, OR1D5, OR10A3, OR2T33, OR52E4, MYO3B, OR2H1, ARL6, OPA1, OR2J2, PDE6A, UNC119, OR56A4, OR10Q1, OR13C4, OR2T4, OR4X1, WDR36, OR5P2, OR2M4, OR4C12, BBS4, OR5B21, TRPA1, OR5F1, GUCY2F, TAS2R60, OR5I1, CNNM4, OR2L13, DTNBP1, TAS2R8, SLC45A2, NR2E3, SCNN1G, RSPO2, OR4D11, OR8D4, OR13A1, OR13C8, OR5R1, OR5K1, OR52B2, GUCA1A, OR51B6, SLITRK6, OBP2A, OR51B5, PIEZO2, OR2S2, OR7C2, TACSTD2, FAM161A, ADGRV1, TGFBI, CRY1, CLIC5, SCNN1A, OR3A1, IRX5, OR10A4, CNGB3, CABP1, OR2A4, CRYGD, OR1E1, ROM1, RSPO3, NRL, MYO3A, RAX2, OR2W1, OR10H1, GRM6, OR7C1, PDE6G, SCNN1D, GUCY2D, CALHM1, ZNF513, AIPL1, CRX, RLBP1, RD3, RDH5, RDH12, RDH8, CRYAA, LCTL, HPS1, TAS2R1, |
| response to stress | biological process | EGFR, HSP90AA1, MAPK1, MTOR, MAPK8 |
| response to sucrose | biological process | ERCC1, OXT, ADIPOQ, KHK |
| response to sulfur dioxide | biological process | ICAM1 |
| response to superoxide | biological process | SOD1, SOD2, ERCC6, UCP3 |
| response to symbiotic bacterium | biological process | GPX1, C4BPB, PTAFR |
| response to tellurium ion | biological process | HMGCS1 |
| response to temperature stimulus | biological process | F3, GLRX2, ERO1A, UCP1, TRPV2, ACOT11, P2RX3, TRPV3 |
| response to testosterone | biological process | SRD5A2, ESR2, BGLAP, DNMT1, GNRH1, SRD5A1, BAD, INSR, BMP4, GBA, HOXD13, NASP, NKX3-1, CA9, THBS1, PSPH, CFLAR, PLN, XRN1, CBL, FOXP2, DUSP1, AVP, HOXB13, MSTN, EDN1, NME1, MTAP, EPO, TBXA2R, CAD, CALR |
| response to thyroid hormone | biological process | ANXA2, GBA, ANXA5, AKR1B1, CAB39, F7, PPARGC1A, HPN, SLC26A5, SLC34A1 |
| response to Thyroid stimulating hormone | biological process | F7 |
| response to thyrotropin-releasing hormone | biological process | F7 |
| response to thyroxine | biological process | F7, CRLS1 |
| response to TNF agonist | biological process | RPS3 |
| response to toxic substance | biological process | CYP1A1, BCL2, FAS, AHR, BAX, CYP17A1, CDK1, CCNB1, MGMT, XPA, DNMT1, PON1, MAPK3, MAPK1, MDM2, DNMT3B, GPX1, GSTP1, HSPA9, PON2, CAT, CCL5, CHKA, SLC6A14, CDH1, EPHX2, CYP1B1, MT-CYB, GABRB1, GJC2, TYMS, DHRS2, BLMH, CPS1, WAPL, CES1, STAR, SCFD1, CCL3, ERCC6, GLYAT, ASS1, ASNS, WDR35, ARHGAP33, NUPR1, NQO1, DDC, DHX15, SLC7A8, AIFM1, ATF4, PDZD3, CNP, TTPA, MBP, SLC6A4, LYN, ALAD, FOS, CDKN1A, SLC23A1, PDGFRB, SRF, MPST, BRIP1, CLDN1, KCNC1, KCNC2, SLC18A2, ADAMTS13, AQP10, DRD2, SNN, SLC22A8, SDC1, TRPM6, SLC30A4, INMT, PENK, EPHX1, NEFL |
| response to transforming growth factor beta | biological process | ITGB1, SMAD4, ROCK2, CITED1, ZFHX3, ROCK1, MXRA5, MEN1, FNDC4, EDN1, ENG |
| response to transition metal nanoparticle | biological process | GOT1 |
| response to tumor cell | biological process | HNMT |
| response to tumor necrosis factor | biological process | PTGS2, CASP3, CASP8, INSR, CCL5, NUB1, JAK2, CXCL16, UBD, CHI3L1, ADIPOQ, ENDOG, MAP4K3, TRIM32, MAP2K7, ADAM9, IGBP1, GCH1, AFF3, TNFRSF11A, GGT1, ADAMTS13 |
| response to type I interferon | biological process | IKBKE, MX1, ISG15, SHMT2, SP100, SHFL, TRIM56 |
| response to type III interferon | biological process | SHFL |
| response to ultrasound | biological process | GSK3B, CXCR4, CXCL12 |
| response to unfolded protein | biological process | HSP90AA1, HSPA4, HSPB1, HSPA2, HSPD1, HSPA1L, HSPA8, UBXN4, HSPH1, DERL2, DDIT3, FICD, HSPA14, EDEM2, EDEM3, CREBRF, FAF2, DERL1, DNAJB4, VAPB, XBP1, DAB2IP, STT3B, DNAJB9, TMBIM6, JKAMP, CREB3, MANF, THBS1, HERPUD1, CREB3L2, ERP27, PARP16, DNAJC4, TMEM129, ERN1, MFN2, HSPA13, YOD1, DNAJC3, UBE2J2, ERP44, FBXO6, DNAJB1, CREB3L3, TOR1B, HSPB3, EDEM1, HERPUD2, HSPA6, ATF6B, THBS4, CHAC1, DNAJB2, COMP, HSPE1, SERPINH1, EIF2AK3, HSPA1A, HSPA1B, HSPB7 |
| response to UV | biological process | USP1, ERCC2, XPA, CASP3, CASP9, UBE2B, CAT, MAPK8, ELANE, USF1, KIAA0101, RO60, REV1, TIPIN, ERCC6, DDB2, DTL, UVSSA, ERCC5, ERCC8, MAP4K3, TRIM32, MSH6, CDKN2D, MEN1, MAP2K7, TYR, CCAR2, ZRANB3, HUS1, PML, ERCC4, UBE4B, CDKN1A, SPRTN, TREX1, POLD1, TP53I13, BRSK1, PRIMPOL, RAD18, TP53 |
| response to UV-A | biological process | EGFR, AKT1, CCND1 |
| response to UV-B | biological process | BCL2, IL12A, XPC, MSH2, HMGN1, ERCC6, RELA, IVL |
| response to UV-C | biological process | BRCA2, BAK1, HMGN1, POLH, MAP3K4, BCL3, ERCC5, YY1 |
| response to virus | biological process | TNF, IFNG, CYP1A1, IL12A, APOB, HSPB1, ENO1, CLU, IFNAR2, SRC, CCL5, SPACA3, NPC2, EEF1G, CCT5, DDX1, TBK1, DDX3X, PSMA2, CXCR4, IFIH1, CCL8, IFI44, DHX36, IVNS1ABP, OAS1, BST2, LAMTOR5, PRKRA, IFNGR1, BCL3, GTF2F1, ADAR, ISG20, DDX21, CCL11, AP1S1, ZC3HAV1, ODC1, IFNGR2, DHX58, STMN1, OASL, RSAD2, IFIT1, GATA3, IRAK3, CCL22, CCDC130, MX1, HMGA2, IFNAR1, IKBKG, URI1, RPS15A, CDK6, IFITM3, HYAL3, IFITM1, IFITM2, BATF3, CREBZF, DCLK1, IFIT2, HNRNPUL1, TNFSF4, HYAL2, CCL19, DUOX2, IKBKB, FGR, TPT1, EIF2AK2, BCL2L1, DDX60, IRF7, TBX21, MX2, MST1R, XPR1, TLR3, PIM2, IFNW1, CXCL12, CHRM2, OAS2, BTBD17, IFIT3, CXCL10, ACTA2, TRIM22 |
| response to vitamin | biological process | PEMT, NNT, PDX1, SETDB1, ALAD |
| response to vitamin A | biological process | CYP1A1, DNMT1, DNMT3B, CAT, PPARG, GATA4, ALDH1A2, TYMS, PPARD, CYP26A1, TSHB, HAMP, EPO, SLC34A1, MAP1B, RARA |
| response to vitamin B1 | biological process | ALAD |
| response to vitamin B2 | biological process | MTHFR |
| response to vitamin B6 | biological process | KYNU |
| response to vitamin D | biological process | TGFB1, IL1B, PTGS2, CYP24A1, BGLAP, BMP7, INSR, TRIM25, SPP1, CDKN2D, PHEX, TYR, STC2, CYP27B1, AQP3, CD4, ALPL, CXCL10 |
| response to vitamin E | biological process | LEP, CAT, CCND1, HMGCS1, FKBP1B, ADA, ALAD, SRSF2 |
| response to vitamin K | biological process | BGLAP, F7 |
| response to water | biological process | PKD2L1 |
| response to water deprivation | biological process | ESR2, CD9, AKR1B1, LRP11, ATF2, TH, MAPK10 |
| response to water-immersion restraint stress | biological process | FOXO4, FOXO3 |
| response to wounding | biological process | TGFB1, CYP1A1, IL6, ADM, BAX, VWF, CASP3, GPX1, CLU, F3, FN1, F2R, SOX2, CCN2, NMNAT1, F2RL3, CCR1, PDGFB, TMIGD3, SLC1A2, MDK, SLC1A3, ID3, CREB3L2, PHB2, ABHD2, MAP2K4, PDX1, DST, ODAM, KLK8, ETS1, PDGFA, LYVE1, ITGB4, TGFB2, GRIN2C, ZFP36L2, RAC1, ADORA3, TNC, CX3CR1, FGFR1OP2, ZFP36, ZFP36L1, GLI1, F2RL2, FGF7, HOXB13, CDK5, GRIN2A, ECRG4, NRP1, HHEX, WDR83, F2, VASH1, TMPRSS4, KLK6, SULF2, MAP1B, RIPOR1, PLLP, GAP43, AGER |
| response to X-ray | biological process | TP53, LIG4, BRCA2, HIF1A, ERCC1, CASP3, TP63, MSH2, XRCC2, KARS1, ERCC6, ANXA1, THBD, CCND1, ERCC8, XRRA1, XRCC4, CDKN1A, BLM, IKBIP |
| response to xenobiotic stimulus | biological process | AHR, GPX1, GCLC, SLITRK5, TIGAR, AHRR |
| response to yeast | biological process | IL6, ADM, APP, ELANE, TAC1, CAMP, NPY, CALCA, MPO, CRK, ANG |
| response to zinc ion | biological process | BGLAP, PTEN, CA2, PAM, HAAO, SLC30A5, CPS1, D2HGDH, ASS1, SLC30A2, HVCN1, GGH, KHK, SLC30A8, CRIP1, PLN, SLC39A13, ATP7A, S100A8, ALAD, P2RX7, HAMP, TH, SLC30A3, ZACN, KRT14, AANAT, APOBEC1, SLC30A4 |
| reticulophagy | biological process | RB1CC1, RETREG1, RETREG3, STING1 |
| retina development in camera-type eye | biological process | IL4, LIF, SOX9, BAX, BMP4, BMPR2, NPHP1, CHD7, NPHP4, CLCN2, MYH10, MAX, RPGRIP1, PFDN5, PTN, TULP1, GNB1, XRN2, RP1, OPA1, CALB1, SKI, PDE6A, HPCA, NTRK2, MFRP, NEUROD4, NR2E3, LHX1, DCX, TENT2, RRM1, TBC1D32, CRB1, MDM1, POU4F2, NECTIN1, VAX2, GRM6, RET, ZNF513, IMPDH2, RD3, LAMC3, DLL1, TCIRG1, LPCAT1, TGIF2, SERPINF1, PDE6B, RHO, MERTK, RP1L1, TUB, LHX2, RPE65, PRPH2 |
| retina homeostasis | biological process | SOD1, ALB, TF, KRT1, HSPB1, LYZ, B2M, LTF, ACTB, PIP, AZGP1, LCN1, PRDX1, SLC28A2, TULP1, CCDC66, WDR36, BBS4, PIGR, ACTG1, ZG16B, POC1B, AIPL1, ATP1B2, CST4, CDH3, CNGB1, PRR4, WHRN, POTEF, RPE65 |
| retina layer formation | biological process | AHI1, HIPK1, FJX1, ARL6, CALB1, LHX1, TFAP2A, HIPK2, PTPRM, ATP8A2, TSPAN12, CRB1, RDH13, DSCAM, SDK2, SDK1, MEGF11, FOXN4, TOPORS, PTF1A |
| retina morphogenesis in camera-type eye | biological process | MAN2A1, RP1, MFSD2A, CRB1, ROM1, LRP5, DLL1, PROX1, RPE65, PTF1A |
| retina vasculature development in camera-type eye | biological process | HIF1A, BMPR2, CYP1B1, ACVR2B, ROM1, PDGFRB, PDGFRA, ACVRL1 |
| retina vasculature morphogenesis in camera-type eye | biological process | NDP, FZD4, CLIC4, LRP5, RHOJ, NRP1 |
| retinal bipolar neuron differentiation | biological process | VSX1, IRX5, CABP4, ZHX2 |
| retinal blood vessel morphogenesis | biological process | CYP1B1, FZD4, COL4A1, LRP5, LRP5L |
| retinal cell programmed cell death | biological process | BAX, FASLG |
| retinal cone cell apoptotic process | biological process | DIO3 |
| retinal cone cell development | biological process | GNAT2, RP1, USH1C, HCN1, THY1, CABP4, DIO3, TOPORS |
| retinal ganglion cell axon guidance | biological process | ISL1, EPHB2, SLIT1, ROBO2, EFNA5, EPHB1, NRCAM, PTPRM, ALCAM, POU4F2, EPHA7, NRP1, EPHB3, SLIT2 |
| retinal metabolic process | biological process | AKR1C3, CYP1B1, ALDH1A2, BCO2, ALDH1A3, RDH13, RDH10, RDH11, ALDH8A1, BCO1, AKR1C1, RPE65 |
| retinal pigment epithelium development | biological process | TBC1D32, MFSD2A, IHH |
| retinal rod cell apoptotic process | biological process | AKT2 |
| retinal rod cell development | biological process | RP1, NTRK2, BBS4, NRL, NAGLU, TRPM1, TOPORS |
| retinal rod cell differentiation | biological process | SOX9, PTN |
| retinoic acid biosynthetic process | biological process | ALDH1A2, DHRS9, RBP1, ALDH1A3, RDH10 |
| retinoic acid catabolic process | biological process | CYP26B1, CYP26A1, CRABP1, CYP26C1, CYP2W1 |
| retinoic acid metabolic process | biological process | CYP26B1, ALDH1A2, UGT1A8, ADH1A, CYP2C8, BCO2, CYP26A1, ADH6, ALDH1A3, ADH1B, SCPEP1, CYP3A5, CYP2C18, ALDH8A1, CYP2S1, CRABP2, UGT1A9, UGT1A3, UGT1A7 |
| retinoic acid receptor signaling pathway | biological process | CYP26B1, ALDH1A2, CREM, ESRRG, RARB, SP100, PML, SNW1, RXRG, RARG, ACTN4, CRKL, RARA, NR1H2, PTF1A |
| retinoid metabolic process | biological process | APOE, APOB, AKR1C3, AKR1B1, GPC2, ADH4, ADH5, DHRS3, LPL, GPC5, SDC2, ABCA4, SDC4, GPIHBP1, GPC6, RBP1, BCO2, AKR1B10, NAPEPLD, CLPS, ADH1B, APOA1, LRP2, RBP2, HSPG2, LRP1, GPC4, ALDH1A1, RDH10, RDH11, RLBP1, RDH5, RDH12, GPC1, RARRES2, RBP4, GPC3, AGRN, APOC3, RHO, STRA6, SDC3, SDC1, PLB1, BCO1, APOM, PNLIP, AKR1C1, RPE65, RBP3, AKR1C4 |
| retinol metabolic process | biological process | AKR1C3, CYP1B1, ALDH1A2, AKR1B1, ADH4, DHRS3, DHRS9, DGAT2, ADH1A, CYP2C8, RDH14, AKR1B10, ADH6, ALDH1A3, DGAT1, ADH1B, PNPLA4, CYP3A5, RDH13, RETSAT, ALDH1A1, RDH10, RDH11, RDH5, RDH12, RDH8, RBP4, CYP2D6, PLB1, BCO1, RPE65 |
| retinol transport | biological process | RBP4, STRA6 |
| retrograde axonal protein transport | biological process | DLG2 |
| retrograde axonal transport | biological process | SOD1, SNAPIN, DST, TMEM108, HAP1, NEFL |
| retrograde axonal transport of mitochondrion | biological process | AGBL4, ACTR10 |
| retrograde neuronal dense core vesicle transport | biological process | KIF5B, KIF1C, KIF1B, KIF5A, KIF1A |
| retrograde protein transport, ER to cytosol | biological process | SELENOS, DERL2, FAF2, DERL1, HSP90B1, UFD1, HERPUD1, SEC61B, TMEM129, SEL1L, ERLEC1, OS9, SYVN1, AUP1, NPLOC4 |
| retrograde trans-synaptic signaling by endocannabinoid | biological process | CNR1, DAGLB, DAGLA |
| retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission | biological process | GUCY1A1 |
| retrograde trans-synaptic signaling by trans-synaptic protein complex | biological process | TENM2, DAG1 |
| retrograde transport, endosome to Golgi | biological process | RAB9A, DENND2A, EVI5, VPS26A, PHETA2, VPS29, RAB29, VPS52, MAGEL2, SNX6, SNX2, GOSR1, RAB6B, PIKFYVE, STX10, STX5, WASHC2A, VTI1B, PHETA1, BET1L, RAB6A, AP1S1, VPS26B, SNX32, SNX8, TBC1D23, ANKFY1, DENND5A, TBC1D10C, SNX5, RAB7A, ERC1, VAMP3, STX16, RHOBTB3, VPS53, ARL1, PREPL, TBC1D10B, HEATR5B, GOSR2, CLTCL1, CLTC, RAB6D, VPS50, RNF126, RIC1, GCC2, TMEM87A, RGP1, VPS51, GGA1, SLC66A2, VTI1A, PLEKHJ1, GBF1, TBC1D5, ARFRP1, YKT6, BAIAP3, UBE2O, TBC1D17, VPS35, WASHC2C, HEATR5A, RAB9B |
| retrograde transport, endosome to plasma membrane | biological process | VPS26A, VPS29, ANKRD50, CCDC93, SNX27, ENTR1, ANKRD27, VPS26C, RAB11B, VPS35L, CCDC22, SNX17, MICALL1, VPS39, VPS35, WASHC2C |
| retrograde transport, plasma membrane to Golgi | biological process | USP6NL |
| retrograde transport, vesicle recycling within Golgi | biological process | CUX1, GOLGA5 |
| retrograde vesicle-mediated transport, Golgi to ER | biological process | PICK1, KIF3B, KIF3A, ARF4, ARCN1, PITPNB, CENPE, KIF2A, SURF4, ZW10, KIF1C, SEC22B, KDELR2, USE1, COPB2, COPB1, COPZ1, RAB1A, KLC2, RAB6B, KIF15, KDELR3, NSF, SCFD1, KIFAP3, ERGIC2, KLC1, BNIP1, STX18, COPE, RAB6A, NBAS, LMAN2, DNAJC28, ARF5, COG4, ARFGAP1, TMED2, ARF3, ATP9B, KIF5A, KIF2B, ATP9A, COPG1, TAPBP, GOLPH3L, GOLPH3, KIF18A, BICD2, ARFGAP3, TMED7, RER1, TMED10, RAB6D, UVRAG, COPA, SCYL1, NAPA, KDELR1, HTT, COG7, TMED9, KIF4A, COG3, COPG2, PLPP3, KIF3C, RINT1, GBF1, KIF23, ERGIC3, ARFGAP2, ERGIC1, KIF26A, KIF4B, RAB1B, COPZ2, KIF11, KIF22 |
| retrotrapezoid nucleus neuron differentiation | biological process | PHOX2B |
| reverse cholesterol transport | biological process | APOE, CLU, CES1, LIPG, SCARB1, ABCG1, LIPC, ABCA5, APOA1, CETP, APOC3, APOM, LCAT |
| Rho protein signal transduction | biological process | EDNRA, ARHGEF3, CDC42EP5, BCL6, ARHGEF11, ROCK2, CNKSR1, RHOD, RHOG, AGTR1, ROCK1, ARHGEF12, CDC42EP2, ADRA2A, ARHGAP5, CELSR1, CDC42EP3, ROPN1B, CDC42EP4, HACD3, COL1A2, CDC42EP1, GNA12, EPS8, VANGL2, ARHGAP1, ARHGAP29, ARHGAP6, CTNNAL1, ARHGDIB, ARHGEF1, PDPN, ARHGDIG, CDH13, RTKN, TAX1BP3, WAS, ARHGAP4, RHOJ, NGFR, PECAM1, PHACTR4, LIMK1, MYO9B, EPS8L1, SYNJ2BP, RIPOR1 |
| rhodopsin mediated signaling pathway | biological process | GNB1, PDE6A, GNGT1, SAG, PDE6G, CNGB1, PDE6B, RHO, GRK1 |
| rhombomere 2 development | biological process | HOXA2, GBX2 |
| rhombomere 3 development | biological process | HOXA2, EGR2, HOXB2 |
| rhombomere 3 formation | biological process | EGR2 |
| rhombomere 3 morphogenesis | biological process | HOXA2 |
| rhombomere 3 structural organization | biological process | EGR2 |
| rhombomere 4 development | biological process | HOXB2 |
| rhombomere 5 formation | biological process | EGR2 |
| rhombomere 5 structural organization | biological process | EGR2 |
| rhombomere development | biological process | HOXB3 |
| rhythmic behavior | biological process | EGR2 |
| rhythmic excitation | biological process | EDN1 |
| rhythmic process | biological process | TP53, AHR, NRIP1, SP1, GSK3B, EZH2, MAPK8, NCOA2, PPARG, PROK2, CLOCK, TOP2A, KDM5C, CREM, SIN3A, NPAS2, TOP1, PER3, HNRNPU, UBE3A, NR1D2, KDM5B, KLF9, OGT, PER1, CBX3, PSPC1, MAGEL2, SIAH2, SFPQ, GFPT1, HNRNPD, HUWE1, HDAC2, FBXW7, LGR4, BTRC, MAGED1, CSNK1E, RACK1, SETX, DTL, ROCK2, EGR1, ENOX1, CREBBP, PPARGC1A, TEF, BHLHE40, PPP1CB, NAMPT, ID3, NONO, TIMELESS, PER2, ATF4, RORA, CSNK1D, HLF, DBP, HES7, USP2, NFKB2, FBXL3, CSNK2A1, KMT2A, EP300, CDK5R1, CCAR2, NFYA, MAPK9, PRKDC, TWIST1, KLF10, USP7, KDM2A, MYCBP2, PML, CRY1, CAVIN3, PRKAA2, USP9X, SUV39H2, HDAC3, NCOR1, NR1D1, GPR176, RAI1, CIPC, HNF4A, ID2, ARNTL, CDK5, THRAP3, NGFR, KDM5A, KDM8, RELB, NFIL3, PROX1, KAT2B, MYBBP1A, PRKCG, SIK1, PPARA, AANAT, CRY2, CRTC1, RORC, OPN4, MAPK10, SPSB4, DRD4, DDB1, MC3R, NKX2-1, BHLHE41 |
| rhythmic synaptic transmission | biological process | PTEN, CACNA2D2 |
| riboflavin biosynthetic process | biological process | RFK |
| riboflavin metabolic process | biological process | ENPP1, RFK, SLC52A3, SLC52A2, SLC52A1, FLAD1 |
| riboflavin transport | biological process | SLC52A3, SLC52A2, SLC52A1, ABCG2 |
| ribonucleoprotein complex assembly | biological process | SHQ1, RPL38 |
| ribonucleoprotein complex biogenesis | biological process | TGS1 |
| ribonucleoprotein complex localization | biological process | PRPF31 |
| ribonucleoside diphosphate catabolic process | biological process | NUDT5 |
| ribonucleoside monophosphate biosynthetic process | biological process | PRPS2, PRPS1L1, GART, ADK, PRPS1, ADSL, PFAS |
| ribonucleotide metabolic process | biological process | RNASEH2B, ATIC |
| ribose phosphate biosynthetic process | biological process | G6PD, TKT |
| ribose phosphate metabolic process | biological process | NUDT5, RPIA, PPAT |
| ribosomal large subunit assembly | biological process | RPL3, RPL5, RPL24, RPL6, RPL10L, MRPL20, RSL24D1, RPLP0, BRIX1, RPL11, MRTO4, RPF2, MRPL11, RPL3L, RPL12, MDN1, RPL10, RPL23A, RRS1, NOP2, NLE1, PPAN |
| ribosomal large subunit biogenesis | biological process | RPL5, GTF3A, NPM1, RPL7, RPL11, MRTO4, SURF6, RPL35A, NOP16, WDR12, RPF2, EBNA1BP2, NIP7, RPL14, HEATR3, ZNF622, SDAD1, RPL26L1, WDR74, MALSU1, PAK1IP1, EIF6, RRS1, NVL, NLE1, PES1, RPL26, LTO1, NOC2L |
| ribosomal large subunit export from nucleus | biological process | NPM1, NUP88, XPO1, RAN, SDAD1, RRS1, ZNF593 |
| ribosomal protein import into nucleus | biological process | IPO11, IPO5, RPL23 |
| ribosomal small subunit assembly | biological process | RPS10, RPS14, MRPS11, RPS27L, RPS19, RPS5, ERAL1, MRPS7, RPS27, PWP2, RPS15, RPS28, RPSA, RRP7A |
| ribosomal small subunit biogenesis | biological process | RPS7, RPS6, NPM1, SURF6, NOM1, RPS19, NOP14, RIOK1, NOB1, RPS16, RPS15, RPS24, RPS28, EMG1, RPS17, LTV1, RIOK2, NAT10 |
| ribosomal small subunit export from nucleus | biological process | NPM1, NUP88, XPO1, RPS15, RAN, LTV1 |
| ribosomal subunit export from nucleus | biological process | XPO1, RAN, LSG1, EIF6 |
| ribosome assembly | biological process | MRPL22, NPM1, EIF2A, DHX29, NIP7, DHX37, MTERF4 |
| ribosome biogenesis | biological process | C1QBP, DROSHA, UTP14C, NSA2, PWP1, GTF3A, GTPBP4, RPF1, RSL24D1, DDX3X, DKC1, RPLP0, RPL7A, BRIX1, IMP3, GNL3L, NOP58, XRCC5, MRTO4, SBDS, SURF6, FRG1, WDR75, DCAF13, XPO1, URB2, RIOX2, ERAL1, NOP14, DDX31, NOP10, MRPL10, IMP4, WDR12, NHP2, FASTKD2, GNL2, RPF2, SNU13, EFL1, NOP56, WDR36, EBNA1BP2, RIOK1, UTP4, MTERF3, GLUL, KRR1, UTP23, NIP7, HEATR1, MPHOSPH10, RPS28, PRKDC, EMG1, SDAD1, RRN3, FCF1, RIOK3, BUD23, TSR1, RBIS, MALSU1, NOL11, ZNHIT6, AATF, DHX30, PAK1IP1, MRPL36, TSR3, EIF6, CEBPZ, RRS1, NVL, NOP2, ABCF1, NAF1, GTPBP10, PES1, DHX37, UTP14A, RIOK2, NOC4L, DDX56, RCL1, FTSJ3, MYBBP1A, DDX51, BMS1, DDX27, ISG20L2, GAR1 |
| ribosome disassembly | biological process | DENR, EIF2D, MCTS1, MRRF, PELO, MTIF3, GFM2 |
| ribosome-associated ubiquitin-dependent protein catabolic process | biological process | LTN1, NEMF |
| right lung development | biological process | SHH |
| right lung morphogenesis | biological process | FOXF1 |
| right ventricular cardiac muscle tissue morphogenesis | biological process | ZFPM2, NKX2-5 |
| righting reflex | biological process | ALDH1A3, AFG3L2, FOXP2, GLRA1, SHANK1 |
| ripoptosome assembly involved in necroptotic process | biological process | CYLD |
| RNA (guanine-N7)-methylation | biological process | WDR4 |
| RNA 3' uridylation | biological process | TENT4B, TUT4, TENT4A, TUT7, LIN28A |
| RNA 3'-end processing | biological process | LIN28B, PAPOLA, PAPOLB, PAPOLG, CSTF3, TUT4, TUT7, LIN28A |
| RNA 5'-cap (guanine-N7)-methylation | biological process | RNMT, RAMAC |
| RNA 5'-end processing | biological process | PIWIL2 |
| RNA biosynthetic process | biological process | TERT, MED21, POLR2M |
| RNA catabolic process | biological process | RNASET2, RNASEH2B, SUPV3L1, MTREX, HNRNPD, TTC37, STK31, ISG20, NCBP1, AEN, XRN2, RNASE2, PPP1R8, EXOSC7, EXOSC5, EXOSC8, SIDT2, PNPT1, RNASE6, RNASE3, RNASEH2A, SKIV2L, PABPC4, RNASEH1, SND1, OAS2 |
| RNA destabilization | biological process | TNFRSF1B, DXO |
| RNA export from nucleus | biological process | SRSF4, SRSF9, SRSF6, ZC3H11A, NCBP2, HNRNPA1, SARNP, POM121, THOC3, DDX39B, THOC7, THOC1, NPAP1, CDC40, SLU7, NUP62, CASC3, NCBP1, U2AF1L4, NUP155, NUP153, SRSF3, RBM8A, RAE1, ALYREF, POLDIP3, DDX39A, EIF4E, POM121L2, NXT1, SRSF11, SRSF7, THOC2, NUP133, CHTOP, THOC5, MAGOHB, UPF3B, NXF1, TPR, NUP98, U2AF1, SRSF2, SRRM1, U2AF2, THOC6, EIF4A3, NUP188, NUP214, SRSF5 |
| RNA folding | biological process | WRAP53 |
| RNA import into mitochondrion | biological process | PNPT1 |
| RNA import into nucleus | biological process | TPR |
| RNA interference | biological process | NRDE2 |
| RNA localization | biological process | PRPF6, YY1, IGF2BP1 |
| RNA localization to chromatin | biological process | HNRNPU |
| RNA metabolic process | biological process | RBFOX2, HNRNPF, HNRNPU, HNRNPA0, LSM1, HNRNPM, NCBP2, POLR2F, HNRNPR, DUSP11, HNRNPA1, HNRNPA3, HNRNPC, POLR2G, HNRNPD, GTF2F1, WTAP, HNRNPA2B1, PCBP1, NCBP1, DDX24, XRN2, POLR2B, POLR2D, HNRNPH2, POLR2J, POLR2L, POLR2E, HNRNPH1, TSN, POLR2K, POLR2I, WDR74, GTF2F2, PCBP2, LSM8, POP5, RNASEH2A, POLR2C, POLR2H, HNRNPK, POLR2A, DDX54, ATXN2 |
| RNA methylation | biological process | TRMT2A, NSUN2, RBM15, NSUN6, HENMT1, NSUN5, FTSJ1, NSUN3, MEPCE, TGS1, RBM15B, NOP2, FTSJ3, METTL16, METTL4 |
| RNA modification | biological process | DKC1, PARN, RPUSD4, RPUSD3, TRUB1, PUSL1, PUS10, PUS3, PUS7L, RPUSD1, TRUB2, PUS7 |
| RNA phosphodiester bond hydrolysis | biological process | DROSHA, AZGP1, RNASET2, POP4, RPP14, ZC3H12A, RPP38, RNASE11, RNASE4, HELZ2, RNASE2, PPP1R8, RPP25, RNASEL, PRORP, DIS3, SAMHD1, RNASE6, RNASE3, POP5, RNASEH2A, MRPL44, RPP21, TSEN2, ANG, ERN2, DIS3L2, RNASE7 |
| RNA phosphodiester bond hydrolysis, endonucleolytic | biological process | APEX1, DROSHA, DICER1, RNASET2, POP4, RPP14, LACTB2, FEN1, ZC3H12A, RNASEH2B, RPP38, CPSF3, RNASE4, ENDOV, POP1, AGO3, RNASE2, ENDOG, RPP25, EXO1, RNASEL, SLFN11, DBR1, PRORP, SMG6, NUDT16, NOB1, RIDA, YBEY, ERN1, TSN, KHNYN, EDC3, AGO2, TSNAX, POP5, RNASEH2A, AGO1, MRPL44, RPP21, TSEN2, POP7, ERN2, ZC3H12D, RNASEH1, SND1, EXOG |
| RNA phosphodiester bond hydrolysis, exonucleolytic | biological process | EXOSC10, PAN3, CNOT1, ZC3H12A, CNOT8, PARN, ERI2, ISG20, DCP2, REXO2, TOE1, XRN2, PAN2, ANGEL2, EXOSC5, EXOSC1, XRN1, DIS3, PNPT1, CNOT6L, TRIR, EXOSC4, CNOT2, EXD2, USB1, DIS3L, CNOT3, EXOSC6, DCPS, DIS3L2, ISG20L2 |
| RNA polyadenylation | biological process | PAPOLA, PAPOLB, TENT2, PAPOLG, PNPT1, TENT4B, TENT4A |
| RNA polymerase I preinitiation complex assembly | biological process | SMARCA4, POLR1E, UBTF, TAF1C, TAF1B, SMARCB1, BAZ2A, RRN3 |
| RNA polymerase II core complex assembly | biological process | GTF2B |
| RNA polymerase II transcriptional preinitiation complex assembly | biological process | TAF7L, GTF2A2, TAF12, GTF2B, TAF7, TAF11, MED6, TAF1, TAF6 |
| RNA polymerase III preinitiation complex assembly | biological process | TBPL2, BDP1, BRF2, BRF1 |
| RNA processing | biological process | XAB2, DROSHA, DICER1, HNRNPL, TDRD9, EXOSC10, ADAT1, POP4, HNRNPF, HNRNPU, M1AP, DKC1, RNGTT, ADARB1, SUGP2, TRMT2A, DUSP11, RBMS1, GRSF1, TRNT1, EXOSC9, HNRNPD, SNRNP40, THOC1, WBP11, RTCA, SYNCRIP, SSB, HNRNPH3, ADAR, DEDD2, RTCB, SETX, ZFC3H1, PRPF6, RBM3, SART3, XRN2, CHERP, TRUB1, BICD1, NOL9, UTP6, RNASEL, RBM39, RBM8A, U2SURP, RBMS2, TMTC1, DDX20, ATXN1, SNRPD1, EXOSC1, MPHOSPH10, HNRNPDL, SUGP1, ADAD2, CELF2, ELAVL4, HNRNPH1, EXOSC8, LARP6, NUFIP1, PNPT1, RBM4, CSTF3, SF3A1, DDX17, HNRNPUL1, CCNL1, RBM6, SFSWAP, MRPL44, TRUB2, MRM3, ADARB2, RCL1, HNRNPK, PABPC4, PABPN1, PRPF39, TFIP11, PDCD11, DDX54, RBPMS, APOBEC1, LSM4, PRPF4, NOVA1, CLP1, CRNKL1 |
| RNA repair | biological process | ALKBH1 |
| RNA secondary structure unwinding | biological process | DDX3Y, DDX4, DDX25, DDX3X, DHX36, AGO4, DDX39B, AGO3, AGO2, AGO1 |
| RNA splicing | biological process | WT1, SNRPN, BRDT, PABPC1, C1QBP, XAB2, RBMY1A1, SRSF4, SRSF9, SRSF6, RBMX, TCERG1, RBFOX2, ZRANB2, HSPA8, FUS, HNRNPF, HNRNPU, IK, FAM172A, PPIL3, LSM1, PLRG1, HNRNPM, NCBP2, LSM3, ZNF638, CIR1, SUGP2, CTNNBL1, DDX47, CWC15, HNRNPR, SF3B1, HNRNPA1, HNRNPA3, PPP2CA, TXNL4A, VIRMA, DDX46, SRSF12, THOC3, YTHDC1, SRSF8, RBM22, PRPF19, STRAP, IVNS1ABP, HNRNPC, SFPQ, MTREX, RBM25, MFAP1, RBM10, DDX39B, FRG1, SNRNP35, THOC7, SNIP1, SNRNP40, THOC1, PPP1R9B, SCAF1, TTF2, SRRM2, WBP11, SYNCRIP, CDC40, SNRPB2, HNRNPH3, WTAP, ARL6IP4, ESRP1, PRPF18, DDX23, SNRNP25, SAP18, SLU7, HNRNPA2B1, BUD31, ZC3H13, RBM4B, CWC25, CASC3, PRPF6, TRA2B, NCBP1, SART3, PHF5A, KHDC4, ZCRB1, U2AF1L4, PRPF31, SRPK1, PPARGC1A, LUC7L3, YBX1, SRPK2, RP9, IWS1, ACIN1, ECD, SYF2, SNU13, SNRPE, PPP1R8, SF3B2, TRA2A, MBNL1, RBM28, DHX15, SRSF3, RBM39, NONO, PRPF38A, SNRNP27, GEMIN6, ZNF830, MBNL3, RBM8A, WBP4, CCDC130, SNRPB, DDX41, CD2BP2, AFF2, ALYREF, GEMIN5, DDX20, DDX39A, AQR, PRPF40A, GEMIN4, SNRPD1, CDK13, TAF15, RSRC1, CELF4, SF3B6, MPHOSPH |
| RNA splicing, via transesterification reactions | biological process | SRSF4, LSM1, SF3B1, TXNL4A, SNRNP40, DDX23, SLU7, PRPF6, TRA2B, DBR1, MPHOSPH10, PRPF3, BCAS2, PRPF8, SCAF11, SF3B3, SF3B4, SF3A3, SMNDC1, SRRM1, WDR83, KHSRP, PRPF4 |
| RNA stabilization | biological process | TENT2, NAF1 |
| RNA surveillance | biological process | PELO |
| RNA transport | biological process | NXF2, RTRAF, HNRNPA2B1, YBX1, SIDT2, RBFOX1, CKAP5, SIDT1, ATXN2 |
| RNA-dependent DNA biosynthetic process | biological process | TERT, TEP1, PPIA |
| rod bipolar cell differentiation | biological process | PTN |
| roof plate formation | biological process | GDF7 |
| rostrocaudal neural tube patterning | biological process | ATP6AP2 |
| Roundabout signaling pathway | biological process | MYO9B, SLIT3, SLIT2, ROBO1 |
| rRNA (guanine-N7)-methylation | biological process | BUD23 |
| rRNA 2'-O-methylation | biological process | MRM3 |
| rRNA 3'-end processing | biological process | ERI1 |
| rRNA acetylation involved in maturation of SSU-rRNA | biological process | NAT10 |
| rRNA base methylation | biological process | NSUN5, METTL15, EMG1, NOP2, METTL16 |
| rRNA catabolic process | biological process | DROSHA, EXOSC9, DEDD2, EXOSC7, EXOSC5, SLFN11, XRN1, EXOSC8, DIS3, TRIR, EXOSC4, DIS3L, EXOSC6, ERN2 |
| rRNA export from nucleus | biological process | NPM1, TSC1 |
| rRNA import into mitochondrion | biological process | TST, PNPT1 |
| rRNA metabolic process | biological process | NIFK, NAT10 |
| rRNA methylation | biological process | TFB2M, DIMT1, METTL5, NSUN3, FBL, BUD23, TRMT61B, BMT2, TFB1M, RRNAD1, MTERF4, FTSJ3 |
| rRNA modification | biological process | TFB2M, DIMT1, THUMPD1, TFB1M, TSR3, RRNAD1, NAT10 |
| rRNA processing | biological process | CDKN2A, CHD7, EXOSC10, UTP14C, NSA2, POP4, RPL5, RPL27, RPS7, RPS14, RPS6, RPF1, DKC1, DDX47, IMP3, NOP58, RPL7, RPL11, TFB2M, TEX10, MRTO4, SBDS, RPL35A, MTREX, RPS9, RPP38, EXOSC9, FRG1, WDR75, DCAF13, DIMT1, WBP11, UTP11, RRP15, RPS2, RPS19, ISG20, NOP14, DDX10, NOP10, DDX21, LYAR, DDX52, RPS27, IMP4, WDR12, XRN2, NHP2, MPHOSPH6, REXO4, ESF1, SNU13, EXOSC7, NOL9, NOL8, PELP1, NSUN5, RPP25, EXOSC5, UTP6, NOP56, RNASEL, PWP2, WDR36, EBNA1BP2, ERI1, UTP4, KRR1, UTP23, UTP3, NOB1, GEMIN4, RPS16, RPS15, RRP12, HEATR1, EXOSC1, MPHOSPH10, RPL14, YBEY, RPS24, RPS28, SENP3, EXOSC3, MDN1, DDX49, FBL, C1D, EMG1, EXOSC8, WDR18, WDR55, DIS3, FCF1, BUD23, UTP20, RPS17, WDR74, PIH1D2, NOL11, EXOSC4, PIN4, UTP18, LSM6, TENT4B, TFB1M, DDX17, TSR3, POP5, NVL, NPM3, NOP2, NAF1, TSR2, PES1, RPL26, RRP1B, DHX37, UTP14A, MRM3, EXOSC6, DIEXF, NOC4L, DDX56, RCL1, POP7, TBL3, EXOSC2, MTERF4, FTSJ3, DDX51, RRP7A, EIF4A3, PDCD11, DDX54, NAT10, BMS1, RBFA, DDX27, NOL6, ISG20L2, GAR1 |
| rRNA pseudouridine synthesis | biological process | DKC1, NOP10, NHP2, GAR1 |
| rRNA transcription | biological process | GTF3A, POLR1B, MARS1, NIFK, SIRT7, NPM3, GTF3C1, ANG, CAVIN1, BRF1, TP53 |
| rRNA transport | biological process | TST |
| ruffle assembly | biological process | AIF1, MTSS2, SNX10, BAG4, CSPG4, AIF1L, PIP5K1A, DBNL, RAC1, INPP5K, ARF6, PDGFRB, ARHGEF26 |
| ruffle organization | biological process | MTOR, TPM1, CORO1B, PLEKHA1, PLEK, LIMA1, RAC1, CYFIP1, CARMIL1, CCR7, TCIRG1, CSF1R, CCL21 |
| S-adenosyl-L-methionine transmembrane transport | biological process | SLC25A26 |
| S-adenosyl-L-methionine transport | biological process | SLC25A26 |
| S-adenosylhomocysteine catabolic process | biological process | AHCY |
| S-adenosylhomocysteine metabolic process | biological process | DNMT1, DNMT3B, GAMT, GNMT, PEMT |
| S-adenosylmethioninamine biosynthetic process | biological process | AMD1 |
| S-adenosylmethioninamine metabolic process | biological process | DNMT1, DNMT3B |
| S-adenosylmethionine biosynthetic process | biological process | MAT2B, MAT2A, MAT1A, METTL16 |
| S-adenosylmethionine cycle | biological process | MTRR, AHCYL1, AHCY, AHCYL2 |
| S-adenosylmethionine metabolic process | biological process | DNMT1, MTHFR, GAMT, GNMT, AMD1, PEMT, BHMT2 |
| S-methylmethionine metabolic process | biological process | BHMT2 |
| S-shaped body morphogenesis | biological process | HES1, PAX8, LHX1 |
| SA node cell action potential | biological process | ANK2, CACNA1G, GJA5, HCN4, SCN5A, SCN3B |
| SA node cell to atrial cardiac muscle cell communication | biological process | ANK2 |
| SA node cell to atrial cardiac muscle cell communication by electrical coupling | biological process | GJA5, GJC1 |
| SA node cell to atrial cardiac muscle cell signaling | biological process | CACNA1G |
| sagittal suture morphogenesis | biological process | GLI3 |
| saliva secretion | biological process | AQP5, KCNN4, STATH, CHRM3, CHRM1 |
| salivary gland cavitation | biological process | SHH, NFIB, TGM2, EDA, EDAR |
| salivary gland development | biological process | NKX3-1, TFCP2L1, FGF10 |
| salivary gland morphogenesis | biological process | EGFR, TGFB1, TGFB3, FGFR1, BMP7, TGFB2, TWSG1, POLB, FGF10 |
| sarcomere organization | biological process | ITGB1, TPM1, TCAP, MYOM2, WDR1, CASQ2, CAPN3, CFL2, MYOM3, KLHL41, ACTN2, TTN, MYPN, CSRP3, KRT19, ACTG1, OBSCN, CSRP1, LDB3, SIX4, CAPN9, SRF, KRT8, FHOD3, TNNT1, NKX2-5, MYH3, MYH6, LMOD2, CASQ1, TNNT3, MYOM1, MYLK3, ANKRD1, MYOZ1, MYOZ2 |
| sarcomerogenesis | biological process | TCAP, TTN, MYLK3 |
| sarcoplasmic reticulum calcium ion transport | biological process | ATP2A2, RYR2, SLN, ANK2, CACNG1 |
| sarcosine catabolic process | biological process | SARDH |
| sarcosine metabolic process | biological process | GNMT |
| satellite cell activation involved in skeletal muscle regeneration | biological process | KLF5 |
| saturated monocarboxylic acid metabolic process | biological process | ACOT4 |
| scaRNA localization to Cajal body | biological process | CCT4, DKC1, CCT2, TCP1, WRAP53 |
| SCF complex assembly | biological process | SKP1, CUL1, CAND1, RBX1, CAND2, FBXL7 |
| SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | biological process | PSMB1, PSMB5, PSMC2, FBXO38, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, FBXL5, PSMD14, PSMD7, FBXL22, FBXW7, FBXO17, FBXL12, BTRC, PSMB6, FBXL13, FBXO9, PSMD10, PSMD8, PSMC5, KIF14, FBXO2, PSMB4, PSME1, CUL1, PSMB8, PSMD4, FBXO33, FBXO4, PSMC3, PSMA6, FBXL4, FBXL16, CUL5, FBXO39, DMAC2, FBXL17, FBXL3, SKP2, PSMD12, PSMB9, PSMC4, CUL2, PSMD9, PSMA4, PSMD2, AMN1, FBXO6, PSMD5, PSMF1, PSMB3, FBXL6, CCNF, PSMD3, PSMC1, RBX1, WWTR1, FBXW5, FBXO44, FBXL2, FBXL7, FBXO31, FBXL14, LRRC29, FBXL20, PSMD13, PSMB10 |
| Schwann cell development | biological process | POU3F2, ILK, MED12, CDK5, DAG1, LGI4, NF1 |
| Schwann cell differentiation | biological process | NAB1, EGR2, ADAM22, ERBB3, DAG1, GPC1, NAB2 |
| Schwann cell proliferation | biological process | CTNNB1, NF2 |
| sclerotome development | biological process | PAX1, SFRP2 |
| sebaceous gland cell differentiation | biological process | FA2H |
| sebaceous gland development | biological process | SMAD4, WNT10A, ZDHHC21, RBPJ, ASH1L, ACER1 |
| sebum secreting cell proliferation | biological process | PRDM1 |
| second-messenger-mediated signaling | biological process | PPP2CA, PPP2R1A, TBXA2R, DGKD |
| secondary heart field specification | biological process | BMP4, ISL1, SMARCD3, MEF2C, LRP2, RBPJ, WNT11, AXIN2, MESP1, FOXH1 |
| secondary metabolite biosynthetic process | biological process | CYP11A1, CYP11B1, CYP11B2 |
| secondary palate development | biological process | SMAD4, WNT3A, TGFB2, LRRC32, SMAD2, LEF1, WNT11, TGFBR2, WNT7A |
| secretion | biological process | CA2, RIMS1, CA9, FBLN5, PTGES2, TPD52 |
| secretion by cell | biological process | AXL, USE1, ABCA12, CKLF, PCSK6, FURIN, MERTK, TYRO3 |
| secretion by lung epithelial cell involved in lung growth | biological process | TMEM38B, FGF7, FGF10 |
| secretion of lysosomal enzymes | biological process | M6PR, NAGPA |
| secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development | biological process | WDR77, FOXA1, NOTCH1 |
| secretory granule localization | biological process | USO1, RASGRP1, MYO5A, PIK3CG |
| secretory granule organization | biological process | SRGN |
| segment specification | biological process | HOXA2, MSGN1, MLLT3, BMI1, DVL2, MTF2 |
| segmentation | biological process | PSEN1, DVL2 |
| selective autophagy | biological process | SQSTM1 |
| selenium compound metabolic process | biological process | TXNRD1, SEPHS2, SELENOP, SCLY, MAT1A |
| selenocysteine biosynthetic process | biological process | SEPHS1, SEPHS2 |
| selenocysteine incorporation | biological process | SELENOT, SEPSECS, TRNAU1AP, SECISBP2L, DIO2, SECISBP2, EEFSEC |
| selenocysteine metabolic process | biological process | SEPHS2, SEPSECS, SARS1 |
| selenocysteinyl-tRNA(Sec) biosynthetic process | biological process | SARS2, SEPSECS, SARS1, PSTK |
| self proteolysis | biological process | LGMN, CAPN3, CAPN7, ADGRV1, CAPN1, TMPRSS6 |
| semaphorin-plexin signaling pathway | biological process | SEMA7A, SEMA3A, ARHGDIA, SEMA3E, SEMA6D, SEMA3F, PLXNC1, SEMA4C, SEMA3G, SEMA4G, SEMA4D, RAC1, PLXNA1, SEMA6A, PLXNA4, FARP2, SEMA3B, SEMA3C, SEMA6C, PLXNB3, SEMA6B, NRP1, PLXNA3, PLXNB2, PLXNB1, PLXNA2, SH3BP1, PLXND1, SEMA4B, SEMA5A |
| semaphorin-plexin signaling pathway involved in axon guidance | biological process | SEMA3A, SEMA3F, PLXNC1, PLXNA1, PLXNA4, PLXNB3, NRP1, PLXNA3, PLXNB2, PLXNB1, PLXNA2, PLXND1 |
| semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis | biological process | SEMA4D, PLXNB1 |
| semaphorin-plexin signaling pathway involved in neuron projection guidance | biological process | SEMA3A, SEMA3F, NRP2, NRP1 |
| semicircular canal development | biological process | GATA2 |
| semicircular canal fusion | biological process | FGF10 |
| semicircular canal morphogenesis | biological process | CHD7, ZEB1, EYA1, NR4A3, FGF10 |
| seminal vesicle morphogenesis | biological process | ID4 |
| seminiferous tubule development | biological process | REC8, SMAD4, ATRX, ING2, TBC1D20, KIF18A, WDR48, BRIP1, UBB |
| senescence-associated heterochromatin focus assembly | biological process | CDKN2A, HMGA2 |
| sensitization | biological process | DRD1 |
| sensory neuron axon guidance | biological process | NRP2, GBX1, NRP1 |
| sensory organ boundary specification | biological process | NTF4 |
| sensory organ development | biological process | SOX3, ASCL2, ASCL1, MYO7A, MYO7B |
| sensory perception | biological process | TRPV2, PDYN, NXNL2, NTSR2, OPRL1, MYO7A, ADORA2A, ASIC3, SCN10A, OPRK1, PENK |
| sensory perception of bitter taste | biological process | PLCB2, TAS2R60, ITPR3, CALHM1 |
| sensory perception of chemical stimulus | biological process | GNAS, OR10J1, GNAL, OBP2A, TAAR5, C5AR1 |
| sensory perception of light stimulus | biological process | USH1G, PDE6D, USH2A, USH1C, ADGRV1, GRM6, MYO7A, WHRN, RHO, CDH23, PCDH15 |
| sensory perception of mechanical stimulus | biological process | IFNG, TRPV1 |
| sensory perception of pain | biological process | PTGS1, PTGS2, MAPK3, MAPK1, EDNRA, PROK2, KCNK4, NTRK1, TAC1, IAPP, NDN, GRIN1, RETREG1, NLGN2, KCND2, TRPA1, NMU, HOXD1, EDNRB, CNR1, MECP2, MRGPRX2, NPY1R, P2RX7, NIPSNAP1, ALOXE3, PRDM12, P2RY1, POMK, MME, EDN1, KCNA2, CDK5, HOXB8, GRIN2A, P2RX4, CHRNB2, CHRNA4, OPRL1, DLG2, SCN10A, OPRK1, BDKRB1, MC1R, SCN3B, PENK, UCHL1, CCL2, GRM1, TRPV1 |
| sensory perception of smell | biological process | GNAS, OR2W3, CFAP69, OR12D2, OR2AG2, OR10AD1, OR5AR1, OR52D1, OR5V1, OR9A4, OR51A7, NCAM2, OR1G1, CNGA2, SLC24A4, OR9Q2, OR51V1, OR52A1, OR1L6, MKKS, FZD2, OR1N2, OR6B3, OR10J1, OR1D5, OR10A3, OR2T33, OR52E4, OR2H1, OR2J2, OR56A4, OR10Q1, OR13C4, OR2T4, OR4X1, OR5P2, OR2M4, OR4C12, BBS4, OR5B21, OR5F1, OR5I1, NAV2, OR2L13, OR4D11, OR8D4, OR13A1, OR13C8, OR5R1, OR5K1, OR52B2, UBR3, OR51B6, OBP2A, OR51B5, OR2S2, OR7C2, OR3A1, OR10A4, OR2A4, OR1E1, OR2W1, OR10H1, OR7C1, NXNL2, CNGB1, OR2A14, OR10A5, OR51I2, GJB4, OR10H2, DRD2, OMP, OR5C1, OBP2B, OR2T1, SLC6A3, OR1C1, BBS1, UGT2A1, OR8G1, SYT10, OR9Q1, OR1F1, OR2Z1, OR2T6, OR5AC2, OR6C68, PDE4A, OR4K17, OR5T2, OR5P3, OR8D2 |
| sensory perception of sound | biological process | SOD1, ICAM1, STRC, CASP3, GPX1, HEXB, FGFR1, THRB, CHD7, WFS1, MYO15A, SLC26A4, COL11A1, ATP6V1B1, ROR1, USH1G, NDUFB9, GET1, FBXO11, ASIC2, GSDME, MYH14, FZD4, TIMM9, SERPINB6, RPL38, CEMIP, OTOR, SLC9A3R1, WDR1, CNTN5, COL11A2, USH2A, COL2A1, PSAP, CCDC50, MYO3B, HOMER2, ZNF354A, GABRB3, SLC1A3, DCDC2, USH1C, DIAPH1, GABRA5, CDKN2D, SLC26A5, USP53, PGAP1, NAV2, OTOF, UCN, MYO6, TIMM13, TFAP2A, GABRB2, COL4A3, ESPN, LRP2, PJVK, NIPBL, LHFPL4, SLITRK6, PPIP5K2, TECTA, MBP, CDKN1B, EYA4, LOXHD1, ADGRV1, TMPRSS3, CLIC5, TIMM8B, LRTOMT, TRIOBP, TBL1X, EML2, SIX1, ATP6V0A4, SPRY2, POU3F4, POU4F2, GRAP, TPRN, MYO3A, SLC52A3, TH, TIMM10, EYA1, LRIG2, KCNE1, GJB6, KCNQ4, CACNA1D, TMC1, CHRNB2, LHFPL5, ATP8B1, ATP2B2, MYO7A, MYO7B, ESPNL, TMIE, TSPEAR, CABP2, WHRN, CDH23, SPTBN4, PDZD7, P2RX2, SOBP, TUB, GRM7, COCH, CEACAM16, PCDH15, RIPOR2, SRRM4, OTOA, LRIG1 |
| sensory perception of sour taste | biological process | ASIC1, ASIC2, PKD2L1, ASIC3 |
| sensory perception of sweet taste | biological process | TAS1R2, ITPR3, CALHM1, TAS1R3 |
| sensory perception of taste | biological process | TAS2R38, LCN1, TAS2R9, TAS2R19, TAS1R2, GNB1, TAS2R50, TAS2R60, TAS2R8, SCNN1G, SCNN1A, LEF1, SCNN1D, CALHM1, WNT10B, TAS2R1, GNG13, P2RX3, TRPM5, SCNN1B, TAS1R3, TAS1R1, P2RX2, CD36, TAS2R39 |
| sensory perception of temperature stimulus | biological process | KCNK4, TRPM3, BTBD9 |
| sensory perception of touch | biological process | P2RX4 |
| sensory perception of umami taste | biological process | ITPR3, CALHM1, TAS1R3, TAS1R1 |
| sensory processing | biological process | TTC8, BBS4, CHRNA7 |
| sensory system development | biological process | SEMA3A, ISL1, POU4F1 |
| septin cytoskeleton organization | biological process | LRCH3, RTKN |
| septin ring assembly | biological process | ANLN |
| septin ring organization | biological process | ANLN, RTKN |
| septum primum development | biological process | GJA5 |
| septum secundum development | biological process | NKX2-5 |
| sequestering of actin monomers | biological process | TWF1, SCIN, TMSB15A, TMSB15B, TMSB4Y, TMSB10, TWF2 |
| sequestering of BMP from receptor via BMP binding | biological process | GREM2, NBL1, GREM1 |
| sequestering of BMP in extracellular matrix | biological process | CER1, FBN1, DAND5, NBL1 |
| sequestering of calcium ion | biological process | HSP90B1, CASQ2, ATP7B, CALR |
| sequestering of extracellular ligand from receptor | biological process | CD46 |
| sequestering of metal ion | biological process | S100A7 |
| sequestering of neurotransmitter | biological process | SLC18A2, SLC17A7 |
| sequestering of nodal from receptor via nodal binding | biological process | DAND5 |
| sequestering of TGFbeta in extracellular matrix | biological process | LTBP1, FBN2, FBN1, NRROS |
| sequestering of triglyceride | biological process | TNF, IL1B, ENPP1 |
| sequestering of zinc ion | biological process | S100A9, SLC30A8, SLC30A7, S100A8 |
| serine family amino acid biosynthetic process | biological process | MTHFD1 |
| serine family amino acid catabolic process | biological process | THNSL2 |
| serine family amino acid metabolic process | biological process | MTHFD1, SRR |
| serine import into mitochondrion | biological process | SFXN1, SFXN3, SFXN2 |
| serine phosphorylation of STAT protein | biological process | CDK5R1, NLK, CDK5, IL24 |
| serine transport | biological process | SLC38A5 |
| serotonergic neuron axon guidance | biological process | FZD3, VANGL2, CELSR3 |
| serotonin biosynthetic process | biological process | DDC, TPH1, TPH2 |
| serotonin metabolic process | biological process | SRD5A1, PDE1B, ATP7A, GRIN2A, BTBD9 |
| serotonin receptor signaling pathway | biological process | HTR3B, HTR3A, HTR3E, HTR2C, HTR2B |
| serotonin secretion | biological process | SYK |
| serotonin secretion by platelet | biological process | SYK, FCER1G |
| serotonin transport | biological process | SLC6A4 |
| serotonin uptake | biological process | SLC22A2, SLC6A4, SLC18A2, SLC22A1, SLC22A3 |
| Sertoli cell development | biological process | ESR1, SOX9, HSD17B4, ESR2, DMRT1, NTRK1, ATRX, NUP210L, SDC1, FNDC3A |
| Sertoli cell differentiation | biological process | SOX9, NR0B1, DMRT1, CTSV, SAFB2 |
| Sertoli cell fate commitment | biological process | RARA |
| Sertoli cell proliferation | biological process | FSHB, ESR1, BAX, ESR2, BCL2L2, ACVR2A |
| seryl-tRNA aminoacylation | biological process | SARS2, SARS1 |
| sesquiterpenoid metabolic process | biological process | ALDH3A2 |
| sex determination | biological process | AMH, WT1, SOX3, NR0B1, SRY, SRD5A1, CITED2 |
| sex differentiation | biological process | AMH, AR, SRD5A2, BAX, AMHR2, CYP17A1, SRY, DMRT1, SRD5A1, DMRT2, TSPY1, CBX2, Dmrtc2, STAT5B, CENPI, WNT4, CNTFR, CNOT9, PBX1, DMRT3, HNF4A, CDKL2, WNT7A |
| sexual reproduction | biological process | HEXB, TNP1, STAT3, LEP, LEPR, SELENOP, VGF, EIF4H |
| short-chain fatty acid biosynthetic process | biological process | OXSM |
| short-chain fatty acid catabolic process | biological process | PCCA, MCEE, PCCB, MMAA |
| short-chain fatty acid import | biological process | SLC5A8, SLC22A9 |
| short-chain fatty acid metabolic process | biological process | CRAT, ACOT4 |
| short-chain fatty acid transport | biological process | CD36 |
| short-term memory | biological process | COMT, ADNP, CALB1, MDK, CHRNA7, CUX2, PTCHD1, SLC2A4, SERPINF1, BRINP1, NPAS4 |
| short-term synaptic potentiation | biological process | SYT7 |
| sialic acid transport | biological process | SLC17A5 |
| sialylation | biological process | ST6GALNAC6, ST6GAL1, ST6GALNAC4, ST8SIA2, ST8SIA4, ST6GAL2, ST8SIA1, ST3GAL4, ST6GALNAC5, ST6GALNAC1, ST3GAL6, ST8SIA5, ST3GAL1, ST3GAL2, ST6GALNAC3 |
| siderophore biosynthetic process | biological process | BDH2 |
| siderophore transport | biological process | SLC22A17 |
| signal clustering | biological process | SEMA5A |
| signal complex assembly | biological process | SRC, PXN, NCK1, PTK2, NCK2, CD3E, MAPK8IP2, PTK2B |
| signal peptide processing | biological process | F10, BGLAP, GAS6, SEC11A, SEC11C, SPCS3, SPCS1, SPCS2, HM13, IMMP2L, SPPL3, FURIN |
| signal transduction | biological process | EGFR, EGF, CGA, FSHB, LHB, IL1B, ESR1, PGR, CXCL8, AR, VDR, TNFRSF1A, KITLG, LHCGR, FSHR, FAS, CASP1, ADM, IGFALS, IL6ST, SOX9, TNFSF10, GNAS, HIF1A, AMHR2, NOSTRIN, RXFP2, ESR2, NDRG2, NR1I2, ERBB2, HSP90AA1, MAPK1, AXL, AKT1, STAT1, KIR2DS2, FASLG, ATM, GAS6, STAT4, TLR4, GNRH2, TLR2, C3, GNRH1, NR3C1, GNAO1, TRH, EDNRA, GNRHR, STAT3, LEP, MTOR, PGF, GNAI1, CSNK2B, PLAUR, AKAP4, IGSF1, GDF15, IL1RAPL1, IGF1, IGF1R, KIT, IGF2R, SRC, FPR1, PDIA3, CHKA, CD69, KHDRBS1, PDCD1, GPRC6A, PROKR2, KISS1R, IL21, NPHP1, FGF17, PLAU, RAF1, GJA1, NR2F2, F2R, TACR3, OXTR, PPARG, CCR5, TAS2R38, RAP1A, SOS1, LGALS3BP, OR2W3, PLCZ1, IL17RD, CLOCK, NPHP4, OXT, INHA, FGF3, ANK1, FGF9, RANGAP1, CREM, CAMK4, ECM1, RASSF1, MAS1, S100A9, ANXA5, ANXA4, FST, S100A11, GDNF, MAPK14, TNFRSF25, CCN1, INPP4B, PSTPIP1, PLCH2, DIRAS3, IAPP, AREG, GABRB1, RASA1, CCN2, RYK, HINT1, P2RY4, OR12D2, FGF12, CCL20, BEX3, PDE4C, PPFIA1, CAMK2B, DGKK, VN1R2, RIN2, OPTN, ERBIN, LPAR4, ACKR4, SIGLEC8, GPR160, RAB21, MOK, OR2AG2, SIRPB1, JAK2, LPXN, TN |
| signal transduction by p53 class mediator | biological process | MAGEA2, CDKN1A, GREM1, TP53 |
| signal transduction by protein phosphorylation | biological process | AMHR2, KDR, INSR, BMPR2, CAB39, STK3, MAP3K4, MAP4K2, NEK1, STK4, MAP4K1, STK25, STRADB, MAP3K8, TAOK2, STK10, ROS1, MAP4K3, MAP4K4, MAP2K4, MAP2K3, TAOK3, MAP2K7, PAK6, CLEC1B, MAP3K3, MAP2K2, STRADA, TNIK, MAP3K19, SLK, STK26, NEK4, TAOK1, MAP3K2, MAP2K6, MAP2K1, MAP3K14, PAK3, OXSR1, PAK4, MAP2K5, PAK5, MINK1, MAP3K1 |
| signal transduction by trans-phosphorylation | biological process | WNK1, OXSR1 |
| signal transduction downstream of smoothened | biological process | IFT122 |
| signal transduction in response to DNA damage | biological process | CASP9, MAPK14, ATAD5, GADD45A, BID, GRB2, CEP63, ABL1 |
| signal transduction involved in cell cycle checkpoint | biological process | SOX11 |
| signal transduction involved in DNA damage checkpoint | biological process | PRPF19, TREX1, CDC5L |
| signal transduction involved in G2 DNA damage checkpoint | biological process | UIMC1, FZR1, DTL, BABAM1, BABAM2, ABRAXAS1, PLK1, CDC14B |
| signal transduction involved in mitotic G1 DNA damage checkpoint | biological process | PRKDC |
| signal transduction involved in mitotic G2 DNA damage checkpoint | biological process | ATM |
| signal transduction involved in regulation of gene expression | biological process | PARP1, FGF8, EPCAM, CER1, MSX1, FGF5, NEUROD1, SMAD2, HNF4A, P2RY1, GSC, MSX2, DAND5, PDGFRA, MESP1, TBX6, SMAD3 |
| signaling | biological process | CCR5, DLGAP5, CCL3, DLGAP1, DLGAP4, APPL2, APPL1 |
| single fertilization | biological process | DAZ2, HEXB, AKAP4, PARK7, BPY2, SERPINA5, ACR, CD46, IZUMO1, CD9, BSPH1, PLCZ1, DEFB126, SPAG1, SPA17, GLIPR1L1, LHFPL2, KDM5B, SMAD4, TRPC3, LYZL6, TARBP2, OR10J1, SNU13, MFGE8, GNPDA1, TUBGCP3, TRPC7, HYAL3, SLC22A16, ADAM2, WDR48, HOXD10, ASH1L, MST1R, IGSF8, CCDC87, UBXN8, HOXA11, OVGP1, HOXA9, FOXL2, IRAG2, ASTL, UMODL1, CRKL, H3-3A, FETUB, ZP3, HOXA10, CCDC136 |
| single organismal cell-cell adhesion | biological process | EGFR, ICAM1, BCL2, CD44, SOX9, CTNNB1, SRC, NPHP1, CDH1, CDC42, NPHP4, CRISP2, PKD1 |
| single strand break repair | biological process | LIG4, XRCC1, TNP1, APTX, ERCC6, ERCC8, TDP1, APLF |
| single stranded viral RNA replication via double stranded DNA intermediate | biological process | SMARCB1 |
| sinoatrial node cell development | biological process | BVES, TBX3 |
| sinoatrial node cell differentiation | biological process | MESP1 |
| sinoatrial valve morphogenesis | biological process | MEF2C |
| sinus venosus morphogenesis | biological process | MESP1 |
| siRNA loading onto RISC involved in RNA interference | biological process | DICER1, TARBP2, AGO2, CLP1 |
| sister chromatid biorientation | biological process | RB1 |
| sister chromatid cohesion | biological process | BIRC5, REC8, CDC20, RANGAP1, RAD51C, FBXW7, SMC3, SMC5, HDAC8, PHB2, MRE11, PLK1, RAD21, ESCO1, STAG2, STAG1, SMC1A, TENT4A, MCMBP, DDX11, KIF22 |
| sister chromatid segregation | biological process | TOP2A, LATS1, TOP2B |
| site-specific DNA replication termination at RTS1 barrier | biological process | RTF2 |
| skeletal muscle acetylcholine-gated channel clustering | biological process | ETV5, FNTA, DVL1, RER1, LRP4 |
| skeletal muscle atrophy | biological process | IL15, PPARGC1A, CFLAR, MSTN, MYOG, ACTN3 |
| skeletal muscle cell differentiation | biological process | ATF3, PLAGL1, RB1, EMD, HIVEP3, PHOX2B, BCL9, EOMES, ANKRD2, EGR1, LEMD2, NUPR1, EEF2, NOTCH1, WNT3A, COPS2, MEF2C, HMG20B, KLHL41, HLF, MAFF, BTG2, SAP30, SOX11, PAX5, ZNF689, EGR2, MEF2D, BCL9L, FOXN2, KLF5, FOS, MYOD1, MYOG, ANKRD33, SMYD1, MYLK2, GTF3C5, ANKRD1 |
| skeletal muscle contraction | biological process | MYH7, HSP90AA1, ATP2A2, TCAP, MYH14, RCSD1, EEF2, CHRNB1, CHRND, HOMER1, TNNI2, STAC2, TNNT1, STAC3, JSRP1, MYH3, CCDC78, MYH8, TNNT3, CHRNA1, TNNI1 |
| skeletal muscle fiber adaptation | biological process | MYOD1, MYOZ1, MYOZ2 |
| skeletal muscle fiber development | biological process | GPX1, RYR1, SKI, KLHL41, CAV2, SMO, SELENON, PPP3CA, HOMER1, SIX1, KEL, WNT10B, MYOD1, MYOG, KLHL40, STAC3, MYORG, DNER, BIN3, P2RX2, RIPOR2 |
| skeletal muscle fiber differentiation | biological process | SIX4, KLHL40 |
| skeletal muscle hypertrophy | biological process | MYOC |
| skeletal muscle myosin thick filament assembly | biological process | TCAP, MYOM2, MYH11, MYOM3, TTN, MYOM1 |
| skeletal muscle organ development | biological process | LARGE1, CNTFR |
| skeletal muscle satellite cell activation | biological process | MEGF10, EPHB1, WNT7A |
| skeletal muscle satellite cell commitment | biological process | PAX7 |
| skeletal muscle satellite cell differentiation | biological process | MEGF10, CDON, KLF5, MYLK2 |
| skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration | biological process | EZH2, IGF1, FZD7, WNT7A |
| skeletal muscle satellite cell migration | biological process | RHOC |
| skeletal muscle satellite cell proliferation | biological process | MEGF10 |
| skeletal muscle thin filament assembly | biological process | TCAP, MYOM2, ACTC1, MYOM3, TTN, PROX1, MYOM1 |
| skeletal muscle tissue development | biological process | DCN, NR2F2, MAPK14, SKIL, KCNAB1, PAX7, MYL6, SVIL, METTL21C, MYH14, BVES, FLNB, NEURL1, POPDC3, CFL2, MEF2C, CFLAR, EP300, CSRP3, GPCPD1, FOXP2, ZBTB18, POPDC2, HOXD10, SIX1, SIX4, MYL6B, MYOD1, MYOG, CDK5, HLX, IGSF8, ELN, SRPK3, VAMP5, MEOX2, COL19A1, NPHS1, CASQ1, NF1, MYOZ1, MYOZ2, CAV1 |
| skeletal muscle tissue growth | biological process | CHRND, DLL1, CHRNA1 |
| skeletal muscle tissue regeneration | biological process | GPX1, PLAU, GJA1, NACA, PAX7, PKM, TARBP2, LARGE1, CFLAR, PPP3CA, IFRD1, KLF5, SOX15, ENO3, WNT10B, MSTN, MYOG, DAG1, DYSF, MYMK, SGCA, BIN3, EYS |
| skeletal myofibril assembly | biological process | CFLAR |
| skeletal system development | biological process | VDR, MMP9, SOX9, GNAS, USP1, IGF2, BGLAP, FGFR3, HEXB, FGFR1, BMP7, CTNNB1, IGF1, BMP4, CHD7, INHA, PRDX1, TP63, SHOX, HOXD13, HDAC4, LECT2, COL5A2, SERP1, EXT1, TNFRSF11B, ACP2, HOXA5, FBN1, RPL38, PTH1R, BPNT2, COL3A1, COL11A2, WDR5, NKX3-2, EXTL1, FRZB, BCAN, COL2A1, ACVR2B, EBP, UFD1, GDF11, ANKH, CNMD, ACAN, PRELP, PHEX, HAPLN4, FAM20C, BMP1, NPR3, HOXA13, HES7, SMPD3, SOX11, MMP16, COL1A2, HAPLN1, BMP5, RASSF2, TGFB2, HOXC10, GNA11, MMP14, IFT80, SUFU, DLX6, FOXC2, TRPS1, PAX1, TGFBR1, TLL1, PAPSS2, TRAPPC2, HOXD10, SOX4, ASH1L, TBX3, HOXB4, BMP6, TCOF1, RAI1, HAPLN3, ALX4, GJA5, DLX5, EN1, RUNX2, WFIKKN2, HAPLN2, CHRD, HOXC11, PTHLH, EPHA2, CDH11, LTBP3, MATN3, EDN1, BMP2, TLE5, TEAD4, WFIKKN1, GDF3, HOXA11, ZBTB16, FOXC1, JAG2, HOXC4, COMP, COL9A2, COL19A1, CMKLR1, SH3PXD2B, ALPL, GLI2, EVC, ROR2, IHH, ADAMTS4, PKDCC, NCAN, SMAD3, AHSG, ETS2, SPP2, DLL3, EIF2AK3, HOXA10, ARSL, HOXA4 |
| skeletal system morphogenesis | biological process | MMP2, FGFR2, FGFR1, COL11A1, RYK, HOXD8, ZFAND5, RFLNB, PRKRA, PLEKHA1, NKX3-2, ARID5B, COL2A1, ACVR2B, TIPARP, PSEN1, ANKRD11, CSRNP1, TGFBR1, WDR48, HOXB4, HYAL2, SIX1, P2RX7, RAB33B, ALX4, FGR, RUNX2, PDGFRB, NLE1, PDGFRA, HOXB8, HHIP, HOXB2, HOXC8, TCF15, SH3PXD2B, FMN1, RFLNA, WWOX |
| skin development | biological process | GNAS, ERCC2, CTNNB1, ITGA6, SHH, PKD1, DDR1, COL5A2, WNT10A, COL3A1, RYR1, LTB, DHCR24, ASCL4, SLC2A10, BCL11B, GJB3, SLITRK5, PTCH2, IRF6, OVOL1, PDGFA, DSP, FRAS1, ATP8A2, SUFU, SFN, ARRDC3, ATP7A, WDR48, ADAMTS2, ASPRV1, ABCB6, COL5A1, EDA, JUP, COL5A3, SOX21, NGFR, KRT9, COMP, TCF15, SLC27A4, ITGA3, DACT2 |
| skin epidermis development | biological process | AP3B1, DLL1 |
| skin morphogenesis | biological process | TP63, GBA, ERRFI1, ITGA2, PSEN1, COL1A2, ITGB4, SRF |
| sleep | biological process | IL18, OXTR, OXT, PTGDR, MRGPRX2, CACNA1I, FOS, HCRT, DLAT, GRIN2A, SLC29A1 |
| slit diaphragm assembly | biological process | PTPRO |
| slow axonal transport | biological process | HSPA8 |
| slow endocytic recycling | biological process | MICALL1 |
| slow-twitch skeletal muscle fiber contraction | biological process | MB, TNNT1 |
| SMAD protein complex assembly | biological process | TGFB1, SMAD4, SMAD2, SMAD3 |
| SMAD protein import into nucleus | biological process | TGFB1, TGFB3 |
| SMAD protein signal transduction | biological process | TGFB1, INHBA, TGFB3, NODAL, VIM, BMP7, GDF15, GDF9, BMP15, BMP4, INHA, NUP93, SMAD4, PIAS2, SUB1, ZMIZ1, CITED1, GDF11, SKI, BMP5, TGFB2, HIPK2, LEFTY1, RBM14, SLC33A1, SMAD2, LNPEP, BTBD11, FOS, BMP6, HNF4A, MSTN, BMP2, GDF3, INHBC, INHBE, GDF7, ROR2, GDF2, LEFTY2, SMAD9, GDF1, ZMIZ2, SMAD3, MAGI2, SMAD5, GDF5 |
| small GTPase mediated signal transduction | biological process | HMOX1, YWHAQ, CDC42, RAP1A, SOS1, RABL2A, USO1, DIRAS3, RIN2, RAB18, RALGPS1, RGL4, RAB38, NUCB2, ARHGAP32, SIAH2, GDI2, RHOU, RALGPS2, RASGRP3, RAPGEF2, RND2, PLD1, RALBP1, RAPGEFL1, VAV3, RAB4A, CHML, RUFY1, BCR, ABR, RAPGEF6, ARHGAP33, RASGRP1, ARL3, CCDC88A, RHOD, RND3, RHOG, RASGRP4, RASGRP2, RIT2, RAPGEF1, DOCK11, DOCK9, RHOF, RGL1, PLCE1, SOS2, DOCK5, HACD3, RHOQ, TIAM1, RHEB, ARHGAP31, RGL3, DOCK7, RAC1, ARHGAP1, ARHGAP18, DOCK8, KRIT1, RAC2, VAV2, DOCK3, CCDC88C, DOCK1, CHP1, RHOBTB1, RABIF, DOCK6, RGL2, RASGRF2, KNDC1, PLD2, RGS19, RAC3, RASGEF1A, BCAR3, RAPGEF3, HRAS, ARHGAP30, RASL10A, RHOJ, SH2D3C, RHOV, RHOC, VAV1, RALGDS, RHOH, SH2D3A, NUCB1, ARHGEF18, RASGEF1C, RHOBTB2, RRAD, RASGRF1, ITSN1, PLCD4, TIAM2, DOCK2, RAP1B, RUNDC3A, DOCK4, DOCK10, GDI1, RHEBL1, RAPGEF4 |
| small molecule metabolic process | biological process | GLRX5, ISCA2, FXN, ISCA1, FDX1, ISCU, LYRM4, NFS1, FDX2 |
| small-subunit processome assembly | biological process | XRCC5, PRKDC |
| smooth endoplasmic reticulum calcium ion homeostasis | biological process | APP, PSEN1 |
| smooth muscle adaptation | biological process | IL1B |
| smooth muscle cell chemotaxis | biological process | PARVA, PDGFRB |
| smooth muscle cell differentiation | biological process | CTNNB1, BMP4, ACVR1, WNT4, MRTFA, TMEM204, MEF2C, MRTFB, MYOCD, HEY2, NFATC4, FOXF1, FGF10 |
| smooth muscle cell migration | biological process | PLAU, PLAT, DDR1, ARPC5, ITGB3, CCN3 |
| smooth muscle cell proliferation | biological process | EDNRA, NAA35, CCN3, AGT |
| smooth muscle cell-matrix adhesion | biological process | DDR1, VTN |
| smooth muscle contraction | biological process | EDNRA, BDKRB2, ROCK2, MYH11, HTR7, ROCK1, MLN, CHRM3, ADRA1A, FKBP1B, PDE4D, SMTN, TPCN2, NMUR1, CHRNB2, MYLK, CHRNB4, HTR2B |
| smooth muscle contraction involved in micturition | biological process | KCNMA1, TRPV1 |
| smooth muscle hyperplasia | biological process | NOS3, HMOX1 |
| smooth muscle hypertrophy | biological process | CYBA |
| smooth muscle tissue development | biological process | BMP4, TP63, ZFAND5, TIPARP, SMO, DLG1, FOXP2, PDGFRB, ENG, PTCH1, IHH, STRA6, NF1, ITGA8 |
| smoothened signaling pathway | biological process | BMP4, SHH, GLI3, RO60, SEPTIN2, DZIP1, GPC2, WDR19, IFT57, DISP2, NKX2-2, TMEM17, TCTN2, IFT52, TTC26, TCTN3, HES1, NSDHL, B9D1, HIPK1, ARL3, IQUB, PKD2L1, PDX1, ARL13B, DYRK2, IFT46, PTCH2, CDON, HHAT, TTBK2, TTC21B, DZIP1L, SMO, HIPK2, TBC1D32, KIAA0586, IFT80, SUFU, PTCHD1, DHH, MAP3K10, GLI1, TGFBR2, FKBP8, STIL, WNT10B, FOXF1, GLI2, EVC, ROR2, PTCH1, IHH, DISP3, EVC2, CC2D2A, IFT172 |
| smoothened signaling pathway involved in dorsal/ventral neural tube patterning | biological process | GLI3, WDR19, TULP3, TBC1D32, IFT122, GLI2, PTCH1 |
| smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation | biological process | SHH, SMO, GLI1, GLI2 |
| smoothened signaling pathway involved in spinal cord motor neuron cell fate specification | biological process | GLI3, SUFU, GLI2 |
| smoothened signaling pathway involved in ventral spinal cord interneuron specification | biological process | GLI3, SUFU, GLI2 |
| smoothened signaling pathway involved in ventral spinal cord patterning | biological process | SMO |
| SNARE complex assembly | biological process | SNCA, VAMP8, VAMP1, VAMP4, VAMP3, VAMP7, UVRAG, STX4 |
| SNARE complex disassembly | biological process | NSF, NAPA, NAPB |
| snoRNA catabolic process | biological process | NUDT16 |
| snoRNA guided rRNA pseudouridine synthesis | biological process | NOP10, NAF1, GAR1 |
| snoRNA localization | biological process | NOP58, ZNHIT3, PRPF31, FBL, ZNHIT6 |
| snoRNA metabolic process | biological process | FBL |
| snoRNA polyadenylation | biological process | TENT4B, TENT4A |
| snoRNA splicing | biological process | RNF113B |
| snRNA (adenine-N6)-methylation | biological process | METTL16, METTL4 |
| snRNA 3'-end processing | biological process | INTS7, TOE1, INTS2, CT45A8, CT45A9, CT45A2, INTS8, INTS14, INTS6, INTS12, SAGE1, INTS5 |
| snRNA catabolic process | biological process | MTREX, ZCCHC8, RBM7 |
| snRNA export from nucleus | biological process | NCBP2 |
| snRNA import into nucleus | biological process | RAN, SNUPN |
| snRNA metabolic process | biological process | MEPCE |
| snRNA modification | biological process | MEPCE |
| snRNA processing | biological process | TUT1, INTS7, INTS10, INTS9, INTS2, INTS3, INTS8, INTS6, INTS12, INTS11, INTS5, INTS4, INTS1 |
| snRNA pseudouridine synthesis | biological process | DKC1, NOP10, NHP2 |
| snRNA transcription | biological process | SNAPC4, USPL1, SNAPC3, SNAPC2 |
| snRNA transcription by RNA polymerase III | biological process | SNAPC1, ZC3H8, ICE2, ELL, SNAPC5, SNAPC4, ICE1, SNAPC3 |
| snRNA transcription from RNA polymerase II promoter | biological process | SP1, CDK9, NCBP2, GTF2A2, POLR2F, TAF5, SNAPC1, ZC3H8, CDK7, RPRD2, POLR2G, INTS7, ELL2, CCNT1, GTF2F1, ICE2, INTS10, ELL, INTS9, GTF2B, NCBP1, ELL3, POLR2B, POLR2D, TAF13, TAF11, SNAPC5, INTS2, POLR2J, POLR2L, SRRT, CCNK, POLR2E, GTF2A1, SNAPC4, INTS3, ICE1, NABP1, ZNF143, POLR2K, POU2F2, POLR2I, TAF6, INTS8, SNAPC3, INTS14, GTF2F2, INTS6, INTS12, RPRD1A, POLR2C, RPRD1B, POU2F1, INTS11, INTS5, NABP2, POLR2H, GTF2E2, INTS4, POLR2A, INTS1, SNAPC2, GTF2E1, TAF9 |
| social behavior | biological process | IL1B, MTOR, PTEN, OXTR, OXT, PCM1, KALRN, GRIN1, NLGN4X, DVL1, EIF4EBP2, NRXN1, MKKS, GRP, BBS4, NRXN2, GAD1, SHANK2, NRXN3, UCN, CNTNAP2, ATXN1, NLGN4Y, ATXN1L, MECP2, SLC6A4, CX3CR1, PTCHD1, DLG4, GNG8, DRD3, EN1, GNB1L, AVP, TH, SEPTIN5, CHRNB2, CHD8, BRINP1, MAPK8IP2, NPAS4, CIC, GRID1, SHANK1, DRD4 |
| sodium ion export across plasma membrane | biological process | SLC9A1, SLC4A4, ATP1A4, ATP1A3, ATP1A2, SLC8A1, ATP1B1, FXYD2, ATP1A1, ATP1B2, ATP4A, ATP1B3, ATP4B |
| sodium ion homeostasis | biological process | CYP11B2, SLC12A2, CYP4A11, SCNN1G, SCNN1A, CYP4F12, CYP4F2, SCNN1B, SLC12A3, UPK3A, MC3R |
| sodium ion import across plasma membrane | biological process | SLC12A2, SLC9C1, SLC9A2, SLC9A1, SLC9A7, SLC9A9, SLC9C2, SLC8A1, HCN2, SLC5A1, SLC9A6, SLC5A2, TRPM4, HCN4, SLC34A1 |
| sodium ion transmembrane transport | biological process | CATSPER4, ASIC4, ASIC1, SCN11A, SLC12A2, ASIC2, SLC17A3, SLC24A5, SLC24A4, SLC20A1, ANO6, SLC41A1, SLC4A7, SLC4A4, PKD2, SLC17A1, PKD2L1, SCN1B, ATP1A4, CNNM4, SCNN1G, SLC8A3, ATP1A2, SLC9B2, SCN2A, SLC8A1, CACNA1G, SCN1A, SCNN1A, CACNA1I, SLC4A11, SLC24A3, HCN2, ATP1B1, SLC23A1, KCNK1, HCN1, SCNN1D, CACNA1H, SLC4A8, SLC34A3, SLC3A2, SLC5A10, SCN4A, ATP1B3, SLC20A2, SCN4B, HCN4, SHROOM2, TRPM5, TRPM2, ABCB11, SCNN1B, SLC12A3, SCN5A, SLC8B1, ASIC3, SLC8A2, NALCN, SLC28A3, TPCN1, SCN10A, SLC17A2, SCN2B, SLC4A10, SLC4A9, SCN3B, SLC17A7, SCN8A, SLC24A1 |
| sodium ion transport | biological process | SLC13A3, SLC22A5, CATSPER4, CATSPER3, SLC6A8, SLC5A8, ASIC4, ASIC1, SCN11A, SLC12A2, ASIC2, SLC38A7, SLC17A3, SLC38A6, SLC24A5, SLC24A4, SLC20A1, COMMD3, SLC4A7, FXYD1, MFSD4B, SLC38A1, SLC38A11, SLC13A2, SLC5A12, SLC9C1, SLC9A2, SLC9A1, SLC9A7, SLC4A4, SLC17A1, SLC10A6, SLC6A15, SCN1B, ATP1A4, SLC9A9, SLC38A2, SLC38A10, SCNN1G, SLC8A3, FXYD3, ATP1A3, SLC13A1, SLC17A6, ATP1A2, SLC9B2, SLC38A4, SCN2A, SLC9C2, NEDD4L, SGK1, SLC8A1, NDUFA9, SCN1A, SCNN1A, SLC4A11, SLC24A3, HCN2, ATP1B1, SLC23A1, HCN1, SLC5A1, SCNN1D, FXYD2, SLC9A6, SLC5A7, SLC22A4, SLC5A6, ATP1A1, ATP1B2, SLC5A2, SLC4A8, SLC34A3, SLC5A10, SCN4A, ATP1B3, SLC20A2, SCN4B, HCN4, SLC38A8, SLC13A5, TRPM2, SCNN1B, SLC12A3, SLC34A1, SCN5A, SLC8B1, SLC5A5, SLC38A3, SLC23A2, ASIC3, SLC8A2, SLC10A7, SLC5A9, NALCN, SCN10A, SLC17A2, SCN2B, SLC4A10, SCN3B, SLC17A7, SCN8A, ATP4B, SLC10A2 |
| sodium-dependent organic anion transport | biological process | SLC10A6 |
| sodium-dependent organic cation transport | biological process | SLC22A5 |
| sodium-dependent phosphate transport | biological process | SLC34A3, SLC34A1 |
| sodium-independent organic anion transport | biological process | ALB, SLCO6A1, SLCO1B3, SLC22A9, MFSD10, SLCO5A1, SLCO1A2, SLCO4C1, SLCO2B1, SLCO2A1, SLCO4A1, SLCO1C1, SLCO3A1 |
| soft palate development | biological process | COL11A2, TSHZ1, SOX11, FOXE1 |
| somatic cell DNA recombination | biological process | SWAP70 |
| somatic diversification of immune receptors via somatic mutation | biological process | ADAR |
| somatic diversification of immunoglobulins | biological process | CTNNBL1, POLB |
| somatic hypermutation of immunoglobulin genes | biological process | POLQ, MLH1, PMS2, MSH2, EXO1, MCM3AP, MSH6, SAMHD1, POLB, POLL, UNG |
| somatic motor neuron differentiation | biological process | TCTN1, PHOX2A |
| somatic muscle development | biological process | PPP2R3A, NEB, NKD1 |
| somatic recombination of immunoglobulin gene segments | biological process | MLH1, MSH2, MSH6, UNG |
| somatic recombination of immunoglobulin genes involved in immune response | biological process | MLH1, MSH2 |
| somatic stem cell division | biological process | CDKN2A, KIT, NOTCH1, WNT3A, FZD7, TGFB2, VANGL2, ZFP36L2, HOXB4, WNT7A |
| somatic stem cell population maintenance | biological process | SOX9, LIG4, STAT3, KIT, RAF1, SOX2, KLF4, POLR2F, SPI1, TDGF1, POLR2G, SMAD4, BCL9, HES1, ASCL2, POLR2B, POLR2D, REST, FOXP1, SKI, SALL4, POLR2J, POLR2L, POLR2E, PBX1, VANGL2, ZFP36L2, DPPA4, POLR2K, RBPJ, KLF10, BCL9L, POLR2I, GATA2, YAP1, SOX4, SMAD2, EPHA1, LRP5, POLR2C, CDX2, VPS72, SALL1, LDB2, ZIC3, FGF2, POLR2H, PRDM16, POLR2A, ZSCAN10, WNT7A, ZHX2, FOXD3, FGF10, LIN28A |
| somatostatin secretion | biological process | NPFF, CARTPT |
| somatostatin signaling pathway | biological process | SSTR4, SSTR3, SSTR5 |
| somatotropin secreting cell development | biological process | GHRHR |
| somatotropin secreting cell differentiation | biological process | PROP1, WNT4, PITX2 |
| somite development | biological process | MTHFD1, SHH, PPP2R3A, RBBP6, FRZB, SMO, SOX11, NUP133, WNT11, LOXL3, MEOX2, PTCH1, IHH |
| somite rostral/caudal axis specification | biological process | SMAD4, TMED2, LHX1, EPB41L5, NRARP, GDF3, MESP1, TBX6 |
| somite specification | biological process | COBL, DLL1, MEOX2 |
| somitogenesis | biological process | ZEB2, ATM, XRCC2, MIB1, TCAP, NKX3-1, BMPR1A, WNT3A, MSGN1, TMED2, PSEN1, HES7, EPB41L5, EP300, PRKDC, RBPJ, ABI1, FOXC2, PAX1, PALB2, LEF1, POGLUT1, MED12, SFRP2, FOXB1, SEMA3C, NLE1, AXIN2, PCDH8, FOXF1, CRB2, KAT2A, DLL1, FOXC1, POFUT1, TCF15, PLXNA2, ROR2, LFNG, TBX19, SMAD3, DLL3, TP53 |
| sorbitol biosynthetic process | biological process | AKR1B1 |
| sorbitol catabolic process | biological process | SORD |
| sorbitol metabolic process | biological process | SORD |
| specification of animal organ identity | biological process | TBR1 |
| specification of animal organ position | biological process | BMP4, HOXA3, TBX3 |
| specification of axis polarity | biological process | BCOR, AHI1 |
| specification of loop of Henle identity | biological process | IRX1, IRX3 |
| specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway | biological process | BMP4 |
| Spemann organizer formation | biological process | CUSTOS, FZD5 |
| Spemann organizer formation at the anterior end of the primitive streak | biological process | WNT3 |
| sperm axoneme assembly | biological process | UBE2B, SPAG16, CFAP65, ARMC2, BBS2, NEURL1, TPGS1, TTLL1, PLA2G3 |
| sperm capacitation | biological process | CFTR, CABYR, BSPH1, CATSPER4, CATSPER3, SLC26A8, 38231, SLC26A3, ABHD2, PCSK4, ROPN1B, CATSPERD, SLC26A6 |
| sperm chromatin condensation | biological process | TSSK6, H1FNT, SYCP1, SRPK1 |
| sperm displacement | biological process | EDDM3A |
| sperm ejaculation | biological process | OXTR, OXT, SLC6A4, ACVR2A |
| sperm entry | biological process | UBE3A |
| sperm mitochondrion organization | biological process | 38231, MFSD14A |
| sperm-egg recognition | biological process | CATSPER1, CATSPER2, IZUMO1, SPAM1, SPACA3, CATSPER4, CATSPER3, CATSPERB, HVCN1, CATSPERG, CATSPERD |
| spermatid development | biological process | PRM1, PRM2, CIB1, RNF17, PANK2, TNP1, HSPA2, ODF2, PIWIL1, SPO11, REC8, KIT, DPY19L2, INSL6, GAPDHS, MEI1, DDX25, RNF8, GALNTL5, PACRG, PYGO2, ZMYND15, 38231, KLHL10, CAPZA3, DMC1, CEP57, TTC21A, SMARCA2, NME5, NSUN2, TTC26, CCDC42, MFSD14A, JAM3, MKKS, TARBP2, TRIP13, ING2, FANCG, CCDC63, BBS4, CCNB1IP1, RIMBP3B, ACRBP, FSCN3, OSBP2, MEIOC, NUP210L, QKI, PYGO1, DHH, OCA2, BRIP1, JAM2, FAM9A, FAM9C, FAM9B, SIX5, H3-3A, SPANXB1, FNDC3A |
| spermatid differentiation | biological process | BAX, NPHP1, MAST2, NME5, DDX6, RHBDD1 |
| spermatid nucleus differentiation | biological process | TNP1, PYGO2, AGFG1, TBPL1, MFSD14A, PYGO1 |
| spermatid nucleus elongation | biological process | TNP1, H1FNT, Dmrtc2 |
| spermatogenesis | biological process | USP9Y, SOD1, PRM1, ACE, FSHR, BRD2, FAS, SOX9, INSL3, BRCA2, BAX, DAZ2, TSSK4, DAZ4, CATSPER1, BCL2L2, CATSPER2, TSSK6, DAZ1, DNMT3L, AURKC, APOB, PRM2, ERCC1, CCNB1, CDC25C, AXL, NR0B1, UBE2B, HSF1, E2F1, HSF2, BRDT, UBR2, CIB1, RNF17, DMRT1, TNP1, BAG6, HSPA2, RAD23B, TNP2, PRDX4, ODF2, PIWIL2, DAZL, BAD, PIWIL1, SPO11, BPY2, MSH4, REC8, SERPINA5, KIT, IGF2R, MLH1, NANOS2, TSPY1, SOHLH1, TXNDC8, DPY19L2, TEX15, SPACA1, DDX4, DAZ3, INSL6, NPHP1, CLDN11, PLAU, H2AFX, MAK, TAF7L, H1FNT, STRA8, TXNDC2, NME8, SPATA9, SPATA16, PROK2, CYP26B1, DNAH9, DDX25, RNF114, CLOCK, PAFAH1B2, CREM, SPAG11B, CATSPER4, PIWIL4, GALNTL5, HORMAD1, CATSPER3, BOLL, TDRD9, GTSF1, TCP11, TAF4B, GMCL1, MAEL, ADCY10, SLC26A8, MOV10L1, ZMYND15, TP63, SPANXA1, SOHLH2, OAZ3, CDY2A, CDY1, WIPF3, FKBP6, SBF1, MAS1, AGFG1, LIMK2, NANOS3, TBPL1, CCNA1, GAMT, SYCP1, SPA17, UTP14C, KLHL10, PIWIL3, NLRP14, SPATA25, PATZ1, YBX2, CFAP69, SKIL, DMC1, SEPTIN2, DZIP1, SIAH1, KASH5, TTC21A, MNS1, ARMC2, TDRD7, PSMA8, PMFBP1, M1AP, RPL10L, PIAS1, YBX3, |
| spermatogenesis, exchange of chromosomal proteins | biological process | SYCP3, CHD5 |
| spermatogonial cell division | biological process | BRIP1 |
| spermidine acetylation | biological process | SAT1, SATL1, SAT2 |
| spermidine biosynthetic process | biological process | AMD1, AGMAT, SRM |
| spermidine catabolic process | biological process | PAOX |
| spermine acetylation | biological process | SAT2 |
| spermine biosynthetic process | biological process | AMD1, SMS |
| spermine catabolic process | biological process | PAOX, SMOX |
| spermine metabolic process | biological process | PAOX, SMS |
| spermine transmembrane transport | biological process | ATP13A2 |
| spermine transport | biological process | TAF7 |
| sphinganine biosynthetic process | biological process | SPTLC1, SPTLC2 |
| sphinganine metabolic process | biological process | DEGS2 |
| sphinganine-1-phosphate biosynthetic process | biological process | SPHK2 |
| sphinganine-1-phosphate metabolic process | biological process | SGPP1 |
| sphingoid biosynthetic process | biological process | SPTLC3 |
| sphingolipid biosynthetic process | biological process | SPHK2, HACD1, SGMS2, PLPP2, VAPB, PRKD1, ELOVL6, ALDH3A2, CERS5, ELOVL4, PLPP1, SGPP2, PPM1L, DEGS2, HACD2, ELOVL2, ELOVL5, VAPA, DEGS1, PRKD3, SPTLC3, HACD3, ACER3, CERT1, CSNK1G2, FA2H, SPTLC1, SPTSSA, SAMD8, CERS4, SPTLC2, ALDH3B1, PRKD2, PLPP3, CERS1, CERS6, CERS3, ELOVL1, ACER1, ELOVL3, ACER2, SGPP1 |
| sphingolipid catabolic process | biological process | PPT1, ENPP2, PDXDC1 |
| sphingolipid mediated signaling pathway | biological process | SMPD3 |
| sphingolipid metabolic process | biological process | GBA, ARV1, SPHK2, SGMS2, B4GALNT1, PDXDC1, TEX2, CERS5, PSAP, GALC, SFTPB, SERINC3, SERINC1, SMPD3, SPTLC3, ACER3, TECR, CERK, B4GALT6, ZPBP2, FA2H, GBA2, SPTLC1, SERINC5, SPTSSA, SAMD8, B4GALT5, ST8SIA1, ALOXE3, CERS4, SMPD2, SPTLC2, TH, CERS1, CERS6, CERS3, SPNS2, ACER1, ALOX12B, SERINC2, UGCG, AGK, ACER2, SGPP1, ASAH2, GM2A, UGT8 |
| sphingomyelin biosynthetic process | biological process | SGMS2, PEMT, SPTLC1, SAMD8, SPTLC2 |
| sphingomyelin catabolic process | biological process | SMPD1, SMPDL3A, SMPD3, SMPDL3B, SMPD2, SMPD4, ENPP7 |
| sphingomyelin metabolic process | biological process | SMPD1, SMPD3, SMPD2, ENPP7 |
| sphingosine biosynthetic process | biological process | GBA, SPHK2, SPTLC3, ACER3, SPTLC1, SPTLC2, ACER1, ABCA2, ACER2, ASAH2 |
| sphingosine metabolic process | biological process | SPHK2, PLPP2, PLPP1, SGPP2, PLPP3, SGPP1, ASAH2 |
| sphingosine-1-phosphate signaling pathway | biological process | EZR, SPHK2, S1PR1, S1PR2, S1PR5, S1PR3, S1PR4, SPNS2 |
| spinal cord anterior/posterior patterning | biological process | GDF11 |
| spinal cord association neuron differentiation | biological process | PAX7, MDGA1, LHX3, WNT3A, LHX1, ASCL1, LHX5, GDF7, GSX1 |
| spinal cord development | biological process | ERCC2, AKT1, SRD5A1, MTOR, PKD1, EED, ACTL6A, PTN, BAG3, SOX12, ROBO2, PKD2, LHX1, SOX11, ZPR1, NPFF, PHGDH, SOX4, MED12, FOXB1, MPST, LOXL3, PLXDC1, PTPRS, DLL1, ACTL6B, VIT, NF1, NEFL |
| spinal cord dorsal/ventral patterning | biological process | SHH, GLI3, INTU, SUFU, GLI2 |
| spinal cord motor neuron cell fate specification | biological process | OLIG3, ISL1, LHX3, HOXC10, HOXD10, MNX1 |
| spinal cord motor neuron differentiation | biological process | SHH, DYNC2H1, GLI3, OLIG3, ISL1, NKX2-2, ZC4H2, GDPD5, GBX1, SOX4, SCYL1, SCYL3, LBX1, NFE2L1, GIGYF2, GLI2, PTCH1, MDGA2, IFT172 |
| spinal cord motor neuron migration | biological process | OLIG3 |
| spinal cord oligodendrocyte cell differentiation | biological process | NKX2-2, ASCL1, SOX6 |
| spinal cord oligodendrocyte cell fate specification | biological process | NKX2-2, ASCL1 |
| spinal cord patterning | biological process | RELN |
| spinal cord ventral commissure morphogenesis | biological process | ADARB1, DCC, GLI2 |
| spindle assembly | biological process | STARD9, KASH5, HAUS2, TUBGCP4, GOLGA8A, HAUS4, MAPRE3, TNKS, RPS3, HAUS5, CSNK1D, GOLGA6B, TUBB, TUBGCP3, GOLGA8N, MAP9, GOLGA8M, CEP63, HAUS6, CENPW, HDAC3, NCOR1, RCC1, MAPRE1, TUBGCP5, TUBGCP2, TUBGCP6, NEK6, INO80, GOLGA2, NEK2, KIF11, NEK7, GOLGA6A |
| spindle assembly involved in female meiosis | biological process | TUBB8 |
| spindle assembly involved in meiosis | biological process | WASHC5, ASPM, GOLGA2 |
| spindle checkpoint | biological process | BIRC5 |
| spindle localization | biological process | WASL, KASH5, ACTR3, ASPM, ACTR2 |
| spindle midzone assembly | biological process | AURKC, LZTS2 |
| spindle organization | biological process | ASPM, KIZ, NTMT1, TTK, UVRAG, KNSTRN, CKAP5, AUNIP, RGS14, CHD3, AURKB, CEP72, KIF11 |
| spine apparatus assembly | biological process | SYNPO |
| spleen development | biological process | BCL2, FAS, RBM15, FLVCR1, BCL2L11, BCL3, EPB42, NKX3-2, PCID2, NKX2-3, FADD, JARID2, CDKN2B, RC3H2, NFKB2, PBX1, CDH17, PRKDC, RC3H1, ABL1, CITED2, HOXB4, SLC40A1, RIPK3, PKN1, ONECUT1, POLB, NKX2-5, FGF10, PITX2 |
| spleen trabecula formation | biological process | SLC40A1 |
| spliceosomal complex assembly | biological process | DDX1, SF3B1, TXNL4A, PRPF19, DDX39B, PRPF6, NCBP1, SRPK1, SRPK2, SNRPE, GEMIN6, SNRPD1, SNRPD2, SNRPG, USP39, SMN1, SCAF11, ZRSR2, SF1, SRPK3, SF3A2, CRNKL1 |
| spliceosomal complex disassembly | biological process | TFIP11 |
| spliceosomal snRNP assembly | biological process | CLNS1A, COIL, WDR77, STRAP, SNRPC, SART3, SNRPE, GEMIN6, SNRPB, GEMIN5, DDX20, GEMIN4, SNRPD1, SNRPD2, SNRPG, TGS1, GEMIN8, SMN1, SNUPN, SNRPF, GEMIN7, SART1, PRMT7, LSM4 |
| spliceosomal tri-snRNP complex assembly | biological process | SRSF12, PRPF19, PRPF6, SART3, PRPF31, CD2BP2, DDX20, PRPF3, PRPF8, USP4, LSM2 |
| spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) | biological process | SNRNP200 |
| spongiotrophoblast differentiation | biological process | LIF, ASCL2, GJB5, SOCS3 |
| spongiotrophoblast layer development | biological process | ADM, SENP2, ASCL2, CITED1, BIRC6, ZFP36L1, FBXW8, ZFAT |
| spontaneous exocytosis of neurotransmitter | biological process | SYT12 |
| spontaneous neurotransmitter secretion | biological process | RIMS2, SYT1, STX1B, DOC2A, RPH3A, DOC2B |
| spontaneous synaptic transmission | biological process | CBLN2, NSG1 |
| sprouting angiogenesis | biological process | PGF, CDC42, SEMA3E, CCBE1, ADGRA2, LOXL2, FLT4, RAMP2, NOTCH1, THBS1, TEK, OTULIN, ANGPT1, RNF213, YJEFN3, VEGFC, NRARP, PARVA, LEF1, E2F7, RSPO3, E2F8, CDH13, ESM1, VEGFB, ENG, NRP1, PTK2B |
| squamous basal epithelial stem cell differentiation involved in prostate gland acinus development | biological process | FGFR2, TP63 |
| SREBP signaling pathway | biological process | ERLIN1, SCAP, SREBF2, EIF2A, ARHGEF10L, INSIG1, ERLIN2, SREBF1, INSIG2 |
| SREBP-SCAP complex retention in endoplasmic reticulum | biological process | INSIG1, INSIG2 |
| SRP-dependent cotranslational protein targeting to membrane | biological process | RPL4, RPL3, RPL5, RPS10, SRP9, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, RPL24, RPL6, RPLP0, RPL29, RPL15, RPS8, RPL7A, RPL32, RPS21, RPL7, RPL13, RPS18, RPS13, RPL11, RPL19, SEC63, SRP19, RPL35A, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, SRPRA, RPS2, RPL9, RPS19, RPS5, RPS25, RPL30, RPS27A, RPL38, RPS3, RPL13A, RPL35, RPLP1, RPS12, SRP14, RPS27, RPL39, RPS4Y1, RPL8, RPL27A, RPL18A, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, SSR3, RPL14, RPL37, RPS15A, RPS24, RPS28, RPL36, RPL10, SRP54, SRP72, RPLP2, RPS17, RPL23A, RPL18, UBA52, RPSA, RPS11, RPL36A, RPL17, RPL23, RPL26, SEC61A1 |
| SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition | biological process | SRP19, SRP54 |
| SRP-dependent cotranslational protein targeting to membrane, translocation | biological process | TRAM1, ZFAND2B, TRAM2, SEC61B, SRP54, SEC61A2, SEC61A1, TRAM1L1 |
| stabilization of membrane potential | biological process | KCNK9, KCNK17, KCNK4, KCNK2, KCNN4, KCNK10, KCNK18, KCNK1, KCNK15, KCNK3, CHCHD10, KCNK7, KCNK13, KCNK6 |
| starch catabolic process | biological process | MGAM |
| startle response | biological process | NRG1, GRIN1, PRKN, UCN, MECP2, SLITRK6, FABP7, GLRA1, GRIN2A, CSMD1, NPAS1, CHD8, DRD2, KCNA1, GRIN2D, PENK |
| STAT protein import into nucleus | biological process | EGF, F2R |
| stem cell development | biological process | SHH, PTPRC, WNT7A |
| stem cell differentiation | biological process | LIF, SOX10, A2M, KIT, PUM1, EPCAM, GPM6A, PHF5A, ELL3, SETD6, ZNF281, MSX1, JARID2, HMGA2, PDX1, SHC4, HOXA7, MTF2, RUNX2, MSX2, FOXO4, NELFB, SOX21, ESR1, LIN28A |
| stem cell division | biological process | GNL3, TIAL1, THOC2, WWTR1, ESRRB |
| stem cell fate specification | biological process | SOX18 |
| stem cell population maintenance | biological process | LIF, NODAL, FGFR1, CTNNB1, STAT3, KIT, MED7, LSM1, KLF4, EOMES, GNL3, SMC3, PAF1, BMPR1A, PELO, EIF4ENIF1, SETD6, RTF1, KDM4C, MED21, MED10, CTR9, TRIM8, MED14, NKAP, FZD7, CDC73, SALL4, EIF4E, DDX6, NIPBL, SMC1A, TET1, MED30, MED28, ARID1A, RIF1, TBX3, MTF2, MED12, MED15, TUT4, LEO1, PADI4, DIS3L2, PRDM16, ESRRB, MED27, LIN28A |
| stem cell proliferation | biological process | ABCB1, CD34, WNT7B, RNF43, TRIM71, FGF2, WNT3, ZNRF3, NES |
| stereocilium maintenance | biological process | TPRN |
| steroid biosynthetic process | biological process | CYP19A1, HSD17B1, SRD5A2, CYP17A1, HSD17B3, NR0B1, CYP11A1, HSD3B1, CYP11B1, PRLR, SRD5A1, HSD3B2, HSD17B2, CYP21A2, CYP11B2, IDI1, LBR, ACBD3, SCP2, FDFT1, LSS, STAR, HSD17B7, PMVK, NSDHL, SC5D, DHCR24, HSD17B8, HMGCR, EBP, FDX1, MSMO1, CH25H, HMGCS2, HMGCS1, HSD3B7, PBX1, CYB5R2, CYB5R3, PRKAA2, HINT2, ERG28, HSD17B11, TRERF1, CYP51A1, TM7SF2, HSD17B12, DHRS11, RDH8, DHCR7, MVD, MVK |
| steroid catabolic process | biological process | SRD5A2, CYP1A2, HSD17B14, HSD11B1, STS |
| steroid hormone mediated signaling pathway | biological process | NR5A2, ESR1, PGR, AR, VDR, NR5A1, ESR2, NR1I2, NR0B1, NR3C1, BMP7, BMP4, THRB, NR2F2, PPARG, NR1H3, NR1D2, PGRMC2, ESRRG, RARB, HNF4G, PAQR8, PPARD, ABHD2, RORA, NR2E3, NR2F6, NR4A2, NR1H4, NR2C1, LEF1, ESRRA, NR1D1, HNF4A, NR2F1, RXRG, NR4A3, RARG, NR4A1, PPARA, THRA, RORC, ESRRB, NR3C2, PAQR7, RARA, NR2C2, NR1H2, GPER1 |
| steroid hormone receptor complex assembly | biological process | FKBP4 |
| steroid metabolic process | biological process | APOE, SRD5A2, NR1I2, APOB, CYP17A1, CYP1A2, CYP2B6, CYP11A1, CYP11B1, SRD5A1, AKR1C3, SULT1E1, SULT1A1, CYP21A2, CYP11B2, LIPE, CYP1B1, NPC2, SULT2A1, IDI1, LBR, ARV1, ERLIN1, UGT2B7, SCAP, FDFT1, SREBF2, UGT1A8, SULT4A1, SULT2B1, HDLBP, PMVK, NSDHL, DHRS9, SC5D, AKR1C2, MBTPS1, DHCR24, LDLR, UGT2B28, HMGCR, CYP2C8, VLDLR, EBP, HSD17B14, CRH, FDX1, APOF, MSMO1, CH25H, HSD11B1, HMGCS2, HMGCS1, SLC22A24, LIMA1, HSD17B6, CYP2A6, CYP2C19, APOA1, SOAT1, NPC1L1, UGT2B15, MBTPS2, GBA2, CYP3A5, CYB5R2, NPC1, INSIG1, CYB5R3, PRKAA2, ERG28, SULT1B1, ERLIN2, SREBF1, CYP51A1, UGT2B17, TM7SF2, SULT1A3, SULT1A4, NFE2L1, STARD3, DHRS11, RDH5, DHCR7, CYP2E1, MVD, CETP, SULT1A2, CYP46A1, CYP2D6, MVK, PCSK9, DISP3, CUBN, LCAT, AKR1D1, AKR1C1, APOL1, STS, CYP2C9, AKR1C4, APOBR, CYP3A43, INSIG2 |
| sterol biosynthetic process | biological process | IDI1, LBR, FDFT1, PMVK, NSDHL, PRKAG2, SC5D, DHCR24, HMGCR, EBP, MSMO1, CH25H, HMGCS2, HMGCS1, SQLE, CYB5R2, INSIG1, CYB5R3, PRKAA2, ERG28, CYP51A1, TM7SF2, FAXDC2, DHCR7, MVD, MVK, INSIG2 |
| sterol homeostasis | biological process | NR1H3, XBP1, NUS1, ABCD1 |
| sterol metabolic process | biological process | CYP19A1, CYP17A1, CYP11A1, CYP11B1, CYP21A2, CYP11B2, CYP1B1, ARV1, DHCR24, LIPA, EBP, FDX1, CYP26A1, CYP8B1, FDX2, CYP51A1, EBPL, CYP26C1, CYP46A1 |
| sterol transmembrane transport | biological process | SLC22A24 |
| sterol transport | biological process | GRAMD1C, SCP2, OSBPL1A, OSBPL11, OSBPL8, OSBP2, OSBPL9, OSBPL6, GRAMD1A, OSBPL10, OSBPL7, OSBP, OSBPL3, GRAMD1B |
| stilbene catabolic process | biological process | EPHX2 |
| stimulatory C-type lectin receptor signaling pathway | biological process | SRC, RAF1, CLEC7A, PSMA3, env, MALT1, PSMB1, PSMB5, PSMC2, CLEC6A, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, PSMD1, PSMD14, BCL10, PSMD7, MUC6, BTRC, MAP3K7, PSMB6, PSMD10, KRAS, PRKACB, PSMD8, PSMC5, PSMB4, SYK, PSME1, CUL1, CREBBP, PSMB8, PSMD4, TAB1, PSMC3, PSMA6, CLEC4C, RELA, CD209, MUC21, MUC15, IKBKG, EP300, TAB2, PSMD12, PSMB9, PSMC4, PSMD9, PSMA4, PSMD2, TRAF6, LYN, PRKACG, PRKCD, MUC7, PSMD5, TAB3, PSMF1, MUC4, PSMB3, IKBKB, CLEC10A, CARD9, PSMD3, RPS6KA5, PAK3, FCER1G, PSMC1, CLEC4A, HRAS, ICAM3, MUC17, CLEC4D, RELB, MUC12, PDPK1, MUC20, CARD11, PLCG2, PSMD13, PSMB10, MUCL1 |
| stomach neuroendocrine cell differentiation | biological process | ASCL1 |
| store-operated calcium entry | biological process | CRACR2A, STIM2, MS4A1, ORAI2, STIM1, ORAI3 |
| strand displacement | biological process | BRCA1, BRCA2, ATM, NBN, RTEL1 |
| strand invasion | biological process | XRCC2, DMC1, RAD51D |
| stress fiber assembly | biological process | ITGB1, SRC, SORBS1, PDCD10, FHDC1, ITGB5, TNFAIP1, KCTD13, PDLIM1, PHACTR1, SRF, FAM171A1, ELN, PTK2B, ZYX |
| stress granule assembly | biological process | PUM2, DYNC1H1, DDX3X, G3BP1, CSDE1, RPS23, LSM14A, C9orf72, ATXN2L, BICD1, GRB7, DDX6, PRRC2C, EIF2S1, G3BP2, OGFOD1, ATXN2, UBAP2L |
| stress granule disassembly | biological process | KIF5B, DYRK3, KLC1, ZFAND1 |
| stress-activated MAPK cascade | biological process | MAPK14, SKP1, MAPK11, BTRC, MAP3K7, CRYAB, RPS27A, MAP3K20, CUL1, MAP3K8, TAOK2, MAP2K7, IKBKG, MAP3K5, UBC, UBA52, IKBKB, TNIP2, CCM2, UBB, MAPK13, AGT |
| stress-activated protein kinase signaling cascade | biological process | AKR1B1, STK3, MAP3K4, MAP4K2, NEK1, STK4, MAP4K1, STK25, STRADB, MAP3K8, TAOK2, STK10, MAP4K3, MAP4K4, MAP2K4, MAP2K3, TAOK3, MAP2K7, PAK6, MAP3K3, MAP2K2, STRADA, TNIK, MAP3K19, SLK, CCDC88C, STK26, NEK4, TAOK1, MAP3K2, MAP2K6, MAP2K1, MAP3K14, PAK3, OXSR1, PAK4, MAP2K5, PAK5, MINK1, MAP3K1 |
| stress-induced mitochondrial fusion | biological process | STOML2 |
| stress-induced premature senescence | biological process | MAPK14, MAPKAPK5, CDKN1A |
| striatal medium spiny neuron differentiation | biological process | INHBA, BCL11B, ZSWIM6 |
| striated muscle atrophy | biological process | MYOG |
| striated muscle cell development | biological process | SDC1 |
| striated muscle cell differentiation | biological process | AKT1, RB1, SHH, MAPK14, BVES, KRAS, POPDC3, CDON, POPDC2, MYOD1, IGFBP5 |
| striated muscle contraction | biological process | MYH7, ARG2, GAA, MYOM2, ARHGEF11, CASQ2, DTNA, MYOM3, KLHL41, TTN, ALDOA, PGAM2, MYH6, MYOM1, MYLK2 |
| striated muscle myosin thick filament assembly | biological process | MYOM2, MYOM3, TTN, MYOM1 |
| striated muscle tissue development | biological process | SHH, PGM5, IFRD1, EYA1, EYA2 |
| striatum development | biological process | BBS2, RARB, MKKS, BBS4, SLITRK5, CNTNAP2, HPRT1, DRD1, SECISBP2, DRD2, LRRK2 |
| submandibular salivary gland formation | biological process | CDC42, FGF10 |
| subpallium development | biological process | FGF8, GLI3, DLX1, DLX2 |
| subpallium neuron fate commitment | biological process | ASCL1 |
| substance P catabolic process | biological process | ECE1 |
| substantia nigra development | biological process | NDRG2, HSPA5, G6PD, YWHAQ, ACTB, CDC42, FGF9, LDHA, DYNLL1, GLUD1, ATP5PB, CCDC14, ZNF430, ATP5PF, YWHAH, SEC16A, SUDS3, GNB4, SIRT2, PADI2, CALM1, CALM2, CALM3, MAPKAP1, RAD1, CNP, COX6B1, YWHAE, MBP, BASP1, SYPL2, CKB, MAG, ZNF148, SYNGR3, INA, TTBK1, S100A1 |
| substantia propria of cornea development | biological process | TGFB2 |
| substrate adhesion-dependent cell spreading | biological process | AXL, ITGAV, SRC, ITGA4, FN1, ANTXR1, LAMC1, FERMT2, PXN, RAB1A, PEAK1, FZD4, BVES, EFNA1, KIF14, TEK, TGFB1I1, NTN4, AKIP1, FZD7, SRGAP2, ITGB3, VAMP3, MEGF9, RAC1, ABL1, FER, PARVG, PARVB, PARVA, EPHA1, ITGB7, LAMB1, ILK, LAMB3, LAMC3, FERMT3, NRP1, LAMA5, EPHB3, RADIL, MERTK, MICALL2, SRCIN1, ITGA8, TYRO3 |
| substrate-dependent cell migration | biological process | CSPG4, ANKS1A, ITGA2, VEGFC, EPHA8, ITGA11, FMNL1 |
| substrate-dependent cell migration, cell attachment to substrate | biological process | EPB41L5, TNFRSF12A |
| substrate-dependent cell migration, cell extension | biological process | SHTN1, MYH10, NCK1, CTTN, NTN1, P2RY12, SDCBP, CD2AP, OPHN1, NRP1 |
| subtelomeric heterochromatin assembly | biological process | H3-3A |
| subthalamus development | biological process | UQCRQ |
| succinate metabolic process | biological process | SDHB, SDHA, SUCLA2, SUCLG2, SDHAF3, ALDH5A1 |
| succinate transmembrane transport | biological process | SLC13A3, SLC13A2, SLC13A1, SLC25A10, SLC13A5 |
| succinate transport | biological process | SLC13A3, SLC13A5 |
| succinyl-CoA metabolic process | biological process | OGDH, SUCLA2, SUCLG2, DLST, ACOT4 |
| succinyl-CoA pathway | biological process | SUCLA2 |
| suckling behavior | biological process | APP, OXTR, DERL2, GRIN1, UBE2Q1, CNTFR, PEX13, UBR3, DACH1, POU4F1, GLS, HAND2 |
| sucrose biosynthetic process | biological process | FBP1, FBP2 |
| sucrose metabolic process | biological process | GAA |
| sucrose transport | biological process | SLC45A2, SLC45A1, SLC45A4 |
| sulfate assimilation | biological process | TXNDC8, TXNDC2, SULT2B1, PAPSS2 |
| sulfate transmembrane transport | biological process | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC13A1, SLC26A2, SLC25A10, SLC26A11, SLC26A1, SLC26A10, SLC26A6 |
| sulfate transport | biological process | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC13A1, SLC26A2, SLC25A10, SLC26A11, SLC26A1, SLC26A10, SLC26A6 |
| sulfation | biological process | SULT1E1, SULT1A1, SULT2A1, CHSY1, SULT1C2, SULT1B1, SULT1C4, SULT1A3, SULT1A2 |
| sulfide oxidation, using sulfide:quinone oxidoreductase | biological process | ETHE1, SUOX, TSTD1, SLC25A10, SQOR |
| sulfur amino acid biosynthetic process | biological process | CDO1 |
| sulfur amino acid catabolic process | biological process | ADO, GADL1, TST, CTH, MPST, TXN2 |
| sulfur amino acid metabolic process | biological process | MTR, MTRR, BHMT2, AHCY, MAT1A |
| sulfur compound metabolic process | biological process | GAL3ST3, SULT4A1, SUOX, PAX8, CHST9, CHST6, CHST4, CHST5, CHST2, CHST3, ARSG, CHST8, GAL3ST4, CHST7 |
| sulfur oxidation | biological process | MICAL2, MICAL1 |
| superior olivary nucleus maturation | biological process | CDK5R1, CDK5R2 |
| superior temporal gyrus development | biological process | GSK3B, CNTNAP2 |
| superoxide anion generation | biological process | SOD1, NOX5, NOX1, CYBB, TAFA4, NOXA1, CYBA, NCF1, DUOX2, EDN1, DUOX1 |
| superoxide metabolic process | biological process | SOD1, SOD2, NOS2, CYBB, NQO1, NOXO1, NOXA1, CYBA, NCF1, IMMP2L, CYB5R4, NCF4, PREX1, SOD3, NRROS, SH3PXD2B, SH3PXD2A |
| suppression by virus of host apoptotic process | biological process | BAD, BCL2L1 |
| suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process | biological process | CASP8 |
| suppression by virus of host STAT1 activity | biological process | SCRIB |
| suppression by virus of host STAT2 activity | biological process | SCRIB |
| supramolecular fiber organization | biological process | LTBP2, SNCA, MFAP4, COL3A1, MFAP5, ILK, COL5A1, ADAMTS3 |
| surfactant homeostasis | biological process | VEGFA, ABCA12, EPAS1, SFTPD, LPCAT1, CTSH, NAPSA, ADGRF5 |
| susceptibility to natural killer cell mediated cytotoxicity | biological process | PVR |
| susceptibility to T cell mediated cytotoxicity | biological process | PVR |
| swimming | biological process | EP300 |
| swimming behavior | biological process | ALK, IDO1 |
| symmetric cell division | biological process | SAPCD2 |
| sympathetic ganglion development | biological process | CTNNB1, SEMA3A, SEMA3F, PHOX2B, FZD3, ASCL1, NRP2, INSM1, NRP1 |
| sympathetic nervous system development | biological process | SEMA3A, NTRK1, TP63, GDNF, PHOX2B, GATA3, ASCL1, SOX11, SOX4, PLXNA4, PHOX2A, GFRA3, NRP1, NF1, HAND2 |
| sympathetic neuron projection extension | biological process | SEMA3A, SEMA3F, NRP2, NRP1 |
| sympathetic neuron projection guidance | biological process | SEMA3A, SEMA3F, NRP2, NRP1 |
| synapse assembly | biological process | BDNF, PTEN, NRG1, CDH1, FLRT3, RYK, PCDHB9, RAB29, KIRREL3, GPM6A, GNPAT, NRXN1, SLC25A46, NLGN2, SPOCK2, PCDHB4, DNM3, NRXN2, PCDHB3, NRCAM, DBNL, SHANK2, ADGRF1, SLITRK1, BSN, SPTBN2, MECP2, SLITRK6, FARP1, ADD2, PCDHB14, DSCAM, SDK2, PCDHB16, PCDHB5, POU4F1, CDH9, PCDHB10, DRD1, FZD5, CDK5, DRD2, SDK1, PLXND1, SHANK1, DNER, CLSTN3, ADGRL3, CRKL, MAP1B, VPS35, PCDHB2 |
| synapse assembly involved in innervation | biological process | FBXO45 |
| synapse maturation | biological process | PTEN, BCAN, NFIA, CX3CR1, SEZ6L, PALM, SHANK1, SEZ6, IGSF21, NEFL |
| synapse organization | biological process | CTNNB1, SEMA3E, PPFIA1, GET1, NPTN, PIN1, NLGN4X, DVL1, PPFIA2, WNT7B, TSC1, LRRTM1, NLGN2, DRP2, MYO5A, SYN1, KLK8, CHRNA7, PSEN1, SLC8A3, NLGN4Y, CTNND2, PPFIBP2, NFASC, CBLN2, LRRC4, PPFIA3, PAK3, SLC9A6, PTPRS, C1QA, LMX1A, AGRN, LRRTM2, LRP4, ELFN1, L1CAM, PPFIA4, SLC8A2, WNT7A, GRM5, ADGRL3, PPFIBP1, SNCG |
| synapse pruning | biological process | C1QB, DKK1, C1QC, CX3CR1, EPHA4, CDK5, C1QA |
| synapsis | biological process | SPO11, REC8, MLH1, TEX15, STRA8, SPATA22, HORMAD1, MAEL, SYCP1, DMC1, MEIOB, KASH5, FANCD2, MRE11, CCNE1, TERB2, SIRT7, SIX6OS1, BRIP1, CCNE2, ANKRD31 |
| synaptic growth at neuromuscular junction | biological process | APP, SHANK2, LRP4, SHANK1 |
| synaptic membrane adhesion | biological process | LRFN4, LRFN5, PTPRF, IL1RAP, NTNG1, GPC6, EFNA5, LRRC4B, SLITRK1, NTNG2, LRRC4, CDH9, GPC4, SLITRK3, LRFN3, PTPRS, SLITRK2, IGSF9B, PTPRD, SPARCL1 |
| synaptic signaling | biological process | DTNB, DRP2, DTNA, KCMF1 |
| synaptic signaling via neuropeptide | biological process | PENK |
| synaptic target recognition | biological process | YWHAZ |
| synaptic transmission involved in micturition | biological process | CHRNA3, CHRNB2, CHRNB4 |
| synaptic transmission, cholinergic | biological process | APOE, CHRNA5, RAPSN, CHRNE, NQO1, RIC3, CHRNA2, ANXA9, CHRNB1, LYNX1, CHRM3, CHRNA7, CHRND, CHRFAM7A, CHRNA10, CHRNA3, CHRNA6, SLC5A7, CHRNG, CHRNB2, CHRNA4, ADORA2A, CHRNA1, CHRNB4 |
| synaptic transmission, dopaminergic | biological process | PARK7, RASD2, PRKN, CRH, CRHBP, DRD3, TH, DRD1, CDK5, DRD2, ADORA2A, DRD4 |
| synaptic transmission, GABAergic | biological process | GABRA2, GABRG2, GABRA5, GABRB2, GABRA4, GABRG1, RAC3, GABRA1, GABRA3, CLSTN3, GABRG3 |
| synaptic transmission, glutamatergic | biological process | ALS2, GRIN1, PRKN, SLC1A4, CNIH3, SLC17A6, GRIA2, GRIN2C, UNC13C, UNC13B, GRIK3, GRIK5, GRIN2B, NAPA, GRIN3A, GRID2, CDH8, GRIA3, CDK5, GRIK4, CNIH2, GRIN2A, GRIN3B, GRIA1, GRID1, UNC13A, ADORA2A, CLSTN3, GRIN2D, GRIK1, GRIK2, CDHR3, SHC3, NAPB, SLC17A7 |
| synaptic transmission, glycinergic | biological process | SLC6A20, GLRA3, GLRA1, SLC6A5, GLRA2 |
| synaptic vesicle budding | biological process | ARF1 |
| synaptic vesicle budding from endosome | biological process | AP3B1, AP3D1 |
| synaptic vesicle budding from presynaptic endocytic zone membrane | biological process | PICALM, DNM3, SNAP91, MX1, MX2, DNM1 |
| synaptic vesicle clustering | biological process | NRXN1, SYN1, SYN2, SYNDIG1, SYN3 |
| synaptic vesicle cycle | biological process | STXBP5, SYN1, SYN2, SYN3, BRSK1 |
| synaptic vesicle docking | biological process | STX3, CTBP2, SNPH, STX1B, SNAP25, UNC13C, UNC13B, BLOC1S6, PPFIA3, UNC13A |
| synaptic vesicle endocytosis | biological process | SYNJ1, CANX, NLGN4X, SNCA, KIAA1109, SH3GL2, DENND1A, SYNJ2, NLGN2, SYT1, PICALM, DNM3, RAB27B, SYT5, SNAP91, SYP, SCRIB, AMPH, NLGN4Y, AP2B1, ACTG1, FCHO2, STON1, OPHN1, ARF6, CDK5, DNM1, PIP5K1C, ITSN1, SYT2, STON2, PACSIN1, Grn |
| synaptic vesicle exocytosis | biological process | SNCA, RIMS1, SNAPIN, TRIM9, CPLX1, SYT1, SYT5, OTOF, CADPS, STX1B, DOC2A, SNAP25, UNC13C, CADPS2, UNC13B, DNAJC5, P2RX7, PPFIA3, CDK5, PIP5K1C, UNC13A, SYT2, SYT10, CPLX2, CPLX3 |
| synaptic vesicle fusion to presynaptic active zone membrane | biological process | PRRT2, SNAP23, SNAPIN, STX3, SNAP29, STX1B, SNAP25, SNAP47, STX4, STX11 |
| synaptic vesicle lumen acidification | biological process | SLC17A7 |
| synaptic vesicle maturation | biological process | SNAPIN, PICALM, SYP, UNC13C, UNC13B, DLG4, UNC13A |
| synaptic vesicle membrane organization | biological process | SYNGR1, AP3D1, SYP, SYNGR2 |
| synaptic vesicle priming | biological process | SYNJ1, SNAP23, SNCA, VAMP1, SNAP29, OTOF, SNAP25, UNC13C, CADPS2, UNC13B, SNAP47, NAPA, ERC2, UNC13A, SV2A |
| synaptic vesicle recycling | biological process | RAB5A, WNT3A, PLD2, SYT7, WNT7A, STON2 |
| synaptic vesicle targeting | biological process | SCRIB, PSEN1, SEPTIN5 |
| synaptic vesicle to endosome fusion | biological process | VAMP4, EEA1 |
| synaptic vesicle transport | biological process | CTNNB1, SYNJ1, KIF5B, RAB27A, SNAPIN, LIN7A, SPG11, KIF5A, CDK5 |
| synaptic vesicle uncoating | biological process | SYNJ1, SH3GL2, GAK, DNAJC6, SH3GL1 |
| synaptonemal complex assembly | biological process | BAG6, SPO11, REC8, TEX11, TEX15, MLH3, SYCE1, HORMAD1, SYCP1, STAG3, SYCE1L, AGO4, TRIP13, MEIOC, SYCE3, SYCP2, P3H4, TEX12, MCMDC2 |
| synaptonemal complex disassembly | biological process | HSPA2, PLK1 |
| synaptonemal complex organization | biological process | UBE2B, SYCE1, SYCE1L |
| synchronous neurotransmitter secretion | biological process | SYT1 |
| syncytiotrophoblast cell differentiation involved in labyrinthine layer development | biological process | CASP8, FZD5 |
| syncytium formation | biological process | ERCC1, ERVW-1, ERVFRD-1, ERVH48-1 |
| syncytium formation by plasma membrane fusion | biological process | VASH2, ERVW-1, ERVFRD-1 |
| T cell activation | biological process | TGFB1, IL6, CASP8, PRLR, HSPD1, CLEC7A, CD8A, RAB29, NCK1, PPP3CB, RASGRP1, NCK2, ITK, ZAP70, NEDD4, PTPRC, DDOST, SLA2, CD3E, SATB1, CD3G, DLG1, PPP3CA, DPP4, ADA, CD2, PIK3CG, TNFSF14, CD4, PIK3CD, WAS, TREML2, LAT, CD28, KIF13B, VAV1, ICOSLG, CARD11, CD8B, SMAD3, DOCK2, CD7 |
| T cell activation involved in immune response | biological process | IFNA1, CD74, CD1C, IFNA8, MDK, IFNA10, PSEN1, LCP1, IFNA2, IFNA14, IFNW1 |
| T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell | biological process | ICAM1, FGL2, ITGAL |
| T cell aggregation | biological process | ZAP70, MSN |
| T cell antigen processing and presentation | biological process | ICAM1, KDM5D, RFTN1, TREX1 |
| T cell apoptotic process | biological process | FASLG, BCL10, LMBR1L, KDELR1 |
| T cell chemotaxis | biological process | GPR183, SLC12A2, CXCL11, CCL3, CXCL16, CCL26, PIK3CG, CXCR3, DEFA4, DEFA1, PIK3CD, CXCL12, CXCL10 |
| T cell costimulation | biological process | HLA-DRB1, HLA-DPB1, HLA-DQB1, AKT1, HLA-DRA, MTOR, HLA-DQA1, YES1, SRC, PIK3CA, PDCD1, CDC42, PTPN11, PIK3R1, BTLA, GRAP2, PTPN6, MAP3K8, CTLA4, CD274, CD86, CD3E, TNFSF13B, GRB2, RAC1, DPP4, LYN, HHLA2, PDCD1LG2, TNFRSF14, CCL19, EFNB1, TNFSF14, PAK3, EFNB2, TNFRSF13C, EFNB3, CD160, LCK, CD28, VAV1, CSK, PDPK1, ICOSLG, CARD11, CD5, CCL21, CD80, CAV1 |
| T cell cytokine production | biological process | DLG1, SLC11A1, KDELR1 |
| T cell differentiation | biological process | TGFB1, BCL2, CTNNB1, LEP, LEPR, KIT, IL2, CHD7, PATZ1, PPP3CB, PTPN2, EGR1, ITPKB, SP3, GATA3, ZAP70, PTPN22, PTPRC, CD3E, CD3G, GPR89A, GPR89B, IL7R, SOX4, PKNOX1, LMBR1L, KDELR1, RUNX2, TBX21, CD4, PREX1, PIK3CD, LCK, TCIRG1, JAG2, VAV1, RHOH, LFNG, RAG2, NHEJ1 |
| T cell differentiation in thymus | biological process | BCL2, RAG1, LIG4, CTNNB1, B2M, SHH, GLI3, FZD8, STAT5B, RABL3, NCAPH2, WNT4, GATA3, FADD, BCL11B, NKAP, FZD7, CD3E, CDK6, ZFP36L2, PRKDC, MR1, ZFP36L1, RIPK3, FZD5, PRR7, TP53, RAG2, ZBTB1 |
| T cell differentiation involved in immune response | biological process | FCER1G, CLEC4D |
| T cell homeostasis | biological process | TGFB1, BCL2, RAG1, FAS, CCNB2, CASP3, IL2RA, ZC3H8, BCL2L11, STAT5B, PPP3CB, FOXN1, FADD, RC3H2, RC3H1, P2RX7, RIPK3, TNFSF14, NCKAP1L, SLC39A3, CORO1A, TCIRG1, SPNS2, JAK3, SLC46A2, SIT1 |
| T cell homeostatic proliferation | biological process | BAX |
| T cell lineage commitment | biological process | BCL2, IL7, FOXN1, PRKDC, TP53, RAG2 |
| T cell meandering migration | biological process | MYO1G |
| T cell mediated cytotoxicity | biological process | CTSC, EMP2, HPRT1, TSTA3, CRTAM, CTSH, GZMM |
| T cell mediated immunity | biological process | CD46, CD8A, GNL1, BTN3A2, BTN3A3, JAG1, MYO1G |
| T cell migration | biological process | CCL20, S1PR1, ZAP70, CCR6, MSN, ITGB7, MYO1G |
| T cell proliferation | biological process | IL23A, MALT1, PPP3CB, RASGRP1, CTPS1, CD151, RC3H2, PTPRC, TNFRSF4, MSN, RC3H1, RIPK2, FKBP1B, PIK3CG, LMBR1L, P2RX7, TNFSF14, EBI3, CCND3, DOCK2, PSMB10 |
| T cell proliferation involved in immune response | biological process | SLC11A1, TP53 |
| T cell receptor signaling pathway | biological process | IFNG, HLA-DRB1, HLA-DPB1, HLA-DQB1, MAPK1, HLA-DRA, PTEN, HLA-DQA1, PIK3CA, PSMA3, PTPRJ, MALT1, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, SKP1, PSMD6, ZC3H12A, PSMD1, PSMD14, BCL10, PIK3R1, PSMD7, BTRC, MAP3K7, NCK1, PSMB6, UBE2N, EIF2B3, PSMD10, PSMD8, PSMC5, EIF2B1, PSMB4, PSME1, CUL1, GRAP2, PSMB8, PSMD4, THEMIS2, CTLA4, PSMC3, BCAR1, PSMA6, ITK, STOML2, HLA-DQA2, GATA3, ZAP70, RELA, PRKCQ, MOG, WNK1, BTN3A1, NFKBIZ, RC3H2, PTPN22, PTPRC, TEC, PSEN1, SKAP1, ZNF683, PRAM1, CD3E, DENND1B, IKBKG, CD3G, BTN3A2, PDE4B, TAB2, PSMD12, CD247, PSMB9, PSMC4, RFTN1, RC3H1, FYB2, PSMD9, FYB1, RIPK2, ABL1, HLA-DPA1, PSMA4, PSMD2, RBCK1, TRAF6, PDE4D, BTNL9, HHLA2, EIF2B2, PSMD5, PSMF1, BTN3A3, PSMB3, LCP2, ERMAP, IKBKB, EIF2B5, PSMD3, PAK3, CD4, PSMC1, VTCN1, SPPL3, PRKD2, LIME1, PAG1, PIK3CD, TNFRSF21, HRAS, WAS, LAT, THY1, LCK, CD28, PIK3R2, CSK, CACNB3, PDPK1, ICOSLG, RNF31, CARD11, PLCG2, BTNL3, THEMIS, INPP5D, TXK, CRKL, TRAT1, EIF2B4, PSMD13, PSMB10, BTNL8 |
| T cell receptor V(D)J recombination | biological process | LIG4, TCF7, BCL11B, PRKDC, LEF1 |
| T cell secretory granule organization | biological process | SRGN |
| T cell selection | biological process | CD74, CD4 |
| T follicular helper cell differentiation | biological process | GPR183, FOXP1, RC3H2, RC3H1 |
| t-circle formation | biological process | ERCC1, SLX1A, SLX4, EXO1, SMARCAL1, BLM, XRCC3 |
| T-helper 1 cell activation | biological process | HMGB1, TCIRG1 |
| T-helper 1 cell cytokine production | biological process | IL18RAP |
| T-helper 1 cell differentiation | biological process | HMGB1, LEF1, RELB |
| T-helper 1 cell lineage commitment | biological process | IL4, SPN, STAT6 |
| T-helper 1 type immune response | biological process | HLA-DRB1, IL18, TLR4, BCL3, TRAF6, IL18BP, HRAS, RELB, EBI3 |
| T-helper 17 cell differentiation | biological process | BATF, RORA, RORC |
| T-helper 17 cell lineage commitment | biological process | IL6, BATF, SLAMF6, LY9 |
| T-helper 2 cell activation | biological process | TNFSF4 |
| T-helper 2 cell cytokine production | biological process | IL4, STARD7, DENND1B, IL31RA |
| T-helper 2 cell differentiation | biological process | IL4, BCL3, BATF, GATA3 |
| T-helper cell differentiation | biological process | PTGER4, ATP7A, RORC |
| T-helper cell lineage commitment | biological process | ZFPM1 |
| T-tubule organization | biological process | ATP2A2, CAV3, ANK2, CSRP3, SYPL2, MYOF, DYSF, BIN1 |
| tachykinin receptor signaling pathway | biological process | TAC3, TACR3, TAC1, GRK5, GRK2, TAC4, TACR2 |
| tail-anchored membrane protein insertion into ER membrane | biological process | BAG6, GET1, SGTA, GET3, GET4, UBL4A |
| tangential migration from the subventricular zone to the olfactory bulb | biological process | SLIT1, SRF, LRRK2 |
| targeting of mRNA for destruction involved in RNA interference | biological process | DICER1, TARBP2, CLP1 |
| tarsal gland development | biological process | ASH1L |
| taste bud development | biological process | NTF4 |
| taurine biosynthetic process | biological process | CSAD, CDO1 |
| taurine metabolic process | biological process | STAT5B, BAAT, GHR, PHGDH, STAT5A |
| taurine transport | biological process | SLC6A6, PHLPP2, LRRC28, LRRC8D, LRRC8C, LRRC8B, PHLPP1 |
| TDP phosphorylation | biological process | AK9 |
| tear secretion | biological process | FGF10 |
| telencephalon cell migration | biological process | CXCR4, SLIT1, FOXB1, CXCL12, NKX2-1 |
| telencephalon development | biological process | FAS, BMP4, OXTR, FGF8, EMX1, GLI3, ZDHHC16, TCTN1, HES1, SLC1A2, LHX1, SLC8A3, SIX3, SLC8A1, AVPR2, BMP2, CDK5, KAT2A, NRGN, SCN5A, LHX2, RPGRIP1L, NKX2-1 |
| telencephalon regionalization | biological process | BMP4, SHH, SIX3, BMP2, LHX2 |
| telomerase holoenzyme complex assembly | biological process | PTGES3, NAF1 |
| telomerase RNA localization to Cajal body | biological process | WRAP53 |
| telomerase RNA stabilization | biological process | DKC1, DHX36, PARN, NAF1 |
| telomere assembly | biological process | POT1, TINF2, ACD |
| telomere capping | biological process | HIST1H4A, TERF2IP, POT1, TINF2, DCLRE1B, PRKDC, ACD, RAD50, STN1, H4-16 |
| telomere formation via telomerase | biological process | WRAP53 |
| telomere localization | biological process | KASH5 |
| telomere maintenance | biological process | TERT, ATM, HSPA1A, PCNA, APEX1, NBN, TERF2IP, PTGES3, XRCC5, RPA2, RPA1, POT1, DCLRE1C, FBXO4, XRCC6, DCLRE1B, RTEL1, PARP3, MRE11, CCNE1, SP100, POLD2, PRKDC, HUS1, RPA3, ACD, RIF1, RAD50, ERCC4, RAD51D, BLM, HUS1B, STN1, POLD4, RECQL4, CCNE2, LTO1, POLD1, ZNF365 |
| telomere maintenance in response to DNA damage | biological process | RTEL1, RIF1 |
| telomere maintenance via recombination | biological process | BRCA2, PCNA, TEP1, NSMCE2, RAD51C, SMC5, RAD50, XRCC3 |
| telomere maintenance via semi-conservative replication | biological process | PRIM2, RPA2, RFC4, FEN1, POLE3, RFC5, RFC3, RPA1, UPF1, POLD2, RPA3, RFC2, POLE4, PRIM1, POLE, POLA2, POLD4, POLD1, RFC1, POLA1 |
| telomere maintenance via telomerase | biological process | TERT, ATM, TERF2IP, DKC1, PTGES3, NOP10, RPA1, POT1, NHP2, WRAP53, SMG7, MRE11, SMG6, RAD50, SMG5, PINX1, RFC1, TNKS1BP1, GAR1 |
| telomere maintenance via telomere lengthening | biological process | TERF2IP, SLX1A, DCLRE1B, STN1, ZBTB48, ZSCAN4 |
| telomere maintenance via telomere trimming | biological process | XRCC3 |
| telomere organization | biological process | HIST1H4A, DOT1L, H3C1, H3-3A, H4-16 |
| telomere tethering at nuclear periphery | biological process | NUP98 |
| telomeric 3' overhang formation | biological process | NBN, DCLRE1B, MRE11, RAD50 |
| telomeric D-loop disassembly | biological process | SLX1A, SLX4, POT1, BLM, RECQL4 |
| telomeric DNA-containing double minutes formation | biological process | ERCC4 |
| telomeric loop disassembly | biological process | RTEL1, XRCC3 |
| telomeric loop formation | biological process | DCLRE1B |
| temperature homeostasis | biological process | GPX1, STAT3, FOXO1, CIDEA, PPARGC1A, NMU, NAPEPLD, ACADVL, ACADL, ARRDC3, DRD1, HCRT, DRD2, NTSR1, TRPM2, TRPV1 |
| tendon cell differentiation | biological process | BMP4 |
| tendon development | biological process | COL11A1, COL5A1, COMP |
| terminal button organization | biological process | SNAPIN, NLGN2 |
| terminal web assembly | biological process | EZR, PLS1, VIL1 |
| termination of mitochondrial transcription | biological process | MTERF1, MTERF2 |
| termination of RNA polymerase I transcription | biological process | ERCC2, GTF2H3, POLR1F, POLR1B, POLR1H, POLR2F, CDK7, CCNH, POLR1C, TTF1, POLR1E, POLR1A, UBTF, TAF1C, TAF1B, TAF1A, POLR2L, POLR2E, GTF2H1, POLR2K, GTF2H4, TAF1D, MNAT1, POLR2H, CAVIN1, GTF2H5 |
| termination of RNA polymerase II transcription | biological process | SRSF4, SRSF9, SRSF6, CSTF2, CPSF2, NUDT21, PAPOLA, NCBP2, CSTF1, CPSF4, TTF2, PCF11, LSM11, SETX, CPSF3, NCBP1, ZNF473, MAZ, SNRPE, SNRPB, CPSF7, SNRPG, SLBP, SCAF8, CSTF3, SSU72, CPSF1, SNRPF, MED18, PABPN1, WDR33, SYMPK, CLP1 |
| termination of RNA polymerase III transcription | biological process | POLR3K |
| termination of signal transduction | biological process | GBA, SMPD1, PRKCD |
| terpene metabolic process | biological process | TH |
| tertiary branching involved in mammary gland duct morphogenesis | biological process | WNT4 |
| testosterone biosynthetic process | biological process | HSD17B1, HSD17B3, AKR1C3, STAR |
| tetracycline transmembrane transport | biological process | MFSD10 |
| tetrahydrobiopterin biosynthetic process | biological process | PTS, SPR, DHFR, QDPR, GCH1, PCBD1 |
| tetrahydrofolate biosynthetic process | biological process | GART, ATIC, DHFR2, DHFR, GCH1 |
| tetrahydrofolate interconversion | biological process | MTHFD1, MTHFR, TYMS, MTHFD2, SHMT1, MTHFD1L, FTCD, MTHFS, SHMT2, MTHFD2L |
| tetrahydrofolate metabolic process | biological process | MTHFR, TYMS, MTHFD2, SHMT1, DHFR2, MTHFS, SHMT2, DHFR, PIPOX |
| tetrahydrofolylpolyglutamate biosynthetic process | biological process | FPGS |
| tetrahydrofolylpolyglutamate metabolic process | biological process | GGH |
| tetrapyrrole biosynthetic process | biological process | HMBS, ALAD, UROS, ALAS1 |
| thalamus development | biological process | SRD5A1, SHH, PTN, LRP6, SMO, CNTNAP2, UQCRQ, PTCHD1, FOXB1, GBX2, TAL2 |
| thermoception | biological process | TRPA1, TRPV1 |
| thermosensory behavior | biological process | SLC12A5 |
| thiamine diphosphate biosynthetic process | biological process | TPK1 |
| thiamine diphosphate metabolic process | biological process | THTPA |
| thiamine import across plasma membrane | biological process | SLC22A2, SLC22A1 |
| thiamine metabolic process | biological process | ACPP, TKTL1, TPK1, THTPA |
| thiamine pyrophosphate transmembrane transport | biological process | SLC44A4, SLC25A19 |
| thiamine transmembrane transport | biological process | SLC19A3, SLC19A2, SLC25A19 |
| thiamine transport | biological process | SLC19A3, SLC35F3, SLC19A2 |
| thiamine-containing compound metabolic process | biological process | SLC19A3, TPK1, SLC19A2, THTPA, SLC25A19 |
| thigmotaxis | biological process | EP300, ID2 |
| thiocyanate metabolic process | biological process | LPO |
| thiosulfate transport | biological process | SLC25A10 |
| third ventricle development | biological process | MYH10, DPCD, C12orf57, ATP1B2 |
| thorax and anterior abdomen determination | biological process | WT1, NEUROG1, BASP1, TIFAB |
| threonine catabolic process | biological process | SDSL, GCAT, SDS |
| threonine metabolic process | biological process | PHGDH |
| threonine transport | biological process | SLC1A4 |
| threonyl-tRNA aminoacylation | biological process | TARS1, TARS2, TARS3 |
| thrombin-activated receptor signaling pathway | biological process | F2R, F2RL3, IQGAP2, PLEK, HPGD, F2RL2, GP1BA, DGKQ |
| thrombopoietin-mediated signaling pathway | biological process | CIB1, RBM15, SH2B3, MPL, THPO |
| thromboxane A2 signaling pathway | biological process | TBXA2R |
| thymic T cell selection | biological process | ITPKB, GATA3, ZAP70, JAG2, CARD11 |
| thymidine biosynthetic process | biological process | DHFR2, DTYMK |
| thymidine catabolic process | biological process | DPYD |
| thymidine metabolic process | biological process | TK2, TK1 |
| thymine catabolic process | biological process | DPYS, ALDH6A1, DPYD |
| thymine metabolic process | biological process | ALDH6A1 |
| thymine transport | biological process | SLC29A2 |
| thymocyte apoptotic process | biological process | BAX, BAK1, GLI3, BCL2L11, DFFA |
| thymocyte migration | biological process | CCL20, CCR6 |
| thymus development | biological process | SOD1, BCL2, RAG1, CCNB2, MAPK3, MAPK1, CTNNB1, RAF1, SHH, HOXA3, ASXL1, BCL2L11, ZMPSTE24, HES1, FOXN1, GATA3, FADD, JARID2, BCL11B, TYR, PSEN1, PBX1, PRKDC, MAD1L1, ABL1, PAX1, TGFBR1, SIX1, MAP2K1, SIX4, RIPK3, SRF, FOXE1, EPHB3, CRKL, FGF10, HAND2, SLC46A2, ZBTB1 |
| thymus epithelium morphogenesis | biological process | AIRE, FOXN1 |
| thyroid gland development | biological process | MAPK3, MAPK1, RAF1, FGF8, SHH, HOXA3, HOXD3, HOXA5, PAX8, SIX1, MAP2K1, SRF, FOXE1, HOXB3, NKX2-5, TG, THRA, SMAD3, FGF10, NKX2-1 |
| thyroid hormone catabolic process | biological process | DIO2, DIO3 |
| thyroid hormone generation | biological process | CTSK, CPQ, CTSB, TPO, SLC16A10, DIO2, DUOX2, FOXE1, DIO3, DUOX1, TG, SLC5A5, IYD |
| thyroid hormone mediated signaling pathway | biological process | THRA |
| thyroid hormone metabolic process | biological process | DIO2, SULT1B1, DIO3, TG, IYD |
| thyroid hormone transport | biological process | SERPINA7, SLC16A10, SLCO4A1, SLCO1C1 |
| thyroid-stimulating hormone secretion | biological process | SLC16A10 |
| thyroid-stimulating hormone signaling pathway | biological process | PAX8, TSHR |
| thyroid-stimulating hormone-secreting cell differentiation | biological process | FGF8, WNT4, BMP2 |
| Tie signaling pathway | biological process | TEK, ANGPT1, ANGPT2 |
| tight junction organization | biological process | CLDN9 |
| TIRAP-dependent toll-like receptor 4 signaling pathway | biological process | TIRAP |
| tissue development | biological process | NR5A2, WT1, NR5A1, BMP4, GAA, LAMC1, DHCR24, USH2A, NTNG1, NTN1, LAMC2, POSTN, NTN4, MEGF8, SALL4, FASN, MEGF9, NTNG2, TWSG1, HSPG2, MBD3, LAMB1, TMEFF1, EGFLAM, LAMB3, LAMC3, LAMA3, TMEFF2, LAMA5, NTN5, AGRN, NTN3, ATRNL1, DLL3, PTF1A |
| tissue homeostasis | biological process | SOX9, GNAS, ITGB1, AKR1B1, CCN2, CD34, COL2A1, TRIM32, ANKRD11, YAP1, BARD1, ACACA, PDGFRB, WWTR1, P2RX4, PRLH, CUBN |
| tissue morphogenesis | biological process | NODAL, SMAD4, DLG1, GCNT1 |
| tissue regeneration | biological process | CCNB1, SOX2, CPQ, IGFBP1, PTN, NINJ2, NOTCH1, MDK, APOD, TEC, CDKN1A, TM4SF4, APOA5, PLG, PTPN12, NINJ1, LGR6, KLK6, FGF10, GAP43 |
| tissue remodeling | biological process | IL23A, CSPG4, LIPA, MMP14, PLG, THBS4 |
| TNFSF11-mediated signaling pathway | biological process | CLDN18, TNFRSF11A, PIAS3 |
| tolerance induction | biological process | C3, CCR4 |
| tolerance induction to self antigen | biological process | TGFB1, LYN |
| Toll signaling pathway | biological process | PELI1, MYD88, TRAF3, PELI2, PELI3, PALM3 |
| toll-like receptor 1 signaling pathway | biological process | TLR1 |
| toll-like receptor 10 signaling pathway | biological process | TLR10 |
| toll-like receptor 2 signaling pathway | biological process | TLR2, LGALS9, IRAK1, PIK3AP1, RIPK2, TNIP2 |
| toll-like receptor 3 signaling pathway | biological process | COLEC12, HAVCR2, FADD, RFTN1, SCARA3, TNIP2, TLR3, UNC93B1, TICAM1 |
| toll-like receptor 4 signaling pathway | biological process | TLR4, TNIP3, LGALS9, LY96, IRAK1, PIK3AP1, ITGAM, NFKBIA, NR1H4, RIPK2, TICAM2, LYN, ITGB2, LBP |
| toll-like receptor 5 signaling pathway | biological process | TLR5 |
| toll-like receptor 6 signaling pathway | biological process | TLR6 |
| toll-like receptor 7 signaling pathway | biological process | PIK3AP1, HAVCR2, TLR7, UNC93B1 |
| toll-like receptor 9 signaling pathway | biological process | IRAK1, MYD88, IRAK2, PIK3AP1, HAVCR2, PIK3C3, NR1H4, TRAF6, PIK3R4, TLR9, TNIP2, TLR7, UNC93B1, IRAK4 |
| toll-like receptor signaling pathway | biological process | TLR4, TLR2, CTSK, BCL10, LY96, CTSL, CTSB, HSP90B1, IRAK1, MYD88, IRAK2, TRAF3, LGMN, FGG, TLR1, TLR10, FGB, HMGB1, LRRC19, TRAF6, S100A8, CTSS, MAPKAPK3, CNPY3, TLR9, SFTPD, TLR7, FGA, TLR3, TLR5, LBP, UNC93B1, TLR6, IRAK4, CD36, S100A1 |
| toll-like receptor TLR1:TLR2 signaling pathway | biological process | TLR2, TLR1 |
| toll-like receptor TLR6:TLR2 signaling pathway | biological process | TLR2, TLR6, CD36 |
| tongue development | biological process | GLI3, WNT10A, LEF1, SIX1, SIX4, PRDM16, HAND2 |
| tongue morphogenesis | biological process | BMP4, CYP26B1, INTU, HOXC13 |
| tonic smooth muscle contraction | biological process | MYLK |
| tooth eruption | biological process | ADAMTS1, SNX10, FAM20A, TCIRG1 |
| tooth mineralization | biological process | TSPEAR |
| TOR signaling | biological process | MTOR, RPS6, RPS6KB2, RPS6KB1, EIF4EBP2, CCDC88A, DISC1, GATA3, EIF4EBP1, MEAK7, TIPRL, LARP1, FNIP1, FLCN, MLST8, RPTOR, RHEBL1 |
| TORC1 signaling | biological process | MFSD8, LARP1, MLST8, NPRL3, RPTOR, CARD11 |
| TORC2 signaling | biological process | SESN3, PINK1, PRR5L, MAPKAP1, SYAP1, PRR5 |
| toxin biosynthetic process | biological process | CYP1A2 |
| toxin metabolic process | biological process | CYP1A1, CYP1A2, CYP1B1, PAM, ARL1, N6AMT1, FMO1 |
| toxin transport | biological process | CASP1, HSPA5, CCT5, CCT4, ANTXR1, CCT7, RAB29, SLC22A2, CCT6B, SLC17A3, COPB2, COPZ1, CCT2, TCP1, SCFD1, CCT3, DNAJC17, ABCG1, ANTXR2, RAB40B, CD274, SLC7A8, LRP6, ANTXRL, CCT8, BNIP3, RAB28, MTMR12, TRIP4, ARID1A, LRP5, GGA1, NRP1, HRH2, DNM1, SLC22A1, SLC22A3, ATP6V0A1 |
| trabecular meshwork development | biological process | CYP1B1, FOXE3 |
| trachea cartilage development | biological process | SOX9, SRF, RARG, RARA |
| trachea cartilage morphogenesis | biological process | HOXA5, WNT7B, LRP6, RSPO2 |
| trachea development | biological process | BMP4, SHH, HYDIN, FOXF1 |
| trachea formation | biological process | MAPK3, MAPK1, CTNNB1, BMP4, MAP2K1, TGFBR2 |
| trachea gland development | biological process | LEF1, EDA |
| trachea morphogenesis | biological process | CTNNB1, SHH, HOXA5, TGFBR2 |
| TRAF-mediated signal transduction | biological process | LRRC19 |
| TRAIL-activated apoptotic signaling pathway | biological process | CASP8, TNFRSF10C, TNFRSF10B, FADD, ZDHHC3, TNFRSF10A |
| TRAM-dependent toll-like receptor 4 signaling pathway | biological process | RAB11FIP2, TICAM2, PRKCE |
| trans-Golgi network membrane organization | biological process | AZIN2 |
| trans-synaptic signaling by BDNF, modulating synaptic transmission | biological process | NTRK2, PLG |
| trans-synaptic signaling by endocannabinoid, modulating synaptic transmission | biological process | CNR1, GRM5 |
| trans-synaptic signaling by neuropeptide, modulating synaptic transmission | biological process | NTRK2 |
| trans-synaptic signaling by nitric oxide, modulating synaptic transmission | biological process | GUCY1B1 |
| trans-synaptic signaling by trans-synaptic complex | biological process | IL1RAP, PTPRD |
| trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission | biological process | NPTN, EPHB2, EFNB3 |
| trans-synaptic signaling, modulating synaptic transmission | biological process | CSPG5 |
| transcription by RNA polymerase I | biological process | POLR1C, UBTF, TAF1C, TAF1B, TAF1A, POLR2L, GTF2H1 |
| transcription by RNA polymerase III | biological process | RO60, GTF3A, POLR3F, IVNS1ABP, GTF3C6, POLR1C, POLR3K, POLR3H, GTF3C3, SNAPC4, POLR2K, SNAPC3, GTF3C1, POLR3GL, POLR3D, GTF3C2, ZNF345, BRF1, SNAPC2, GTF3C5, CRCP, GTF3C4 |
| transcription elongation from mitochondrial promoter | biological process | TEFM |
| transcription elongation from RNA polymerase I promoter | biological process | ERCC2, GTF2H3, POLR1F, POLR1B, POLR1H, POLR2F, CDK7, CCNH, POLR1C, ERCC6, POLR1E, POLR1A, UBTF, TAF1C, TAF1B, TAF1A, POLR2L, POLR2E, GTF2H1, POLR2K, GTF2H4, TAF1D, MNAT1, POLR2H, GTF2H5 |
| transcription elongation from RNA polymerase II promoter | biological process | ERCC2, CDK9, TAF4B, SUPT4H1, MLLT1, GTF2H3, ELOC, NCBP2, POLR2F, ENY2, SUPT16H, CDK7, ELP2, NELFCD, WDR61, CCNH, POLR2G, NELFA, ELL2, CCNT1, GTF2F1, ELL, PAF1, ELP4, NCBP1, ELL3, POLR2B, PCID2, RTF1, IWS1, SUPT5H, POLR2D, NELFE, CTR9, ELOA2, CDC73, MLLT3, POLR2J, POLR2L, CDK13, ADRM1, CCNK, POLR2E, ELOB, TCEA1, GTF2H1, PBRM1, POLR2K, ELOF1, POLR2I, GTF2F2, ELOA3, SSRP1, GTF2H4, POLR2C, ELOA, MNAT1, LEO1, NELFB, POLR2H, POLR2A, CTDP1, EAF2, EAF1, GTF2H5 |
| transcription factor catabolic process | biological process | TAF1 |
| transcription from RNA polymerase II promoter | biological process | NR5A2, ESR1, TP53, ATF3, WT1, AHR, SOX9, SOX10, NR5A1, HIF1A, ZEB2, ERCC2, HNF1A, HSF2, NFE2L2, CTCFL, ARNT2, MBD1, PLAGL1, DMRT1, NR3C1, PARP1, STAT3, BMPR2, SOHLH1, EBF2, PROP1, OTX1, GATA4, SOX2, CDK9, MEF2A, CLOCK, USF1, SOX5, ETV5, TAF4B, TP63, SOHLH2, GTF2A1L, MYC, RBMX, TBPL1, FOXM1, PATZ1, YBX2, SUPT4H1, MLLT1, GTF2H3, TFDP1, ELOC, MED4, TRIM24, KLF4, RNGTT, BTF3, NCBP2, GTF2A2, POLR2F, TAF5, TAF12, TBPL2, ZNF768, SUPT16H, PIR, CDK7, NELFCD, WDR61, HIF3A, FAM170A, CCNH, POLR2G, DR1, NFX1, NELFA, SCAF1, TAF9B, CCNT1, XBP1, GTF2F1, DEK, SUPT3H, ELL, ERCC6, TSC22D1, PAF1, DDX21, TCFL5, FOSB, NKX3-2, GTF2B, NCBP1, ZNF141, ELL3, POLR2B, YBX1, CBFB, TRIP13, RTF1, IWS1, SUPT5H, POLR2D, GCM2, NELFE, IRF9, NFIX, TAF13, TAF7, RNMT, COPS2, TAF11, TAF1C, CTR9, ELOA2, RPAP1, DEAF1, MAF, ATF4, PDX1, TAF1A, TAF3, DTX1, PHRF1, SNAPC5, NFIC, ETS1, LHX1, CDC73, MLLT3, POLR2J, POLR2L, NFRKB, TAF15, TAF5L, CCNK, POLR2E, TAF1, GTF2A1, PAX5, ELOB, TRIP11, SNAPC4, GTF2IRD1, TCEA1, NFYA, GTF2H1, EGR2, POLR2K, TAF2, EHF, NFAT |
| transcription initiation from mitochondrial promoter | biological process | TFB2M, POLRMT, TFAM |
| transcription initiation from RNA polymerase I promoter | biological process | ERCC2, MAPK3, GTF2H3, POLR1F, POLR1B, POLR1H, POLR2F, CDK7, CCNH, POLR1C, POLR1E, POLR1A, UBTF, TAF1C, TAF1B, TAF1A, POLR2L, POLR2E, TAF1, GTF2H1, RRN3, POLR2K, GTF2H4, TAF1D, MNAT1, POLR2H, CAVIN1, GTF2H5 |
| transcription initiation from RNA polymerase II promoter | biological process | NR5A2, ESR1, PGR, AR, VDR, NR5A1, ESR2, NR1I2, ERCC2, NR0B1, NR3C1, THRB, PPARG, CDK9, TAF7L, NR1H3, TAF4B, GTF2A1L, MED7, CCNC, CCN2, GTF2H3, NR1D2, MED4, NRBP1, GTF2A2, POLR2F, TAF5, TAF12, MED8, CDK7, ESRRG, RARB, CCNH, POLR2G, HNF4G, TAF9B, GTF2F1, PPARD, GTF2B, CREBBP, PPARGC1A, POLR2B, MAZ, CBFB, POLR2D, CCND1, NOTCH1, TAF13, TAF7, MED10, E2F3, TAF11, MED14, MED6, RORA, TAF3, MED13, NR2E3, NR2F6, NR4A2, E2F2, MED23, MED31, TAF6L, POLR2J, POLR2L, MED25, TAF15, POLR2E, TAF1, MECP2, GTF2A1, NR1H4, TBX5, GTF2H1, TEAD2, MED26, NR2C1, TEAD1, POLR2K, RBPJ, TAF2, NRBF2, POLR2I, TAF6, SNW1, MED30, TAF4, GTF2F2, YAP1, TAF10, MAML2, ESRRA, NR1D1, CDKN1A, NOTCH4, NOTCH3, MED16, HNF4A, RUNX2, GTF2H4, MED12, MED15, POLR2C, MNAT1, TEAD4, WWTR1, NR2F1, RXRG, POLR2H, NR4A3, RARG, GTF2E2, KAT2B, NR4A1, POLR2A, PPARA, MED24, THRA, RORC, NR2C2AP, TEAD3, ESRRB, NR3C2, GTF2I, MED27, MAML1, GTF2E1, TAF9, MAML3, RARA, NR2C2, NR1H2, GTF2H5 |
| transcription initiation from RNA polymerase III promoter | biological process | POLR3H, SNAPC5, GTF3C1, BRF1, GTF3C5, CRCP, GTF3C4 |
| transcription open complex formation at RNA polymerase II promoter | biological process | GTF2E1 |
| transcription preinitiation complex assembly | biological process | GTF2B, BRF2, BRF1 |
| transcription, DNA-templated | biological process | NR5A2, ESR1, TP53, PGR, AR, VDR, ATF3, WT1, BRD2, AHR, BRCA1, SOX9, NRIP1, SOX10, NR5A1, HIF1A, ESR2, BIRC5, ZEB2, NR1I2, ERBB2, SP1, ERCC2, HNF1A, DNMT1, MAPK3, MAPK1, HNF1B, SOX3, STAT1, FASLG, NR0B1, HSF1, E2F1, HSF2, SRY, KANK1, STAT4, EZH2, NFE2L2, BRDT, CDKN2A, CTCFL, MBD3L1, PEG3, ARNT2, BRWD1, MBD2, MBD1, PLAGL1, DMRT1, CHD2, NR3C1, ENO1, PARP1, FGFR1, CSNK2A2, CTNNB1, STAT3, LBX2, DMRT2, ZFP37, KAT7, LTF, RB1, C1QBP, KHDRBS1, NCOA2, SOHLH1, ESX1, EBF2, XAB2, THRB, MAK, NR2F2, APEX1, PPARG, GATA4, SOX2, CDK9, MEF2A, FOXO1, TAF7L, STRA8, HSFY1, ZNF331, CHD7, CLOCK, BRD4, USF1, SOX5, KDM5C, CREM, NR1H3, TAF4B, DPF3, TADA1, PRMT6, SIN3A, NPAS2, ZMYND15, TP63, TCF7L2, PRDM9, SOHLH2, GTF2A1L, WASL, IL33, MYC, MYCN, RBMX, YLPM1, TBPL1, DYNLL1, FOXM1, ZNF174, MAPK14, TGIF2LY, TGIF2LX, PATZ1, ZNF230, PWP1, POLR1F, POLR1B, POLR1H, KLF4, POLR2F, PHF3, DRG1, MLF1, CNOT8, HOXD3, RFX3, CCNH, POLR2G, ASXL2, GPBP1, ASXL1, THAP1, CCNT1, BCL3, POLR1C, CREB3, POLR1E, GPBP1L1, PPP1R1B, HOXB9, POLR2B, HIRA, SMARCD3, POLR |
| transcription, RNA-templated | biological process | TERT, POLR2A |
| transcription-coupled nucleotide-excision repair | biological process | ERCC1, ERCC2, XRCC1, XPA, XAB2, PCNA, HMGN1, GTF2H3, COPS5, POLR2F, COPS8, RPA2, RFC4, CDK7, PRPF19, CCNH, POLR2G, COPS6, RFC5, RFC3, RPS27A, ERCC6, COPS4, RPA1, POLK, POLR2B, UVSSA, POLR2D, ERCC5, ERCC8, COPS2, ZNF830, AQR, POLR2J, POLR2L, POLR2E, EP300, TCEA1, GTF2H1, POLD2, POLR2K, USP7, UBC, RPA3, POLR2I, UBA52, ERCC4, ISY1, LIG1, RFC2, GTF2H4, PPIE, POLR2C, LIG3, RBX1, COPS7B, POLD4, MNAT1, GPS1, COPS7A, POLR2H, UBB, POLR2A, POLD1, RFC1, DDB1, GTF2H5 |
| transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | biological process | NUP155, RAE1, NUP133, LDB1 |
| transcriptional activation by promoter-enhancer looping | biological process | RUVBL2, NIPBL, ZFPM1, GATA1 |
| transcriptional start site selection at RNA polymerase II promoter | biological process | GTF2B |
| transcytosis | biological process | SRC, USO1, GPIHBP1, LRP2, MAL2, MFSD2A, LRP1, PTAFR, RAB17, VPS35, AGER |
| transdifferentiation | biological process | LIF, GATA4, CD34, PDX1, GOT1, INSM1, SMAD3 |
| transepithelial ammonium transport | biological process | SLC12A2, RHBG, RHCG |
| transepithelial chloride transport | biological process | P2RY4, SLC12A2, P2RY6, SLC26A6 |
| transepithelial L-ascorbic acid transport | biological process | SLC23A1, SLC23A2 |
| transepithelial transport | biological process | SLC1A2, SLC1A3, GPLD1, CXADR, SLC26A6, ABCG2 |
| transepithelial water transport | biological process | AQP1, SLC5A1 |
| transferrin transport | biological process | ATP6V0A2, TF, LMTK2, ATP6V1B1, ATP6V1D, ATP6V1G1, ATP6V1B2, TFRC, ATP6V1E1, ATP6V0E1, ATP6V1G2, ATP6V1A, ATP6V1G3, RAB11B, ARHGAP1, ATP6V0E2, ATP6V1C1, CLTC, ATP6V1H, ATP6V0D1, ATP6V0B, ATP6V0A4, TFR2, ATP6AP1, STEAP3, ATP6V1F, TCIRG1, ATP6V1E2, ATP6V0C, MCOLN1, ATP6V1C2, ATP6V0A1 |
| transformation of host cell by virus | biological process | INSR, HYAL2 |
| transforming growth factor beta activation | biological process | LTBP3 |
| transforming growth factor beta receptor complex assembly | biological process | TGFBR3 |
| transforming growth factor beta receptor signaling pathway | biological process | USP9Y, TGFB1, FSHB, TGFB3, AMHR2, ITGB1, PARP1, TGFBR3, GDF15, GDF9, SRC, SKIL, LTBP2, FNTA, BAMBI, FERMT2, DUSP22, PXN, SMAD4, DUSP15, MAP3K7, PIAS2, ITGB5, RPS27A, MTMR4, CLDN5, ACVR1, PTK2, ZMIZ1, COL3A1, BMPR1A, TAB1, CITED1, SKI, HPGD, TGFB1I1, GCNT2, PARD3, FUT8, SMAD6, APOA1, COL1A2, TGFB2, LRRC32, HIPK2, NLK, LEFTY1, CBL, ADAM9, TWSG1, F11R, UBC, PML, TGFBR1, PRKCZ, PARD6A, UBA52, SMAD2, USP9X, FOS, APPL2, USP15, WFIKKN2, CDH5, TGFBR2, TGFBRAP1, LTBP3, MSTN, NRROS, ENG, ACVRL1, CGN, APPL1, FURIN, UBB, ARRB2, ARHGEF18, LEFTY2, SMAD9, LTBP4, ZMIZ2, SMAD3, FOXH1, ZFYVE9, SMAD5, TP53, GDF5, ZYX |
| transforming growth factor beta receptor signaling pathway involved in primitive streak formation | biological process | NODAL |
| transforming growth factor beta1 activation | biological process | NRROS |
| transforming growth factor-beta secretion | biological process | ITGB6 |
| transition between fast and slow fiber | biological process | MYH7, ATP2A2, PPP3CA, ACTN3, TNNT1, TNNI1, GTF2IRD2B |
| transition between slow and fast fiber | biological process | GTF2IRD1 |
| transitional one stage B cell differentiation | biological process | ABL1 |
| translation | biological process | AKT1, EIF3H, DENR, MRPS14, FARS2, EEF1G, RPL4, RPL3, EIF2D, RPL5, RPS10, EIF3E, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, EEF1A1, MRPS15, RPL24, RPL6, NACA, COPS5, RPL10L, GFM1, MRPL20, MRPL47, MRPL17, MRPL22, RSL24D1, MCTS1, EIF1AY, EIF3D, RPLP0, MRPL3, GSPT1, RPL29, RPL15, RPS8, RPL7A, ETF1, RPL32, RPS21, EIF4G2, MRPS11, MRPS21, MRPS9, KARS1, MRPL16, EIF3K, EIF3L, MRPS23, EIF3F, NARS1, RPL7, EIF2S2, RPL13, MARS1, RPS18, RPS13, RPL11, RPL19, EIF4A2, MRPL14, EIF3M, MRPL43, RPL39L, RPS6KB2, MRPS17, EPRS1, RPL35A, IARS1, EIF1, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, AIMP2, MRPL49, RPS27L, SRBD1, EIF2A, MRPS30, MRPS18A, MRPL15, EEF1E1, EIF3G, EIF3J, RPS2, RPL9, RPS19, EIF2S3, RPS5, MRPL19, YARS1, RPS25, RPL30, RPS27A, RPL38, RACK1, MRPL58, MRPL51, EIF2B3, MRPL35, MRPL27, HARS1, RPS3, RPL13A, RPL35, CARS1, RARS1, EIF5A, EIF4EBP2, EIF3A, EIF2B1, DARS2, GSPT2, RPL36AL, EIF5A2, SARS2, IARS2, MTRF1L, MRPS7, MRPS18C, MTRF1, RPLP1, WARS1, RPS12, RPS27, HARS2, EIF4A1, RPL39, MRPL10, MRRF, RPS4Y1, TARS1, RPL8, GCN |
| translation reinitiation | biological process | DENR, MCTS1, EIF3A |
| translational attenuation | biological process | YBX2, TRAP1 |
| translational elongation | biological process | EEF1G, EEF1A1, GFM1, EEF2K, EIF5A, EIF5A2, RPLP1, GTPBP1, EEF2, EFL1, EEF1D, EEF1A2, GFM2, TSFM, RPLP2, TUFM, EEF1B2, EEFSEC, ABTB1, GTPBP2 |
| translational initiation | biological process | DDX3Y, PABPC1, EIF3H, DENR, RPL4, RPL3, EIF2D, RPL5, RPS10, EIF3E, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, RPL24, RPL6, COPS5, PAIP1, MCTS1, DDX3X, EIF1AY, EIF3D, RPLP0, RPL29, RPL15, RPS8, RPL7A, RPL32, RPS21, EIF4G2, EIF3K, EIF3L, EIF3F, RPL7, EIF2S2, RPL13, RPS18, RPS13, RPL11, RPL19, EIF4A2, EIF3M, RPL35A, EIF1, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, EIF2A, EIF3G, EIF3J, RPS2, RPL9, RPS19, EIF2S3, RPS5, RPS25, RPL30, RPS27A, RPL38, EIF2B3, RPS3, RPL13A, RPL35, EIF3A, EIF2B1, RPLP1, RPS12, RPS27, EIF4A1, RPL39, EIF1AD, RPS4Y1, RPL8, EIF3B, EIF5, DHX29, MTIF3, MTFMT, RPL27A, RPL18A, EIF4E, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, EIF3C, EIF4E2, EIF5B, EIF4B, RPL14, RPL37, RPS15A, RPS24, RPS28, RPL36, EIF2S1, RPL10, AGO2, RPLP2, RPS17, RPL23A, RPL18, LARP1, EIF4E3, EIF1B, EIF1AX, EIF2B2, UBA52, RPSA, EIF6, RPS11, RPL36A, EIF2B5, ABCF1, RPL17, RPL23, RPL26, EIF3I, LTO1, DHX33, EIF2B4, EIF4H |
| translational termination | biological process | ETF1, MRPL58, MTRF1L, MTRF1, APEH, C12orf65, N6AMT1 |
| translesion synthesis | biological process | PCNA, KIAA0101, REV1, REV3L, POLH, RPA2, RFC4, TRIM25, RFC5, RFC3, RPS27A, DTL, RPA1, FAAP20, POLK, ISG15, POLD2, POLI, UBC, RPA3, UBE2L6, UBA52, RFC2, SPRTN, POLD4, USP10, UBB, POLD1, PARP10, USP43, POLN, PRIMPOL, RFC1, ZBTB1 |
| translocation of peptides or proteins into host cell cytoplasm | biological process | TCP1 |
| transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | AMHR2, AKAP4, BMPR2, MAPK14, LTBP1, ACVR1B, ACVR1, BMPR1A, ACVR2B, PPM1L, ACVR1C, TGFBR1, ACVR2A, TGFBR2, ACVRL1, GDF5 |
| transmembrane receptor protein tyrosine kinase signaling pathway | biological process | EGFR, ERBB2, FLT1, TYK2, KDR, INSR, YES1, IGF1R, KIT, NRG1, NGF, NTRK1, DDR1, CD8A, CSF1, RYK, ROR1, SH2B3, SHC1, BDKRB2, ALK, LTK, EPHB2, TIE1, AHI1, STAP1, FLT4, CSPG4, CNKSR1, NTF4, ROS1, BCAR1, RASGRP4, PILRB, PTPRG, TEK, NTRK2, PTPRT, MTSS1, EPHB1, SRMS, RAPGEF1, EPHA6, GAB2, ANGPTL1, CD3E, NEDD9, ANGPT1, TNK1, SHC4, FER, ABI1, LYN, FRS2, EPHA4, EPHA1, LCP2, MPZL1, FGR, ERBB3, TRADD, NRTN, CD4, RET, PDGFRB, EPHA2, SLA, EPHA7, EFS, DOK2, HCK, MST1R, SH2D6, LCK, PDGFRA, NTF3, EPHA3, EPHA8, IL31RA, DOK1, FGFR4, FRK, GFRA2, FES, CSF1R, INSRR, EPHB3, EPHB4, SHC2, ROR2, PTK6, EPHA10, DOK5, MERTK, CLNK, CD8B, SHC3, CD7, TRAT1, EPHB6, BLK, TYRO3 |
| transmembrane receptor protein tyrosine phosphatase signaling pathway | biological process | PTPRF, PTN, FRS2, PTPRU, TRIO, PTPRD |
| transmembrane transport | biological process | BCL2, CATSPER1, CATSPER2, ABCB1, CFTR, ABCC1, VDAC2, SLC22A18, SLC6A14, GJA1, SLC13A3, SLC6A20, SLC16A7, SLC22A5, PIP, AZGP1, CLCN2, CATSPER4, CATSPER3, SLC26A8, PRF1, VDAC1, SLC19A1, SLC6A8, CACNA1S, SLC26A4, SLC35E2B, PSMB1, SLC2A5, PSMB5, PSMC2, PEX19, SLC26A3, AQP2, KCNAB1, TMEM241, GJC2, SLC5A8, PSMA8, SLC35B3, FLVCR2, PSMA7, ERLIN1, SLC2A3, SLC25A4, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, SLC35B1, SLC30A9, SLC49A3, GPR155, SLC30A5, PSMB7, KCNH6, CNNM2, SCN11A, SLC22A2, EIF2S2, SLC6A2, SLC12A2, PSMD6, SLC44A4, SLCO6A1, SLC15A4, PSMD1, SLC25A13, GJD2, SLC17A3, PSMD14, SLC16A5, PSMD7, SLC14A1, TRPC3, ABCC10, SLC44A3, SLC44A5, SLC25A43, SLC44A1, DERL1, SLCO1B3, FLVCR1, PSMB6, CLCN1, EIF2S3, RPS27A, RALBP1, CACNA1E, CNGA2, SLC25A48, SLC24A5, SLC24A4, MFSD14A, PANX3, SLC19A3, KCNH3, KCNH4, CTNS, PSMD10, KCNA4, PSMD8, CLCNKA, PSMC5, KCNH2, ANO6, ABCA12, SLC22A15, AQP11, SLC22A12, SLC25A18, SLC25A22, SLC39A9, KCND3, SLC4A7, SLC22A23, RYR1, PSMB4, CLCN7, ABCA4, TAP1, PSME1, SLC15A2, SLC35F1, MFSD4B, SLC35D2, SLC22A9, |
| transmission of nerve impulse | biological process | SOD1, CACNG2, JAM3, CACNG3, S1PR1, CNTNAP2, DMRT3, NFASC, CACNG4, DRD1, CHRM5, MAG, SPTBN4, CACNG8, OTOA |
| transport | biological process | APOE, AR, FMR1, CATSPER1, CATSPER2, APOB, ABCB1, CFTR, AKT1, ATP6V0A2, ALB, TF, PAEP, ABCC1, AFM, VDAC2, BAG6, CLCA4, HFE, LTF, SERPINA5, IGF2R, PTGDS, CACNA2D1, SLC7A5, SLC22A18, KCNK9, SLC6A14, GJA1, AQP5, SLC13A3, KCNK17, SLC6A20, KCNK4, DDX25, SLC16A7, SLC22A5, MT-ATP6, MT-ATP8, LCN1, CLCN2, DYNLT1, CATSPER4, CATSPER3, SLC26A8, AQP7, GC, VDAC1, SLC19A1, SLC6A8, AGFG1, DYNLL1, CACNA1S, DYNC1H1, NXF2, GOPC |
| transport across blood-brain barrier | biological process | SLC28A2, SLC2A3, SLC6A6, SLC22A2, SLC12A2, SLC1A5, SLC44A1, SLC9A3R1, TFRC, SLC1A2, SLC15A2, SLC38A1, ABCC3, SLC1A4, SLC7A3, SLC4A4, SLC2A10, SLC1A3, SLC27A1, SLC7A8, ATP1A4, SLC38A2, ABCC9, SLC2A13, ATP1A2, LRP2, SLC29A2, MFSD2A, SLC7A1, ATP8A1, SLC2A4, ATP2A3, SLC24A3, SLCO2B1, AVPR1B, LRP1, SLC5A1, SLC5A6, ATP1B2, SLC16A1, SLC4A8, SLC6A9, KCNJ8, ABCC5, SLC27A4, SLC16A12, SLC29A1, LRP3, ABCA2, ABCC4, SLC4A3, SLC22A8, SLC38A5, SLC5A5, SLC38A3, SLC6A13, SLC8A2, SLC22A1, SLC22A3, SLCO1C1, SLCO3A1, SLC7A2, ABCG2, AGER, SLC6A17 |
| transport along microtubule | biological process | DYNC1I1, DYNC1I2, KIF1B, WDR60 |
| transport of viral material towards nucleus | biological process | DYNLT1 |
| transposition | biological process | PGBD5 |
| transposition, DNA-mediated | biological process | THAP10, THAP9 |
| transposition, RNA-mediated | biological process | L1TD1, TREX1 |
| transsulfuration | biological process | MTHFD1, CBS, TST, CTH, MPST |
| traversing start control point of mitotic cell cycle | biological process | MDM2, CDC6, MTBP |
| trehalose catabolic process | biological process | TREH |
| trehalose metabolic process | biological process | TREH |
| trehalose metabolism in response to stress | biological process | BRAF |
| tricarboxylic acid cycle | biological process | IDH1, SDHB, SDHA, PDHA1, MDH2, MDH1, OGDH, SUCLG1, SUCLA2, IREB2, ACO2, NNT, SDHD, SUCLG2, SDHAF2, IDH3B, PDHB, IDH2, FH, IDH3G, MDH1B, CS, IDH3A, SDHC, FAHD1, OGDHL, ME2, ME3, DLAT, ACO1, DHTKD1, DLST |
| tricarboxylic acid metabolic process | biological process | GLUD1, SIRT4, SLC34A1 |
| tricarboxylic acid transmembrane transport | biological process | SLC13A5 |
| tricarboxylic acid transport | biological process | SLC13A5 |
| tricellular tight junction assembly | biological process | LSR |
| tricuspid valve development | biological process | TBX20 |
| tricuspid valve formation | biological process | HEY2, ZFPM1 |
| tricuspid valve morphogenesis | biological process | BMPR1A, HEY2, TGFBR2 |
| TRIF-dependent toll-like receptor signaling pathway | biological process | CASP8, TLR4, UBE2D3, TBK1, LY96, RPS27A, TRAF3, FADD, IKBKE, TANK, BIRC2, IKBKG, TICAM2, UBC, UBE2D1, UBA52, IKBKB, CD300LF, IRF7, TLR3, UBB, IRF3, CD40, TLR6, TICAM1 |
| trigeminal ganglion development | biological process | SEMA3A, NRP2, SIX1, SIX4, NRP1 |
| trigeminal nerve development | biological process | ISL1, NEUROG1, TFAP2A, TIFAB, POU4F1 |
| trigeminal nerve morphogenesis | biological process | PLXNA4, NRP1 |
| trigeminal nerve structural organization | biological process | SEMA3A, SEMA3F, PLXNA4, NRP1, PLXNA3 |
| triglyceride acyl-chain remodeling | biological process | PNPLA3 |
| triglyceride biosynthetic process | biological process | MOGAT1, GK, LPL, AGMO, ACSL1, DGAT2, LPIN1, DGAT1, PNPLA3, ACSL4, GPAM, LPIN2, GPAT3, MOGAT2, MOGAT3, LPIN3 |
| triglyceride catabolic process | biological process | APOE, APOB, LIPE, LPL, CPS1, FABP5, FABP3, FABP6, LIPC, DDHD2, PNPLA3, PNPLA4, APOA5, FABP7, APOC3, MGLL, PNPLA1, PNPLA5 |
| triglyceride homeostasis | biological process | NR1H3, PNPLA8, ANGPTL8, LPL, SCARB1, GPIHBP1, LIPC, RORA, MED13, ANGPTL3, ACSM2A, APOA1, NR1H4, APOA5, ANGPTL4, HNF4A, SESN2, CETP, APOC3, PLA2G12B |
| triglyceride metabolic process | biological process | APOE, GPX1, CAT, PTPN11, GK2, LIPF, GK, LPL, PLAAT3, CPT1A, NKX2-3, CAV3, DGAT1, GK5, SEL1L, APOC1, GPAM, INSIG1, APOA5, SLC22A4, CYP2E1, CETP, PNLIPRP2, PCSK9, APOC3, LMF1, APOBEC1, APOH, CAV1, APOBR, INSIG2 |
| triglyceride mobilization | biological process | APOB, SLC27A5, LPIN1 |
| triglyceride transport | biological process | VAMP7, CETP, MTTP, APOH, CD36 |
| triglyceride-rich lipoprotein particle remodeling | biological process | APOA5 |
| trimming of first mannose on A branch | biological process | EDEM2 |
| trimming of second mannose on A branch | biological process | EDEM2 |
| trimming of terminal mannose on B branch | biological process | MAN1B1, EDEM2 |
| trimming of terminal mannose on C branch | biological process | EDEM2, EDEM1 |
| tripeptide import across plasma membrane | biological process | SLC15A1 |
| triterpenoid biosynthetic process | biological process | LSS |
| tRNA (guanine-N7)-methylation | biological process | WDR4 |
| tRNA 3'-end processing | biological process | TRNT1, PTCD1, SSB, ELAC2 |
| tRNA 3'-terminal CCA addition | biological process | TRNT1 |
| tRNA 3'-trailer cleavage | biological process | ELAC1, POLR3K |
| tRNA 3'-trailer cleavage, endonucleolytic | biological process | ELAC1 |
| tRNA 5'-leader removal | biological process | POP4, RPP14, RPP38, SSB, POP1, RPP25, RPP25L, PRORP, POP5, RPP21, POP7 |
| tRNA acetylation | biological process | NAT10 |
| tRNA aminoacylation | biological process | FARS2, EPRS1, DARS2, TARS1, AARS1, AARS2, AARSD1, TARS2, QARS1, FARSA, TARS3, EARS2 |
| tRNA aminoacylation for mitochondrial protein translation | biological process | EARS2 |
| tRNA aminoacylation for protein translation | biological process | FARS2, KARS1, NARS1, MARS1, EPRS1, IARS1, AIMP2, EEF1E1, YARS1, PPA2, HARS1, CARS1, RARS1, DARS2, SARS2, IARS2, WARS1, HARS2, TARS1, CARS2, AARS1, DALRD3, LARS1, SARS1, GARS1, PARS2, AIMP1, PPA1, RARS2, FARSB, NARS2, TARS2, VARS1, QARS1, LARS2, FARSA, TARS3, EARS2, VARS2 |
| tRNA C5-cytosine methylation | biological process | NSUN6 |
| tRNA catabolic process | biological process | POP1, SLFN11 |
| tRNA demethylation | biological process | ALKBH1 |
| tRNA dihydrouridine synthesis | biological process | DUS1L, DUS2, DUS3L |
| tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate | biological process | RTCB |
| tRNA export from nucleus | biological process | NUP93, NUP37, NUP88, NUP85, NUP107, NUP43, POM121, NUP35, NUP58, SSB, SEC13, NUP205, NUP50, NUP62, NUP155, NUP153, RAE1, SEH1L, XPOT, RAN, NUP133, NUP54, TPR, RANBP2, NUP98, AAAS, NUP210, NUP188, NUP42, NUP214, NUP160, NOL6 |
| tRNA import into mitochondrion | biological process | TOMM20, TOMM20L |
| tRNA metabolic process | biological process | DTD2, DTD1 |
| tRNA methylation | biological process | METTL2A, NSUN2, METTL2B, NSUN6, TRMT5, TYW3, THADA, TRMT61A, TRMT13, WDR4, TRMT12, FTSJ1, TRMT44, METTL6, GTPBP3, THUMPD2, TRMT9B, MTO1, THUMPD3, TRMT61B, TRMT6, TRDMT1, TRMT10A, ALKBH8, LCMT2 |
| tRNA methylthiolation | biological process | CDK5RAP1, CDKAL1 |
| tRNA modification | biological process | THG1L, QTRT2, NSUN2, CDK5RAP1, SSB, NSUN6, C9orf64, TRUB1, TRMT61A, AARS1, WDR4, AARS2, TRIT1, FTSJ1, GTPBP3, TRMT9B, DTWD1, PUS3, THUMPD1, TRMT6, ANKRD16, TRDMT1, URM1, TYW5, CTU1, LCMT2, TRMT1, ADAT3, CTU2, CDKAL1, QTRT1 |
| tRNA N1-guanine methylation | biological process | TRMT5 |
| tRNA N2-guanine methylation | biological process | TRMT1L, TRMT1 |
| tRNA nucleoside ribose methylation | biological process | FTSJ1 |
| tRNA processing | biological process | THG1L, ADAT1, FARS2, POP4, DDX1, RPP14, KARS1, METTL2A, QTRT2, NSUN2, GRSF1, ELP2, METTL2B, TRNT1, CDK5RAP1, RPP38, RPUSD4, PTCD1, SSB, RTCB, MOCS3, ZBTB8OS, ELP4, TPRKB, TRMT5, TYW3, POP1, ELAC1, TRMT61A, ELAC2, TRMT13, AARS1, WDR4, TRMT12, PUSL1, RPP25, PUS10, TRMT10C, TRIT1, ELP5, FTSJ1, PRORP, LAGE3, TRMT44, METTL6, GTPBP3, TRMT9B, DUS1L, MTO1, ELP1, SARS1, DTWD1, PUS3, DUS2, TRPT1, TRMT61B, TRMT6, TRMT1L, LSM6, TRDMT1, TRMU, POP5, HSD17B10, URM1, OSGEP, ELP3, TYW5, CTU1, TSEN15, RPP21, LCMT2, TSEN2, TP53RK, TRMT1, POP7, ADAT3, CTU2, CDKAL1, DUS3L, QTRT1, ELP6, TYW1B, PUS7, NAT10, TYW1, CLP1 |
| tRNA pseudouridine synthesis | biological process | PUSL1, PUS10, PUS3, PUS7 |
| tRNA re-export from nucleus | biological process | XPOT |
| tRNA splicing, via endonucleolytic cleavage and ligation | biological process | CSTF2, DDX1, RTRAF, CPSF4, RTCB, ZBTB8OS, FAM98B, TRPT1, CPSF1, TSEN15, C2orf49, TSEN2, CLP1 |
| tRNA stabilization | biological process | NSUN2, TRDMT1 |
| tRNA thio-modification | biological process | MOCS3, URM1, CTU1, CTU2 |
| tRNA threonylcarbamoyladenosine metabolic process | biological process | LAGE3, CTAG2, CTAG1A, TP53RK |
| tRNA threonylcarbamoyladenosine modification | biological process | TPRKB, OSGEP |
| tRNA transcription | biological process | GTF3C1, BRF1 |
| tRNA transcription by RNA polymerase III | biological process | GTF3C6, GTF3C3, POLR2L, GTF3C1, GTF3C2, GTF3C5, GTF3C4 |
| tRNA transport | biological process | YBX1 |
| tRNA wobble adenosine to inosine editing | biological process | ADAT3 |
| tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation | biological process | ELP1, ELP3 |
| tRNA wobble base cytosine methylation | biological process | NSUN3 |
| tRNA wobble cytosine modification | biological process | ALKBH1 |
| tRNA wobble position uridine thiolation | biological process | MOCS3, TRMU, URM1, CTU1, CTU2 |
| tRNA wobble uridine modification | biological process | ELP2, MOCS3, ELP4, ELP5, GTPBP3, TRMT9B, MTO1, ELP1, DPH3, URM1, CTU1, ALKBH8, CTU2, ELP6 |
| tRNA-guanine transglycosylation | biological process | QTRT2, C9orf64, QTRT1 |
| tRNA-type intron splice site recognition and cleavage | biological process | TSEN2 |
| trochlear nerve development | biological process | HES1 |
| trochlear nerve formation | biological process | PHOX2A |
| trophectodermal cell differentiation | biological process | NODAL, EOMES, RBM46, SP3, CTR9, HOPX, JUNB, CNOT2, ADA, SRF, CDX2, CNOT3 |
| trophectodermal cell proliferation | biological process | ACVR1C, ZPR1 |
| trophectodermal cellular morphogenesis | biological process | NODAL |
| trophoblast giant cell differentiation | biological process | LIF, NR2F2, SENP2, PRDM1, GJB5, SOX15, E2F7, E2F8, PLG, MDFI, SOCS3 |
| tryptophan catabolic process | biological process | HAAO, KYNU, IDO2, IDO1, KYAT1, AADAT, AFMID |
| tryptophan catabolic process to acetyl-CoA | biological process | KYNU |
| tryptophan catabolic process to kynurenine | biological process | KYNU, IDO2, IDO1, AFMID |
| tryptophan metabolic process | biological process | GCDH, ATP7A |
| tryptophan transport | biological process | ACE2, SLC36A4, SLC3A2 |
| tryptophanyl-tRNA aminoacylation | biological process | WARS1 |
| tube development | biological process | GLI3, ITGB3, GLI2 |
| tube formation | biological process | VEGFA, BCL2L11, DAB2IP, NOTCH1, YWHAZ, SDCCAG8, ITGB1BP1, BCAS3 |
| tube morphogenesis | biological process | BMP7, LGR4, FOXA1, WNT4, PDPN, GBX2 |
| tubulin complex assembly | biological process | CRYAB, TCP1, VBP1, ARL2, TBCC, TBCA, TBCE, TBCD |
| tubulin deacetylation | biological process | SIRT2, HDAC6 |
| tumor necrosis factor production | biological process | TLR9, WDR83 |
| tumor necrosis factor secretion | biological process | SPHK2, HMGB1, TMEM106A |
| tumor necrosis factor-mediated signaling pathway | biological process | TNF, TNFRSF1A, TNFRSF1B, FAS, STAT1, PSMA3, TNFRSF25, PSMB1, PSMB5, PSMC2, PSMA8, PSMA7, JAK2, TNFSF15, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, KARS1, PSMB7, PSMD6, PSMD1, TNFRSF11B, PSMD14, PSMD7, PSMB6, TNFSF12, PSMD10, PSMD8, PSMC5, EDARADD, BAG4, PSMB4, PSME1, LTB, TRAF3, PSMB8, PSMD4, PSMC3, PSMA6, TNFRSF17, TNFRSF19, KRT18, RELA, TNFRSF9, TNFRSF6B, NFKBIA, TNFRSF4, PYDC1, TNFRSF8, BIRC2, TNFSF13B, PSMD12, PSMB9, PSMC4, PSMD9, AIM2, PSMA4, PSMD2, TRAF6, PSMD5, PSMF1, TRAF4, CDIP1, TNFSF4, PSMB3, TNFRSF14, TNFRSF12A, TNFRSF18, IKBKB, ILK, TRADD, MAP3K14, TRAF5, PSMD3, TNFSF14, PSMC1, EDA, TNFRSF13C, TXNDC17, PYCARD, TNFRSF11A, KRT8, EDAR, TNFSF8, FOXO3, TNFSF9, TRAF1, EDA2R, TNFRSF13B, LTBR, ACTN4, CD40, TRAF2, PLVAP, CARD14, ST18, PTK2B, TNFSF13, LTA, PSMD13, TP53, PSMB10 |
| type 2 immune response | biological process | IL4, IL10, IL18, IL33, BCL6, STARD7, BCL6B |
| type B pancreatic cell apoptotic process | biological process | RYR2, CAPN10 |
| type B pancreatic cell development | biological process | BMP4, NKX2-2, SMO, BMP5, CDK6, INSM1, SIDT2, BMP6, HNF4A, DLL1, PDPK1 |
| type B pancreatic cell differentiation | biological process | PDX1, MEN1, INSM1, RFX6 |
| type B pancreatic cell fate commitment | biological process | NKX2-2 |
| type B pancreatic cell maturation | biological process | RFX3 |
| type B pancreatic cell proliferation | biological process | BAD, ANGPTL8, BTBD10, SERPINB1, IGFBP4, SIDT2, CCN3, IGFBP5 |
| type I interferon biosynthetic process | biological process | IRF7, IRF3 |
| type I interferon production | biological process | TBK1, G3BP1 |
| type I interferon signaling pathway | biological process | IFNA1, HLA-B, HLA-A, HLA-E, TYK2, STAT1, IFNAR2, HLA-G, HLA-C, OAS1, BST2, IRAK1, ADAR, ISG20, MYD88, EGR1, IFNA8, PSMB8, IFI6, IRF9, OASL, XAF1, RSAD2, IFIT1, RNASEL, MX1, IFI35, IRF6, IFNA10, ISG15, IFNAR1, GBP2, IRF5, JAK1, SP100, IFITM3, SAMHD1, IFITM1, IFI27, IFITM2, IFIT2, IRF2, STAT2, IRF1, IRF8, IRF7, MX2, IFNA2, IFNA14, IP6K2, IRF3, TREX1, OAS2, HLA-F, IFIT3 |
| Type I pneumocyte differentiation | biological process | THRB, NFIB, KLF2, THRA |
| type II pneumocyte differentiation | biological process | AIMP2, NFIB, FGF10, NKX2-1 |
| type IV hypersensitivity | biological process | GATA3 |
| tyrosine biosynthetic process | biological process | PAH |
| tyrosine catabolic process | biological process | FAH, HGD, GSTZ1, TAT, HPD |
| tyrosine metabolic process | biological process | HGD, IYD, THAP4 |
| tyrosine phosphorylation of STAT protein | biological process | LEP, F2R, JAK2, IL15, FER, JAK3, PTK6, IFNL4 |
| tyrosine phosphorylation of Stat3 protein | biological process | LIF, IL21 |
| tyrosine transport | biological process | OCA2 |
| tyrosyl-tRNA aminoacylation | biological process | YARS1 |
| U1 snRNA 3'-end processing | biological process | EXOSC9, EXOSC7, EXOSC8 |
| U2 snRNA 3'-end processing | biological process | INTS1 |
| U2-type prespliceosome assembly | biological process | SF3A1, SF3A3, SF3A2 |
| U4 snRNA 3'-end processing | biological process | EXOSC9, EXOSC7, EXOSC5, EXOSC3, EXOSC8, EXOSC4, EXOSC6, EXOSC2 |
| U5 snRNA 3'-end processing | biological process | EXOSC9, EXOSC7, EXOSC8 |
| U6 snRNA 3'-end processing | biological process | TUT1, USB1 |
| ubiquinone biosynthetic process | biological process | COQ8A, COQ10B, COQ9, COQ8B, COQ3, UBIAD1, PDSS2, COQ5, PDSS1, COQ7, COQ6 |
| ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate | biological process | UBIAD1 |
| ubiquinone metabolic process | biological process | HMGCR |
| ubiquinone-6 biosynthetic process | biological process | NDUFA9 |
| ubiquitin recycling | biological process | FBXW7, IDE, PLAA |
| ubiquitin-dependent endocytosis | biological process | IL10RA, LRSAM1, NEURL1B, NEURL3 |
| ubiquitin-dependent glycoprotein ERAD pathway | biological process | EDEM2, EDEM1 |
| ubiquitin-dependent protein catabolic process | biological process | USP9Y, USP1, UBE2B, UBR2, USP26, BAG6, RNF8, PSMA3, USP8, PSMC2, TTC3, UBE2D3, UBE3A, ELOC, RNF20, SIAH1, USP38, PSMA8, RNF34, FEM1C, USP47, HECW2, NUB1, PSMA7, PSMA1, PSMA2, PSMA5, PSMC6, UBE4A, KEAP1, TRIP12, UBE3C, FBXO11, CACUL1, MIB1, USP13, ITCH, KLHL8, BUB3, CNOT4, USP14, SKP1, CDC16, CUL9, RNF168, RNF149, NTAN1, KLHL25, RNF19A, CDC23, FBXL5, USP16, USP3, PSMD14, SIAH2, ANAPC15, TRIM25, UBE3B, HUWE1, DTX3L, TRPC4AP, FBXO8, FBXL12, RNF14, FZR1, BTRC, ARIH1, XBP1, UBE2G1, RNF144B, FBXL13, USP32, TRIM58, ANAPC16, BUB1B, ARIH2, RBBP6, CHFR, USP28, USP29, DTL, ANAPC5, FBXO2, PRKN, UBE2H, CUL1, RNF217, RNF167, ANKIB1, UBD, SPSB3, USP30, USP51, MAEA, USP37, RMND5A, FBXO4, STUB1, PSMA6, UFD1, FBXO10, FBXL4, USP22, RNF6, UBE2D4, WDR91, UBE2I, TRIM32, HERPUD1, NEDD8, UBR4, RNF43, USP31, LNX1, UBE2Z, ANAPC7, NEDD4, UBR1, RNF150, ATXN3, SQSTM1, WDR81, FBXL16, USP33, CUL5, PINK1, USP2, PLK1, MAD2L1, ADRM1, RNF213, UBR3, USP45, UBQLNL, ZNRF4, USP44, UBQLN3, RLIM, DMAC2, USP27X, SPOP, TAF1, UBE2L3, SKP2, SIAH3, MYLIP |
| ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway | biological process | TSG101, VPS28, VPS4B, PTPN23, UBAP1, NEDD4, VPS37C, TOM1L1, RNF126, VPS37A, VPS37B, HDAC6, MVB12A, PLAA, MVB12B, RNF115 |
| ubiquitin-dependent protein catabolic process via the N-end rule pathway | biological process | UBR2, UBR1, UBR3 |
| ubiquitin-dependent SMAD protein catabolic process | biological process | STUB1, TGFB1I1, RNF111, SMURF2 |
| ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway | biological process | VPS4B, CHMP4B, PDCD6IP, CHMP4C |
| UDP biosynthetic process | biological process | CMPK1 |
| UDP catabolic process | biological process | ENTPD4 |
| UDP phosphorylation | biological process | AK9 |
| UDP-D-xylose biosynthetic process | biological process | UXS1 |
| UDP-galactose transmembrane transport | biological process | SLC35A1, SLC35B1, SLC35A3, SLC35A2 |
| UDP-glucose catabolic process | biological process | GALT |
| UDP-glucose metabolic process | biological process | GALT, UGP2 |
| UDP-glucose transmembrane transport | biological process | SLC35B1 |
| UDP-glucosylation | biological process | UGGT1, UGGT2 |
| UDP-glucuronate biosynthetic process | biological process | UGP2, SLC35D1, UGDH |
| UDP-glucuronate metabolic process | biological process | CSGALNACT1 |
| UDP-glucuronic acid transmembrane transport | biological process | SLC35D1, SLC35D2 |
| UDP-N-acetylgalactosamine metabolic process | biological process | CSGALNACT1, EXTL2, B4GALNT2 |
| UDP-N-acetylgalactosamine transmembrane transport | biological process | SLC35D1, SLC35D2 |
| UDP-N-acetylglucosamine biosynthetic process | biological process | UAP1, PGM3, GFPT1, GNPDA1, NAGK, GNPDA2, GNPNAT1, RENBP, AMDHD2 |
| UDP-N-acetylglucosamine metabolic process | biological process | UAP1, GFPT1, DPAGT1, SLC35A3, GNE, B4GALNT2 |
| UDP-N-acetylglucosamine transmembrane transport | biological process | SLC35D1, SLC35D2, SLC35A3 |
| ultradian rhythm | biological process | ENOX1 |
| umbilical cord morphogenesis | biological process | HEY2, HEY1 |
| UMP biosynthetic process | biological process | UPRT, CMPK1, UMPS |
| UMP salvage | biological process | UCK1, UPP1, UCKL1, UCK2, UPP2 |
| uncoating of virus | biological process | PPIA |
| unidimensional cell growth | biological process | EPB41L5, BIN3 |
| unsaturated fatty acid biosynthetic process | biological process | SCD, ELOVL6, ELOVL4, ELOVL2, ELOVL5, DEGS1, SCD5, FADS3, FADS1, ELOVL1, ELOVL3, DECR2, FADS2 |
| unsaturated monocarboxylic acid metabolic process | biological process | ACOT4 |
| uracil catabolic process | biological process | DPYS, DPYD |
| uracil metabolic process | biological process | TYMS, DPYS |
| urate biosynthetic process | biological process | PNP, PRPS1 |
| urate catabolic process | biological process | URAD |
| urate homeostasis | biological process | OIT3 |
| urate metabolic process | biological process | SLC17A3, SLC22A12, SLC17A1, CARMIL1, SLC16A9, SLC22A11, ABCG2 |
| urate salt excretion | biological process | ABCG2 |
| urate transport | biological process | SLC17A3, SLC22A12, SLC17A1, SLC22A13, ABCG2 |
| urea cycle | biological process | ARG2, CPS1, ASS1, FH, SLC25A15, SLC25A2, ASL, NMRAL1 |
| urea homeostasis | biological process | SLC25A23 |
| urea metabolic process | biological process | CYP2C9 |
| urea transmembrane transport | biological process | AQP7, SLC14A1, AQP9, AQP3, AQP10, SLC14A2 |
| urea transport | biological process | SLC14A1, AQP11, AQP3, UPK3A, SLC14A2 |
| ureter development | biological process | SOX9, NFIA, NPHP3, FOXF1 |
| ureter epithelial cell differentiation | biological process | BMP4 |
| ureter maturation | biological process | ALDH1A2, GATA3, RET |
| ureter morphogenesis | biological process | SOX9, GATA3, LHX1, EMX2, LZTS2 |
| ureter smooth muscle cell differentiation | biological process | SOX9, BMP4, SIX1 |
| ureter urothelium development | biological process | SOX9 |
| ureteric bud development | biological process | TGFB1, BCL2, WT1, FGFR2, FGFR1, BMP7, CAT, BMP4, ARG2, GDNF, RARB, EPCAM, CER1, SPRY1, SDC4, ROBO2, GDF11, SIM1, LHX1, SMAD6, DLG1, FOXC2, SMAD2, CRLF1, SIX1, RET, EYA1, SALL1, FOXC1, BMPER, SLIT2, SDC1, SMAD3, SMAD5, RARA |
| ureteric bud elongation | biological process | HNF1B |
| ureteric bud formation | biological process | GDNF, GATA3, GREM1 |
| ureteric bud invasion | biological process | KIF26B, SALL1, FMN1 |
| ureteric bud morphogenesis | biological process | HES1, TACSTD2, WNT11 |
| uridine catabolic process | biological process | UPP1, UPP2 |
| uridine metabolic process | biological process | UPP1, UPP2 |
| uridine transport | biological process | SLC28A2, SLC28A1, SLC29A2, SLC29A1, SLC28A3 |
| urinary bladder development | biological process | TP63, MYOCD, RBP4, UPK3A |
| urinary bladder smooth muscle contraction | biological process | PLA2G6, P2RX3, P2RX2, TRPV1 |
| urogenital system development | biological process | AMH, SRD5A1, NKX3-1, EPHB2, PAX8, LHX1, PBX1, GATA2, FOXB1, EPHB3, CRKL, OSR2 |
| urokinase plasminogen activator signaling pathway | biological process | PLAUR |
| uropod organization | biological process | CORO1A, MYH9 |
| uroporphyrinogen III biosynthetic process | biological process | UROS |
| urothelial cell proliferation | biological process | FGF10 |
| uterine epithelium development | biological process | LHX1 |
| uterine gland development | biological process | ASH1L |
| uterine smooth muscle contraction | biological process | AGT |
| uterine wall breakdown | biological process | TGFB3, TGFB2 |
| uterus development | biological process | ESR1, SRC, SMAD4, GATA3, LHX1, TGFB2, GREB1L, MYOCD, HOXA11, RBP4, HOXA9, FOXL2, WNT7A, HOXA10 |
| uterus morphogenesis | biological process | KDM5B, WNT9B, NIPBL, ASH1L, STRA6, WNT7A |
| UTP biosynthetic process | biological process | NME8, NME7, NME5, NME9, NME6, NME2, NME3, NME1, NME4, CAD |
| UTP metabolic process | biological process | AK3 |
| UV protection | biological process | ERCC1, ERCC2, GPX1, CAT, FEN1, MFAP4, ERCC5, ERCC4, SCARA3, MC1R |
| UV-damage excision repair | biological process | XPA, XPC, DDB2, INO80, MC1R, DDB1, ACTR5 |
| V(D)J recombination | biological process | RAG1, LIG4, ATM, DCLRE1C, DCAF1, HMGB1, PRKDC, LIG1, LIG3, RAG2 |
| vacuolar acidification | biological process | ATP6V0A2, CLIC4, ATP6V0E1, DMXL1, DMXL2, ATP6V0E2, ATP6V1H, SLC11A1, ATP6V0D1, ROGDI, ATP6V0A4, TCIRG1, ATP6V0A1 |
| vacuolar protein processing | biological process | TMEM208, LGMN |
| vacuolar proton-transporting V-type ATPase complex assembly | biological process | ATP6V0A2, VMA21, TMEM199, ALDOB, TM9SF4, CCDC115 |
| vacuolar sequestering | biological process | GAA |
| vacuolar transport | biological process | CHMP2A, CHMP5, CHMP4A, CHMP4B, CHMP1A, CHMP6, NDFIP1, NDFIP2, ATP6V0D1, CHMP4C, CHMP7, CHMP3, CHMP1B |
| vacuole fusion, non-autophagic | biological process | VPS41 |
| vacuole organization | biological process | NDP, VPS18, MAN2A1, VPS4B, VPS16 |
| vagina development | biological process | ESR1, BAX, BAK1, AXL, LHX1, LRP2, RBP4, MERTK, TYRO3 |
| vagus nerve development | biological process | NAV2 |
| vagus nerve morphogenesis | biological process | PLXNA4 |
| valine biosynthetic process | biological process | BCAT1, BCAT2 |
| valine catabolic process | biological process | HIBADH, HIBCH, ALDH6A1, ACAD8 |
| valine metabolic process | biological process | ALDH6A1, BCAT2 |
| valyl-tRNA aminoacylation | biological process | VARS1, VARS2 |
| vascular endothelial cell response to fluid shear stress | biological process | SOCS5 |
| vascular endothelial growth factor production | biological process | HIF1A, ADAMTS3, TNF |
| vascular endothelial growth factor receptor signaling pathway | biological process | VEGFA, HSP90AA1, FLT1, AXL, KDR, HSPB1, PGF, ITGAV, SRC, PIK3CA, BMPR2, ACTB, CDC42, MAPK14, BAIAP2, NCKAP1, PIK3R1, PXN, MAPK11, CYBB, NCK1, XBP1, VAV3, PTK2, PRKD1, ROCK2, FLT4, NCK2, BCAR1, SH2D2A, CYBA, ROCK1, CYFIP2, NRP2, ITGB3, NCF1, RAC1, ELMO2, WASF2, VAV2, CYFIP1, ABI1, FOXC2, VEGFC, DOCK1, MAPKAPK3, NCKAP1L, NCF4, PRKD2, VEGFB, SULF1, CRK, FOXC1, PIK3R2, NRP1, VAV1, SHC2, PTK2B, SHB, ELMO1 |
| vascular endothelial growth factor receptor-1 signaling pathway | biological process | FLT1 |
| vascular endothelial growth factor receptor-2 signaling pathway | biological process | CLEC14A, DAB2IP, PDCD6 |
| vascular endothelial growth factor receptor-3 signaling pathway | biological process | CLEC14A |
| vascular endothelial growth factor signaling pathway | biological process | VEGFA, FLT1, FLT4, NUS1, NRP2, GAB1, VEGFC, VEGFB, FOXC1, NRP1 |
| vascular smooth muscle cell development | biological process | ADM, HES1, RAMP2, SGCB, HEY2, ENG, COMP |
| vascular smooth muscle cell differentiation | biological process | EPC1, MYOCD |
| vascular smooth muscle contraction | biological process | PIK3C2A, RAP1GDS1, SLC8A1, COMP, ACTA2 |
| vascular transport | biological process | GJA1 |
| vascular wound healing | biological process | HPSE, CD34, ADIPOR2, GATA2, NDNF, MCAM |
| vasculature development | biological process | HIF1A, NODAL, CTNNB1, BMP4, PIK3CA, SHH, SPI1, ZFAND5, ANP32B, FBXW7, SOX18, B9D1, FLT4, LEF1, NOTCH4, LRP5, CALCA, CDH5, FZD5, CCM2, RIC8A, IHH |
| vasculogenesis | biological process | VEGFA, WT1, ADM, KDR, CTNNB1, SHH, RASA1, ZFPM2, FBXW7, FZD4, AGGF1, TIE1, SOX18, PTK2, ZMIZ1, RAMP2, AMOT, CITED1, NTRK2, TIPARP, HAS2, ACKR3, SMO, TEAD2, HDAC7, JUNB, QKI, ITGB8, YAP1, ZFP36L1, MYOCD, TMEM100, HEY2, TBX20, CUL7, EPHA2, TGFBR2, EGFL7, APLNR, FOXF1, MYO18B, CCM2, ENG, TBX6, NKX2-5, GDF2, RASIP1, PAXIP1, GJC1, CAV1 |
| vasculogenesis involved in coronary vascular morphogenesis | biological process | SPRED1, NOTCH1 |
| vasoconstriction | biological process | EDNRA, BDKRB2, HTR7, EDNRB, SLC6A4, AVP, KEL, HTR1B, EDN1, TRPM4, AGT, EDN3, HTR2B, CAV1 |
| vasodilation | biological process | APOE, GPX1, BBS2, BDKRB2, CPS1, MKKS, ATG5, EDNRB, GCH1, CALCA, PLOD3, DRD1, ADORA2A, AGT |
| vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure | biological process | SOD2 |
| vasomotion | biological process | GJA5 |
| vasopressin secretion | biological process | NPFF, ECRG4 |
| VEGF-activated neuropilin signaling pathway | biological process | VEGFA, NRP1 |
| VEGF-activated neuropilin signaling pathway involved in axon guidance | biological process | NRP1 |
| vein smooth muscle contraction | biological process | EDNRB, EDN1, EDN3 |
| venous blood vessel development | biological process | BMPR2, ACVR2B, FOXF1, ACVRL1 |
| venous blood vessel morphogenesis | biological process | CCBE1, NOTCH1, EFNB2, CCM2, ENG, PROX1 |
| venous endothelial cell differentiation | biological process | NOTCH1 |
| ventral midline determination | biological process | SMO |
| ventral midline development | biological process | SHH, GLI1, GLI2 |
| ventral spinal cord development | biological process | VLDLR, LHX1, GLI2, RELN |
| ventral spinal cord interneuron differentiation | biological process | GATA2 |
| ventral spinal cord interneuron fate commitment | biological process | ASCL1, FOXN4 |
| ventral spinal cord interneuron fate determination | biological process | NKX2-2 |
| ventral spinal cord interneuron specification | biological process | LHX3, DMRT3 |
| ventral trunk neural crest cell migration | biological process | SEMA3A, SEMA3F, NRP2, NRP1 |
| ventricular cardiac muscle cell action potential | biological process | KCNH2, RYR2, CAV3, ANK2, GPD1L, NEDD4L, KCNE4, PKP2, GJA5, KCNE1, SNTA1, SCN5A, SCN3B, KCNE3 |
| ventricular cardiac muscle cell development | biological process | CDK1, CCNB1, MYH10, ATG5, FHL2, HEY2, NKX2-5 |
| ventricular cardiac muscle cell differentiation | biological process | NRG1, RARB, MEF2C, MYOCD, RARA |
| ventricular cardiac muscle cell membrane repolarization | biological process | KCND3 |
| ventricular cardiac muscle tissue development | biological process | ZMPSTE24, ADAMTS9, TBX5, PPP1R13L |
| ventricular cardiac muscle tissue morphogenesis | biological process | MYH7, FGFR2, TGFBR3, TPM1, COL11A1, ISL1, MYBPC3, FOXC2, PKP2, MYL2, FOXC1, PROX1, MYL3, MYH6, TNNI1 |
| ventricular cardiac myofibril assembly | biological process | MEF2A, NKX2-5, PROX1 |
| ventricular compact myocardium morphogenesis | biological process | BMPR1A, DSP, LRP2, TGFBR1, POU4F1 |
| ventricular septum development | biological process | MDM2, GATA4, CCN1, MATR3, LTBP1, PTK7, CPLANE1, HES1, MDM4, DCTN5, PRDM1, GATA3, PAX8, SALL4, SMAD6, LRP2, TRIP11, TBX5, AP2B1, SUFU, XIRP2, FRS2, WNT11, GJA5, NPRL3, DAND5, SALL1, PDE2A, LUZP1, STRA6, HECTD1 |
| ventricular septum morphogenesis | biological process | ZFPM2, RBM15, SMAD4, ACVR1, HES1, FZD2, NOTCH1, ROBO2, SOX11, TGFB2, SAV1, RBPJ, TGFBR1, SOX4, CITED2, EGLN1, HEY2, TBX3, WNT11, GJA5, TGFBR2, HEY1, NKX2-5, PROX1, FZD1, SLIT3, SLIT2, ZFPM1, ROBO1 |
| ventricular system development | biological process | ARMC4, SEMA6D, NME5, DPCD, ANP32B, RAPGEF2, CORO1C, BBS4, CENPF, HYDIN, TTC21B, CELSR2, MECP2, WDR89, KIF27, AK8, MNAT1, MBOAT7, CCDC134 |
| ventricular trabecula myocardium morphogenesis | biological process | NRG1, BMPR1A, NOTCH1, TGFB2, RBPJ, TGFBR1, HEY2, UBE4B, ENG, NKX2-5, FOXH1 |
| ventricular zone neuroblast division | biological process | FGFR2, FGFR1, DCT |
| vertebrate eye-specific patterning | biological process | ITGAM, C1QA |
| very long-chain fatty acid biosynthetic process | biological process | HACD1, ELOVL6, ELOVL4, HACD2, ELOVL2, ELOVL5, HACD3, TECRL, TECR, ELOVL1, ELOVL3 |
| very long-chain fatty acid catabolic process | biological process | ABCD2, SLC27A2, SLC27A4, ABCD1 |
| very long-chain fatty acid metabolic process | biological process | HSD17B4, PEX2, ACSL1, ACAA1, SLC27A5, ABCD2, ELOVL2, SLC27A2, CYP4F12, ACOT2, CYP4F2, SLC27A4, ABCD1, ACSBG1, ACOX1, ACOT4 |
| very long-chain fatty-acyl-CoA catabolic process | biological process | ABCD1 |
| very long-chain fatty-acyl-CoA metabolic process | biological process | HSD17B4 |
| very-low-density lipoprotein particle assembly | biological process | APOB, P4HB, ACSL3, ARF1, DGAT1, SOAT1, MFSD2A, APOC1, LPCAT3, APOC3, MTTP |
| very-low-density lipoprotein particle clearance | biological process | APOE, VLDLR, APOC1, APOBR |
| very-low-density lipoprotein particle remodeling | biological process | APOE, LPL, LIPC, APOA1, APOA5, CETP, LCAT |
| vesicle cargo loading | biological process | PICALM, TMED2, CTAGE8, CTAGE4, TMED10, MIA3, CTAGE1, KIF13A |
| vesicle cytoskeletal trafficking | biological process | F8A1, CCDC186 |
| vesicle docking | biological process | STX12, STX8, STX10, STX5, BVES, STX3, NDRG4, SYT1, STX17, STX7, CAV2, STX1B, STX16, TSNARE1, STX4, STX11, CEP83 |
| vesicle docking involved in exocytosis | biological process | CFTR, SCFD2, RABEPK, VPS18, EXOC6B, SCFD1, VTI1B, RAB3C, PLEK, VPS33B, RAB8B, VPS45, RAB15, EXOC6, RAB3B, STX1B, KCNB1, VAMP3, SYTL2, EXOC4, STXBP3, RAB8A, YKT6, RAB3D, VPS33A, STXBP2, CPLX2 |
| vesicle fusion | biological process | STX12, SNAP23, GOSR1, SYT13, STX8, STX10, STX5, C2CD5, VAV3, STX3, VAMP8, GNAI3, VAMP1, SNAP29, STX17, STX7, CAV2, STX1B, SNAP25, VAMP3, STX16, VAMP7, EEA1, SNAP47, TSNARE1, STX4, STX11, DYSF, IRAG2 |
| vesicle fusion to plasma membrane | biological process | TRARG1 |
| vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane | biological process | SEC22B, TAP1, TAP2, TAPBP, STX4, CALR |
| vesicle fusion with Golgi apparatus | biological process | USO1, SEC22B, STX5, VTI1B, BET1, VAMP7, GOSR2, VTI1A |
| vesicle localization | biological process | TPGS1 |
| vesicle organization | biological process | WASL, SAR1A, ALS2, FNBP1L, EPS15, ZFYVE16, SAR1B, CAV2, SORT1, CD2AP, PLEKHF1, CAV1 |
| vesicle scission | biological process | SH3GL2 |
| vesicle targeting | biological process | MAP4K2, SNAP23, SNAP29, CLASP2, YKT6, IRAG2, CLASP1 |
| vesicle targeting, to, from or within Golgi | biological process | TMED10 |
| vesicle targeting, trans-Golgi to endosome | biological process | AP1AR, WIPI1 |
| vesicle targeting, trans-Golgi to periciliary membrane compartment | biological process | CEP19 |
| vesicle tethering involved in exocytosis | biological process | EXOC4 |
| vesicle tethering to endoplasmic reticulum | biological process | STARD3NL, STARD3 |
| vesicle tethering to Golgi | biological process | TBC1D23, TRIP11, FAM91A1, C17orf75 |
| vesicle transport along actin filament | biological process | WASL, MYO5C, FNBP1L, MYO5A, MYO6, MYO1B, MYO5B, MYO1F, MYO1C, MYO7A, MYO7B, MYO1G, ACTN4, MYO1D |
| vesicle transport along microtubule | biological process | KIF5B, TRAK2, RAB1A, DYNC1I1, RASGRP1, TRAK1, VAMP7, PRKCZ, CLN3, HTT, BICDL1, NDE1, HAP1 |
| vesicle-mediated cholesterol transport | biological process | SYT7 |
| vesicle-mediated transport | biological process | USO1, HSPA8, ARF4, ARCN1, VPS41, STX12, OPTN, KIF17, RAB11A, MLC1, RABEP1, SEC23B, SCFD2, RAB2B, SFT2D1, SEC22C, OSBPL1A, SAR1A, AP3M1, RAB29, ZW10, KIF1C, KALRN, SEC22B, KDELR2, AP2S1, RAB38, TRAPPC12, USE1, VPS18, GOLT1B, SEC31A, GOSR1, COPB2, GDI2, RAB27A, COPB1, COPZ1, RAB1A, SYT13, BLZF1, RAB6B, STX8, MAPK8IP1, AP3B1, SEC16A, KDELR3, STX10, NSF, SEC24C, SEC13, RAB2A, CCZ1B, CCZ1, STX5, BVES, SCFD1, ERGIC2, KXD1, VTI1B, TRAPPC3, AP1G1, RTN3, SFT2D2, CHML, AP1S2, AP3S2, BNIP1, STX3, AHI1, MCFD2, VAMP8, STX18, TULP1, COPE, AP3D1, CNIH1, RAB6A, AP3M2, AP1S1, TRAPPC11, AP3S1, VPS33B, LMAN1, RAB32, KLHL12, STXBP6, ARL11, SEC22A, VPS45, ADAMTS9, AP2A2, SYT1, VAMP1, ARF1, ARF5, AP3B2, PICALM, CNIH3, TFG, ARL6, CHMP1A, TBC1D23, MYO5A, SYT5, KIF1B, STX17, CLINT1, ARFGAP1, SAR1B, AP1G2, TMED2, ARL14, ARAP3, AP2M1, GGA3, STX7, VAMP4, RAB14, ARF3, STX1B, GOLT1A, SYT12, SPTBN2, KIF5A, GOLGA4, VAMP3, TRAPPC3L, TRAPPC5, AP1S3, COPG1, STX16, BET1, TBC1D4, RHOBTB3, SEC24B, CLTA, TRAPPC10, BCAP31, AP2B1, SPIRE1, SEC23A, CP |
| vesicle-mediated transport in synapse | biological process | RAB11A, STX3, AP3D1, CPLX1, SCRIB, GRIP1, SNAP47, CLSTN1, RAB8A, NSG1, GRIP2, MAPK10, VPS35 |
| vestibular nucleus development | biological process | ASCL1 |
| vestibular reflex | biological process | SLITRK6, TMC1, NR4A3, TMC2 |
| vestibulocochlear nerve development | biological process | SLITRK6, CHRNB2 |
| vestibulocochlear nerve formation | biological process | NEUROG1, TIFAB, ATP8B1 |
| vestibulocochlear nerve structural organization | biological process | NRP2, NRP1 |
| viral budding | biological process | TSG101, CHMP5, VTA1, CHMP4B, NEDD4, PDCD6IP, MVB12A, LRSAM1, MVB12B |
| viral budding via host ESCRT complex | biological process | CHMP2A, TSG101, VPS28, VPS4B, CHMP4A, CHMP4B, CHMP1A, CHMP6, MITD1, VPS37C, VPS37A, PDCD6IP, VPS37B, CHMP4C, MVB12A, CHMP7, CHMP3, CHMP1B |
| viral capsid secondary envelopment | biological process | IST1 |
| viral entry into host cell | biological process | ICAM1, AXL, GAS6, ITGB1, ITGA5, ITGAV, CD46, HSPA1A, HSPA1B, NCAM1, DYNLT1, env, ACE2, CLDN6, ITCH, CD55, SLC1A5, VPS18, CLDN9, CTSB, ITGB5, CD81, LAMP3, SCARB2, VAMP8, KPNA3, TFRC, LDLR, IDE, EPS15, SCARB1, NUP153, MRC1, CD86, MOG, CD209, GRK2, ITGA2, ITGB6, TNFRSF4, ITGB3, HYAL3, NECTIN4, WWP2, GYPA, DPP4, SERPINB3, CXADR, WWP1, F11R, UVRAG, NPC1, CR2, RPSA, LAMP1, ITGB7, HYAL2, SELPLG, CLEC4G, TNFRSF14, NECTIN1, ZNF639, EPHA2, EFNB2, SIVA1, DAG1, EFNB3, CLEC5A, XPR1, CLDN1, PVR, SLAMF1, SLC52A2, SLC20A2, ANPEP, SLC52A1, CDHR3, CD80, TYRO3 |
| viral genome replication | biological process | GAS6, LAMTOR5, HTATSF1, DEK, KPNA6, CTBP2, NFIA, CD209, GRK2, CTBP1, CXCR6, CCL2 |
| viral life cycle | biological process | env, CHMP2A, TSG101, CHMP5, VPS28, VTA1, VPS4B, RPS27A, CHMP4A, CHMP4B, UBAP1, CHMP6, VPS37C, NEDD4L, UBC, UBA52, VPS37A, PDCD6IP, VPS37B, CHMP4C, MVB12A, CHMP7, FURIN, UBB, MVB12B, CHMP3, PPIA |
| viral mRNA export from host cell nucleus | biological process | THOC3, DDX39B, THOC7, THOC1, ALYREF, THOC2, THOC5, THOC6 |
| viral penetration into host nucleus | biological process | KPNA3, NUP153 |
| viral process | biological process | TP53, ICAM1, TNFRSF1A, IL6ST, BAX, HLA-B, HLA-A, SP1, ERCC2, MAPK3, MAPK1, CDC25C, AXL, KDR, STAT1, MDM2, GAS6, CASP8, HLA-DRA, ITGB1, ITGA5, VIM, STAT3, RAD23A, RB1, ITGAV, SRC, CD46, C1QBP, HSPD1, NCAM1, H2AFX, CCR5, SUMO1, BRD4, PSMA3, DYNLT1, PRMT6, env, HLA-C, TOP1, CCNA2, VDAC1, DYNLL1, ACE2, KPNA4, EED, HSPA8, PSMB1, PSMB5, RBL1, CLDN6, HNRNPU, UBE3A, IK, ELOC, TRAM1, NUP93, DDX1, OPTN, SPEN, YIPF4, DERL2, ACBD3, TBK1, RTRAF, DDX3X, PSMA7, EIF3D, CHMP2A, KIN, RNGTT, UBR5, NPM1, SLC25A4, CANX, PSMB2, KPNA2, GTF2A2, CXCR4, G3BP1, DYRK1A, KEAP1, KARS1, TAF5, PACS1, SRCAP, NUP37, ITCH, PSMB7, NUP88, TSG101, NUP85, IFIH1, VPS29, AP3M1, SUPT16H, TBKBP1, OGT, SGTA, CD55, HNRNPA1, XRCC5, IQGAP1, CAMLG, NUP107, SKP1, EIF4A2, SLC1A5, ZC3H12A, EIF3M, CARM1, PDZD8, NUP43, POM121, RBM15, NCKAP1, HCFC2, IVNS1ABP, KPNA5, PSIP1, CPSF4, PIK3R1, SHC1, COPB1, PLAAT3, NFX1, TRIM25, TENT5C, COPS6, WAPL, NLRX1, NUP35, DTX3L, FBXW7, DERL1, NUP58, DNAJB12, BTRC, XPO1, MAP3K7, SYNCRIP, CCNT1, PRKRA, VAPB, CLDN9, STAU1, ITGB5, |
| viral protein processing | biological process | env, SPCS3, SPCS1, FURIN |
| viral release from host cell | biological process | VPS4B, IST1, PPID, RAB7A, PPIA |
| viral replication complex formation and maintenance | biological process | PI4KA |
| viral RNA genome packaging | biological process | PC, DDX6 |
| viral RNA genome replication | biological process | RAB29, PCBP1, ROCK2, RAB5A, EEA1, PCBP2, PI4KA |
| viral transcription | biological process | RPL4, RPL3, RPL5, RPS10, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, RPL24, RPL6, NUP93, RPLP0, RPL29, RPL15, RPS8, RPL7A, RPL32, RPS21, NUP37, NUP88, NUP85, RPL7, RPL13, NUP107, RPS18, RPS13, RPL11, RPL19, NUP43, POM121, RPL35A, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, NUP35, NUP58, RPS2, RPL9, RPS19, RPS5, SEC13, RPS25, RPL30, RPS27A, RPL38, NUP205, NUP50, RPS3, NUP62, RPL13A, RPL35, RPLP1, RPS12, RPS27, RPL39, NUP155, RPS4Y1, RPL8, NUP153, RAE1, SEH1L, RPL27A, RPL18A, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, RPL14, RPL37, RPS15A, RPS24, RPS28, NUP133, RPL36, RPL10, RPLP2, RPS17, RPL23A, RPL18, NUP54, TPR, RANBP2, NUP98, UBA52, RPSA, RPS11, RPL36A, RPL17, RPL23, RPL26, AAAS, NUP210, NUP188, NUP42, NUP214, NUP160 |
| viral translational frameshifting | biological process | SHFL |
| viral translational termination-reinitiation | biological process | EIF3D, EIF3L, EIF3G, EIF3A, EIF3B |
| virion assembly | biological process | APOE, env, USP6NL, RAB1A, SPCS1, RPS27A, TBC1D20, UBC, UBA52, UBB, RAB1B, PPIA |
| virion attachment to host cell | biological process | env, CD209, NECTIN1 |
| virus maturation | biological process | MVB12A, MVB12B |
| visceral motor neuron differentiation | biological process | ISL1, TBX20 |
| visceral muscle development | biological process | MYH6 |
| visceral serous pericardium development | biological process | WT1, HAND2 |
| visual behavior | biological process | NPHP1, NPHP4, DYNLRB1, SLC1A2 |
| visual learning | biological process | HIF1A, APP, ITGB1, MTOR, KIT, B4GALT2, PIAS1, NPTN, GRIN1, CTNS, KRAS, HRH1, NDRG4, PPP1R1B, SYNPO, HMGCR, DEAF1, DDHD2, PDE1B, ATP1A2, MECP2, ADAM2, TAFA2, DRD3, FOXB1, MEIS2, DRD1, CCK, CDK5, GRIN2A, RGS14, CHRNB2, HRH2, RIC8A, DBH, DRD2, LRRN4, NF1, NETO1, TANC1 |
| visual perception | biological process | CYP1B1, WFS1, COL11A1, KCNJ10, NDP, BBS2, OPA3, ZIC2, RCVRN, PPT1, CRYBA4, RPGRIP1, NYX, GJD2, AOC2, DHRS3, CRYGA, BBS5, PPEF2, PDE6D, PITPNA, PDCL, RIMS1, RPGR, RGS16, CRYGS, RABGGTB, TULP1, TIMP3, ABCA4, OPN5, MKKS, VSX1, PCARE, GRM8, BBS9, ABLIM1, USH2A, COL2A1, GNAT2, RP1, MYO3B, ARL6, MYO5A, TULP2, OPA1, PDE6A, UNC119, WDR36, DNAJC19, BBS4, GUCY2F, CNNM4, MFRP, IMPG2, SLC45A2, NR2E3, TYR, NOB1, MYO9A, GUCA1A, CRYBA1, SLITRK6, SIX3, OAT, EYA4, TACSTD2, CRYZ, FAM161A, DRAM2, ADGRV1, KIFC3, CRB1, TGFBI, CLIC5, IRX5, EPAS1, CNGB3, CABP1, EML2, CRYGD, ROM1, GJA3, GLRA1, NRL, MYO3A, CRYGN, RAX2, VAX2, GRM6, TH, PDE6G, GUCY2D, NXNL2, RDH10, ZNF513, AIPL1, CRX, RLBP1, GABRR2, COL18A1, CRYBA2, CRYBB1, SFRP5, RD3, RDH5, RDH12, RDH8, RAX, LAMC3, SIX6, CRYAA, LCTL, HPS1, RBP4, CHRNB2, CDH3, CABP4, CNGB1, PRR4, GRK7, FSCN2, ABCC6, PDE6B, MYO7A, TRPM1, CABP2, HSF4, ATXN7, OLFM2, RHO, GPR143, PRCD, GRK1, RP1L1, BBS1, CDH23, OPN4, RGS9, CRYBB2, BFSP2, EYS, KERA, RP2, GUCA1C, GJC1, CACNB2, RPE65, CRYBG3, SLC4A10, RGS9BP, |
| visual system development | biological process | P2RY12 |
| vitamin A biosynthetic process | biological process | BCO1 |
| vitamin A import | biological process | STRA6 |
| vitamin A metabolic process | biological process | ALDH1A2, PPARD, RBP1, RBP2, RLBP1, RPE65 |
| vitamin B6 metabolic process | biological process | PDXK, AOX1, PNPO |
| vitamin D biosynthetic process | biological process | CYP2R1, CYP27B1 |
| vitamin D catabolic process | biological process | CYP24A1, FGF23, CYP27B1 |
| vitamin D metabolic process | biological process | CYP1A1, CYP24A1, CYP11A1, GC, CYP2R1, LGMN, FGF23, LRP2, CYP27B1, PIAS4, CUBN |
| vitamin D receptor signaling pathway | biological process | VDR, CYP24A1 |
| vitamin E metabolic process | biological process | TTPA, CYP4F12, CYP4F2 |
| vitamin K biosynthetic process | biological process | UBIAD1 |
| vitamin K catabolic process | biological process | CYP4F3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| vitamin K metabolic process | biological process | UBIAD1, CBR1, VKORC1L1, VKORC1 |
| vitamin metabolic process | biological process | CYP24A1, CYP26B1, CYP2R1, CYP26A1, LRP2, CYP27B1, CYP26C1 |
| vitamin transmembrane transport | biological process | ABCC1, SCARB1, C2orf83 |
| vitamin transport | biological process | AFM, GC, SLC19A3, C2orf83, APOA1, TTPA, SLC19A2 |
| vitelline membrane formation | biological process | IHH |
| vitellogenesis | biological process | SOS1, ZMIZ1 |
| vocal learning | biological process | NRXN2, CNTNAP2, FOXP2, HTT, STRA6 |
| vocalization behavior | biological process | GLI3, MYH14, NLGN4X, NRXN1, SRPX2, NRXN2, SHANK2, NRXN3, CNTNAP2, NLGN4Y, DLG4, BRINP1, SHANK1 |
| voluntary musculoskeletal movement | biological process | MTOR, HIPK2, ITPR1, VTI1A, VPS35 |
| walking behavior | biological process | PSAP, SPG11 |
| water homeostasis | biological process | AQP11, AQP9, GHRHR, NEDD4L |
| water transport | biological process | AQP5, AQP7, AQP2, SLC14A1, AQP11, AQP9, PDZD3, AQP3, AQP1, AQP6, PDPN, AVP, AQP10, UPK3A |
| wax biosynthetic process | biological process | FAR1, FAR2 |
| white fat cell differentiation | biological process | PPARG, AACS, CTBP2, PER2, ADIG, CTBP1, PRDM16, FGF10 |
| Wnt protein secretion | biological process | WLS |
| Wnt receptor catabolic process | biological process | RNF43, ZNRF3 |
| Wnt signaling pathway | biological process | NDRG2, GSK3B, CSNK2A2, CTNNB1, CSNK2B, PYGO2, TCF7L2, ETV2, SNX3, RYK, TCF7, ROR1, SENP2, DDX3X, VPS26A, GRK5, DDIT3, CSNK1A1, NDP, TLE1, FERMT2, CUSTOS, VPS29, LRRFIP2, FZD9, SKP1, XIAP, WDR61, CALCOCO1, CDK14, PTK7, CPZ, MARK2, CCNY, ADGRA2, LGR4, FZD8, TCF7L1, CTNNBIP1, FZD4, BTRC, BCL9, CSNK1E, RPS27A, WLS, DVL1, SLC9A3R1, HBP1, TNKS, PAF1, WNT10A, MACF1, CTNND1, WNT7B, DAB2, CUL1, UBAC2, RNF138, WNT4, FZD2, KLHL12, AMER3, RTF1, FRZB, DISC1, WNT9B, CCND1, WNT3A, ARL6, FZD3, TMEM131L, MITF, PKD2, RNF43, CTR9, VRK2, DRAXIN, OTULIN, KREMEN1, TGFB1I1, DKK1, CSNK1D, WNT2B, WNT8B, AXIN1, FZD7, LRP6, CDC73, RSPO2, CELSR2, AMOTL2, WIF1, STRN, CCNE1, MESD, VRK3, TNKS2, APC, CSNK2A1, TLE4, SOSTDC1, CCAR2, CYLD, NLK, TNIK, CTNND2, DVL2, TSPAN12, CSNK1G2, GID8, CCDC88C, TRABD2B, UBC, GRK6, CSNK1G1, HMGXB4, PYGO1, PRKAA2, UBA52, NXN, USP34, ZRANB1, LEF1, INVS, TLE2, FAM53B, LMBR1L, NPHP3, ZBTB33, RSPO3, DACT1, LRP5, WNT11, AMER1, AMER2, SFRP2, ZBED3, LZTS2, DKK4, VAX2, GPC4, CPE, RAC3, RBX1, FZD5, HIC1, DAAM2, DVL3, A |
| Wnt signaling pathway involved in dorsal/ventral axis specification | biological process | EGF |
| Wnt signaling pathway involved in forebrain neuroblast division | biological process | WNT3A |
| Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation | biological process | RYK, WNT3A, LRP6, FZD1 |
| Wnt signaling pathway involved in somitogenesis | biological process | PPP2R3A, DKK1, LRP6, SFRP2 |
| Wnt signaling pathway, calcium modulating pathway | biological process | GNAO1, CTNNB1, TCF7L2, AGO4, FZD4, MAP3K7, NFATC1, PPP3CB, GNB1, FZD2, AGO3, GNAT2, FZD3, PDE6A, PLCB2, PLCB3, CALM1, GNG2, PPP3CA, NLK, AGO2, TNRC6B, TNRC6A, TNRC6C, LEF1, MOV10, WNT11, AGO1, PDE6G, PPP3R1, FZD5, FZD6, PDE6B, ROR2, CAMK2A |
| Wnt signaling pathway, planar cell polarity pathway | biological process | CDC42, PSMA3, PSMB1, PSMB5, PSMC2, ROR1, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, PSMB7, AP2S1, PSMD6, PSMD1, PSMD14, PSMD7, FZD4, PSMB6, DVL1, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, PSMB8, PSMD4, FZD2, WNT9B, AP2A2, PSMC3, PSMA6, FZD3, GPC6, PRICKLE2, AP2M1, FZD7, CELSR2, CELSR1, TIAM1, VANGL2, PSMD12, PSMB9, PSMC4, RAC1, AP2B1, PSMD9, DVL2, PSMA4, PSMD2, CLTC, PARD6A, PSMD5, PSMF1, PSMB3, WNT11, MED12, PSMD3, GPC4, PSMC1, FZD5, DVL3, SMURF2, FZD6, VANGL1, CTHRC1, PRICKLE1, AP2A1, ARRB2, ROR2, CELSR3, FZD1, WNT7A, PSMD13, PSMB10 |
| Wnt signalosome assembly | biological process | LRRK2 |
| wound healing | biological process | TIMP1, TGFB1, IL1B, IL6, DCN, TGFB3, IGF2, ERBB2, CASP3, MTOR, BMP4, MMP12, NRG1, PLAU, FN1, RAF1, TPM1, CX3CL1, GLI3, NACA, CORO1B, HPSE, PTK7, PPARD, PLEC, DCBLD2, MACF1, COL3A1, SERPINB2, SCARB1, KRT6A, SDC4, SPRR3, DST, SCRIB, POSTN, ITGA2, ELK3, CELSR1, EREG, CFLAR, PDGFA, DSP, ITGB3, LOX, TGFB2, VANGL2, PPP3CA, MAP3K5, B4GALT1, TNC, TGFBR1, EPPK1, MIA3, EPB41L4B, FGFR1OP2, PPL, S100A8, SMAD2, C6orf89, SLC11A1, NOTCH4, ERBB3, P2RY1, EVPL, PDGFRB, MSX2, TGFBR2, ITGA9, FGF2, PDGFRA, PECAM1, ENG, IL24, CDH3, INS, PPARA, EVPLL, WNT7A, FGF1, SDC1, NF1, SMAD3, GRHL3, WNT5B, MYOZ1, FGF10 |
| wound healing involved in inflammatory response | biological process | HMOX1 |
| wound healing, spreading of cells | biological process | DDR1, CCN1, PDCD10, ARHGAP35, MRTFA, CD151, LCP1, PDPN, CEACAM1, TMEFF2, RHOC, CARMIL2 |
| wound healing, spreading of epidermal cells | biological process | ITGA5, MMP12, AJUBA, ARHGAP24, HBEGF, COL5A1, MSX2, ACVRL1, WNT7A |
| wybutosine biosynthetic process | biological process | TYW3, TRMT12, TYW5, LCMT2, TYW1B, TYW1 |
| xanthine biosynthetic process | biological process | ADA |
| xanthine catabolic process | biological process | XDH, AOX1 |
| xanthophyll metabolic process | biological process | BCO2 |
| XDP catabolic process | biological process | NUDT16 |
| xenobiotic catabolic process | biological process | GSTM1, ACSL1, GSTO1, CRYZ, GSTM4 |
| xenobiotic detoxification by transmembrane export across the plasma membrane | biological process | SLC17A3, RALBP1, SLC15A2, OSCP1 |
| xenobiotic glucuronidation | biological process | UGT1A8, UGT2B11, UGT2B28, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10 |
| xenobiotic metabolic process | biological process | PTGS1, AHR, NR1I2, CYP1A2, NAT2, CYP2B6, S100A12, GSTP1, MGST1, SULT1A1, EPHX2, CYP1B1, CYP2J2, PTGES3, CYB5B, MGST3, AOC2, MGST2, AIP, AKR7A2, CES1, CYP2R1, CBR3, GLYAT, UGT2B11, NAT1, GUK1, NQO1, POR, CYP2A7, GSTA1, CYP2C8, AADAC, CYP26A1, RORA, MTARC2, CYP2A6, FMO3, CYP2C19, GSTO2, UGT2B15, AOC1, CYP3A5, CYB5R3, CYP2C18, SULT1B1, GSTA3, HNF4A, AKR7L, SULT1A3, AOC3, ACY3, CMBL, CYP2E1, CES2, NQO2, GGT1, SULT1A2, CYP46A1, AHRR, CYP2D6, CYP2S1, CYP2D7, RORC, ACSM1, CYP2W1, UGT1A9, DPEP1, UGT1A6, GSTA4, GSTA2, FMO1, AKR1C1, EPHX1, CYP2C9, MTARC1 |
| xenobiotic transport | biological process | NR1I2, ABCB1, SLC22A2, SLC15A2, SLC47A1, ABCC3, EBP, SLC47A2, SLC22A4, ABCC5, ABCC4, SLC22A1, SLC22A3 |
| xenobiotic transport across blood-brain barrier | biological process | SLC22A2, SLC22A1, ABCG2 |
| xenobiotic transport across blood-nerve barrier | biological process | CLDN1 |
| xenophagy | biological process | DPF3, ANXA5, LGALS8, WIPI2, CALCOCO2 |
| xylulose biosynthetic process | biological process | TALDO1, TKT |
| xylulose catabolic process | biological process | XYLB |
| xylulose metabolic process | biological process | DCXR, XYLB |
| zeaxanthin biosynthetic process | biological process | RPE65 |
| zinc ion homeostasis | biological process | PRKN, ATP13A2, MT3, TMC8, SLC30A4 |
| zinc ion import across plasma membrane | biological process | SLC39A12, SLC39A10, SLC39A5, SLC39A8, SLC39A6, SLC39A4, SLC39A14 |
| zinc ion import into synaptic vesicle | biological process | TMEM163, SLC30A3 |
| zinc ion transmembrane transport | biological process | SLC30A5, SLC30A2, SLC30A10, SLC30A8, SLC39A11, SLC39A8, SLC30A1, SLC39A6, SLC39A13, SLC39A3, SLC30A3, SLC30A6, SLC39A1, TRPM2, SLC39A14, SLC30A4, SLC39A7 |
| zinc ion transport | biological process | SLC30A9, SLC30A5, SLC39A9, SLC30A2, SLC39A12, SLC30A10, SLC39A10, SLC39A5, SLC30A8, SLC39A11, SLC39A8, SLC30A1, SLC39A6, SLC39A13, SLC30A7, MT3, SLC39A3, SLC30A3, SLC30A6, SLC39A4, SLC39A1, SLC39A14, SLC30A4, SLC39A7 |
| zonula adherens assembly | biological process | DLG5, ABI2 |
| zonula adherens maintenance | biological process | KIFC3, CAMSAP3 |
| zygote asymmetric cell division | biological process | RGS14 |
| zygotic determination of anterior/posterior axis, embryo | biological process | PCSK6 |
| zygotic specification of dorsal/ventral axis | biological process | SMAD6, SMAD2 |
| zymogen activation | biological process | OMA1, F12, PRSS12, HGFAC, MMP14, KLK2, PRSS3, C1R, KLK1, FURIN, GGT1, CTSH, VSIR, C1RL |
| zymogen inhibition | biological process | FURIN |
| [2Fe-2S] cluster assembly | biological process | GLRX3, NFS1, HSCB, BOLA2 |
| 3-methylcrotonyl-CoA carboxylase complex, mitochondrial | cellular component | MCCC1, MCCC2 |
| 3M complex | cellular component | OBSL1, ANKRA2, CUL7, FBXW8, CCDC8 |
| 4-aminobutyrate transaminase complex | cellular component | ABAT |
| 6-phosphofructokinase complex | cellular component | PFKM, PFKP, PFKL |
| 9+0 non-motile cilium | cellular component | IFTAP, TULP3, PHYH, PRLHR, ARL13B, C1orf115, MCHR1, SMO, TTLL6, TTLL4, IFT80, C4orf47, NMUR1, DRD1, SSTR3, DYNLL2, GALR3, NPY5R |
| 9+2 motile cilium | cellular component | DNALI1, RSPH9, GAS8, ENKUR |
| 90S preribosome | cellular component | NOP14, UTP4, HEATR1, UTP20, KRI1, MRPL1, FAM207A, TBL3, RSL1D1, BMS1 |
| A band | cellular component | ANK1, HDAC4, PPP1R12A, MYL4, MYBPC3, MYH1, ANK2, PPP1R12B, MYL2, KLHL40, KAT2B, MYL3, S100A1 |
| acetylcholine-gated channel complex | cellular component | CHRNA5, CHRNE, CHRNA2, STXBP5, CHRNB1, CHRNA7, CHRND, CHRFAM7A, CHRNA3, CHRNA6, CHRNG, CHRNB2, CHRNA4, CHRNA1, CHRNB4 |
| ACF complex | cellular component | BAZ1A |
| acrosomal matrix | cellular component | ACR, CYLC1 |
| acrosomal membrane | cellular component | SERPINA5, IZUMO1, SPACA1, SPACA3, TEKT3, TEX101, CFAP65, ATP8B3, RND2, CAV2, PCSK4, ACRBP, TRIP11, HYAL3, EQTN, PLA1A, CAV1, CCDC136 |
| acrosomal vesicle | cellular component | ATP6V0A2, ITGB1, HEXB, ACR, KIT, CD46, TXNDC8, IZUMO1, CLK3, SPACA3, CATSPER4, CATSPER3, SPINK1, CAPZA3, SKIL, GLIPR1L1, CFAP65, PLA2G10, ATP8B3, KIAA1210, SPACA4, STK31, TCP1, CTNNA1, DPEP3, GOLGA1, SH3GL3, IQUB, SPACA9, VEZT, CEP131, NOTCH1, ABHD2, NUDT1, PCSK4, MROH2B, ACRBP, HYAL3, RCBTB2, CXADR, ZPBP2, SCNN1A, BMF, PPFIA3, SV2B, LRGUK, POMT1, ENKUR, ATP6V1E2, DRD2, TBXA2R, CALR, CRCP, VDAC2, TEX101, FNDC3A |
| actin cap | cellular component | WASL, CALD1, ACTR2 |
| actin cortical patch | cellular component | WIPF3 |
| actin cytoskeleton | cellular component | APOB, CDH1, EZR, TWF1, 39326, MYRIP, WASL, ZNF174, DSTN, SEPTIN2, USH1G, ARPC1A, ALG2, SEPTIN9, DENND2A, ACTR3, TAF5, PALLD, PAWR, BAIAP2L1, BAIAP2, PPP1R12A, ARPC3, KALRN, IQGAP1, IQGAP2, MSRA, ACTL7B, SCIN, ARHGAP32, CIT, SVIL, HNRNPC, DMD, ABRA, RFLNB, AUTS2, PPP1R9B, PEAK1, CTTNBP2NL, TPM3, NEB, CTNNA1, SNCA, VASP, MYO5C, CORO1C, SLC9A3R1, ARPC5, WIPF1, FLNB, STK17B, CAPZA1, NEXN, CNN3, SPECC1L, MACF1, HAX1, ARHGAP35, PDLIM1, ZNF185, RAB5A, CTNNA2, TARS1, ZNF268, RINL, MAEA, SYNPO, SWAP70, TAOK2, CLIC4, ABLIM1, BCAR1, TOPBP1, C10orf90, AIF1L, KANSL2, ANLN, STOML2, RAB22A, CFL2, MYO5A, ACTC1, STK38L, MTSS1, DST, CALD1, SPPL2B, LIMA1, TLN2, ALDOA, GBP2, AMPH, AHNAK, FILIP1, CDC42EP3, MYO6, NPFFR2, ONECUT2, CDC42EP4, FSCN3, ACTL7A, ESPN, SORBS2, CNR1, SYNPO2, IPP, KLHL2, GBP1, ADCY8, ARHGAP21, ACTL9, WASF2, FYB1, MYO1B, ABL1, FER, CAPZA2, ACTG1, PKNOX2, PARVG, KLHL20, ARHGAP6, GABARAP, VCL, ABCB4, AKAP13, ANKRD23, GAS2L3, ACTRT3, PARVB, CLIC5, MYO5B, EFR3B, H1-0, ABL2, CAPZB, ACTR2, DGKH, WASF1, PDLIM5, TRIO |
| actin filament | cellular component | YES1, SRC, EZR, AIF1, WIPF3, CORO1B, COBL, DYRK1A, COTL1, KEAP1, PALLD, PAWR, ACTL8, IQGAP1, VPS18, MARK2, TPM3, WIPF1, WDR1, PLS1, RCSD1, ANXA1, TSC1, ABI2, TPM4, CTTN, GDPD2, AMOT, AIF1L, MYO5A, ACTC1, TEK, ACTN2, POF1B, DBNL, MYO6, RHOQ, GAS2L1, ACTN1, RAC1, MYO1B, RAC2, ACTG1, ARHGAP6, AKAP13, GAS2L3, HCLS1, LCP1, GNG12, TIGD5, TWF2, GAS2L2, WIPF2, AVIL, HCK, WAS, ACTN3, DMTN, GJB6, CORO1A, GAS2, APC2, TPM2, MISP, MYO9B, ACTBL2, LMOD2, WHRN, TMOD1, SPTBN4, BIN3, LMOD1, FMN1, ACKR2 |
| actin filament bundle | cellular component | RFLNB, CRYAB, PLS1, LCP1, MARCKS, MICALL2, RFLNA, VIL1 |
| actin-based cell projection | cellular component | MYO1F |
| activating signal cointegrator 1 complex | cellular component | ASCC3, TRIP4, ASCC2 |
| activin A complex | cellular component | INHBA |
| activin receptor complex | cellular component | ACVR1B, ACVR1, ACVR2B, ACVR1C, TGFBR1, ACVR2A |
| activin responsive factor complex | cellular component | SMAD4, SMAD2, FOXH1 |
| actomyosin | cellular component | HDAC4, MYH10, MYH14, MYO5A, MYO18A, PDCD6IP, CDC42BPB, MYH9, KAT2B |
| actomyosin contractile ring | cellular component | MAEA, ANLN, RTKN, MYH9 |
| actomyosin, actin portion | cellular component | WDR1, ACTC1 |
| Ada2/Gcn5/Ada3 transcription activator complex | cellular component | TADA3, HCFC2, DR1, POLE3, MAP3K7, MBIP, HCFC1, WDR5, ZZZ3, SGF29, POLE4, KAT2A, KAT2B, KAT14, YEATS2, UBAP2L |
| adherens junction | cellular component | ITGB1, CTNNB1, NPHP1, SYNM, NF2, SHROOM3, SORBS1, WNK3, EIF4G2, BAIAP2L1, BAIAP2, TJP1, CDH7, SNAP23, CYTH3, PPP1R9B, CTNNA3, CTNNA1, DLG5, JCAD, NEXN, CNN3, AHI1, CDH10, CTNND1, ANXA1, CDCA3, CDH19, ABI2, PDLIM1, ARVCF, CTNNA2, MPP7, STXBP6, AJUBA, PDLIM2, LRRC1, VEZT, NOTCH1, ARHGAP24, PARD3B, TMEM204, AJM1, KRT18, EFNA5, SCRIB, KLHL24, POF1B, PKP4, TMEM47, CD99L2, PARD3, CCDC85A, FRMD4B, CDH12, PGM5, CDC42EP4, EPB41L5, FLOT1, APC, CDC42EP1, CDH17, SDCBP, PTPRM, NECTIN4, CTNND2, CXADR, MAGI1, KIFC3, FRMD4A, SSX2IP, WTIP, VCL, CRB1, FRS2, EPHA4, PDLIM5, TMOD3, LDB3, CDH6, ESAM, PKP2, PDLIM7, NECTIN1, CYTH2, TBCD, CDH9, PAK4, CEACAM1, CDH5, ADD1, EFNB2, CDH8, CDH11, CDH13, DSC2, NDRG1, LIMD1, PLPP3, JUP, PDLIM4, TRIM29, PDLIM3, DLL1, PVR, MYH9, FRMD5, CCDC85C, ALOX15B, CDH3, CDH4, CDH15, PKP3, TLN1, PIP5K1C, JAG1, SHROOM2, FAT2, AJAP1, SH3BP1, CDH24, CDH23, SPTBN4, CAMSAP3, CYTH1, FMN1, CDHR3, CDH26, IGSF21, NIBAN2, AFDN, CCDC85B, ZYX, MPP4, TNKS1BP1 |
| adrenomedullin receptor complex | cellular component | CALCRL, RAMP2, RAMP3 |
| aggresome | cellular component | CLU, CDH1, HOXD3, TRIM37, URB2, ZDHHC17, PRKN, STRADB, XRN2, UBD, BAG3, EPS15, PSAP, EEF2, PRKCQ, HOXC9, PSEN1, SQSTM1, DVL2, TDP2, ABI1, DBF4B, HDAC6, FGR, ZBTB14, KLF8, EDEM1, PRDM16, POLD1, CABIN1, TRIM66, SFMBT2, HSPA1A, HSPA1B, HSPB7 |
| AIM2 inflammasome complex | cellular component | CASP1, CASP4, AIM2, PYCARD |
| AIP1-IRE1 complex | cellular component | DAB2IP, ERN1 |
| alpha DNA polymerase:primase complex | cellular component | MCM3, PRIM2, PRIM1, POLA2, POLA1 |
| alpha-beta T cell receptor complex | cellular component | PTPN6, CD3E, CD3G, CD247 |
| alpha9-beta1 integrin-ADAM8 complex | cellular component | ADAM8 |
| alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex | cellular component | VCAM1, ADAM8 |
| alphav-beta3 integrin-HMGB1 complex | cellular component | HMGB1, ITGB3 |
| alphav-beta3 integrin-IGF-1-IGF1R complex | cellular component | IGF1, ITGAV, IGF1R, ITGB3 |
| alphav-beta3 integrin-PKCalpha complex | cellular component | ITGB3 |
| alphav-beta3 integrin-vitronectin complex | cellular component | ITGA5, ITGB3, VTN |
| alveolar lamellar body | cellular component | SFTPB, LAMP1, SFTPC, ABCA3, CTSH, NAPSA |
| alveolar lamellar body membrane | cellular component | LAMP3, ABCA3 |
| amino acid transport complex | cellular component | SLC3A2 |
| aminoacyl-tRNA synthetase multienzyme complex | cellular component | KARS1, MARS1, EPRS1, IARS1, AIMP2, EEF1E1, RARS1, LARS1, AIMP1, QARS1 |
| AMPA glutamate receptor complex | cellular component | ABHD12, CACNG2, CACNG3, CACNG7, CNIH3, GRIA2, DLG4, CACNG4, DLG3, ABHD6, GRIA3, CNIH2, VWC2, CPT1C, GRIA1, OLFM2, SHISA7, VWC2L, SHISA6, OLFM3, CACNG8 |
| amphisome | cellular component | SQSTM1, LRRK2 |
| amylin receptor complex 1 | cellular component | RAMP1, CALCR |
| amylin receptor complex 2 | cellular component | RAMP2, CALCR |
| amylin receptor complex 3 | cellular component | RAMP3, CALCR |
| anaphase-promoting complex | cellular component | CDC20, CDC16, CDC23, ANAPC15, FZR1, ANAPC16, BUB1B, ANAPC5, ANAPC7, CDC20B, ANAPC11, ANAPC13, MAD2L2, CDC27, CUL7, CDC26, ANAPC1, UBE2C, ANAPC4, ANAPC2, UBE2S |
| anchored component of external side of plasma membrane | cellular component | PRNP, RTN4R, CD59, GPIHBP1, EFNA5, HYAL2, FOLR3, THY1, PKHD1, GP1BA, CA4, IGSF21, FOLR1 |
| anchored component of membrane | cellular component | SEMA7A, PLAUR, CD52, GFRA1, NCAM1, SPAM1, ART3, TEX101, PRNP, ALPP, GLIPR1L1, CNTN4, GPC2, CPM, CD55, ALPI, MDGA1, TNFRSF10C, TFPI, TDGF1, BST2, SPACA4, RTN4R, DPEP3, EFNA1, GPC5, ART4, RGMA, CNTN5, LY6G6C, CD59, GAS1, BCAN, CNTFR, NRN1L, HJV, NEGR1, LYPD6, GPIHBP1, NTNG1, GPC6, LY6G6D, NT5E, CEACAM8, CNTN2, CNTN1, ZFAND2B, XPNPEP2, UMOD, EFNA5, GP2, OPCML, LYNX1, CEACAM6, CEACAM7, LY6E, GML, NTM, CD48, LYPD4, LSAMP, TREH, TECTA, RGMB, PRSS21, NTNG2, EFNA2, SVIP, DNAJC5, FCGR3B, LYPD6B, MMP25, VNN2, HYAL2, SMPDL3B, PSCA, LYPD3, VNN1, ITLN1, ULBP3, VNN3, GPC4, CDH13, BST1, ULBP2, DPEP2, NRN1, CD109, GFRA3, CD160, THY1, GPC1, LY6D, RTN4RL2, ULBP1, GPC3, MSLN, GFRA2, LY6H, ALPL, MELTF, MMP17, CA4, ENPP6, DPEP1, EFNA3, ART1, MDGA2, RTN4RL1, IGSF21, GFRA4, CNTN6, RECK, GAD2, SPRN, LYPD5, LYPD8, FOLR1, OTOA, CNTN3 |
| anchored component of plasma membrane | cellular component | GPC2, MDGA1, EFNA1, GPC5, RHBG, GAS1, NRN1L, NOD2, NTNG1, GPC6, LYPD4, TREH, RGMB, NTNG2, CD2, HYAL2, LYPD3, ULBP3, GPC4, ULBP2, CD160, THY1, GPC1, RTN4RL2, ULBP1, GPC3, NOD1, MELTF, CA4, EEPD1, RTN4RL1, FOLR1, TEX101 |
| anchored component of postsynaptic density membrane | cellular component | ABHD17B, ABHD17A |
| anchored component of postsynaptic membrane | cellular component | CNTN2, CNTN1 |
| anchored component of postsynaptic recycling endosome membrane | cellular component | ABHD17B, ABHD17A |
| anchored component of presynaptic active zone membrane | cellular component | NTNG1, NTNG2, CPLX3 |
| anchored component of presynaptic membrane | cellular component | CNTN5, CNTN1, GPC4, CNTN6 |
| anchored component of synaptic vesicle membrane | cellular component | RAB4A, RAB3C, RAB5A, RAB35, RAB27B, SYN1, RAB3B, RAB11B, RAB26, DNAJC5, RAB5B, CPLX3 |
| anchored component of the cytoplasmic side of the plasma membrane | cellular component | PRMT8 |
| angiogenin-PRI complex | cellular component | RNH1, ANG |
| annulate lamellae | cellular component | XPO1, NUP62, EIF5A, TNPO3, BICD2, RANBP2 |
| AnxA2-p11 complex | cellular component | S100A10 |
| AP-1 adaptor complex | cellular component | SYNRG, AP1G1, AP1S1, SLC18A3, AP1G2, AFTPH, CLBA1 |
| AP-2 adaptor complex | cellular component | EGFR, AP2S1, EPS15, AP2A2, PICALM, SLC18A3, AP2M1, AP2B1, TBC1D5, AP2A1, SGIP1 |
| AP-4 adaptor complex | cellular component | AP4S1, AP4M1, AP4B1, TEPSIN, AP4E1 |
| AP-5 adaptor complex | cellular component | AP5Z1 |
| AP-type membrane coat adaptor complex | cellular component | AP5M1, AP5Z1, AP5S1, AP1S2, AP3M2, AP3S1 |
| apical cortex | cellular component | PRKCZ, MYO5B, OOEP, TCHP, HAMP, SAPCD2 |
| apical cytoplasm | cellular component | LRRC6, SNX10, MYO7B |
| apical dendrite | cellular component | FAS, CLU, NSMF, NEURL1, PPARGC1A, OSBP2, CPEB3, YKT6, ITSN1, SEZ6, MYO1D, PTK2B, MAP1B, SLC4A10 |
| apical distal dendrite | cellular component | MAP2 |
| apical ectoplasmic specialization | cellular component | ATP2A2 |
| apical junction complex | cellular component | CTNNB1, CDH1, SHROOM3, FRMD6, TJP1, PARD3B, PKN2, PDZD3, PARD3, ACTG1, NECTIN1, CCDC85C, SHROOM2, FBF1, SAPCD2 |
| apical part of cell | cellular component | APP, MGST1, CTNNB1, HFE, PLAT, EZR, CDC42, ACPP, NF2, DYNC2H1, ADCY10, CA2, SIPA1L3, PCM1, TJP1, NEDD1, VCAM1, NIN, MYL12B, CTSV, NUMB, DYNC2LI1, SLC9A3R1, ACVR1, DCHS1, LGMN, LDLR, CLIC4, FZD3, HOMER2, EMP2, USH1C, ITPR3, PDZD3, MYO6, CHL1, LRP2, REEP6, TUBG1, MSN, AMN, DVL2, MYO1B, VAMP7, ATP6V1C1, RDX, EPB41L4B, HOMER1, SVBP, PARD6B, DUOXA2, ATP6V0A4, DUOX2, AQP1, DRD3, LRP1, C5AR2, EDA, ATP2B1, ENPEP, EDAR, FZD6, SRR, JAG1, PTCH1, ARHGEF18, VASH1, ABCB11, CRB3, CUBN, DPEP1, ADGRF5, CLCN5, SLC4A9, CD36, C5AR1, ITGA8 |
| apical plasma membrane | cellular component | IL6R, FAS, ERBB2, HSP90AA1, CFTR, CIB1, TF, PTEN, CLCA4, MUC1, SLC7A5, NRG1, BMPR2, SLC22A18, MUC13, FN1, EZR, GJA1, CD9, OXTR, AQP5, 39326, SLC6A20, SLC22A5, PIP, KISS1, MYRIP, ANXA6, SLC19A1, SLC26A4, SIPA1L3, ATP6V1B1, SLC2A5, SLC26A3, AQP2, P2RY4, SLC5A8, SHROOM3, RAB18, PFKM, ATP6V1B2, MLC1, SLC30A5, SLC22A2, ATP6AP2, CTSK, SLC12A2, CYP4A11, FAT1, SLC44A4, SLC17A3, KCNK2, TDGF1, EPCAM, RAB27A, BST2, RAPGEF2, MGAM, CTSL, CTSB, SI, PTH1R, PLD1, SLC9A3R1, MPDZ, AKR1A1, PTK2, STX3, SLC22A12, SLC4A7, HAX1, FXYD1, ANXA1, CD34, ATP6V1E1, SLC15A2, MFSD4B, CSPG4, ASPM, RAPGEF6, PLPP1, AHCYL1, EPS15, SLC5A12, CD300LG, ENPP3, USH2A, SLC9A1, CNTFR, ATP6V1A, NOTCH1, SLC26A9, GPIHBP1, PARD3B, FZD3, NAALADL1, AJM1, RAB27B, HPN, ADRB2, LCT, CYBA, EMP2, TEK, SLC17A1, PAPPA2, UPK1A, UMOD, GP2, MFRP, SHANK2, CEACAM6, PSEN1, SCNN1G, SLC7A9, CEACAM7, PARD3, SLC39A8, AMOTL2, SPTBN2, ZMYND10, DSG1, CFAP126, FLOT1, SORBS2, SLC26A2, LRP2, ANK2, DLG1, VAMP3, SLC9B2, TMEM30A, NPC1L1, VANGL2, MSN, ANXA13, ADCY8, ITPK1, MAL2, AMN, T |
| apical plasma membrane urothelial plaque | cellular component | UPK1A, UPK3A, UPK1B |
| apical tubulobulbar complex | cellular component | DNM3 |
| apicolateral plasma membrane | cellular component | CLDN6, CLDN5, MPDZ, THBD, NEDD4, KRT19, CXADR, EPPK1, PALM, KRT8, JUP, FZD6, MTCL1, CLDN7, CLDN4, CLDN8 |
| apolipoprotein B mRNA editing enzyme complex | cellular component | A1CF, APOBEC3F, APOBEC3G |
| apoptosome | cellular component | CASP9 |
| ARC complex | cellular component | DICER1 |
| Arp2/3 protein complex | cellular component | ARPC1A, ACTR3, ARPC3, ARPC5, ACTR2, ARPC4, ARPC1B, ARPC5L, ACTR3C, ACTR3B |
| aryl hydrocarbon receptor complex | cellular component | AHR, AIP |
| ASAP complex | cellular component | SAP18, SART3, ACIN1 |
| aster | cellular component | MAP9 |
| ASTRA complex | cellular component | TTI1, TTI2 |
| astral microtubule | cellular component | MAP9, FAM161A, KIF18B |
| astrocyte end-foot | cellular component | MLC1, SLC2A13, MT3, ATP1B2 |
| astrocyte projection | cellular component | APP, EZR, KCNJ10, GRM3, KCNK2, SLC1A2, PINK1, GRM2, MT3, ATP1B2 |
| asymmetric synapse | cellular component | GSG1L, ARFGEF2, DTNBP1, CHRM3, GRIA2, SNAP47, SLC4A8, CHRM1, SLC6A9, ADORA2A, CHRM2, GRM7 |
| asymmetric, glutamatergic, excitatory synapse | cellular component | NLGN4X, NLGN4Y, SHISA7, SHISA6 |
| ATF1-ATF4 transcription factor complex | cellular component | ATF1, ATF4 |
| ATF4-CREB1 transcription factor complex | cellular component | ATF4 |
| Atg1/ULK1 kinase complex | cellular component | RB1CC1, C9orf72, WDR41, ULK1, SMCR8, TBC1D5, SESN2, ATG13 |
| Atg12-Atg5-Atg16 complex | cellular component | ATG12, ATG5, WDFY3 |
| ATP-binding cassette (ABC) transporter complex | cellular component | ABCB6, ABCB8, ABCA2, ABCD4 |
| autolysosome | cellular component | MAP1LC3A, FTL, NCOA4, FTH1, PIK3C3, LAMP2, SQSTM1, LAMP1, CLN3, LRRK2 |
| autophagosome | cellular component | IL1B, MEFV, HSPA8, NBR1, OPTN, MAP1LC3A, VPS18, C9orf72, TP53INP1, ATG12, ATP13A2, PIK3C3, ZFYVE1, SNAP29, STX17, RUFY4, ATG5, ULK1, SQSTM1, ATG16L2, RAB23, PIP4K2A, SRPX, WIPI2, BECN1, TBC1D12, ATG9A, NRBF2, GABARAPL1, GABARAP, CALCOCO2, WDFY3, PIP4K2C, PIK3R4, UVRAG, GABARAPL2, GRAMD1A, OSBPL7, MAP1LC3B, CLN3, STING1, HTT, PIP4K2B, VTI1A, VPS16, TRIM21, TBC1D5, MAPK15, VPS33A, TBC1D25, TBC1D17, AMBRA1, UBQLN4, TBC1D14, HAP1, ATG9B, FYCO1, ATG16L1, TICAM1, MAP1LC3C |
| autophagosome lumen | cellular component | DAPK2 |
| autophagosome membrane | cellular component | TMEM74, MAP1LC3A, ATP6AP2, SH3GLB1, RPN2, PRKD1, ATP13A2, SNAP29, LAMP2, STX17, WDR81, ATG16L2, RAB7A, ENTPD4, ATG9A, GABARAPL1, RUBCNL, GABARAP, CALCOCO2, UVRAG, IRGM, GABARAPL2, WIPI1, MCOLN3, MAP1LC3B, STING1, TM9SF1, TECPR1, ATG9B, VMP1, ATG16L1, MAP1LC3C |
| autosome | cellular component | MAEL, SIN3B |
| axolemma | cellular component | NRG1, ANK1, EPB41L3, SLC1A2, SPTBN1, ROBO2, CNTNAP2, THY1, KCNC1, KCNC2, ADORA2A, MYO1D |
| axon | cellular component | TGFB1, TNFRSF1B, FKBP4, FMR1, CYP17A1, MAPK1, STAT1, GSK3B, CIB1, GHRL, APP, SEMA3A, PARK7, IL1RAPL1, NRG1, COMT, TUBB3, FLRT3, DICER1, NTRK1, ADCY10, KATNB1, CA2, GC, TAC1, SHTN1, HSPA8, ACADM, ROR1, PPFIA1, KCNAB1, AGBL4, PRRT2, CNTN4, LSM1, COBL, CANX, SRI, MYH10, RAB11A, DYRK1A, GRM3, PALLD, OLFM1, ARL8B, SCN11A, KIF1C, ATP6AP2, IQGAP1, PPT1, FXR1, ANK3, ALS2, DHX36, TANC2, SLC38A7, FEZ2, NPTN, ADGRL1, KCNK2, SYT13, MYH14, NIN, C9orf72, RTN4R, MAPK8IP1, NCAM2, CRYAB, NEFH, SNCA, HTR3A, GRIPAP1, DAB2IP, KIRREL3, UHMK1, INPP5F, DVL1, ANXA3, KCNA4, EPHB2, GPM6A, NEXN, TPGS1, SETX, AP3D1, PPFIA2, BCR, MAP4, SLC1A2, HCFC1, ABR, ATL1, RAB5A, CTNNA2, NTF4, GLDN, LRRTM1, ROBO4, ADNP, DISC1, TAOK2, DDC, SYT1, NEK3, BCAR1, NRN1L, MACO1, FZD3, STMN3, IGSF9, DNM3, RNF6, DTNA, SYT5, KIF1B, CALB1, GABRG2, HPCA, CNTN2, NTRK2, SARM1, SPG11, PHB2, FEZ1, N4BP3, SYN1, MX1, MAP2K4, EPHB1, DST, SCN1B, CPEB4, KLHL24, NRCAM, DTNBP1, SLC38A2, GAD1, ULK1, ITGA2, PSEN1, UCN, PRSS12, SLC8A3, STX1B, MYPN, PINK1, CHRNA10, NCDN, CNTNA |
| axon cytoplasm | cellular component | SOD1, HIF1A, KIF3B, RANGAP1, KIF5B, AGBL4, BLOC1S2, ACTR10, RAB21, TRAK2, ZC3H14, ARL8B, AP3M1, KIF1C, AP3B1, SNAPIN, AP3S2, AP3D1, AP3M2, AP3S1, AP3B2, RAB27B, OPA1, KIF1B, BLOC1S1, DST, DTNBP1, TRAK1, KIF5A, TMEM108, BLOC1S4, ARL8A, BLOC1S6, KIF4A, KIF1A, SPG7, DLG2, HAP1, TRIM46, SPAST, HSPB1, NEFL, UCHL1 |
| axon hillock | cellular component | TPX2, MAP2, PRKCZ, CCK, SERPINF1, SPTBN4 |
| axon initial segment | cellular component | ANK3, NAV1, KCNQ3, NRCAM, KCNQ2, MAP2, NFASC, SCN1A, CCK, SPTBN4, BIN1, TRIM46, SCN8A, IQCJ-SCHIP1 |
| axon terminus | cellular component | FMR1, GNRH1, FLRT3, ANXA5, ROR1, PRRT2, SRI, HNRNPR, KCNK2, TULP1, RAB5A, DGKI, NTS, NTRK2, ELK1, CRHBP, GAD1, GLUL, ITGA2, CHRM3, UCN, SLC8A3, KCNC4, GOT1, RGS10, SLC8A1, RNF40, OPRD1, NPFF, EPHA4, PDYN, ATP6V0D1, CRHR2, KCNA6, CDH8, SLC9A6, KCNA2, SLC4A8, UCN3, CHRM1, ADRA2C, KCNAB2, DRD2, NTSR1, KCNA1, KCNIP3, SYT7, SLC8A2, CHRM2, CDHR3, PACSIN1, SLC4A10, TANC1, PENK, GPER1 |
| axonal growth cone | cellular component | FKBP4, FLRT3, SHTN1, KIF5B, TRAK2, COBL, OLFM1, NIN, C9orf72, RTN4R, MAPK8IP1, GPM6A, NRXN1, TAOK2, WDR47, TRAK1, PARD3, TRPV2, MYO9A, TIAM1, CYFIP1, EPHA4, LRP1, CLASP2, L1CAM, PTCH1 |
| axonal spine | cellular component | EEA1, SLC9A6, GRIA1 |
| axonemal central apparatus | cellular component | SPAG16 |
| axonemal central pair projection | cellular component | HYDIN |
| axonemal dynein complex | cellular component | DNAH1, DNAH5, DNAH2, DNAH17, CCDC65, DNAH3, DNAI2, WDR78, DNAH8, DRC1 |
| axonemal microtubule | cellular component | TTC30A, ARFGEF2, ARL6, SAXO1, CEP162, RPGRIP1L |
| axonemal outer doublet | cellular component | CFAP73, CFAP100 |
| axoneme | cellular component | 39326, DNAH9, CCDC103, SPAG16, DYNC2H1, DNAH5, GLI3, SEPTIN2, EFHC1, CFAP70, ARMC4, CFAP91, MNS1, DNAAF1, IFT57, DNAH2, KIF17, DNAH17, SEPTIN9, CCDC65, PRKAR2A, AKAP14, TRAF3IP1, RPGRIP1, TULP3, KIF19, CFAP36, DYNC2LI1, KIFAP3, DRC3, MAP4, WDR35, DNALI1, RSPH9, RP1, PIK3C3, ARL6, CCDC63, DCDC2, CENPF, ARL13B, ATG5, DZIP1L, DCX, CFAP61, DNHD1, DNAI2, RSPH6A, DNAH10, DNAH8, CCDC114, GABARAP, LCA5L, CFAP221, WDR34, PIK3R4, CFAP46, AK8, MAP1LC3B, TUBB4A, GLI1, DRC1, GAS8, SPEF1, CCSAP, LCA5, MAPK15, GLI2, CCDC40, INPP5E, TTLL3, RP1L1, BBS1, CFAP74, AMBRA1, IFT172, RPGRIP1L, TCTEX1D2, SEPTIN7, ATG16L1, SPATA7 |
| azurophil granule | cellular component | HEXA, HEXB, SNAP23, STX3, STX7, ANXA11, OLFM4, MPO, DEFA4, AZU1, STXBP2 |
| azurophil granule lumen | cellular component | FUCA1, ACTR10, FTL, GLA, ACLY, PSMD1, DSN1, GDI2, CCT2, FAF2, PLAC8, CTSC, FABP5, GUSB, MNDA, ARHGAP45, RNASE2, PRDX6, IST1, DEFA3, GGH, PADI2, HEBP2, CTSG, PTGES2, CTSA, ARSB, NAPRT, TUBB, CCT8, TUBB4B, TOLLIP, SDCBP, C6orf120, FUCA2, GNS, SERPINB3, GALNS, PRKCD, DNAJC3, CREG1, CYB5R3, ORM2, S100A7, ACTR2, RNASE3, TXNDC5, PYGB, GRN, VAT1, MPO, BPI, DEFA1, UNC13D, PYCARD, TRAPPC1, AZU1, IMPDH1, PRSS57, PRTN3, GCA, FRK, HRNR, CPPED1, AGA, CAP1, SERPINA3, GM2A |
| azurophil granule membrane | cellular component | NDUFC2, GLIPR1, SURF4, SYNGR1, CPNE3, BST2, VAMP8, TOM1, PSAP, VAMP1, STOM, PRCP, ABCA13, SNAP29, LAMP2, CEACAM8, MANBA, CD63, CKAP4, PIGR, DDOST, CEACAM6, PSEN1, CMTM6, VAPA, MAGT1, TMEM30A, SLCO4C1, CPNE1, ATP11B, VAMP7, ARL8A, B4GALT1, DNAJC5, BRI3, ATP8A1, LAMP1, C3AR1, LAMTOR1, VNN1, TMEM179B, NFAM1, AZU1, RAB5C, LPCAT1, RAB3D, IRAG2, ATP6V0C, RAB37, RAP1B |
| B cell receptor complex | cellular component | CD79A, CD79B, SYK, LIME1 |
| Barr body | cellular component | MACROH2A2, H2AZ1, MACROH2A1, SMCHD1, LRIF1, H3-3A |
| basal cortex | cellular component | PKD2, PHLDB1, PHLDB2, CLASP2, CLASP1 |
| basal dendrite | cellular component | SH3GL2, MAP2, YKT6, MAP1B, SLC4A10 |
| basal lamina | cellular component | FN1 |
| basal part of cell | cellular component | TF, HFE, ITGA6, CLDN11, ADCY10, PRCP, ITGA2, DOCK7, EDN1, KRT14 |
| basal plasma membrane | cellular component | TF, ITGA6, BMPR2, AQP5, ERBIN, SLC12A2, ANK3, SLC1A5, CD34, EPS15, SLC27A5, OSCP1, SLC1A3, TEK, PKD2, SLC27A1, DST, P2RY12, CHRM3, TACSTD2, SLC7A1, ERBB3, AQP1, C5AR2, SLC23A1, CEACAM1, ITGA9, SLC5A6, SLC16A1, MST1R, DAG1, MYO1C, KCNQ4, CLDN4, MUC20, SLC23A2 |
| basal tubulobulbar complex | cellular component | DNM3 |
| basement membrane | cellular component | TIMP1, ALB, ITGB1, ADAMTS1, ITGA6, FN1, ANXA2, FGF9, ERBIN, LAMC1, PTN, FBN1, LOXL2, COL4A1, COL8A1, TIMP3, RELL2, MATN2, COL7A1, USH2A, COL2A1, LAMA4, NTN1, COL4A2, LAMC2, FREM2, ACAN, FBLN1, CD151, EFNA5, DST, NTN4, COL4A6, FREM3, COL4A3, FRAS1, DLG1, MEGF9, TNC, TGFBI, TINAG, HSPG2, VWA2, VTN, LAMB1, COL8A2, TMEFF1, CASK, COL5A1, NID2, EGFLAM, SMOC2, COL18A1, LAMB3, DAG1, LAMC3, THBS4, COL15A1, LAMA3, TMEFF2, LAMA5, ANG, SERPINF1, VWC2, NTN5, COL17A1, AGRN, NTN3, EFEMP2, THBS2, COL4A4, VWA1, COL28A1, SMOC1, FREM1, ENTPD2, APLP1 |
| basolateral plasma membrane | cellular component | EGFR, IL6R, ERBB2, HSP90AA1, CFTR, ABCC1, CTNNB1, LEPR, CD46, LPO, ITGA6, EZR, ANXA2, ANK1, PKD1, DDR1, CA2, SLC19A1, ATP6V1B1, AQP2, P2RY4, KCNJ10, ERBIN, CD38, MLC1, CNNM2, TJP1, MAP4K2, ANK3, VSIG1, KCNJ16, EPCAM, SLC14A1, SLCO1B3, PDGFB, TGFA, NUMB, CD81, PTH1R, LIN7C, SLC41A1, RHBG, NDRG4, SLC4A7, TFRC, ANXA1, SLC22A9, SLC7A6, LIN7A, AQP9, LDLR, IDE, CTNNA2, CD300LG, ALPK2, LRRC1, SLC12A6, SLC9A1, CA9, GPIHBP1, NOD2, SLC4A4, HPGD, ATP7B, TEK, NAIP, PKD2, SLC7A8, UMOD, ENPP1, SLC26A5, SCRIB, CNNM4, SLC39A5, SLC26A7, OTOF, ADRA2A, CHRM3, SLC39A8, DSP, SLC22A7, FLOT1, ANK2, CDH17, DLG1, SLC29A2, SLC9B2, HEPH, VANGL2, MSN, ANXA13, ADCY8, SLCO4C1, SLC16A10, AQP3, WASF2, CXADR, ADAM9, B4GALT1, EPPK1, ATP7A, DSTYK, STXBP3, SLC7A1, SLC4A2, KCNJ4, SLC4A11, SLC40A1, ATP1B1, ERBB3, AQP1, P2RY1, LRP1, PDPN, DLG3, TLR9, SLC7A7, CASK, PALM, CALHM1, SLC5A6, PLPP3, CA11, ATP1A1, TSHR, ATP2B1, SLC16A1, STX4, DAG1, TRPC4, CDH16, CLDN1, SLC51B, KCNC2, RAB17, ABCC5, CLDN7, SLC16A12, NKD2, SLC29A1, SLC26A1, RHCG, NOD1, ABCC6 |
| BAT3 complex | cellular component | BAG6, GET4, UBL4A |
| BAX complex | cellular component | BAX |
| BBSome | cellular component | BBS2, BBS5, BBS9, TTC8, BBS4, BBIP1, BBS1 |
| Bcl-2 family protein complex | cellular component | BAX, MCL1, BCL2L11, BCL2L1 |
| Bcl3-Bcl10 complex | cellular component | BCL3 |
| Bcl3/NF-kappaB2 complex | cellular component | BCL3, NFKB2 |
| BCOR complex | cellular component | BCOR |
| beta-catenin destruction complex | cellular component | GSK3B, CTNNB1, SIAH1, CSNK1A1, CTNNBIP1, AXIN1, CACYBP, APC, DACT1, AXIN2, APC2 |
| beta-catenin-TCF complex | cellular component | CTNNB1, TLE1, BCL9, TLE4, BCL9L, TCF4, LEF1, LDB1, TLE3 |
| beta-catenin-TCF7L2 complex | cellular component | CTNNB1, TCF7L2, TCF4 |
| bicellular tight junction | cellular component | CTNNB1, NPHP1, CLDN11, NPHP4, CLDN14, CLDN6, CLDN2, WNK3, YBX3, RAP2B, TJP1, ANK3, CYTH3, EPCAM, MARVELD3, WNK4, RAPGEF2, CLDN9, VASP, CLDN15, CLDN12, PMP22, BVES, LIN7C, CLDN5, MPDZ, JAM3, LIN7A, MPP7, SYNPO, CLMP, CCND1, AMOT, PARD3B, CLDN16, CLDN18, CGNL1, TJAP1, ARHGAP17, USP53, POF1B, PARD3, CLDN23, VAPA, AMOTL2, FRMD4B, STRN, APC, DLG1, ECT2, AOC1, CXADR, ARHGEF2, MAGI1, FRMD4A, F11R, TGFBR1, CLDN17, EPPK1, PRKCZ, EPB41L4B, PARD6A, NHS, PDCD6IP, TRAF4, PARD6B, ASH1L, CLDN10, ESAM, DLG3, CYTH2, TBCD, C1QTNF5, CDH5, FZD5, PLXDC1, JAML, CLDN1, ADCYAP1R1, JAM2, CGN, CCDC85C, CLDN7, MAGI3, MAPK15, CLDN4, TJP3, SHROOM2, UBN1, SH3BP1, MICALL2, SYMPK, CRB3, PARD6G, CYTH1, FRMPD2, AMOTL1, RPGRIP1L, SAPCD2, MAGI2, LIN7B, CLDN8, MXRA8 |
| BIM-BCL-2 complex | cellular component | BCL2L11 |
| BIM-BCL-xl complex | cellular component | BCL2L11 |
| bleb | cellular component | TPM1, PANX1, ANLN, ROCK1, PTPRC, P2RX7, FHOD1, FMNL1 |
| BLOC-1 complex | cellular component | BLOC1S2, STX12, KXD1, SNAPIN, WASHC4, BLOC1S1, DTNBP1, SNAP25, BLOC1S4, SNAP47, PI4K2A, BLOC1S6, BCAS4 |
| BLOC-2 complex | cellular component | HPS3, HPS5 |
| BLOC-3 complex | cellular component | HPS4, HPS1 |
| blood microparticle | cellular component | SERPINC1, TGFB1, APOE, PON1, C3, ALB, TF, KRT1, CLU, AFM, HSPA2, A2M, FN1, HSPA1A, HSPA1B, HSPA1L, ACTB, LGALS3BP, OAZ3, SERPINA3, GC, C1QB, HSPA8, EIF2A, ITGA2B, ITIH2, CFHR1, GRIPAP1, PSMC5, ORM1, TFRC, HBG2, FGG, CFH, C1S, ZNF177, PROS1, STOM, KDM4D, SERPINF2, YWHAZ, ACTC1, FCN3, CFB, HBD, FGB, C1QC, HBB, BCHE, APOA1, CFHR3, SDCBP, MSN, ZBTB38, DNPEP, CIB2, ACTG1, ORM2, CLIC1, ANGPTL4, HPR, VTN, HP, PLG, C1R, FGA, HSPA6, INTS11, APCS, HRG, SERPING1, HBA1, ITIH4, F2, AMBP, POTEF, SLC4A1, ACSM1, TMPRSS13, AGT, AHSG, C8G, CPN2, APOL1 |
| BMP receptor complex | cellular component | ACVR1, HJV, BMP2, ACVRL1 |
| BORC complex | cellular component | BLOC1S2, KXD1, SNAPIN, BORCS5, BLOC1S1, BORCS7, BORCS8 |
| box C/D snoRNP complex | cellular component | NOP58, SNU13, NOP56, FBL |
| box H/ACA scaRNP complex | cellular component | DKC1, NOP10, NHP2, GAR1 |
| box H/ACA snoRNP complex | cellular component | DKC1, NOP10, NHP2, GAR1 |
| box H/ACA telomerase RNP complex | cellular component | DKC1, NOP10, NHP2, GAR1 |
| brahma complex | cellular component | ARID1B, SMARCB1, ARID1A |
| BRCA1-A complex | cellular component | BRCA1, UIMC1, BABAM1, BABAM2, ABRAXAS1, BARD1 |
| BRCA1-BARD1 complex | cellular component | BRCA1, BARD1 |
| BRCA2-MAGE-D1 complex | cellular component | BRCA2 |
| BRISC complex | cellular component | ABRAXAS2, BABAM1, BABAM2, SHMT2 |
| brush border | cellular component | EZR, DNM1L, DCXR, MYH10, ACTR3, MYL6, SCIN, MYH14, MYL12B, SI, PLEC, GIPC1, FLNB, PLS1, SNX5, USH1C, ITPR3, SLC38A2, LIMA1, PDZD3, TMPRSS15, ESPN, LRP2, EPS8, ACTN1, ADD3, MYO1B, CAPZA2, VCL, CLIC1, FLII, ATP6V0A4, AQP1, MME, RGS19, ENPEP, SLC34A3, MYO1C, MYH9, LCTL, RALGDS, MYO7B, CDHR2, ACTN4, SLC34A1, CUBN, MYO1D, VIL1, SLC15A1, FOLR1 |
| brush border membrane | cellular component | HSP90AA1, SLC6A14, SLC22A5, SLC19A1, SLC26A4, PEX19, SLC26A3, SLC28A2, SLC28A1, SLC17A3, PTH1R, SLC9A3R1, SLC22A12, PEMT, SLC3A1, MFSD10, LIMA1, SHANK2, SLC7A9, LRP2, GNA12, NPC1L1, AMN, B4GALT1, ATP7A, ATP6V0A4, AQP1, ITLN1, KCNK1, SLC5A1, CDHR5, SLC5A6, SLC34A3, SLC27A4, ATP8B1, SLC6A19, SLC6A18, CDHR2, CA4, SLC34A1, SLC26A6, CUBN, PLB1, TRPM6, SLC28A3, CYBRD1, ABCG2, FOLR1, CD36 |
| bub1-bub3 complex | cellular component | BUB3 |
| C zone | cellular component | MYBPC3 |
| CA3 pyramidal cell dendrite | cellular component | TNN, MAP2, SLC4A10 |
| CAAX-protein geranylgeranyltransferase complex | cellular component | FNTA, PGGT1B |
| CAF-1 complex | cellular component | RBBP4, CHAF1A |
| Cajal body | cellular component | FMR1, DKC1, COIL, SHQ1, ZC3H8, NOP58, DDX46, NPAT, FRG1, SRRM2, ARIH1, XPO1, ICE2, ISG20, AK6, OIP5, HNRNPA2B1, ELL, FAM118B, NOP10, SNRPC, SART3, ZNF473, PRPF31, TOE1, NHP2, ANGEL2, WRAP53, RDM1, GEMIN4, PRPF3, ICE1, ZPR1, FBL, USPL1, TGS1, SMN1, LSG1, HABP4, HMBOX1, U2AF1, EFTUD2, DDX42, SMNDC1, HINFP, SART1, PRPF4, ANKS1B, EAF1, TRIM22, GAR1, HSPB7 |
| CAK-ERCC2 complex | cellular component | CDK7, CCNH, MNAT1 |
| calcineurin complex | cellular component | PPP3CB, PPP3CC, PPP3CA, ITPR1, PPP3R1 |
| calcium ion-transporting ATPase complex | cellular component | ATP2A2, PLN |
| calcium- and calmodulin-dependent protein kinase complex | cellular component | CAMK2B, CAMK2D, CAMK2G, CAMK2A |
| calyx of Held | cellular component | KCNK2, TPRG1L, CPLX1, CALB1, GIT1, PRKCB, UNC13C, UNC13B, NCS1, ACTG1, GLRA1, HTR1B, KCNA2, KCNC1, PRKCG, KCNA3, KCNA1, UNC13A, ITSN1, CPLX2 |
| cAMP-dependent protein kinase complex | cellular component | AKAP4, PRKAR2A, AKAP14, PRKACB, PRKX, PRKAR2B, PRKAR1B |
| cardiac myofibril | cellular component | DES, CRYAB, MYBPC3, MYL2 |
| catalytic complex | cellular component | P3H3, GRHPR, UXS1, CALM1, CALM2, CALM3, P3H4, QPRT, NEU2 |
| catalytic step 1 spliceosome | cellular component | XAB2 |
| catalytic step 2 spliceosome | cellular component | SNRPN, PABPC1, XAB2, RBMX2, RBMX, HNRNPF, HNRNPU, CWC27, PPIL3, PLRG1, HNRNPM, LSM3, CWC15, HNRNPR, SF3B1, HNRNPA1, HNRNPA3, RBM22, PRPF19, HNRNPC, MTREX, FRG1, SNRNP40, SRRM2, SYNCRIP, CDC40, SNRPB2, DDX23, SLU7, HNRNPA2B1, PRPF6, SYF2, SNRPE, SF3B2, RBM8A, SNRPB, DDX41, ALYREF, AQR, SNRPD1, SNRPD2, PNN, BCAS2, HNRNPH1, SNRPG, PRPF8, MAGOHB, SNRPA1, PRPF4B, SNW1, ZCCHC8, SF3A1, PPWD1, ISY1, SNRNP200, SF3B3, U2AF1, EFTUD2, PPIE, SF3A3, SNRPF, SRRM1, LSM7, LSM2, ESS2, HNRNPK, WDR83, TFIP11, RALY, SART1, EIF4A3, SF3A2, CACTIN, GPATCH1, DHX35, CDC5L, CRNKL1 |
| catenin complex | cellular component | CTNNB1, CDH1, CDH7, CTNNA1, DCHS1, CDH10, CTNND1, CDH19, CDH12, APC, CDH17, CDH6, CDH9, CDH5, CDH8, CDH11, CDH13, JUP, APC2, CDH3, CDH4, CDH15, CDH24, CDH23, CDHR3, CDH26, CDH22 |
| catenin-TCF7L2 complex | cellular component | CTNNB1 |
| cation channel complex | cellular component | TRPC3, PKD2, PKD2L1, TRPC7, UNC80, TRPC1, TRPC5, TRPC4 |
| cation-transporting ATPase complex | cellular component | SLC9A1 |
| CatSper complex | cellular component | CATSPER1, CATSPER2, HSPA2, CATSPER4, CATSPER3, CATSPERB, CATSPERG, CATSPERD |
| caveola | cellular component | NOS3, PTGS2, HMOX1, MAPK3, MAPK1, FASLG, INSR, SRC, BMPR2, F2R, LIPE, JAK2, MLC1, TFPI, PLPP2, BVES, NOS1AP, DLC1, FXYD1, BMPR1A, SPRED1, RANGRF, PLPP1, SCARB1, EMP2, IRS1, EFNA5, CAV3, P2RY12, PACSIN2, LRP6, ADRA1A, CAV2, SMO, ADTRP, FLOT1, ATP1A2, ADCY8, PTGIS, KIF18A, CAVIN3, CLN3, HDAC6, SMPD2, ATP1B1, MYOF, EHD2, TGFBR2, CDH13, ATP1A1, HCK, TRPC4, ADRA1B, ADCYAP1R1, ATP1B3, CDH15, PTCH1, CAVIN1, SCN5A, PLVAP, KCNMA1, ASAH2, CAVIN2, CAV1, AKAP6 |
| caveola neck | cellular component | LRRK2 |
| caveolar macromolecular signaling complex | cellular component | CAV2, CAV1 |
| CBM complex | cellular component | MALT1, BCL10, CARD10, CARD11 |
| CCAAT-binding factor complex | cellular component | ING2, NFYC, NFYA, NFYB |
| CCR4-NOT complex | cellular component | CNOT1, CNOT4, CNOT8, CNOT10, PATL1, CNOT9, TOB1, CPEB3, CNOT6L, CNOT2, ZFP36, CNOT3, TNKS1BP1 |
| CCR4-NOT core complex | cellular component | CNOT1, CNOT8, CNOT9, CNOT2, CNOT3 |
| CD40 receptor complex | cellular component | HTRA2, TRAF3, BIRC2, TRAF6, DIABLO, IKBKB, TRAF5, RNF31, CD40, TRAF2 |
| CD95 death-inducing signaling complex | cellular component | FAS, CASP8, FADD, CFLAR, FAF1, CASP10 |
| Cdc73/Paf1 complex | cellular component | PEX2, WDR61, PAF1, RTF1, CTR9, CDC73, SETD5, LEO1 |
| cell | cellular component | MEI1, PROK2, MAPK14, C1QB, OLFM1, RAMP2, LDLR, NPY, P2RY12, C1QC, TTL, VPS35L, TYROBP, FAM20A, VCL, TGFBR1, RAMP3, DENND10, C1QA, RAMP1, CRCP, TLR6, CXorf21, CD36 |
| cell body | cellular component | IL6ST, GSK3B, CASP8, GNAO1, PARK7, NRG1, APOA1BP, EZR, COMT, HSPA1L, NF2, PACRG, CCT5, CCT4, RPS6, KCNJ10, CCT7, ATP6AP2, SLC12A2, GNAI2, GNB3, CCT2, MAPK8IP1, STAU1, TCP1, RACK1, DPYSL3, SLC1A2, GNB1, PITPNM3, PGRMC1, GNAZ, CCT3, DISC1, FCGR2B, CALB1, ACTC1, FADD, RIT2, GABRA5, GLUL, USP33, PINK1, CXorf56, TRPV2, TUBB, CD3E, RPL28, CCT8, PTPN13, SLC2A13, CACYBP, MAP2, CXADR, ZPBP2, RNF157, GABARAPL1, GABARAP, GNG3, PITPNM1, EPHA4, CACNG4, HDAC6, FABP7, P2RY1, TMEM132E, GNB2, PITPNM2, RLBP1, RDH5, P2RX4, SYNDIG1, LZTS1, EPO, PTK2B, RPE65, ACTA2 |
| cell body fiber | cellular component | SRD5A2, SRD5A1, ASS1, SACS, SPTBN4, PENK |
| cell body membrane | cellular component | SLC12A2, P2RY12, ATP1B2 |
| cell cortex | cellular component | FGFR2, CTNNB1, NSMF, EZR, ANXA2, CCN2, SEPTIN2, NRBP1, COBL, ASTN2, MYH10, GPSM2, AKAP12, FERMT2, FNBP1, SCIN, ARHGAP32, PXN, GYS2, ARHGEF7, RHOU, SPINK5, PLA2G4C, SNCA, C2CD5, CORO1C, GIPC1, FLNB, PTK2, FNBP1L, HAX1, RYR1, GRK4, TSC1, CNKSR1, CTTN, GPSM1, RHOG, PDZD4, PARD3B, CTTNBP2, ANLN, RIC8B, GLRX3, LAMC2, FRMPD1, NEDD4, DST, GAD1, DBNL, TRAK1, FGB, PSEN1, MELK, STOX1, MICAL3, PARD3, MYO6, SPTBN2, NEDD9, FRY, RHOQ, EPS8, RHOBTB3, CLIP1, RAC1, SPIRE1, CLIP4, ECT2, ADD3, RAC2, FER, NUMA1, NDFIP1, TRAF6, PRKCZ, AKAP13, PARD6A, CLIC5, ACTR2, ACTR1A, TBCB, PARD6B, MYO10, CABP1, BIN2, DCTN4, CYTIP, SPTB, SPTAN1, TRIP10, ARF6, ITPR2, AGTRAP, KDF1, CLASP2, NCL, RAC3, FGA, PSEN2, LASP1, RHOJ, RAI14, MARCKS, CORO1A, MYH9, RHOV, MISP, AKT2, MYO7A, MYO9B, POTEF, HIP1R, TRAF2, FSCN1, KIAA1614, CLASP1, RASAL3, SPIRE2, PARD6G, SPTBN4, CLIP2, MYO1D, FGF1, EPB41, BFSP2, KCNC3, PTK2B, GRM7, FMN2, FMNL1, FAM110C, SAPCD2, CLIP3, EPB41L2, FRYL, CAV1 |
| cell cortex region | cellular component | ACTR10, GPSM2, MYL12B, ANLN, NUMA1, ACTR1A, CTSZ, ACTR1B, EPB41, EPB41L2 |
| cell division site | cellular component | SEPTIN2, SEPTIN9, SEPTIN10, SEPTIN11, SEPTIN1, SEPTIN5, SEPTIN8, TMEM250, SEPTIN14, SEPTIN3, SEPTIN7 |
| cell junction | cellular component | NRIP1, KDR, ITGB1, CTNNB1, PLAUR, NSMF, NPHP1, CLDN11, CDH1, GJA1, RAP1A, PICK1, FLRT3, DNM1L, SYNM, NPHP4, DSCAML1, LRRC4C, PTPRJ, GOPC, PJA2, CLDN14, GABRB1, CLDN6, CLDN2, CAMK2B, GJC2, PRRT2, SHROOM3, COPS5, ERBIN, SORBS1, LPXN, CHRNA5, GTF2A2, CXCR4, ZNRF2, PALLD, FERMT2, OLFM1, ARL8B, RIMS2, NOX1, ATP6AP2, TJP1, ANK3, RAPSN, FAT1, PTPRR, TNS3, NUDT9, MFF, MRPL46, TANC2, RTN4, GJD2, NPTN, ATP23, SCIN, ARHGAP32, SNAP23, RAD51C, CYTH3, SYNGR1, CPNE3, ADGRL1, SVIL, DMD, EPCAM, GABRA2, PXN, CHRNE, GRIN1, PTK7, ARHGEF7, TNS2, RHOU, NLRX1, TNS4, NLGN4X, BAALC, MARVELD3, WNK4, PPP1R9B, PEAK1, DCAF13, FLRT1, RGS17, RAPGEF2, CLDN9, LGI1, IFI30, RPS6KB1, CTNNA1, GTF2F1, SNCA, HTR3A, VASP, CLDN15, CLDN12, TP53BP2, PLEC, GRIPAP1, RIMS1, BVES, DLG5, PANX3, TM9SF2, SH3GL2, LIN7C, PSD3, JCAD, CORO1C, CACNG2, CLDN5, WDR1, MPDZ, NEURL1, FCHSD2, SNAPIN, PTPRA, UTRN, GPM6A, FABP5, PTK2, NEXN, TPRG1L, SPECC1L, GSG1L, DCP2, ZDHHC17, SMC5, AHI1, PAF1, DDB2, DLC1, CDK5RAP2, COPS4, JAM3, TRIM9, SEMA4C, MIOS, EPB41L3, ARFGEF2, TU |
| cell leading edge | cellular component | VIM, SHTN1, CORO1B, DDX3X, CXCR4, ARPC3, IQGAP1, JMY, CCDC88A, ARF1, CAPRIN1, BSPRY, DST, SCRIB, RAPH1, EPB41L5, SRA1, ITGB4, AAK1, PHLDB2, TUBG1, DOCK8, ABL1, ABI1, SLK, SSX2IP, ATP7A, PRKCZ, CARMIL1, EXOC8, BCAS3, CD2AP, DUOXA2, LDB1, DUOX2, HDAC6, KDF1, CDC42BPB, CLASP2, SSH1, DUOXA1, GBF1, LDB2, CORO1A, MYH9, CDC42BPG, CARMIL2, DUOX1, SH3BP1, DPP9, RIPOR1 |
| cell periphery | cellular component | CIB1, CTNNB1, FUT4, EZR, CDC42, TUBB3, CORO1B, THSD1, SLC12A2, MINDY1, CLDN12, SLC9A3R1, CD34, ARHGEF5, NOTCH1, CHRNA2, KRT18, SLC1A3, PHB2, EFNA5, ODAM, AXIN1, PTPRC, AGAP3, SLC2A13, LYVE1, ITGB1BP1, PDE4B, SLITRK6, VANGL2, MBP, MSN, MINDY2, MYO1B, KRT19, SLC8A1, MAGI1, STK26, RDX, EPPK1, NME2, KRT17, BCAS3, PPP5C, DLG4, PRKCE, SLC24A3, FABP7, CDH5, RAC3, SLC12A5, SMOC2, KRT8, ATP1B2, PECAM1, SNORC, NKD2, KRT14, ITGA3, ADGRE1, CD36, GAP43, PANK1 |
| cell pole | cellular component | ASTN2, VANGL2 |
| cell projection | cellular component | GNAS, FKBP4, FMR1, STRC, CATSPER1, CATSPER2, NDRG2, BGLAP, CYP17A1, KANK1, CIB1, ITGB1, VIM, PTEN, PLAUR, ODF2, AKAP4, NSMF, IL1RAPL1, NPHP1, MEFV, CABYR, EZR, MAK, CDC42, 39326, 41153, SPRY4, DNAH9, FLRT3, NPHP4, NF2, AIF1, PKD1, DNAH12, CATSPER4, CATSPER3, CCDC103, SPAG16, DYNC2H1, TEKT4, ADCY10, TEKT3, DNAH1, TEKT2, MYO15A, KIF3A, 38231, ANXA5, AGFG1, CX3CL1, PTPRJ, DNAH5, DNAH11, GOPC, DNAI1, SHTN1, CFAP69, PSTPIP1, OFD1, GLI3, CCT4, ROR1, PDE4C, IFT88, SEPTIN2, PCM1, CFAP70, ARMC4, AGBL2, AGBL4, CFAP65, RAB11FIP2, CFAP91, PRRT2, RSPH3, LRRC6, DZIP1, NRSN1, DNAAF1, WDR19, PMFBP1, ELMOD3, TXNDC15, MEGF10, CEP20, TTC25, DNAH6, QRICH2, ANTXR1, IFT22, IFT57, DNAH2, KIF17, DNAH17, NRBP1, RAB21, MOK, DDX3X, LPXN, COBL, SLC2A3, MYH10, CSNK1A1, ACTR3, MAX, MTM1, MTSS2, NEK8, CCDC65, DAW1, ZNRF2, PALLD, FERMT2, IFT74, CEP19, NDN, OLFM1, BBS2, FHDC1, ARL8B, PLK2, RIMS2, BAIAP2, NOX1, ARPC3, OGT, CCP110, ATP6AP2, MARK3, RCVRN, SLC12A2, MLF1, TJP1, ANK3, TTC30A, TMEM17, TRAF3IP1, TCTN2, RPGRIP1, CFAP53, ZNF385A, RAB3 |
| cell projection membrane | cellular component | CTNNB1, SLC12A2, BVES, KIRREL1, NDRG4, RAB35, P2RY12, FSCN3, DLG1, MAPRE1, ATP1B2, DMTN, FSCN1, ASAP1 |
| cell surface | cellular component | EGFR, TGFB1, TNF, HLA-DRB1, HLA-DPB1, ICAM1, IL6R, TGFB3, VEGFA, CD44, TNFRSF1A, FAS, STRC, HLA-B, HLA-A, HSP90AA1, ABCB1, CFTR, HLA-E, FGFR2, FGFR3, AXL, FASLG, TLR4, TLR2, HLA-DRA, TF, APP, ITGB1, ITGA5, CLU, F3, PRLR, HSPA2, TGFBR3, IL1RAPL1, IL2RA, LTF, ITGAV, KIT, HSPA5, IGF2R, ITGA4, MIF, CD46, FUT4, ITGA6, PDIA3, DPP6, C1QBP, BMPR2, GPRC6A, KISS1R, EPPIN, PLAU, PLAT, MMP7, HSPD1, NCAM1, CD9, F2R, CCR5, BSPH1, SHH, DEFB106A, DEFB126, DEFB129, NTRK1, ANXA2, ELANE, PKD1, DSCAML1, CD8A, MAS1, ANXA4, HLA-C, TIMP2, CX3CL1, PTPRJ, ACE2, PRNP, ALPP, AREG, PAM, HNRNPU, ROR1, LRFN4, ISLR2, GPC2, SEMA6D, LRFN5, ANTXR1, CLDND1, SIRPB1, ATP5F1B, CPM, CD38, IL15, CXCR4, ASIC1, NDP, FERMT2, TNN, FZD9, CD74, CD55, SLC6A2, USP14, ANK3, IQGAP2, NPTN, TNFRSF10C, KCNK2, LPL, TFPI, DMD, TDGF1, EPCAM, ATP5PF, VCAM1, ACVR1B, GRIN1, CD47, BST2, NLGN4X, ADGRA2, RTN4R, FZD4, LILRA5, HTR3B, PDGFB, TGFA, CRYAB, ITGA2B, RALA, IL1R1, ITGB5, PTN, TREML1, DCBLD2, CD93, CACNG2, HMMR, LYZL6, CD58, BCAM, GPC5, KCNH2, CD226, ANO6, AQP11, |
| cell tip | cellular component | EZR, RAB8B, RDX, SLC32A1 |
| cell-cell adherens junction | cellular component | CTNNB1, CDH1, OXTR |
| cell-cell contact zone | cellular component | PCDH9, RAP2B, JAM3, SCRIB, PKP4, AHNAK, FLOT1, TIAM1, VCL, FLCN, NECTIN1, PECAM1, JAM2, AJAP1, BAIAP2L2, AFDN, OPALIN |
| cell-cell junction | cellular component | AKT1, APP, ITGB1, ITGA5, CTNNB1, KIT, NPHP1, GJA1, CDC42, TWF1, FLRT3, NPHP4, AQP7, PTPRJ, CLDN2, DES, ACTR3, MLC1, IQGAP1, FAT1, PIK3R1, PXN, PTK7, FLRT1, FZD4, PIKFYVE, RAPGEF2, NCK1, CTNNA1, KIRREL1, CNN2, LIN7C, JCAD, CLDN5, WDR1, STX3, IQGAP3, AHI1, JAM3, EPB41L3, CTNND1, CNKSR1, ARVCF, LIN7A, CD53, PTPN6, AJUBA, LRRC1, CLIC4, PCDHGA12, ITK, FRMD1, FLRT2, HPN, ZAP70, TEK, PKD2, GJB3, SCRIB, USP53, SDCCAG8, PKP4, TMEM47, PACSIN2, SKAP1, PARD3, CD3E, DSP, DSG1, FLOT1, ITGB3, MAP2K2, DLG1, TIAM1, PNN, TENM2, VANGL2, ACTN1, PTPRM, GRB2, GAB1, AQP3, ECT2, ADD3, CTNND2, WASF2, KRIT1, PDZD2, ACTG1, CXADR, MAGI1, F11R, WTIP, VCL, PRKCZ, PRKCD, FRS2, PTPRU, MYADM, CD2AP, CD2, LCP2, DSC3, ESAM, P2RX7, PKP2, FABP7, ILK, DSG2, NECTIN1, DLG3, CDC42BPB, ADGRB1, CASK, CEACAM1, SLC5A1, CDH5, DSC2, LIMD1, KRT8, JUP, WAS, PCDH1, DAG1, PCDH12, TRPC4, LAT, CLDN1, NGFR, PECAM1, CORO1A, DSG3, VAV1, FGFR4, CSK, COL16A1, COL19A1, MAGI3, CADM3, MAPK15, COL17A1, PKP3, CLDN4, PLEKHG5, TJP3, PRKCG, LIMS2, PDXP, ACTN4, RHO, SGCA, FS |
| cell-substrate junction | cellular component | SORBS1, FERMT2, DMD, FERMT1, PGM5, VCL, TNS1, FERMT3 |
| cellular_component | cellular component | DMRT2, TSPY1, INSL6, KDM5D, SLC6A8, DNAH5, SPATA25, DENR, PLCH2, PRPS1L1, LHFPL2, TMEM116, RIN2, DOHH, MKRN1, CHORDC1, TRIM17, MFSD11, LIPF, NME5, RALGPS1, TTC27, CCDC65, DAW1, SCFD2, PHF3, TMEM106C, CISH, ASNSD1, TNN, OSGIN2, LRRFIP2, DISP2, FAU, CRYBA4, ATP5MPL, IFI44L, CWF19L1, DLEU7, CELF5, CFAP53, CDK5RAP1, SMCO4, ZFAND5, PGM3, CRYGA, PLAAT3, AUTS2, FGGY, TMEM101, STOX2, TMSB15B, RCAN2, LRRC34, KIAA1191, SEPHS2, GGTLC1, BTG4, C21orf62, OGFR, ZNF324, RWDD2B, C19orf57, ADNP2, AMZ2, SLC22A15, SH3TC1, USP29, ETNK2, SIPA1L2, DLGAP1, TRAF3IP2, QRFP, LTB, ASCL4, TC2N, SMG8, TMEM120A, VSX1, ARPP21, ODC1, MAGEA6, SMIM11A, C9orf64, ZDHHC23, LENG1, DCUN1D5, CHCHD7, VPS45, ZNF107, SBNO2, SBNO1, CDRT1, NKX2-3, MOCOS, CDHR1, C22orf23, RNASEL, TMEM128, ANKRD40, LIX1L, SNRNP27, TRIT1, KCND1, STOML1, CCDC130, CSHL1, TSTD2, USP53, GALNT5, GSDMB, NLRP7, AIDA, ZFP3, NKIRAS1, KAAG1, SHANK2, ZXDC, POGLUT3, CEP57L1, TMEM132C, SUSD6, RGL1, CCDC182, ZNF688, MAGEA12, TSNAXIP1, BCL7A, SPATA3, PCYT2, RETNLB, NKIRAS2, SMAP, BMP5, MA |
| central element | cellular component | TEX11, SYCE1, SYCP1, SYCE3, SIX6OS1, INCENP, TEX12 |
| central region of growth cone | cellular component | DISC1, YWHAE, CYFIP1 |
| centralspindlin complex | cellular component | ECT2, KIF23 |
| centriolar satellite | cellular component | OFD1, KIF5B, PCM1, DZIP1, CEP20, CCDC113, NUDT21, RAB11A, KEAP1, CCDC14, DLGAP5, CEP55, NEK1, RAB11FIP5, RASSF7, C2CD5, TAP1, BBS9, KLHL12, HOOK3, CEP131, CCDC66, TMEM63A, KIAA0753, RPP25, KRT18, TEK, PRKCQ, RBM39, PIBF1, BBS4, DCDC2, ALDOB, PTPN20, SDCCAG8, DDHD2, WDR13, LATS2, TACC3, WDR62, ZMYND10, PLK1, PXK, ITGB1BP1, FLOT1, C2CD3, CEP97, MAP11, DDAH2, CENPU, IFT43, FNIP2, HAUS6, UPF3B, SSX2IP, LRIF1, KLHL4, PARD6A, KNSTRN, CEP290, CCDC13, YTHDF2, FLII, SASS6, PODXL, CEP68, TAF1D, PCNT, KCTD1, MPP1, EXOC7, DYSF, CHD3, HARBI1, NEK6, DBH, CDC42BPG, PIK3R5, RAB11FIP3, IL4R, ZNF365, CEP72, GSDMC |
| centriolar subdistal appendage | cellular component | KIF2A, CEP170, NIN, CEP128, CNTRL, CCDC68 |
| centriole | cellular component | BIRC5, ODF2, HSPA1A, HSPA1B, TOP2A, STARD9, OFD1, IFT88, PCM1, AGBL2, AGBL4, DZIP1, CEP20, BCCIP, KIF2A, CETN2, CEP19, PLK2, CCP110, DEUP1, CEP55, NEDD1, IFT52, NUBP1, CEP170, KIF24, CEP350, NIN, CEP41, CETN1, AHI1, NEURL4, CIBAR2, WRAP73, CCDC88A, WDR90, CEP43, KIAA0753, CEP120, POC5, C10orf90, PLA2G3, FTCD, SIRT2, BBS4, ROCK1, SDCCAG8, RTTN, MPHOSPH9, CBY1, PARP3, FAM92A, TTBK2, DZIP1L, CEP89, TSKS, WDR62, PLK1, SAXO1, TUBGCP3, SCLT1, CETN3, RAN, C2CD3, GLE1, CEP162, CEP164, TUBG1, CCDC92, CCDC146, ALMS1, CEP63, KIAA0586, HYLS1, CEP295, NUBP2, CEP128, MDM1, POC1B, WDR34, CEP290, ACTR1A, CCHCR1, CAPG, SASS6, TEDC1, CCNF, HTT, CEP250, SFI1, PCNT, STIL, CFAP20, HSPA6, TEDC2, AKNA, SPICE1, CNTROB, RAB8A, ARMC9, CCDC68, CCSAP, MAPK15, CCDC78, CEP104, HERC2, CROCC, FBF1, IQCB1, RILPL1, CEP192, TOPORS, RP2, HAP1, LRRCC1, RABL2B, CEP83 |
| centrosomal corona | cellular component | CLASP1 |
| centrosome | cellular component | BRCA2, NDRG2, CCNB2, CDK1, CCNB1, GSK3B, NFE2L2, CIB1, CTNNB1, GNAI1, ODF2, BRSK2, G6PD, PCNA, MAK, APEX1, CDC20, KIF3B, NPHP4, KATNB1, KIF3A, DYNLL1, DYNC1H1, XRCC2, OFD1, MCM3, PSMB5, CCT5, CCT4, RPS7, HNRNPU, IFT88, ABRAXAS2, PCM1, EFHC1, MZT2B, BLOC1S2, CEP57, CEP112, ANKRD7, CEP20, SORBS1, IFT22, DYNLRB1, HAUS2, IFT57, ACTR10, BCCIP, TUBGCP4, RTRAF, NME7, ATP6V1D, KIF2A, DDX3X, NUDT21, NPM1, PSMA1, CETN2, CSNK1A1, RAB11A, GPSM2, PPP2R5A, CCDC14, CCDC38, NEK8, CIR1, MIB1, CEP70, CTNNBL1, IFT74, CEP19, NDN, CCDC77, PLK2, PPP1R12A, ARHGEF10, PHF1, CCP110, PRKAR2A, SKP1, CAMSAP2, CDC16, RAPSN, CEP55, DCAF12, CCDC81, NEDD1, TRAF3IP1, DYNLRB2, NEK1, ALS2, RAB3IP, RNF19A, IFT52, TTC26, CCDC88B, NDC80, GNAI2, MFAP1, SMAD4, HNF4G, ESPL1, CEP170, CEP350, PCGF5, NIN, CEP41, HAUS4, KIF15, DCAF13, VPS4B, KATNA1, TCP1, DENND1C, DYNC2LI1, RPGR, KIFAP3, ENTR1, ARL2BP, AK6, SNX10, HMMR, PRKACB, ARL2, NUP62, CTSC, CETN1, DYNC1I2, KLHL22, TPGS1, RBBP6, RAB11FIP4, AHI1, C7orf31, MASTL, CDK5RAP2, DTL, B9D1, RUVBL2, RABGAP1, |
| cerebellar mossy fiber | cellular component | DAB2IP, CACNG2, NFIB, CACNG7, LRRC4B, DLG4, SLC17A7 |
| CERF complex | cellular component | SMARCA1 |
| CGRP receptor complex | cellular component | CALCRL, RAMP1 |
| chaperone complex | cellular component | HSPA8, PTGES3, PSMG1, TSC1, BAG3, STUB1, STIP1, HSPB8, PPP5C, CDC37, PSMG2 |
| chaperone-mediated autophagy translocation complex | cellular component | LAMP2 |
| chaperonin-containing T-complex | cellular component | CCT5, CCT4, CCT7, CCT6B, CCT2, TCP1, CCT6A, CCT3, CCT8, CCT8L2 |
| checkpoint clamp complex | cellular component | RAD9B, RAD9A, RAD1, HUS1, HUS1B |
| chiasma | cellular component | MLH1, MLH3 |
| chloride channel complex | cellular component | CFTR, CLCN2, GABRB1, GABRA2, CLCN1, CLCNKA, ANO6, TTYH2, CLIC4, GABRG2, GABRB3, BEST3, GLRA3, GABRA5, CLCC1, CLIC3, PACC1, GABRB2, GABRA4, CLCNKB, GABRG1, CLDN17, CLIC5, GABRP, CLIC1, GABRD, GLRA1, CLIC6, GABRR2, TTYH1, GABRA1, GABRA3, GABRQ, CLDN4, ANO1, ANO2, SLC26A6, TTYH3, GABRR3, GABRG3, GLRA2 |
| cholinergic synapse | cellular component | PLD1, DLGAP4, CHRNA10, CHRM1, CHRNB2, CHRM2, CHRNB4, NEFL |
| CHOP-ATF3 complex | cellular component | ATF3, DDIT3 |
| CHOP-ATF4 complex | cellular component | DDIT3, ATF4 |
| CHOP-C/EBP complex | cellular component | DDIT3 |
| CHRAC | cellular component | POLE3, BAZ1A, CHRAC1 |
| chromaffin granule | cellular component | CLU |
| chromaffin granule lumen | cellular component | DBH |
| chromatin | cellular component | UBE2B, NFE2L2, UBR2, MBD2, PARK7, RB1, H2AFX, MAEL, SIN3A, MYCN, HMGN1, RBL1, EIF3E, RBL2, SLF2, COPS5, HMGN4, KLF4, CHMP2A, ORC5, HMGN3, WDR82, PLK2, RPA2, CBX1, CBX3, NSD1, NSD3, PARPBP, CAPN2, SFPQ, WAPL, HDAC2, MAGED1, SIN3B, APTX, DDX23, MACROH2A2, SMC3, OIP5, LOXL2, HTRA2, OBI1, LEMD2, SRPK1, SRPK2, UPF1, MIS18A, L3MBTL1, IST1, DSCC1, ORC3, ORC2, CREB3L2, MAF, NEDD4, CENPF, HMGA2, MEN1, RFPL1, PINK1, PLK1, SATB1, MAU2, RAD21, ANKRD17, NSD2, TMPO, MECP2, RAN, NIPBL, KDM3B, BASP1, ESCO1, STAG2, STAG1, AHCTF1, FAM111A, NCOR2, MACROH2A1, PDS5A, PDS5B, MBD4, JUNB, PML, HMGN5, FBH1, KMT2E, SMCR8, SUV39H2, RCC1, SIRT7, MBD3, MCM7, HIC1, CHMP7, MTBP, CDCA5, PPP1R10, HR, HMGN2, JUND, HLCS, AKAP8L, RFPL3, TRIM56, MCM2, ANKRD31, KIF22, FANK1, ASF1B, RFPL4A, POLA1 |
| chromatin silencing complex | cellular component | SMARCA5, SIRT2, BAZ2A, BAHD1 |
| chromatoid body | cellular component | PIWIL2, PIWIL1, DDX25, CLOCK, MAEL, TDRD7, NSUN2, EIF4E, DDX6, ARNTL, TDRD1 |
| chromocenter | cellular component | FMR1, CBX1, OIP5, MBD5, CDCA8, SALL1, CBX5, SCMH1, AURKB, INCENP |
| chromosome | cellular component | PRM1, BRCA1, FMR1, AURKC, TERT, BIRC5, PRM2, MBD1, POLQ, TNP1, TNP2, SPO11, REC8, MLH1, ATR, TEX11, SYCP3, H2AFX, 39326, H1FNT, SYCE1, SPATA22, CLOCK, BRD4, RNF8, RANGAP1, H2BFWT, HORMAD1, HORMAD2, PRDM9, LRWD1, NBN, FKBP6, IL33, TOP1, HIST1H4A, SYCP1, TEP1, STAG3, EED, H1-4, HNRNPU, CENPE, IK, PWP1, DMC1, CBX2, SEPTIN2, H2AZ2, MEIOB, KASH5, RBBP8, LLPH, TERF2IP, MCM8, CSNK1A1, PPP2R5A, FBXO11, NUP37, NEIL1, NSMCE2, NUP85, NUSAP1, MIS12, SUPT16H, ZW10, BUB3, XRCC5, NUP107, PPP2CA, PPP1R7, POGZ, NUP43, HMCES, NSD1, PRR14, NSD3, DHX36, DSN1, ZBTB4, NDC80, CDCA2, WAPL, SPDL1, CENPN, SETDB2, INTS7, OARD1, ATRX, H2BC21, ANAPC16, H2AC12, DDX23, MACROH2A2, SMC3, DYNC1I1, HMGB3, OIP5, BUB1, BUB1B, RECQL5, TNKS, DYNLT3, PPP2R5C, KMT5B, SETX, RBBP6, SHLD2, PHF6, SMC5, SPC24, CENPI, CENPT, MCM9, NSMCE4A, DTL, LOXL2, ZNF207, PHF2, DCTN3, H2AZ1, H2BC5, GTF2B, ITGB3BP, OBI1, NCAPH2, FAAP20, RNF138, EHMT2, ZFR, SRPK1, POT1, DCTN6, ZWINT, SRPK2, NCAPH, TRIP13, UVSSA, GLYR1, USP51, DCTN5, H2AJ, MIS18A, PRC1, RECQL, WDR4, TOPB |
| chromosome passenger complex | cellular component | AURKC, BIRC5, CDCA8, AURKB, INCENP |
| chromosome, centromeric core domain | cellular component | RCC2 |
| chromosome, centromeric region | cellular component | AURKC, BIRC5, REC8, SYCP3, 39326, RANGAP1, LRWD1, SYCP1, STAG3, HNRNPU, CENPE, SEPTIN2, CSNK1A1, PPP2R5A, NUP37, NUP85, MIS12, ZW10, BUB3, NUP107, PPP2CA, CBX1, CBX3, NUP43, DSN1, NDC80, WAPL, SPDL1, CENPN, ANAPC16, SMC3, DYNC1I1, OIP5, BUB1, BUB1B, DYNLT3, PPP2R5C, PHF6, SPC24, CENPI, CENPT, ZNF207, PHF2, DCTN3, ITGB3BP, DCTN6, ZWINT, DCTN5, MIS18A, DSCC1, ZWILCH, RCC2, SGO1, HJURP, NUDCD2, CENPF, SEH1L, PLK1, MAD2L1, BOD1L2, KIF2B, RAD21, RASSF2, NUP133, BOD1, CENPU, KANSL1, STAG2, GPATCH11, STAG1, AHCTF1, MAD1L1, DYNC1LI1, CENPX, PDS5A, SYCP2L, SKA2, MEAF6, PDS5B, FBXO28, CFDP1, SS18L1, SMC1A, NSL1, UVRAG, KNSTRN, TPR, TP53BP1, CKAP5, SGO2, CENPW, NGDN, SUV39H2, CENPB, CENPC, CLASP2, CDCA8, SPOUT1, PMF1, SKA1, ZNF330, PKHD1, CBX5, CDCA5, CENPM, NDE1, CENPA, CENPS, SPC25, HELLS, PPP2R1A, CENPP, CLASP1, AURKB, CENPQ, PINX1, INCENP, KNTC1, NEK2, CENPK, CENPO, NUF2, CENPH, SEPTIN7, CENPV |
| chromosome, subtelomeric region | cellular component | SIRT6 |
| chromosome, telomeric region | cellular component | TERT, ATM, SPO11, H2AFX, RNF8, LRWD1, NBN, TEP1, DMC1, KASH5, TERF2IP, PTGES3, NSMCE2, RPA2, DHX36, ATRX, TNKS, HNRNPA2B1, SETX, SMC5, NSMCE4A, SLX4, POT1, TINF2, WRAP53, SIRT2, RAD17, DCLRE1B, RTEL1, MRE11, SMG6, DOT1L, TNKS2, TERB2, NSMCE3, NSMCE1, ACD, TP53BP1, RIF1, RAD50, ERCC4, RAD51D, BLM, HMBOX1, STN1, RECQL4, ZBTB48, PINX1, ZSCAN4 |
| chylomicron | cellular component | APOE, APOB, LPL, LSR, APOA1, APOC1, APOA5, APOC3, APOH, APOBR |
| chylomicron remnant | cellular component | APOB |
| CIA complex | cellular component | CIAO2A, CIAO1, CIAO2B, MMS19, CIAO3 |
| ciliary basal body | cellular component | AKT1, ODF2, EZR, C5orf49, OFD1, IFT88, PCM1, USH1G, CFAP70, AGBL2, AGBL4, DZIP1, CEP20, CCDC113, IFT57, KIF17, CETN2, CSNK1A1, EFHC2, CCDC65, CEP19, BBS2, MLF1, TTC30A, NEDD1, TRAF3IP1, RAB3IP, IFT52, TOGARAM1, TTC26, PIN1, BBS5, IQCD, CEP41, BBOF1, DYNC2LI1, DLG5, RPGR, KIFAP3, ENTR1, PTK2, AHI1, CPLANE2, PTPN23, INTU, B9D1, PSMB4, MKKS, ARHGAP35, WDR35, WRAP73, TTLL1, CCDC88A, SPACA9, DISC1, CEP131, CCDC66, USH2A, CCDC178, TTC8, TBC1D30, CDC45, PKD2, BBS4, CSNK1D, CENPF, SDCCAG8, RTTN, CCDC170, IFT46, FAM92A, TTBK2, DZIP1L, TUBA3D, CFAP126, FAM166A, PPP1R32, ERC1, SAXO1, TTLL6, TBATA, TTLL4, C2CD3, GLE1, TAPT1, CYLD, CDKL5, TUBG1, RAB28, TTLL11, KIAA0586, IFT80, C11orf97, FAM161A, TTLL9, SSX2IP, NEK4, POC1B, WDR34, CEP290, PIFO, CFAP410, CILK1, CEP250, IFT122, CFAP100, GAS2L2, CFAP20, GAS8, PKHD1, RAB8A, ARMC9, CCSAP, LCA5, MAPK15, TBC1D7, EVC, KIF7, WHRN, BBS1, FBF1, MARK4, B9D2, TOPORS, IFT172, SSNA1, RP2, RPGRIP1L, FANK1, IFT81, SPATA7, RABL2B |
| ciliary base | cellular component | NPHP4, GLI3, IFT88, ARMC4, MOK, NEK8, PRKAR2A, TRAF3IP1, IFT52, TTC26, TULP3, CFAP36, PRKACB, SPACA9, DISC1, FAM92A, SUFU, C11orf97, WDR60, CEP126, PRKACG, CILK1, GLI1, C8orf37, IFT122, PRKAR2B, PRKAR1B, RAB8A, GLI2, FANK1, TCTEX1D2 |
| ciliary inversin compartment | cellular component | NEK8 |
| ciliary membrane | cellular component | PKD1, SEPTIN2, TXNDC15, BBS2, TMEM17, TCTN2, TCTN3, BBS5, GPR37L1, CNGA2, EPS15, BBS9, TTC8, SNAP29, PKD2, BBS4, PKD2L1, UMOD, ARL13B, SHANK2, MCHR1, SMO, TMEM67, GPR157, EFCAB7, SCNN1A, CASK, CLTB, DRD1, SSTR3, GPR161, EHD3, HHIP, CNGB1, DRD2, EVC, PTCH1, IQCE, PROM2, TSPEAR, RHO, EVC2, BBS1, MXRA8 |
| ciliary neurotrophic factor receptor complex | cellular component | IL6R, IL6ST, CNTFR |
| ciliary plasm | cellular component | NEK4, WDR34 |
| ciliary pocket membrane | cellular component | SNAP29, EHD3 |
| ciliary rootlet | cellular component | APP, KIF5B, PSEN1, KIF5A, RAB28, NEK4, PSEN2, KLC3, CROCC, RPGRIP1L |
| ciliary tip | cellular component | KIF3B, DYNC2H1, KIF3A, DYNLL1, GLI3, IFT88, WDR19, IFT22, DYNLRB1, IFT57, IFT74, TRAF3IP1, DYNLRB2, IFT52, TTC26, DYNC2LI1, KIFAP3, WDR35, RP1, IFT46, ULK3, TTC21B, SMO, CYLD, CDKL5, IFT43, IFT80, SUFU, WDR60, CLUAP1, WDR34, CILK1, GLI1, IFT122, KIF3C, ARMC9, DYNLL2, GLI2, KIF7, IFT172, IFT81 |
| ciliary transition fiber | cellular component | ODF2, DZIP1, NIN, CENPF, CEP89, SCLT1, CEP164, TCHP, FBF1, CEP83 |
| ciliary transition zone | cellular component | NPHP4, PCM1, TMEM17, TRAF3IP1, TCTN1, CFAP36, DYNC2LI1, KIFAP3, CPLANE1, B9D1, BBS9, CEP131, CCDC66, BBS4, FAM92A, TTBK2, TMEM107, MACIR, TMEM67, NEK4, CEP290, TMEM80, CDKL1, CCSAP, CC2D2A, UNC119B, RPGRIP1L, TMEM237 |
| cilium | cellular component | STRC, CATSPER1, ESR2, CATSPER2, ODF2, AKAP4, PGK2, APOA1BP, NPHP1, CABYR, LDHC, MAK, 39326, 41153, DNAH9, KIF3B, NPHP4, PKD1, DNAH12, CATSPER4, CATSPER3, CCDC103, SPAG16, DYNC2H1, TEKT4, PACRG, ADCY10, TEKT3, FAM49B, DNAH1, TEKT2, KIF3A, DYNLL1, SPA17, DNAH5, DNAH11, DNAI1, CFAP69, OFD1, GLI3, PDE4C, IFT88, SEPTIN2, CFAP70, ARMC4, CFAP65, RSPH3, LRRC6, DZIP1, TTC21A, DNAAF1, WDR19, PMFBP1, ELMOD3, TXNDC15, CEP20, DNAH6, QRICH2, IFT22, DYNLRB1, IFT57, DNAH2, KIF17, DNAH17, MOK, ATP6V1D, CETN2, CSNK1A1, NEK8, CCDC65, DAW1, IFT74, CEP19, BBS2, FHDC1, CCP110, MLF1, TTC30A, TMEM17, TRAF3IP1, DYNLRB2, RPGRIP1, CFAP53, SPATA6, IFT52, TOGARAM1, TTC26, TULP3, NUBP1, SORD, KIF19, ANKMY2, BBS5, IQCD, CFAP36, CEP41, GPR83, PPEF2, PDE6D, CCDC172, PDCL, CCDC181, BBOF1, FBXL13, DYNC2LI1, RPGR, KIFAP3, UBXN10, DRC3, CPLANE1, CATSPERB, ARL2BP, LYZL6, ARL2, CFAP298, TPPP2, OCRL, CETN1, TTLL7, TPGS1, AHI1, CPLANE2, PTPN23, TULP1, ANXA1, BBS12, KIAA1549, WDR35, PCARE, DNALI1, TTLL1, PKM, ARL3, PRLHR, BBS9, SLC9C1, EFCAB2, SPACA9 |
| cis-Golgi network | cellular component | LIMK2, CCN2, TMED5, GOLGA8A, RAB29, KDELR2, GOSR1, PIK3R1, MAN2A1, YIPF6, BCL9, KDELR3, SCFD1, RETREG1, PHTF1, UBXN2A, HOOK3, MAP6D1, RAB30, GOLGA6B, GOLGA8N, TRIP11, AKAP9, TRPC7, GOLGA8M, LRPAP1, TMED10, AZIN2, MAP6, GOLGB1, SCYL1, GOLIM4, KDELR1, COG3, GOLGA5, GBF1, FKTN, NUCB1, GOLGA2, B3GAT3, SLC10A7, COPZ2, TRAPPC6B, GOLGA6A |
| cis-Golgi network membrane | cellular component | RNF183, TRAPPC3, TRAPPC3L, BOK |
| classical Lewy body | cellular component | FBXO7 |
| clathrin adaptor complex | cellular component | AP3M1, AP3B1, AP3M2, AP2A2, AP2M1, AP2B1, AP1B1, AP4M1, AP4B1, AP2A1, AP1M1 |
| clathrin coat | cellular component | IGF2R, CLTA, AP2B1, CLTC, CLTB, KCNQ5, PANK1 |
| clathrin coat of coated pit | cellular component | SYNJ1, REPS1, EPS15, PICALM, CLTA, CLTC, REPS2, CLTB, EPS15L1 |
| clathrin coat of endocytic vesicle | cellular component | EPN2 |
| clathrin coat of trans-Golgi network vesicle | cellular component | SYNRG, CLTA, CLTCL1, CLTC, CLTB, NCALD, AP2A1 |
| clathrin vesicle coat | cellular component | EPN3, ENTHD1, CLINT1, CLTA, EPN1, NECAP1, CLTB, EPN2 |
| clathrin-coated endocytic vesicle | cellular component | AP2S1, CEMIP, INPP5F, AP2A2, CTLA4, PICALM, RAB35, SFTPB, AP2M1, MYO6, CLTA, AP2B1, DVL2, CLTCL1, CLTC, CPNE6, CLTB, SFTPD, SFTPC, AP2A1 |
| clathrin-coated endocytic vesicle membrane | cellular component | HLA-DRB1, HLA-DPB1, HLA-DQB1, APOB, HLA-DRA, HLA-DQA1, CD9, CD74, AP2S1, FZD4, SH3GL2, LDLR, FZD2, AP2A2, HLA-DQA2, AP2M1, AP2B1, HLA-DPA1, CLTC, HBEGF, FZD5, AP2A1, ROR2, TYRP1 |
| clathrin-coated pit | cellular component | TF, APP, HSPD1, DNM1L, SH3BP4, AP2S1, FNBP1, EPN3, NUMB, CEMIP, REPS1, INPP5F, FCHO1, FCHSD2, AP1S2, OCRL, TFRC, AP1S1, DAB2, RAMP2, LDLR, EPS15, CTTN, AP2A2, VLDLR, PICALM, RAB35, SNAP91, ACKR3, AP2M1, MYO6, LRP2, AAK1, AP1S3, CLTA, ADCY8, AP2B1, AMN, FCHO2, CLTCL1, CLTC, SORT1, LRP12, ITSN2, EPN1, SLC2A4, LRP1, NECAP1, CLTB, CDHR5, LRP3, AP2A1, ARRB2, LRP10, HIP1R, ITSN1, DGKD, EPS15L1, CUBN, SGIP1 |
| clathrin-coated vesicle | cellular component | SNX3, VPS41, ASTN2, MLC1, PHETA2, SH3BP4, PIK3C2A, VPS18, EPN3, NUMB, DENND1C, FCHO1, DVL1, AP1G1, OCRL, PHETA1, HAX1, DAB2, DENND1A, VPS33B, EPS15, MALL, PICALM, RAB35, SNAP91, CLINT1, MYO6, SNX9, SCAMP1, GPR107, DENND1B, VAMP3, AAK1, CLTA, BCAP31, DVL2, FCHO2, SCYL2, ABCB4, CLTCL1, CLTC, SORT1, STON1, WIPI1, SLC2A4, LRP1, CLVS1, GGA2, ASTN1, CPNE6, RGS19, VTI1A, VPS16, SNX18, VPS33A, AP2A1, HIP1R, EPN2, AP1M1, STON2, FOLR1, SGIP1 |
| clathrin-coated vesicle membrane | cellular component | AREG, FZD4, AP3B1, TGFA, CEMIP, AP1G1, SCARB2, VAMP8, TFRC, DAB2, DENND1A, RAB5A, M6PR, SYT1, AP3B2, RAB35, SLC18A3, ADRB2, DBNL, VAMP4, KIAA0319, MYO6, EREG, CD3G, LRP2, VAMP3, REEP6, ADCY8, IL7R, VAMP7, TGOLN2, SLC2A8, HBEGF, AP1B1, AVPR2, NECAP1, AVP, CD4, BTC, SYT9, HIP1R, SYT2, AP1M1, CHRM2 |
| clathrin-sculpted acetylcholine transport vesicle membrane | cellular component | SYT1, SLC18A3 |
| clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane | cellular component | HSPA8, SYT1, GAD1, DNAJC5, SLC32A1, GAD2 |
| clathrin-sculpted glutamate transport vesicle membrane | cellular component | SYT1, SLC17A7 |
| clathrin-sculpted monoamine transport vesicle membrane | cellular component | SYT1, SLC18A2 |
| cleavage body | cellular component | CSTF2, DDX1 |
| cleavage furrow | cellular component | ITGB1, 39326, 41153, NF2, PSTPIP1, SEPTIN2, RAB21, KIF20A, MYH10, RAB11A, CEP55, CIT, SVIL, RALA, HTR3A, WDR73, RAB11FIP4, MASTL, DCTN3, PSD2, KATNBL1, LIMA1, MEN1, PKN2, SPIRE1, ECT2, RDX, PITPNM1, OR2A4, PSD, ARF6, STAMBP, PSD4, SSH1, PKN1, PLEKHG6, MYH9, NDE1, RHOC, MYLK, PDXP, RAB11FIP3, SPIRE2, FSD1, SEPTIN7 |
| climbing fiber | cellular component | DAB2IP |
| CNTFR-CLCF1 complex | cellular component | CNTFR, CLCF1 |
| coated vesicle | cellular component | HSPD1, SLC28A2, CLTCL1, IDUA |
| coated vesicle membrane | cellular component | TEPSIN |
| cochlear hair cell ribbon synapse | cellular component | CACNA1D |
| cohesin complex | cellular component | SMC3, RAD21, STAG2, STAG1, SMC1A |
| collagen trimer | cellular component | C1QB, COL11A1, COL5A2, CCBE1, COL9A3, COL12A1, COL3A1, COL4A1, COL11A2, COL8A1, C1QTNF3, COL7A1, ADIPOQ, COLEC12, GLDN, COL2A1, COL23A1, C1QTNF6, COL4A2, COLEC11, MARCO, FCN3, COL9A1, COL26A1, C1QC, COL4A6, COL4A3, COL24A1, C1QTNF7, COL1A2, LOX, COL6A1, C1QTNF1, COL6A6, FCN1, COL21A1, EMILIN1, COL8A2, C1QTNF5, COL6A2, COL5A1, SFTPD, SCARA3, COL27A1, EDA, COL5A3, COL18A1, C1QA, C1QTNF9, COL15A1, MBL2, COL6A3, COL16A1, COL9A2, COL19A1, CTHRC1, COL17A1, COL22A1, WDR33, COL4A4, C1QTNF8, COL13A1, EMILIN2, COL20A1, COL6A5, COL28A1, COL25A1, C1QTNF2 |
| collagen type I trimer | cellular component | COL1A2 |
| collagen type II trimer | cellular component | COL2A1 |
| collagen type III trimer | cellular component | COL3A1 |
| collagen type IV trimer | cellular component | COL4A1, COL23A1, COL4A2, COL4A6, COL4A3, COL4A4 |
| collagen type IX trimer | cellular component | COL9A3, COL9A1, COL5A3, COL9A2 |
| collagen type V trimer | cellular component | COL5A2, COL5A1, COL5A3 |
| collagen type VI trimer | cellular component | DCN, COL6A1, COL6A3 |
| collagen type VII trimer | cellular component | COL7A1 |
| collagen type VIII trimer | cellular component | COL8A1 |
| collagen type XI trimer | cellular component | COL11A1, COL11A2, MARCO |
| collagen type XII trimer | cellular component | COL12A1 |
| collagen type XIII trimer | cellular component | COL13A1 |
| collagen type XV trimer | cellular component | COL15A1 |
| collagen type XVI trimer | cellular component | COL16A1 |
| collagen-containing extracellular matrix | cellular component | CCN1, C1QB, COL11A1, CCN2, FGL1, LTBP2, GPC2, COL5A2, LAMC1, HNRNPM, NDP, C17orf58, FIBCD1, TNN, MATN4, ANXA7, TNXB, LTBP1, FGFBP3, LGALS9, IL7, FBN2, CLEC14A, PDGFB, CTSL, CTSB, HSP90B1, ITIH2, TPSB2, SERPINB6, FBN1, MFAP4, COL9A3, TPSAB1, ADAM11, CSTB, S100A4, BCAM, CTSC, MFAP2, GPC5, ANGPTL5, SBSPON, COL12A1, LOXL2, COL3A1, COL4A1, ORM1, ANXA1, F7, COL11A2, COL8A1, SDC2, TIMP3, MFAP5, CSPG4, CRELD1, ASPN, CBLN4, MATN2, FGG, PKM, LMAN1, SERPINB9, COL7A1, ADIPOQ, ADAMTS9, SRPX2, COL2A1, S100A6, PSAP, MFGE8, LAMA4, COL23A1, MMP28, FBLN5, GPC6, MMP23B, THBS1, COL4A2, SERPINF2, MDK, SERPINB1, LAMC2, OMD, TGFB1I1, FCN3, F12, PF4, CTSG, ACAN, COL9A1, FBLN1, HDGF, PRELP, POSTN, IGFBP7, WNT2B, COL26A1, SPON1, MXRA5, ANGPTL3, FGB, C1QC, CPA3, FLG, ANXA11, COL4A6, CDON, ANGPT4, ANGPTL1, FREM3, BGN, PCSK6, SRPX, COL4A3, ANGPT1, COL24A1, ABI3BP, FRAS1, APOA1, COL1A2, HAPLN1, TGFB2, FGL2, THSD4, CTSF, EDIL3, TECTA, COL6A1, PLSCR1, CFP, COL6A6, FCN1, ANGPT2, ADAMDEC1, TNC, MST1, TGFBI, ADAMTS2, S100A8, ORM2, S100A7, TGM4 |
| commitment complex | cellular component | SNRPC, SNRPD1, U2AF2, PRPF39 |
| compact myelin | cellular component | PMP22, MBP, MAG, PLLP |
| complement component C1 complex | cellular component | C1QB, C1QA |
| concave side of sperm head | cellular component | DDX6 |
| condensed chromosome | cellular component | BRCA1, LIG4, AURKC, MSH4, MLH1, MLH3, TOP2A, SMARCA5, FANCD2, BAZ1B, AKAP8, NCAPH2, L3MBTL1, NCAPG, HMGB1, MKI67, MACROH2A1, XRCC4, RIF1, PES1, TOP3B, NCAPD2, ESRRB, INCENP, SMC2 |
| condensed chromosome inner kinetochore | cellular component | ORC2, CENPA |
| condensed chromosome kinetochore | cellular component | BIRC5, 39326, RANGAP1, HNRNPU, CENPE, SEPTIN2, CSNK1A1, NUP37, NUP85, MIS12, ZW10, BUB3, NUP107, NUP43, DSN1, NDC80, SPDL1, CENPN, ANAPC16, DYNC1I1, BUB1, BUB1B, DYNLT3, PHF6, SPC24, CENPT, ZNF207, PHF2, DCTN3, ITGB3BP, DCTN6, ZWINT, DCTN5, ZWILCH, SGO1, HJURP, NUDCD2, CENPF, SEH1L, PLK1, MAD2L1, BOD1L2, KIF2B, RASSF2, NUP133, BOD1, CENPU, KANSL1, GPATCH11, AHCTF1, MAD1L1, DYNC1LI1, CENPX, SKA2, MEAF6, FBXO28, CFDP1, SS18L1, SMC1A, NSL1, KNSTRN, TP53BP1, CKAP5, SGO2, CENPW, CENPC, CLASP2, SPOUT1, PMF1, SKA1, CENPM, NDE1, CENPA, CENPS, SPC25, CLASP1, PINX1, INCENP, KNTC1, NEK2, CENPK, CENPO, NUF2, CENPH, SEPTIN7, CENPV |
| condensed chromosome outer kinetochore | cellular component | SPDL1, BUB1B, CENPF, BOD1L2, NUP133, BOD1, SKA2, BOD1L1, SKA1 |
| condensed chromosome, centromeric region | cellular component | CENPE, CBX3, NCAPD3, NCAPG, SGO1, NCAPD2, AURKB |
| condensed nuclear chromosome | cellular component | BRCA1, MSH4, REC8, MLH1, TEX11, MLH3, H2AFX, BRD4, HORMAD1, SYCP1, DMC1, KIFAP3, AGO3, TOPBP1, CHMP1A, TTN, CCNB1IP1, RAD21, LRPPRC, TUBG1, ADD3, SHOC1, SMC1A, NIFK, RAD50, RCC1, RRS1, CDX2, P3H4, SUN2, RGS12, NEK2, NOL6 |
| condensed nuclear chromosome inner kinetochore | cellular component | DSN1, CENPK |
| condensed nuclear chromosome kinetochore | cellular component | REC8, NDC80, PELI1, BUB1, BUB1B, CENPT, CENPC, CENPA, CENPO, NUF2 |
| condensed nuclear chromosome outer kinetochore | cellular component | CCNB1, NDC80, BUB1, PLK1 |
| condensed nuclear chromosome, centromeric region | cellular component | AURKC, REC8, ATRX, KMT5B, SGO1, PLK1, SYCP2L, SS18L1, SGO2, CENPB, CENPC, KMT5C, SYCP2, CENPA, AURKB |
| condensin complex | cellular component | NCAPH2, NCAPH, NCAPG, SMC4, NCAPD2, NCAPG2, SMC2 |
| condensin core heterodimer | cellular component | SMC4, NCAPD2, SMC2 |
| cone cell pedicle | cellular component | SLC32A1 |
| cone matrix sheath | cellular component | RBP3 |
| cone photoreceptor outer segment | cellular component | RD3, TMEM237 |
| connexin complex | cellular component | GJA1, GJC2, GJD2, GJB1, GJB3, GJB5, GJD4, GJA3, GJA5, GJA4, GJB6, GJB4, GJD3, GJC1, GJA9 |
| contractile fiber | cellular component | HSPB1, GJA1, DES, PPP1R12A, CRYAB, DEK, PLEC, CDK5R1, MYH3, SMTNL1 |
| COP9 signalosome | cellular component | HSPA5, HSPA1L, DYNLL1, COPS5, COPS8, TESPA1, COPS6, COPS4, DCAF1, AMOT, STOML2, COPS2, COPS9, FLOT1, DOCK7, GRB2, BASP1, WDR6, COPS7B, HSPA6, GPS1, COPS7A, LAT, MYH9, NCKIPSD, TMOD1, AMOTL1, THEMIS, EPB41L2, HSPA1A, HSPA1B |
| COPI vesicle coat | cellular component | ARCN1, COPB2, COPB1, COPZ1, COPE, COPG1, TMED7, COPA, SCYL1, DIPK2A, COPG2, COPZ2 |
| COPI-coated Golgi to ER transport vesicle | cellular component | CCDC88A |
| COPI-coated vesicle | cellular component | ARCN1, PACS1, SEC22B, USE1, COPB1, BNIP1, ARF1, TMED2, CCDC115, TMED10, COPA, ACTR1A, DIPK2A, COPG2, PACSIN1 |
| COPI-coated vesicle membrane | cellular component | ARCN1, KDELR2, COPB2, COPB1, COPZ1, KDELR3, COPE, TMEM199, TMED2, COPG1, TMED7, COPA, KDELR1, COPG2, COPZ2 |
| COPII vesicle coat | cellular component | SEC23B, SAR1A, SEC31A, SEC24C, SEC13, KLHL12, SAR1B, PDCD6, SEC24B, SEC23A, TMED7, SEC24D, SEC31B, PEF1, SEC24A |
| core mediator complex | cellular component | MED4, MED8, MED14, MED6, MED31, MED26, MED18 |
| core TFIIH complex | cellular component | ERCC2, GTF2H3, CDK7, CCNH, GTF2H1, GTF2H4, MNAT1, GTF2H5 |
| core TFIIH complex portion of holo TFIIH complex | cellular component | GTF2H3, GTF2H4 |
| core-binding factor complex | cellular component | CBFB, RUNX1 |
| cornified envelope | cellular component | SCEL, ANXA1, TGM1, SPRR1A, SPRR3, PKP4, FLG, DSP, DSG1, CSTA, KAZN, PPL, PI3, SPRR1B, SPRR2B, CNFN, DSC3, PKP2, DSG2, EVPL, DSC2, IVL, JUP, CST6, LCE1D, SPRR2D, DSG3, PKP3, KRT2, HRNR, EVPLL, DSG4 |
| cortical actin cytoskeleton | cellular component | CDH1, NF2, DSTN, EEF1A1, SHROOM3, COTL1, MTSS2, CAPN2, GYS2, PPP1R9B, CLDN5, WDR1, UTRN, DLC1, CTTN, LANCL2, PLEKHH2, CFL2, DCDC2, ACTN2, DBNL, LLGL1, FLOT1, RDX, AKAP13, MYADM, MED28, HCLS1, PPP1R9A, LLGL2, RAPGEF3, LASP1, CORO1A, MISP, SHROOM2, CAP2, MYZAP, CAP1, MOBP |
| cortical cytoskeleton | cellular component | NSMF, NOS2, EZR, CAPZA3, EPB42, SPTBN1, CTTN, CAPZA2, DLG4, MPP1, DMTN, TRPC4, MYH9, GYPC, ACTN4, SLC4A1, TMOD1, EPB41 |
| cortical granule | cellular component | ASTL |
| cortical microtubule | cellular component | NUMA1 |
| cortical microtubule cytoskeleton | cellular component | MAPRE1, CLASP1 |
| CORVET complex | cellular component | VPS18, VPS33B, TGFBRAP1, VPS33A, VPS8 |
| costamere | cellular component | SYNM, FXR1, ANK3, SVIL, DMD, PLEC, SDC4, FLNC, AHNAK, PGM5, ANK2, KRT19, VCL, HOMER1, ILK, KRT8, DAG1, AHNAK2 |
| CRD-mediated mRNA stability complex | cellular component | HNRNPU, CSDE1, SYNCRIP, YBX1, IGF2BP1 |
| CRLF-CLCF1 complex | cellular component | CRLF1, CLCF1 |
| CSF1-CSF1R complex | cellular component | CSF1, CSF1R |
| CST complex | cellular component | STN1 |
| Ctf18 RFC-like complex | cellular component | RFC4, RFC5, RFC3, DSCC1, CHTF8, RFC2, DDX11, CHTF18 |
| Cul2-RING ubiquitin ligase complex | cellular component | ZSWIM4, ARIH1, ZSWIM5, ZER1, ZYG11B, ZSWIM8, ELOB, COMMD1, CUL2, RBX1, ZYG11A, ZSWIM6 |
| Cul3-RING ubiquitin ligase complex | cellular component | KLHL10, KEAP1, KLHL8, KLHL25, ARIH1, TNFAIP1, KLHL22, KCTD13, KLHL12, DEPDC5, KLHL7, LZTR1, KLHL41, KLHL24, SPOP, PDCD6, KLHL2, ENC1, KLHL21, KLHL20, GAN, KCTD10, KCTD17, RBX1, KCTD5, KLHL40, KBTBD8, KCTD2, PEF1, KLHL9, KLHL13 |
| Cul4-RING E3 ubiquitin ligase complex | cellular component | DCAF17, DCAF11, PLRG1, DDA1, DCAF12, DCAF13, DDB2, DTL, DCAF7, DCAF6, DCAF8, DCAF1, ERCC8, DCAF16, DCAF4, DET1, WDTC1, DCAF5, FBXW5, DCAF8L1, DCAF12L1, DCAF12L2, DCAF15, DDB1, DCAF10 |
| Cul4A-RING E3 ubiquitin ligase complex | cellular component | CRBN, COP1, TRPC4AP, ARIH1, DTL, ERCC8, DET1, CDKN1B, RBX1, DDB1 |
| Cul4B-RING E3 ubiquitin ligase complex | cellular component | DDB2, DTL, RBX1, DDB1 |
| Cul7-RING ubiquitin ligase complex | cellular component | SKP1, CUL7, FBXW8, RBX1 |
| cullin-RING ubiquitin ligase complex | cellular component | CUL9, CUL1, CUL5, ANAPC11, CUL2, CAND1, RBX1, DDB1 |
| CURI complex | cellular component | RRP7A, NOL6 |
| cuticular plate | cellular component | SPTBN1, CALB1, SNX9, CIB2, PVALB |
| cyclin D2-CDK4 complex | cellular component | CDKN2D |
| cyclin D2-CDK6 complex | cellular component | CDK6 |
| cyclin E1-CDK2 complex | cellular component | CCNE1, CCNE2 |
| cyclin E2-CDK2 complex | cellular component | CCNE2 |
| cyclin K-CDK12 complex | cellular component | CCNK, CDK12 |
| cyclin K-CDK13 complex | cellular component | CDK13, CCNK |
| cyclin-dependent protein kinase activating kinase holoenzyme complex | cellular component | ERCC2, HSPD1, CDK7, CCNH, MNAT1 |
| cyclin-dependent protein kinase holoenzyme complex | cellular component | CKS1B, CCNJL, CCNI, CCND1, CCNE1, CDK13, CDK6, CNPPD1, CCNG1, CCNG2, CDKN1A, CCNF, CDK12, CCNE2, CCNP, CCNO, CKS2, CCND3, CCNB3 |
| cyclin/CDK positive transcription elongation factor complex | cellular component | RB1, CDK9, CCNT1, CDK13, CCNK, SNW1 |
| cytochrome complex | cellular component | COX10 |
| cytolytic granule | cellular component | PRF1, GNLY, RNF19B, LAMP1, STXBP2 |
| cytoophidium | cellular component | CTPS1, CTPS2 |
| cytoplasm | cellular component | NR5A2, USP9Y, DDX3Y, GNAS, SOD1, EGFR, TGFB1, FSHB, IL1B, APOE, ESR1, TP53, CYP1A1, IL6, PGR, DCN, MMP2, AR, BCL2, TGFB3, ACE, MYH7, HSD17B1, LIF, VEGFA, CD44, IL1RN, WT1, IL11, KITLG, IL10, PTGS1, BDNF, BRD2, FAS, IL12A, CASP1, NOS3, SRD5A2, ADM, PTGS2, AHR, BRCA1, CASP4, LIG4, BRCA2, CASP6, SOX10, FKBP4, FMR1, BAX, DAZ2, HIF1A, TSSK4, DAZ4, NOSTRIN, ESR2, BCL2L2, TSSK6, DAZ1, NDRG2, AURKC, TERT, BIRC5, BGLAP, APOB, ERBB2, CDK1, HSP90AA1, ERCC1, SP1, GSTM1, NAT2, MTHFD1, CFTR, CCNB1, FLT1, ERCC2, HNF1A, FGFR2, FGFR3, XPA, DNMT1, MAPK3, MAPK1, TYK2, WEE1, CDC25A, CDC25C, AKT1, HSPA4, KDR, STAT1, CASP3, CDKN2A, GSK3B, NR0B1, CASP9, UBE2B, SNRPN, S100A12, HSF1, MDM2, E2F1, HSF2, SRY, ADCY2, ATM, GAS6, KANK1, STAT4, CASP8, EZH2, NFE2L2, UBR2, CTCFL, MBD3L1, MTR, CIB1, RNF17, PANK2, WDR11, PEG3, ARNT2, BRWD1, MBD2, DNMT3B, MTRR, GHRL, MBD1, ATP6V0A2, DMRT1, TLR4, MGEA5, TLR2, GSR, ALB, NR3C1, GAPDH, HSPB1, APP, ITGB1, ENO1, GPX1, ITGA5, VIM, GSTP1, CBSL, CLU, FGFR1, F3, SRD5A1, TRH, GSTT1, CTNNB1, CBS, GPX4, HSPA |
| cytoplasmic cyclin-dependent protein kinase holoenzyme complex | cellular component | CDK14, CCNY |
| cytoplasmic dynein complex | cellular component | DYNLT1, DYNLL1, DYNC1H1, DYNLRB1, DYNLRB2, DYNC2LI1, DYNC1I1, SNX4, DYNLT3, DYNC1I2, DYNC1LI2, DYNC1LI1, WDR60, WDR34, TPR, DCTN4, NUDCD3, DYNLL2, TOPORS, TCTEX1D2 |
| cytoplasmic exosome (RNase complex) | cellular component | EXOSC9, GTPBP1, EXOSC7, EXOSC5, EXOSC3, EXOSC8, DIS3, CARHSP1, EXOSC4, DIS3L, EXOSC6, EXOSC2 |
| cytoplasmic microtubule | cellular component | BIRC5, DYNLT1, SAA1, DCXR, SELENOS, FHDC1, SERP1, TOGARAM1, BCL10, ENKD1, REEP1, DYNC2LI1, MAPRE3, ARL3, SS18, SPACA9, BICD1, CLMP, GRAMD2B, SNPH, CYP2A6, CKAP2, REEP4, APC, ODF3L2, CYLD, TUBG1, CLIP1, ARHGAP18, C4orf47, SRPRB, BCAS3, GTSE1, MAPRE1, HDAC6, TPT1, MID1, CLASP2, TUBGCP2, SCTR, RAB3D, APC2, MTUS2, HID1, TUBG2, TOGARAM2, CLASP1, CLIP2, REEP3 |
| cytoplasmic microtubule bundle | cellular component | NUMA1 |
| cytoplasmic periphery of the nuclear pore complex | cellular component | RANGAP1, RANBP2 |
| cytoplasmic ribonucleoprotein granule | cellular component | DDX3Y, FMR1, PABPC1, ACTB, CDC42, PSMC2, RPS4X, RPS6, HNRNPU, RPL6, UPF2, EID1, RPLP0, SNCAIP, IQGAP1, FXR1, SARNP, ZC3H12A, USP3, LSM14A, STAU1, SNRPB2, DYNC1I1, PCBP1, DCP2, CASC3, ROCK2, AGO3, SOCS1, EDC4, MYH1, SERPINB1, CKAP4, PATL1, NFKBIZ, FLG, PARD3, POLDIP3, EIF4E, TUBB, DDX6, RPL28, TAF5L, FXR2, CHTOP, GHR, RAC1, KHNYN, EDC3, POLI, SMN1, PITPNM1, HOXD10, TSTD1, YTHDF2, BARD1, MOV10, DCP1A, NCL, TUT4, MCC, ZC3H12D, ICOSLG, CTSH, GABPB1, SHB, INA, MAP1LC3C |
| cytoplasmic side of apical plasma membrane | cellular component | EZR, FRMD1, EXOC1, C2CD2L |
| cytoplasmic side of dendritic spine plasma membrane | cellular component | PPP1R9B |
| cytoplasmic side of early endosome membrane | cellular component | RAB21, RAB5A, LITAF |
| cytoplasmic side of endoplasmic reticulum membrane | cellular component | THADA, PTPN1, EPM2AIP1, DNAJB2 |
| cytoplasmic side of late endosome membrane | cellular component | LITAF, CDIP1 |
| cytoplasmic side of lysosomal membrane | cellular component | EEF1A1, BORCS5, EEF1A2, LITAF, CDIP1 |
| cytoplasmic side of membrane | cellular component | RASAL3 |
| cytoplasmic side of mitochondrial outer membrane | cellular component | CISD1, LRRK2 |
| cytoplasmic side of nuclear pore | cellular component | NUP214 |
| cytoplasmic side of plasma membrane | cellular component | PTEN, KIT, G6PD, CDH1, ACP1, RAB21, CHMP4A, HTRA2, TRAF3, CHMP4B, GEM, PTP4A1, PKP4, PTPN22, PTPRC, DSG1, BIRC2, PGM5, MAP2K2, RGS2, DLG1, PPP3CA, LITAF, TRAF6, DIABLO, CD2, CACNB4, IKBKB, PTPN7, CHMP4C, GNB1L, TRAF5, TH, CHMP7, JUP, ATP2B1, AKAP5, PTPN4, TRAF1, NTSR1, RNF31, AJAP1, ATP2C2, SLC4A1, TRAF2, ASPSCR1, EPB41, PTPN3, GM2A |
| cytoplasmic side of rough endoplasmic reticulum membrane | cellular component | GNRH1, RPL27, RPS29, RPS28 |
| cytoplasmic stress granule | cellular component | PABPC1, PUM2, NANOS3, DDX1, DDX3X, G3BP1, PUM1, DDX19B, DYRK3, DHX36, CSDE1, TRIM25, LSM14A, C9orf72, STAU1, TIA1, ZFAND1, ATXN2L, CASC3, ENDOV, YBX1, CAPRIN1, MBNL1, TIAL1, RNF135, CTSG, ROCK1, MCRIP2, GRB7, EIF4E, DDX6, PRRC2C, MCRIP1, EIF2S1, RC3H1, NUFIP2, RBM4, LARP1, RBFOX1, NXF1, G3BP2, ZFP36, PRKAA2, HABP4, PABPC5, MOV10, PQBP1, BPI, GIGYF2, OGFOD1, HNRNPK, PABPC4, RPTOR, KHSRP, RBPMS, IGF2BP1, LARP4B, ATXN2, UBAP2L, LIN28A, DDX19A |
| cytoplasmic ubiquitin ligase complex | cellular component | ATG3 |
| cytoplasmic vesicle | cellular component | GNAS, SOD1, IL1B, NOSTRIN, ERBB2, FGFR2, FGFR3, KDR, FASLG, ATM, TLR2, APP, ITGB1, ITGA5, CLU, FGFR1, HFE, ADAMTS1, CD46, MEFV, CLK3, SPACA3, DNM1L, NTRK1, MYRIP, IL33, AGFG1, SNX3, PAM, AQP2, ARCN1, VPS41, RAB9A, NBR1, GLIPR1L1, CFAP65, PRRT2, MARCHF3, NRSN1, COPS5, OPTN, RAB21, LGALS8, TRAK2, ASTN2, ATP10B, CXCR4, RAB11A, SCAP, GRM4, MLC1, RABEP1, SEC23B, PHETA2, SLC30A9, MIB1, RGL4, SNX19, USP6NL, IFT74, TMEM74, MAP1LC3A, SH3BP4, AP3M1, PIK3C2A, ATP8B3, ATP6AP2, KDELR2, USP14, RAB38, SYPL1, VMA21, ARAP1, FNBP1, RAB11FIP5, MFF, VPS18, ZDHHC8, KIAA1210, SNX7, SNX6, SYNGR1, SEC31A, COPB2, GABRA2, COPB1, COPZ1, SREBF2, CNST, RHOU, SPACA4, MARVELD3, C9orf72, EPN3, RAB6B, FLRT1, PIKFYVE, SH3GLB1, AP3B1, KDELR3, PDE6D, TGFA, ECE2, EEF1AKMT4-ECE2, NUMB, RND2, SEC24C, SEC13, WLS, C2CD5, DENND1C, TP53INP1, ANKRD27, CHMP4A, CD93, LAMP3, DVL1, GIPC1, WIPF1, AP1G1, MPDZ, SNAPIN, AP1S2, AP3S2, PSMC5, OCRL, KLC1, TPRG1L, FNBP1L, RAB11FIP4, ZDHHC17, PHETA1, AQP11, ARRDC4, GOLGA1, RAB3C, CMTM3, COPS4, TRIM9, SEMA4C, RHBG, |
| cytoplasmic vesicle lumen | cellular component | FASLG, ADA, SERPINI1 |
| cytoplasmic vesicle membrane | cellular component | YWHAQ, AQP2, RAB9A, RAB11FIP2, MARCHF3, RAB21, ATP10B, RAB11A, ZNRF2, SNX19, AP3M1, SLC12A2, SYPL1, ZDHHC8, SNX7, GABRA2, FLRT1, PDE6D, ECE2, RALA, WLS, C2CD5, ANKRD27, CHMP4A, LAMP3, AP1G1, RAB4A, AP1S2, AP3S2, ZDHHC17, AQP11, RHBG, ANXA1, RYR1, AP3M2, AP1S1, AP3S1, RYR2, IFNGR2, IL15RA, TAOK2, CLIC4, VAMP1, STXBP5, SNX21, KIF1B, GABRG2, GABRB3, PKD2, ULK2, SNX33, ABCC11, SNX5, AP1G2, ITPR3, MFSD10, TMED2, DTNBP1, PACSIN2, SNX24, SMAGP, SAYSD1, SNX9, MARCHF11, SCAMP1, GABRB2, APPBP2, AP1S3, ENTPD7, NPC1L1, CLTA, CLIP1, SPIRE1, ARHGAP21, CADPS2, SH3BP5, TMEM67, DENND4C, KIFC3, GABARAPL1, NSG2, CLTCL1, CLTC, SORCS2, SORT1, SLC2A8, GDE1, MYO5B, ITPR1, ZDHHC13, GPRC5A, LNPEP, SLC2A4, KCNJ4, AP1B1, STING1, VOPP1, SNX15, GPRC5B, SYNGR2, HTT, AQP6, ITPR2, AGTRAP, MYOF, TH, CLTB, RNF144A, MARCHF1, MARCHF8, SNX18, GPRC5C, CALY, MYO1C, FZD6, GABRA1, BACE1, GRIN2A, YKT6, DYSF, VAMP5, NSG1, SLC18A2, LRIG3, AHNAK2, SNX22, TMEM184A, TRIM72, NMNAT2, MCOLN1, DISP3, TRPM2, SCNN1B, SNX17, BAIAP2L2, SPIRE2, AP1M1, SLC26A6, SLC |
| cytoskeletal calyx | cellular component | CYLC2, CCIN, CYLC1 |
| cytoskeleton | cellular component | KITLG, NOS3, BRCA2, FKBP4, NOSTRIN, AURKC, BIRC5, CDK1, CCNB1, ERCC2, MAPK3, MAPK1, TYK2, S100A12, CASP8, CIB1, NR3C1, KRT1, GAPDH, HSPB1, VIM, CTNNB1, HSPA2, TMSB4X, GNAI1, ODF2, AKAP4, NSMF, BRSK2, TUBB2B, YES1, SRC, ARHGDIA, NPHP1, MEFV, CABYR, EZR, MAK, ACTB, CDC42, TWF1, CDC20, TUBB3, 39326, 41153, PICK1, DNAH9, SYNM, KIF3B, NPHP4, TPM1, ANK1, NF2, RANGAP1, AIF1, DYNLT1, TUBA4A, TUBA3C, KIF26B, MAST2, KIF6, DNAH12, SPAG16, DYNC2H1, ACTRT2, TEKT4, MYO19, ADCY10, KATNB1, TEKT3, RASSF1, KLC4, TUBA8, DNAH1, STARD9, LRWD1, TEKT2, MYO15A, KIF3A, WASL, 38231, S100A9, DYNLL1, DYNC1H1, DNAH5, DNAH11, DNAI1, SHTN1, XRCC2, PSTPIP1, OFD1, ARL6IP5, KIF5B, CCT5, HINT1, CCT4, CLNS1A, RPS7, PPP2R2B, HNRNPU, CENPE, IFT88, IK, CAMK2B, ABRAXAS2, SEPTIN2, PCM1, USH1G, EFHC1, CFAP70, ARMC4, CAMSAP1, KANK4, AGBL2, AGBL4, MZT2B, BLOC1S2, CFAP91, RSPH3, CEP57, DZIP1, CEP112, DNAAF1, WDR19, CCDC110, SHROOM3, ARPC1A, ELMOD3, CEP20, TTC25, CORO1B, SORBS1, DNAH6, CCDC113, DYNLRB1, HAUS2, IFT57, ACTR10, DNAH2, BCCIP, KIF17, HECW2, D |
| cytoskeleton of presynaptic active zone | cellular component | RIMS2, RIMS1, BSN, RIMS3, RIMS4 |
| cytosol | cellular component | SOD1, IL1B, TP53, AR, BCL2, HSD17B1, FAS, CASP1, NOS3, ADM, AHR, CASP4, CASP6, GNAS, FKBP4, BAX, IL18, BAK1, HIF1A, BCL2L2, FKBPL, DNMT3L, NDRG2, BIRC5, CCNB2, APOB, CDK1, HSP90AA1, GSTM1, HMOX1, NAT2, MTHFD1, CFTR, CCNB1, MAPK3, MAPK1, TYK2, CDC25A, CDC25C, AKT1, HSPA4, STAT1, CASP3, CDKN2A, MTHFR, GSK3B, CASP9, S100A12, HSF1, MDM2, CASP8, NFE2L2, UBR2, MTR, PANK2, MTRR, GHRL, MGEA5, GSR, IL1A, GAPDH, HSPB1, APP, ENO1, GPX1, VIM, GSTP1, CLU, FGFR1, CSNK2A2, EDNRA, GSTT1, CTNNB1, CBS, GPX4, STAT3, AKR1C3, MTOR, BAG6, SULT1E1, HSPA2, PTEN, TMSB4X, CSNK2B, PRDX4, ODF2, ASRGL1, BAD, PARK7, A2M, CAT, INSR, YES1, PABPC1, SRC, NOS2, CHKA, PIK3CA, MAPK8, XDH, SULT1A1, ARHGDIA, IL2, CYCS, SLC7A5, C1QBP, KHDRBS1, LMTK2, APOA1BP, MUC13, PDXK, GAPDHS, NPHP1, MEFV, IDH1, RAF1, LDHC, HSPA1A, HSPA1B, HSPD1, G6PD, EZR, GJA1, COMT, CALB2, F2R, YWHAQ, OXTR, PRDX2, EPHX2, HSPA1L, PPARG, SOX2, ACTB, CDC42, RAP1A, LIPE, PTPN11, MCL1, SOS1, FOXO1, CDC20, SHH, 39326, UAP1, DUSP6, PLCZ1, DICER1, RNF114, DNM1L, KIF3B, PLA2G6, NPHP4, |
| cytosolic aryl hydrocarbon receptor complex | cellular component | AHR |
| cytosolic large ribosomal subunit | cellular component | RPL4, RPL3, RPL5, RPL27, RPL31, RPL24, RPL6, RPL10L, RSL24D1, RPLP0, RPL29, RPL15, RPL7A, RPL32, RPL7, RPL13, RPL11, RPL19, RPL39L, RPL35A, RPL21, RPL37A, RPL41, RPL9, RPL30, RPL38, RPL13A, RPL35, RPL36AL, RPLP1, RPL39, RPL8, RPL3L, RPL27A, RPL18A, RPL12, RPL22, RPL28, RPL34, RPL10A, RPL14, FXR2, RPL37, RPL36, RPL10, RPL26L1, RPLP2, RPL23A, RPL18, UBA52, RPL7L1, RPL36A, RPL17, RPL23, RPL26 |
| cytosolic proteasome complex | cellular component | PSMC6, PSMD14, PSMC5, IDE, PSMC4, UBQLN4 |
| cytosolic ribosome | cellular component | RPL13, PPARGC1A, APOD, NUFIP1, RPL26 |
| cytosolic tRNA wobble base thiouridylase complex | cellular component | CTU1 |
| Dbf4-dependent protein kinase complex | cellular component | DBF4, DBF4B |
| DBIRD complex | cellular component | CCAR2, ZNF326 |
| death-inducing signaling complex | cellular component | FAS, CASP3, CASP8, FADD, CFLAR, TRADD |
| dehydrodolichyl diphosphate synthase complex | cellular component | NUS1 |
| delta DNA polymerase complex | cellular component | POLD2, POLD4, POLD1 |
| dendrite | cellular component | APOE, IL6ST, FMR1, GNAS, BGLAP, STAT1, GSK3B, ADCY2, CIB1, GNRH1, GNAO1, MTOR, SEMA3A, NSMF, IL1RAPL1, NRG1, BMPR2, NCOA2, COMT, SUMO1, TUBB3, DICER1, WFS1, NTRK1, RANGAP1, ADCY10, TP63, ANXA5, GOPC, PRNP, HSPA8, GABRB1, FUS, RPS6, PPFIA1, GLRX5, KIF17, LSM1, TRAK2, COBL, MAX, DYRK1A, PLK2, HNRNPR, KIF1C, MARK3, RCVRN, PPT1, FXR1, ANK3, ZNF385A, ALS2, DHX36, ABITRAM, NPTN, GNAI2, GNB3, CAPN2, GABRA2, RAB27A, GRIN1, MARK2, NLGN4X, NIN, C9orf72, PPP1R9B, RTN4R, FZD4, MAPK8IP1, SGCE, STAU1, CYBB, RACK1, PURA, GRIPAP1, DAB2IP, KIRREL3, ZDHHC5, ACAD9, ATXN10, INPP5F, SNX14, DVL1, TRIM3, MPDZ, NEURL1, ANXA3, EPHB2, HRH1, STX3, CNN3, TTLL7, TPGS1, AQP11, TRIM9, BRINP2, KCND3, ARFGEF2, CPLX1, CASC3, GRK4, BMPR1A, HCFC1, GNB1, RBM3, DENND1A, GLRX2, ZWINT, NQO1, GNAZ, RAB5A, NTF4, SLC1A4, CACNA1C, MPP2, CTTN, ADNP, KCND2, TAOK2, CACNG3, HTR7, DRP2, CAPRIN1, FZD3, HOMER2, IGSF9, OPA1, KIF1B, GLRX3, WDR47, CALB1, CYBA, GABRG2, NTRK2, SARM1, ERO1A, SPG11, FEZ1, KCND1, RBM8A, N4BP3, GLRA3, SYN1, ELK1, CRHBP, GABRA5, EPHB1, |
| dendrite cytoplasm | cellular component | SOD1, MAPK1, KIF5B, HNRNPU, KCNAB1, KIF17, TRAK2, CANX, ZC3H14, SFPQ, PURA, WLS, ABHD12, UHMK1, HPCA, MAP2K4, KIF5A, MAP2, CDKL5, GRIK3, GABARAPL1, ADA, WASF1, DLG4, KLHL17, HIP1R, GRIK2, LRRK2 |
| dendrite membrane | cellular component | TACR3, GABRA2, SGCE, WLS, MPP2, GABRG2, HPCA, ATF4, GABRA5, GABRA4, KCNC4, GABRG1, KCNB1, GABARAPL1, OPRD1, PALM, ATP2B1, THY1, GABRA1, KCNC1, KCNC2, AKAP5, GABRA3, GRIA1, DAGLA, KCNC3, GABRG3 |
| dendrite terminus | cellular component | IFT57, IFT52, SLC32A1 |
| dendritic branch | cellular component | MAP2, AKAP9 |
| dendritic filopodium | cellular component | FMR1, FXR1, MAP2, FXR2 |
| dendritic growth cone | cellular component | COBL, MAPK8IP1, TAOK2, MAP2, CDKL5, CYFIP1, PTCH1 |
| dendritic microtubule | cellular component | ZNF804A |
| dendritic shaft | cellular component | FMR1, GSK3B, APP, CTNNB1, BAIAP2, RTN4R, NSF, KIRREL3, KIRREL1, GIPC1, JPH4, MPP2, CNIH3, PSEN1, MAP2, CRIPT, SLC8A1, ARHGEF2, EPHA4, LPAR1, ILK, DLG3, PRKAR2B, PREX1, ZMYND8, PSEN2, CNIH2, SYNDIG1, LZTS1, NTSR1, SEZ6, GRM7, ZNF804A, GPER1 |
| dendritic spine | cellular component | FMR1, GSK3B, APP, ITGB1, PTEN, NCOA2, COMT, ARF4, FUS, PSMC2, PRRT2, CANX, MYH10, GRM3, BAIAP2, EEF2K, FXR1, ASIC2, ALS2, TANC2, ARHGAP32, GRIN1, PPP1R9B, CRYAB, DVL1, GIPC1, NEURL1, KCNA4, GPM6A, PTK2, CNN3, KCNN1, FBXO2, ARFGEF2, CTNND1, PPFIA2, BCR, ABR, ABI2, ARHGAP33, MPP2, CTTN, SYNPO, KCND2, FCGR2B, CTTNBP2, DNM3, DGKI, CALB1, NTRK2, MX1, ACTN2, NEDD4, CPEB4, DTNBP1, SHANK2, SLC8A3, MOB4, STRN, SRGAP2, CD3E, GRIA2, ATP1A2, FXR2, PDE4B, TIAM1, CDK5R1, TENM2, CRIPT, FARP1, RGS10, RAC1, PPP3CA, SLC8A1, CYFIP1, ABHD17B, SORCS2, APBA2, DNAJB1, EPHA4, HOMER1, STRN4, NR1D1, EPHA1, DLG4, APBA1, LPAR1, SEPTIN11, PPP1R9A, PSD, P2RX6, OPHN1, MT3, KCNJ2, PTPRO, LRRC4, ADGRB1, GRID2, PALM, MX2, DRD1, PRKAR2B, ZMYND8, RPH3A, GRIA3, PDLIM4, STX4, CNIH2, NGFR, ITPKA, RAB8A, GRIN2A, P2RX4, SYNDIG1, LZTS1, RGS14, AKAP5, DNM1, APBB1, DRD2, NTSR1, ARRB2, GRIA1, P2RX3, SHANK1, LZTS3, HIP1R, FRMPD4, ITSN1, SEZ6, ABHD17A, IGF2BP1, SLC8A2, PTK2B, ARHGAP44, KCNN2, CAMK2A, MAP1B, HAP1, ZNF804A, ANKS1B, DOCK10, ASAP1 |
| dendritic spine cytoplasm | cellular component | BAIAP2 |
| dendritic spine head | cellular component | FUS, PPP1R9B, PPP1R1B, DNM3, HPCA, MX1, SRGAP2, MX2, DNM1, NRGN, GPER1 |
| dendritic spine membrane | cellular component | ATP6AP2, PPP1R9B, DDN, PALM, ATP2B1, GRIA1, DAGLA, SHISA7, KCNC3, SHISA6, ITGA8, TRPV1, GPER1 |
| dendritic spine neck | cellular component | SRI, FXR1, PPP1R9B, PPP1R1B, FXR2, PPP1R9A |
| dendritic tree | cellular component | RIT2, ELOVL5, CX3CR1 |
| dense body | cellular component | PIWIL2, PIWIL1, ACTB, ACTG1, SND1 |
| dense core granule | cellular component | SOD1, MYRIP, SYT1, SYT5, CRHBP, BACE2, NCS1, SCG2, SYT9, ECRG4, SYT7, BAIAP3, SYT2 |
| dense core granule membrane | cellular component | VPS13C, ADAM8 |
| dense fibrillar component | cellular component | SNU13, FBL |
| dentate gyrus mossy fiber | cellular component | MAPK8IP1 |
| Derlin-1 retrotranslocation complex | cellular component | SELENOS, DERL1, HM13, SEL1L, RNF139, SYVN1, AMFR |
| Derlin-1-VIMP complex | cellular component | SELENOS, DERL1 |
| desmosome | cellular component | JAM3, KLHL24, POF1B, PKP4, DSP, DSG1, PNN, KAZN, B4GALT1, PPL, PERP, TCHP, DSC3, PKP2, DSG2, EVPL, DSC2, JUP, DSG3, PKP3, KRT80, DSG4 |
| deuterosome | cellular component | DEUP1, SASS6, CCDC78 |
| discoidal high-density lipoprotein particle | cellular component | APOA1, APOM |
| distal axon | cellular component | BRSK1 |
| distal dendrite | cellular component | MAP2 |
| DNA ligase III-XRCC1 complex | cellular component | LIG3 |
| DNA ligase IV complex | cellular component | LIG4, XRCC4, NHEJ1 |
| DNA polymerase complex | cellular component | POLD2 |
| DNA polymerase III complex | cellular component | CRCP |
| DNA recombinase complex | cellular component | RAG2 |
| DNA repair complex | cellular component | ATM, RCOR1, TP53BP1, PHF21A |
| DNA replication factor A complex | cellular component | XPA, PLRG1, RPA2, PRPF19, PURA, RPA1, ERCC5, SMARCAL1, BCAS2, RPA3, STN1, HELB, PURB, TONSL, CDC5L |
| DNA replication factor C complex | cellular component | PCNA, RFC4, RFC5, RFC3, RFC2, RFC1 |
| DNA replication preinitiation complex | cellular component | ORC3, CDC45 |
| DNA topoisomerase complex (ATP-hydrolyzing) | cellular component | TOP2A |
| DNA-dependent protein kinase-DNA ligase 4 complex | cellular component | LIG4, ATP23, PRKDC, XRCC4 |
| dolichol-phosphate-mannose synthase complex | cellular component | DPM2, DPM1 |
| dopaminergic synapse | cellular component | CHRNA5, NLGN2, RAB3B, ADRA1A, FLOT1, DRD3, CHRNA6, CHRNB2, CHRNA4, SLC18A2, DRD2, SLC6A3 |
| DRM complex | cellular component | LIN52 |
| DSIF complex | cellular component | SUPT4H1, SUPT5H |
| Dsl1/NZR complex | cellular component | ZW10, NBAS, RINT1 |
| DUBm complex | cellular component | ENY2 |
| dynactin complex | cellular component | ACTR10, DCTN3, DCTN6, DCTN2, ACTR1A, DCTN4, ACTR1B |
| dynein complex | cellular component | DNAH9, DYNLT1, DNAH12, DYNC2H1, DNAH1, DYNLL1, DYNC1H1, DNAH5, DNAH11, DNAI1, DNAH6, DYNLRB1, DNAH2, DNAH17, DYNLRB2, TCTE3, DYNC2LI1, DYNC1I1, DYNLT3, DYNC1I2, DNALI1, DISC1, DYNC1LI2, DNAL1, DNAH3, DNHD1, DNAI2, DNAL4, DYNC1LI1, DNAH10, DNAH8, DCTN2, HDAC6, DYNLL2, DNAH14 |
| dystroglycan complex | cellular component | SGCB, SGCD, DAG1, SGCA |
| dystrophin-associated glycoprotein complex | cellular component | DMD, SGCE, UTRN, SNTG2, SNTG1, SGCB, CAV3, PGM5, SGCD, KRT19, SNTB2, SSPN, SNTB1, KRT8, DAG1, SNTA1, SGCA |
| early endosome | cellular component | APOE, APOB, CFTR, MAPK3, MAPK1, KDR, TF, HFE, IGF2R, LMTK2, HSPD1, GJA1, F2R, RAP1A, NTRK1, ANXA2, NF2, USP8, SNX3, VPS41, SIAH1, DERL2, ACKR4, RAB21, TRAK2, ASTN2, VPS26A, SNX16, CXCR4, MLC1, RABEP1, PHETA2, PARM1, ITCH, TSG101, VPS29, NOX1, UHRF1BP1L, RAB29, DIAPH2, RAB38, CCDC93, ALS2, RAB11FIP5, VPS18, MAGEL2, VPS28, SNX6, SIAH2, VCAM1, RAB1A, WASHC5, AP1AR, LAPTM4B, WDFY1, MMGT1, NIPA2, DTX3L, SNX27, DERL1, STX8, PLPP2, ECE1, NUMB, RND2, WLS, WASHC2A, ENTR1, ANKRD27, SH3GL2, LAMP3, INPP5F, WASHC3, CTNS, TRIM3, SNX4, OCRL, PHETA1, ARRDC4, APH1A, VAMP8, PTPN23, LIPG, TFRC, ANXA1, WASHC4, VPS26B, PLD4, SH3GL3, VPS33B, HGS, LDLR, RAB5A, EPS15, RAB31, RAB32, ZFYVE16, HAVCR2, VIPAS39, RAB20, RHOD, TOM1, CACNG7, PICALM, PTP4A1, RPS6KC1, KIFC1, CHMP1A, ANKFY1, RABGEF1, RAB22A, MYO5A, ADRB2, NTRK2, SLC30A10, KIF16B, SNX5, MGRN1, ACKR3, NAPEPLD, EHD4, GGA3, DBNL, PACSIN2, TRAK1, ANGPTL3, STX7, TMEM127, LRP6, PSEN1, RAB14, RAPGEF1, KIAA0319, ST8SIA2, TM9SF4, CNTNAP2, GPR107, SLC2A13, ATP9A, FLOT1, APOA1, PRDX3, MAP |
| early endosome lumen | cellular component | B2M, RAB38, RAB32, LNPEP, PDLIM4 |
| early endosome membrane | cellular component | EGFR, HLA-B, HLA-A, CFTR, HLA-E, B2M, HLA-G, NTRK1, HLA-C, SNX3, MARCHF3, STX12, TMEM9B, RAB21, SNX16, RABEP1, SNX19, ITCH, TSG101, RAB11FIP5, SNX6, SNX2, MMGT1, DTX3L, SNX27, TMEM165, PIKFYVE, PLPP2, GRIPAP1, WLS, WASHC2A, MTMR4, VTI1B, INPP5F, SNX4, RAB4A, OCRL, RUFY1, VAMP8, ANXA1, GPNMB, PMEPA1, SH3GL3, VPS33B, HGS, RAB5A, EPS15, RAB31, ZFYVE16, SNX20, STAM, SNX8, WNT3A, STEAP4, SNX21, CD274, RCC2, RABGEF1, WDR91, NTRK2, KIF16B, SNX5, DKK1, EPHB1, NAPEPLD, EHD4, GGA3, HSD17B6, STX7, LRP6, PSEN1, RAB14, WDR81, KIAA0319, INPP4A, CMTM6, LLGL1, UBXN6, ATP9A, STAM2, CLCN3, OSBPL6, SNX13, EEA1, TICAM2, LITAF, NSG2, PML, MR1, SORCS2, PI4K2A, BOK, SNX12, EPHA4, VAC14, MCOLN3, SORL1, INPP5B, CLN3, APPL2, RAB5B, ARF6, CLVS1, TMEM163, GGA2, GGA1, FZD5, FGD2, MARCHF1, SLC9A6, PDLIM4, RAB5C, CLCN4, MARCHF8, EPHA8, SYNDIG1, APPL1, NSG1, ABCA7, GRIA1, TMEM184A, PLD3, BAIAP3, SH3GL1, ZFYVE28, DAGLA, LDLRAD4, CD8B, SLC39A14, ZFYVE9, HLA-F, CLIP3, PLEKHF2, WASHC2C, CAV1 |
| early phagosome | cellular component | SNX3, SYK, RAB5A, UNC13B, APPL2, TLR9, PLA2G5, TLR7, APPL1, SYT7, UNC93B1 |
| early phagosome membrane | cellular component | RAB31, APPL2 |
| EARP complex | cellular component | VPS52, VPS53, VPS50, VPS51, EIPR1 |
| ectoplasm | cellular component | GYS2 |
| egg coat | cellular component | OVGP1, ZP3 |
| EGO complex | cellular component | RRAGA, RRAGB, RRAGD |
| EKC/KEOPS complex | cellular component | GON7, TPRKB, LAGE3, OSGEP, TP53RK |
| elastic fiber | cellular component | MFAP4, FBLN5, FBLN1, ELN |
| Elg1 RFC-like complex | cellular component | RFC4, ATAD5, RFC1 |
| Elongator holoenzyme complex | cellular component | ELP2, ELP4, ELP5, ELP1, ELP3, ELP6 |
| elongin complex | cellular component | ELOC, ELOA2, ELOB, ELOA3, ELOA |
| EMILIN complex | cellular component | EMILIN1 |
| endocytic vesicle | cellular component | EGFR, TF, IGF2R, KIF5B, RABEP1, RAPGEF2, RALA, PLD1, DAB2IP, GIPC1, RAB11FIP4, NRXN1, RAPGEF6, RAB5A, RAB20, AMOT, MTSS1, TIRAP, EHD4, STX7, MYO6, STAM2, APOA1, LRP2, AMN, DPP4, HEATR5B, CD2AP, HYAL2, LPAR1, GOLIM4, PIK3C2B, AVPR2, DRD3, RAB5B, ARF6, EHD2, SFTPD, EHD3, RAB17, DYSF, LPAR2, PLEKHG5, DRD2, ARRB2, RAB11FIP3, ITSN1, CUBN, SH3KBP1, HEATR5A |
| endocytic vesicle lumen | cellular component | APOE, APOB, HSP90AA1, SAA1, HSPH1, HSP90B1, HBB, APOA1, HYOU1, HP, HBA1, CALR |
| endocytic vesicle membrane | cellular component | HLA-DRB1, HLA-DPB1, NOS3, NOSTRIN, HLA-DQB1, MDM2, HLA-DRA, HLA-DQA1, CD9, PICK1, WASL, CAMK2B, CAMK2D, CD74, AP2S1, RPS27A, WLS, CACNG2, SCARB2, WNT7B, WNT4, COLEC12, SCARB1, CACNG3, AP2A2, WNT3A, HLA-DQA2, MARCO, AP2M1, SMO, STAB1, GRIA2, ENTPD7, AP2B1, HLA-DPA1, UBC, UBA52, HBEGF, DLG4, CACNG4, LRP1, GRIA3, GPR161, CAMK2G, UBB, CD163, AP2A1, GRIA1, PTCH1, WNT3, SCARF1, WNT6, WNT7A, WNT5B, CAMK2A, STAB2, CACNG8, CD36, CAV1 |
| endolysosome | cellular component | TLR9, HRG |
| endolysosome lumen | cellular component | CTSK, CTSL, CTSB, LGMN, CTSS |
| endolysosome membrane | cellular component | AP2S1, LDLR, AP2A2, AP2M1, CLTA, AP2B1, CLTC, TLR9, TLR7, TLR3, AP2A1, CLEC16A, PCSK9 |
| endomembrane system | cellular component | MTOR, DNM1L, ATP6V1B1, RAB9A, STX12, RNF34, IFT22, RAB18, NRBP1, RAB21, PGRMC2, JAK2, ATP6V1B2, RAB11A, SEC23B, LCLAT1, RAB2B, RAB40A, MAP1LC3A, RAB29, RAB38, ARL6IP1, CDC42EP5, RAB27A, RAB1A, LAPTM4B, RAB6B, STX8, BCL2L11, STX10, RAB2A, STX5, WLS, CYB5D2, SLC9A3R1, RAB4A, STX3, RABL3, RAB3C, BPNT2, RAB6A, RAB25, PITPNM3, RNF167, PGRMC1, RAB5A, RAB31, RAB32, RAB8B, RAB20, ARF1, TNFRSF17, RAB40B, RAB35, PARD3B, CHMP1A, CD274, RAB22A, RAB27B, TEX28, SLC2A10, STX17, SLC27A1, TMEM199, LZTR1, CHMP6, CNMD, RAB15, RAB30, LARS1, GRIP1, CDC42EP2, STX7, RAB3B, RAB14, STX1B, POGLUT3, PARD3, DOCK9, CDC42EP3, RAB23, PCSK6, RAB7A, RAB39A, LAPTM4A, SYTL3, CDC42EP4, TMCC1, JAK1, SSR4, CDC42EP1, RHEB, RAB11B, RUFY3, GDPD5, MS4A3, AGPAT3, NENF, STX16, PIP5K1B, SLC6A4, RAB28, MAL2, RAB40C, TMCC3, RAB26, SNAP47, RNF139, FIBP, GABARAP, LRPAP1, RAB6D, FRS2, CHP1, RNF145, PDCD1LG2, BCL2L14, MAP1LC3B, AGPAT4, SLC2A4, RAB4B, TSNARE1, RAB33B, LST1, MCF2L, RAB5B, POGLUT1, SIPA1, SLC50A1, DRD1, RAC3, RNF128, PITPNM2, RNF122, RAPGEF3, TR |
| endopeptidase Clp complex | cellular component | CLPX, CLPP |
| endoplasmic reticulum | cellular component | EGFR, HLA-DRB1, APOE, HLA-DPB1, TP53, CYP1A1, BCL2, CYP19A1, PTGS1, SRD5A2, PTGS2, CASP4, PLOD1, BAX, BAK1, MEST, HLA-B, HLA-DQB1, APOB, VWF, HLA-A, CYP17A1, CYP1A2, HMOX1, CYP2B6, FGFR3, KDR, HSD17B3, CIB1, SERPINA1, HLA-DRA, ALB, ITGA5, MGST1, CLU, HSD3B1, SRD5A1, HSD3B2, MTOR, PRDX4, BRSK2, PARK7, G6PC3, MAN1B1, HLA-DQA1, CAT, HSPA5, PDIA3, PTGDS, PGAP3, CD320, CYP21A2, GJA1, APEX1, AQP5, CYP1B1, CYP26B1, FLRT3, WFS1, CYB5A, NPC2, CATSPER3, BSCL2, RNASET2, ANXA5, HLA-C, PLA2G2A, PCMT1, DMPK, FATE1, NOX5, SCD, PJA2, SELENOF, USO1, ARL6IP5, CLDN14, TXNDC12, GLUD1, PRNP, ATP2A2, ALOX5AP, EEF1G, RPL5, ARCN1, EMD, LRBA, RAB9A, RPS3A, RPL27, RPS6, SEC11A, RPL24, REEP5, RPL6, LBR, EMC2, TRAM1, P3H3, GRAMD1C, GPC2, PIGX, FAM172A, UBXN4, RPL10L, MOGAT1, SELENOS, ADPGK, YIPF4, DERL2, ARV1, PNPLA8, ERAP1, DSE, RAB21, POMP, TMED5, ALG5, CEPT1, GET1, PGRMC2, CALU, ERLIN1, B3GALNT1, ATP10B, RPLP0, UGT2B7, PPIB, CANX, CYP2J2, TMEM50B, RPS8, RPS21, SLC35B1, SCAP, KEAP1, MLEC, MLC1, SEC23B, ERAP2, SLC30A9, LCLAT1, LACC1, D |
| endoplasmic reticulum chaperone complex | cellular component | HSPA5, PPIB, DNAJC10, P4HB, HSP90B1, SDF2L1, PDIA6, HYOU1, MZB1 |
| endoplasmic reticulum exit site | cellular component | TMED5, SEC23B, SAR1A, SEC31A, SEC16A, VAPB, TFG, SAR1B, VAPA, PDCD6, SEC23A, CTAGE8, CTAGE4, MIA3, PDCD6IP, YIPF5, CTAGE1, PLPP3, SEC31B, PREB, LRRK2, SEC16B |
| endoplasmic reticulum lumen | cellular component | F10, PTGS2, BGLAP, APOB, GAS6, GHRL, SERPINA1, F5, B2M, PLAUR, ADAMTS5, HSPA5, PDIA3, ARSA, SHH, RNASET2, CCN1, SELENOF, TXNDC12, COL11A1, ERAP1, CALU, COL5A2, LAMC1, PPIB, CANX, ERAP2, DNAJC10, FKBP14, DNAJB11, DBI, LTBP1, EDEM2, EDEM3, RCN1, PDGFB, PROC, P4HB, IGFBP1, HSP90B1, ITIH2, CES1, FBN1, COL9A3, KTN1, DNAJB9, SPP1, CTSC, COL12A1, PDGFD, EVA1A, SDF2L1, MGAT4A, FKBP7, COL3A1, COL4A1, F7, COL11A2, COL8A1, SDC2, MANF, WNT7B, MBTPS1, PDIA6, MYDGF, FKBP10, FGG, WNT4, COL7A1, GOLM1, SELENOM, QSOX1, COL2A1, PDIA4, WNT3A, APLP2, MFGE8, FSTL1, ARSH, TOR2A, COL23A1, FGF23, FSTL3, THBS1, COL4A2, ERO1A, LIPC, COL9A1, CKAP4, IGFBP7, FAM20C, COL26A1, ERP27, SPON1, MEN1, ARSB, ARSD, COL4A6, POGLUT3, P4HA3, IL27, SCG3, AMBN, MINPP1, PDGFA, BCHE, P4HA1, COL4A3, COL24A1, STC2, PRSS23, APOA1, COL1A2, ESD, PRKCSH, RCN2, ARSK, COL6A1, IGFBP4, PTPRN2, FUCA2, CFP, TGOLN2, H6PD, TNC, DNAJC3, MIA3, ERLEC1, ERP44, SIL1, TSPAN15, COLGALT2, COL21A1, SLC27A2, F8, SCG2, OS9, APOA5, TXNDC5, UGGT1, HYOU1, TOR1B, LAMB1, COL8A2, CERC |
| endoplasmic reticulum membrane | cellular component | EGFR, HLA-DRB1, HLA-DPB1, CYP1A1, BCL2, CYP19A1, PTGS1, SRD5A2, PTGS2, CASP4, FKBP4, PLOD1, BAX, MEST, FKBPL, HLA-DQB1, APOB, CYP17A1, CYP1A2, HMOX1, CYP2B6, HSD17B3, HLA-DRA, MGST1, HSD3B1, SRD5A1, HSD3B2, HSD17B2, MTOR, PLAUR, G6PC3, MAN1B1, HLA-DQA1, HSPA5, PTGDS, PGAP3, CYP21A2, GJA1, CDC42, CYP1B1, CYP26B1, FLRT3, WFS1, CYB5A, BSCL2, FKBP6, env, PLA2G2A, DMPK, NOX5, SCD, PJA2, ARL6IP5, AREG, ATP2A2, ALOX5AP, ARCN1, PITPNB, RAB9A, SEC11A, LBR, TRAM1, GRAMD1C, PIGX, UBXN4, MOGAT1, SELENOS, ADPGK, DERL2, ARV1, ALG2, RAB18, PNPLA8, ERAP1, RAB21, TMED5, ALG5, CEPT1, GET1, CALU, ERLIN1, ATP10B, UGT2B7, CANX, SRI, CYP2J2, TMEM50B, SLC35B1, SCAP, MLEC, SEC23B, ERAP2, LCLAT1, MBOAT2, RB1CC1, RAB2B, PAFAH2, AGPAT1, SEC22C, LMF2, FICD, TMEM106C, SEC11C, RNF26, B3GAT1, SERP1, TESPA1, FITM1, HACD1, FZD9, SURF4, ZW10, ATP8B3, TRIM13, SEC22B, ATP6AP2, CD74, ANXA7, KDELR2, UGT2B10, PIGA, CYP4A11, CYP4F3, ARL6IP1, EXT1, VMA21, ERMP1, ORMDL3, PDZD8, ZDHHC16, SARAF, RNF183, ALG14, POM121, RTN4, SLC35D1, USE1, SEC63, ARHGAP |
| endoplasmic reticulum quality control compartment | cellular component | MAN1B1, DERL2, CANX, TRIM13, EDEM2, EDEM3, ASGR2, RNF103, RHBDD1, SEL1L, RNF139, ERLEC1, FBXO6, RNF185, OS9, SYVN1, UGGT1, MARCHF6, EDEM1, CALR, AMFR, UGGT2 |
| endoplasmic reticulum Sec complex | cellular component | CFTR, SEC61B |
| endoplasmic reticulum tubular network | cellular component | REEP5, RAB18, RTN4, REEP1, RNF41, ATL1, PARP16, REEP4, REEP6, ATL3, PARP6, PARP8, RAB3GAP1, REEP3, LNPK, SPAST |
| endoplasmic reticulum tubular network membrane | cellular component | RTN4, ATL1, ATL3, ATL2, LNPK |
| endoplasmic reticulum-endosome membrane contact site | cellular component | STARD3NL, TMCC1, STARD3, MOSPD2 |
| endoplasmic reticulum-Golgi intermediate compartment | cellular component | HSPA5, FN1, DICER1, TMED5, SURF4, SEC22B, NUCB2, TRAPPC12, MTMR6, COPB1, LMAN2L, RAB6B, P4HB, STK17B, MCFD2, MGAT4A, PTPN2, PDIA6, MYDGF, LMAN1, LMAN2, IST1, TMED6, FTCD, STX17, CLN8, TMED2, DDHD2, HMGB1, MYO18A, TRIP11, YIF1B, COPG1, RGMB, CCDC115, TICAM2, CNIH4, TMED7, RER1, LRPAP1, TMED10, AZIN2, CHP1, ERP44, TRAPPC2, TRAPPC2B, GOLGB1, SCYL1, INPP5B, UGGT1, KDELR1, TMED4, TMED9, NAT8, GNPNAT1, COPG2, GBF1, YIF1A, MAN1A1, MGAT4B, ATP2A1, ANPEP, NUCB1, ERGIC1, CA4, RAB37, RAB1B, LMAN1L, SERPINH1, UGGT2, MGAT4D, TMED1 |
| endoplasmic reticulum-Golgi intermediate compartment membrane | cellular component | SERPINA1, F5, AREG, TMED5, SURF4, SEC22B, CD55, VMA21, TGFA, RAB2A, STX5, ERGIC2, CTSC, MCFD2, CNIH1, CD59, TAP1, LMAN1, COL7A1, LMAN2, TAP2, CNIH3, TBC1D20, STX17, TMEM199, GORASP1, CLN8, CSNK1D, TMED2, TRIP11, YIF1B, BET1, TAPBP, BCAP31, TMED7, GOSR2, TMED10, AZIN2, F8, STING1, KDELR1, TMED9, NAT8, ATP6AP1, SPPL3, CTSZ, PLPP3, CNIH2, YIF1A, ERGIC3, YKT6, PRRG4, INS, GRIA1, GOLGA2, ERGIC1, CALR, PIEZO1, ASPSCR1, RAB1B, DCSTAMP, LMAN1L, COPZ2, VMP1, ROBO1, FOLR1, TMED1 |
| endoplasmic reticulum-plasma membrane contact site | cellular component | GRAMD1C, SARAF, OSBPL5, STIMATE, SACM1L, ESYT2, GRAMD1A, C2CD2L, ESYT3, GRAMD1B |
| endosome | cellular component | EGFR, HLA-DRB1, HLA-DPB1, ACE, LHCGR, HLA-DQB1, CFTR, FLT1, KDR, ATP6V0A2, HLA-DRA, APP, ITGB1, HLA-DQA1, INSR, IGF2R, FPR1, CD68, NGF, CDH1, EZR, GJA1, CCR5, RAP1A, NTRK1, ANXA2, USP8, GALNTL5, PRF1, SNX3, VPS41, RAB9A, UBE2D3, ACAP2, RAB11FIP2, MARCHF3, STX12, SLC38A9, OPTN, AP5M1, ACKR4, TMEM9B, LAMTOR3, SCOC, RAB21, CHMP2A, TRAK2, ASTN2, VPS26A, IL15, SNX16, CXCR4, RAB11A, MTM1, MLC1, RABEP1, DOP1A, PHETA2, PARM1, EHBP1, ZNRF2, SPPL2A, RAB40A, SNX19, ITCH, TSG101, OSBPL1A, ARL8B, VPS29, ANKRD50, NOX1, UHRF1BP1L, DIAPH2, CD74, RAP2B, CCDC93, RABEPK, VPS52, RAB11FIP5, SPG21, CHMP5, VPS18, MAGEL2, VPS28, SNX6, ARHGAP32, SNX2, BDKRB2, RAB27A, RAB1A, BST2, WASHC5, ACAP1, AP1AR, LAPTM4B, WDFY1, MMGT1, NIPA2, DTX3L, SNX27, C9orf72, EPN3, TMEM165, VTA1, STX8, PIKFYVE, RAPGEF2, PLPP2, VPS4B, CD1C, ECE1, PLD1, TNFAIP1, CALCRL, GRIPAP1, WLS, WASHC2A, ENTHD1, ENTR1, STAMBPL1, ANKRD27, TM9SF2, SH3GL2, CHMP4A, AP5S1, MTMR4, VTI1B, CORO1C, INPP5F, WASHC3, SNX14, SNX10, ARPC5, TRIM3, SNX4, RAB4A, OCRL, VPS36, RAB11FIP4, |
| endosome lumen | cellular component | APOB, APP, PRLR, PRF1, JAK2, CD63, GH2, LRP2, AP4S1, LRPAP1, AP4M1, AP4B1, CSH1, INS, AP4E1 |
| endosome membrane | cellular component | EGFR, HLA-DRB1, HLA-DPB1, HLA-DQB1, APOB, ERBB2, ATP6V0A2, TLR4, HLA-DRA, TF, HLA-DQA1, INSR, CD68, CD320, USP8, SNX3, VPS41, UBE2D3, ACAP2, STX12, ANTXR1, LAMTOR3, TBK1, VPS26A, PARM1, ZNRF2, ITCH, TSG101, VPS29, RABEPK, VPS52, SPG21, CHMP5, VPS28, ARHGAP32, SNX2, LAPTM4B, APH1B, TMEM165, VTA1, PSENEN, PIKFYVE, LY96, MAP3K7, VPS4B, CD1C, IRAK1, RPS27A, TM9SF2, MYD88, CORO1C, SNX10, IRAK2, SCARB2, APH1A, AP3D1, TFRC, ANXA1, PMEPA1, LDLR, RAB5A, TAB1, SLC48A1, VPS45, UBAP1, RHOD, ATP6V0E1, ANTXR2, RAB35, CHMP1A, ANKFY1, RAB22A, HLA-DQA2, ADRB2, LAMP2, MRC1, IKBKE, NTRK2, CHMP6, AP1G2, CD63, RAB15, SPPL2B, DTNBP1, GGA3, FZD7, HLA-DOA, SLA2, NCDN, RAB23, RAB7A, SBF2, LEPROT, TMEM108, SLC9B2, COMMD1, STEAP2, TAB2, VPS37C, SLC6A4, CLCN3, CD164, ARHGAP1, BECN1, VPS53, GPR135, ATP6V0E2, AMN, OSBPL6, MYO1B, HLA-DPA1, CPTP, SCYL2, TICAM2, LITAF, NDFIP1, GPR61, ZDHHC11, NDFIP2, NSG2, TRAF6, TOM1L1, UBC, ABHD17B, SNF8, SORT1, UBA52, VAC14, WIPI1, TAB3, VPS37A, SORL1, VPS37B, LAMP1, SLC11A1, ATP6V0D1, APPL2, TPCN2, TMBIM |
| endosome to plasma membrane transport vesicle | cellular component | RAB6A, PICALM |
| endothelial microparticle | cellular component | ANXA5, ENG |
| epidermal lamellar body | cellular component | SPINK5, ABCA12, KLK5, KLK7 |
| epididymosome | cellular component | PPFIA3 |
| epsilon DNA polymerase complex | cellular component | POLE3, POLE4, CHRAC1, POLE |
| equatorial microtubule organizing center | cellular component | TUBGCP4, TUBGCP3, TUBGCP5, TUBGCP2, TUBGCP6 |
| ER membrane protein complex | cellular component | EMC2, EMC7, EMC3, EMC10, EMC4, MMGT1, EMC6, EMC8, EMC9 |
| ER to Golgi transport vesicle | cellular component | SERPINA1, APP, F5, TMED5, SEC31A, YIPF6, LMAN2L, ERGIC2, CTSC, LMAN1, COL7A1, LMAN2, KLHL12, TMED6, STX17, TMED2, TEX261, DDHD2, YIF1B, VANGL2, SEC24B, SEC23A, TICAM2, KLHL21, TMED7, TMED10, YIPF5, IER3IP1, F8, TMED4, TMED9, CTSZ, YIF1A, ERGIC3, GOLGA2, PCSK9, ERGIC1, LMAN1L, TMED1 |
| ER to Golgi transport vesicle membrane | cellular component | HLA-DRB1, HLA-DPB1, HLA-B, HLA-DQB1, HLA-A, HLA-E, HLA-DRA, B2M, HLA-DQA1, HLA-G, HLA-C, USO1, AREG, SCAP, SEC23B, SEC22B, CD74, VMA21, SEC31A, SREBF2, SEC16A, TGFA, SEC24C, SEC13, STX5, VTI1B, MCFD2, CNIH1, CD59, LMAN1, CNIH3, HLA-DQA2, STX17, SAR1B, TMED2, PDCD6, SEC24B, SEC23A, HLA-DPA1, TMED7, GOSR2, SEC24D, TMED10, SREBF1, VTI1A, CNIH2, SEC31B, GRIA1, PEF1, SEC24A, HLA-F, SEC16B, FOLR1 |
| ER ubiquitin ligase complex | cellular component | MARCHF6 |
| ERBB3:ERBB2 complex | cellular component | ERBB3 |
| ERCC4-ERCC1 complex | cellular component | ERCC1, SLX4, ERCC4 |
| eRF1 methyltransferase complex | cellular component | N6AMT1 |
| ESC/E(Z) complex | cellular component | EZH2, EED, PHF1, RBBP7, HDAC2, TRIM37, SUZ12, JARID2, RBBP4, MTF2, AEBP2 |
| ESCRT I complex | cellular component | TSG101, VPS28, UBAP1, VPS37C, VPS37A, VPS37B, MVB12A, MVB12B |
| ESCRT II complex | cellular component | VPS36, SNF8, VPS25 |
| ESCRT III complex | cellular component | CHMP2A, CHMP4A, CHMP4B, CHMP1A, CHMP6, CHMP4C, CHMP7, CHMP3, CHMP1B |
| ESCRT-0 complex | cellular component | HGS, STAM, STAM2 |
| euchromatin | cellular component | CBX2, ANKRD2, UHRF1, RRP1B, DNTT, RNF2 |
| eukaryotic 43S preinitiation complex | cellular component | EIF3H, EIF3E, EIF3D, EIF3K, EIF3L, EIF3F, EIF3M, EIF1, EIF3G, EIF3J, EIF3A, EIF3B, DHX29, EIF3C, EIF1B, EIF3I |
| eukaryotic 48S preinitiation complex | cellular component | EIF3H, EIF3E, EIF3D, EIF3K, EIF3L, EIF3F, EIF3M, EIF3G, EIF3J, EIF3A, EIF3B, EIF3C, EIF2S1, EIF3I |
| eukaryotic 80S initiation complex | cellular component | RPL38 |
| eukaryotic translation elongation factor 1 complex | cellular component | EEF1A1, EEF1D, EEF1A2, EEF1B2 |
| eukaryotic translation initiation factor 2 complex | cellular component | EIF2S2, EIF2A, EIF2S3, EIF2S1 |
| eukaryotic translation initiation factor 2B complex | cellular component | EIF2B3, EIF2B1, EIF2S1, EIF2B2, EIF2B5, EIF2B4 |
| eukaryotic translation initiation factor 3 complex | cellular component | EIF3H, EIF3E, COPS5, DDX3X, EIF3D, EIF3K, EIF3L, EIF3F, EIF3M, EIF3G, EIF3J, EIF3A, EIF3B, EIF3C, EIF3I |
| eukaryotic translation initiation factor 3 complex, eIF3e | cellular component | EIF3E, EIF3A |
| eukaryotic translation initiation factor 3 complex, eIF3m | cellular component | EIF3H, EIF3D, EIF3F, EIF3M, EIF3A, EIF3B, EIF3I |
| eukaryotic translation initiation factor 4F complex | cellular component | EIF4G2, EIF4A2, EIF4A1, EIF4E, EIF4E2, EIF4B, EIF4E3, EIF4H |
| excitatory synapse | cellular component | FGFR2, PALLD, BAIAP2, GRIN1, NLGN4X, LRRTM1, CACNG3, SRPX2, SYT1, DGKI, SYP, BSN, SLC17A6, GRIA2, PDE4B, ADCY8, CYFIP1, DLG4, LRRC4, SYNDIG1, AKAP5, LRRTM2, ELFN1, ITGA3, GRIA1, SHANK1, NETO1, SLC17A7 |
| exocyst | cellular component | MYRIP, SEPTIN2, EXOC6B, STXBP6, EXOC6, EXOC3, EXOC5, EXOC8, EXOC4, EXOC1, EXOC3L2, TNFAIP2, EXOC7, SH3BP1, EXOC2, EXOC3L1 |
| exocytic vesicle | cellular component | IGF1, RAB27A, SYT13, DPYSL3, SYTL4, SYT1, SYT5, SYT12, SYTL3, ANXA13, SYTL2, PI4K2A, SYT17, UNC13D, SYT6, SYT9, SYTL1, NKD2, SYT7, SYT2, SYT3, SYT15, SYT10 |
| exon-exon junction complex | cellular component | UPF2, R3HCC1L, TDRD3, SAP18, UPF3A, CASC3, UPF1, ACIN1, PYM1, RBM8A, SMG6, ALYREF, PNN, R3HCC1, MAGOHB, UPF3B, THRAP3, EIF4A3 |
| exosome (RNase complex) | cellular component | EXOSC10, MTREX, EXOSC9, ZFC3H1, MPHOSPH6, EXOSC7, EXOSC5, EXOSC1, EXOSC3, C1D, EXOSC8, DIS3, EXOSC4, ZFP36, DIS3L, EXOSC6, EXOSC2, DIS3L2, KHSRP |
| external side of apical plasma membrane | cellular component | SLC38A1, ABCC4, ABCG2 |
| external side of plasma membrane | cellular component | TNF, IFNG, IL4, IL6, ICAM1, ACE, HLA-DRB1, FAS, IL6ST, FASLG, TLR4, SEMA7A, GSR, ITGB1, ITGA5, B2M, TGFBR3, HFE, IL2RA, SERPINA5, ITGAV, KIT, CD79A, ITGA6, NRG1, CD69, PDCD1, IL17A, FCGR3A, NCAM1, CD9, CCR5, FGF8, CD8A, ANXA5, SPA17, IL13RA2, ANTXR1, ACKR4, ITGAE, CXCR4, ATP6AP2, CD74, CCR1, CTSK, CD83, CAPN2, VCAM1, CD79B, CLEC14A, CSF3R, LY75, CTSV, P4HB, CTSB, ITGA2B, IL1R1, CD1C, ECE1, XCR1, BCAM, CD226, LY6G6C, TFRC, THBD, CD34, BMPR1A, IL12RB1, ENOX1, LDLR, FGG, IDE, IL13, ENPP3, CTLA4, S1PR1, CNTFR, FCGR2B, ABCG1, ANTXR2, IL13RA1, MFGE8, AMOT, GPIHBP1, CD274, CLEC2D, LY6G6D, CLPTM1, THBS1, ITGAM, CXCR5, CD86, MOG, CD209, DMBT1, BTN3A1, ACKR3, TNFRSF9, IL23R, SSC4D, NRCAM, P2RY12, CRLF2, FGB, PTPRC, SELP, ITGA2, ITGB6, CXCR2, TNFRSF4, SCNN1G, CCR6, ADGRA3, LY6G5B, CD3E, LIFR, DNAI2, IGLL5, FLOT1, CD3G, GRIA2, BTN3A2, LRP2, GHR, CLCN3, MICB, RAET1E, IL7R, MAP3K5, B4GALT1, CX3CR1, ALCAM, BTNL9, MR1, ADAM30, HHLA2, ADA, MS4A1, IL1RL1, PDCD1LG2, CCRL2, BTN3A3, CRLF1, CD2, LAMP1, SLC2A4, CXCR3, CD200R1, TNFR |
| extracellular exosome | cellular component | SOD1, SERPINC1, TIMP1, EGF, FSHB, LHB, IL1B, HLA-DRB1, APOE, SHBG, ICAM1, ACE, MMP9, CD44, IL1RN, PTGS1, FAS, IGFALS, IL6ST, TNFSF10, GNAS, FKBP4, PLOD1, BAX, IL18, MEST, BCL2L2, NDRG2, IGF2, HLA-B, APOB, SOD2, VWF, SERPINE1, CDK1, HSP90AA1, ABCB1, MTHFD1, CFTR, HLA-E, PON1, MAPK3, MAPK1, TYK2, HLA-A, AXL, HSPA4, FASLG, GAS6, CIB1, CHD2, GSR, SERPINA1, C3, HLA-DRA, CRP, ALB, TF, KRT1, GAPDH, HSPB1, APP, ITGB1, ENO1, HEXA, GPX1, KLK3, CTSD, HEXB, VIM, GSTP1, CLU, PRPS2, F3, ACAT1, GSTT1, ABCC1, CTNNB1, GPX4, HSPA9, AKR1C3, AFM, VDAC2, HSPA2, LYZ, B2M, GNAI1, CSNK2B, TGFBR3, PLAUR, PRDX4, CLCA4, DECR1, PARK7, GDF15, GSTK1, A2M, LTF, CAT, SEMG1, AMY2A, SERPINA5, INSR, ITGAV, PGK2, YES1, HSPA5, IGF2R, PABPC1, SRC, ITGA4, MIF, CD46, MUC1, LPO, PDIA3, PTGDS, DPP6, ARHGDIA, POLG, CACNA2D1, GFRA1, SLC7A5, ASAH1, PABPC1L, TXNDC8, APOA1BP, PABPC3, MUC13, MUC5B, CD320, TAC3, SLC6A14, PDXK, CLDN11, IDH1, PLAU, PLAT, FN1, LDHC, FCGR3A, MMP7, HSPD1, THRB, G6PD, PCNA, CDH1, NCAM1, KRT10, ARSA, EZR, H2AFX, GJA1, CD9, COMT, A |
| extracellular matrix | cellular component | SOD1, TIMP1, APOE, DCN, MMP2, TGFB3, MMP9, VWF, SERPINE1, HSP90AA1, FGFR2, KRT1, CTSD, CLU, F3, BMP7, ADAMTS1, ADAMTS5, MMP12, PLAT, FN1, MMP7, ADAMTS20, LGALS3BP, ANXA2, ECM1, SLPI, CCN1, COL11A1, CCN2, LTBP2, HPSE, COL5A2, LAMC1, NDP, CCBE1, TNN, TNXB, LTBP1, NYX, TNFRSF11B, CCN6, FBN2, ELFN2, FLRT1, FBN1, COL9A3, POMZP3, CHAD, COL3A1, COL4A1, COL11A2, COL8A1, TIMP3, MFAP5, RELL2, LRRC3B, ASPN, MATN2, CHI3L1, WNT4, COLEC12, FBN3, LRRTM1, SPOCK2, BCAN, ADAMTS9, COL2A1, MMP15, LINGO4, COL23A1, HPSE2, SERAC1, MMP28, FBLN5, FLRT2, MMP23B, THBS1, COL4A2, LAMC2, OMD, DMBT1, ACAN, COL9A1, FBLN1, PRELP, POSTN, HAPLN4, NAV2, COL26A1, IMPG2, SPON1, COL4A6, LINGO2, BGN, MMP16, GPLD1, COL4A3, COL24A1, ABI3BP, LRRTM4, PHOSPHO1, ECM2, COL1A2, HAPLN1, LOX, LRRC32, GFOD2, THSD4, TECTA, COL6A1, MMP14, GLG1, COL6A6, MMP20, TNC, TGFBI, ADAMTS2, PI3, MUC4, MMP25, LRRC17, KAZALD1, HAPLN3, EMILIN1, WNT11, VTN, COL8A2, MMP13, CCN3, MMP21, HAPLN2, CRISPLD2, LRRN2, COL6A2, COL5A1, NID2, HSD17B12, EGFLAM, COL27A1, TIMP4, SMOC2, MATN |
| extracellular membrane-bounded organelle | cellular component | PHOSPHO1, ALPL |
| extracellular region | cellular component | GNAS, SOD1, EGFR, F10, SERPINC1, TIMP1, EGF, TGFB1, CGA, FSHB, LHB, TNF, IFNG, IL1B, APOE, AMH, SHBG, IL4, IL6, DCN, MMP2, INHBA, IL6R, CXCL8, TGFB3, ACE, MMP9, LIF, VEGFA, IL1RN, TNFRSF1A, TNFRSF1B, IL11, KITLG, IL10, ANOS1, BDNF, FAS, IL12A, CASP1, ADM, IGFALS, IL6ST, CASP4, TNFSF10, INSL3, IL18, ESR2, IL23A, IGF2, IFNA1, BGLAP, APOB, VWF, SERPINE1, HSP90AA1, FLT1, FGFR2, FGFR3, PON1, KDR, FASLG, TFPI2, S100A12, GAS6, NODAL, GHRL, GNRH2, SERPINA1, C3, GNRH1, PRL, IL1A, CRP, ALB, TF, APP, KLK3, CTSD, MSMB, PAEP, CGB3, CLU, FGFR1, F5, F3, PRLR, BMP7, TRH, LEP, AFM, LEPR, IFNAR2, PGF, PTEN, LYZ, B2M, TMSB4X, TGFBR3, PLAUR, PRDX4, SEMA3A, CLCA4, PON2, IGSF1, GDF15, ADAMTS1, ADAMTS5, GDF9, BMP15, A2M, GH1, LTF, SEMG1, AMY2A, IGF1, IL5, SERPINA5, ACR, BMP4, CCL5, MIF, HGF, MUC1, LPO, MMP12, PTGDS, XDH, IL2, NRG1, C1QBP, IL17A, APOA1BP, MUC13, IL21, MUC5B, TAC3, INSL6, FGF17, EPPIN, PLAU, PLAT, NGF, FN1, FCGR3A, MMP7, CDH1, NCAM1, F2R, CRISP1, FGF8, EDDM3B, ADAMTS20, SEMG2, BSPH1, LGALS3BP, EDDM3A, SHH, SPACA3, DE |
| extracellular space | cellular component | SOD1, EGFR, SERPINC1, TIMP1, EGF, TGFB1, TNF, IFNG, IL1B, APOE, AMH, IL4, IL6, ICAM1, DCN, MMP2, INHBA, IL6R, CXCL8, TGFB3, ACE, MMP9, LIF, VEGFA, IL1RN, TNFRSF1A, IL11, KITLG, IL10, ANOS1, FAS, IL12A, ADM, IGFALS, IL6ST, TNFSF10, INSL3, IL18, CMTM2, IL23A, IGF2, IFNA1, BGLAP, APOB, SERPINE1, HMOX1, FLT1, PON1, AXL, FASLG, DLK1, GAS6, NODAL, GHRL, SEMA7A, SERPINA1, C3, GNRH1, IL1A, CRP, ALB, TF, KRT1, HSPB1, APP, ENO1, KLK3, CTSD, MSMB, GSTP1, CLU, F5, F3, BMP7, LEP, AFM, IFNAR2, PGF, LYZ, B2M, TGFBR3, PRDX4, SEMA3A, HFE, GDF15, ADAMTS5, GDF9, BMP15, A2M, GH1, LTF, CAT, SEMG1, AMY2A, IGF1, IL5, SERPINA5, KIT, IGF2R, BMP4, CCL5, MIF, HGF, MUC1, LPO, PTGDS, XDH, IL2, NRG1, C1QBP, ASAH1, BMPR2, IL17A, APOA1BP, MUC13, IL21, MUC5B, TAC3, FGF17, EPPIN, PLAU, PLAT, FN1, MMP7, HSPD1, KRT10, EZR, CD9, CRISP1, FGF8, ADAMTS20, ACTB, SEMG2, LGALS3BP, EDDM3A, SHH, FLRT3, PLA2G6, OXT, INHA, ANXA2, ELANE, PIP, ACPP, CRISP2, AZGP1, LCN1, FGF9, PRDX1, DDR1, KISS1, ECM1, DSCAML1, LRRC4C, RNASET2, MAN2B1, IL33, CA2, SPINK1, SER |
| extracellular vesicle | cellular component | APOE, F5, MAN1B1, CD9, PCMT1, SLC12A2, GNAI2, GPM6A, ARRDC4, COL12A1, TFRC, GNB1, HEXD, PKM, TUBB2A, SLC39A12, MFGE8, PRELP, FGB, CBR1, ATP1A3, APOA1, ATP1A2, TUBB4B, CTSF, SDCBP, EDIL3, VCL, CLTC, DNAJC3, ATP2B3, PDCD6IP, SPTAN1, ATP1B1, ITGB2, COL6A2, ARRDC1, FGA, ATP1A1, COL6A3, EFEMP2, FBLN2, LFNG, SLC5A5, IFT172, OGN, RBP3 |
| extrinsic component of autophagosome membrane | cellular component | ULK1, WDFY3 |
| extrinsic component of cytoplasmic side of plasma membrane | cellular component | TYK2, YES1, SRC, ATP2A2, KCNAB1, FERMT2, IQGAP1, CYTH3, ERRFI1, KRAS, S100A6, DTNA, OSBPL2, SNX5, SRMS, PLEKHA4, CAV2, SNX9, SNAP25, TIAM1, SYAP1, CYLD, FARP1, TNK1, ESYT2, FER, LYN, GRAMD2A, RGS1, GRAMD1A, DLG4, MCF2L, FGR, KCNIP1, SLA, STAC2, ESYT1, HCK, SNX18, LCK, ESYT3, FRK, KCNAB2, STAC3, FES, PTK6, CARMIL2, RGS8, TGM3, PTK2B, CYTH1, MYZAP, BLK |
| extrinsic component of endoplasmic reticulum membrane | cellular component | ZC3H12A, OTULINL, CCDC115, GBA2, PML, DNAJB2 |
| extrinsic component of endosome membrane | cellular component | USP8, SNX16, SNX10, ANXA1, WDR91, SNX5, WDR81 |
| extrinsic component of external side of plasma membrane | cellular component | TF, ANXA1, FCN1, PLG, PCSK9, CUBN |
| extrinsic component of Golgi membrane | cellular component | GBA2, NUCB1, HID1 |
| extrinsic component of lysosome membrane | cellular component | RAB7A |
| extrinsic component of membrane | cellular component | PLAUR, GFRA1, EZR, NF2, MUC16, PRNP, RB1CC1, BCL2L11, ANXA1, SYTL4, VPS13C, CNTFR, HPCA, SNX33, DMBT1, UMOD, DEFB1, PACSIN2, MITD1, TAMM41, GML, WDR45, ATG2B, UBXN6, NCF1, VPS13D, WIPI2, ANXA13, BECN1, SEC23A, WDR45B, GBA2, RNF40, NMT1, WDFY3, EFCAB7, TPR, RGS6, WIPI1, BLOC1S6, NAAA, MTMR3, EHD2, AP4B1, MAL, FOLR3, BST1, RPH3A, AZU1, SYT6, GFRA3, ALOX15B, GFRA2, ATG2A, MICALL1, MGLL, ASPSCR1, NMT2, ATG13 |
| extrinsic component of mitochondrial inner membrane | cellular component | COQ8A, ATP23, NDUFAF5, COQ8B, COQ3, DUSP21, OPA1, TAMM41, COQ5, PAM16, COQ7, COQ6, NOA1 |
| extrinsic component of mitochondrial outer membrane | cellular component | SOX10, SARM1 |
| extrinsic component of neuronal dense core vesicle membrane | cellular component | KIF1A |
| extrinsic component of omegasome membrane | cellular component | ZFYVE1, ULK1 |
| extrinsic component of organelle membrane | cellular component | TEPSIN |
| extrinsic component of phagophore assembly site membrane | cellular component | ULK1 |
| extrinsic component of plasma membrane | cellular component | FMR1, ENO1, ANXA2, USP8, TDGF1, EPN3, NUMB, MFGE8, STOML2, SYTL3, AAK1, PPP3CA, NUMA1, EEA1, SYTL2, SCUBE1, PLG, S100A10, SYTL1, ST14 |
| extrinsic component of postsynaptic density membrane | cellular component | DGKI, SCRIB, CNKSR2, TIAM1, AKAP9 |
| extrinsic component of postsynaptic early endosome membrane | cellular component | GRIPAP1 |
| extrinsic component of postsynaptic endosome membrane | cellular component | PSD |
| extrinsic component of postsynaptic membrane | cellular component | CTNNA2, CRKL |
| extrinsic component of postsynaptic specialization membrane | cellular component | KPNA2 |
| extrinsic component of presynaptic active zone membrane | cellular component | DGKI |
| extrinsic component of presynaptic endocytic zone membrane | cellular component | PICALM, SNAP91 |
| extrinsic component of presynaptic membrane | cellular component | CTNNA2, STXBP5 |
| extrinsic component of synaptic membrane | cellular component | OLFM2 |
| extrinsic component of synaptic vesicle membrane | cellular component | ATP6V1B1, SGTA, SYN1, DOC2A |
| extrinsic component of vacuolar membrane | cellular component | VAC14 |
| F-actin capping protein complex | cellular component | CAPZA3, CAPZA1, ADD2, CAPZA2, CAPZB, CAPG, ADD1 |
| FACT complex | cellular component | SUPT16H, MMS22L, SSRP1, TONSL |
| FANCM-MHF complex | cellular component | CENPX, CENPS |
| Fanconi anaemia nuclear complex | cellular component | FANCA, FAAP24, FANCF, FAAP20, FANCL, FANCG, CORT, CENPX, FANCC, CENPS, FAAP100, FANCE |
| FAR/SIN/STRIPAK complex | cellular component | STRN, STRN3, STRN4 |
| fascia adherens | cellular component | CTNNB1, GJA1, DES, CTNNA3, NRAP, DSP, ACTN1, VCL, JUP |
| Fc-epsilon receptor I complex | cellular component | LILRA4, FCER1G, MS4A2 |
| female pronucleus | cellular component | CCNA2, CBX1, AKAP8, TET3, RIF1, STPG4 |
| FHF complex | cellular component | AKTIP, HOOK3, HOOK2, FAM160A2 |
| fibrillar center | cellular component | SUMO1, USO1, MLLT1, E2F5, CDCA7L, PLRG1, DKC1, COIL, POLR2F, EIF3L, NOP58, DUSP11, TXNRD1, DDX46, PSPC1, BTBD10, DSN1, ARHGAP32, SMARCA5, RPP38, SP140, THAP1, SNRPB2, UBE2N, HERC4, JAZF1, HOXB5, FOXA1, DAB2, IMP4, POLR1E, APEX2, NFIB, UBD, LIPA, DCAF1, NFKBIE, RSAD2, NOP56, RNMT, UBTF, FHIT, ZNF415, NONO, TAF1C, YY1AP1, FOXJ2, DEAF1, MRPL23, UTP4, CD2BP2, NFIC, EEF1D, SMARCB1, STOX1, PAK6, TIMM13, PTPN13, HEATR1, SAMD4A, PAX5, FBL, EXOSC8, FAM111A, MRI1, NUFIP1, PEX14, SMUG1, FBLIM1, RREB1, CD2AP, ESRRA, TCOF1, RRS1, TRERF1, CILK1, ACACA, DCLRE1A, CHCHD1, MAP3K14, STN1, KLF6, TAX1BP3, AKNA, LEO1, RAI14, EN2, DDX11, IP6K2, CCDC137, WDR33, SELENBP1, CC2D1A, PRMT7, ANKRD1, NUAK1, AGER, NHEJ1, GAR1 |
| fibrillar collagen trimer | cellular component | COL27A1 |
| fibrinogen complex | cellular component | FN1, FGL1, FGG, THBS1, SERPINF2, FGB, FGL2, FGA |
| ficolin-1-rich granule lumen | cellular component | LTA4H, HSPA8, PSMB1, PSMC2, EEF1A1, ACTR10, DERA, CAB39, DDX3X, PSMA2, PSMA5, COTL1, PSMB7, GYG1, ACLY, PSMD6, PSMD14, CFD, PSMD7, HUWE1, CTSB, COMMD3, ARPC5, CSTB, TNFAIP6, ILF2, FTH1, GUSB, APEH, PGM1, SRP14, MNDA, PNP, PKM, EEF2, PSMC3, XRCC6, AGL, OSTF1, DBNL, ALDOA, HMGB1, ARSB, HBB, CCT8, CDK13, FGL2, CANT1, PSMD12, CDA, CAND1, GPI, GNS, YPEL5, PSMD2, KCMF1, FCN1, ALOX5, VCL, LRG1, ALAD, NME2, ACTR2, AMPD3, QPCT, PGM2, BIN2, CAPN1, CTSS, PYGL, PRG2, CRISPLD2, CALML5, PPIE, PSMD3, CTSZ, IMPDH2, JUP, HSPA6, IMPDH1, ALDOC, PFKL, GMFG, ACTR1B, PDAP1, MMTAG2, CTSH, HK3, GSDMD, MVP, PLEKHO2, PPIA, PSMD13, SERPINA1, HSPA1A, HSPA1B |
| ficolin-1-rich granule membrane | cellular component | SLC2A3, ATP6AP2, CD55, COPB1, ATAD3B, MGAM, SERPINB6, CD93, CD58, AP2A2, PRCP, CLEC4C, LAMP2, UBR4, TBC1D10C, DIAPH1, DSP, DSG1, VPS35L, RAC1, PTPRN2, DYNC1LI1, ARL8A, NFASC, LAMP1, ITGAX, SLC11A1, LAMTOR1, DOK3, ADGRE3, STBD1, ITGB2, TMEM179B, FCAR, FPR2, FCER1G, NCKAP1L, TCIRG1, CLEC4D, ADAM8, LILRA3, ATP6V0C, NBEAL2, TRPM2, ATP6V0A1 |
| filamentous actin | cellular component | TPM1, EHBP1, ARPC3, DUSP22, NCKAP1, DPYSL3, SPECC1L, JAM3, PDLIM1, PDLIM2, PKD2, MICAL3, MYO6, ESPN, ACTG1, CARMIL1, MICALCL, PDLIM5, CD2AP, LDB3, SMTN, PDLIM7, MYO3A, RAC3, PDLIM4, PDLIM3, MYO18B, MYO1C, MICAL2, APC2, KPTN, SMTNL2, MICALL2, EHBP1L1, MICALL1, SMTNL1 |
| filopodium | cellular component | ITGB1, EZR, CDC42, TWF1, ACPP, NF2, DYNC1H1, SHTN1, MTM1, BAIAP2, IQGAP2, FAT1, DMD, VCAM1, ADGRA2, PPP1R9B, VASP, SLC9A3R1, UTRN, GPM6A, UBE2Q1, ABI2, DNALI1, DEF6, LY6G6D, ACTC1, ACTN2, MYO6, RAPH1, FSCN3, UNC5C, RUFY3, TENM2, FARP1, MSN, SPATA13, MYO1B, VAMP7, CXADR, ABI1, B4GALT1, RDX, ENAH, EPHA4, ARL4C, NGDN, MYO10, FGD4, PPP1R9A, PODXL, LCP1, PDPN, MYO3A, PALM, TWF2, RAPGEF3, CDK5, DAG1, MYO1G, FSCN1, SRCIN1, IGF2BP1, TIAM2, VIL1, RIPOR2, ACTA2 |
| filopodium membrane | cellular component | ITGAV, NF2, ANTXR1, FZD9, DMD, VASP, UTRN, TBC1D10C, ITGB3, MYO10, ARF6, PDPN, PALM, SYNE2, TTYH1, ITGA3, GAP43 |
| filopodium tip | cellular component | FMR1, CIB1, ABITRAM, ABI2, FZD3, MYO5A, EPHB1, CYFIP1, ABI1, UBE2K, MYO10, MORN4, MYO3A, TTYH1, OSBPL3, AP2A1, VIL1 |
| Flemming body | cellular component | TSG101, CEP55, USP3, VPS4B, RALA, NUP62, KIF14, CCDC66, IST1, EXOC6, MICAL3, RAN, NTNG2, CNTRL, EXOC4, AGAP2, BIRC6, EXOC1, PDCD6IP, DCDC1, OR2A4, CAPG, IL16, ARF6, CHMP4C, KIF23, EXOC7, EXOC2 |
| flotillin complex | cellular component | CTNNB1, CDH1, CTNNA1, CORO1C, FLOT1, CBL, SLC6A3 |
| focal adhesion | cellular component | EGFR, ICAM1, CD44, LIG4, FLT1, FGFR3, MAPK3, MAPK1, ATP6V0A2, HSPB1, ITGB1, ITGA5, VIM, CTNNB1, HSPA9, B2M, PLAUR, CAT, ITGAV, YES1, HSPA5, IGF2R, PABPC1, ITGA4, CD99, CD46, ITGA6, PDIA3, PLAU, HSPA1A, HSPA1B, CDH1, EZR, GJA1, CD9, YWHAQ, ACTB, CDC42, TWF1, SPRY4, FLRT3, TADA1, ANXA6, ANXA5, HSPA8, RPL4, RPL3, RPL5, RPS10, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPL31, RPL6, PPFIA1, CORO1B, SORBS1, THSD1, MRC2, LAMTOR3, RAB21, JAK2, LPXN, RPLP0, NPM1, PPIB, ACTR3, RPS8, RPL7A, AKAP12, G3BP1, PALLD, FERMT2, PPP1R12A, ARPC3, PRKAR2A, RPL7, IQGAP1, RPS18, RPS13, RPL19, FAT1, CSRP2, TNS3, NCKAP1, SNAP23, CPNE3, SVIL, CAPN2, RPS9, PXN, GDI2, RPL37A, PTK7, ARHGEF7, TNS2, RHOU, TNS4, PEAK1, FLRT1, P4HB, ITGA2B, RALA, HSP90B1, RPS2, ITGB5, RPL9, CTNNA1, RPS19, RPS5, NUMB, VASP, CD81, RPL30, RPL38, PLEC, CNN2, CORO1C, ARPC5, FLNB, KRAS, PTPRA, RPS3, LAP3, ARL2, RPL13A, PTK2, NEXN, SCARB2, CNN3, DLC1, REXO2, ANXA1, RPLP1, RRAS, CD59, DAB2, FHL1, DCAF6, CSPG4, ZFYVE21, PDLIM1, ZNF185, TSPAN9, RPL8, TPM4, CTTN, FZD2, AJUBA, FE |
| G protein-coupled receptor dimeric complex | cellular component | GABBR1, GRM1 |
| G protein-coupled receptor heterodimeric complex | cellular component | GABBR1, GPR156 |
| G protein-coupled receptor homodimeric complex | cellular component | GRM1 |
| G-protein beta/gamma-subunit complex | cellular component | GNG7, GNGT1, GNG10, GNG4, GNG2, GNG3, GNG11, GNG5, GNG8, GNG12, GNGT2 |
| GABA receptor complex | cellular component | GABRB2, GABRA1 |
| GABA-A receptor complex | cellular component | GABRB1, GABRA2, GABRG2, GABRB3, GABRA5, GABRB2, GABRA4, GABRG1, GABRA1, GABRA3, GABRG3 |
| GABA-ergic synapse | cellular component | GABRB1, LRFN4, LRFN5, MDGA1, NPTN, KCND3, CDH10, CNTN5, CBLN4, LRRTM1, NLGN2, KCND2, CTBP2, CALB1, GABRG2, GABRB3, PHB2, ACAN, GABRA5, EFNA5, ADRA1A, SLITRK1, BSN, GABRB2, SLC6A11, GABRA4, GUCY1A1, FLOT1, CNR1, IQSEC3, CLCN3, CTBP1, ATP2B3, GABRD, SEPTIN11, DRD3, PTPRO, GABBR1, ERC2, SLITRK3, DRD1, CDH13, ABHD6, CLSTN1, ATP2B1, GABRR2, DAG1, GABRA1, CSPG5, GABRA3, SLITRK2, LRRTM2, DRD2, ATP2B2, IGSF9B, SYT7, SV2A, CLSTN3, SLC32A1, GABRG3, GAP43, C1QBP, SLC6A17 |
| GAIT complex | cellular component | GAPDH, EPRS1, SYNCRIP, RPL13A |
| gamma DNA polymerase complex | cellular component | POLG, POLG2 |
| gamma-catenin-TCF7L2 complex | cellular component | JUP |
| gamma-secretase complex | cellular component | APH1B, PSENEN, APH1A, PSEN1, TMED10 |
| gamma-tubulin complex | cellular component | BLOC1S2, TUBGCP4, RESF1, TUBGCP3, PDE4B, TUBG1, CEP290, CKAP5, TUBGCP5, TUBGCP2, TUBGCP6, TUBG2, MARK4, TOPORS |
| gamma-tubulin ring complex | cellular component | BRCA1, MZT2B, TUBGCP4, CDK5RAP2, MZT1, MZT2A, TUBGCP5, TUBGCP6 |
| gamma-tubulin small complex | cellular component | TUBGCP3, TUBGCP2 |
| gap junction | cellular component | GJA1, CALB2, GJC2, TJP1, GJD2, PANX3, SPECC1L, GJB1, PANX1, GJB3, GJB5, GJD4, GJA3, GJA5, CCN3, GJA4, GJB6, GJB4, SGSM3, GJD3, PANX2, GJC1, GJA9 |
| GARP complex | cellular component | VPS52, VPS53, VPS51, EIPR1 |
| GATOR1 complex | cellular component | NPRL2, RRAGA, DEPDC5, BMT2, SZT2, NPRL3 |
| Gemini of coiled bodies | cellular component | NPAT, GEMIN6, GEMIN5, DDX20, GEMIN4, ZPR1, GEMIN8, SMN1, HABP4, GEMIN7 |
| germinal vesicle | cellular component | STPG4, MARCKS |
| GET complex | cellular component | GET3 |
| GID complex | cellular component | ARMC8, MAEA, RMND5A, RMND5B |
| GINS complex | cellular component | GINS1, GINS2 |
| glial cell projection | cellular component | FMR1, PRLHR, SIRT2, GLUL, TMEM50A, SLC4A8, ABCA7 |
| glial cytoplasmic inclusion | cellular component | FBXO7 |
| glial limiting end-foot | cellular component | EIF2S1 |
| glomerular endothelium fenestra | cellular component | CD34 |
| glucosidase II complex | cellular component | PRKCSH |
| glutamate-cysteine ligase complex | cellular component | GCLC |
| glutamatergic synapse | cellular component | HSPA8, ARF4, P2RY4, LRFN4, PRRT2, LRFN5, ERBIN, JAK2, CANX, MYH10, KPNA2, RAB11A, GRM3, BAIAP2, FZD9, FXR1, DGKE, RNF19A, VPS18, WASF3, NPTN, NRG3, PPP2R2A, GRIN1, SEMA3F, PIN1, RTN4R, FZD4, STAU1, LGI1, HTR3A, NUMB, PURA, GRIPAP1, SH3GL2, LIN7C, CACNG2, DVL1, GIPC1, NOS1AP, EPHB2, GPM6A, STX3, GSG1L, CDH10, DGKB, AP3D1, CPLX1, CTNND1, PPFIA2, BCR, PPP3CB, PFN2, SLC1A2, PPP3CC, ABR, SH3GL3, PPP1R1B, EPS15, SPTBN1, LRRTM1, SYNPO, GHSR, BCAN, KCND2, CACNG3, SYT1, VAMP1, CTBP2, WNT3A, CACNG7, ARF1, DRP2, ARHGAP22, CTTNBP2, IL1RAP, HOMER2, DNM3, NTNG1, MYO5A, GPC6, DGKI, CALB1, YWHAZ, ACTC1, HPCA, RELA, SLITRK4, PHB2, DLGAP4, ACAN, ACTN2, NEDD4, EPHB1, EIF4EBP1, SCRIB, NRCAM, DTNBP1, PSD2, LRRC4B, CADPS, PACSIN2, GRIP1, CHRM3, ADRA1A, DGKZ, SLITRK1, BSN, SORCS3, SPTBN2, EIF4E, SNAP25, GUCY1A1, CNKSR2, NRP2, FLOT1, ITGB3, SRGN, CNR1, YWHAE, EPS8, DLG1, TIAM1, GRIN2C, NPTX1, SCN2A, AKAP9, CDKL5, ACTN1, ADCY8, CLCN3, RAC1, AP2B1, PPP3CA, CADPS2, TNIK, UNC13B, NCS1, GRIK3, GRIK5, SNAP47, ARHGEF2, NTNG2, ADAM22, LYN, |
| glutamyl-tRNA(Gln) amidotransferase complex | cellular component | QRSL1, GATB, GATC |
| glycerol-3-phosphate dehydrogenase complex | cellular component | GPD1L, GPD2 |
| glycine cleavage complex | cellular component | GLDC, GCSH |
| glycine-gated chloride channel complex | cellular component | GLRA3 |
| glycinergic synapse | cellular component | HSPA8, NLGN2, IQSEC3, GLRA1, SLC6A5, GLRA2 |
| glycocalyx | cellular component | DEFB126 |
| glycogen granule | cellular component | PPP1R3D, PPP1CB, FASN, PPP1R3B, PCYT1A |
| glycosylphosphatidylinositol-mannosyltransferase I complex | cellular component | PIGM |
| glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex | cellular component | PIGA, PIGH, PYURF, PIGP, DPM2, PIGQ, PIGY |
| GMP reductase complex | cellular component | GMPR2, GMPR |
| Golgi apparatus | cellular component | EGFR, HLA-DRB1, APOE, ESR1, HLA-DPB1, CD44, TNFRSF1A, PTGS1, NOS3, NDRG2, HLA-B, HLA-DQB1, BGLAP, APOB, HLA-A, FGFR2, FGFR3, XPA, MAPK3, MAPK1, KDR, CIB1, PLAGL1, TLR2, SERPINA1, HLA-DRA, ALB, APP, ITGA5, CLU, MTOR, B2M, MAN1B1, HLA-DQA1, CAT, YES1, CD46, FUT4, PTGDS, ATR, NCOA2, TXNDC8, LMTK2, PGAP3, RAF1, CDH1, GJA1, F2R, PPARG, IL17RD, SPATA16, SPRY4, PICK1, DNM1L, USP8, DYNLT1, PKD1, DYNC2H1, STARD9, HLA-C, GLB1, CCNA2, ST6GALNAC6, GOPC, ASAP2, PJA2, SIPA1L3, USO1, B4GALT2, PRNP, GALT, SLC35E2B, ARF4, AQP2, ARCN1, PITPNB, VPS41, LRBA, RAB9A, TTC3, SLC35A1, PWP1, TMEM241, AGBL4, CEP57, STX12, SEMA6D, OPTN, YIPF4, DPY30, SLC35B3, ARV1, ACBD3, RAB18, IFT57, SCOC, DSE, RAB21, TMED5, CEPT1, B4GAT1, CALU, B3GALNT1, KIF20A, ST6GAL1, IL15, TMEM50B, RAB11A, ASIC1, SCAP, DOP1A, GLT8D1, PHETA2, PARM1, PACS1, SRCAP, SLC30A5, PXYLP1, RAB2B, USP6NL, TMEM43, PDCD10, FHDC1, NDST4, SAR1A, B3GAT1, BAIAP2, AP3M1, ARFGEF1, GOLGA8A, FZD9, PIK3C2A, RAB29, SURF4, KIF1C, ATP8B3, TPST1, SEC22B, PSMG1, CD74, GLA, DBI, KDELR2, PPT1 |
| Golgi cis cisterna | cellular component | GOLGA8A, ATL1, TMEM59, XYLT1, GOLGA6B, GOLT1A, SMPD3, LLGL1, GOLGA8N, GOLGA8M, NECAB3, GOLGA2, GOLGA6A |
| Golgi cis cisterna membrane | cellular component | NSG2 |
| Golgi cisterna | cellular component | ACPP, RAB30, STX16, GOLPH3L, GOLPH3, GCNT1, SORL1, GOLGA5, RAB34 |
| Golgi cisterna membrane | cellular component | FUT4, ASAP2, B4GALT2, RAB21, ST6GAL1, GOLGA8A, CSGALNACT1, ARAP1, B4GALT4, GALNT2, GAL3ST3, PSENEN, FUT6, CHSY1, SCFD1, APH1A, B4GALT3, B3GALT6, FUT5, SAR1B, TMED2, UXS1, GOLGA6B, CHSY3, ST6GAL2, FUT8, MOB4, GOLGA8N, CANT1, GPR89A, GOLGA8M, GPR89B, BCAP31, GOLPH3L, GOLPH3, B4GALT6, HACE1, NSG2, B4GALT1, GALNT1, SORT1, PITPNM1, TMEM87A, B4GALT5, CHPF, GOLIM4, ST3GAL4, FUT7, COG3, NAGPA, FUT3, ABO, NSG1, NUCB1, GOLGA2, FUT2, B4GALNT3, B4GALNT4, INPP5E, ST3GAL1, GAL3ST2, ST3GAL2, GAL3ST4, CSGALNACT2, GOLGA6A |
| Golgi lumen | cellular component | F10, TGFB1, CGA, LHB, DCN, BGLAP, GAS6, MUC1, MUC13, MUC5B, NGF, MUC16, GPC2, MUC6, PDGFB, PROC, GPC5, BPNT2, F7, SDC2, WNT7B, DEFB103A, CSPG4, WNT4, BCAN, PROS1, SDC4, WNT3A, DEFA3, FGF23, GPC6, OMD, DEFB4A, UMOD, ACAN, PRELP, DEFB1, DEFA5, MUC21, MUC15, PDGFA, BGN, PCSK6, MMP16, MMP14, LRPAP1, MUC7, HSPG2, MUC4, RAB33B, GOLIM4, VTN, GPC4, DEFA4, DEFA1, HS3ST1, LALBA, SOD3, DAG1, GPC1, MUC17, PODXL2, ABCC5, CSPG5, FURIN, MMP11, GPC3, MUC12, AGRN, F2, INS, PPIL2, MUC20, WNT3, WNT6, WNT7A, NCAN, SDC3, SDC1, PROZ, WNT5B, KERA, OGN, MUCL1 |
| Golgi medial cisterna | cellular component | GOSR1, MAN2A1, YIPF6, TMEM59, B3GALT6, YIPF2, YIPF1, HID1, SLC10A7 |
| Golgi membrane | cellular component | EGFR, HLA-DRB1, HLA-DPB1, TNFRSF1A, NOS3, HLA-B, HLA-DQB1, HLA-A, HLA-E, SERPINA1, HLA-DRA, F5, MTOR, B2M, HLA-DQA1, HLA-G, PGAP3, NCAM1, GJA1, CDC42, IL17RD, PKD1, WASL, env, HLA-C, ST6GALNAC6, GOPC, PJA2, USO1, B4GALT2, AREG, ARCN1, PITPNB, RAB9A, SLC35A1, STX12, OPTN, SLC35B3, ACBD3, SCOC, DSE, RAB21, B4GAT1, B3GALNT1, ST6GAL1, TMEM50B, SCAP, SEC23B, DOP1A, PARM1, PXYLP1, RAB2B, PDCD10, NDST4, SAR1A, B3GAT1, ARFGEF1, SURF4, TPST1, SEC22B, CD74, CD55, KDELR2, MAP4K2, EXT1, SGMS2, COP1, CSGALNACT1, RAB11FIP5, CHST12, RXYLT1, GOLT1B, ARHGAP32, CYTH3, B4GALT4, FAM20B, SEC31A, GOSR1, COPB2, COPB1, COPZ1, RAB1A, B4GALNT1, GALNT2, SREBF2, MAN2A1, RHOU, MMGT1, CHPT1, YIPF6, LMAN2L, BLZF1, TMEM165, RAB6B, TMEM167B, PIKFYVE, SH3GLB1, SEC16A, KDELR3, STX10, VAPB, PDGFB, TGFA, ECE2, EEF1AKMT4-ECE2, NSF, SEC24C, SEC13, RAB2A, STX5, PLD1, CNGA2, RTN1, WLS, GOLGA7, CHSY1, LARGE2, SCFD1, SH3GL2, C12orf49, STK25, PPP6C, TRAPPC3, AP1G1, RTN3, TNKS, SNAPIN, CTSC, AP1S2, SCARB2, ZDHHC17, B3GALNT2, MCFD2, GOLGA1, PDGFD, BET1L, |
| Golgi stack | cellular component | USO1, GALNT2, NSF, GOLGA7, OCRL, MGAT4A, MBTPS1, ZFYVE1, RAB27B, RAB30, RAB14, NSFL1C, AKAP9, TMBIM4, TOM1L1, GOLGB1, CLN3, TRAPPC4, MGAT2, SULF1, GBF1, PLK3, LPCAT2, RAB34, MGAT4B, COG2, RASIP1, SULF2, MARCHF4, MARCHF9, CLIP3, MGAT4D, ARSL |
| Golgi to plasma membrane transport vesicle | cellular component | RAB3IP, RAB3IL1 |
| Golgi trans cisterna | cellular component | YIPF6, BET1L, TMEM59, BET1, B4GALT1, YIPF2, YIPF1, HID1 |
| Golgi transport complex | cellular component | DNAJC28, COG4, COG8, COG7, COG1, COG3, COG2 |
| Golgi-associated vesicle | cellular component | GNRH1, ACR, VPS41, COPB1, SCFD1, OCRL, MAP6D1, AP1G2, TYR, STK26, MAP6, CHIC2, NUCB1, LRRK2 |
| Golgi-associated vesicle lumen | cellular component | BACE1 |
| Golgi-associated vesicle membrane | cellular component | CFTR, GJA1, PKD1, GOPC, SPPL2A, CNGA2, ZDHHC17, SPPL2B, RHOQ, GPR89A, ZDHHC13, SPPL3, CSPG5, CNGB1, PI4KA, RHO |
| GPI-anchor transamidase complex | cellular component | PIGS, GPAA1, PIGK, PIGT, PIGU |
| granular component | cellular component | SURF6, FBL, CARF, CLEC3B, CDKN2AIP, RRP1B |
| granular vesicle | cellular component | AZIN2 |
| granulocyte macrophage colony-stimulating factor receptor complex | cellular component | CSF2RB |
| Grb2-EGFR complex | cellular component | GRB2 |
| Grb2-Sos complex | cellular component | KHDRBS1 |
| growing cell tip | cellular component | PI4K2A |
| growth cone | cellular component | FMR1, NDRG2, GSK3B, CIB1, APP, CLU, DICER1, ADCY10, KATNB1, TIMP2, SHTN1, NRSN1, PCDH9, MYH10, PALLD, HNRNPR, IQGAP1, FXR1, ALS2, ABITRAM, ADGRL1, MYH14, AUTS2, C9orf72, PPP1R9B, RTN4R, SNCA, DPYSL3, PCDHGB1, DVL1, ARPC5, UTRN, GPM6A, KLC1, STX3, SETX, CTNND1, TSC1, CTTN, LRRTM1, APBB2, STMN3, MYO5A, FRMD7, SIRT2, FEZ1, CPEB4, EXOC6, DTNBP1, SHANK2, PSEN1, PINK1, CRTAC1, MYO9A, CALM3, SNAP25, SLC2A13, FSCN3, EXOC3, UNC5C, CNR1, FXR2, MAP3K12, EPS8, CDK5R1, RUFY3, GDPD5, SYAP1, DOCK7, KIF20B, TENM2, ZPR1, ELAVL4, BASP1, CBL, CXADR, ABI1, DCTN2, EXOC8, DSCAM, COPA, USP9X, CDK5R2, TSHZ3, PPP1R9A, PTPRO, NGEF, DLG3, CYTH2, TRPC5, ERC2, RAC3, TWF2, PREX1, SSH1, COPG2, CTSZ, LRIG2, PSEN2, ARHGAP4, CDK5, PTPRS, SIGMAR1, THY1, NGFR, NRP1, ANG, ACAP3, APBB1, KIF21B, ITGA3, L1CAM, CBARP, WHRN, RASGRF1, CRMP1, FSCN1, GPRIN1, ATCAY, ORAI2, IGF2BP1, IGHMBP2, PTK2B, TIAM2, AMFR, MAP1B, HAP1, LRRK2, ZNF804A, NEFL |
| growth cone filopodium | cellular component | FMR1, APP, APBB1, ITGA3 |
| growth cone lamellipodium | cellular component | APP, PPP1R9A, APBB1 |
| growth cone leading edge | cellular component | ARPC3 |
| growth cone membrane | cellular component | TRPV2, EXOC4, NECTIN1, EXOC7, GAP43 |
| growth hormone receptor complex | cellular component | GHR |
| GTPase activator complex | cellular component | GNB5 |
| Gtr1-Gtr2 GTPase complex | cellular component | RRAGA, RRAGB, RRAGD |
| guanyl-nucleotide exchange factor complex | cellular component | RAP1A, RASGRP3, C9orf72, EIF2B3, DGKI, WDR41, ULK1, PDE3B, DOCK1, SMCR8, KNDC1, ELMO1 |
| guanylate cyclase complex, soluble | cellular component | GUCY1B1, GUCY1A1 |
| H zone | cellular component | DST, ATP2A1 |
| H4/H2A histone acetyltransferase complex | cellular component | MRGBP |
| haptoglobin-hemoglobin complex | cellular component | HBG2, HBD, HBB, HBZ, HP, HBQ1, HBA1 |
| HAUS complex | cellular component | HAUS2, HAUS4, HAUS5, HAUS6 |
| HCN channel complex | cellular component | HCN2, HCN1, HCN4 |
| hemidesmosome | cellular component | ITGB1, ITGA6, ERBIN, PLEC, DST, ITGB4, EPPK1, JUP, COL17A1 |
| hemoglobin complex | cellular component | AHSP, HBG2, HBD, HBB, HBZ, CYB5R3, HBQ1, HBA1 |
| heparanase complex | cellular component | HPSE |
| heterochromatin | cellular component | DNMT1, MBD2, SUMO1, CBX2, TCP1, ATRX, CBX8, ORC2, TASOR, WDR76, CBX6, PHC2, CHD5, SALL4, DDX6, MECP2, PML, TOP2B, UHRF1, ZBTB18, MBD3, SMARCAD1, RRP1B, SALL1, CBX5, MORC2, RNF2 |
| heteromeric SMAD protein complex | cellular component | SMAD2, SMAD3 |
| heterotrimeric G-protein complex | cellular component | GNAS, GNAO1, GNAI1, GNAI2, GNB3, GNB5, GNG7, GNAI3, GNB1, GNB4, GNAZ, GNAT2, GNAL, GNGT1, GNG10, GNA12, GNA11, GNG4, GNG2, GNAQ, GNG3, GNG11, GNG5, GNA14, GNG8, GNG12, GNA15, GNB2, GNG13, GNGT2 |
| HFE-transferrin receptor complex | cellular component | TF, B2M, HFE, TFRC, BMPR1A, HJV, TFR2 |
| high-density lipoprotein particle | cellular component | APOE, PON1, SAA1, SAA4, HDLBP, APOF, APOO, LIPC, SAA2, APOA1, APOC1, PLA2G7, APOA5, CETP, APOM, LCAT, APOL1, APOH |
| hinge region between urothelial plaques of apical plasma membrane | cellular component | MAL |
| hippocampal mossy fiber | cellular component | SLC4A8, MAP1B |
| hippocampal mossy fiber expansion | cellular component | TNN, MICAL1 |
| hippocampal mossy fiber to CA3 synapse | cellular component | RNF19A, SH3GL2, CACNG2, CTNND1, CTNNA2, AKAP7, SYT1, CALB1, YWHAZ, DTNBP1, SYT12, ADCY8, UNC13B, VAMP7, GRIK5, SNAP47, NECTIN1, EPHA7, EFNB3, GRIK4, SLC30A3, PRKAR1B, SLC6A9, BACE1, SYT9, LRRTM2, P2RX3, SYT7, SH3GL1, GRIK2, RAPGEF4, GPER1 |
| HIR complex | cellular component | HIRA |
| histone acetyltransferase complex | cellular component | KAT7, JADE3, MORF4L2, DPF1, MORF4L1, OGT, KANSL1L, RSF1, HCFC1, WDR5, CREBBP, MSL3, KANSL2, EP300, PHF10, KAT5, BRPF1, KANSL1, PHF20, MEAF6, KANSL3, MCRS1, KAT2A, KAT6A, KAT2B, ING5, DPF2, KAT6B, JADE2, ING4, BRPF3 |
| histone deacetylase complex | cellular component | NRIP1, MBD2, MTA2, HINT1, HDAC4, HDAC11, HDAC2, RERE, SIN3B, SAP18, HDAC9, MIDEAS, SAP30L, HDAC8, DNTTIP1, TAF6L, SAP30, NCOR2, ZNF217, HDAC7, HDAC3, TBL1X, NCOR1, TRERF1, ZNF541, HDAC6, MECOM, HDAC10, CBX5, HDAC5, PHF21A, SATB2 |
| histone H3-K14 acetyltransferase complex | cellular component | BRD1 |
| histone locus body | cellular component | ZC3H8, ICE2, ELL, ICE1 |
| histone methyltransferase complex | cellular component | DPY30, KDM5B, WDR82, ASH2L, CXXC1, NCOA6, RBBP5, KDM4A, HDAC9, WDR5, KDM4C, KDM4D, KMT2D, JARID2, ZNF335, MEN1, KMT2A, KMT2C, SETD1B, PAGR1, PRDM4, KDM4B, KDM5A, CBX5, SETD1A, KMT2B, PAXIP1 |
| histone pre-mRNA 3'end processing complex | cellular component | SYNCRIP, LSM11, YBX1, SNRPB, ERI1, SLBP |
| holo TFIIH complex | cellular component | ERCC2, GTF2H3, CDK7, CCNH, GTF2H1, GTF2H4, MMS19, MNAT1, GTF2H5 |
| HOPS complex | cellular component | VPS41, VPS18, AKTIP, VPS33B, HOOK3, VIPAS39, STX17, HOOK2, VPS16, VPS33A, VPS39 |
| host cell | cellular component | DYNLT1, NUP93, NUP37, NUP88, TSG101, NUP85, NUP107, NUP43, POM121, VPS28, NUP35, NUP58, XPO1, SEC13, RPS27A, NUP205, NUP50, NUP62, NUP155, UBAP1, NUP153, IFIT1, CD209, RAE1, SEH1L, RAN, NUP133, VPS37C, UBC, NUP54, TPR, RANBP2, NUP98, UBA52, VPS37A, VPS37B, MVB12A, AAAS, UBB, NUP210, MVB12B, NMT2, NUP188, NUP42, NUP214, NUP160 |
| host cell cytoplasm | cellular component | PF4 |
| host cell endosome | cellular component | env |
| host cell endosome membrane | cellular component | env |
| host cell membrane | cellular component | env |
| host cell mitochondrial intermembrane space | cellular component | SCO1 |
| host cell nucleus | cellular component | KPNA4, H1-4, CCNC, NR1D2, SIAH1, RNGTT, KPNA2, BAZ2B, ESRRG, HSF5, KPNA5, SIAH2, RARB, CCNH, HNF4G, SETDB2, CCNT1, PPARD, CCNJL, KPNA3, KPNA6, CREBBP, POLR1E, BACH1, CCNQ, MAFG, POLR1A, CCND1, MRTFA, HSFX1, RNMT, RELA, MAF, RAD17, H1-2, RORA, MAFF, NR2E3, NR2F6, ETS1, NR4A2, H1-8, FAM120C, CCNE1, NFKB2, REL, HSFY1, BACH2, RAD1, CCNK, POLR2E, MECP2, EP300, HP1BP3, SIAH3, NR1H4, MBD5, BAZ2A, FAM120B, CCNL2, NR2C1, EHF, MBD4, KPNA1, SETDB1, CNOT2, NXF1, H1-0, CCNL1, CENPB, ESRRA, NR1D1, MAFK, MBD3, H1-5, CCNF, HNF4A, NRL, GABPA, NFE2, NFE2L1, POLD4, ERG, H1-1, CNOT3, CCNE2, NR2F1, MYCL, H1-3, RXRG, NR4A3, KAT6A, FAM120A, RARG, CCNO, RELB, NR4A1, PPARA, HSF4, ETV7, THRA, RORC, ESRRB, NR3C2, CCND3, FLI1, ZC3HC1, KAT6B, SPDEF, ETS2, CCNB3, ESR1, RARA, NR2C2, NR1H2, H4-16 |
| host cell perinuclear region of cytoplasm | cellular component | LMAN1 |
| host cell plasma membrane | cellular component | env |
| host cell presynaptic membrane | cellular component | PI4K2A |
| host cell surface | cellular component | AXL |
| host cell viral assembly compartment | cellular component | BICD1 |
| Hrd1p ubiquitin ligase complex | cellular component | SEL1L, OS9, SYVN1 |
| Hrd1p ubiquitin ligase ERAD-L complex | cellular component | DERL2, DERL1, SEL1L2, SEL1L, RHBDD2, SYVN1, AUP1, DERL3 |
| HSP90-CDC37 chaperone complex | cellular component | CDC37 |
| HULC complex | cellular component | UBE2B, RNF20, UBE2U, RNF40 |
| hyaluranon cable | cellular component | HAS3 |
| I band | cellular component | CACNA1S, MTM1, FERMT2, TCAP, CRYAB, ANKRD2, RYR1, CFL2, ACTC1, TTN, ALDOA, MYPN, NEBL, KLHL40, KAT2B, ATP2A1, MYL3, CASQ1, BIN1, MYZAP, ANKRD1, SMTNL1, S100A1 |
| I-kappaB/NF-kappaB complex | cellular component | RELA, NFKBIA, NFKB2, REL, RELB |
| immunoglobulin complex, circulating | cellular component | IGLL5, IGLL1 |
| immunological synapse | cellular component | ICAM1, EZR, PTPRJ, NPTN, BCL10, SNX27, CD81, VAV3, GZMB, CD53, HAVCR2, STOML2, ZAP70, PRKCQ, SCRIB, STX7, SKAP1, CD3E, DLG1, FYB2, CD37, ALCAM, PDCD6IP, GZMA, SOCS6, CRTAM, DUSP3, ATP2B1, LAT, LCK, CD28, CD6, CORO1A, MYH9, RHOH, CARD11 |
| inactive sex chromosome | cellular component | HNRNPU |
| inclusion body | cellular component | HSPA1A, HSPA1B, PRNP, IAPP, KEAP1, SNCA, PSMC5, BAG5, AGL, SQSTM1, PSMC4, WDFY3, HDAC6, MT3, HTT, GYS1, DNAJB2, HAP1, LRRK2 |
| inflammasome complex | cellular component | CASP4, DDX3X, NLRP9, NLRP3, NLRP1, CARD8, DHX33, GSDMD |
| inhibin A complex | cellular component | INHBA, INHA |
| inhibin B complex | cellular component | INHA |
| inhibin-betaglycan-ActRII complex | cellular component | TGFBR3, INHA, ACVR2A |
| inhibitory synapse | cellular component | CEP112, NPTN, NLGN2, IGSF9, GAD1, LHFPL4, IQSEC3, GLRA1, MAF1, IGSF9B, SLC32A1, IGSF21, GAD2 |
| inner acrosomal membrane | cellular component | CD46, TMEM190, TRIP11, EQTN |
| inner dense plaque of desmosome | cellular component | VCL |
| inner dynein arm | cellular component | DNAH1, WDR63, DNAH3 |
| inner mitochondrial membrane protein complex | cellular component | DNAJC19 |
| Ino80 complex | cellular component | ACTL6A, RUVBL2, INO80C, INO80B, YY1AP1, NFRKB, YY1, RUVBL1, MCRS1, INO80E, UCHL5, TFPT, INO80, ACTR5 |
| insulin receptor complex | cellular component | INSR, IRS1, INSRR |
| insulin-like growth factor binary complex | cellular component | IGFBP6 |
| insulin-like growth factor binding protein complex | cellular component | IGF1, IGFBP5 |
| insulin-like growth factor ternary complex | cellular component | IGFALS, IGF1, IGFBP5 |
| insulin-responsive compartment | cellular component | RAB4A, MYO5A, DENND4C, SLC2A4, RAB4B, LRP1 |
| integral component of autophagosome membrane | cellular component | LAMP2, ENTPD4 |
| integral component of cytoplasmic side of endoplasmic reticulum membrane | cellular component | SPPL2A, PKD2, SPPL2B, HM13, SPPL3 |
| integral component of endoplasmic reticulum membrane | cellular component | G6PC3, HSPA5, WFS1, BSCL2, SCD, TRAM1, SELENOS, DERL2, SLC35B3, SLC35B1, FICD, FITM1, HACD1, ARL6IP1, EXT1, SGMS2, SARAF, RNF183, RTN4, SEC62, DERL1, DNAJB12, SPCS1, ZMPSTE24, XBP1, RTN1, ERGIC2, EMC6, BNIP1, DHRS9, ELOVL6, RETREG1, CREB3, TAP1, DGAT2, ELOVL4, DPAGT1, LRIT1, SLC27A5, TAP2, HSD11B1, TEX261, HACD2, SLC37A3, ELOVL2, ELOVL5, HACD3, TAPT1, ANKLE2, ACER3, TECR, ERN1, RHBDD1, ABCB9, RHBDD2, RRBP1, SLC37A4, ASPH, SAMD8, TBL2, SLC27A2, CLN3, PIGG, SYVN1, STING1, MARCHF6, SLC37A1, RCE1, TM7SF2, DPM2, FKBP8, NFE2L1, EDEM1, ESYT1, AUP1, ATF6B, BFAR, DHCR7, UBXN8, TMEM33, SEC61A1, ALG3, PIGT, ELOVL1, DOLK, ERGIC3, RTN2, CPT1C, ELOVL3, PREB, ERGIC1, DERL3, DCSTAMP, XXYLT1, AMFR, STIM1, SLC37A2, LNPK, EIF2AK3 |
| integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane | cellular component | STING1 |
| integral component of Golgi membrane | cellular component | SLC35A1, SLC35B3, B4GAT1, SLC35B1, TPST1, SGMS2, CSGALNACT1, CHST12, B4GALNT1, GALNT2, ERGIC2, BET1L, UBIAD1, SLC35A5, SLC35A3, QSOX1, LARGE1, TBC1D20, QSOX2, TEX261, A4GALT, MFNG, PCSK2, PCSK4, YIF1B, STEAP2, ACER3, BET1, TVP23B, ENTPD4, UNC50, SLC39A13, RER1, ZDHHC20, SLC35A4, SAMD8, IER3IP1, POMGNT1, CASD1, MAN1C1, FKTN, YIF1A, SLC35A2, ERGIC3, FURIN, LFNG, ERGIC1, MYMK, PCSK7, B4GALNT2, TVP23C, ACER2, CSGALNACT2 |
| integral component of lumenal side of endoplasmic reticulum membrane | cellular component | HLA-DRB1, HLA-DPB1, HLA-B, HLA-DQB1, HLA-A, HLA-E, HLA-DRA, HLA-DQA1, HLA-G, HLA-C, CANX, SPPL2A, CD74, HLA-DQA2, PKD2, SPPL2B, HM13, TAPBP, BCAP31, HLA-DPA1, SPPL3, CALR, HLA-F |
| integral component of lysosomal membrane | cellular component | SLC38A9, ATP13A2, NPC1 |
| integral component of membrane | cellular component | EGFR, EGF, TNF, HLA-DRB1, ESR1, HLA-DPB1, ICAM1, IL6R, BCL2, ACE, CD44, TNFRSF1A, TNFRSF1B, KITLG, LHCGR, FSHR, FAS, SRD5A2, IL6ST, TNFSF10, BAX, BAK1, AMHR2, MEST, CATSPER1, CMTM2, RXFP2, CATSPER2, HLA-B, HLA-DQB1, HLA-A, ERBB2, ABCB1, CFTR, HLA-E, FLT1, FGFR2, FGFR3, AXL, KDR, KIR2DL2, KIR2DS2, FASLG, DLK1, ADCY2, WDR11, ATP6V0A2, TLR4, TLR2, HLA-DRA, APP, ITGB1, ITGA5, MGST1, FGFR1, F3, HSD3B1, PRLR, SRD5A1, EDNRA, HSD3B2, GNRHR, ABCC1, HSD17B2, VDAC2, LEPR, IFNAR2, TGFBR3, PLAUR, CLCA4, HFE, IGSF1, G6PC3, IL1RAPL1, MAN1B1, RTL1, IL2RA, HLA-DQA1, INSR, ITGAV, IGF1R, KIT, IGF2R, CD79A, ITGA4, CD99, CD46, MUC1, HLA-G, FPR1, FUT4, ITGA6, CD68, DPP6, CACNA2D1, SLC7A5, NRG1, CD69, BMPR2, PDCD1, GPRC6A, DPY19L2, LMTK2, IZUMO1, PROKR2, KISS1R, SLC22A18, PGAP3, MUC13, SPACA1, KCNK9, CD320, SLC6A14, PCDH17, CLDN11, FCGR3A, CDH1, NCAM1, GJA1, CD9, COMT, F2R, TACR3, OXTR, CCR5, AQP5, TAS2R38, MCL1, COX10, CDH18, CT83, OR2W3, SPACA3, IL17RD, SLC13A3, KCNK17, SPATA9, CLEC7A, SLC6A20, KCNK4, FLRT3, SLC16A7, WFS1, SLC22A |
| integral component of mitochondrial inner membrane | cellular component | PPOX, COA1, MPC1, ETFDH, MPC2, SCO1, COX11, MPC1L, CCDC51, SFXN1, COX16, TMEM11, APOO, PET100, SMDT1, TIMM17B, SLC25A3, COX18, TIMM17A, MCUR1, SFXN3, L2HGDH, MCUB, TMEM177, OXA1L, SFXN2, PISD, SCO2, SFXN5, AGK, SLC25A19 |
| integral component of mitochondrial membrane | cellular component | SLC25A4, MFF, BID, CNR1, TMEM70, ABCB10, OXA1L, MICU1, SLC8B1 |
| integral component of mitochondrial outer membrane | cellular component | BAK1, DMPK, FUNDC1, MFF, CPT1A, FUNDC2, MFN1, PINK1, BNIP3, TOMM20, SPIRE1, FIS1, RHOT2, ARMCX3, RHOT1, ABCB6, MUL1, TOMM20L, TOMM40, SYNJ2BP, GDAP1 |
| integral component of neuronal dense core vesicle membrane | cellular component | SYT5 |
| integral component of nuclear inner membrane | cellular component | LBR, TMEM43, LEMD2, LEMD3, P2RX7, P2RX6, P2RX4, P2RX5, SUN2, P2RX3, TMEM201, P2RX2 |
| integral component of nuclear outer membrane | cellular component | SYNE4 |
| integral component of omegasome membrane | cellular component | EMC6 |
| integral component of organelle membrane | cellular component | WLS, RYR1, SLC66A1, TRABD2B, SLC22A17, VOPP1, RNF152, VAMP5, TRABD2A |
| integral component of peroxisomal membrane | cellular component | PEX10, PEX2, PEX11B, PEX26, PEX13, PEX12, PEX3, SLC25A17, FIS1, FAR1, PEX11G, SLC27A2, PEX11A, PEX16, FAR2, ABCD1 |
| integral component of plasma membrane | cellular component | TNF, ICAM1, CD44, TNFRSF1A, TNFRSF1B, LHCGR, FSHR, FAS, TNFSF10, AMHR2, HLA-B, HLA-A, FLT1, FGFR2, FGFR3, AXL, KDR, FASLG, ADCY2, TLR4, TLR2, HLA-DRA, APP, FGFR1, EDNRA, GNRHR, ABCC1, IFNAR2, TGFBR3, PLAUR, CLCA4, HFE, HLA-DQA1, INSR, ITGAV, IGF1R, IGF2R, CD79A, CD99, CD46, MUC1, CD52, SLC7A5, NRG1, CD69, BMPR2, PROKR2, KISS1R, KCNK9, SLC6A14, GJA1, CD9, F2R, TACR3, OXTR, CCR5, AQP5, IL17RD, SLC13A3, KCNK17, SLC6A20, KCNK4, FLRT3, SLC16A7, SLC22A5, NTRK1, PKD1, DDR1, ART3, SLC26A8, AQP7, CD8A, MAS1, SLC19A1, SLC6A8, PTPRJ, TNFRSF25, SEMA3E, SLC26A4, ATP2A2, GABRB1, SLC2A5, RYK, SLC26A3, AQP2, P2RY4, SLC35A1, KCNJ10, ROR1, SEMA6D, ASIC4, LPAR4, TSPAN10, PCDH9, ACKR4, PCDHB9, SIRPB1, LANCL1, SLC28A2, GPR137B, TNFSF15, SLC2A3, SLC25A4, CHRNA5, SLC6A6, ASIC1, GRM3, GRM4, MIGA1, SLC30A5, F2RL3, KCNH6, SLC28A1, SLC22A2, GP1BB, SLC6A2, CCR1, GPR183, CSF2RB, SLC12A2, OLR1, CD83, FAT1, SLC1A5, ASIC2, SYPL1, SLCO6A1, OR5AR1, SGMS2, LMBR1, SLC25A13, RXYLT1, SLC17A3, SLC16A5, ADGRL1, KCNK2, VCAM1, BDKRB2, ACVR1B, CD79B, |
| integral component of postsynaptic density membrane | cellular component | LRFN4, LRFN5, NPTN, GRIN1, CACNG2, GSG1L, CACNG3, CACNG7, LRFN2, NRCAM, LRRC4B, CHRM3, SLITRK1, SORCS3, DCC, SLC30A1, GRIK5, ADAM22, OPRD1, CACNG4, DRD3, PTPRO, PLPPR4, LRRC4, GRID2, SLITRK3, EFNB2, EPHA7, LRFN3, CLSTN1, PTPRS, EFNB3, CNIH2, CHRM1, GRIN2A, ADRA2C, LRRTM2, GRIA1, LRFN1, GRID1, CLSTN3, SHISA6, NETO1 |
| integral component of postsynaptic membrane | cellular component | CANX, GRM3, HTR3A, EPHB2, LRRTM1, NLGN2, KCND2, GABRA5, NRCAM, ADRA1A, SLC8A3, SLC6A11, NRP2, SLC6A4, SLC8A1, GRIK5, EPHA4, GABRD, GRM2, CHRNA6, CDH9, SLITRK3, DRD1, ABHD6, FXYD6, PCDH8, GRIK4, CHRM1, SLC6A9, KCNC1, NRP1, CSPG5, ADRA2C, PRRT1, SLITRK2, DRD2, KCNA3, KCNA1, ADORA2A, SLC6A3, DAGLA, CHRM2 |
| integral component of postsynaptic specialization membrane | cellular component | CHRNE, KCND3, CDH10, LRRTM1, NLGN2, KCND2, CHRNB1, GABRA5, CHRND, CHRNA10, GABRB2, GABRA4, P2RX6, GLRA1, SLITRK3, EPHA7, LRFN3, GABRA1, CHRNB2, GABRA3, HTR5A, LRRTM2, SHISA7, CHRNA1 |
| integral component of presynaptic active zone membrane | cellular component | P2RY4, CANX, NPTN, GPM6A, CDH10, P2RY1, NECTIN1, LRFN3, ATP2B1, CACNA1D |
| integral component of presynaptic membrane | cellular component | PRRT2, GRM3, HTR3A, EPHB2, APH1A, SLC1A2, NRXN1, GABRA5, CHRM3, ADRA1A, PSEN1, SLC6A11, CNR1, SCN2A, SLC6A4, ADCY8, GRIK5, OPRD1, SLC1A6, EPHA4, ADAM23, GLRA1, EFNB1, CHRNA6, CDH9, DRD1, HTR1B, EFNB2, FXYD6, KCNA2, PSEN2, PTPRS, EFNB3, GRIK4, KCNJ9, CHRM1, SLC6A9, KCNC1, CHRNB2, CHRNA4, CADM3, SLC6A5, DRD2, KCNA3, P2RX3, KCNA1, SYT7, ADORA2A, SLC6A3, CHRM2, SCN10A |
| integral component of spine apparatus membrane | cellular component | CLSTN1 |
| integral component of synaptic membrane | cellular component | PTPRA, GHSR, SYT6, GABRG3 |
| integral component of synaptic vesicle membrane | cellular component | STX12, SYPL1, SYNGR1, GABRA2, STX10, ATP6V1G2, SYT1, VAMP1, SYP, VAMP4, SLC17A6, VAMP3, SV2C, STX16, CLCN3, PTPRN2, VAMP7, OPRD1, ATP8A1, LAMP1, TMEM163, PTPRS, SLC30A3, SLC6A9, SYT9, SV2A, SLC32A1, SLC17A7, SLC6A17 |
| integrator complex | cellular component | INTS7, INTS10, INTS9, ZNF609, INTS2, CT45A8, CT45A9, CT45A2, INTS3, NIPBL, INTS8, INTS14, INTS6, INTS12, SAGE1, INTS11, INTS5, INTS4, INTS1, ESRRB |
| integrin alpha1-beta1 complex | cellular component | ITGB1 |
| integrin alpha10-beta1 complex | cellular component | ITGB1, ITGA10 |
| integrin alpha11-beta1 complex | cellular component | ITGB1, ITGA11 |
| integrin alpha2-beta1 complex | cellular component | ITGB1, ITGA2, LYN |
| integrin alpha3-beta1 complex | cellular component | ITGB1, ITGA3 |
| integrin alpha4-beta1 complex | cellular component | EMILIN1 |
| integrin alpha4-beta7 complex | cellular component | ITGA4, ITGB7 |
| integrin alpha7-beta1 complex | cellular component | ITGB1 |
| integrin alpha8-beta1 complex | cellular component | ITGB1, ITGA8 |
| integrin alpha9-beta1 complex | cellular component | ITGB1, ITGA9 |
| integrin alphaIIb-beta3 complex | cellular component | TSPAN32 |
| integrin alphaL-beta2 complex | cellular component | ITGB2, ITGAL |
| integrin alphaM-beta2 complex | cellular component | ITGAM, ITGB2 |
| integrin alphav-beta3 complex | cellular component | ITGAV, ITGB3 |
| integrin alphav-beta5 complex | cellular component | ITGAV, ITGB5 |
| integrin alphav-beta6 complex | cellular component | ITGB6 |
| integrin alphav-beta8 complex | cellular component | ITGAV, ITGB8 |
| integrin alphaX-beta2 complex | cellular component | ITGAX, ITGB2 |
| integrin complex | cellular component | ITGB1, ITGA5, ITGAV, ITGA4, ITGA6, ITGAE, ITGA2B, ITGB5, ITGA10, ITGAM, ITGA2, ITGB6, ITGB3, ITGB4, ITGB8, ITGAX, ITGB7, ITGB2, ITGA9, ITGA7, ITGAD, ITGAL, ITGA3, ITGA11, ITGA8 |
| intercalated disc | cellular component | ITGB1, CTNNB1, GJA1, ANXA6, ANXA5, ATP2A2, DES, ANK3, YWHAH, CTNNA1, FXYD1, RANGRF, SLC9A1, MYH1, CAV3, SCN1B, DSP, PGM5, ATP1A2, ANK2, DLG1, SCN2A, SLC8A1, CXADR, OBSL1, ANKRD23, SCN1A, PKP2, ATP1B1, GJA5, KCNJ2, HAMP, DSG2, DSC2, ATP1A1, JUP, VAMP5, TMEM65, SCN4B, FHOD1, SCN5A, SPTBN4, GJC1, AKAP6 |
| intercellular bridge | cellular component | XPA, CDC7, SIN3A, SEPTIN2, FAN1, KIF20A, RMDN3, DUSP11, DNAJC8, CEP55, MSRA, SNRNP25, PRKACB, KLHL22, SETX, FAM83D, CD34, NCAPH2, FASTKD2, CEP131, QSOX1, PRC1, RAB35, UNC119, NUDCD2, TPX2, KRR1, MICAL3, KIF2B, AGBL5, C12orf66, SRA1, KIF20B, OLFM4, NTNG2, PKNOX2, PRKACG, ESRRA, GSTM4, USB1, EHD2, CDCA8, KCTD1, RFXANK, KIF23, APC2, FOXL2, MICAL1, NGRN, NINL, RAB11FIP3, EPB41, IQCB1, EAF1, GSTM5, PPP1R13L, PCIF1 |
| intercellular canaliculus | cellular component | STARD10, DPP4, ABCB4, ABCB11 |
| interchromatin granule | cellular component | SMC5, SRSF2, CPSF6 |
| interfibrillar mitochondrion | cellular component | PPARGC1A |
| interleukin-12 complex | cellular component | IL12A |
| interleukin-12 receptor complex | cellular component | IL12RB1 |
| interleukin-13 receptor complex | cellular component | IL13RA1 |
| interleukin-18 receptor complex | cellular component | IL18RAP |
| interleukin-2 receptor complex | cellular component | IL2RB |
| interleukin-23 complex | cellular component | IL23A |
| interleukin-23 receptor complex | cellular component | IL12RB1, IL23R |
| interleukin-28 receptor complex | cellular component | IFNL1, IL10RB |
| interleukin-5 receptor complex | cellular component | SDCBP |
| interleukin-6 receptor complex | cellular component | IL6, IL6R, IL6ST |
| intermediate filament | cellular component | KRT1, VIM, KRT10, GJA1, SYNM, MNS1, KRT38, KRT75, DES, KRTAP10-10, KRT24, NEFH, PLEC, TLK2, KRT73, KRT23, KRT84, MACF1, KRTAP4-5, KRTAP23-1, KRT6B, SLC1A4, KRTAP12-1, KRTAP6-2, KRTAP9-2, KRT6A, KRTAP19-7, MYO5A, KRT18, LMNB1, KRT20, KRTAP19-6, KRT71, KRTAP2-3, KRTAP5-9, DST, KRTAP21-1, KRTAP3-1, KRTAP2-4, KRTAP5-8, FLG, KRT32, DSP, PRPH, KRT222, KRTAP17-1, PNN, CLIP1, KRT19, KRTAP19-3, EPPK1, PPL, NME2, KRT6C, KRT17, KRTAP9-4, EIF6, KRT81, PKP2, NEFM, LMNB2, EVPL, KRT83, KRT86, KRT8, JUP, KRT85, SYNC, KRT82, NME1, KRT9, KRTAP6-1, KRT78, KRT15, KRTAP19-2, IFFO2, KRT74, KRTAP13-1, MICAL1, KRTAP4-8, NCKIPSD, KRT14, KRT7, KRT13, KRT2, KRTAP10-1, KRTAP10-3, KRTAP10-6, KRTAP10-9, KRTAP10-11, KRT72, KRT80, KRT77, EVPLL, GFAP, ADORA2A, KRTAP5-3, KRTAP5-5, IFFO1, BFSP2, LMNTD1, NES, INA, KRTAP20-1, NEFL, KRTAP8-1 |
| intermediate filament cytoskeleton | cellular component | MTRR, VIM, CLK3, SYCE1L, PJA2, DES, SMARCA2, PFDN5, PLEC, SESTD1, CTNS, PSMD10, KRT84, DISC1, NOL9, DST, SMG7, HOXA13, PKN2, CCT8, NSFL1C, PHLDB2, MDN1, MMP14, ZNF175, SLC1A6, EXOSC4, S100A8, KRT17, BCAS3, NDOR1, NEFM, DDX60, EVPL, STN1, SAP30BP, KRT8, SYNE2, ADCY5, KRT13, CARMIL2, KRT80, GFAP, PADI6, ING4, NES, ZNF131, INA |
| intermediate-density lipoprotein particle | cellular component | APOE, APOB, APOA1, APOC3 |
| internode region of axon | cellular component | PARD3, MBP, TUBB4A |
| interphase microtubule organizing center | cellular component | BIRC5, MZT1, WDR60, TCTEX1D2 |
| interphotoreceptor matrix | cellular component | IMPG2, EYS, RBP3 |
| interstitial matrix | cellular component | IGF1, NAV2, ABI3BP, ECM2, TNC, KAZALD1, EGFLAM, SMOC2, MBL2, VWC2, VIT, VWA1 |
| intracellular | cellular component | EGFR, TNF, IFNG, CXCL8, BCL2, IL1RN, BAX, BAK1, HSP90AA1, CDC25A, CDC25C, AXL, ADCY2, GAS6, MTR, PRL, HSPB1, GSTP1, CLU, PRLR, AKR1C3, IFNAR2, GNAI1, GSTK1, ZFP37, GH1, IL2RA, IL5, ITGAV, NOS2, PIK3CA, GFRA1, GPRC6A, KISS1R, IL21, MEFV, FGF17, EZR, APEX1, OXTR, FGF8, SOS1, TWF1, TUBB3, SHH, ZNF331, RNF114, PEX10, FGF3, ACPP, MOV10L1, PRDM9, SIRPG, RABL2A, SERPINA3, MAS1, ANXA5, GDNF, EXOSC10, NXF2, ZNF230, TADA3, C6orf62, RAB18, UBL3, CETN2, NAA20, MOB3A, ZMYND12, ARHGEF3, DDX43, TRNT1, CNOT8, CDC23, ANAPC15, BBS5, CTSB, ATG10, SAT1, RUVBL2, MKKS, ARVCF, CAPN3, ASCC3, CLIC4, EDF1, STMN1, CCND1, NUDCD2, WSB1, OSTF1, RAB14, INTS2, RSPH6A, IKBKG, PLPBP, EEF1AKMT3, GABARAPL1, POLI, GABARAPL2, MAP1LC3B, HSPB8, DEPTOR, ROGDI, RAB5B, SENP7, MAF1, PARP8, MPP1, TIGAR, NAA10, NCALD, LGALSL, RAB17, GDA, FRK, MICU1, FAM126B, NCOA7, RAP1B, CYRIA |
| intracellular canaliculus | cellular component | ABCB11 |
| intracellular cyclic nucleotide activated cation channel complex | cellular component | CNGB1 |
| intracellular ferritin complex | cellular component | FTL, FTH1 |
| intracellular membrane-bounded organelle | cellular component | CYP1A1, PTGS1, SRD5A2, PTGS2, HSD17B4, APOB, CYP17A1, CYP1A2, HMOX1, CYP2B6, FGFR2, PON1, HSD17B3, DNMT3B, PLAGL1, CHD2, GAPDH, APP, MGST1, CLU, SRD5A1, MTOR, BAG6, PON2, GSTK1, CAT, INSR, IGF1R, SLC7A5, APOA1BP, KISS1R, MUC5B, CYP21A2, G6PD, PPARG, CDK9, CYP1B1, CLEC7A, CYP26B1, DNM1L, CLOCK, CYB5A, RANGAP1, GLB1, AGFG1, SHOX, XRCC2, B4GALT2, PRNP, SEC11A, NBR1, E2F5, RAB11FIP2, MARCHF3, SLF2, LPAR4, RBBP8, YIPF4, PNPLA8, TBK1, POMP, HPSE, KIN, LIPF, UGT2B7, ATP6V1B2, SCP2, PPIB, CD38, SMARCA2, CYP2J2, SNX16, RAB11A, SLC35B1, SCAP, ZNF638, RABEP1, PARM1, SPPL2A, ITCH, CGRRF1, MTA3, OSBPL1A, SEC11C, MAP1LC3A, CNNM2, SPHK2, B3GAT1, VPS29, HACL1, AP3M1, CYB5B, HNRNPR, DYRK3, DIAPH2, PDHA1, UGT2B10, CTSK, PPT1, AP2S1, OLR1, CYP4A11, CYP4F3, CCDC93, ARAP1, ALS2, FAAP24, RAB11FIP5, SPG21, CALCOCO1, ATP23, MGST3, SIAH2, HOXA2, RAD51C, SEC31A, CPSF4, PEX11B, OAS1, TFPI, COPB1, SPCS3, SREBF2, NCOA6, PDXDC1, CNST, RHOU, SYT13, GPBP1, CHPT1, MGST2, HDHD3, EPN3, UGT1A8, TMEM165, VTA1, SPINK5, MTPAP, THAP1, AMACR, PIKFYV |
| intracellular organelle | cellular component | SYT1, HOMER2, SYN1, VAMP3, BCL2L14, SLC23A1, SLC5A1, SLC32A1, SLC17A7, ATP6V0A1 |
| intracellular ribonucleoprotein complex | cellular component | BRCA1, FMR1, TERT, GSK3B, SNRPN, GAPDH, PABPC1, ACTB, HNRNPL, RBMX, TEP1 |
| intracellular vesicle | cellular component | RAB29, AP3B2, VAMP3, SLC9B2, SLC5A1, LRIG2, APPL1, ITSN1, TYRP1 |
| intraciliary transport particle | cellular component | KIF3B, DYNC2LI1 |
| intraciliary transport particle A | cellular component | TTC21A, WDR19, WDR35, TTC21B, IFT43, IFT122 |
| intraciliary transport particle B | cellular component | IFT88, IFT22, IFT57, KIF17, IFT74, TTC30A, TRAF3IP1, IFT52, TTC26, UBXN10, IFT46, IFT80, TRIM59, CLUAP1, IFT172, IFT81 |
| intrinsic component of endoplasmic reticulum membrane | cellular component | PGAP3, ESYT2, GRAMD2A, GRAMD1A, ESYT1, CYP2E1, ESYT3, DNAJB2 |
| intrinsic component of endosome membrane | cellular component | ECE1 |
| intrinsic component of external side of plasma membrane | cellular component | F10, F3, ADAM9, FLT3LG |
| intrinsic component of Golgi membrane | cellular component | GOLGA7, CHST4, CHST5, CHST2 |
| intrinsic component of membrane | cellular component | GNAS, RGS16, BNIP3L, TGM1, PICALM, BORCS5, P2RY12, PI4K2A, KCNJ2, MCUB, FAM210B, KCNJ12, APOL1 |
| intrinsic component of mitochondrial inner membrane | cellular component | PPOX |
| intrinsic component of mitochondrial outer membrane | cellular component | MFN1, MFN2 |
| intrinsic component of peroxisomal membrane | cellular component | PEX11G |
| intrinsic component of plasma membrane | cellular component | TLR4, TLR2, ADIPOR1, LY96, TRO, KCND2, S1PR1, ADIPOR2, CD63, SLC8A3, CD48, SCN2A, ADCY6, RAB26, OPRD1, ALCAM, TGM2, CRHR1, TREM2, PDGFRB, TNFRSF21, XPR1, PDGFRA, PTPRZ1, CD6, GPC1, GPC3, SCN4B, HCN4, SLC34A1, UNC5A, EFNA3, SLC10A7, TRPV1 |
| intrinsic component of the cytoplasmic side of the plasma membrane | cellular component | MIEN1, SPTB, PALM, RASA3 |
| invadopodium | cellular component | SVIL, RUFY3, MSN, ACTR2, PDPN, FSCN1 |
| invadopodium membrane | cellular component | ITGB1, PLAUR, NOX1, DPP4, ITGA3 |
| inward rectifying potassium channel | cellular component | ABCC9, ABCC8 |
| ion channel complex | cellular component | PHLPP2, LRRC28, LRRC8D, LRRC8C, LRRC8B, PHLPP1 |
| IPAF inflammasome complex | cellular component | CASP1, CASP4, NAIP |
| Ire1 complex | cellular component | ERN1 |
| IRE1-RACK1-PP2A complex | cellular component | RACK1, ERN1 |
| IRE1-TRAF2-ASK1 complex | cellular component | ERN1, MAP3K5, ERN2, TRAF2 |
| isoamylase complex | cellular component | AGL |
| ISWI-type complex | cellular component | SMARCA5 |
| junctional membrane complex | cellular component | TRDN, JPH4, CASQ2, RYR1, JPH3, JPH2, JPH1 |
| junctional sarcoplasmic reticulum membrane | cellular component | TRDN, JPH4, CASQ2, RYR1, RYR2, JPH3, JPH2, ASPH, JPH1, AKAP6 |
| juxtaparanode region of axon | cellular component | KCNAB1, EPB41L3, CNTN2, SIRT2, CNTNAP2, DLG4, KCNA2, KCNAB2, KCNA1, DLG2 |
| kainate selective glutamate receptor complex | cellular component | GRIK3, GRIK5, GRIK4, GRIK1, GRIK2 |
| katanin complex | cellular component | KATNB1 |
| keratin filament | cellular component | KRT1, KRT75, CSNK1A1, KRTAP10-10, KRT73, KRT84, KRTAP4-5, KRT6B, KRTAP12-1, KRTAP9-2, KRT6A, KRT18, KRT71, KRTAP2-3, KRTAP5-9, KRTAP3-1, KRTAP2-4, KRTAP5-8, EPPK1, KRT6C, TCHP, KRTAP9-4, KRT81, FAM83H, KRT83, KRT86, KRT8, KRT85, KRT82, KRT78, KRT74, KRTAP4-8, KRT14, KRT7, KRT13, KRT2, KRTAP10-1, KRTAP10-3, KRTAP10-6, KRTAP10-9, KRTAP10-11, KRT72, KRT80, KRT77, KRTAP5-3, KRTAP5-5, FBF1, GPER1 |
| keratohyalin granule | cellular component | CELA2A, FLG, HRNR |
| KICSTOR complex | cellular component | C12orf66, BMT2, SZT2, ITFG2, KPTN |
| kinesin complex | cellular component | KIF26B, KIF6, KLC4, STARD9, KIF5B, CENPE, KIF17, KIF2A, KIF20A, KIF1C, KIF19, KIF24, KLC2, KIF15, KIFAP3, KLC1, KIF14, KIF12, DISC1, KIFC1, KIF1B, KIF16B, KIF5A, KIF2B, YWHAE, KIF20B, KIF18A, KIFC3, KIF27, KIF9, KIF4A, KIF3C, KIF1A, KIF23, KLC3, KIF13B, NDE1, KIF21B, KIF7, KIF18B, KIF25, KIF26A, KIF4B, KIF11, KIF22, KIF13A |
| kinesin I complex | cellular component | KLC2 |
| kinesin II complex | cellular component | KIF3B, KIF3A, KIFAP3 |
| kinetochore | cellular component | BIRC5, 39326, RANGAP1, SIN3A, DYNLL1, HNRNPU, CENPE, SEPTIN2, CSNK1A1, SUMO3, NUP37, NUP85, MIS12, PPP1R12A, ZW10, BUB3, NUP107, NUP43, TRAPPC12, DSN1, NDC80, SPDL1, CENPN, XPO1, SEC13, ANAPC16, DYNC1I1, BUB1, BUB1B, DYNLT3, PHF6, SPC24, CENPI, CENPT, SUGT1, ZNF207, PHF2, DCTN3, ITGB3BP, DCTN6, ZWINT, DCTN5, ZWILCH, DYNC1LI2, SGO1, NUDCD2, CENPF, SEH1L, PSEN1, PLK1, MAD2L1, BOD1L2, KIF2B, APC, RASSF2, NUP133, BOD1, CLIP1, CENPU, KANSL1, GPATCH11, AHCTF1, MAD1L1, DYNC1LI1, CENPX, TTK, KIF18A, SKA2, MEAF6, FBXO28, CFDP1, SS18L1, DCTN2, SMC1A, NSL1, KNSTRN, TPR, NUP98, TP53BP1, CKAP5, SGO2, CENPW, TBCB, DCTN4, CENPC, CLASP2, SPOUT1, PMF1, PSEN2, SKA1, CBX5, MTBP, CENPM, NDE1, CENPA, CENPS, KAT2B, SPC25, CLASP1, AURKB, CENPQ, PINX1, INCENP, KNTC1, NEK2, NUP160, KIF22, CENPK, CENPO, NUF2, CENPH, SEPTIN7, CENPV |
| kinetochore microtubule | cellular component | CENPE, RAB11A, ZW10, KIF18A, CLASP2, CLASP1, KNTC1 |
| kinociliary basal body | cellular component | MKKS |
| kinocilium | cellular component | STRC, ELMOD3, DCDC2 |
| Ku70:Ku80 complex | cellular component | XRCC5, XRCC6, PAXX |
| L-cysteine desulfurase complex | cellular component | FXN, LYRM4 |
| L-type voltage-gated calcium channel complex | cellular component | CACNA2D1, NOS1AP, CACNG6, CACNA1C, CACNG7, CACNG4, CACNA1D, CACNG1, CACNB3, CACNB2, CACNG8 |
| lamellar body | cellular component | SMPD1, SFTPB, CKAP4, SFTPC, KRTDAP |
| lamellar body membrane | cellular component | ABCA3 |
| lamellipodium | cellular component | CIB1, ITGB1, CTNNB1, PIK3CA, MEFV, CDH1, NF2, AIF1, WASL, SHTN1, PSTPIP1, CORO1B, NRBP1, DDX3X, MYH10, ACTR3, MTSS2, PALLD, ARPC3, IQGAP2, FAT1, ALS2, RAB3IP, ABITRAM, WASF3, NCKAP1, SNX2, PXN, ARHGEF7, PPP1R9B, CTTNBP2NL, CTNNA3, P4HB, CTNNA1, VASP, DPYSL3, CORO1C, ARPC5, PTK2, STX3, HAX1, CTNND1, ARHGEF6, TSC1, ABI2, CTNNA2, CTTN, CCDC88A, AJUBA, GDPD2, SWAP70, ABLIM1, SLC9A1, BCAR1, CAPRIN1, AMOT, SH3RF1, PLEKHH2, APBB2, ACTC1, PKD2, PIP5K1A, ROCK1, SCRIB, ARAP3, DBNL, ANGPTL3, DGKZ, PKN2, PLCE1, SRGAP2, PTPN13, NEDD9, RAPH1, FSCN3, ITGB1BP1, FLOT1, SORBS2, UNC5C, APC, ARHGAP31, FGD6, RUFY3, KLHL2, PTPRM, RAC1, SPATA13, EVL, WASF2, RAC2, FER, DPP4, VAMP7, CYFIP1, ABI1, RDX, CARMIL1, FAM89B, ENAH, PARVB, NME2, ACTR2, NHS, WASF1, TESC, MYO10, PARVA, HCLS1, CAPG, FGD4, PPP1R9A, PODXL, ILK, PTPRO, PDPN, SCYL3, CDC42BPB, EPHA2, RAC3, TWF2, FGD2, SSH1, AVIL, RAPGEF3, KCNA2, MCC, PDLIM4, CDK5, STX4, DAG1, CORO1A, PHACTR4, DYSF, KPTN, APBB1, PLEKHG5, LIMK1, MYLK, CARMIL2, PDXP, SH3BP1, PLXND1, MYO1G, ITSN1, FSCN1, |
| lamellipodium membrane | cellular component | ITGAV, ANTXR1, FERMT2, NCKAP1, VASP, CSPG4, PLEK2, ITGB3, SLC39A6, DOCK8, DPP4, PDPN, EPHA2, KCNA2, SYNE2, APC2, PDXP, PLXND1, PIEZO1 |
| lamin filament | cellular component | NARF, LMNB1, EIF6, LMNB2 |
| laminin complex | cellular component | NTN4, MEGF9, LAMB1, LAMB3 |
| laminin-1 complex | cellular component | LAMC1, LAMB1 |
| laminin-10 complex | cellular component | LAMC1, LAMB1, LAMA5 |
| laminin-11 complex | cellular component | LAMC1, LAMA5 |
| laminin-2 complex | cellular component | LAMC2, LAMB1 |
| laminin-5 complex | cellular component | LAMB3, LAMA3, LAMA5 |
| laminin-8 complex | cellular component | LAMB1 |
| large ribosomal subunit | cellular component | MRPL17, MRPL22, MRPL15, RPL13A, RBM3, MRPL10, RPL8, MRPL11, RPL27A, RPL12, RPL10A, RPL26L1, RPL17, RPL26, MRPL1 |
| late endosome | cellular component | MAPK3, MAPK1, TF, IGF2R, SRC, GJA1, F2R, RAP1A, NTRK1, HSPA8, VPS41, RAB9A, NBR1, SLC38A9, DERL2, AP5M1, LAMTOR3, ASTN2, DDIT3, SNX16, CXCR4, MTM1, PARM1, SPPL2A, TSG101, OSBPL1A, MAP1LC3A, VPS29, CD74, VPS18, RAB27A, BST2, AP1AR, DERL1, STX8, RAPGEF2, SLC31A2, ANKRD27, AP5S1, SNX14, CTNS, VPS36, VPS26B, ANKRD13A, LGMN, SLC30A2, TMEM59, VPS33B, LDLR, M6PR, VIPAS39, ATP13A2, PSAP, ARF1, PIK3C3, RAB22A, MYO5A, RAB27B, DYNC1LI2, LAMP2, ATP7B, CD63, ABCA5, STX7, IFNAR1, RAB14, SQSTM1, SLA2, RAB7A, ELAPOR1, KIDINS220, SMIM22, MAP2K2, TTPA, CLCN3, ATG9A, TICAM2, NSG2, CLTCL1, ATP7A, EXOC8, WDR48, RUBCN, PIK3R4, UVRAG, GRIN2B, LAMP1, CTSS, SLC11A1, CLN3, APOA5, GRN, HTT, MAP2K1, ANKRD13B, DENND10, RILP, CHID1, SLC31A1, STARD3, UNC13D, TMEM25, RNF128, SLC9A6, GNPNAT1, VPS16, CD1E, SLC30A3, CST7, BACE1, TCIRG1, RNF133, DYSF, VAMP5, NSG1, MFSD12, VPS33A, CLEC16A, ANKRD13D, PCSK9, NMNAT2, MCOLN1, MICALL1, SIGLEC1, MVB12B, TMEM9, CHMP3, RNF215, MAGI2, VPS39, VPS35, FYCO1, SLC30A4, RNF148, RAB9B |
| late endosome membrane | cellular component | HLA-DRB1, HLA-DRA, NTRK1, ANXA2, GALNTL5, ANXA6, VPS41, SLC38A9, AP5M1, LAMTOR3, CHMP2A, SNX16, SPPL2A, TSG101, ARL8B, VPS18, VPS28, LAPTM4B, TMEM165, STX8, PIKFYVE, VPS4B, PLD1, CHMP4A, AP5S1, VTI1B, LAMP3, SNX14, SCARB2, VPS36, VAMP8, TMEM59, VPS33B, CHMP4B, ATP13A2, STARD3NL, WDR91, LAMP2, HLA-DMB, CHMP6, OSBPL11, STOML1, CD63, MMD, SLC9A9, CYB561A3, ABCA5, WDR81, MITD1, RAB7A, LAPTM4A, ELAPOR1, UBXN6, IFITM3, OSBPL9, VPS37C, CLCN3, RNF13, VAMP7, ATG9A, TICAM2, ARL8A, LITAF, NSG2, GOSR2, MR1, SNF8, ADAM30, NPC1, TSPAN15, VAC14, VPS37A, MCOLN3, CDIP1, VPS37B, TMEM106B, LAMP1, SLC11A1, CLN3, LAMTOR1, RMC1, YIPF2, CHMP4C, MVB12A, RILP, STARD3, MARCHF1, VTI1A, ABHD6, VPS16, CLCN4, MARCHF8, SLC30A3, YIPF1, PIP4P1, NSG1, VPS33A, PLD3, MCOLN1, BAIAP3, MICALL1, MVB12B, SLC39A14, MCOLN2, SLC29A3, TMEM9, CHMP3, VPS39, SLC30A4, ANXA8, CHMP1B, PIP4P2 |
| lateral cell cortex | cellular component | GPSM2, NUMA1 |
| lateral element | cellular component | REC8, SYCP3, KASH5, SMC3, SYCP2L, BLM, SYCP2, INCENP |
| lateral loop | cellular component | SIRT2, DLG1, STX4 |
| lateral plasma membrane | cellular component | CTNNB1, CDH1, GJA1, PKD1, ATP6V1B1, GPSM2, IQGAP1, SLC12A2, ANK3, DMD, EPCAM, MARK2, CLDN15, CLDN12, BVES, CORO1C, DVL1, ARL2, IQGAP3, ANXA1, GJB1, FZD3, SLC26A5, AXIN1, DSG1, APC, GNA12, DLG1, KCNB1, VANGL2, DVL2, TACSTD2, NUMA1, ATP1B1, ERBB3, DSG2, PTPRO, TBCD, C1QTNF5, CEACAM1, ATP1A1, ATP1B2, JUP, SLC16A1, MYO1C, CLDN1, MTCL1, CLDN7, NSG1, SNTA1, VANGL1, NKD2, CLDN4, ABCC6, DRD2, PPP2R1A, SCN5A |
| leading edge membrane | cellular component | CDC42, AMPH, DOCK8, EPHA2, ADGRE2, MYO1G, ARHGAP44 |
| leading edge of lamellipodium | cellular component | DUSP22, PDPN |
| Lewy body | cellular component | GPX1, ARIH1, PRKN, SQSTM1, PINK1 |
| Lewy body core | cellular component | HERPUD1, ATF4, FBXO7 |
| Lewy body corona | cellular component | FBXO7 |
| Lewy neurite | cellular component | FBXO7 |
| lipid particle | cellular component | GAPDH, LIPE, ANXA2, CIDEA, RAB18, G0S2, SCCPDH, METTL7A, ZW10, PLIN2, PRPF19, DHRS3, TMEM135, ABHD5, FAF2, PLA2G4C, CES1, LSS, IRAK1, NSDHL, ACSL3, TSC1, DGAT2, FAAH2, RSAD2, ZFYVE1, RBP1, OSBPL2, CKAP4, HSD3B7, STARD13, RAB7A, ATG2B, SPART, PNPLA3, BCAP31, PNPLA4, TRAF6, ACSL4, PLA2G4A, ADIG, PITPNM1, CYB5R3, HSD17B11, SYNGR2, GIMAP2, HILPDA, RDH10, EDA, AUP1, PLIN3, RAB5C, GBF1, LMLN, SIGMAR1, CTDNEP1, SET, RAB3GAP1, LPCAT2, LPCAT1, AQP10, ATG2A, PNPLA7, ABHD4, PNPLA1, RAP1B, PNPLA5, GIMAP7, LDAH, SPAST, CAV1, C18orf32 |
| lipid tube | cellular component | BIN1 |
| lipopolysaccharide receptor complex | cellular component | TLR4, HSPD1, LY96 |
| longitudinal sarcoplasmic reticulum | cellular component | ATP2A2 |
| low-density lipoprotein particle | cellular component | APOE, APOB, SELENOS, LSR, LDLR, APOF, APOO, APOA1, PLA2G7, APOA5, APOM, APOBR |
| Lsm1-7-Pat1 complex | cellular component | LSM1, LSM3, LSM7, LSM2 |
| Lsm2-8 complex | cellular component | LSM3, LSM6, LSM8, LSM7, LSM2, LSM4 |
| lumenal side of Golgi membrane | cellular component | NUCB1 |
| lumenal side of lysosomal membrane | cellular component | HSPA8, CTSA |
| lumenal side of membrane | cellular component | AQP2 |
| lysosomal lumen | cellular component | DCN, HSP90AA1, FASLG, HEXA, CTSD, HEXB, ASAH1, ARSA, RNASET2, MAN2B1, GC, GBA, GAA, GLB1, FUCA1, HSPA8, GPC2, HPSE, CD74, GLA, CTSK, GYG1, PPT1, ACP2, CTSV, CTSL, IFI30, IDS, GPC5, SCARB2, GUSB, SDC2, CSPG4, LGMN, SMPD1, LIPA, BCAN, ATP13A2, PSAP, SDC4, PLBD2, EPDR1, GPC6, LAMP2, SGSH, GALC, OMD, MANBA, ACAN, PRELP, CTSA, ARSB, BGN, CTSF, TPP1, GNS, GALNS, NSG2, HSPG2, TCN2, CTSS, NAAA, TXNDC5, NEU1, CHID1, GPC4, PDGFRB, IDUA, CD1E, GPC1, CSPG5, NSG1, GPC3, NAGLU, NEU4, AGRN, PLD3, MAN2B2, NCAN, CUBN, SDC3, SDC1, CBLIF, KERA, OGN, GM2A |
| lysosomal matrix | cellular component | LAMP2 |
| lysosomal membrane | cellular component | EGF, HLA-DRB1, HLA-DPB1, HLA-DQB1, CFTR, WDR11, ATP6V0A2, HLA-DRA, MTOR, GNAI1, HLA-DQA1, IGF2R, CD68, ANXA2, ACPP, GBA, ANXA6, GAA, GOPC, HSPA8, VPS41, BLOC1S2, SLC38A9, AP5M1, TMEM9B, LAMTOR3, HPSE, ATP6V1D, GPR137B, ATP6V1G1, ATP6V1B2, ZNRF2, SPPL2A, TMEM74, SPHK2, ARL8B, AP3M1, ATP6AP2, CD74, SLC15A4, RNF183, TM6SF1, VPS18, ACP2, ABCC10, LAPTM4B, DTX3L, TMEM165, STX8, AP3B1, LAMTOR5, ECE1, NSF, SEC13, RAB2A, CCZ1B, CCZ1, PLD1, NPRL2, KXD1, TMEM79, AP5S1, VTI1B, LAMP3, SNX14, AP1G1, CTNS, SNAPIN, AP1S2, SCARB2, SLC36A1, VAMP8, EVA1A, MIOS, AP3D1, GNAI3, ATP6V1E1, CLCN7, AP1S1, GNB1, DAB2, ATRAID, RRAGA, SLC30A2, TMEM59, VPS33B, GNB4, ITM2C, M6PR, SLC48A1, SCARB1, ATP13A2, SLC17A5, DEPDC5, TMEM63A, STARD3NL, PSAP, ATP6V1A, VLDLR, RRAGB, SLC66A1, BORCS5, ANKFY1, HLA-DQA2, LAMP2, HLA-DMB, STX17, BLOC1S1, HGSNAT, MFSD8, GLMP, SPG11, RDH14, HPS4, CD63, ENPP1, CYB561, MMD, CYB561A3, SPPL2B, ABCA5, AP2M1, SEH1L, SLC49A4, WDR41, SLC12A4, STX7, HLA-DOA, PSEN1, RAB14, AHNAK, WDR81, MEAK7, OSTM1, GPR137, SLC39A8, MYO |
| lysosome | cellular component | SOD1, IL1B, HLA-DRB1, HLA-DPB1, ACE, HLA-DQB1, FASLG, HLA-DRA, HEXA, CTSD, HEXB, MTOR, PON2, HLA-DQA1, CAT, IGF2R, SRC, CD68, ASAH1, ARSA, GJA1, SPACA3, ACPP, NPC2, RNASET2, MAN2B1, GBA, GAA, GLB1, FUCA1, HSPA8, VPS41, LRBA, RAB9A, NBR1, BLOC1S2, MARCHF3, SLC38A9, AP5M1, TMEM9B, HPSE, GPR137B, VPS26A, SNX16, CXCR4, MLC1, ZNRF2, SPPL2A, RB1CC1, TMEM74, SPHK2, ARL8B, AP3M1, ATP6AP2, CD74, GLA, CTSK, PPT1, CTSW, RAB38, ANK3, VMA21, RNF183, FNBP1, TM6SF1, USE1, VPS18, PCYOX1, SNX2, BCL10, ACP2, CAPN2, RAB27A, LAPTM4B, DTX3L, C9orf72, TMEM165, CPQ, LAMTOR5, CTSV, CTSL, CTSB, IFI30, IDS, CD1C, SNCA, SEC13, CCZ1B, CCZ1, CALCRL, NPRL2, ANKRD27, KXD1, TMEM79, AP5S1, VTI1B, LAMP3, SNX14, CTNS, SNAPIN, CTSC, OCRL, SCARB2, KLHL22, SLC36A1, VPS36, VAMP8, EVA1A, MIOS, ASS1, GUSB, CD34, CLCN7, RRAGA, SHKBP1, DNASE2B, LGMN, SLC30A2, TMEM59, VPS33B, SIAE, ITM2C, HGS, RAMP2, LDLR, SMPD1, M6PR, LIPA, SLC48A1, ATP13A2, SLC17A5, DEPDC5, TMEM63A, PSAP, RNASE2, PRDX6, PRCP, RRAGB, SLC66A1, PLBD2, GGH, BORCS5, EPDR1, MYO5A, DYNC1LI2 |
| lytic vacuole | cellular component | UVRAG |
| M band | cellular component | ENO1, ANK1, NBR1, PPP2R5A, LRRC39, MYOM2, CRYAB, SPTBN1, MYOM3, KLHL41, TTN, ALDOA, FHL2, ANK2, OBSCN, OBSL1, LMOD2, MYOM1, CMYA5, SMTNL1, S100A1 |
| m-AAA complex | cellular component | AFG3L2, SPG7 |
| macromolecular complex | cellular component | MTOR, SKIL, ATP2A2, RPL3, PEX19, RPL5, NASP, HDAC4, RPS7, HNRNPU, PPFIA1, IKZF1, PCM1, HSPH1, CCDC113, SPATS2L, CAB39, KIN, ERLIN1, UBR5, NPM1, SCP2, PPIB, CANX, CXCR4, RAB11A, GPSM2, SCAP, STK3, KEAP1, PTGES3, RABEP1, SRCAP, ZC3H18, CIR1, ZNRF2, ITCH, QTRT2, HIGD1A, OGT, CCP110, ACTL6A, CD74, XRCC5, PRKAR2A, FEN1, IQGAP1, RPL11, TJP1, LTBP1, MAPK6, ZC3H12A, MIER3, CARM1, RNF168, MIER1, ALS2, MFF, PRELID1, GOLT1B, SCIN, SNX2, BCL10, PEX11B, HNRNPC, DMD, PIK3R1, CPS1, ST13, SMARCA4, RBM10, TFCP2, STK4, DDX39B, ARHGEF7, KIF24, METTL21C, CNST, ILDR1, DTX3L, HDAC2, FBXW7, NUP58, KLC2, ALK, SH3GLB1, PRKAB1, RAPGEF2, MAGED1, XPO1, LAMTOR5, ZMPSTE24, CRYAB, P4HB, HSP90B1, BCL3, PTN, GTF2F1, SNCA, IRAK1, SEC13, UBE2N, CFHR1, STT3B, COX11, SNX4, NUP62, UTRN, GRB10, NAE1, HES1, RBBP6, SLC41A1, IPO4, METTL21A, DDB2, SMARCE1, USP28, RBM4B, STAP1, SUGT1, NCOA3, CPLX1, PRKN, LY6G6C, ANXA1, BCR, ZNF10, RYR1, WARS1, SYK, HCFC1, DCAF7, TRA2B, TSC1, RYR2, CDK5RAP3, ARHGAP33, ATG12, METTL18, GJB1, CAPN3, PTPN6, HIRA, SPTBN1, DP |
| macrophage migration inhibitory factor receptor complex | cellular component | CD44, CD74 |
| macropinocytic cup | cellular component | SNX5 |
| macropinosome | cellular component | ANXA2, ANKFY1, CLIP1, MMP14, CARMIL1, APPL2, APPL1, CARMIL2 |
| main axon | cellular component | APP, C9orf72, MAP2, TIAM1, APBB1, TRIM46 |
| male germ cell nucleus | cellular component | TNP1, HSPA2, TNP2, REC8, MLH1, MLH3, H2AFX, KIF6, SYCP1, TCFL5, TRIP13, TOPBP1, MORC1, ACTL7A, ACTRT3 |
| male pronucleus | cellular component | CCNA2, CBX1, TET3, RIF1, STPG4 |
| MAML1-RBP-Jkappa- ICN1 complex | cellular component | NOTCH1, RBPJ, MAML1 |
| manchette | cellular component | CCDC181, RIMBP3B, ACTR1A, LRGUK |
| mannosyltransferase complex | cellular component | PIGV |
| mast cell granule | cellular component | KIT, AKR1B1, SNAP23, ANXA1, RASGRP1, LAT2, PLA2G3, CXCR2, SRGN, MRGPRX2, CBL, LYN, PIK3CG, BTK, PIK3CD, LAT, NR4A3, CPLX2, S100A13 |
| matrix side of mitochondrial inner membrane | cellular component | COA8, DNAJC19, BDH1 |
| mature chylomicron | cellular component | APOB |
| MCM complex | cellular component | MCM3, MCM8, MCM9, MCM5, MMS22L, MCM4, MCM7, MCM6, MCMBP, TONSL, MCM2, MCMDC2 |
| MCM8-MCM9 complex | cellular component | MCM8, MCM9 |
| mediator complex | cellular component | MED7, CCNC, MED4, MED8, BCLAF1, HAVCR2, MED21, MED10, MED14, MED6, MED12L, MED13, MED23, MED31, MED13L, MED25, CDK19, MED26, MED30, MED28, MED16, MED12, MED15, THRAP3, MED18, PPARGC1B, MED9, MED24, MED22, MED27, MED19, BCLAF3 |
| meiotic cohesin complex | cellular component | REC8, STAG3, SMC3, RAD21, SMC1A |
| meiotic nuclear membrane microtubule tethering complex | cellular component | KASH5, CLMN, SYNE4, SYNE2, SUN2, SYNE1 |
| meiotic spindle | cellular component | HSPA2, BORA, ASPM, SIRT2, TUBB8, MAPK15 |
| meiotic spindle midzone | cellular component | INCENP |
| meiotic spindle pole | cellular component | KASH5 |
| melanosome | cellular component | HSP90AA1, ITGB1, CTSD, HSPA5, PDIA3, ANXA2, PRDX1, MYRIP, ANXA6, HSPA8, CCT4, RAB9A, CALU, ATP6V1B2, PPIB, CANX, RAB29, SEC22B, NAP1L1, RAB38, SLC1A5, SYPL1, SYNGR1, RAB27A, RAB1A, P4HB, CTSB, HSP90B1, RAB2A, SLC24A5, ANKRD27, CTNS, STX3, TFRC, PDIA6, RPN1, RAB5A, MYH11, SLC1A4, RAB32, ATP6V1G2, PDIA4, STOM, RAB35, GGH, MYO5A, RAB27B, YWHAZ, HPS4, CD63, TYR, ANXA11, TRPV2, FASN, FLOT1, ITGB3, CNP, YWHAE, RAN, SDCBP, TPP1, AHCY, MMP14, RAC1, SYTL2, TMED10, CLTC, DNAJC5, SGSM2, YWHAB, PDCD6IP, LAMP1, CAPG, RAB5B, ATP1A1, RAB5C, SLC3A2, TMEM33, SYTL1, RAB17, SERPINF1, ATP1B3, MYO7A, SND1, GPR143, TYRP1, DCT, ATP6V0A1 |
| melanosome membrane | cellular component | RAB38, RAB27A, GPNMB, RAB32, DTNBP1, SLC45A2, TYR, RAB7A, OCA2, TH, GPR143, TYRP1, DCT |
| membrane | cellular component | DDX3Y, EGFR, EGF, TNF, HLA-DRB1, APOE, ESR1, HLA-DPB1, CYP1A1, ICAM1, PGR, MMP2, IL6R, BCL2, CYP19A1, ACE, VEGFA, CD44, TNFRSF1A, TNFRSF1B, KITLG, LHCGR, PTGS1, ANOS1, FSHR, FAS, NOS3, SRD5A2, PTGS2, IL6ST, CASP4, TNFSF10, HSD17B4, GNAS, PLOD1, FMR1, BAX, BAK1, AMHR2, MEST, NOSTRIN, CATSPER1, CMTM2, RXFP2, BCL2L2, CATSPER2, CCNB2, HLA-B, HLA-DQB1, HLA-A, ERBB2, CYP17A1, CYP1A2, CDK1, HSP90AA1, ABCB1, HMOX1, MTHFD1, CFTR, HLA-E, CCNB1, MGMT, FLT1, CYP2B6, FGFR2, FGFR3, TYK2, AXL, AKT1, KDR, KIR2DL2, KIR2DS2, FASLG, GSK3B, NR0B1, UBE2B, DLK1, S100A12, ADCY2, KANK1, CIB1, WDR11, ATP6V0A2, TLR4, MGEA5, TLR2, SEMA7A, MTA2, HLA-DRA, KRT1, GAPDH, APP, CYP11A1, ITGB1, ENO1, HEXA, HEXB, ITGA5, GNAO1, PARP1, MGST1, CLU, FGFR1, F5, F3, HSD3B1, CYP11B1, PRLR, SRD5A1, EDNRA, HSD3B2, GNRHR, ABCC1, CTNNB1, HSD17B2, MTOR, VDAC2, BAG6, LEPR, IFNAR2, PGF, HSPA2, B2M, GNAI1, TGFBR3, PLAUR, CLCA4, PON2, HFE, NSMF, IGSF1, BAD, PARK7, G6PC3, IL1RAPL1, MAN1B1, GSTK1, RTL1, IL2RA, HLA-DQA1, CAT, SERPINA5, INSR, ITGAV, YES1, IGF1R, K |
| membrane attack complex | cellular component | C6, C5, C8G, C7 |
| membrane coat | cellular component | SYNJ1, CHMP2A, AP2S1, COPB2, COPB1, COPZ1, AP3B1, CHMP4A, AP1G1, AP1S2, AP3S2, AP3D1, AP1S1, AP3S1, CHMP4B, AP2A2, AP3B2, ARL6, AP1G2, AP1S3, COPG1, AP2B1, COPA, AP1B1, AP4B1, COPG2, DNM1, AP2A1, AP4E1, CHMP1B |
| membrane protein complex | cellular component | SLC1A2, SLC1A3, SLC1A6 |
| membrane raft | cellular component | EGFR, TNF, ICAM1, TNFRSF1A, TNFRSF1B, FAS, KDR, CASP3, FASLG, GSK3B, ADCY2, CASP8, TLR2, APP, ITGB1, CTSD, EDNRA, VDAC2, GNAI1, PARK7, CD79A, EZR, GJA1, SHH, PGK1, ANXA2, NF2, TEX101, VDAC1, ACE2, PRNP, LDHB, GLIPR1L1, STX12, SORBS1, HPSE, JAK2, MLC1, CD55, SLC6A2, IQGAP1, PPT1, RAP2B, PPP2CA, OLR1, BCL10, GNAI2, DMD, TDGF1, CAPN2, BST2, BAALC, RTN4R, PIKFYVE, PPP2R1B, KIRREL1, SLC9A3R1, KRAS, CD226, DLC1, GNAI3, SLC1A2, PLPP1, SYNJ2, RAB5A, GPM6B, GHSR, LAT2, SLC25A5, EEF2, SLC9A1, S1PR1, STOM, SDC4, MALL, LYPD6, STOML2, ITGAM, LAMP2, ZAP70, EMP2, TEK, CNTN1, FADD, RIT2, STOML1, ARID3C, EPHB1, CAV3, ATP1A4, TLR1, GRIP1, LRP6, PTPRC, PSEN1, CAV2, AHNAK, EFHD2, CFLAR, TUBB, CD48, EDNRB, BIRC2, ANGPT1, LTB4R, FLOT1, RHOQ, CNR1, ANK2, DLG1, ARID3A, SDCBP, TPP1, ANXA13, SLC6A4, ADCY8, RFTN1, FYB2, RGMB, MAL2, PLSCR1, CBL, DPP4, CXADR, LYN, VCL, ABCB4, TGFBR1, OPRD1, ATP7A, PRKCZ, MYADM, PI4K2A, NPC1, FAIM2, ERLIN2, CD2, SLC2A4, BTK, HYAL2, CLN3, LAMTOR1, PODXL, IKBKB, ITGB2, EFNB1, TRADD, PDPN, ITLN1, TRPC5, CD4, |
| membrane-bounded organelle | cellular component | GSK3B, KIF5B, NAPEPLD, PSEN1, TMEM258 |
| mesaxon | cellular component | MAG |
| messenger ribonucleoprotein complex | cellular component | LSM1, LSM14A, YBX1, CPEB4, CPEB1, CPEB2, CPEB3, PKP2, PKP3 |
| methionine adenosyltransferase complex | cellular component | MAT2B, MAT2A |
| methylcrotonoyl-CoA carboxylase complex | cellular component | MCCC1, MCCC2 |
| methylosome | cellular component | CLNS1A, WDR77, SNRPE, SNRPB, SNRPD1, SNRPD2, SNRPG, PRMT1, ERH, SNRPF |
| methyltransferase complex | cellular component | RIOK1 |
| MHC class I peptide loading complex | cellular component | TAP1, TAP2, TAPBP, CALR |
| MHC class I protein complex | cellular component | HLA-B, HLA-A, HLA-E, B2M, HFE, HLA-G, AZGP1, HLA-C, MR1, HLA-F |
| MHC class Ib protein complex | cellular component | HLA-E, HLA-F |
| MHC class II protein complex | cellular component | HLA-DRB1, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DQA1, CD74, HLA-DQA2, HLA-DMB, HLA-DOA, HLA-DPA1 |
| MIB complex | cellular component | DNAJC11, SAMM50, MTX2, CHCHD6, APOO, MTX3, IMMT, MICOS10, MTX1, MICOS13, CHCHD3 |
| microfibril | cellular component | LTBP1, FBN2, MFAP1, FBN1, MFAP4, MFAP2, MFAP5, THSD4, ADAMTS10 |
| microprocessor complex | cellular component | DROSHA |
| microspike | cellular component | EZR, PROM2, FSCN1, SDC3 |
| microtubule | cellular component | FKBP4, BIRC5, ODF2, TUBB2B, NCOA2, MEFV, TUBB3, DNAH9, DNM1L, KIF3B, DYNLT1, TUBA4A, TUBA3C, KIF26B, KIF6, DNAH12, DYNC2H1, TEKT4, KATNB1, TEKT3, RASSF1, KLC4, TUBA8, DNAH1, TEKT2, KIF3A, DYNLL1, DYNC1H1, DNAH5, DNAH11, DNAI1, SHTN1, SYNJ1, KIF5B, CCT5, EMD, CCT4, CENPE, ABRAXAS2, CAMSAP1, CEP57, SHROOM3, HSPH1, DNAH6, DYNLRB1, HAUS2, DNAH2, KIF17, DNAH17, TUBGCP4, SEPTIN9, KIF2A, KIF20A, DYRK1A, DPYSL2, EFHC2, RMDN3, CCT7, TPPP3, NUSAP1, FHDC1, MAP1LC3A, TCP11L1, BAIAP2, KIF1C, IQGAP1, CAMSAP2, IQGAP2, NAV1, DYNLRB2, RMDN1, BEX4, TOGARAM1, CCT2, KIF19, CEP170, KIF24, NIN, KLC2, HAUS4, KIF15, BCL2L11, KATNA1, TCP1, CCT6A, CCDC181, LRRC49, TCTE3, DYNC2LI1, RMDN2, MAPRE3, DYNC1I1, DVL1, DYNLT3, TPPP2, KLC1, DYNC1I2, EIF3A, KIF14, TTLL7, TPGS1, CDK5RAP2, MID1IP1, MACF1, ZNF207, DCTN3, HAUS5, MAP4, ASPM, KIF12, CDK5RAP3, CDK2AP2, TTLL1, CCT3, TUBB2A, HOOK3, RASSF3, MAP6D1, DISC1, CCDC66, PRC1, STMN1, RP1, TBCC, KIFC1, RCC2, DNM3, DYNC1LI2, KIF1B, WDR47, SARM1, SIRT2, RASSF5, HOOK2, KIF16B, FEZ1, DCDC2, TUBE1, TPX |
| microtubule associated complex | cellular component | MEFV, DYNLL1, SHTN1, FNTA, PXN, STAU1, RABGAP1, DCTN3, MAP4, RP1, KIF1B, DCX, APPBP2, MAP2, MAP1S, GABARAP, PEA15, ACTR1A, TBCB, EML2, HDAC6, EML1, MID1, FNTB, TRIM54, DYNLL2, CLIP2, MAP1B, TTBK1 |
| microtubule cytoskeleton | cellular component | CCNB2, MAPK3, MAPK1, AKT1, WDR11, GAPDH, PMS2, CDC7, TUBB3, 39326, 41153, DNM1L, KIF3B, MAST2, ADCY10, KATNB1, RASSF1, KIF3A, CCNA1, SPAG1, SHTN1, KIF5B, VPS41, CENPE, SEPTIN2, KANK4, KIF17, TUBGCP4, SEPTIN9, SEPTIN10, IQGAP1, PPP2CA, MAP7D1, NAV1, THAP6, LYST, ENKD1, CRYAB, KIFAP3, MAPRE3, DVL1, HMMR, ARL2, KLHL22, FAM83D, MID1IP1, MAP4, ZNF397, ARL3, CEP131, CLIC4, PRC1, NEIL2, DNM3, OPA1, ZNF415, RBM39, SARM1, NUDCD2, DCDC2, TPX2, MX1, DST, TAF1A, DTNBP1, CDC42EP2, CXCR2, VAPA, SHMT2, PLK1, KIF2B, AGBL5, CKAP2, CDC42EP4, SRA1, TBCA, MAP9, KIF20B, MFN2, CLIP1, MAP1S, IFT43, FER, KIF18A, PKNOX2, MTUS1, MYCBP2, TAOK1, GAS2L3, PIK3R4, CHP1, KLHL4, HYPK, SLAIN2, GTF2F2, ACTR1A, CKAP5, BMERB1, TBCB, TUBA1C, ESRRA, SPTAN1, MAPRE1, TUBA3E, SEPTIN11, SPRY2, EHD2, EML1, MID1, POLR2C, MX2, SEPTIN1, NDRG1, SEPTIN5, GAS8, PSRC1, SKA1, APC2, HOXC8, ACTR1B, DNM1, RUSC1, FES, PPP2R1A, SEPTIN8, TUBG2, TTLL3, TMEM250, ATXN7, MARK4, MCM2, IQCB1, SEPTIN14, CDH26, CCSER2, MARK1, MAP7D3, SPAST, SEPTIN3, NUAK1, SEPTIN7, CENPV, P |
| microtubule end | cellular component | CAMSAP2, SPRY2, NAV3, KIF18B |
| microtubule organizing center | cellular component | BRCA2, NDRG2, CDK1, CCNB1, MAPK1, CASP8, CIB1, NR3C1, CTNNB1, GNAI1, ODF2, BRSK2, YES1, G6PD, MAK, CDC42, CDC20, PLA2G6, NPHP4, KATNB1, RASSF1, LRWD1, XRCC2, OFD1, CCT5, CCT4, RPS7, HNRNPU, IFT88, CAMK2B, PCM1, EFHC1, MZT2B, BLOC1S2, CEP57, CEP112, CEP20, CCDC113, HAUS2, BCCIP, KIF17, TUBGCP4, RTRAF, KIF2A, DDX3X, EVI5, NPM1, CETN2, CSNK1A1, CCDC14, CCDC38, NEK8, CIR1, MIB1, EHBP1, CEP70, NEIL1, TSG101, BBS2, PHF1, CCP110, DYRK3, CDC16, CEP55, DCAF12, CCDC81, NEDD1, NEK1, RNF19A, GNAI2, NUBP1, CEP350, BBS5, NIN, SPDL1, CEP41, HAUS4, KATNA1, TCP1, RASSF7, DYNC2LI1, RPGR, ENTR1, MAPRE3, ARL2BP, SNX10, BUB1B, TACC1, TNKS, ARL2, NUP62, PTK2, CETN1, MLLT11, CCDC96, KLHL22, SPECC1L, TPGS1, RBBP6, RAB11FIP4, C7orf31, MASTL, CDK5RAP2, DTL, RABGAP1, ARFGEF2, ROCK2, DCTN3, HAUS5, GNAI3, CEP85, CDK5RAP3, MKKS, WDR35, WRAP73, TACC2, ARL3, BBS9, AJUBA, DISC1, CEP131, CLIC4, CCDC66, CEP43, IST1, KIAA0753, KIZ, CEP120, POC5, MCPH1, TTC8, TOPBP1, C10orf90, KIFC1, CHMP1A, KRT18, UNC119, SGO1, CCDC141, SIRT2, NUDCD2, PIBF1, LR |
| microtubule plus-end | cellular component | MAPRE3, CDK5RAP2, MYO5A, DST, GAS2L1, CLIP1, CLIP4, NUMA1, SLAIN2, KNSTRN, CKAP5, TBCB, MAPRE1, GAS2L2, KIF18B, CLASP1, NCKAP5L, CLIP2, NCKAP5, CLIP3 |
| microvesicle | cellular component | DEFB1 |
| microvillus | cellular component | TGFB1, EZR, OXTR, AQP5, CA2, DCXR, ATP6V1B1, ATP6V1B2, BBS2, IQGAP2, VCAM1, CTSV, SLC9A3R1, JAM3, ATP6V1E1, FOXA1, CLIC4, ATP6V1A, TEK, USH1C, MYO6, PDGFA, ANGPT1, FSCN3, STARD10, ESPN, CNP, MSN, MYO1B, RDX, CRB1, ATP7A, EXOC4, HYAL2, PODXL, AOC3, RAPGEF3, SPN, PLEKHG6, MYO1C, PDGFRA, PTPRH, KIF13B, SLC27A4, MYO7A, MYO7B, ENPP7, PROM2, MYO1G, FSCN1, MYO1D, CBLIF, FMN2, WWOX, VIL1, LRRK2, SLC10A2 |
| microvillus membrane | cellular component | CTNNB1, ITGAV, EZR, SLC9A3R1, SCARB1, CA9, ITGB3, SLC26A2, MSN, S100P, PODXL, PDPN, CEACAM1, CDHR5, SYTL1, PTPRH, PROM2, MUC20, CDHR2, DPEP1 |
| midbody | cellular component | AURKC, BIRC5, CDK1, GNAI1, HSPA5, MAK, CDC42, 39326, 41153, KIF3B, RNF8, ANXA2, USP8, KATNB1, HNRNPU, CENPE, ABRAXAS2, SEPTIN2, KIF20A, MYH10, KEAP1, SCCPDH, ARL8B, LYRM1, IQGAP1, CEP55, SVIL, GNAI2, PIN1, SH3GLB1, CIAO2B, KATNA1, HSP90B1, BCL3, RACK1, URB2, UHMK1, TBCK, ENTR1, CHMP4A, MAPRE3, ARL2BP, TACC1, LAP3, KIF14, RAB11FIP4, CTNND1, DCTN3, GNAI3, ASPM, ARL3, CHMP4B, CLIC4, PRC1, IST1, GEM, PIK3C3, ANLN, RCC2, SIRT2, CENPF, DEFA5, DTNBP1, PKP4, KATNBL1, ANXA11, PKN2, MICAL3, MITD1, PLK1, TTC23L, AGBL5, EXOC3, WIZ, RALB, RAN, SPART, MAP11, KIF20B, CYLD, MBD5, SHCBP1, CEP44, ECT2, EXOC5, YPEL5, ARL8A, CEP126, JTB, RDX, TTC28, BIRC6, UVRAG, PITPNM1, TXNDC9, C6orf89, FLCN, TRIOBP, VPS37B, DCDC1, CENPC, TTLL12, ZFYVE26, ANKRD54, CHMP4C, LZTS2, ALKBH4, KIF4A, ERH, CDCA8, TTC19, SEPTIN1, SSH1, RAP2A, PKN1, PSRC1, MPLKIP, ZNF330, RAB8A, KIF23, DDX11, MTCL1, APC2, MICAL1, CCDC124, PTCH1, PDXP, RAB11FIP3, CRMP1, AURKB, MARK4, NAT10, INCENP, TOPORS, CTDP1, NEK2, KIF13A, KLHL9, SPAST, GDI1, SEPTIN7, CHMP1B, CENPV, |
| MIS12/MIND type complex | cellular component | MIS12, DSN1, NSL1, PMF1 |
| Mis6-Sim4 complex | cellular component | CENPO |
| mismatch repair complex | cellular component | MSH4, MSH5, PMS2, MLH3, MSH2, PMS1, MSH6 |
| mitochondria-associated endoplasmic reticulum membrane | cellular component | CANX, RAB38, PDZD8, RAB32, SERAC1, ZFYVE1, STX17, CLCC1, ATG5, TOMM20, ACSL4, TMEM41B, MBOAT7, TMX2 |
| mitochondrial alpha-ketoglutarate dehydrogenase complex | cellular component | BCKDHB, BCKDHA |
| mitochondrial ATP-gated potassium channel complex | cellular component | CCDC51, ABCB8 |
| mitochondrial crista | cellular component | STAR, ATPSCKMT, OPA1, LYN, PTPN1, SLC8B1, COX6B2 |
| mitochondrial crista junction | cellular component | MICOS13 |
| mitochondrial degradosome | cellular component | SUPV3L1, PNPT1 |
| mitochondrial DNA-directed RNA polymerase complex | cellular component | POLRMT |
| mitochondrial endopeptidase Clp complex | cellular component | CLPX |
| mitochondrial envelope | cellular component | CIDEA, BNIP3L, HSD17B8, ADAP2, HADHB, SDHD, UCP1, COX5B, BNIP3, TOMM20, SLC25A14, ABCB6, FKBP8 |
| mitochondrial fatty acid beta-oxidation multienzyme complex | cellular component | HADHA |
| mitochondrial inner membrane | cellular component | CYP24A1, CYP11A1, MGST1, HSD3B1, CYP11B1, ACAT1, HSD3B2, STAT3, VDAC2, GSTK1, SRC, PPOX, CYCS, HSPD1, CYP11B2, COX10, MT-CO1, MT-CO3, MT-ATP6, MT-ATP8, COQ10A, MT-CYB, MT-ND4, VDAC1, SDHB, SDHA, MRPS14, PMPCB, NDUFC2, MT-ND5, ATP5F1C, ATP5PO, DAP3, NDUFA6, MRPS15, MRPL20, PARL, MRPL47, TIMMDC1, MRPL17, MRPL22, TMEM14C, NDUFB9, NDUFA4, COX7A2L, NDUFB5, NDUFS6, NDUFB6, TYMS, ATP5F1B, MRPL3, SLC25A4, COX7C, ATP5PB, UQCRFS1, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, NDUFAF2, COA8, DMAC2L, COA1, GHITM, SPHK2, MRPL16, SIRT5, HIGD1A, MRPS23, MPC1, CLPX, UQCRB, COX5A, HCCS, ETFDH, MRPL14, ACAD11, TMEM126B, MRPL43, MAIP1, SLC25A38, PTCD3, RAB5IF, MRPL46, COQ10B, SLC25A13, MRPS17, NDUFAF1, NDUFC1, COQ9, MPC2, CKMT2, ATP5PF, UQCRC2, FECH, CPS1, ATP5F1E, MRPL49, ATAD3B, NDUFAF5, COX7B2, SLC25A43, DNAJC30, SLC25A33, MRPS30, ATAD3A, MRPS18A, MRPL39, MRPL15, TIMM9, NDUFS4, SCO1, ATP5PD, COX7A2, MRPL19, NDUFA8, MRPL58, MRPL51, SLC25A48, OMA1, MRPS24, ACAD9, TMEM14B, MRPL35, COQ3, MRPL27, COX11, ERAL1, NDUFB8, RPS3, COX7B, DHFR2 |
| mitochondrial inner membrane peptidase complex | cellular component | IMMP1L, IMMP2L |
| mitochondrial intermembrane space | cellular component | SOD1, PANK2, HSD3B1, HSD3B2, COA6, PARK7, CAT, PPOX, CYCS, COX17, SIRT5, AK2, TXNIP, PRELID1, CHCHD2, CAPN2, CIAPIN1, TIMM9, STAR, NDUFA8, PRELID2, ARL2BP, ARL2, REXO2, HAX1, HTRA2, CHCHD7, SUOX, STOML2, FBXL4, OPA1, NDUFS1, GATM, THOP1, BLOC1S1, TIMM8A, AIFM1, IMMT, PRELID3A, CEP89, PINK1, CLPB, TIMM13, SHMT2, COA4, TRIAP1, MICU2, NLN, THEM4, CHCHD5, GOLPH3, STMP1, PNPT1, SDHAF3, TIMM10B, LYN, TIMM8B, DIABLO, TRAP1, UQCC2, FGR, NDUFB7, TIMM29, TIMM10, PRELID3B, CHCHD10, MICU1, NME4, NDUFS5, DTYMK, GFER, AGK, MYOC |
| mitochondrial intermembrane space protein transporter complex | cellular component | TIMM9, TIMM13, TIMM10B, TIMM8B, TIMM10 |
| mitochondrial large ribosomal subunit | cellular component | MRPL20, MRPL47, MRPL17, MRPL22, MRPL3, MRPL16, MRPL14, MRPL43, MRPL46, MRPL49, MRPS30, MRPS18A, MRPL39, MRPL15, MRPL19, MRPL58, MRPL51, MRPL35, MRPL27, MRPL10, MRPL48, MRPL40, MRPL37, MRPL11, MRPL33, MRPL23, MRPL38, C12orf65, NSUN3, NDUFAB1, MRPL54, MRPL57, MRPL21, MRPL55, MRPL41, MRPL53, MRPL34, MRPL52, MALSU1, MRPL50, MRPL36, MRPL12, MRPL4, MRPL44, MRPL24, MRPL28, MTERF4, MPV17L2, MRPL9 |
| mitochondrial matrix | cellular component | SOD1, TP53, BRCA1, SOD2, GSR, NR3C1, CYP11A1, GPX1, ACAT1, DECR1, PARK7, GSTK1, C1QBP, APOA1BP, HSPD1, HSPA1L, MCL1, ARG2, HIBADH, PMPCB, FARS2, MLYCD, GLUD1, ACADM, ATP5F1C, PDK4, IBA57, LYRM7, GLRX5, ISCA2, TDRD7, NUBPL, GFM1, GRPEL1, TYMS, PCCA, ATP5F1B, MTHFD2, BCKDHB, GLDC, GCSH, ATP5PB, SSBP1, KARS1, PDK3, FXN, NADK2, LACTB2, HIBCH, MTERF1, ISCA1, ACSS3, SIRT5, LIPT1, CLPX, PDHA1, MDH2, GRSF1, DHRS2, ETFDH, HADH, SUPV3L1, MAIP1, TRNT1, NUDT9, TFB2M, NDUFAF1, FECH, SHC1, CPS1, ATP5F1E, OGDH, D2HGDH, RPUSD4, MCEE, ABHD10, DIMT1, PTCD1, ECHS1, GLUD2, SUCLG1, MRPL58, CLPP, OXCT2, PPA2, COQ3, SUCLA2, ARL2BP, ERAL1, NDUFB8, RPS3, IVD, ARL2, GLYAT, DARS2, NDUFAF7, DHFR2, ALKBH7, SARS2, ACP6, IARS2, MTRF1L, REXO2, SIRT4, NDUFS2, HARS2, TRMT5, RPUSD3, MTHFD1L, CBR4, MRRF, NMNAT3, GLRX2, AASS, ETHE1, AK4, ACAA2, AUH, PCK2, THEM5, NAT8L, HSD17B8, PYCR2, MMAB, MCCC1, ACO2, ELAC2, CARS2, PDHX, LIAS, PC, ATP5F1D, CA5A, SUOX, FASTK, ACAD10, PDSS2, MCAT, DUSP21, POLG2, FDX1, NDUFS1, MTHFS, NUDT2, BLOC1S1, RNASEL, TRMT1 |
| mitochondrial membrane | cellular component | BCL2, BAX, BAK1, BCL2L2, CYP11A1, CLU, HSD3B1, CYP11B1, HSD3B2, PPOX, CYP11B2, COX10, MT-ATP8, MT-ND4, DMPK, ACADM, NDUFA6, LYRM7, TIMM21, CCDC90B, PNPLA8, TIMMDC1, TMEM14C, NDUFB6, ATP5F1B, RMDN3, HIGD1A, FZD9, OGT, ATP5MC3, ATP5MPL, ETFDH, ACAD11, TMEM126B, RAB11FIP5, SORD, OGDH, TMEM135, SLC25A33, REEP1, PLA2G4C, MAPK8IP1, FLVCR1, RNF144B, COQ8B, OMA1, ACAD9, TMEM14B, IVD, TMBIM6, BNIP1, ATP5MD, C19orf12, UBIAD1, GNPAT, HTRA2, ANXA1, UCP3, SLC27A3, AFG1L, NDUFA1, NDUFA2, ATPSCKMT, NAT8L, COX16, PEMT, ATP5MC1, IFI6, ATP5MC2, DNM3, TMEM14A, SNPH, OPA1, IKBKE, VRK2, RCC1L, MX1, HKDC1, TRAK1, UCP1, ATXN3, BID, STARD13, NDUFAB1, DEGS1, CALM3, HIGD2A, ACADVL, BNIP3, SLC9B2, ANTKMT, CYP27B1, PLN, ACADL, BECN1, RHBDD1, COX4I1, IFI27, UCP2, NDUFA9, SLC25A30, ACSL4, SLC25A14, LYN, CARD19, GPAM, BOK, NME2, SLC25A44, SFXN3, COX14, IFI27L2, SLC25A10, BCL2L1, MX2, FKBP8, ABHD6, SLC25A32, BIK, OXA1L, CRLS1, NRP1, MT-ND4L, MT-ND6, DNM1, SFXN2, NGRN, ABCB8, ABCD1, GRAMD4, NRGN, ATCAY, PLEKHN1, SFXN5, AGK, LRRK2, MAVS, ABCG |
| mitochondrial nucleoid | cellular component | TERT, HSPA9, VDAC2, POLG, VDAC1, MPG, ATP5F1B, SSBP1, MTERF1, CLPX, GRSF1, FASTKD5, SUPV3L1, TFB2M, CPS1, ATAD3A, LRRC59, FASTKD2, ELAC2, SLC25A5, HADHB, POLG2, TRMT10C, POLRMT, PRORP, SHMT2, HADHA, TEFM, LRPPRC, ACADVL, TUFM, MTERF2, DHX30, TFB1M, UQCC2, TFAM, LONP1, TOP1MT |
| mitochondrial outer membrane | cellular component | PGR, BCL2, BAX, BAK1, BCL2L2, CASP8, MGST1, MTOR, VDAC2, BAD, RAF1, GJA1, MCL1, DNM1L, CYB5A, MYO19, DAO, VDAC1, DMPK, PRNP, PPP2R2B, GK2, FUNDC1, GK, MIGA1, RMDN3, QTRT2, CYB5B, ATP5MC3, LETMD1, RAB11FIP5, MFF, NLRX1, SLC44A1, SH3GLB1, BCL2L11, RPS6KB1, RPS27A, TOMM22, CPT1A, DNAJC11, HAX1, ACSL3, ASS1, ACSL1, SLC25A46, PGRMC1, BNIP3L, RAB32, VPS13C, USP30, SAMM50, MTX2, VAMP1, HADHB, ATP5MC2, TOMM34, RSAD2, OPA1, TOMM70, LPIN1, SPATA19, RTN4IP1, PHB2, STARD7, MTX3, MTARC2, MTERF3, MARCHF5, ULK1, BID, SLC8A3, ARMCX2, MFN1, PINK1, TOMM5, AKAP1, TOMM7, NIPSNAP2, CNP, CNR1, BNIP3, TOMM20, SPART, MIEF2, ACSL5, CYP27B1, MFN2, ARMCX6, MLXIP, MIEF1, FIS1, STMP1, IFI27, RHOT2, MFI, MSTO1, ARMCX3, ACSL4, UBC, MTX1, RHOT1, GPAM, CISD1, BOK, PPP1R15A, CYB5R3, ATF2, HK2, EPHA4, UBA52, WASF1, TOMM6, RNF185, AGPAT4, EXD2, STING1, BRI3BP, BMF, ABCB6, MT3, BCL2L1, MOAP1, VAT1, COASY, MIGA2, MUL1, PGAM5, TIGAR, NME1, TRIM14, TOMM20L, FAM210B, PI4KB, PDE2A, FOXO3, UBB, CPT1C, BCL2L10, ACACB, CPT1B, SNN, TOMM40, BCL2A1, QTRT1, |
| mitochondrial outer membrane translocase complex | cellular component | TOMM22, TOMM70, TOMM5, TOMM7, TOMM20, TOMM6, TOMM20L, TOMM40 |
| mitochondrial permeability transition pore complex | cellular component | BAX, PPIF, SPG7 |
| mitochondrial processing peptidase complex | cellular component | PMPCB, UQCRC2, PMPCA |
| mitochondrial prohibitin complex | cellular component | PHB2 |
| mitochondrial proton-transporting ATP synthase complex | cellular component | MT-ATP6, MT-ATP8, ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, ATP5MPL, ATP5PF, ATP5F1E, ATP5PD, ATP5MD, ATP5MC1, ATP5F1D, ATP5MG, ATP5MF, ATP5ME, PPIF |
| mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) | cellular component | ATP5F1C, ATP5F1E, ATP5F1D |
| mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) | cellular component | MT-ATP8, ATP5PB, ATP5MC3, ATP5PF, ATP5PD, ATP5MC1, ATP5MC2, ATP5MG, ATP5MF, ATP5ME |
| mitochondrial proton-transporting ATP synthase, catalytic core | cellular component | ATP5F1B |
| mitochondrial proton-transporting ATP synthase, stator stalk | cellular component | ATP5PD |
| mitochondrial pyruvate dehydrogenase complex | cellular component | PDHA1, PDHB, PDK1, DLAT, PDK2 |
| mitochondrial respirasome | cellular component | COX7A2L, UQCRB, RAB5IF, COX7B2, COX7A2, COX7B, NNT, STMP1, SURF1, UQCRC1, UQCRH, OXA1L, COX7A1 |
| mitochondrial respiratory chain complex I | cellular component | PARK7, MT-ND4, NDUFC2, MT-ND5, NDUFA6, NDUFB9, NDUFA4, NDUFB5, NDUFS6, NDUFB6, NDUFAF1, NDUFC1, NDUFS4, NDUFA8, NDUFB8, NDUFS2, NDUFB10, NDUFA1, NDUFA2, WDR93, NDUFB1, NDUFS1, NDUFB4, NDUFA12, NDUFA5, NDUFAB1, NDUFA7, NDUFA11, DMAC2, NDUFC2-KCTD14, NDUFA3, NDUFV2, NDUFB11, NDUFA9, DMAC1, NDUFV3, NDUFB2, NDUFS8, NDUFB7, NDUFA10, FOXRED1, MT-ND4L, NDUFS5, NDUFS7, MT-ND1 |
| mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) | cellular component | SDHB, SDHA, SDHD, SDHC |
| mitochondrial respiratory chain complex III | cellular component | MT-CYB, UQCRFS1, UQCRB, UQCRC2, BCS1L, UQCRQ, UQCRHL, UQCRC1, UQCR10, CYC1, UQCRH |
| mitochondrial respiratory chain complex IV | cellular component | MT-CO1, NDUFA4, COX7C, UQCRFS1, COX5A, UQCRC2, NMES1, COX6A1, COX4I1, NDUFA4L2, COX6A2 |
| mitochondrial ribonuclease P complex | cellular component | TRMT10C, PRORP, HSD17B10 |
| mitochondrial ribosome | cellular component | MRPS14, DAP3, MRPS15, MRPL20, MRPL47, MRPS22, MRPL43, MRPL49, MRPL39, MRPL51, MRPL35, MRPL48, MRPL40, MRPL37, MRPL11, MRPS12, NDUFA7, MRPL57, MRPL34, CHCHD1, MRPL28, MTG1, MRPL9 |
| mitochondrial small ribosomal subunit | cellular component | MRPS14, DAP3, MRPS15, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, MRPS17, MRPS18A, MRPS24, MRPS7, MRPS18C, MRPS33, MRPS28, MRPS26, MRPS12, MRPS27, MRPS16, MRPS31, MRPS2, MRPS34, MRPS6 |
| mitochondrion | cellular component | SOD1, ESR1, TP53, CYP1A1, PGR, MMP2, BCL2, TNFRSF1A, CASP1, CASP4, HSD17B4, FKBP4, BAX, CYP24A1, BAK1, ESR2, BCL2L2, TERT, OGG1, SOD2, CYP17A1, CDK1, MTHFD1, MAPK3, MAPK1, AKT1, GSK3B, CASP9, E2F1, CASP8, CDKN2A, PANK2, GSR, GNRH1, NR3C1, CYP11A1, GPX1, GSTP1, PARP1, MGST1, CLU, HSD3B1, CYP11B1, ACAT1, HSD3B2, GPX4, HSPA9, STAT3, MTOR, VDAC2, HSPA2, PTEN, PRDX4, PON2, DECR1, COA6, BAD, PARK7, GSTK1, CAT, HSPA5, SRC, MAPK8, PPOX, POLG, CYCS, C1QBP, TXNDC8, APOA1BP, IDH1, RAF1, HSPA1A, HSPD1, GJA1, CYP11B2, COMT, YWHAQ, APEX1, HSPA1L, PTPN11, MCL1, FOXO1, COX10, CYP1B1, TXNDC2, DNM1L, PLA2G6, CYB5A, MT-CO1, MT-CO3, MT-ATP6, MT-ATP8, ARG2, PRDX1, MYO19, PACRG, COQ10A, ADCY10, TP63, THG1L, 38231, MT-CYB, MT-ND4, ANXA6, VDAC1, SDHB, MPG, SDHA, HIBADH, DYNLL1, DMPK, MAPK14, PRNP, CIDEA, MRPS14, PMPCB, NDUFC2, FARS2, MLYCD, GLUD1, MT-ND5, ACADM, ATP5F1C, ATP5PO, DAP3, NDUFA6, MRPS15, LACTB, PPP2R2B, COX17, TFDP1, GK2, NBR1, PDK4, IBA57, LYRM7, ETFRF1, BLOC1S2, CFAP91, GLRX5, ISCA2, YRDC, FUNDC1, NUBPL, DDX1, GLYATL1 |
| mitotic checkpoint complex | cellular component | BUB3 |
| mitotic cohesin complex | cellular component | SGO2, DDX11 |
| mitotic spindle | cellular component | CDK1, MAPK1, MAK, CDC42, RANGAP1, DYNLL1, TADA3, HNRNPU, EFHC1, HECW2, RTRAF, NUSAP1, ESPL1, CEP170, NIN, TBCK, RMDN2, RPS3, NUP62, KLHL22, FAM83D, MAP4, WRAP73, GEM, KIFC1, PKD2, SIRT2, NUDCD2, DCDC2, TPX2, DIAPH1, PKP4, KATNBL1, ODAM, CXCR2, TACC3, MAD2L1, KIF2B, AGBL5, IKBKG, MAP9, MAP11, CDC14B, ECT2, MAD1L1, NUMA1, FAM161A, CLTC, TFDP2, KNSTRN, TPR, FLCN, DCDC1, HDAC3, TBL1X, NCOR1, EML2, CAPG, KDF1, TAF1D, EML1, CLASP2, SPOUT1, CKAP2L, KAT2A, SKA1, PKHD1, KIF23, EML4, AAAS, TPPP, EML3, CCSAP, NGRN, GOLGA2, SLC34A1, CLASP1, YEATS2, EPB41, IQCB1, KIF11, KIF22 |
| mitotic spindle astral microtubule | cellular component | DYNLT3, NUMA1, KIF18A, CCSAP, KIF18B |
| mitotic spindle astral microtubule end | cellular component | MAPRE3, MAPRE1, MISP |
| mitotic spindle microtubule | cellular component | HNRNPU, CEP295, CLTC |
| mitotic spindle midzone | cellular component | HNRNPU, CENPE, CTTN, PRC1, RCC2, MAP9, KIF20B, NUMA1, KIF18A, OR2A4, EML1, KIF18B, AURKB |
| MKS complex | cellular component | TMEM17, TCTN2, TCTN1, AHI1, B9D1, TMEM107, TMEM67, CEP290, B9D2, CC2D2A |
| MLL1 complex | cellular component | MAX, ASH2L, TEX10, HCFC2, RBBP5, RUVBL2, HCFC1, WDR5, PRPF31, INO80C, TAF7, PELP1, TAF1, KMT2A, SENP3, KANSL1, PHF20, RUVBL1, E2F6, TAF6, TAF4, MGA, MCRS1, CHD8, TAF9, RNF2 |
| MLL3/4 complex | cellular component | DPY30, ASH2L, KDM6B, RBBP5, WDR5, KMT2D, UTY, KMT2C, DYDC1, PAGR1, PAXIP1 |
| MLL5-L complex | cellular component | ACTB |
| MMXD complex | cellular component | ERCC2, CIAO1, CIAO2B, SLC25A5, MMS19 |
| molybdopterin synthase complex | cellular component | MOCS2 |
| Mon1-Ccz1 complex | cellular component | CCZ1B, CCZ1, MON1B, RMC1, MON1A |
| motile cilium | cellular component | HIF1A, CATSPER1, CATSPER2, AKAP4, GAPDHS, NPHP1, CABYR, LDHC, 41153, CATSPER4, CATSPER3, CCDC103, SPAG16, TEKT4, ROPN1L, ADCY10, TEKT2, 38231, SPA17, CFAP69, IFT88, SEPTIN2, CFAP70, CFAP65, CFAP91, MNS1, WDR19, PMFBP1, CEP20, QRICH2, DNAH2, DNAH17, CCDC65, IFT74, BBS2, ZBBX, SPATA6, IFT52, SORD, IQCD, CFAP36, CFAP300, CCDC181, FBXL13, DYNC2LI1, RPGR, OXCT2, DRC3, LYZL6, TPPP2, TPGS1, INTU, ANXA1, MKKS, DNALI1, SLC9C1, EFCAB2, IQUB, SPACA9, RSPH9, PKD2, BBS4, ABHD2, ARL13B, FSCB, IFT46, CEP89, CATSPERG, MROH2B, SAXO1, CFAP61, ROPN1B, RSPH6A, STARD10, ACTL7A, SLC9B2, CATSPERD, CABCOCO1, CFAP206, DNAH8, SLC25A31, IQCA1, CFAP73, SCNN1A, CFAP52, CFAP100, AK7, DRC1, CFAP20, GAS8, SPEF1, KLC3, ENKUR, GLI2, DNAAF5, IFT81, SEPTIN7 |
| MOZ/MORF histone acetyltransferase complex | cellular component | BRPF1, MEAF6, BRD1, KAT6A, ING5, KAT6B, BRPF3 |
| Mpp10 complex | cellular component | IMP3, IMP4, MPHOSPH10 |
| MPP7-DLG1-LIN7 complex | cellular component | LIN7C, LIN7A, MPP7, DLG1, LIN7B |
| Mre11 complex | cellular component | NBN, TERF2IP, MRE11, SP100, RAD50, MRNIP |
| mRNA cap binding complex | cellular component | FMR1, PIWIL1, NCBP2, NCBP1, RNMT, EIF4E, EIF4E2, CYFIP1, AGO2, EIF4E3, RAMAC |
| mRNA cap methyltransferase complex | cellular component | RNMT, RAMAC |
| mRNA cleavage and polyadenylation specificity factor complex | cellular component | CSTF2, TUT1, CPSF2, NUDT21, CSNK1A1, CPSF4, CPSF3, PIP5K1A, CPSF7, SSU72, ZC3H3, CPSF1, CPSF6, WDR33, SYMPK |
| mRNA cleavage factor complex | cellular component | NUDT21, PCF11, CPSF7, SCAF8, CPSF6, CLP1 |
| mRNA cleavage stimulating factor complex | cellular component | CSTF1 |
| MSL complex | cellular component | MSL3, MSL1, MSL2 |
| mucin granule | cellular component | VAMP8 |
| multi-eIF complex | cellular component | EIF3A, EIF2S1 |
| multimeric ribonuclease P complex | cellular component | POP4, RPP14, RPP38, POP1, RPP25, POP5, RPP21, POP7 |
| multivesicular body | cellular component | CD79A, GJA1, ACPP, CHMP2A, RAB11A, TSG101, CD74, CHMP5, BST2, VTA1, CTSL, CHMP4A, CHMP4B, ATP13A2, CHMP1A, CHMP6, SFTPB, CD63, CRHBP, NEDD4L, SORL1, LAMP1, SLC2A4, HDAC6, TPT1, CHMP4C, SFTPD, STEAP3, CHMP7, CST7, PRKAR1B, BACE1, CHMP3, CHMP1B |
| multivesicular body lumen | cellular component | SFTPB, SFTPC, CTSH, PGA5, NAPSA |
| multivesicular body membrane | cellular component | RAB27A, LAPTM4B, HGS, CD300LG, ATP13A2, RAB27B, CD63, NDFIP2, NSG2, SORL1, GIMAP5, NSG1 |
| multivesicular body, internal vesicle | cellular component | LAPTM4B, CD63, LRRK2 |
| multivesicular body, internal vesicle lumen | cellular component | EGFR |
| muscle cell projection membrane | cellular component | ARPC1A, PLEKHO1 |
| muscle myosin complex | cellular component | MYH7, MYH11, MYH1, MYL5, MYL6B, MYL3, MYH3, MYH6, MYH8, MYH13, MYH2 |
| muscle tendon junction | cellular component | NRAP, CIB2 |
| muscle thin filament tropomyosin | cellular component | TPM1, TPM3, TPM4, TPM2 |
| MutLalpha complex | cellular component | MLH1, PMS2, PMS1 |
| MutSalpha complex | cellular component | MSH2, MSH6 |
| MutSbeta complex | cellular component | MSH2 |
| MWP complex | cellular component | WRAP73 |
| Myb complex | cellular component | LIN37 |
| myelin sheath | cellular component | SOD1, BCL2, ERBB2, HSP90AA1, ALB, ENO1, GNAO1, SRD5A1, HSPA9, VDAC2, HSPA2, HSPA5, MIF, PDIA3, CLDN11, EZR, CDC42, RAP1A, PGAM1, PRDX1, 38231, CA2, VDAC1, SDHA, GJC2, MPZ, CA13, PRXL2B, PMP2, CNTN2, SIRT2, ITPR3, GLUL, CALM3, CNP, MBP, SERINC5, TSPAN2, TUBB4A, MAG, MYO1D, GDI1 |
| myelin sheath abaxonal region | cellular component | ITGB1, SCRIB, CNP, DLG1, PRKCZ, EXOC4 |
| myelin sheath adaxonal region | cellular component | PTEN, ANXA2, CNP, STX4, MAG |
| myofibril | cellular component | MYH7, TWF1, TPM1, ABRA, SCO1, ANKRD2, CAPN3, PSMA6, MYH1, CALD1, ACTG1, MYBPC1, OBSCN, PDE4DIP, ANKRD23, TMOD3, TWF2, MYL2, MYOD1, ARHGEF25, SYNE2, TMOD4, MYH3, MYH6, LMOD2, SCO2, MYH8, TMOD1, CASQ1, LMOD1, MYH13, ANKRD1, MYH2, SMTNL1 |
| myosin complex | cellular component | MYH7, MYO19, MYO15A, MYH10, MYL6, MYH14, MYL12B, MYL12A, MYO5C, MYL4, MYH7B, MYH11, MYO3B, MYO5A, MYH1, CGNL1, MYO18A, MYO6, MYO9A, MYO1B, MYL5, MYO5B, MYO10, BMF, MYO1F, MYO3A, MYO16, MYL6B, CCDC102A, MYL2, MYO18B, MYO1C, MYH9, CGN, MYL3, MYH3, MYH6, MYO7A, MYO9B, MYO7B, MYO1G, MYH8, MYO15B, MYO1D, MYH13, MYH2 |
| myosin filament | cellular component | MYH7, MYOM2, MYH7B, MYH11, MYBPC3, MYH1, MYBPC2, MYBPC1, MYH3, MYH6, MYH8, MYOM1, MYH13, MYH2, MYBPH |
| myosin II complex | cellular component | MYH10, MYH14, MYL12B, LIMCH1, MYH9 |
| myosin II filament | cellular component | MYH10, MYH14, MYH9 |
| myosin V complex | cellular component | DYNLL2 |
| myosin VII complex | cellular component | MYO7A |
| NADH dehydrogenase complex | cellular component | MT-ND4L |
| NADPH oxidase complex | cellular component | NOX1, CYBB, NOXO1, NOXA1, CYBA, NCF1, DUOX2, NCF4, DUOX1 |
| nascent polypeptide-associated complex | cellular component | NACA, BTF3, NACA2, NACAD |
| NatA complex | cellular component | NAA16, NAA50, NAA15, NAA10 |
| NatB complex | cellular component | NAA20, NAA25 |
| NatC complex | cellular component | NAA35, NAA30, NAA38 |
| nBAF complex | cellular component | DPF3, SMARCA2, DPF1, SMARCA4, SMARCE1, ARID1B, SMARCD3, SMARCB1, SMARCC2, SS18L1, ARID1A, SMARCC1, SMARCD1, ACTL6B, DPF2 |
| Ndc80 complex | cellular component | NDC80, SPC24, SPC25, NUF2 |
| negative cofactor 2 complex | cellular component | DR1 |
| NELF complex | cellular component | NELFCD, NELFA, NELFE, NELFB |
| Nem1-Spo7 phosphatase complex | cellular component | CNEP1R1, CTDNEP1 |
| neurofibrillary tangle | cellular component | CLU, NEFH, PICALM, NEFM |
| neurofilament cytoskeleton | cellular component | SYNM |
| neuromuscular junction | cellular component | APP, ITGB1, NRG1, F2R, HDAC4, DES, MYH10, ANK3, RAPSN, SYNGR1, CHRNE, PTN, FCHSD2, UTRN, VAMP1, STXBP5, SYP, DLGAP4, CHRNB1, CAV3, POSTN, PSEN1, SLC8A3, STX1B, CHRND, KCNC4, DLG1, CDK5R1, UNC13C, UNC13B, CIB2, CXADR, TRIP4, EFNA2, DNAJC5, EPHA4, SPOCK1, DLG4, P2RX7, PPP1R9A, SYNGR2, EPHA7, SLC5A7, PSEN2, CDK5, SYNC, PDZRN3, MYH9, LAMA5, CDH15, SNTA1, LRP4, SYNGR4, UNC13A, SYNGR3, SV2A, DLG2, ASCC1, TBC1D24, STXBP5L, CHRNA1, CRKL, SYNJ2BP, NEFL |
| neuron projection | cellular component | SOD1, ESR1, FAS, PTGS2, FKBP4, FMR1, ESR2, HSP90AA1, MTHFR, CASP8, CIB1, GNRH1, APP, VIM, GNAO1, CLU, CTNNB1, PTEN, NSMF, PARK7, SRC, CALB2, CDC42, RAP1A, PICK1, ANK1, NF2, KISS1, PACRG, TP63, TIMP2, MT-ND5, GABRB1, PAM, KIF5B, CAMK2B, CAMK2D, PRRT2, NRSN1, KIF17, RAB21, STMND1, TRAK2, CHRNA5, SLC6A6, MYH10, GRM3, BBS2, KCNN3, BAIAP2, TNN, KIF1C, ATP6AP2, SLC6A2, IQGAP1, PPT1, SLC12A2, ANK3, ASIC2, ALS2, SNAP23, SIAH2, ADGRL1, KCNK2, GNB3, GABRA2, CHRNE, GRIN1, WASHC5, PIN1, ARHGEF7, SYT13, BAALC, C9orf72, PPP1R9B, RTN4R, FLRT1, RGS17, MAPK8IP1, RAPGEF2, NCAM2, CTSV, HTR3B, STAU1, PTPRF, RPS6KB1, HTR3A, STAR, RACK1, TMIGD1, ANKRD27, FAM126A, CACNG2, DVL1, ARPC5, FLNB, MPDZ, S100A4, GPM6A, STX3, KCNN1, KCNN4, PRKN, ASS1, MAP4, PGRMC1, ZWINT, BAG3, RIC3, GHSR, ATP13A2, TAOK2, STMN1, SYT1, VAMP1, CACNG7, ARF1, CHRNA2, LYPD6, MACO1, HOMER2, STMN3, MYO5A, SYT5, SNPH, FLRT2, KIF1B, CALB1, SYP, GABRG2, GABRB3, SLC1A3, CNTN2, FADD, CCDC141, FRMD7, RASGRP2, ANKS1A, RIT2, BCL11B, GLRA3, CHRNB1, ATF4, GABRA5, PSPH, CPEB |
| neuron projection branch point | cellular component | BAIAP2 |
| neuron projection membrane | cellular component | KCNC1, UNC5A |
| neuron projection terminus | cellular component | BAIAP2, DMD, MOB2, FLRT1, SCRG1, SYT1, MACO1, FSTL3, SYP, GAD1, BSN, PTPN9, GCH1, DLG4, MME, VTI1A, ATCAY, SLC32A1, UCHL1 |
| neuron spine | cellular component | SHANK2, HOMER1, DLG4, LRRC4, PALM, NTSR1, GRIA1, SHANK1 |
| neuron to neuron synapse | cellular component | ATP1A3, ATP1B2 |
| neuronal cell body | cellular component | SOD1, TGFB1, APOE, TGFB3, TNFRSF1B, FAS, SRD5A2, IL6ST, FKBP4, ESR2, APOB, CYP17A1, HSP90AA1, DNMT1, GSK3B, CIB1, SRD5A1, MTOR, IGF1, DPP6, BMPR2, NCOA2, CDC42, SOS1, TUBB3, NTRK1, INHA, KISS1, ADCY10, KATNB1, ANXA5, TIMP2, TAC1, AGFG1, IAPP, PAM, FUS, KCNAB1, EFHC1, GJC2, GLRX5, NRSN1, LSM1, TRAK2, COBL, CANX, MYH10, AKAP12, OLFM1, KCNN3, BAIAP2, TNN, SNCAIP, PPT1, FXR1, SLC12A2, ASIC2, ZNF385A, ALS2, RTN4, SLC38A7, SIAH2, KCNK2, CAPN2, WASHC5, ARHGEF7, PCP2, PPP1R9B, RTN4R, RAPGEF2, STAU1, CYBB, PTPRF, HTR3A, STAR, RACK1, PURA, PDE1C, DAB2IP, SH3GL2, ATXN10, VTI1B, INPP5F, DVL1, FLNB, ANXA3, EPHB2, GPM6A, CNN3, KCNN1, BRINP2, KCND3, CPLX1, KCNN4, CREB3, ASS1, GRK4, S100A5, BMPR1A, HCFC1, PDE1A, NRXN1, DENND1A, SLC38A1, GLRX2, PPARGC1A, PPP1R1B, PGRMC1, ENO2, NQO1, RAB5A, SLC1A4, RIC3, NEUROG1, ADNP, ATP13A2, KCND2, USH2A, DDC, CACNG7, PICALM, FZD3, HOMER2, MYO5A, SYT5, SNPH, DGKI, CALB1, HPN, CRH, CYBA, SLC1A3, CNTN2, FRMD7, PMM1, KREMEN1, FEZ1, KCND1, RBM8A, ELK1, RIN1, ITPR3, CNNM4, SLC38A2, PSD2, SHANK2, |
| neuronal cell body membrane | cellular component | TACR3, SLC6A2, FLRT1, DAB2IP, KCND2, HPCA, GABRA5, ATP1A3, KCNC4, KCNB1, ADCY8, CX3CR1, KCNA2, ATP2B1, CD22, SLC4A8, THY1, KCNC1, KCNC2, AMIGO1, RGS8, SLC6A3, UNC5A, KCNC3, KCNE3 |
| neuronal dense core vesicle | cellular component | NPY, DMXL2, OPRD1, SCG2, KIF1A, STXBP5L |
| neuronal dense core vesicle lumen | cellular component | PENK |
| neuronal dense core vesicle membrane | cellular component | CADPS, KIF1A |
| neuronal ribonucleoprotein granule | cellular component | FMR1, UHMK1, PQBP1 |
| neurosecretory vesicle | cellular component | GNRH1 |
| new growing cell tip | cellular component | GRM6, TRPM1 |
| NF-kappaB complex | cellular component | RPS3, RELA |
| NF-kappaB p50/p65 complex | cellular component | RELA |
| NLRP1 inflammasome complex | cellular component | CASP1, NLRP1, PYCARD |
| NLRP3 inflammasome complex | cellular component | CASP1, CASP4, DDX3X, NLRP3, CARD8, PYCARD, DHX33, GSDMD |
| NLS-dependent protein nuclear import complex | cellular component | MYBBP1A |
| NMDA selective glutamate receptor complex | cellular component | GRIN1, EPS8, GRIN2C, GRIN2B, GRIN3A, GRIN2A, GRIN3B, SHANK1, GRIN2D, PTK2B |
| Noc1p-Noc2p complex | cellular component | NOC2L |
| Noc2p-Noc3p complex | cellular component | NOC2L |
| Noc4p-Nop14p complex | cellular component | NOP14, NOC4L |
| node of Ranvier | cellular component | ANK3, CNTN2, KCNQ3, SCN1B, KCNQ2, DLG1, SCN2A, NFASC, SCN1A, SPOCK1, DAG1, SPTBN4, BIN1, MYOC, SCN8A |
| non-motile cilium | cellular component | CFAP69, IFT88, SEPTIN2, PCM1, WDR19, SEPTIN9, RPGRIP1, GPR83, AHI1, TTC8, PKD2, DNAAF4, BBS4, PKD2L1, ARL13B, CEP89, MCHR1, TUBG1, HYLS1, IFT122, DRD1, SSTR3, RAB8A, DRD2, ANO2, GALR3, GLIS2, SEPTIN7 |
| nonhomologous end joining complex | cellular component | LIG4, XRCC5, DCLRE1C, XRCC6, PRKDC, XRCC4, PAXX, NHEJ1 |
| NOS2-CD74 complex | cellular component | CD74 |
| npBAF complex | cellular component | SMARCA2, ACTL6A, SMARCA4, SMARCE1, SS18, SMARCD3, SMARCB1, SMARCC2, PHF10, ARID1A, SMARCC1, SMARCD1 |
| NSL complex | cellular component | KANSL1L, KANSL2, KANSL1, KANSL3, MCRS1 |
| NuA3a histone acetyltransferase complex | cellular component | MEAF6 |
| NuA3b histone acetyltransferase complex | cellular component | MEAF6 |
| NuA4 histone acetyltransferase complex | cellular component | ACTB, MORF4L2, EPC2, MORF4L1, ACTL6A, MRGBP, YEATS4, DMAP1, RUVBL2, MSL3, ING3, KAT5, RUVBL1, EPC1, MEAF6, BRD8, ACTL6B, EP400 |
| nuclear aryl hydrocarbon receptor complex | cellular component | AHR |
| nuclear body | cellular component | TP53, MDM2, CDKN2A, SUMO1, MED7, CSTF2, TCF7, EIF2D, NBR1, RNF34, LPAR4, ZNF350, NMNAT1, SENP2, TERF2IP, KLHDC2, KIF2A, NUDT21, COIL, ELF2, HIKESHI, SRCAP, SUGP2, ZC3H8, NSMCE2, UIMC1, TRIM4, DBF4, DRG1, AIRE, ZIC2, RPA2, VIRMA, NUDT9, DSN1, ZBTB4, MSRA, HCFC2, ATMIN, HOXD3, STK4, SP140, TRIM25, CREBRF, MINDY1, NELFA, INTS7, SLTM, ARIH1, NCAM2, ATRX, YARS1, ICE2, ESRP1, GTF3C6, GNL3, FANCD2, SUDS3, BAZ1B, SAP18, TNKS, PCGF2, LSM11, SUZ12, SETX, KCTD13, CENPI, CENPT, USP28, SH3BGRL3, PTPN23, RETREG1, NOP10, BPNT2, NSMCE4A, CREB3, NFATC1, CLK2, DCAF7, GTF2B, FAAP20, CREBBP, TOE1, POLK, ZWINT, TARBP2, RAB8B, ITPA, BABAM1, BHLHE40, NELFE, PLEKHH2, TOPBP1, TINF2, WRAP53, SCRT1, MKNK2, ZBTB20, FANCL, ORC3, EXO1, UBXN7, CCNDBP1, SKI, UBE2I, ZFHX3, SGO1, ABRAXAS1, STK35, GEMIN6, HMG20B, TKT, DTX1, REXO1, DCLRE1B, LARS1, PARP3, SNAPC5, CLIC3, MKI67, LAGE3, PKN2, GEMIN5, EHMT1, SMAD6, GEMIN4, SATB1, GON4L, RAPH1, HIPK3, FBXL3, MAU2, ITGB1BP1, KLF11, SP100, BMI1, XRRA1, PCNP, YME1L1, PAPOLG, TOLLIP, HIPK2, HOXC10, ICE1, |
| nuclear cap binding complex | cellular component | NCBP2, NCBP1 |
| nuclear chromatin | cellular component | ESR1, TP53, AR, NRIP1, SP1, STAT1, UBE2B, E2F1, EZH2, MBD2, MBD1, MTA2, STAT3, MUC1, THRB, H2AFX, ACTB, MEF2A, H1FNT, NR1H3, TP63, TCF7L2, ZBTB5, SHOX, HOXA3, H1-4, HOXD13, NASP, IRX6, TFDP1, NR1D2, E2F5, NFXL1, H2AZ2, OLIG3, SETD3, ZFPM2, FOXJ3, KLF4, HOXD8, PAX7, HOXA6, DDIT3, SMARCA2, CEBPG, MAX, ISL1, CREB5, KLF9, TAF5, ELF2, E2F4, ZBED5, ZC3H8, DPF1, FOXJ1, PAWR, TIPIN, ZHX1, TBX10, NKX2-2, ACTL6A, SPI1, PBX2, RFX5, ESRRG, IRX1, NHLH1, POGZ, THAP6, ZNF385A, GATA5, CALCOCO1, HIF3A, USP3, HOXA2, PSIP1, HNRNPC, RARB, ATF1, HOXD3, RFX3, SMARCA4, SREBF2, TFCP2, NFX1, SMAD4, HNRNPD, HNF4G, ASXL2, ASXL1, BHLHE22, HDAC2, RSF1, PHOX2B, NEUROG2, THAP1, LHX3, KDM6B, EOMES, HOXA5, STAT5B, PPARD, APTX, H2AC12, NKX3-1, UBP1, MACROH2A2, FOXN3, HMGB3, HBP1, LYL1, ELF1, PCGF2, SOX18, BUD31, SP4, MXD1, ADNP2, IPO4, JDP2, CSRNP3, SMARCE1, ZNF414, NEUROD6, FEV, CSRNP2, ASCL3, NKX1-2, TCFL5, NCOA3, CREB3, NFATC1, HOXB5, H2AZ1, EGR1, PBX3, FOSB, FOXA1, NKX3-2, MYT1, BATF, ASCL4, SLX4, SPIC, CREBBP, EHMT2, ASCL2, EBF3, VSX1, N |
| nuclear chromosome | cellular component | BIRC5, MSH4, REC8, TOP2A, TOP1, HIST1H4A, HNRNPU, IK, TERF2IP, EXOSC9, ATRX, SETX, SMARCE1, HDAC8, TIMELESS, HMGA2, SMARCB1, NIPBL, PBRM1, MACROH2A1, BLM, H3C1, NCAPD2, FIGNL1, SPIDR, PINX1, SMC2, H3-3A, H4-16 |
| nuclear chromosome, telomeric region | cellular component | LIG4, BRCA2, TERT, CDK1, ERCC1, ATM, PARP1, ATR, PCNA, APEX1, NBN, MSH2, HIST1H4A, MCM3, TERF2IP, ORC5, WDR82, XRCC5, RPA2, FEN1, CBX1, CBX3, THOC3, THOC7, THOC1, SSB, ATRX, PURA, MACROH2A2, TNKS, RPA1, SLX4, POT1, NHP2, POLR2B, ORC1, UPF1, DCLRE1C, PPP1CB, TINF2, ORC3, XRCC6, ORC2, H2BC3, DCLRE1B, MEN1, MRE11, CDC73, ALYREF, TNKS2, SP100, TERB2, THOC2, MCM5, PRKDC, NABP1, ORC4, MACROH2A1, THOC5, SMCHD1, PML, LRIF1, ACD, TP53BP1, RAD50, ERCC4, WRNIP1, HAT1, RAD51D, HMBOX1, MCM4, MCM7, DCLRE1A, STN1, MCM6, H2AC1, NABP2, CBX5, PPP1R10, THOC6, NLRP2, SUN2, POLD1, TFIP11, XRCC3, MCM2, PINX1, NAT10, H3-3A, DDB1, ZSCAN4, H4-16, GAR1 |
| nuclear cohesin complex | cellular component | RAD21 |
| nuclear condensin complex | cellular component | NCAPD3, NCAPH, SMC4, NCAPD2 |
| nuclear cyclin-dependent protein kinase holoenzyme complex | cellular component | BCCIP, CDK13, CDK12 |
| nuclear envelope | cellular component | PTGS1, BAX, MAPK3, PARP1, NSMF, SLC22A18, RANGAP1, GMCL1, GABRB1, ALOX5AP, EMD, LBR, NUP93, MNS1, UBXN4, TERF2IP, PGRMC2, CHMP2A, CETN2, TOR1AIP1, CNEP1R1, NUP37, CUSTOS, NUP85, DDX19B, ANXA7, NUP107, NUCB2, CBX3, DHRS2, NUP43, POM121, RBM15, RTN4, IPO11, MTMR6, MGST3, NUP35, NELL1, MGST2, NUP58, PLA2G4C, XPO1, ZMPSTE24, CYBB, SEC13, NUP205, IPO9, RTCB, NEMP1, NUP62, BNIP1, HAX1, IPO8, BNIP2, ATRAID, LEMD2, LRRC59, BNIP3L, NUP155, GNAZ, CHMP4B, OTULINL, S100A6, IST1, RAB40B, EBP, TOR2A, FANCL, LMNB1, UBE2I, LPIN1, MLIP, RNF43, VRK2, FAM156A, MTMR8, TNPO3, MCM3AP, CENPF, RAE1, DST, NAPEPLD, PLPP7, SEH1L, ANXA11, GOLT1A, PARP16, TNKS2, FAM169A, CETN3, TMPO, PTGER3, RAN, BNIP3, GLE1, NUP133, HTATIP2, TRPC7, AGPAT3, RRM1, CLIP1, CSE1L, AHCTF1, OSBPL6, MAD1L1, RAC2, IFI27, NRM, BICD2, TMEM170A, IPO7, ALOX5, PLA2G4A, PRKCZ, PARP6, NUP54, WDFY3, NXF1, NPC1, TPR, RANBP2, NUP98, ITPR1, FAF1, CLIC1, LTC4S, RBM15B, ROGDI, TOR1B, SREBF1, LMNB2, ABCF1, MYOF, PARP8, CHMP7, SMPD4, SYNE4, GHDC, SYNE2, SIGMAR1, TOR4A, CTDNEP1 |
| nuclear envelope lumen | cellular component | APP, IGF2R, PLAAT1, CCAR1, BCHE, TUBB, CACYBP, PTGES, ALOX5, SORL1 |
| nuclear euchromatin | cellular component | CTNNB1, NSMF, RBMX, H1-4, TCF7, TRIM24, KLF4, ASH2L, CBX3, RUVBL2, H2AZ1, PPARGC1A, H1-2, NR1H4, SETD5, H1-0, H1-5, ID2, POU4F2, MYOD1, H1-1, H1-3, ALKBH1 |
| nuclear exosome (RNase complex) | cellular component | EXOSC10, MTREX, EXOSC9, MPHOSPH6, EXOSC7, EXOSC5, EXOSC1, EXOSC3, C1D, EXOSC8, DIS3, WDR74, EXOSC4, NVL, EXOSC6, EXOSC2 |
| nuclear heterochromatin | cellular component | H1-4, CBX1, CBX3, PSIP1, TCP1, ATRX, H2AZ1, SIRT2, SATB1, UHRF2, UHRF1, H1-5, KMT5C, CBX5, FOXC1, TNKS1BP1 |
| nuclear inclusion body | cellular component | NBN, STUB1, NUP153, ATXN3, ATXN1, SLF1, NXF1, TPR, RANBP2, NUP98, PABPN1, RAD18 |
| nuclear inner membrane | cellular component | DPY19L2, MATR3, EMD, LBR, TOR1AIP1, TMEM43, CBX3, NPAP1, ZMPSTE24, NEMP1, TRA2B, DPY19L1, LEMD2, TMEM120A, LMNB1, ARL6IP6, GHRHR, MFSD10, FAM169A, LRPPRC, TERB2, ERN1, DPY19L3, DPY19L4, TMX4, ATP11B, LEMD3, RNF13, IFI27, UNC50, NRM, ITPR1, LMNB2, TM7SF2, PSEN2, NUTF2, SIGMAR1, SUN2, TMEM201, TMEM120B, SMAD3 |
| nuclear lamina | cellular component | NARF, PRR14, NUP35, STX1B, CASK, HLCS |
| nuclear lumen | cellular component | NARF, MLIP, SYNE2 |
| nuclear matrix | cellular component | TP53, OGG1, MBD1, NSMF, GMCL1, TEP1, MATR3, HNRNPU, SORBS1, ZNF350, JAK2, KIN, HNRNPM, ARFGEF1, PSPC1, CXXC1, SFPQ, DDX39B, THOC1, SMC3, AKAP8, YEATS4, HNRNPA2B1, MORC3, RUVBL2, DCAF7, RUNX1T1, PHF5A, SRPK1, MAEA, CLIC4, PSMA6, ERCC8, TINF2, CHMP1A, CFL2, LMNB1, RNASEL, NONO, PHB2, TGFB1I1, CENPF, GHRHR, LGALS13, MEN1, ATXN3, PRPF40A, ATXN1, SATB1, XPOT, RAD21, YY1, BASP1, PPIG, STAG2, STAG1, AHCTF1, NUFIP1, RUVBL1, NCOR2, ENC1, NUMA1, SCAF8, ALOX5, PML, PRKCZ, PRKCD, SNW1, SMC1A, LRIF1, UHRF1, CENPW, HAT1, BLM, GFI1B, ZNF326, CASK, KIF4A, ZNF703, KRT8, SRRM1, HLCS, PHACTR3, GFI1, PIAS4, AKAP8L, RGS12, ATXN7, CAD, DGKQ, KIF4B, SPTBN4, MORC2, PAXIP1, SATB2, DNTT, POLA1 |
| nuclear meiotic cohesin complex | cellular component | REC8, SMC3 |
| nuclear membrane | cellular component | EGFR, BCL2, HSD17B1, GAPDH, EDNRA, NSMF, PTGDS, PUM2, SUMO1, RANGAP1, H2BFWT, ANXA4, DMPK, KPNA4, PRNP, ALOX5AP, EMD, LBR, PCM1, NUP93, ERBIN, GTPBP4, QRICH2, SENP2, KLHDC2, CEPT1, PLRG1, GRK5, TOR1AIP1, CNEP1R1, RB1CC1, NUP85, MRPS23, SEPHS1, NUP107, TXNL4A, BRAP, ALG14, POM121, RBM15, NUDT9, PHF11, SH3BGRL2, JPT1, NUP35, C9orf72, NUP58, MINDY3, DNAJB12, FZR1, XPO1, MRPL19, WTAP, POMZP3, TEX2, NUP205, TMEM18, C2orf42, NUP50, NOS1AP, LYPLA1, TNKS, YEATS4, NUP62, DNAJC1, CMTM3, DTL, HAX1, CASC3, APEH, NRXN1, CCNI, LEMD2, AEN, NUP155, YBX1, IL15RA, DCTN5, TMEM38B, CCND1, NUP153, MACO1, SCAI, TBC1D20, RNF6, HPN, LMNB1, LPIN1, QSOX2, ZNF354C, PRPF38A, OSBPL8, AKIRIN1, MCM3AP, NDUFB4, MX1, NUDT1, TAF3, PRICKLE2, CLCC1, TXLNG, GTF3C3, ZBED1, ADRA1A, PSEN1, INTS2, VAPA, MYO6, EDNRB, RRP12, HACD3, EI24, ANKRD17, ITGB4, SLC29A2, GLE1, AK9, DNAJB14, NUP133, DNAJC2, ZNF224, PHF8, SLC30A1, SDCBP, TMEM97, TOR1AIP2, AHCTF1, CPNE1, PHF20, OSBPL6, SENP1, NPIPA1, LEMD3, ABL1, HOXA7, GNAQ, NRM, EPC1, ALOX5, PML, MPL, NUP54, WD |
| nuclear MIS12/MIND complex | cellular component | MIS12, DSN1, PMF1 |
| nuclear nucleosome | cellular component | H2BFWT, H1-4, H2AB1, CENPA, H3C1, H3-3A, H2AB2, H4-16 |
| nuclear origin of replication recognition complex | cellular component | LRWD1, ORC5, ORC1, ORC3, ORC2, ORC4, MCM2 |
| nuclear outer membrane | cellular component | DMPK, EMD, KASH5, NUCB2, UGT2B28, GUCY2F, GHRHR, ITPR3, PSEN1, LRPPRC, ITPRIP, CLMN, CPTP, BOK, LTC4S, RETSAT, GUCY2D, NAV3, SMPD4, NUTF2, SYNE4, SYNE2, SIGMAR1, DHCR7, SYNE1, TMEM109 |
| nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | RAB14, YIPF5, NPLOC4 |
| nuclear pericentric heterochromatin | cellular component | IKZF1, CBX3, ATRX, NCAPD3, CENPB, CENPC, CBX5, CENPA |
| nuclear periphery | cellular component | NUP93, NUP107, PSIP1, NUP205, ATF7, NUP153, EBNA1BP2, ATF4, MAP2, SP100, TPR, NUP98, DAG1, ANAPC4 |
| nuclear pore | cellular component | SUMO1, RANGAP1, AGFG1, NUP93, SENP2, CETN2, RGPD4, NUP37, NUP88, NUP85, ENY2, DDX19B, NUP107, NUP43, POM121, XPO4, NUP35, NUP58, NPAP1, SEC13, NUP205, NUP50, TNKS, NUP62, EIF5A, EIF5A2, KPNA3, NUP155, PCID2, NUP153, IPO5, MCM3AP, RAE1, SEH1L, POM121L2, NXT1, CETN3, XPOT, RAN, GLE1, NUP133, XPO7, AHCTF1, RANBP3, NPIPA1, NUP210L, BICD2, IPO7, RGPD2, KPNA1, NUP54, NXF1, SNUPN, TPR, RANBP2, NUP98, RANBP3L, MX2, NUTF2, MYO1C, AAAS, PARP11, NUP210, MVP, RGPD1, NUP188, RGPD8, NUP42, NUP214, NUP160, RGPD5 |
| nuclear pore central transport channel | cellular component | NUP35, NUP62, NUP153, NXT1, NUP54, NXT2, NUTF2 |
| nuclear pore cytoplasmic filaments | cellular component | RANGAP1, GLE1, RANBP2, NUP98 |
| nuclear pore inner ring | cellular component | NUP155, NUP188 |
| nuclear pore nuclear basket | cellular component | CETN2, ENY2, NUP35, PCID2, NUP153, MCM3AP, MAD2L1, CETN3, MAD1L1, TPR, RANBP2, NUP98 |
| nuclear pore outer ring | cellular component | NUP37, NUP85, NUP107, NUP43, SEC13, SEH1L, NUP133, AHCTF1, NUP98, NUP160 |
| nuclear pre-replicative complex | cellular component | ORC3, CDC45, WDR18 |
| nuclear proteasome complex | cellular component | PSMC5, PSMD12, UBQLN4 |
| nuclear replication fork | cellular component | PCNA, SMARCA5, BAZ1B, SMARCAL1, ZRANB3, MMS22L, ETAA1, SMARCAD1, WDHD1, TREX1, TONSL, ZMIZ2 |
| nuclear RNA export factor complex | cellular component | NXF2 |
| nuclear RNA-directed RNA polymerase complex | cellular component | TENT2, ZNFX1 |
| nuclear speck | cellular component | WT1, NRIP1, HIF1A, OGG1, SRY, MBD1, APEX1, CLK3, SUMO1, SRSF4, SRSF6, YLPM1, TCERG1, GLI3, HDAC4, HNRNPU, IK, TRIM69, DNAAF1, RNF34, S100PBP, ERBIN, WAC, TUT1, POMP, PLRG1, LPXN, PIAS1, SNRNP70, HOXA6, GRK5, IL15, CSNK1A1, DYRK1A, TRIP12, ZNF638, HIKESHI, ZC3H14, ZC3H18, CIR1, ZNF106, BCLAF1, CWC15, MORF4L1, DYRK3, DUSP11, SF3B1, SARNP, VIRMA, DDX46, COP1, NOC3L, SRSF12, PSPC1, THOC3, YTHDC1, RBM15, SRSF8, DHX36, ABITRAM, CXXC1, PRPF19, HIF3A, AP5Z1, PARN, SFPQ, MTREX, RBM25, RBM10, PIN1, DDX39B, THOC7, FNBP4, PNISR, SNRNP40, THOC1, SRRM2, LUC7L2, CDC40, PIAS2, SNRPB2, WTAP, ARL6IP4, PRPF18, STK17A, AK6, SAP18, OIP5, HBP1, SLU7, ELL, PCBP1, ZC3H13, NUGGC, RBBP6, SMC5, ATXN2L, RUFY1, FEV, C12orf57, RBM4B, COPS4, CWC25, CASC3, PRKN, PRPF6, CLK2, SART3, PHF5A, HIPK1, U2AF1L4, PRPF31, TOE1, EHMT2, SRPK1, EIF4ENIF1, BNIP3L, LUC7L3, SRPK2, TAB1, ASCC3, FYTTD1, REXO4, ACIN1, POLR2D, NDUFB1, SYF2, TAP2, PPP1R8, SF3B2, FAM76B, LHPP, SAP130, NRDE2, BMP2K, FBXL4, DHX15, NAMPT, SRSF3, MEF2C, RBM39, NONO, CTR9, ZNF830, PI |
| nuclear stress granule | cellular component | TIA1, RBFOX1, SYMPK |
| nuclear subtelomeric heterochromatin | cellular component | ATRX |
| nuclear telomere cap complex | cellular component | TERT, TERF2IP, XRCC5, POT1, TINF2, XRCC6, ACD |
| nuclear transcription factor complex | cellular component | SOX9, SRY, CTNNB1 |
| nuclear ubiquitin ligase complex | cellular component | BABAM2 |
| nucleoid | cellular component | TOP2A, SSBP1 |
| nucleolar ribonuclease P complex | cellular component | POP1, POP5, RPP21 |
| nucleolus | cellular component | TP53, ATF3, WT1, NRIP1, FMR1, TERT, HMOX1, WEE1, STAT1, MDM2, CDKN2A, BRWD1, CHD2, PARP1, HSPA9, TNP2, KAT7, LDOC1, C1QBP, LIN28B, PARP2, EZR, APEX1, SUMO1, XPC, 39326, TXNDC2, DROSHA, CHD7, VCY, TOP2A, NF2, PAFAH1B2, SRSF9, CAMK4, TAF4B, SIN3A, TSPYL1, NBN, MYC, TOP1, EXOSC10, UTP14C, MALT1, YBX2, SCD, NSA2, POP4, HSPA8, MCM3, RPL4, RPL3, RPL5, RPS10, TTC3, RPS3A, RPS7, RPS14, RPS6, EEF1A1, MRPS15, EWSR1, RBL2, PWP1, E2F5, POLR1F, DCAF17, RNF20, ZNF655, CDCA7L, LLPH, GTPBP4, TUT1, RPF1, POLR1B, SPATS2L, POLR1H, RSL24D1, NARF, NUB1, KIF2A, COX7A2L, REV3L, DKC1, RPP14, TYMS, NPM1, BCKDHB, COIL, HNRNPM, RPL7A, ADARB1, MRPS9, MORF4L2, PDK3, TAF5, SNAPC1, SHQ1, ZC3H14, WDR82, FBXO11, SLC30A5, BRIX1, TSG101, NUSAP1, DDX47, ZNF106, CUTC, IMP3, GNL3L, EIF3L, NOP58, ARFGEF1, PPP1R12A, HNRNPR, DIAPH2, PPM1B, PDHA1, XRCC5, RPL7, RPL13, FEN1, FXR1, MARS1, RPS13, RPL11, RPL19, NSUN2, LETMD1, AOPEP, NOC3L, PSPC1, ZNF385A, DSN1, TEX10, JPT1, MRTO4, SBDS, CPNE3, TULP3, PSIP1, SURF6, PARN, SRP19, CPS1, MTREX, RPS9, SMARCA4, |
| nucleolus organizer region | cellular component | SIRT7 |
| nucleoplasm | cellular component | NR5A2, SOD1, ESR1, PRM1, TP53, PGR, AR, VDR, HSD17B1, RAG1, ATF3, WT1, IGFALS, AHR, BRCA1, SOX9, NRIP1, LIG4, BRCA2, CASP6, SOX10, FKBP4, FMR1, CYP24A1, NR5A1, HIF1A, CMTM2, ESR2, NDRG2, TERT, BIRC5, OGG1, NR1I2, USP1, CCNB2, PRM2, CDK1, HSP90AA1, ERCC1, SP1, CCNB1, MGMT, ERCC2, XRCC1, FGFR2, XPA, DNMT1, MAPK3, MAPK1, WEE1, CDC25A, CDC25C, AKT1, HNF1B, SOX3, STAT1, CASP3, NR0B1, UBE2B, HSF1, MDM2, E2F1, SRY, ATM, STAT4, CASP8, EZH2, UBR2, CDKN2A, MBD3L1, CIB1, PEG3, MBD2, DNMT3B, MTRR, PLAGL1, CHD2, POLQ, MTA2, NR3C1, PARP1, CSNK2A2, CTNNB1, STAT3, MTOR, BAG6, RAD23B, PTEN, CSNK2B, DECR1, NSMF, KAT7, RB1, MIF, MLH1, MAPK8, PMS2, KHDRBS1, ATR, NCOA2, APOA1BP, XAB2, PARP2, CDC7, PDXK, HSPA1A, HSPA1B, THRB, PCNA, H2AFX, APEX1, HSPA1L, PPARG, GATA4, SOX2, CLK3, CDK9, ACTB, SUMO1, XPC, MEF2A, MCL1, FOXO1, CDC20, UAP1, DUSP6, DPP8, IL17RD, CLEC7A, DROSHA, CLOCK, BRD4, RNF8, TOP2A, HNRNPL, USF1, PSMA3, USP8, ETV5, KDM5C, SRSF4, NR1H3, SRSF9, SRSF6, CAMK4, PPIP5K1, TAF4B, TADA1, PRMT6, SIN3A, NPAS2, PYGO2, KDM5D, TP6 |
| nucleosome | cellular component | PRM1, PRM2, TNP1, TNP2, H2AFX, H2BFWT, HIST1H4A, H1-4, H2AZ2, SPHK2, H2BC21, H2AC12, MACROH2A2, H2AZ1, H2BC5, GLYR1, H2AJ, H2AC6, H2BC12, H1-2, H2AC7, H2BC3, H2AC20, H2AC21, H1-8, SOS2, HP1BP3, H2AC18, MACROH2A1, SLF1, H1-0, H2AB1, H2BU1, H2BC9, H1-5, H2BC17, H2AC11, H1-1, H2AC1, H4C7, H2BC15, H1-3, KAT6A, CENPA, H3C1, KDM1B, KAT6B, H2AC4, H3-3A, H2BW2, H2AB2, H4-16, H2BC10, H3C13 |
| nucleotide-activated protein kinase complex | cellular component | PRKAR2A, PRKAB1, PRKAG2, SESN2 |
| nucleotide-excision repair complex | cellular component | ERCC1, ERCC5, ERCC8, ERCC4, POLD1 |
| nucleotide-excision repair factor 1 complex | cellular component | ERCC1, XPA, ERCC4 |
| nucleotide-excision repair factor 2 complex | cellular component | XPC |
| nucleus | cellular component | NR5A2, DDX3Y, GNAS, SOD1, EGFR, TGFB1, APOE, ESR1, PRM1, TP53, PGR, MMP2, AR, BCL2, TGFB3, VDR, RAG1, ATF3, WT1, TNFRSF1B, PTGS1, BRD2, FAS, NOS3, PTGS2, AHR, BRCA1, SOX9, NRIP1, LIG4, BRCA2, SOX10, FKBP4, FMR1, BAX, CYP24A1, DAZ2, NR5A1, HIF1A, TSSK4, DAZ4, NOSTRIN, ESR2, TSSK6, DAZ1, DNMT3L, NDRG2, AURKC, FAM50B, TERT, BIRC5, OGG1, ZEB2, NR1I2, USP1, CCNB2, PRM2, ERBB2, CDK1, HSP90AA1, ERCC1, SP1, HMOX1, CCNB1, MGMT, ERCC2, XRCC1, HNF1A, FGFR2, FGFR3, XPA, DNMT1, MAPK3, MAPK1, TYK2, WEE1, CDC25A, CDC25C, AKT1, HNF1B, KDR, SOX3, STAT1, CASP3, CDKN2A, FASLG, TFPI2, GSK3B, NR0B1, CASP9, UBE2B, SNRPN, S100A12, HSF1, MDM2, E2F1, HSF2, SRY, ATM, KANK1, STAT4, EZH2, NFE2L2, BRDT, UBR2, CTCFL, MBD3L1, CIB1, RNF17, USP26, WDR11, PEG3, ARNT2, BRWD1, MBD2, DNMT3B, MBD1, PLAGL1, DMRT1, CHD2, MGEA5, POLQ, MTA2, ALB, NR3C1, KRT1, GAPDH, HSPB1, ENO1, KLK3, MSMB, GSTP1, TNP1, PARP1, CBSL, MGST1, CLU, FGFR1, CSNK2A2, TRH, CTNNB1, CBS, GPX4, HSPA9, STAT3, AKR1C3, MTOR, VDAC2, BAG6, HSPA2, RAD23A, RAD23B, PTEN, TMSB4X, GNAI1, |
| nucleus-vacuole junction | cellular component | PIK3R4 |
| NuRD complex | cellular component | MTA2, MTA3, RBBP7, HDAC2, GATAD2A, CHD5, CSNK2A1, RBBP4, CHD4, MBD3, GATAD2B, ZBTB7A, CHD3 |
| NURF complex | cellular component | SMARCA5, RBBP4, SMARCA1, BPTF, HMGXB4 |
| oligosaccharyltransferase complex | cellular component | RPN2, STT3B, RPN1, STT3A, DDOST, OST4, MAGT1, OSTC, KRTCAP2, DAD1, TREX1 |
| oligosaccharyltransferase I complex | cellular component | STT3B, TMEM258 |
| oligosaccharyltransferase III complex | cellular component | STT3A |
| omegasome | cellular component | ZFYVE1, TRIM5 |
| oncostatin-M receptor complex | cellular component | IL6ST, OSMR |
| organelle inner membrane | cellular component | NEU4 |
| organelle membrane | cellular component | CYP1A1, PTGS1, SRD5A2, PTGS2, CYP1A2, CYP2B6, SRD5A1, MTOR, CYP21A2, CYP1B1, CYP26B1, CYB5A, SEC11A, PNPLA8, POMP, UGT2B7, CYP2J2, SEC11C, MAP1LC3A, UGT2B10, CYP4A11, CYP4F3, MGST3, TFPI, SPCS3, MGST2, SPCS1, SEC16A, SPCS2, CYP2R1, DNAJC1, DHRS9, FBXO2, UGT2B11, ACSL3, ACSL1, ALDH3A2, LRRC59, PGRMC1, CYP2A7, NAT8L, UGT2B28, CYP2C8, FLRT2, AADAC, CYP4F8, CYP26A1, CYP4B1, HSD17B6, CYP2A6, FMO3, CYP2C19, SQLE, CYP4F22, SLC39A8, CYP8B1, ATP1A3, SLC2A13, ATP1A2, UGT2B15, FA2H, ACSL4, CYP3A5, CYP2C18, VAC14, MAP1LC3B, UGT2B4, ATP2A3, CYP4F12, ATP1B1, CYP51A1, UGT2B17, TM7SF2, RDH10, ATP1A1, FMO4, TAPBPL, CYP2E1, CYP4F2, CYP4Z1, CYP4X1, CYP46A1, CYP2D6, CYP2S1, CYP2W1, FAAH, FMO1, RPE65, CYP4F11, EPHX1, CYP2C9, MAP1LC3C, CYP3A43 |
| organelle membrane contact site | cellular component | RMDN3, OSBPL1A, STARD3NL, ESYT2, GRAMD2A, GRAMD1A, STARD3, ESYT3, MOSPD2 |
| origin recognition complex | cellular component | ORC5, ORC1, ORC3, ORC2, ORC4 |
| outer acrosomal membrane | cellular component | TRIP11, EQTN |
| outer dense fiber | cellular component | ODF2, TXNDC2, ODF3, DDX6 |
| outer dense plaque of desmosome | cellular component | VCL |
| outer dynein arm | cellular component | NME8, DNAH5, DNAI1, CFAP70, DNAH17, DNAL1, DNAI2, DNAH8, CCDC114 |
| outer membrane | cellular component | SAMM50, ANKH, SLC24A1 |
| outer mitochondrial membrane protein complex | cellular component | MFN1 |
| oxidoreductase complex | cellular component | CBR4 |
| oxoglutarate dehydrogenase complex | cellular component | OGDH, OGDHL, KAT2A, DHTKD1, DLST |
| P granule | cellular component | PIWIL2, PIWIL1, DDX4, PIWIL4, TDRD9, MAEL, MOV10L1, DDX3X, HENMT1, EXD1, HELZ, SNRPG, CARHSP1, MOV10, DDX3Y, TDRD1 |
| P-body | cellular component | NANOS2, TOP1, NANOS3, PSMC2, PAN3, LSM1, PSMA2, LSM3, PUM1, CNOT1, ZC3H12A, AGO4, CNOT8, GARRE1, POLR2G, LSM14A, C9orf72, APOBEC3F, DCP2, HAX1, PNRC2, EIF4ENIF1, UPF1, AJUBA, AGO3, POLR2D, PSMC3, PSMA6, CAPRIN1, PAN2, EDC4, DCP1B, PATL1, RC3H2, SQSTM1, EIF4E, DDX6, CNOT9, CPEB1, SAMD4A, SHFL, RC3H1, XRN1, BTBD1, PSMA4, EDC3, APOBEC3G, AGO2, CARHSP1, NBDY, WTIP, CNOT2, TNRC6B, ZFP36, APOBEC3A, LSM6, ZFP36L1, TRIM71, TNRC6A, TNRC6C, YTHDF2, MOV10, DCP1A, APOBEC3C, MEX3B, AGO1, LIMD1, TRIM21, LSM2, CNOT3, DCPS, DIS3L2, BTBD2, ZC3H12D, SYNE1, SAMD4B, RBPMS, APOBEC3B, MEX3A, LSM4, TRIM5, LIN28A |
| palmitoyltransferase complex | cellular component | GOLGA7 |
| PAM complex, Tim23 associated import motor | cellular component | GRPEL1, DNAJC15, DNAJC19, GRPEL2, PAM16 |
| PAN complex | cellular component | PAN3, PAN2 |
| parallel fiber | cellular component | DAB2IP |
| parallel fiber to Purkinje cell synapse | cellular component | CTNNA2, SPTBN2, UNC13C, CADPS2, P2RX6, GRID2, GRIA3, KCNJ9, SLC6A9, CADM3, CNTN6 |
| paranodal junction | cellular component | AKR1B1, JAM3, SIRT2, CNTNAP2, NFASC, KCNA2, CNTNAP1 |
| paranode region of axon | cellular component | GJC2, EPB41L3, SIRT2, SCN2A, NFASC, KIF13B, MAG, KCNA1, CNTNAP1, SPTBN4, NCMAP |
| paraspeckles | cellular component | NUDT21, HNRNPM, PSPC1, SFPQ, NONO, CPSF6 |
| Parkin-FBXW7-Cul1 ubiquitin ligase complex | cellular component | FBXW7, PRKN, CUL1 |
| PAS complex | cellular component | VAC14 |
| PCAF complex | cellular component | TAF12, TADA2A, TAF10, KAT2B, TAF9 |
| PcG protein complex | cellular component | CSNK2A2, CSNK2B, CBX2, PCGF3, SKP1, PHC1, PCGF5, PCGF2, PCGF1, RYBP, CBX8, CBX6, PHC2, YY1, BMI1, CSNK2A1, SCML2, PHC3, CBX7, YY2, RING1, CBX4, RNF2, UBAP2L |
| PCNA complex | cellular component | PCNA |
| PCNA-p21 complex | cellular component | PCNA, CDKN1A |
| PCSK9-AnxA2 complex | cellular component | ANXA2, PCSK9 |
| PCSK9-LDLR complex | cellular component | LDLR, PCSK9 |
| PeBoW complex | cellular component | WDR12, PES1 |
| pericellular basket | cellular component | AMIGO1 |
| pericentric heterochromatin | cellular component | DNMT1, LRWD1, CBX1, ATRX, BAZ1B, KDM4C, KDM4D, MACROH2A1, CENPC, KMT5C, CBX5, HELLS, INCENP |
| pericentriolar material | cellular component | PCM1, DYRK3, NEDD1, NEK1, NIN, TCP1, TNKS, CDK5RAP2, CEP85, BBS9, HOOK3, BBS4, TUBE1, TNKS2, TUBG1, WDR60, LCK, TUBG2, CEP192, RABL2B |
| perichromatin fibrils | cellular component | TRIM24, NUFIP1, CPSF6 |
| periciliary membrane compartment | cellular component | KIF17, KIFAP3, USH2A, ADGRV1, WHRN, RP2 |
| perikaryon | cellular component | ESR1, FMR1, ESR2, BGLAP, MAPK1, GNRH1, NSMF, AIF1, ANXA5, TOP1, SHTN1, PAM, FUS, KCNAB1, GJC2, ASTN2, SLC2A3, G3BP1, NDN, OLFM1, RCVRN, DHX36, C9orf72, RTN4R, CTSV, CRYAB, RACK1, NEURL1, TTLL7, CPLX1, ASS1, ENO2, CACNA1C, SYNPO, NEUROG1, KCND2, ERCC8, DRP2, ENDOG, CRH, HPCA, SIRT2, GLRA3, PDE9A, DDN, CRHBP, MAP2K4, SCN1B, KLHL24, DBNL, GRIP1, GLUL, UCN, SLC8A3, CHRNA10, NCDN, CNTNAP2, PCSK2, PRPH, KIF5A, KCNB1, CDK5R1, RUFY3, SYAP1, ZPR1, ELAVL4, CTNND2, GRIK3, GRIK5, EFNA2, ATP7A, SMN1, WDFY3, AZIN2, SORCS2, PI4K2A, NPFF, BRD1, EPHA4, TMEM100, PPP5C, MCRS1, ROGDI, HDAC6, GLRA1, KNDC1, SERPINI1, KCNK1, ASTN1, CPNE6, TH, FZD5, SLC5A7, CCK, KCNA2, CDK5, PTPRS, GIGYF2, CPNE5, PDE10A, NGFR, RTN4RL2, KCNC2, NGB, GOT2, HTR5A, DMWD, TMEM266, RBFOX3, PDPK1, DRD2, NTSR1, KCNA1, AMIGO1, TRPM2, RGS8, CRMP1, SLC8A2, MYO1D, MAPK10, GRIK2, KCNC3, DLG2, RTN4RL1, TIAM2, MAP1B, LRRK2, CPLX2, SLC4A10, KCNE3, PENK, GAP43, ITGA8 |
| perineuronal net | cellular component | PTPRZ1 |
| perinuclear endoplasmic reticulum | cellular component | TRIM13, DBI, CAPN2, CYBB, CYBA, CREB3L2, GDPD5, BCAP31, OSBPL6, OSBPL7, SYT6, OSBPL3 |
| perinuclear endoplasmic reticulum membrane | cellular component | PIK3R1, DGAT2, MOGAT2, MOGAT3 |
| perinuclear region of cytoplasm | cellular component | GNAS, EGFR, ESR1, INHBA, TNFRSF1B, BDNF, FAS, INSL3, FKBP4, FMR1, BAX, ESR2, NDRG2, ERBB2, HSP90AA1, HMOX1, CDC25C, STAT1, FASLG, GSK3B, CIB1, TLR4, TF, GAPDH, APP, ITGB1, CLU, SRD5A1, CTNNB1, HFE, AKAP4, BRSK2, IGF2R, SRC, NOS2, PTGDS, NANOS2, LMTK2, PUM2, DDX4, HSPA1A, HSPA1B, CDH1, EZR, APEX1, PPARG, RAP1A, TWF1, CDC20, PLCZ1, 41153, NANOS1, PICK1, DNM1L, ALDH1A2, ANXA2, NF2, RANGAP1, AIF1, MYRIP, MAEL, ADCY10, GC, ANXA6, ANXA4, CSF1, PLA2G2A, GLB1, NANOS3, CX3CL1, KIAA0101, MALT1, SHTN1, SYNJ1, PSTPIP1, USO1, HSPA8, AKR1B1, ATP2A2, PAM, MCM3, CCN2, KIF5B, FUS, AQP2, SEPTIN2, CDKN3, COPS5, OPTN, CORO1B, GTPBP4, ALG2, UPF2, SEPTIN9, RTRAF, LPXN, COBL, UBR5, YBX3, PPIB, RAB11A, MLC1, SEC23B, SRCAP, CRBN, COPS8, TPPP3, ARFGEF1, MAP3K4, FZD9, RAB29, CDK7, FXR1, EIF4A2, FAT1, PTPRR, MEX3D, VPS52, TRAPPC12, FBXL5, MTMR6, SLC17A3, RAD51C, SEC31A, BCL10, ANP32A, PLAAT3, GALNT2, MOB2, COPS6, RASGRP3, NELL1, FBXW7, EPN3, SPINK5, FLRT1, STX8, MAPK8IP1, PIKFYVE, RAPGEF2, SEC16A, STX10, PRKRA, EIF3G, TRIM37, TGFA, CTSB |
| perinucleolar chromocenter | cellular component | PIWIL2, TINF2 |
| perinucleolar compartment | cellular component | EPPK1, SORL1 |
| peripheral region of growth cone | cellular component | CYFIP1 |
| perisynaptic extracellular matrix | cellular component | ACAN, TNC |
| perivitelline space | cellular component | OVGP1 |
| peroxisomal importomer complex | cellular component | PEX13, PEX12, PEX14 |
| peroxisomal matrix | cellular component | HSD17B4, CAT, IDH1, DAO, PEX7, MLYCD, SCP2, ECH1, HACL1, GRHPR, AMACR, AGPS, LONP2, GNPAT, PHYH, ACAA1, IDE, BAAT, PEX5, ECI2, ACOX3, NUDT12, CRAT, PAOX, PRDX5, FAR1, HAO2, AGXT, HMGCL, ACOT2, DDO, PIPOX, FAR2, POMC, ACOX2, ACOX1, ACOT4, ACOXL, HAO1 |
| peroxisomal membrane | cellular component | HSD17B4, MGST1, CAT, PEX10, DAO, PEX7, PEX2, PEX19, PNPLA8, CNOT1, TTC1, PXMP4, PEX11B, PLAAT3, TMEM135, FNDC5, AGPS, GNPAT, ACSL3, ACSL1, ALDH3A2, PEX26, RAB8B, HMGCR, PEX5, ARF1, PEX13, ABCD2, PEX12, PEX5L, MAP2K2, PEX3, SLC25A17, FIS1, ACSL4, PEX14, ACBD5, FAR1, PEX11G, PEX1, SLC27A2, PEX11A, PEX16, MPV17L, IMPDH2, TMEM35A, FAR2, PXMP2, ABCD1, DECR2, SYT7, MPV17, ACOX1, MAVS, ATAD1, PECR |
| peroxisome | cellular component | SOD1, HSD17B4, VIM, GSTK1, CAT, NOS2, XDH, IDH1, EPHX2, DNM1L, PEX10, DAO, PEX7, MLYCD, PEX2, PEX19, IDI1, PNPLA8, SCP2, ECH1, LACC1, HACL1, ACAD11, MFF, PXMP4, PEX11B, PLAAT3, TMEM135, FNDC5, AMACR, AGPS, TRIM37, PMVK, LONP2, GNPAT, ACSL3, ACSL1, ALDH3A2, PHYH, ACAA1, IDE, BAAT, PEX26, PEX5, PIK3C3, PEX13, MYO5A, ECI2, ABCD2, ACOX3, TKT, ZADH2, MTARC2, PEX12, CCDC33, NUDT17, HSDL2, NUDT12, CRAT, RIDA, PEX3, MIEF2, SLC25A17, IDH2, PAOX, MIEF1, FIS1, VWA8, AOC1, ISOC1, ACSL4, PEX14, PRDX5, SZT2, ACBD5, FAR1, PEX11G, PEX1, HAO2, SLC27A2, PEX11A, AGXT, STING1, PEX16, HMGCL, CD33, MPV17L, DDO, PIPOX, AKAP11, MARF1, GBF1, MUL1, DEPP1, MVD, TMEM35A, FAR2, PXMP2, POMC, ABCD1, MVK, DECR2, SYT7, ACOX2, URAD, MPV17, ACOX1, SERHL2, MAVS, ACOT4, ATAD1, ACOXL, HAO1, ABCD4, PECR |
| PET complex | cellular component | PIWIL2, EXD1, TDRD12 |
| phagocytic cup | cellular component | TNF, AIF1, RAB11FIP2, MEGF10, RACK1, ANXA1, RAB31, SNX5, CDC42SE2, TICAM2, IRGM, BIN2, TRIP10, LCP1, ADGRB1, ARHGAP25, CORO1A, ARHGAP12, ABCA7, PIP5K1C, PEAR1, MCOLN1, SH3BP1, MYO1G |
| phagocytic vesicle | cellular component | ITGAV, SNX3, KIF5B, RAB9A, STXBP4, STX12, RAB11A, RAB38, RAB11FIP5, STX8, CYBB, ITGB5, ZDHHC5, FLNB, VPS26B, PLD4, RAB5A, RAB31, RAB32, RAB8B, RAB20, PIK3C3, NOD2, RAB22A, KIF16B, CDC42EP2, ANXA11, RAB14, RAB23, SRGAP2, RAB7A, RAB39A, CDC42EP4, VAMP3, RAB11B, CLCN3, EVL, VAMP7, ACTG1, UVRAG, STXBP3, LAMP1, APPL2, TLR9, PLA2G5, TLR7, WAS, STX4, MYO1C, CORO1A, RAB8A, TCIRG1, RAB34, APPL1, STXBP2, UNC93B1, AMBRA1, FMNL1, CD36, ZYX, RAB9B |
| phagocytic vesicle lumen | cellular component | LTF, GNLY, MPO |
| phagocytic vesicle membrane | cellular component | HLA-B, HLA-A, HLA-E, ATP6V0A2, TLR2, B2M, HLA-G, HLA-C, RAB9A, SEC22B, RAB38, SNAP23, CYBB, ANXA3, OCRL, VAMP8, TAP1, ATG12, RAB5A, RAB31, RAB32, RAB8B, HVCN1, RAB20, ATP6V0E1, TAP2, PIK3C3, RAB22A, LAMP2, CYBA, DMBT1, TLR1, ATG5, RAPGEF1, RAB23, RAB7A, RAB39A, VAMP3, RAB11B, TAPBP, RAB11FIP1, ATP6V0E2, RAC2, VAMP7, ATP7A, PIK3R4, IRGM, INPP5B, SLC11A1, ATP6V0D1, APPL2, ATP6V0B, ATP6V0A4, RILP, STX4, CORO1A, RAB8A, TCIRG1, PIP4P1, RAB34, ATP6V0C, MCOLN1, SYT7, CALR, TLR6, HLA-F, PIP4P2, ATP6V0A1, RAB9B |
| phagolysosome | cellular component | NCF1, PLA2G5, NCF4, ADAM8 |
| phagolysosome membrane | cellular component | LAMP1 |
| phagophore assembly site | cellular component | NBR1, STX12, RB1CC1, PIK3C3, ZFYVE1, ULK2, ILRUN, ULK1, SQSTM1, ULK3, WDR45, ATG2B, WIPI2, BECN1, WDR45B, ATG9A, WIPI1, TRAPPC8, ATG101, ATG2A, ATG13, ATG9B, VMP1 |
| phagophore assembly site membrane | cellular component | RB1CC1, ATG12, ULK2, ATG5, ULK1, WDR45, RAB7A, ATG2B, WIPI2, WDR45B, WIPI1, STBD1, ATG2A, RAB1B, ATG16L1 |
| phenylalanine-tRNA ligase complex | cellular component | FARSB, FARSA |
| phosphatidylinositol 3-kinase complex | cellular component | MTOR, PIK3CA, CISH, PIK3C2A, SOCS2, PIK3R1, SOCS5, SOCS4, SOCS1, SLA2, PIK3R3, SOCS7, PIK3CG, PIK3C2B, SOCS6, PIK3CD, PIK3R2, PIK3R6, PIK3R5, SOCS3 |
| phosphatidylinositol 3-kinase complex, class IA | cellular component | PIK3CA, PIK3R1 |
| phosphatidylinositol 3-kinase complex, class IB | cellular component | PIK3CG, PIK3R6, PIK3R5 |
| phosphatidylinositol 3-kinase complex, class III | cellular component | PIK3C3, BECN1, NRBF2, PIK3R4 |
| phosphatidylinositol 3-kinase complex, class III, type I | cellular component | PIK3C3, BECN1, PIK3R4 |
| phosphatidylinositol 3-kinase complex, class III, type II | cellular component | PIK3C3, BECN1, PIK3R4 |
| phosphopyruvate hydratase complex | cellular component | ENO1, ENO2, ENO3 |
| phosphorylase kinase complex | cellular component | PHKB, PHKG2, PHKA2, PHKG1 |
| photoreceptor cell cilium | cellular component | IFT52, RP1, ATP1A4, SDCCAG8 |
| photoreceptor connecting cilium | cellular component | NPHP1, NPHP4, SEPTIN2, USH1G, WDR19, IFT57, KIF17, CETN2, RPGRIP1, IFT52, SPTBN5, KIFAP3, CETN1, KIAA1549, ARL3, USH2A, RP1, TBCC, BBS4, USH1C, FAM161A, CEP290, CFAP410, IFT122, PCDHB15, LCA5, MYO7A, WHRN, RP1L1, PDZD7, IQCB1, TOPORS, RPGRIP1L, TMEM237, SPATA7 |
| photoreceptor disc membrane | cellular component | SPTBN5, GRK4, GNB1, ABCA4, PDE6A, GUCY2F, GUCA1A, GNGT1, PDE6G, GUCY2D, GRK7, PDE6B, RHO, GRK1, OPN4, GUCA1C |
| photoreceptor distal connecting cilium | cellular component | RPGRIP1, SPATA7 |
| photoreceptor inner segment | cellular component | MAK, INHA, USH1G, RCVRN, PPEF2, PHLPP2, TULP1, GNB1, GUK1, PCARE, ENO2, CCDC66, USH2A, GNAT2, RP1, DNM3, BBS4, USH1C, SHANK2, ATP1A3, SNAP25, GNGT1, USP45, REEP6, KIAA0586, CIB2, SAG, FAM161A, DRAM2, ADGRV1, CRB1, C8orf37, CEP250, AIPL1, ATP1B2, RD3, RDH12, DNM1, MYO7A, WHRN, RHO, CROCC, PDZD7, PRPH2 |
| photoreceptor inner segment membrane | cellular component | ATP1A3, ATP1A1, RDH12, RHO |
| photoreceptor outer segment | cellular component | PTGS1, MAK, INHA, MYRIP, WDR19, RCVRN, RAB27A, PPEF2, RPGR, OCRL, LYAR, TULP1, GNB1, ABCA4, OPN5, PCARE, CCDC66, GNAT2, RP1, MYO5A, BBS4, USH1C, SHANK2, GUCA1A, GNGT1, GNA11, ATP8A2, CIB2, SAG, GNAQ, CNGB3, CFAP410, ROM1, CEP250, GUCY2D, GUCA2B, RD3, CNGB1, PDE6B, MYO7A, RHO, PRCD, MERTK, GRK1, RP1L1, IQCB1, EYS, MAP1B, RGS9BP, PCDH15, OPN3, PRPH2, NXNL1, SPATA7 |
| photoreceptor outer segment membrane | cellular component | DHRS3, PHLPP2, GNB1, GNAT2, CDHR1, NAPEPLD, ROM1, PDE6G, GUCY2D, RHO, PRCD |
| photoreceptor ribbon synapse | cellular component | HSPA8, SH3GL2, CTBP2, DNM1, PACSIN1, CACNB2, CPLX3 |
| pi-body | cellular component | PIWIL2, DDX4, MOV10L1, TDRKH, TDRD1 |
| Piccolo NuA4 histone acetyltransferase complex | cellular component | EPC2, ING3, KAT5, EPC1 |
| pICln-Sm protein complex | cellular component | CLNS1A, SNRPE, SNRPD1, SNRPD2, SNRPF |
| pinceau fiber | cellular component | KCNAB2 |
| piP-body | cellular component | DDX4, PIWIL4, TDRD9, MAEL, TDRKH |
| plasma membrane | cellular component | SOD1, EGFR, F10, SERPINC1, EGF, TGFB1, TNF, HLA-DRB1, APOE, ESR1, HLA-DPB1, ICAM1, MMP2, IL6R, TGFB3, ACE, CD44, IL1RN, TNFRSF1A, TNFRSF1B, KITLG, LHCGR, ANOS1, FSHR, FAS, NOS3, BRCA1, IL6ST, LIG4, GNAS, CYP24A1, NOSTRIN, CATSPER1, RXFP2, ESR2, CATSPER2, IGF2, HLA-B, HLA-DQB1, APOB, HLA-A, ERBB2, SERPINE1, HSP90AA1, ABCB1, CFTR, HLA-E, FLT1, FGFR2, FGFR3, AXL, AKT1, KDR, CASP3, KIR2DL2, KIR2DS2, FASLG, GSK3B, UBE2B, S100A12, MDM2, ADCY2, KANK1, NFE2L2, UBR2, MBD3L1, CIB1, ATP6V0A2, TLR4, TLR2, SEMA7A, C3, HLA-DRA, KRT1, GAPDH, HSPB1, APP, ITGB1, ENO1, ITGA5, VIM, GSTP1, GNAO1, FGFR1, F5, F3, PRLR, TRH, EDNRA, GNRHR, ABCC1, CTNNB1, STAT3, LEPR, IFNAR2, PTEN, B2M, GNAI1, CSNK2B, TGFBR3, PLAUR, CLCA4, PON2, HFE, COA6, NSMF, PARK7, IL1RAPL1, IL2RA, HLA-DQA1, CAT, IGF1, INSR, ITGAV, YES1, IGF1R, KIT, HSPA5, IGF2R, CD79A, SRC, ITGA4, CD99, CD46, MUC1, HLA-G, FPR1, ITGA6, CD52, CD68, PIK3CA, DPP6, CACNA2D1, GFRA1, SLC7A5, NRG1, C1QBP, BMPR2, PDCD1, GPRC6A, IZUMO1, PROKR2, KISS1R, SLC22A18, MUC13, KCNK9, CD320, SLC6A |
| plasma membrane bounded cell projection | cellular component | ATP2A2 |
| plasma membrane bounded cell projection cytoplasm | cellular component | AKR1B1 |
| plasma membrane proton-transporting V-type ATPase complex | cellular component | ATP6V0D1, ATP6AP1 |
| plasma membrane raft | cellular component | EZR, PRKAR2A, KCND2, ITGAM, HAS2, CHRNA7, SKAP1, LYPD4, FLOT1, CHRNA3, ADCY8, ADD3, ADD2, MS4A1, LCP2, SELPLG, ITGB2, MAL, ADD1, DAG1, CHRNB2, PRTN3, LRP4, MYO1D, STIM1, TEX101 |
| platelet alpha granule | cellular component | VWF, F5, SERPINA5, TREML1, VPS33B, FGG, THBS1, FGB, VAMP7, STXBP3, FGA, PPBP, THBS2 |
| platelet alpha granule lumen | cellular component | TIMP1, EGF, TGFB1, TGFB3, VEGFA, IGF2, VWF, SERPINE1, GAS6, SERPINA1, ALB, APP, CLU, F5, TMSB4X, A2M, IGF1, HGF, FN1, SERPINA3, SCCPDH, CFD, PDGFB, VTI1B, ORM1, FGG, OLA1, MAGED2, QSOX1, PROS1, THBS1, SERPINF2, PF4, ACTN2, FGB, ALDOA, PDGFA, NHLRC2, SRGN, TGFB2, ACTN1, VEGFC, ORM2, F8, MMRN1, PLG, FGA, PPBP, VEGFB, TOR4A, HRG, SERPING1, FERMT3, ISLR, LEFTY2, ACTN4, AHSG, GTPBP2 |
| platelet alpha granule membrane | cellular component | CD9, LHFPL2, ITGA2B, SNCA, SYTL4, APLP2, SELP, ITGB3, CD109, PECAM1, PHACTR2, CD36, TMX3 |
| platelet dense granule | cellular component | HPS4 |
| platelet dense granule lumen | cellular component | LGALS3BP, ECM1, CTSW, TIMP3, SELENOP, SERPINA4, CDC37L1, FAM3C, CLEC3B, RARRES2, ITIH4, ITIH3, SPP2, APOH |
| platelet dense granule membrane | cellular component | RAB27B, LAMP2, CD63, SELP, ITPR1, ABCC4 |
| platelet dense tubular network | cellular component | SERPINA5, F2R, ITPR1 |
| platelet dense tubular network membrane | cellular component | ATP2A2, IRAG1, ITPR3, ITPR1, ATP2A3, ITPR2, DMTN, ATP2A1 |
| plus-end kinesin complex | cellular component | KIF3B, KIF15, BORCS5 |
| PML body | cellular component | TP53, TERT, MTOR, PTEN, PARK7, RB1, ATR, CDK9, SUMO1, TCF7L2, NBN, SKIL, EIF3E, SENP2, ZMYM2, PIAS1, SUMO3, MAX, NSMCE2, RPA2, SP140, THAP1, PIAS2, MAGEA2, ATRX, SUMO2, TP53INP1, ISG20, MORC3, SMC5, CHFR, ANKRD2, RPA1, HIPK1, EIF4ENIF1, PPARGC1A, LRCH4, HIRA, SP3, TDG, RFWD3, TOPBP1, MKNK2, RNF6, SKI, UBE2I, IKBKE, MLIP, RDM1, TRIM8, PATL1, MRE11, SQSTM1, SATB1, HIPK3, SP100, HIPK2, TENM2, ZNF451, BASP1, TDP2, NR2C1, MAPK7, RNF111, USP7, KLHL20, PML, CALCOCO2, WDFY3, BLM, HMBOX1, ELF4, SRSF2, NFE2, CIITA, CASP8AP2, ARNTL, TRIM16, SPN, CBX5, ZBTB16, KAT6A, RGS14, PIAS4, UBN1, AKAP8L, SPTBN4, TOPORS, N4BP1 |
| podosome | cellular component | LPXN, PALLD, TJP1, SCIN, SVIL, VCAM1, RHOU, WDR1, ARHGEF5, CTTN, DBNL, ARHGEF2, VCL, KIF9, BIN2, LCP1, PTPN12, FERMT3, HNRNPK, ADAM8, SH3PXD2B, FSCN1, SH3PXD2A, SH3GL1, ASAP1 |
| podosome core | cellular component | ACTR2 |
| polar microtubule | cellular component | KLHL22, TUBGCP3, TUBG1, KLHL21 |
| pole plasm | cellular component | WDR77 |
| polkadots | cellular component | BCL10 |
| polycystin complex | cellular component | PKD1, PKD2 |
| polysomal ribosome | cellular component | FMR1, NR0B1, EIF3H, RPL31, RPL24, RPL6, BTF3, RPL7A, RPL32, RPS21, RPL11, RPL19, RPS23, RPL41, RPL30, RPL38, RPL39, RPL8, EEF2, RPL18A, RPS29, RPL10A, RPS28, RPL36, NUFIP2, PNPT1, RPL18, LARP1, RPL36A, ABCF1, LARP4B |
| polysome | cellular component | FMR1, PIWIL2, DAZL, PIWIL1, FUS, RPS4X, RPL10L, UPF2, PSMA1, MYH10, RWDD1, DRG1, FXR1, HSPA14, VBP1, RPS3, HDLBP, NAA35, RPS4Y1, GCN1, EEF2, PSMA6, UNK, NAA30, EIF4B, FXR2, EIF2S1, LARP6, AGO2, LARP1, MCRS1, MSI1, AGO1, DIS3L2, IMPACT, CALR, ATXN2, NAA38, EIF4H, LIN28A |
| pore complex | cellular component | BCL2, BAX, BAK1, VDAC2, VDAC1, TOMM40, AFDN |
| post-mRNA release spliceosomal complex | cellular component | XAB2, HNRNPM, CWF19L1, CWF19L2, SYF2, CCDC130, CCDC12, ISY1, MYEF2, CRNKL1 |
| post-spliceosomal complex | cellular component | ISY1 |
| postsynapse | cellular component | FMR1, AKT1, GHRL, CX3CL1, C1QB, PRNP, ERBIN, PSMA7, JAK2, RPLP0, BAIAP2, FZD9, FXR1, RNF19A, WASF3, GABRA2, PTN, PURA, GIPC1, EPHB2, PSMC5, STX3, EIF4EBP2, AP3D1, CPLX1, PFN2, PPP1R1B, EPS15, RPL8, SPTBN1, GHSR, MYO5A, CALB1, GABRG2, HPCA, MEF2C, METTL5, GABRA5, SCRIB, CPEB4, PSD2, C1QC, CHRNA7, NCDN, EIF4E, GABRA4, SNAP25, GABRG1, ADGRB3, GRIA2, MECP2, RAC1, AP2B1, ABL1, NCS1, CYFIP1, CPEB3, NPFF, DNAJB1, ACTR2, HOMER1, WASF1, PDLIM5, NAPA, DLG4, P2RX7, SEPTIN11, OPHN1, PRKAR2B, HCRT, CDK5, KIF1A, STX4, C1QA, GABRA1, RAB3GAP1, APC2, GABRA3, CPT1C, P2RX5, DYNLL2, SLC29A1, CYP46A1, GRIA1, NPAS4, NRGN, DGKQ, CLSTN3, SRCIN1, P2RX2, PTK2B, GABRG3, DRD4, INA, LRRK2, CPLX2, SLC4A10, ZNF804A, ATAD1, VPS35, SLC17A7, AGER, SLC6A17 |
| postsynaptic actin cytoskeleton | cellular component | CTTNBP2, PPP1R9A, KPTN, ITSN1 |
| postsynaptic cytosol | cellular component | HSPA8, BAIAP2, PIN1, CALB1, PLCB3, NEDD4, EIF4EBP1, EIF4E, NCS1, HOMER1, HTT, DAG1, PRKCG, EIF4A3, FBXO45 |
| postsynaptic density | cellular component | FMR1, NSMF, SRC, NCOA2, SOS1, PICK1, GOPC, PJA2, PRNP, RPS14, RPL6, BCL11A, RPLP0, GRM3, MIB1, BAIAP2, EEF2K, RPL7, FXR1, RPS18, RPS13, ALS2, RTN4, NPTN, ARHGAP32, ADGRL1, GRIN1, BAALC, PPP1R9B, CRYAB, NEFH, RPS19, NSF, RPS25, RPL30, RPL38, DLG5, PSD3, CACNG2, DVL1, MPDZ, NEURL1, RPS3, FABP5, EIF3A, CNN3, GSG1L, SEMA4C, EPB41L3, DLGAP1, BCR, MAP4, RPS27, TSC1, ARHGEF9, CTNNA2, RPL8, SPTBN1, CACNA1C, MPP2, CTTN, SYNPO, LRRC1, DISC1, KCND2, NCK2, ARF1, DRP2, HOMER2, DNM3, DGKI, NTRK2, ARFGAP1, PHB2, SYN1, MX1, HNRNPH2, SCRIB, CPEB4, IQSEC1, DTNBP1, PKP4, DBNL, SHANK2, GRIP1, SLC8A3, RPL18A, DGKZ, INPP4A, BSN, SORCS3, STRN, SRGAP2, RPL12, RPL10A, CNKSR2, CPEB1, MAP2, CHRNA3, GRIA2, RPL14, FXR2, PDE4B, EPS8, DLG1, BNIP3, TIAM1, CDK5R1, RHEB, TMEM108, SHARPIN, GPHN, CRIPT, IQSEC3, ADCY8, ADD3, CTNND2, SLC8A1, ADD2, NCS1, GRIK5, SNAP47, ABI1, ARHGEF2, LYN, KPNA1, GNG3, PRKCZ, ABHD17B, CPEB3, SORCS2, ZDHHC2, DCLK1, DNAJB1, EPHA4, ACTR2, SPOCK1, GRIN2B, ITPR1, HOMER1, PDLIM5, EGLN1, CABP1, DNAJC6, HCLS1, DLG4, NETO2, |
| postsynaptic density membrane | cellular component | PRRT2, GRIN1, NLGN4X, LIN7C, CACNG2, SEMA4C, LIN7A, CACNA1C, CACNG3, ACTN2, NLGN4Y, GRIA2, DLG1, GRIN2C, GRIK3, GRIK5, ABHD17B, SORCS2, EPHA4, GRIN2B, DLG4, CACNG4, GRIN3A, GRID2, GRIA3, GRIK4, SIGMAR1, GRIN2A, SYNDIG1, GRIN3B, GRIA1, ATP2B2, LRFN1, GRID1, PRR7, ABHD17A, DAGLA, SHISA7, GRIN2D, RGS9, GRIK1, GRM5, GRIK2, DLG2, SYNJ2BP, NETO1, CACNG8, LIN7B, GRM1 |
| postsynaptic density, intracellular component | cellular component | BAIAP2, CTNND1, BCR, ABR, SH3GL3, CTNNA2, ACTN2, CDKL5, TNIK, ARHGEF2, PSD, DLG3, PRR7, SH3GL1 |
| postsynaptic early endosome | cellular component | RAB5A |
| postsynaptic endocytic zone | cellular component | GRIA2, CALY, RNF216 |
| postsynaptic endocytic zone cytoplasmic component | cellular component | CLTA, CLTB |
| postsynaptic endocytic zone membrane | cellular component | DNM3, MX1, MX2, DNM1 |
| postsynaptic endosome | cellular component | SH3GL3, CLSTN1, NSG1 |
| postsynaptic Golgi apparatus | cellular component | TM9SF2, MYO18A, GLG1, LRP1, TPPP |
| postsynaptic intermediate filament cytoskeleton | cellular component | NEFH, NEFL |
| postsynaptic membrane | cellular component | PTEN, NSMF, IL1RAPL1, COMT, F2R, PICK1, ANK1, LRRC4C, GOPC, GABRB1, PRRT2, CHRNA5, GRM3, ATP6AP2, ANK3, RAPSN, DMD, GABRA2, CHRNE, GRIN1, NLGN4X, HTR3B, HTR3A, LIN7C, UTRN, SEMA4C, LIN7A, CACNA1C, CTTN, LRRTM1, NLGN2, LRRC1, KCND2, PICALM, CHRNA2, CNIH3, ZC4H2, LRFN2, DNM3, GABRG2, GABRB3, GLRA3, DDN, CHRNB1, MX1, GABRA5, SCRIB, DTNBP1, DBNL, SHANK2, GRIP1, CHRM3, CHRNA7, CHRND, CHRNA10, STRN, SRGAP2, GABRB2, GABRA4, LRRTM4, GABRG1, NLGN4Y, CNKSR2, ITGB3, CHRNA3, GRIA2, ANK2, KCNB1, GRIN2C, LHFPL4, SYAP1, GPHN, TENM2, IQSEC3, SHC4, CADPS2, SLC8A1, GRIK3, GRIK5, KCTD12, OPRD1, ABHD17B, SORCS2, GABRP, EPHA4, GRIN2B, FAIM2, GABRD, HCLS1, KCNJ4, DLG4, GLRA1, P2RY1, SSPN, CHRNA6, GRIN3A, LRRC4, GABBR1, GRID2, MX2, EPHA7, DAGLB, LRFN3, RPH3A, CLSTN1, PCDH8, GABRR2, GRIA3, PDLIM4, DAG1, GRIK4, CNIH2, KCTD8, SIGMAR1, CHRNG, CHRM4, CHRM1, GABRA1, GRIN2A, KCNC2, TMUB1, SYNDIG1, LZTS1, GRIN3B, CHRM5, CHRNB2, GABRA3, NSG1, CHRNA4, DNM1, ACP4, GABRQ, GRID2IP, APBB1, LRRTM2, ARRB2, GRIA1, SYNE1, NRGN, LRFN1, GRID1, IGSF9B, |
| postsynaptic recycling endosome | cellular component | STX12, RAB11A, GRIPAP1, RAB4A, ZDHHC2, AKAP5 |
| postsynaptic specialization | cellular component | DLGAP4, GPHN |
| postsynaptic specialization membrane | cellular component | HSPA8, RAPSN, GPHN |
| postsynaptic specialization of symmetric synapse | cellular component | IQSEC3, SEPTIN11, IGSF9B |
| postsynaptic specialization, intracellular component | cellular component | SRGN, LYN |
| postsynaptic spectrin-associated cytoskeleton | cellular component | SPTBN2 |
| potassium channel complex | cellular component | KCNK4, KCNAB1, CCDC51, KCNA6, KCNK1, KCNA2, KCNIP2, KCNA1 |
| potassium ion-transporting ATPase complex | cellular component | ABCC9, KCNJ8, ABCC8 |
| PR-DUB complex | cellular component | ASXL2, ASXL1, BAP1, ASXL3 |
| PRC1 complex | cellular component | CBX2, PCGF3, SAMD13, PHC1, PCGF5, PCGF2, PCGF1, CBX8, PHC2, BMI1, PHC3, CBX7, RING1, CBX4, RNF2 |
| pre-snoRNP complex | cellular component | NOP58, ZNHIT3, NOP56, NUFIP1, ZNHIT6, TAF9 |
| precatalytic spliceosome | cellular component | RBMX2, LSM3, PHF5A, PRPF31, SNU13, SNRPE, SF3B2, PRPF38A, WBP4, SNRPD1, SNRPD2, SNRPG, SMU1, LSM8, LSM2, PRPF38B |
| prefoldin complex | cellular component | PFDN5, VBP1, PFDN4, PDRG1, PFDN1, PFDN6 |
| preribosome | cellular component | IMP3, IMP4, PIN4 |
| preribosome, large subunit precursor | cellular component | NSA2, RPF1, MRTO4, RRP15, WDR12, EBNA1BP2, NIP7, MDN1, ZNF622, WDR74, WDR37, EIF6, RRS1, ZNF593, PES1, RRP1B, FBXW9, FTSJ3, PPAN |
| preribosome, small subunit precursor | cellular component | RIOK1, NOB1, RIOK3, TSR1, UTP20, LTV1, RRP1B, RIOK2, FAM207A, FTSJ3 |
| prespliceosome | cellular component | XAB2 |
| presynapse | cellular component | FMR1, PARK7, SYNJ1, HSPA8, KCNJ10, PRRT2, GRM4, RAB2B, BAIAP2, SLC22A2, SGTA, FXR1, VPS18, SNAP23, NLGN4X, RTN4R, RAB6B, PTN, SNCA, KIAA1109, SH3GL2, LIN7C, DVL1, GNB5, GIPC1, AP3D1, CPLX1, PRKN, PFN2, PPP3CC, NRXN1, SH3GL3, LIN7A, SYNJ2, RAB8B, VAMP1, WNT3A, DNM3, SNAP29, METTL5, NRXN2, SYN1, MX1, SCRIB, CADPS, STX1B, SYT12, BSN, SPTBN2, NLGN4Y, FLOT1, CNR1, FXR2, SLC29A2, CDK5R1, AAK1, UNC13C, AP2B1, CADPS2, TNIK, UNC13B, PPFIBP2, ATP2B3, DNAJC5, STXBP3, PDLIM5, ITSN2, BLOC1S6, GAK, DNAJC6, SLC2A4, NAPA, DLG4, NAAA, P2RX7, ROGDI, RAB33B, OPHN1, YWHAG, ARF6, GRAP, GABBR1, PLD2, MME, MX2, SLC5A7, HRH3, SLC1A7, CDK5, KIF1A, SLC4A8, BACE1, SYNDIG1, CHAT, CABP4, SLC29A1, CYP46A1, APBB1, PIP5K1C, PLEKHG5, ATP2B2, KCNA1, SEPTIN8, UNC13A, BAIAP3, DGKQ, CACNA1B, STXBP2, SV2A, ATCAY, SH3GL1, SYT3, SRCIN1, SLC8A2, WNT7A, SLC22A1, SLC22A3, NF1, DOC2B, ARHGAP44, SYT10, STON2, TBC1D24, HAP1, CACNB2, CPLX2, SLC4A10, ZNF804A, FBXL20, VPS35, LIN7B, SEPTIN3, FBXO45, Grn, C1QBP, SLC6A17 |
| presynaptic active zone | cellular component | NCOA2, PPFIA1, RIMS2, PNISR, RIMS1, TPRG1L, PPFIA2, FZD3, DGKI, SYP, PHB2, SYN1, GAD1, GUCY1B1, BSN, FLOT1, UNC13C, ADCY8, NUFIP1, UNC13B, PPFIBP2, ERC2, PPFIA3, EGFLAM, RIMS3, UNC13A, PPFIA4, ADORA2A, SV2A, BRSK1, SLC32A1, GRM7, ARHGAP44, PPFIBP1, RIMS4, SLC17A7, C1QBP, GPER1 |
| presynaptic active zone cytoplasmic component | cellular component | RIMS2, RIMS1, CTNND1, CTNNA2, CTBP2, BSN, UNC13C, UNC13B, CTBP1, ERC2, PPFIA3, RIMS3, UNC13A, RIMS4 |
| presynaptic active zone membrane | cellular component | STX3, OTOF, STX1B, APBA1, STX4, STX11, CNTNAP1 |
| presynaptic cytoskeleton | cellular component | SEPTIN3 |
| presynaptic cytosol | cellular component | HSPA8, BAIAP2, SH3GL2, TRIM9, PPP3CC, CTBP2, STXBP5, CALB1, PRKCB, NCS1, HTT, PRKCG, LRRK2, FBXO45 |
| presynaptic endocytic zone | cellular component | ITSN1, PACSIN1 |
| presynaptic endocytic zone membrane | cellular component | CLTA, FCHO2, CLTB, DNM1 |
| presynaptic endosome | cellular component | AP3D1 |
| presynaptic intermediate filament cytoskeleton | cellular component | NEFL |
| presynaptic membrane | cellular component | PICK1, PRRT2, GRM3, ZNRF2, RIMS2, SNCAIP, SLC6A2, NPTN, ADGRL1, RIMS1, STX3, ZDHHC17, NRXN1, DENND1A, NLGN2, SYT1, PICALM, SNPH, SNAP91, SYP, SCRIB, OTOF, LRRC4B, STX1B, SNAP25, ERC1, EXOC3, CNR1, UNC13C, SYAP1, ADCY8, CADPS2, UNC13B, GRIK3, GRIK5, KCTD12, PI4K2A, GRM2, NECTIN1, GABBR1, CASK, ERC2, LRFN3, PCDH8, KCNA2, STX4, GRIK4, SLC4A8, KCTD8, STX11, KCNC1, GRIN2A, IL31RA, KCNC2, RIMS3, PDE2A, APBB1, KCNA1, UNC13A, SYT7, ADORA2A, SLC6A3, GRIK1, GRIK2, KCNC3, IGSF21, GAD2, CNTNAP4, RIMS4, FBXO45, GPER1 |
| primary dendrite | cellular component | MAP2 |
| procollagen-proline 4-dioxygenase complex | cellular component | P4HB, P4HA1 |
| prominosome | cellular component | PROM2 |
| pronucleus | cellular component | HSF1, EZH2, HNRNPL, EED, CENPF |
| protease inhibitor complex | cellular component | CARD16 |
| proteasome accessory complex | cellular component | PSMC2, PSMC6, PSMD6, PSMD1, PSMD14, PSMD8, PSMC5, PSMD4, PSMC3, PSMD12, PSMC4, PSMD2, PSMD5, PSMD3, PSMC1, PSMD13 |
| proteasome activator complex | cellular component | PSME1 |
| proteasome complex | cellular component | HSPB1, RAD23A, RAD23B, WFS1, PSMA3, PSMB1, PSMB5, PSMC2, UBE3A, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMC6, UBE3C, PSMB7, USP14, PSMD6, PSMD1, PSMD14, PSMD7, PSMB6, PSMD10, PSMD8, PSMC5, PSMB4, PSME1, PSMB8, PSMD4, PSMC3, PSMA6, ZFAND2B, UBR1, ZFAND2A, TXNL1, ADRM1, PSMD12, PSMB9, PSMC4, PSMA4, PSMD2, PSMD5, PSMF1, PSMB3, PSMD3, PSMC1, UCHL5, DNAJB2, PSMD13, PSMB10 |
| proteasome core complex | cellular component | PSMA3, PSMB1, PSMB5, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, PSMB6, PSMB4, PSMB8, PSMA6, PSMB9, PSMA4, PSMF1, PSMB3, PSMB10 |
| proteasome core complex, alpha-subunit complex | cellular component | PSMA3, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMA6, PSMA4 |
| proteasome core complex, beta-subunit complex | cellular component | PSMB1, PSMB5, PSMB2, PSMB7, PSMB6, PSMB4, PSMB8, PSMB9, PSMB3, PSMB10 |
| proteasome regulatory particle | cellular component | PSMD6, PSMD1, PSMD7, PSMD8, PSMC5, PSMD12, PSMD9, PSMD2, PSMD3, PSMC1, PSMD13 |
| proteasome regulatory particle, base subcomplex | cellular component | PSMC2, PSMC6, PSMD1, PSMD10, PSMC5, PSMD4, PSMC3, PSMC4, PSMD9, PSMD2, PSMD5, PSMC1 |
| proteasome regulatory particle, lid subcomplex | cellular component | PSMD14, PSMD8, ADRM1, PSMD12, PSMD3, PSMD13 |
| proteasome storage granule | cellular component | PSMD1, PSMD2 |
| protein C inhibitor-coagulation factor V complex | cellular component | SERPINA5 |
| protein C inhibitor-coagulation factor Xa complex | cellular component | SERPINA5 |
| protein C inhibitor-coagulation factor XI complex | cellular component | SERPINA5 |
| protein C inhibitor-KLK3 complex | cellular component | SERPINA5 |
| protein C inhibitor-plasma kallikrein complex | cellular component | SERPINA5 |
| protein C inhibitor-PLAT complex | cellular component | SERPINA5 |
| protein C inhibitor-PLAU complex | cellular component | SERPINA5 |
| protein C inhibitor-thrombin complex | cellular component | SERPINA5 |
| protein C inhibitor-TMPRSS11E complex | cellular component | SERPINA5 |
| protein C inhibitor-TMPRSS7 complex | cellular component | SERPINA5 |
| protein complex | cellular component | SOD1, ESR1, TP53, AR, PTGS2, BRCA1, SOX9, BRCA2, FKBP4, OGG1, HSP90AA1, CFTR, HNF1A, DNMT1, MAPK3, MAPK1, AKT1, GSK3B, HSF1, MDM2, CASP8, CDKN2A, MBD2, MTA2, ALB, KLK3, GNAO1, PARP1, CLU, CTNNB1, GNAI1, LTF, SEMG1, SERPINA5, ACR, POLG, EPPIN, HSPD1, YWHAQ, ACTB, PTPN11, CDC20, DNM1L, NTRK1, ANXA2, TOP2A, NF2, SIN3A, TP63, MT-CYB, MYC, ANXA6, VDAC1, HIST1H4A, GOPC, MALT1 |
| protein complex involved in cell adhesion | cellular component | JAM3, CTLA4, CD28, JAM2, CD80 |
| protein farnesyltransferase complex | cellular component | FNTA, FNTB |
| protein kinase 5 complex | cellular component | CDK5R1, CDK5R2, CDK5 |
| protein kinase CK2 complex | cellular component | CSNK2B, CSNK2A1 |
| protein kinase complex | cellular component | NEK10, MAP3K5 |
| protein N-acetylglucosaminyltransferase complex | cellular component | OGT |
| protein phosphatase 4 complex | cellular component | PPP4R1, PPP4R2, PPP4R3B, PPP4C |
| protein phosphatase type 1 complex | cellular component | PPP1R9B, NCK1, PPP1R3D, SHOC2, PPP1CB, PPP1R3C, PPP1R3B, PPP1R15A |
| protein phosphatase type 2A complex | cellular component | CYCS, PPP2R2B, PPP2R3A, PPP2R5A, PPP2CA, PPP2R2A, PPP2R1B, PPP2R5C, PPP2R2C, PPP2R5E, PPP2R5D, PPP2R2D, IER5, PPP2R1A, NKD1 |
| protein serine/threonine phosphatase complex | cellular component | PPP4R1, PPP2R1B, PPP4R4, PPP2R1A |
| protein-DNA complex | cellular component | ESR2, SP1, NFE2L2, CTNNB1, TCF7L2, NPM1, DDIT3, MAX, XRCC5, SUZ12, GTF2B, NUPR1, SOX12, SP3, XRCC6, HMGA2, RAD52, NFYC, EP300, TBX5, NFYA, PRKDC, NFYB, LEF1, FOS, NFE2, EYA1, JUP, MYOG, ZBTB17, ATF6B, KDM5A, HOXA11, POLR2H, JUND, NKX2-5, HHEX, TREX1, KCNIP3, ST18, GATA1, CDC5L |
| protein-lipid complex | cellular component | DBI, PEX3 |
| proteinaceous extracellular matrix | cellular component | TIMP1, TGFB1, DCN, MMP2, MMP9, VEGFA, ANOS1, VWF, TFPI2, SERPINA1, TGFBR3, ADAMTS1, ADAMTS5, BMP4, MMP12, FN1, MMP7, ADAMTS20, LGALS3BP, SHH, FLRT3, ANXA2, ECM1, TIMP2 |
| proton-transporting ATP synthase complex | cellular component | ATP5F1B |
| proton-transporting ATP synthase complex, catalytic core F(1) | cellular component | ATP5F1C, ATP5F1B, ATP5F1E, ATP5F1D |
| proton-transporting ATP synthase complex, coupling factor F(o) | cellular component | MT-ATP6, MT-ATP8, ATP5PB, DMAC2L, ATP5MC3, ATP5PF, ATP5PD, ATP5MC1, ATP5MC2, ATP5MG, ATP5MF, ATP5ME |
| proton-transporting two-sector ATPase complex | cellular component | ATP6V1E1, ATP6V1A, ATP6V1C1, ATP6AP1, ATP6V1F |
| proton-transporting two-sector ATPase complex, catalytic domain | cellular component | ATP6V1E1, ATP6V1E2 |
| proton-transporting two-sector ATPase complex, proton-transporting domain | cellular component | ATP5MC3, ATP5MC1, ATP5MC2, ATP6V0B, ATP6V0C |
| proton-transporting V-type ATPase complex | cellular component | ATP6V1D |
| proton-transporting V-type ATPase, V0 domain | cellular component | ATP6V0A2, ATP6V0E1, ATP6V0E2, ATP6V0D1, ATP6V0B, ATP6V0A4, TCIRG1, ATP6V0C, ATP6V0A1 |
| proton-transporting V-type ATPase, V1 domain | cellular component | ATP6V1B1, ATP6V1B2, ATP6V1A, ATP6V1C1, ATP6AP1, ATP6V1F, ATP6V1C2 |
| proximal dendrite | cellular component | KCNAB1, MAP2, PPP5C, GIGYF2 |
| proximal neuron projection | cellular component | GJC2, SYT5, MAP2, TRIM46 |
| Prp19 complex | cellular component | XAB2, HSPA8, PLRG1, CTNNBL1, RBM22, PRPF19, SYF2, BCAS2, ISY1, U2AF2, POLR2A, CDC5L, CRNKL1 |
| pseudopodium | cellular component | MAPK3, MAPK1, RAF1, CAPN2, RAB25, KLHL41, ACTN2, CNP, ACTN1, MSN, VAMP7, LDB3, ACTN3, ACTN4, MYOZ1 |
| pseudopodium membrane | cellular component | RAB25 |
| PTW/PP1 phosphatase complex | cellular component | WDR82, PPP1R12A, PPP1CB, PPP1R10 |
| Pwp2p-containing subcomplex of 90S preribosome | cellular component | UTP6, PWP2, WDR36, UTP18 |
| pyruvate dehydrogenase complex | cellular component | PDHA1, PDHX, PDHB, DLAT |
| pyruvate kinase complex | cellular component | PKM |
| R2TP complex | cellular component | RUVBL2, RUVBL1, PIH1D2, RPAP3 |
| Rab-protein geranylgeranyltransferase complex | cellular component | CHML, RABGGTB |
| Rad17 RFC-like complex | cellular component | RAD17 |
| Rad51B-Rad51C-Rad51D-XRCC2 complex | cellular component | XRCC2, RAD51C, RAD51B, RAD51D |
| Rad51C-XRCC3 complex | cellular component | RAD51C, XRCC3 |
| Rad6-Rad18 complex | cellular component | RAD18 |
| radial spoke | cellular component | RSPH9, RSPH6A, CFAP206 |
| RAVE complex | cellular component | DMXL1, DMXL2, ROGDI |
| Rb-E2F complex | cellular component | E2F1, RB1 |
| rDNA heterochromatin | cellular component | BAZ2A |
| receptor complex | cellular component | EGFR, EGF, VDR, TNFRSF1A, ERBB2, FLT1, APP, ITGB1, FGFR1, LEPR, TGFBR3, INSR, IGF1R, NTRK1, DDR1, NR1H3, GABRB1, RYK, ROR1, NBR1, IL13RA2, GPR160, OLR1, ACVR1B, CSF3R, ALK, GPR37L1, ITGB5, LTK, PTH1R, PTPRA, EPHB2, TIE1, ACVR1, TAS1R2, KLRC1, FLT4, BMPR1A, IL12RB1, GPR119, RAMP2, LDLR, TAOK2, ROS1, CNTFR, NOTCH1, IL13RA1, VLDLR, ACVR2B, CR1L, RNMT, ADRB2, ADRB3, KLRC2, MTNR1A, TEK, NTRK2, PKD2L1, SLITRK5, GABRA5, EPHB1, ITPR3, IL23R, IMPG2, CRLF2, PIGR, ADRA2A, ITGB6, PEX5L, EPHA6, LIFR, PLA2R1, GABRG1, ACVR1C, ITGB3, ITGB4, PTPRB, LRP2, NR1H4, GHR, PTPRN2, ADGRV1, KCTD12, GPR61, TGFBR1, CR2, EPHA4, GPRC5A, CRLF1, EPHA1, ITGB7, ACVR2A, TRPC1, CD200R1, GPR101, GPRC5B, NOTCH3, P2RX6, RAMP3, LRP5, ITGB2, NPR1, ERBB3, LRP1, ITPR2, TRADD, ITLN1, LRP1B, TM7SF2, RET, PDGFRB, EPHA2, IL2RG, TGFBR2, EPHA7, PLXDC1, TLR7, TSHR, MST1R, IL11RA, KCTD8, OSMR, IL12RB2, GPRC5C, GFRA3, PDGFRA, ENG, EPHA3, EPHA8, ACVRL1, ADCYAP1R1, IL5RA, IL31RA, GPR84, NRP1, RAMP1, FGFR4, EBI3, CAPRIN2, GABRQ, GFRA2, CSF1R, INSRR, ITGA3, EPHB3, |
| RecQ family helicase-topoisomerase III complex | cellular component | RMI1 |
| recycling endosome | cellular component | TNF, CFTR, TF, ITGB1, HFE, LMTK2, AQP2, OPTN, ACKR4, TUBGCP4, RAB11A, MLC1, RABEP1, PHETA2, RAB29, RAP2B, VPS52, RAB11FIP5, STX8, SLC31A2, ENTR1, VTI1B, INPP5F, DYNC1I1, AP1G1, FCHSD2, RAB4A, DENND6A, PHETA1, VAMP8, ARFGEF2, TFRC, RAB25, VPS33B, VIPAS39, ABCG1, SLC9A7, PLA2G3, RABGEF1, MYO5A, SLC30A10, LZTR1, ACKR3, SLC9A9, GGA3, STX7, ULK1, RAB14, ST8SIA2, AMOTL2, MCTP1, AVL9, ATP9A, RAN, ANK2, VAMP3, RAB11B, COMMD1, TPP1, TUBG1, CLCN3, VPS53, RAB11FIP1, DENND6B, TNIK, ATP11B, RNF11, TBC1D12, EEA1, ATG9A, SGK3, CLTCL1, SNF8, VPS50, MYO5B, ATP11A, SORL1, VPS51, OR2A4, RAB4B, CLN3, ARF6, KCNK1, SLC31A1, PLA2G5, UNC13D, SLC9A6, VPS16, PLEKHJ1, NISCH, RAP2A, CD22, CLCN4, ACKR1, C1orf210, GPR161, BACE1, RAB8A, TMUB1, RAB17, GRIA1, RAB11FIP3, USP6, ITSN1, MICALL2, TBC1D17, ARHGAP44, MCOLN2, TBC1D14, RASSF9, ACKR2, PANK1, GPER1 |
| recycling endosome lumen | cellular component | PDLIM4 |
| recycling endosome membrane | cellular component | RAB11FIP2, STX12, OPTN, RAB11A, RAP2B, RAB11FIP5, ACAP1, GRIPAP1, VTI1B, RAB4A, RAB11FIP4, VAMP8, RAB8B, RAB35, SLC9A7, CD274, SYT5, LZTR1, SLC26A7, EHD4, GGA3, PACSIN2, FZD7, RAB14, INPP4A, CMTM6, SCAMP1, VAMP3, RAB11B, PLEKHB2, RAC1, ATP11B, SCAMP2, ABHD17B, SORCS2, ZDHHC2, BOK, SORL1, ARF6, EHD2, SLC9A6, NDRG1, RAP2A, PDLIM4, EHD3, RAB8A, RAB17, NSG1, SLC39A4, SCAMP4, GRIA1, RAB11FIP3, BAIAP3, ABCB11, MICALL1, ABHD17A, MCOLN2, HLA-F, CLIP3 |
| replication fork | cellular component | TP53, DNMT1, UBE2B, H2AFX, NBN, XRCC2, POLH, HMCES, RAD51C, BCL6, DMAP1, MRE11, RTF2, UHRF1, TP53BP1, RAD51B, RAD51D, BLM, XRCC3, PRIMPOL, RAD18, DONSON |
| replication fork protection complex | cellular component | TOP1, TIPIN, CDC45, TIMELESS, GINS2, WDHD1, MCM10 |
| replisome | cellular component | PCNA, DONSON |
| RES complex | cellular component | RBMX2 |
| respiratory chain | cellular component | CYCS, MT-CO1, MT-CYB, MT-ND4, NDUFC2, MT-ND5, NDUFA6, NDUFB9, NDUFA4, NDUFB5, NDUFS6, NDUFB6, UQCRFS1, HIGD1A, UQCRB, NDUFC1, UQCRC2, NDUFS4, NDUFA8, NDUFB8, NDUFS2, NDUFB10, NDUFA1, NDUFA2, NDUFB1, NDUFS1, NDUFB4, NDUFA12, NDUFA5, NDUFAB1, UQCR11, NDUFA7, NDUFA11, HIGD2A, NDUFC2-KCTD14, NDUFA3, NDUFV2, UQCRQ, NDUFB11, MT-CO2, NDUFA9, UQCRHL, NDUFV3, UQCRC1, UQCR10, NDUFB2, NDUFS8, CYC1, NDUFB7, NDUFA10, UQCRH, TTC19, FOXRED1, MT-ND4L, MT-ND6, NDUFS5, NDUFS7, MT-ND1 |
| respiratory chain complex I | cellular component | NDUFA5 |
| respiratory chain complex II | cellular component | SDHB, SDHC |
| respiratory chain complex III | cellular component | MT-CYB |
| respiratory chain complex IV | cellular component | MT-CO1, MT-CO3, COX7B2, COX7B, COX6B1, COX8A, MT-CO2, COX8C |
| retromer, cargo-selective complex | cellular component | VPS26A, VPS29, VPS26B, VPS35 |
| retromer, tubulation complex | cellular component | SNX6, SNX2, SNX5 |
| rhabdomere | cellular component | MERTK |
| ribbon synapse | cellular component | NPHP4, ATP2A2, CTBP2, UNC13B |
| ribonuclease H2 complex | cellular component | RNASEH2B, RNASEH2A |
| ribonuclease MRP complex | cellular component | POP4, POP1, RPP25, RPP25L, POP5, POP7 |
| ribonuclease P complex | cellular component | POP4 |
| ribonucleoprotein complex | cellular component | FMR1, RO60, HSPA8, RPL4, RPL5, HNRNPF, RPS3A, RPL27, RPS7, RPS4X, RPS6, HNRNPU, HNRNPA0, DDX1, RPLP0, NPM1, CSNK1A1, HNRNPM, RPS8, RPL7A, G3BP1, DYRK1A, ZC3H14, DDX43, HNRNPR, HNRNPA1, XRCC5, RPL7, RBMS1, IQGAP1, HNRNPA3, GRSF1, CELF5, EPRS1, RPS9, HNRNPD, RBM45, RBM12, XPO1, SYNCRIP, SSB, HNRNPH3, RPS5, APOBEC3F, HNRNPA2B1, RPS3, TIA1, NUP62, RPL13A, ILF2, RUVBL2, CASC3, TRA2B, RBM3, NCBP1, ELAVL2, MRPL10, HNRNPAB, YBX1, ILF3, EEF2, SNU13, TRA2A, ELAVL3, NOL8, EFL1, RBM28, TIAL1, RNF135, HNRNPH2, NFATC2, RBMS2, DYRK2, RPL22, RBMS3, TEFM, CELF4, SRA1, HNRNPDL, LRPPRC, MEPCE, MRPL41, CELF2, ELAVL4, HNRNPH1, SNRPG, SLBP, CELF6, LARP6, RUVBL1, DDX53, SECISBP2L, RBM14, APOBEC3G, AGO2, TOP2B, PIH1D2, G3BP2, ZFP36, NUP98, ZFP36L1, RBM23, DDX17, SF3B4, PABPC5, RBM24, MSI1, EFTUD2, MYEF2, AGO1, NCL, GTF3C1, ERG, TRIM21, RPL26, MKRN3, LSM7, CBX5, CPSF6, L1TD1, SECISBP2, PARP4, JRK, PABPC4, PABPN1, RBMXL1, NSRP1, RBM38, AKAP8L, ACTN4, EIF4A3, EEFSEC, RBM42, IGF2BP1, IGHMBP2, LRRK2, RBM12B, ATXN2, HSPA1A, HSPA1B, TDRD1, |
| ribonucleoprotein granule | cellular component | HNRNPL, TDRD7, FXR1, GRSF1, FASTKD5, FASTKD2, FXR2, DHX30 |
| ribonucleoside-diphosphate reductase complex | cellular component | RRM2, RRM1 |
| ribose phosphate diphosphokinase complex | cellular component | PRPS1L1, PRPS1, PRPSAP1, PRPSAP2 |
| ribosome | cellular component | APEX1, MRPS14, RPL4, RPL3, RPL5, RPS10, DAP3, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, MRPS15, RPL24, RPL6, RPL10L, MRPL20, MRPL47, MRPL17, MRPL22, RSL24D1, RPLP0, MRPL3, CANX, RPL29, RPL15, RPS8, RPL7A, RPL32, RPS21, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, MRPL16, MRPS23, SERP1, RPL7, RPL13, RPS18, RPS13, RPL11, RPL19, HSPA14, MRPL14, MRPL43, RPL39L, PTCD3, MRPL46, MRPS17, RPL35A, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, MRPL49, RPS27L, MRPS30, MRPS18A, MRPL39, MRPL15, RPS2, NCK1, RPL9, RPS19, RPS5, MRPL19, RPS25, RPL30, RPS27A, RPL38, RACK1, MRPL58, MRPL51, DNAJC21, MRPS24, MRPL35, MRPL27, RPS6KL1, RPS3, RPL13A, RPL35, RPL36AL, MRPS7, MRPS18C, RPLP1, RPS12, RPS27, RPL39, MRPL10, MRPL48, MRPL40, RPS4Y1, RPL8, GCN1, MRPL37, MRPS33, MRPL11, RPL3L, MRPS28, MRPL33, MRPS26, MRPL23, MRPL38, MRPS12, RPL27A, MRPS25, RPL18A, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, MRPL54, MRPS27, MRPL57, AURKAIP1, MRPS16, RPL14, RPL37, RPS15A, RPS24, RPS28, MRPL21, MRPL55, MRPL41, MRPL53, RPL36, RPL10, MRPL34, |
| RIC1-RGP1 guanyl-nucleotide exchange factor complex | cellular component | RIC1, RGP1 |
| ripoptosome | cellular component | CASP8, FADD, CFLAR, CASP10, TICAM1 |
| RISC complex | cellular component | DICER1, AGO4, DCP2, TARBP2, AGO3, EIF4E, DDX6, AGO2, TNRC6A, AGO1, LIMD1, SND1 |
| RISC-loading complex | cellular component | DICER1, AGO4, PRKRA, TARBP2, AGO3, AGO2, ZFP36, AGO1 |
| Rix1 complex | cellular component | TEX10, WDR18 |
| RNA cap binding complex | cellular component | NCBP2, NCBP1, NCBP3 |
| RNA nuclear export complex | cellular component | RAN |
| RNA polymerase complex | cellular component | POLR2D, CRCP |
| RNA polymerase I complex | cellular component | POLR1F, POLR1B, POLR1H, POLR2F, POLR1C, POLR1E, POLR1A, POLR1D, POLR2L, POLR2E, POLR2K, POLR2H |
| RNA polymerase I core factor complex | cellular component | TAF1B |
| RNA polymerase I transcription regulator complex | cellular component | TAF1A |
| RNA polymerase II transcription factor complex | cellular component | NR5A2, VDR, NR5A1, HIF1A, STAT3, PPARG, GATA4, NR1H3, HNRNPU, TFDP1, NR1D2, E2F5, DDIT3, MAX, E2F4, CARM1, RARB, SFPQ, DR1, SMAD4, PPARD, ASCL3, GTF2B, ASCL4, HNRNPAB, ASCL2, HOXB9, MXI1, E2F3, NONO, ATF4, ASCL1, E2F2, NEUROD1, NFYC, PBX1, NR1H4, HIPK2, NFYA, E2F6, TFDP2, NFYB, NR1D1, POU4F1, HYAL2, E2F7, E2F8, MXD3, POU2F1, ATF6B, RXRG, DRAP1, RARG, NKX2-5, TCF15, PPARA, THRA, WWOX, POU2AF1, RARA, NR1H2 |
| RNA polymerase II transcription repressor complex | cellular component | DDX20, ETV3, TBX15 |
| RNA polymerase II, core complex | cellular component | POLR2F, POLR2G, POLR2B, POLR2D, POLR2J, POLR2L, POLR2E, POLR2K, POLR2I, POLR2C, POLR2H, POLR2A, POLR2M |
| RNA polymerase II, holoenzyme | cellular component | RPRD2, RECQL5, MYO6, RPRD1A, RPRD1B, POLR2M |
| RNA polymerase III complex | cellular component | POLR2F, POLR3F, POLR1C, POLR3K, POLR1D, POLR3A, POLR3H, POLR2L, POLR2E, POLR2K, POLR3C, POLR3GL, POLR3D, POLR2H, POLR3E, CRCP, POLR3B |
| RNA polymerase transcription factor SL1 complex | cellular component | TAF1B, TAF1D |
| RNA-directed RNA polymerase complex | cellular component | TERT |
| rod photoreceptor outer segment | cellular component | GUCY2F, ATP1A4, RD3, TMEM237, SPATA7 |
| rod spherule | cellular component | REEP6 |
| rough endoplasmic reticulum | cellular component | BGLAP, APP, PTGDS, NCOA2, TP63, RPL4, RPL27, RPL6, TRAM1, CANX, RPS21, BAIAP2, ZC3H12A, RPS23, SEC62, STAU1, CYBB, RPN2, RANGRF, RPN1, SUCO, STX17, F12, CKAP4, TRAM2, HM13, GLUL, ARSB, PSEN1, RAB14, HGFAC, RPS29, TMCC1, NCF1, RPS28, TMEM97, LRPAP1, RPL18, CCDC47, MT3, KCNJ2, PLOD3, SFTPD, SPPL3, HCRT, ADCYAP1R1, SEC61A1, FKRP, HTR5A, TRAM1L1, P2RX3, NUCB1, PCSK9, CA4, CDKAL1, MYOC, LIN28A |
| rough endoplasmic reticulum lumen | cellular component | LRPAP1, VTN, EDN1 |
| rough endoplasmic reticulum membrane | cellular component | PLOD1, ZC3H12A, NAT8L, SUCO, MACO1, PLOD2, TMEM97, CCDC47, PI4KB |
| RQC complex | cellular component | LTN1, NEMF |
| RSC-type complex | cellular component | SUZ12, PBRM1, EN1, EN2 |
| RSF complex | cellular component | SMARCA5, RSF1 |
| ruffle | cellular component | GNAS, ITGB1, ITGA5, MEFV, EZR, ANXA2, NF2, AIF1, S100A11, RASA1, ACAP2, COBL, ATP6V1B2, MTM1, MTSS2, PALLD, BAIAP2, IQGAP1, ALS2, NCKAP1, CYTH3, ARHGEF7, C2CD5, SLC9A3R1, WIPF1, CSPG4, RAB5A, CTTN, RINL, S100A6, BCAR1, AMOT, RAB22A, MYO5A, PIP5K1A, SNX5, MTSS1, KLHL41, ROCK1, LAYN, ARAP3, LIMA1, DBNL, TLN2, MYO6, FRMD4B, SNX9, FSCN3, ITGB1BP1, CDK6, FGD6, SAMSN1, KLHL2, ACTN1, CLIP1, ARHGAP18, INPP5K, WASF2, CYFIP1, KIF18A, RDX, MYADM, PARD6A, KNSTRN, NME2, TESC, MYO10, CD2AP, S100B, CAPG, APPL2, ASAP3, FGD4, TNFRSF12A, PDLIM7, PODXL, LCP1, ARF6, PDPN, PDGFRB, FGD2, MYO1C, MYH9, APPL1, TLN1, PTK6, CARMIL2, INPP5E, FSCN1, FGD5, MTMR14, VIL1, ARHGEF26 |
| ruffle membrane | cellular component | HSP90AA1, KANK1, CIB1, ITGB1, ITGA5, ITGAV, SRC, EZR, TWF1, SPRY4, TPM1, NF2, AIF1, PTPRJ, ARF4, EEF1A1, MTSS2, MTMR6, PPP1R9B, C2CD5, PSD3, JCAD, CORO1C, RPS3, DLC1, PLEKHA1, MACF1, PLEK, ARHGAP45, FERMT1, ARHGEF4, SNTG1, AIF1L, RASGRP2, WWC1, PIP5K1A, DIAPH1, PDE9A, TIRAP, PSD2, PACSIN2, MYO6, MTMR9, EPB41L5, ITGB3, APC, EPS8, TIAM1, CDKL5, RAC1, THEM4, KSR1, SPATA13, INPP5K, PLEKHO1, ARHGEF2, SH3YL1, TESC, APPL2, PSD, SPRY2, FGR, LCP1, PDPN, CLASP2, EPHA2, FGD2, PSD4, MYO1C, NME1, SH2D3C, RAB34, ABCA7, TLN1, PIP5K1C, AKT2, EPS8L1, PDXP, ADGRE2, HIP1R, FAM107A, FGD5, PACSIN1, PDE4A |
| ryanodine receptor complex | cellular component | RYR1 |
| RZZ complex | cellular component | ZW10, ZWILCH, KNTC1 |
| SAGA complex | cellular component | TADA3, TAF12, ENY2, TAF9B, SUPT20H, USP22, TAF6L, TAF6, SGF29, TAF9 |
| SAGA-type complex | cellular component | TADA1, HCFC1, SUPT20H, USP22, TADA2A, SGF29 |
| sarcoglycan complex | cellular component | SGCE, SGCB, SGCD, SGCA, SGCZ |
| sarcolemma | cellular component | FAS, CIB1, ITGB1, ANXA2, ANK1, ANXA6, ANXA5, SLC2A5, CAMK2D, DES, ANK3, DMD, SGCE, CLCN1, PLEC, BVES, CORO1C, NOS1AP, UTRN, POPDC3, KCND3, FXYD1, ANXA1, RYR1, RYR2, SNTG2, CACNA1C, PEMT, SLC9A1, SGCB, DTNA, MLIP, PDE9A, CAV3, GHRHR, FLNC, DTNBP1, SLC38A2, PSEN1, CAV2, SLC8A3, AHNAK, BGN, PGM5, FLOT1, ATP1A2, ANK2, DLG1, KCNB1, SLMAP, SGCD, COL6A1, PPP3CA, CIB2, KRT19, SLC8A1, OBSCN, VCL, POPDC2, LAMP1, SLC2A4, ATP1B1, AQP1, SSPN, COL6A2, PPP3R1, SNTB1, STAC2, ATP1A1, KRT8, FGF6, DAG1, SYNC, CACNB1, CACNG1, FKRP, DYSF, GOT2, COL6A3, SNTA1, AHNAK2, STAC3, TRIM72, CCDC78, CASQ1, SCN5A, SGCA, SLC8B1, SGCZ, CACNB2, CAV1 |
| sarcomere | cellular component | MMP2, MYH7, TPM1, HDAC4, MTM1, TCAP, MYOM2, ABRA, NEB, CORO1C, ANKRD2, RYR2, LMAN1, PSMA6, ARF1, MYBPC3, ACTC1, MYOM3, DUSP27, ACTN2, TTN, SQSTM1, MYPN, ABCC9, CALM1, CALM2, CALM3, PYROXD1, ACTN1, CSRP3, MTMR12, PARVB, CAPZB, HABP4, DCTN4, ILK, TIMP4, MYL2, ARHGEF25, MYO18B, MYL3, MYH3, MYH6, LMOD2, SYNE1, MYH8, TMOD1, MYOM1, MYLK2, LMOD1, MYOZ2, MYH2 |
| sarcoplasm | cellular component | PLEC, FABP3, MEF2C, FLNC, DTNBP1, SLC8A3, SPOCK1, HABP4 |
| sarcoplasmic reticulum | cellular component | XDH, CACNA2D1, ANK1, DMPK, ATP2A2, CAMK2B, CAMK2D, CALU, SRI, ANK3, HSP90B1, TRDN, HAX1, CASQ2, RYR1, MANF, RYR2, SLN, SRL, IRAG1, THBS1, AGL, KLHL41, ITPR3, JPH2, SGCD, MRLN, PLN, MTMR12, FKBP1B, HK2, ASPH, ITPR1, SLC2A4, ATP2A3, ITPR2, SYNE2, POMT1, NOL3, HRC, THBS4, CAMK2G, JSRP1, JPH1, ATP2A1, CLEC18B, CCDC78, CALR, CASQ1, TMEM109, ART1, STIM1, CMYA5, S100A1, AKAP6 |
| sarcoplasmic reticulum lumen | cellular component | CALU, HSP90B1, TRDN, CASQ2, MANF, SRL, ASPH, HRC, CALR, CASQ1 |
| sarcoplasmic reticulum membrane | cellular component | DMPK, ATP2A2, CAMK2B, CAMK2D, SRI, NOS1AP, TRDN, CASQ2, RYR1, RYR2, SLN, CHERP, TMEM38B, KLHL41, JPH2, MRLN, PLN, FKBP1B, ASPH, ATP2A3, ITPR2, SYNE2, HRC, CAMK2G, JSRP1, JPH1, ATP2A1, CASQ1, TMEM109, ART1, STIM1 |
| SCAR complex | cellular component | WASF3, NCKAP1, ABI2, CYFIP2, SRA1, WASF2, CYFIP1, ABI1, WASF1, NCKAP1L |
| Scc2-Scc4 cohesin loading complex | cellular component | MAU2, NIPBL |
| SCF ubiquitin ligase complex | cellular component | FBXO38, USP47, SKP1, FBXL5, FBXL22, FBXW7, FBXO17, FBXL12, BTRC, ARIH1, FBXL13, FBXO9, CKS1B, FBXO2, PRKN, CUL1, SPSB3, FBXO33, FBXO4, FBXL4, FBXO32, FBXL16, CUL5, FBXO39, CACYBP, DMAC2, FBXL17, FBXL3, SKP2, FBXO25, CUL2, AMN1, FBH1, FBXO6, FBXL6, CCNF, FBXW8, RBX1, SPSB1, TRIM21, FBXL19, FBXW5, SPSB2, FBXO44, FBXL2, FBXO7, CKS2, FBXL7, FBXO31, FBXL14, LRRC29, SPSB4, FBXL20, FBXO45 |
| Schaffer collateral - CA1 synapse | cellular component | RAB11A, AKAP12, BAIAP2, NPTN, NEFH, SH3GL2, CACNG2, DVL1, GIPC1, PTPRA, STX3, GSG1L, DGKB, CPLX1, CTNND1, BCR, PFN2, ABR, SYNPO, GHSR, CACNG3, STXBP5, LRFN2, NTNG1, DGKI, SYP, SYN1, DTNBP1, BSN, DCC, SRGN, SLC30A1, ADCY8, PPP3CA, ACTG1, NTNG2, PRKCZ, APBA2, EPHA4, ITPR1, APBA1, SYN2, LRRC4, GABBR1, CASK, PLG, EFNB2, CDH11, EPHA7, ADRB1, CDK5, PTPRS, CHRM1, PRKAR1B, ADORA2B, LRRTM2, P2RX3, RNF216, SHANK1, SH3GL1, WNT7A, GRM5, INA, FBXL20, NEFL, GRM1 |
| Schmidt-Lanterman incisure | cellular component | PTEN, ANXA2, AKR1B1, MPDZ, JAM3, SIRT2, MAG, NCMAP |
| Schwann cell microvillus | cellular component | EZR, AKR1B1, NFASC |
| Scrib-APC-beta-catenin complex | cellular component | CTNNB1, SCRIB |
| Sec61 translocon complex | cellular component | ARL6IP1, SSR4, SEC61B, SEC61A2, SEC61A1 |
| Sec62/Sec63 complex | cellular component | SEC63 |
| secondary lysosome | cellular component | CRHBP |
| secretory granule | cellular component | SOD1, TGFB1, IL1B, TGFB3, VEGFA, FAS, BRCA2, TRH, LTF, PLAT, HSPD1, CDC42, SPACA3, OXT, ELANE, ACPP, PLA2G2A, PAM, SLC30A5, BAIAP2, SYPL1, RAB11FIP5, KLK9, RAB27A, CTSV, SNX10, SNAPIN, STX3, RNPEP, SYTL4, SYT1, MYO5A, RAB27B, FSTL3, SCG5, THBS1, CYBA, FSTL4, CTSG, CRHBP, GHRHR, SLC30A8, KLK8, CPA3, RAB3B, BPIFA2, PCSK2, PRSS58, SRGN, VAMP3, KLK15, GARS1, CLCN3, PTPRN2, KLK2, CFP, VAMP7, OLFM4, EBAG9, ATP7A, STXBP3, PLA2G1B, KLK13, SCG2, KLK10, CARTPT, HILPDA, AVP, MPO, RPH3A, KLK5, HCRT, KLK1, ANGPTL6, CCL28, NPPC, SYT9, CHGB, GAL, POMC, CBARP, TMPRSS4, KLK12, STXBP2, KLK6, KLK11, RPH3AL, EXOC3L1, KLK4, KLK7 |
| secretory granule lumen | cellular component | GHRL, TF, HSPA8, PSMB1, PSMC2, EEF1A1, DERA, CAB39, DDX3X, PSMA2, PSMA5, COTL1, PSMB7, XRCC5, GYG1, PSMD6, PSMD14, CFD, GDI2, PSMD7, HUWE1, ARPC5, CSTB, ARHGAP9, SRP14, PNP, GRP, PKM, ARHGAP45, EEF2, PSMC3, EPX, XRCC6, SERPINB1, AGL, DEFA5, ROCK1, OSTF1, DBNL, ALDOA, APRT, HMGB1, SCG3, CCT8, APOA1, PSMD12, CDA, CAND1, GPI, PSMD2, CYFIP1, FCN1, ALOX5, VCL, S100A8, ALAD, NME2, S100P, AMPD3, PGM2, BIN2, PYGL, FGR, SERPINI1, CRISPLD2, PPIE, PSMD3, PCSK1, PYCARD, IMPDH2, HSPA6, IMPDH1, GHDC, ALDOC, PFKL, GMFG, ACTR1B, MMTAG2, POMC, INS, DBH, CTSH, HK3, MVP, AHSG, PPIA, PSMD13, SERPINA3 |
| secretory granule membrane | cellular component | MYRIP, PAM, RAB18, SIRPB1, SLC2A3, CD38, SLC30A5, CD55, IQGAP1, IQGAP2, ORMDL3, RAB27A, COPB1, ATAD3B, SERPINB6, CD93, CD58, FABP5, VAMP8, RAB6A, RAB31, HVCN1, AP2A2, RHOG, ABCA13, CLEC4C, RAB27B, DIAPH1, SYCN, ITPR3, SLC30A8, PTPRC, CXCR2, SCG3, RHOF, RAB7A, EXOC3, TYROBP, RAC1, PTPRN2, RAB26, DYNC1LI1, VAMP7, TICAM2, B4GALT1, TMED10, ICA1, SVIP, FCGR3B, ITPR1, ITGAX, RAB4B, DOK3, STING1, ADGRE3, RAB5B, ITPR2, MOXD1, TMEM179B, MME, FCGR2A, CPE, CXCR1, ALDH3B1, NCKAP1L, SELL, PECAM1, PTAFR, TCIRG1, SYT9, SIGLEC9, DBH, ANPEP, TMEM184A, CA4, ADGRE5, RPH3AL, C5AR1, ATP6V0A1, RAB9B |
| secretory vesicle | cellular component | DYNLT1, RAB3D |
| Seh1-associated complex | cellular component | SEH1L |
| semaphorin receptor complex | cellular component | PLXNC1, NRP2, PLXNA1, PLXNA4, PLXNB3, NRP1, PLXNA3, PLXNB2, PLXNB1, PLXNA2, PLXND1 |
| senescence-associated heterochromatin focus | cellular component | CDKN2A, CBX3, HMGA2 |
| septin complex | cellular component | 39326, 41153, SEPTIN2, SEPTIN9, SEPTIN10, SEPTIN11, SEPTIN1, SEPTIN5, SEPTIN8, TMEM250, SEPTIN14, SEPTIN3, SEPTIN7 |
| septin cytoskeleton | cellular component | MAPK6 |
| septin ring | cellular component | SEPTIN2, SEPTIN9, SEPTIN10, SEPTIN11, SEPTIN1, SEPTIN5, SEPTIN8, TMEM250, SEPTIN14, SEPTIN3, SEPTIN7 |
| serine C-palmitoyltransferase complex | cellular component | SPTLC3, SPTLC1, SPTSSA, SPTLC2 |
| serine protease inhibitor complex | cellular component | SERPINB6, KLK8 |
| serine-pyruvate aminotransferase complex | cellular component | EEA1 |
| serine-type endopeptidase complex | cellular component | HTRA2 |
| serine-type peptidase complex | cellular component | F7 |
| serine/threonine protein kinase complex | cellular component | CAB39 |
| serotonergic synapse | cellular component | SLC6A4, HTR1B |
| serotonin-activated cation-selective channel complex | cellular component | HTR3B, HTR3A |
| Set1C/COMPASS complex | cellular component | DPY30, WDR82, ASH2L, CXXC1, RBBP5, HCFC1, WDR5, DYDC1, SETD1B, SETD1A |
| sex chromatin | cellular component | EED, PCGF2, SUZ12, MACROH2A1, RING1, RNF2 |
| sex chromosome | cellular component | SMC5 |
| Shc-EGFR complex | cellular component | EGFR, SHC1 |
| shelterin complex | cellular component | TERF2IP, POT1, TINF2, ACD |
| Shu complex | cellular component | SWSAP1 |
| signal peptidase complex | cellular component | SEC11A, SEC11C, SPCS3, SPCS1, SPCS2 |
| signal recognition particle | cellular component | SRP9, DERL2, SRP19, DERL1, SRP14, SRP54, SRP72, DERL3 |
| signal recognition particle receptor complex | cellular component | SRP9, DERL2, DERL1, SRPRA, RP9, DERL3 |
| signal recognition particle, endoplasmic reticulum targeting | cellular component | SRP9, SRP19, SRP14, SRP54, SRP72 |
| Sin3 complex | cellular component | SIN3A, MORF4L1, SINHCAF, HDAC2, SIN3B, SUDS3, ING2, CSNK2A1, RBBP4, HEY2, NCOR1, PHF12 |
| Sin3-type complex | cellular component | HDAC2, SUDS3, SAP130, PHF12, BRMS1 |
| site of DNA damage | cellular component | XRCC5, CBX1, CBX3, OARD1, NKX3-1, ERCC6, RPA1, POLK, RFWD3, SLFN11, WDR76, CUL5, EXD2, HROB, ELOA, ADPRS, CBX5, AUNIP, UBQLN4 |
| site of double-strand break | cellular component | H2AFX, RNF8, NBN, SLF2, ARPC1A, RBBP8, ACTR3, POLH, ARPC3, PHF1, RPA2, RNF168, WDR70, PRPF19, ARPC5, SHLD2, SMC5, RNF138, KDM4D, RFWD3, WRAP53, TIMELESS, PARP3, MRE11, SMARCAL1, SAMHD1, HUS1, RNF169, SLF1, SMCHD1, FH, RPA3, SHLD1, CNTD1, MAD2L2, ATF2, ACTR2, TP53BP1, RIF1, RAD50, CGAS, HUS1B, SIRT7, SMARCAD1, STN1, WAS, ARPC4, ZBTB7A, APLF, HELB, PAXX, RAD18, TP53 |
| site of polarized growth | cellular component | COTL1, CTTN, DBNL, FRY, HCLS1, FRYL |
| Ski complex | cellular component | WDR61, TTC37, SKIV2L |
| SLIK (SAGA-like) complex | cellular component | TAF12, TAF6L, TAF6 |
| slit diaphragm | cellular component | IQGAP1, PPP3CA, F11R, PODXL, NPHS1, MAGI2, KIRREL2 |
| Slx1-Slx4 complex | cellular component | SLX1A, SLX4 |
| SMAD protein complex | cellular component | SMAD4, HMGA2, SMAD2, SMAD9, SMAD3, SMAD5 |
| small nuclear ribonucleoprotein complex | cellular component | SNRPN, ARFGEF1, SNRPB2, SLU7, SNRPE, SNRPB, GEMIN4, SNRPD1, SNRPD2, SNRPG, PRPF8, TGS1, SNRPA1, LSM6, SNRPF |
| small nucleolar ribonucleoprotein complex | cellular component | NOP58, SNRNP40, NOP10, NHP2, NOP56, MPHOSPH10, LSM6, NAF1, SNRPF |
| small ribosomal subunit | cellular component | MRPS14, DAP3, RPS4X, RPS6, RPS21, MRPS9, RPS18, RPS9, RPS20, RPS23, RPS2, RPS5, RPS25, RPS27A, RACK1, RPS3, MRPS12, RPS16, RPS29, RPS15, MRPS16, RPS24, RPS28, UBA52, MRPS2, RPSA, MRPS6 |
| small-subunit processome | cellular component | UTP14C, RPS7, IMP3, NOP58, XRCC5, DCAF13, UTP11, NOP14, IMP4, SNU13, UTP6, NOP56, PWP2, WDR36, UTP4, KRR1, UTP23, UTP3, HEATR1, MPHOSPH10, FBL, PRKDC, EMG1, FCF1, UTP20, UTP18, NGDN, NOL10, UTP14A, DIEXF, NOC4L, TBL3, PDCD11, NOL6 |
| SMC loading complex | cellular component | MAU2, NIPBL |
| Smc5-Smc6 complex | cellular component | NSMCE2, SMC5, NSMCE4A, NSMCE3, NSMCE1 |
| SMN complex | cellular component | FMR1, STRAP, GEMIN6, GEMIN5, DDX20, GEMIN4, GEMIN8, SMN1, GEMIN7 |
| SMN-Gemin2 complex | cellular component | GEMIN5 |
| SMN-Sm protein complex | cellular component | STRAP, SNRPE, GEMIN6, SNRPB, GEMIN5, DDX20, GEMIN4, SNRPD1, SNRPD2, SNRPG, GEMIN8, SMN1, SNRPF, GEMIN7 |
| smooth endoplasmic reticulum | cellular component | APP, PRDX4, HSPA5, PPIB, CANX, SRI, JPH4, RYR1, RYR2, MYO5A, PSEN1, SLMAP, RPL10, GBA2, GABARAP, DNAJC3, SYVN1, HYOU1, KCNJ2, TH, CALR, CASQ1, MYO1D |
| smooth endoplasmic reticulum membrane | cellular component | HSD3B1, HSD3B2, PGRMC1, FTCD, STX17, SVIP, TTYH1 |
| smooth muscle contractile fiber | cellular component | IDO1, PECAM1, ACTA2 |
| SNARE complex | cellular component | STX12, SEC22B, USE1, SNAP23, GOSR1, STX8, STX10, STX5, VTI1B, SNX4, BNIP1, STX3, VAMP8, BET1L, STX18, CPLX1, VAMP1, STXBP5, SNAP29, STX17, STX7, VAMP4, STX1B, SNAP25, VAMP3, STX16, BET1, VAMP7, SNAP47, GOSR2, BLOC1S6, NAPA, SYN2, TSNARE1, VTI1A, STX4, STX11, YKT6, DOC2B, NAPB, STXBP5L, CPLX2, CPLX3, NAPG |
| snRNA-activating protein complex | cellular component | SNAPC1, SNAPC4, SNAPC3 |
| sodium channel complex | cellular component | SCN1B, SCNN1G, SCN2A, SCN1A, SCNN1A, TRPM4, SCNN1B |
| sodium:potassium-exchanging ATPase complex | cellular component | FXYD1, FXYD4, ATP1A4, ATP1A3, ATP1A2, ATP1B1, FXYD2, ATP1A1, ATP1B2, ATP1B3, ATP4B |
| somatodendritic compartment | cellular component | CACNG2, LDLR, RAB5A, CACNG3, SNAP25, TIAM1, TMEM108, CACNG4, GRID2, STX4, JAM2, NSG1, GRIA1, MAP1B, SLC4A10 |
| sorting endosome | cellular component | KDR, LDLR, ARHGAP1, CLTCL1, PTPN1, NRP1 |
| SOSS complex | cellular component | INTS3, NABP1, INIP, NABP2 |
| spanning component of membrane | cellular component | SLC12A2, NLGN4X, SLC15A2, NLGN2, NLGN4Y, TRPM4, SLC15A1 |
| spanning component of plasma membrane | cellular component | BMPR2, SLC24A4, SLC15A2, SLC4A4, NPC1L1, SLC24A3, CDHR5, TRPM4, CDHR2, AJAP1, SLC24A1 |
| specific granule | cellular component | LTF, SNAP23, ANXA3, CAMP, STX3, ANXA11, CLCN3, OLFM4, STXBP3, STX4, ADAM8, STXBP2 |
| specific granule lumen | cellular component | HPSE, RAB27A, ARMC8, CNN2, CAMP, ILF2, ORM1, ACAA1, PTPN6, CHI3L1, QSOX1, GGH, TCN1, CRACR2A, CANT1, TOLLIP, AOC1, CFP, OLFM4, CYFIP1, VCL, ERP44, CEP290, LRG1, CXCL1, ORM2, QPCT, SPTAN1, OSCAR, NEU1, HP, DEFA4, BPI, FOLR3, CTSZ, JUP, GHDC, FRK, GSDMD, DOCK2, MMP8, DNASE1L1 |
| specific granule membrane | cellular component | SLC2A5, LAMTOR3, ATP6V1D, SLC2A3, MLEC, RAP2B, OLR1, ORMDL3, SLC15A4, ATP8B4, SNAP23, CD47, CYBB, PLD1, CD93, AGPAT2, ANO6, VAMP8, CD59, PGRMC1, CD53, HVCN1, TOM1, STK10, TMEM63A, VAMP1, STOM, ITGAM, CYBA, CEACAM8, UBR4, HGSNAT, MCEMP1, CKAP4, CLEC12A, CMTM6, DEGS1, SCAMP1, DGAT1, SNAP25, PTPRB, HMOX2, MS4A3, TMEM30A, SLCO4C1, DNAJC5, ATP11A, MMP25, ATP8A1, SLC27A2, C3AR1, LAMTOR1, TMBIM1, ITGB2, CEACAM3, LAIR1, CEACAM1, CD33, FCAR, FPR2, ALDH3B1, BST1, TMC6, ADGRG3, TSPAN14, CLEC5A, CLEC4D, GPR84, ADAM8, KCNAB2, SLC44A2, LILRA3, MOSPD2, ITGAL, TRPM2, RAB37, AP1M1, CHRNB4, CD36 |
| spectrin | cellular component | SPTBN5, SPTBN1, SPTBN2, PRKCB, SPTB, SPTAN1, SPTBN4, EPB41L2 |
| spectrin-associated cytoskeleton | cellular component | ANK1, ANK3, RHBG, SPTBN1, SPTB, DMTN, EPB41 |
| sperm annulus | cellular component | 41153, 38231, SEPTIN2, DDX6, SEPTIN7 |
| sperm connecting piece | cellular component | PMFBP1, SPATA6, SPATA6L |
| sperm cytoplasmic droplet | cellular component | NME8, IFT172 |
| sperm end piece | cellular component | CABYR |
| sperm fibrous sheath | cellular component | AKAP4, PGK2, CABYR, SPA17 |
| sperm flagellum | cellular component | TXNDC8, TEKT3, DNAH1, 38231, IFT88, CFAP70, CFAP65, TTC29, MNS1, QRICH2, DNAH2, DNAH17, NME5, CCDC181, RPGR, TPPP2, DNALI1, SPACA9, CST11, ABHD2, CCR6, MROH2B, SAXO1, DNAI2, RSPH6A, CABCOCO1, TACR2, DNAH8, RNF38, AK8, ATP1B1, GAS8, ATP1A1, ATP1B3, DRD2 |
| sperm head | cellular component | CST11, PCDH11Y, ALDOA, TACR2, DEFB132, DNAJB1 |
| sperm head plasma membrane | cellular component | ADAM30 |
| sperm midpiece | cellular component | PACRG, CFAP69, SLC26A3, CFAP65, CCDC172, SLC9A3R1, LYZL6, PCDH11Y, DEFB1, ATP1A4, CCR6, SQSTM1, MROH2B, HYAL3, TACR2, GABARAP, SLC26A6, IFT172, IFT81 |
| sperm plasma membrane | cellular component | LYZL6, ABHD2, CCR6 |
| sperm principal piece | cellular component | AKAP4, CABYR, NME8, CATSPER4, PGAM4, SPA17, KIF2A, CCR6, CATSPERG, SLC9B2, CATSPERD, SCNN1A, ENKUR, IFT172, IFT81 |
| spermatoproteasome complex | cellular component | PSMA8, PSMB8, PSMB9, PSMB10 |
| spherical high-density lipoprotein particle | cellular component | PON1, CLU, APOA1, HPR, APOC3, APOM |
| spindle | cellular component | AURKC, BIRC5, CDK1, ERCC2, MAPK1, AKT1, ATM, NR3C1, HSPB1, HSPA2, RB1, MAK, CDC42, CDC20, 39326, 41153, KIF3B, DYNLT1, KATNB1, RASSF1, EMD, HNRNPU, CENPE, SEPTIN2, EFHC1, MZT2B, HAUS2, HECW2, KIF2A, EVI5, KIF20A, MYH10, RMDN3, NUP85, NUSAP1, ARL8B, ZW10, CBX1, NSUN2, CDC16, CBX3, DLGAP5, MAP7D1, RMDN1, PRPF19, SBDS, CEP170, CEP350, HAUS4, KIF15, CIAO2B, KATNA1, WDR73, TBCK, RMDN2, ARL2BP, BUB1B, RPS3, KIF14, KLHL22, SPECC1L, RAB11FIP4, FAM83D, ZNF207, DCTN3, HAUS5, ASPM, ARL3, MAEA, PRC1, PTP4A1, KIFC1, RCC2, UNC119, SIRT2, DIDO1, ACOT13, TPX2, DIAPH1, CSNK1D, CENPF, PKP4, ANXA11, STX1B, MICAL3, ANKRD53, TACC3, CALM1, CALM2, CALM3, PLK1, MZT1, NEDD9, TTC23L, KIF2B, AGBL5, CKAP2, TUBGCP3, MAP9, CEP162, MZT2A, MAP11, KIF20B, CYLD, CLTA, TUBG1, MAP1S, SHCBP1, ECT2, MAD1L1, TTK, NUMA1, HAUS6, SKA2, ARHGEF2, ARL8A, CEP295, KLHL21, MTUS1, JTB, CLTCL1, CLTC, CSPP1, TTC28, MAD2L2, PIN4, TPR, CKAP5, RIF1, FLCN, INVS, DCDC1, EML2, TTLL12, MAPRE1, E4F1, MID1, CLASP2, KIF4A, MAP2K5, TUBB8, CDCA8, SPOUT1, MMS19, PLEKHG6, |
| spindle matrix | cellular component | ZNF207 |
| spindle microtubule | cellular component | AURKC, BIRC5, CDK1, KIF3B, KIF3A, HAUS2, KIF2A, NUSAP1, CDC16, KIFAP3, ARL3, PRC1, NEIL2, CSNK1D, CALM1, CALM2, CALM3, PLK1, BOD1L2, BOD1, TUBG1, NUMA1, FAM161A, SKA2, CDC27, BOD1L1, CLASP2, KIF4A, PSRC1, SKA1, POLB, PARP4, TUBG2, CLASP1, AURKB, KIF11 |
| spindle midzone | cellular component | AURKC, APP, CDC42, CENPE, ARL8B, MAPRE3, KIF14, GEM, UNC119, PKP4, CDC6, PLK1, MAP9, KIF20B, ARL8A, RIF1, MAPRE1, CDCA8, AURKB, CTDP1, CENPV |
| spindle pole | cellular component | CCNB1, CTNNB1, ODF2, CDC20, RANGAP1, KATNB1, RASSF1, MAPK14, HNRNPU, IK, ABRAXAS2, EFHC1, DNAAF1, BCCIP, TUBGCP4, KIF2A, RAB11A, GPSM2, CEP19, RMDN3, PLK2, ZW10, PPP2CA, NEDD1, RMDN1, DSN1, BEX4, SBDS, NIN, SPDL1, VPS4B, KATNA1, WDR73, RMDN2, DYNC1I1, TNKS, NUP62, CETN1, CDK5RAP2, FAM83D, CEP85, ASPM, PRC1, TOPBP1, UNC119, SGO1, NUDCD2, TPX2, UMOD, CENPF, RAE1, PKP4, CDC6, KATNBL1, ANKRD53, CEP89, LATS2, TACC3, WDR62, CALM1, CALM2, CALM3, PLK1, MAD2L1, NEDD9, FRY, BOD1L2, CKAP2, TUBGCP3, IKBKG, RAD21, BOD1, KIF20B, CDC14B, ALMS1, CEP95, CEP63, CEP44, MAD1L1, DYNC1LI1, YPEL5, NUMA1, WDR60, RASSF10, MAPKBP1, LATS1, CSPP1, CEP128, POC1B, TTC28, BIRC6, KNSTRN, CKAP5, TBCB, DCTN4, BOD1L1, TBCCD1, TPT1, TUBGCP5, PLEKHG6, PSRC1, CKAP2L, TUBGCP2, PLK3, DDX11, TUBGCP6, AUNIP, AAAS, MTCL1, RGS14, IRAG2, NEK6, GOLGA2, TMEM201, CEP104, CDC25B, FBF1, TOPORS, CTDP1, KNTC1, NEK2, KIF11, FAM110C, KATNAL2, NEK7, TCTEX1D2 |
| spindle pole centrosome | cellular component | AURKC, EMD, ABRAXAS2, NPM1, DLGAP5, NSFL1C, NUMA1, UBXN2B, NUBP2, TBCCD1, SPOUT1, NDE1, MISP, TMEM201, AURKB |
| spine apparatus | cellular component | SYNPO, OPRD1 |
| spliceosomal complex | cellular component | SNRPN, PABPC1, XAB2, RBMX, HSPA8, HNRNPF, HNRNPU, IK, WAC, PPIL3, PLRG1, SNRNP70, HNRNPM, LSM3, DHX40, CTNNBL1, CWC15, HNRNPR, SF3B1, HNRNPA1, HNRNPA3, TXNL4A, RBM22, PRPF19, IVNS1ABP, HNRNPC, MTREX, MFAP1, DDX39B, FRG1, SNRNP35, DHX32, SNIP1, SNRNP40, TTF2, SRRM2, WBP11, SYNCRIP, CDC40, SNRPB2, HNRNPH3, PRPF18, DDX23, SNRNP25, C9orf78, SLU7, HNRNPA2B1, BUD31, CWC25, CASC3, PRPF6, TRA2B, RBM3, PHF5A, KHDC4, ZCRB1, U2AF1L4, PRPF31, SYF2, SNU13, SNRPE, PPP1R8, SF3B2, TRA2A, RBM28, DHX15, PRPF38A, ZNF830, RBM8A, WBP4, SNRPB, DDX41, ALYREF, AQR, SNRPD1, SF3B6, HNRNPDL, PRPF3, SNRPD2, RHEB, SUGP1, PNN, BCAS2, HNRNPH1, SNRPG, PRPF8, API5, USP39, MAGOHB, RNPC3, SNRPA1, PRPF4B, SNW1, SNRNP48, ZCCHC8, RBM17, LSM6, SF3A1, PPWD1, ISY1, SNRNP200, LSM8, SF3B3, SF3B4, ZRSR2, PPIH, U2AF1L5, U2AF1, SRSF2, EFTUD2, PPIE, NCL, SF3A3, ZMAT5, DHX16, SMNDC1, SNRPF, SF1, SRRM1, LSM7, LSM2, GPKOW, ESS2, U2AF2, HNRNPK, PRPF38B, RBMXL1, WDR83, YJU2, TFIP11, RALY, SART1, SNRPA, EIF4A3, SF3A2, CACTIN, SREK1, DHX35, LSM4, PRPF4, CDC5L, C |
| spliceosomal snRNP complex | cellular component | PRPF4 |
| spliceosomal tri-snRNP complex | cellular component | PRPF31, SNRPD1, SNRPG, LSM7, LSM4 |
| spot adherens junction | cellular component | PGM5 |
| SPOTS complex | cellular component | ORMDL3, ORMDL2, SPTLC1 |
| SREBP-SCAP-Insig complex | cellular component | SREBF2, INSIG1, INSIG2 |
| Ssh1 translocon complex | cellular component | SEC61G |
| STAGA complex | cellular component | TADA1, TADA3, TAF12, SUPT3H, SUPT7L, TAF6L, TAF5L, TAF10, KAT2A, TAF9 |
| stereocilia ankle link | cellular component | USH2A, USH1C, ADGRV1, WHRN, PDZD7 |
| stereocilia ankle link complex | cellular component | VEZT, USH2A, USH1C, ADGRV1, WHRN, PDZD7 |
| stereocilium | cellular component | STRC, MYO15A, ELMOD3, BBS2, SLC9A3R1, FCHSD2, SLC4A7, MYO3B, HOMER2, CALB1, USH1C, ESPN, EPS8, ADCY6, CIB2, LOXHD1, ADGRV1, RDX, MORN4, TPRN, MYO3A, TWF2, MPP1, MYO1C, RHOC, KPTN, FSCN2, ATP8B1, MYO7A, ESPNL, TSPEAR, WHRN, CDH23, PDZD7, PVALB, DOCK4, PCDH15, ZSWIM6, RIPOR2 |
| stereocilium base | cellular component | TPRN, MYO7A |
| stereocilium bundle | cellular component | MYO15A, IDO1, USH2A, TRPA1, ESPN, EPS8, MYO1C, LHFPL5, WHRN, DOCK4 |
| stereocilium membrane | cellular component | VEZT, USH2A, ADGRV1, MYO1C, RIPOR2 |
| stereocilium shaft | cellular component | FCHSD2 |
| stereocilium tip | cellular component | STRC, SLC9A3R1, MYO3B, HOMER2, USH1C, ESPN, EPS8, MORN4, MYO3A, TMC1, LHFPL5, ESPNL, WHRN, PDZD7, CEACAM16, TMC2 |
| storage vacuole | cellular component | CDC42, STX4 |
| stress fiber | cellular component | MYH7, 39326, 41153, TPM1, SIPA1L3, ROR1, CORO1B, SORBS1, SEPTIN9, MYH10, PALLD, FERMT2, PXN, MYH14, MYL12B, TPM3, CNN2, FLNB, PTK2, PDLIM1, BAG3, TPM4, SYNPO, PDLIM2, ABLIM1, AMOT, CYBA, TEK, LIMA1, PGM5, GAS2L1, TLNRD1, VANGL2, SYNPO2, NEBL, ACTN1, XIRP2, PRKCZ, FBLIM1, LPP, PDLIM5, DCTN4, LDB3, PDLIM7, SEPTIN11, LIMCH1, LCP1, ILK, GAS2L2, PDLIM4, MST1R, PDLIM3, MYO1C, MYH9, MYH6, MYLK, FHOD1, ACTN4, FAM107A, FSCN1, MICALL2, ABLIM3, TRIP6, ZYX, SEPTIN7, XIRP1 |
| striated muscle dense body | cellular component | FRG1 |
| striated muscle myosin thick filament | cellular component | MYBPC3, TRIM32, MYOM1 |
| striated muscle thin filament | cellular component | MYOM2, MYOM3, TTN, TMOD3, FHOD3, TMOD4, LMOD2, TMOD1, MYOM1, LMOD1 |
| subsarcolemmal mitochondrion | cellular component | PPARGC1A |
| succinate dehydrogenase complex | cellular component | SDHC |
| succinate-CoA ligase complex | cellular component | SUCLA2, SUCLG2 |
| succinate-CoA ligase complex (ADP-forming) | cellular component | SUCLG1 |
| succinate-CoA ligase complex (GDP-forming) | cellular component | SUCLG2 |
| SUMO activating enzyme complex | cellular component | UBA2, SAE1 |
| sumoylated E2 ligase complex | cellular component | UBE2I |
| supramolecular fiber | cellular component | SNCA, ODAM |
| supraspliceosomal complex | cellular component | RBMX, ADAR, UPF1 |
| sweet taste receptor complex | cellular component | TAS1R2, TAS1R3 |
| SWI/SNF complex | cellular component | RB1, SMARCA2, ACTL6A, BICRAL, SMARCA4, BRD9, SMARCE1, ARID1B, SS18, SMARCD3, NCR1, SMARCB1, SMARCC2, MYSM1, ARID1A, SMARCC1, SMARCD1, ACTL6B, BICRA, MPND |
| Swi5-Sfr1 complex | cellular component | SWI5, SFR1 |
| Swr1 complex | cellular component | SRCAP, DMAP1, RUVBL2, ING3, KAT5, ANP32E, RUVBL1, ZNHIT1, BRD8, ACTR6, EP400 |
| symbiont-containing vacuole | cellular component | RAB29, VTN, AQP1 |
| symbiont-containing vacuole membrane | cellular component | PF4, GBP2, AQP1 |
| symmetric synapse | cellular component | ARFGEF2, SLC4A8, NTSR1, CHRM2, PENK |
| symmetric, GABA-ergic, inhibitory synapse | cellular component | NLGN4X, NLGN2, NLGN4Y |
| synapse | cellular component | FMR1, MDM2, APP, ITGB1, ITGA5, CTNNB1, NSMF, INSR, NRG1, CALB2, SUMO1, PICK1, DNM1L, NF2, MYRIP, DSCAML1, LRRC4C, GOPC, PJA2, C1QB, GABRB1, RPL3, RPL5, RPS3A, FGF12, RPS7, RPS4X, RPL6, CAMK2B, PRRT2, GPC2, COPS5, RAB18, RAB21, PCDHB9, CHRNA5, RPL7A, RPS21, ASIC1, ADARB1, GRM4, ZNRF2, OLFM1, MAP1LC3A, ARL8B, RIMS2, ATP6AP2, PPT1, USP14, PPP2CA, RPL19, ANK3, RAPSN, ASIC2, KCNMB1, MFF, TANC2, GJD2, NPTN, ARHGAP32, SNAP23, SYNGR1, ADGRL1, UTS2, GNAI2, DMD, RPS9, GABRA2, GDI2, RPS20, PPP2R2A, CHRNE, GRIN1, HNRNPD, SYT13, NLGN4X, BAALC, PPP1R9B, RGS17, FZD4, MAPK8IP1, RAPGEF2, AP3B1, HTR3B, LGI1, CRYAB, RPS6KB1, SNCA, RPS19, HTR3A, RPS25, RPL38, PMP22, DPYSL3, CACNA1E, GRIPAP1, RIMS1, DLG5, TM9SF2, SH3GL2, LIN7C, PSD3, CORO1C, CACNG2, DVL1, MPDZ, NEURL1, RTN3, SNAPIN, AKR1A1, MPZ, HRH1, UTRN, GPM6A, FABP5, TPRG1L, GSG1L, TPGS1, ZDHHC17, RASD2, COPS4, TRIM9, SEMA4C, ARFGEF2, SLC4A7, TULP1, DLGAP1, CPLX1, PRKN, CTNND1, DTNB, PPFIA2, BCR, NRXN1, GNB1, ABR, ARID1B, MYCBPAP, DENND1A, SH3GL3, CBLN4, PGRMC1, LIN7A, SYNJ2, |
| synaptic cleft | cellular component | GRIN1, LGI1, DNM3, PRSS12, ADGRB3, CDH8, EGFLAM, LAMA5, CDHR3 |
| synaptic membrane | cellular component | ITGB1, FLRT3, SYNJ1, BAIAP2, NPTN, GRIN1, CRYAB, APH1A, ANXA1, LRRC1, SRPX2, DGKI, SCRIB, PSEN1, DLG1, AKAP9, GRIN2B, DLG4, NIPSNAP1, KCNK1, CDH8, PSEN2, GRIN2A, CSPG5, LRP4, PRKCG, ITGA3, GRIA1, TMEM240, HIP1R, OLFM2, NDUFS7, RIMS4 |
| synaptic vesicle | cellular component | VDAC2, KCNK9, ANXA5, VDAC1, ATP6V1B1, PRRT2, STX12, COPS5, RAB40A, SNCAIP, SEC22B, PPT1, SYPL1, MFF, SYNGR1, GRIN1, STX10, KIRREL3, VTI1B, GIPC1, SNAPIN, STX3, TPRG1L, APH1A, RAB3C, COPS4, TRIM9, RAB5A, NTF4, RAB8B, DISC1, VPS45, DDC, SYT1, RAB40B, PICALM, STXBP5, CTTNBP2, KIF1B, SNAP91, DGKI, SYP, DMXL2, SYN1, RAB15, IQSEC1, WDR7, STX7, VAMP4, RAB3B, AMPH, PSEN1, SYT12, BSN, SNAP25, SLC2A13, PDE4B, RAB11B, SV2C, CLCN3, RAB40C, VAMP7, SYPL2, APBA2, DNAJC5, SLC2A8, STON1, LAMP1, ATP6V0D1, DLG4, APBA1, CLN3, LGI3, SYN2, ROGDI, SLC40A1, SYNGR2, MT3, TMED9, TRAPPC4, TH, MME, SEPTIN1, VTI1A, SEPTIN5, RPH3A, HCRT, PSEN2, CLCN4, KIF1A, STX4, SLC4A8, SV2B, SLC30A3, STX11, NTF3, BACE1, RAB8A, GRIN2A, RAB3D, DNM1, SLC18A2, RABAC1, GRIA1, SYN3, SYT7, SYNGR3, SV2A, SYT2, BRSK1, SLC32A1, BIN1, STON2, RAB40AL, CLCN5, HAP1, LRRK2, SLC17A7, SLC6A17 |
| synaptic vesicle lumen | cellular component | PENK |
| synaptic vesicle membrane | cellular component | DNM1L, PRRT2, SYPL1, SYNGR1, SH3GL2, SNAPIN, TPRG1L, SEMA4C, MCTP2, SLC17A5, SYT1, VAMP1, BORCS5, SYT5, SYP, DMXL2, SYN1, DTNBP1, OTOF, AMPH, DOC2A, SYT12, BSN, SCAMP1, CALM3, MCTP1, SLC17A6, RAB11B, SV2C, SLC9B2, UNC13C, CLTA, PTPRN2, UNC13B, SNAP47, SYPL2, ICA1, PI4K2A, SYN2, SYNGR2, BCL2L1, TMEM163, CLTB, RPH3A, PTPRS, SYT6, SV2B, ZNRF1, SLC30A3, SYT9, SLC18A2, C16orf70, SYNGR4, DRD2, CBARP, SEPTIN8, UNC13A, SYN3, SYT7, SYNGR3, SV2A, SYT2, SLC32A1, GAD2, LRRK2, SLC17A7, SLC6A17 |
| synaptobrevin 2-SNAP-25-syntaxin-1a complex | cellular component | NAPA, NAPB |
| synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex | cellular component | CPLX1, SNAP25 |
| synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex | cellular component | CPLX2 |
| synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex | cellular component | CPLX1, CPLX2 |
| synaptonemal complex | cellular component | HSPA2, MSH5, REC8, MLH1, TEX11, MLH3, SYCE1, HORMAD1, HORMAD2, FKBP6, SYCP1, STAG3, SYCE1L, WAPL, UBE2I, SYN1, CCNB1IP1, PLK1, SYCP2, FAM9A, FAM9C, FAM9B, P3H4, INCENP, TEX12 |
| syntrophin complex | cellular component | DMD, SNTG2, SNTG1, SNTA1 |
| T cell receptor complex | cellular component | CD8A, SYK, STOML2, ZAP70, SKAP1, CD3E, CD3G, CD247, ALCAM, CD4, CEACAM1, CD6, CD8B, TRAT1 |
| T-tubule | cellular component | ESR1, TGFB3, EDNRA, CACNA2D1, EZR, CACNA1S, SRI, ANK3, NOS1AP, FXYD1, PPP3CB, RYR1, CAPN3, CACNA1C, SLC9A1, CAV3, SCN1B, ADRA1A, AHNAK, ATP1A2, ANK2, SCN2A, SLC30A1, SLC8A1, ASB3, RDX, SCN1A, SLC2A4, STBD1, ATP1B1, KCNJ2, ATP1A1, CACNG1, RTN2, DYSF, GOT2, AHNAK2, STAC3, CASQ1, SCN5A, BIN1, AKAP6 |
| t-UTP complex | cellular component | UTP4, HEATR1, NOL11 |
| TAP complex | cellular component | TAP1, TAP2 |
| TCR signalosome | cellular component | EZR, LCP2 |
| TEAD-1-YAP complex | cellular component | TEAD1, YAP1 |
| TEAD-2-YAP complex | cellular component | TEAD2, YAP1 |
| telomerase catalytic core complex | cellular component | TERT |
| telomerase holoenzyme complex | cellular component | TERT, TEP1, HNRNPU, DKC1, PTGES3, GNL3L, HNRNPC, LSM11, NOP10, NHP2, SNRPE, WRAP53, SNRPB, SMG7, SMG6, NVL, SMG5, NAT10, GAR1 |
| telomeric heterochromatin | cellular component | LRWD1 |
| terminal bouton | cellular component | ESR1, APP, POLG, CALB2, OXT, SYNJ1, PRNP, HSPA8, GRIN1, AP3D1, CPLX1, AP1S1, RAB5A, USH2A, SLC18A3, CALB1, SYP, BLVRB, NTRK2, NMU, PRSS12, AAK1, UNC13C, PTPRN2, UNC13B, GRIK3, GRIK5, CYFIP1, OPHN1, CALCA, ILK, TH, CCK, SLC4A8, KCNC2, P2RX4, CABP4, SLC18A2, CNGB1, NTSR1, P2RX3, UNC13A, CAD, GRIK2, TBC1D24, LRRK2, CPLX2, CPLX3 |
| terminal cisterna | cellular component | RYR1, RTN2, CASQ1 |
| terminal cisterna lumen | cellular component | CASQ1 |
| terminal web | cellular component | HFE, COBL, PLS1, KRT19, VCL |
| TERT-RMRP complex | cellular component | TERT |
| tertiary granule | cellular component | STX7, STXBP3, ADAM8, STXBP2 |
| tertiary granule lumen | cellular component | LTA4H, METTL7A, ARMC8, GOLGA7, CNN2, CSTB, CAMP, TNFAIP6, ILF2, ORM1, FTH1, PGM1, PTPN6, QSOX1, GGH, TCN1, DBNL, ALDOA, HBB, CANT1, CDA, CFP, YPEL5, OLFM4, CYFIP1, PRSS3, LRG1, CXCL1, QPCT, CTSS, SPTAN1, OSCAR, HP, FOLR3, PPBP, ALDOC, CTSH, GSDMD, MMP8 |
| tertiary granule membrane | cellular component | LAMTOR3, SLC2A3, ATP6AP2, RAP2B, OLR1, ATP8B4, SNAP23, COPB1, CD47, MGAM, CYBB, SERPINB6, PLD1, CD93, ANO6, VAMP8, CD59, CD53, TMEM63A, VAMP1, STOM, CLEC4C, ITGAM, CYBA, CEACAM8, UBR4, HGSNAT, MCEMP1, RAB14, CLEC12A, SNAP25, PTPRB, CYSTM1, SVIP, ATP11A, ITGAX, SLC11A1, STBD1, ITGB2, LAIR1, CEACAM1, CD33, FCAR, FPR2, FCER1G, TMC6, TSPAN14, CLEC5A, PTAFR, CLEC4D, GPR84, ADAM8, KCNAB2, LILRA3, ATP6V0C, NBEAL2, TRPM2, CHRNB4 |
| tetraspanin-enriched microdomain | cellular component | CD81, GP6, TSPAN9, SAMHD1, TSPAN15, PDPN, TSPAN14 |
| THO complex | cellular component | THOC7, THOC1, THOC2, THOC5, THOC6 |
| THO complex part of transcription export complex | cellular component | THOC3, THOC7, THOC1, THOC2, THOC5, THOC6 |
| tight junction | cellular component | TJP1, CLDN12, CLDN5, JAM3, F11R, EPHA2, CLDN1, JAM2, CLDN4, AFDN |
| TIM22 mitochondrial import inner membrane insertion complex | cellular component | TIMM10B, TIMM29, AGK |
| TIM23 mitochondrial import inner membrane translocase complex | cellular component | TIMM21, SLC25A6, TIMM50, TIMM17B, TIMM17A, TIMM10, PAM16 |
| Toll-like receptor 1-Toll-like receptor 2 protein complex | cellular component | TLR2, TLR1 |
| Toll-like receptor 2-Toll-like receptor 6 protein complex | cellular component | TLR6 |
| TORC1 complex | cellular component | MTOR, TTI1, LARP1, MLST8, AKT1S1, RPTOR |
| TORC2 complex | cellular component | MTOR, SESN3, PRR5L, MAPKAP1, TTI1, MLST8, PRR5, SESN2 |
| TRAF2-GSTP1 complex | cellular component | GSTP1, TRAF2 |
| TRAMP complex | cellular component | MTREX, ZCCHC8, TENT4B, TENT4A |
| trans-Golgi network | cellular component | IGF2R, CDH1, PAM, OPTN, DPY30, SCOC, RAB21, RAB11A, DOP1A, PHETA2, ARFGEF1, RAB29, RAB38, CCDC91, ARAP1, CNST, YIPF6, STX8, STX10, WLS, SLC24A5, LAP3, OCRL, PRKD1, PHETA1, GOLGA1, ARFGEF2, RGS20, RAB6A, PI4K2B, M6PR, RAB32, BICD1, ARF1, ATP2C1, SLC9A7, TBC1D23, LAMP2, ATP7B, DENND5A, POSTN, RAB30, TJAP1, GGA3, CBY1, VAMP4, RAB14, GOLT1A, MYO18A, SNX9, BACE2, SCAMP1, ATP9B, PCSK2, SNAP25, GOLGA4, PCSK4, ELAPOR1, ATP9A, FAM91A1, STX16, RAC1, VPS53, INPP5K, GOLPH3L, GOLPH3, ATP8A2, ATP11B, GSAP, ARL1, VAMP7, GCNT1, PREPL, ATG9A, ARL5B, C17orf75, KLHL20, TGOLN2, CLTCL1, ATP7A, TGFBI, AZIN2, PI4K2A, CHST6, BIRC6, RBFOX1, ATP11A, WIPI1, GCC2, PIFO, SORL1, VPS51, ATP8A1, SLC2A4, CLN3, CHST4, YIPF2, AP4M1, OSBP, GRN, CLVS1, PLEKHA8, SYT17, CHID1, GGA2, FUT9, AP4B1, PLOD3, CLASP2, MME, CLTB, FUT7, SLC66A2, PLEKHJ1, SMPD4, ARL5A, PLPP3, CORO7, STX4, GBF1, YIPF1, BACE1, ARFRP1, CHAC1, FURIN, EIPR1, C16orf70, NUCB1, NMNAT2, CHST5, CA4, PCSK7, MICALL1, DOP1B, CHST2, SLC10A7, CHST3, NBEA, TRAPPC9, MARCHF4, LRRK2, TRAPPC6B, |
| trans-Golgi network membrane | cellular component | HLA-DRB1, HLA-DPB1, GNAS, HLA-DQB1, HLA-DRA, APP, HLA-DQA1, IGF2R, RAB9A, USP6NL, CD74, RABEPK, VPS52, TMEM165, STX10, SLC24A5, TMEM79, AP1G1, AP1S2, BPNT2, RAB6A, AP1S1, PLD4, M6PR, RAB31, COG4, HLA-DQA2, ATP7B, AFTPH, CALN1, VAMP4, SCAMP1, LLGL1, VAMP3, AP1S3, STX16, RHOBTB3, CLTA, VPS53, GOLPH3L, MYO1B, HLA-DPA1, ARL1, NSG2, AP4S1, SCAMP2, ARFIP1, CLTC, COG8, BOK, RIC1, RGP1, VPS51, AP1B1, AP4M1, COG7, CLVS1, COG1, FUT9, AP4B1, MARCHF1, VTI1A, COG3, TEPSIN, RAB8A, ARFRP1, LGR5, NSG1, CABP7, SCAMP4, LGR6, BAIAP3, AP1M1, COG2, CLIP3, CLBA1, KIF13A, AP4E1 |
| trans-Golgi network transport vesicle | cellular component | IGF2R, GOPC, SPG21, RAB8B, RAB27B, RAB14, STEAP2, TGOLN2, TMED10, ATP7A, SORT1, SLC2A4, TMED9, RAB8A, FURIN |
| trans-Golgi network transport vesicle membrane | cellular component | NRGN, RASSF9 |
| transcription elongation factor complex | cellular component | CDK9, MLLT1, ZC3H8, ELP2, TTF2, ELL2, ICE2, ELL, ERCC6, ELP4, ELL3, AFF2, MLLT3, ICE1, NUFIP1, ELOF1, AFF3, TCEA2, AFF1, EAF2, EAF1 |
| transcription export complex 2 | cellular component | CETN2, ENY2, PCID2, MCM3AP, CETN3 |
| transcription factor AP-1 complex | cellular component | JUNB, FOS, JUND |
| transcription factor complex | cellular component | AHR, SOX9, HIF1A, HNF1B, E2F1, ARNT2, MTA2, PARP1, CTNNB1, RB1, PROP1, APEX1, SOX2, MEF2A, CLOCK, USF1, CREM, SIN3A, NPAS2, TP63, MED7, SKIL, RBL1, TCF7, RBL2, TFDP1, E2F5, KLF4, DDIT3, TLE1, E2F4, TBPL2, SPI1, PBX2, RFX5, IVNS1ABP, ATF1, RFX3, SMAD4, NCOA6, BEX1, TCF7L1, LHX3, SUB1, RIOX2, SOX18, PTOV1, ASCL3, HDAC9, HAX1, NFATC1, PBX3, PDLIM1, NAA16, HES6, AJUBA, SSBP3, SOX12, NFATC3, TAF7, E2F3, SKI, XRCC6, RELA, ZFHX3, DEAF1, ATF4, NFATC2, NR2E3, ETS1, NR4A2, LHX1, E2F2, MED23, SMAD6, SOX11, NHLH2, REL, MED25, SRA1, TAF1, YY1, PBX1, TLE4, EP300, KAT5, SIX3, PRKDC, TEAD2, ATF7IP, E2F6, TEAD1, RBPJ, RBM14, NAA15, WTIP, NFAT5, TCF4, JUNB, POU3F2, TFDP2, SNF8, DACH1, CREG1, YAP1, SOX4, KLF5, SMAD2, EPAS1, LEF1, SOX15, FOS, HCLS1, LMO2, PKNOX1, TLE2, NFATC4, SIX1, GFI1B, LDB1, E2F7, ALX4, SIX2, E2F8, MEIS1, GSC, POU4F2, RUNX2, DMBX1, SIX4, BARX2, RFXAP, LBX1, FOXF2, PMF1, HOXB13, LIMD1, ARNTL, YY2, MYOD1, MYOG, TLE5, FOXF1, TEAD4, WWTR1, SOX21, RFXANK, LDB2, SIX6, HOXA11, NR4A3, RARG, JUND, HOXA9, NKX2-5, DACH |
| transcription factor TFIIA complex | cellular component | GTF2A1L, TBPL1, GTF2A2, GTF2A1 |
| transcription factor TFIID complex | cellular component | TP53, ERCC1, TAF7L, TAF4B, GTF2H3, GTF2A2, TAF5, TAF12, TBPL2, TAF9B, GTF2F1, SUPT3H, GTF2B, TAF13, TAF7, TAF11, TAF3, TAF6L, TAF5L, TAF1, GTF2A1, TCEA1, TAF2, TAF6, TAF4, TAF10, GTF2H4, GTF2E2, GTF2E1, TAF9, GTF2H5 |
| transcription factor TFIIE complex | cellular component | GTF2E2, GTF2E1 |
| transcription factor TFIIF complex | cellular component | GTF2F1, GTF2F2 |
| transcription factor TFIIIB complex | cellular component | TBPL2, BDP1, BRF2, BRF1 |
| transcription factor TFIIIC complex | cellular component | GTF3C6, GTF3C3, GTF3C1, GTF3C2, GTF3C5, GTF3C4 |
| transcription factor TFIIK complex | cellular component | CDK7, CCNH, MNAT1 |
| transcription factor TFTC complex | cellular component | TADA3, TAF5, TAF12, TAF9B, SUPT3H, TAF7, TAF5L, TAF2, TAF6, TAF4, TAF10, KAT2A, TAF9 |
| transcription preinitiation complex | cellular component | GTF2H3, GTF2B, GTF2A1, GTF2F2, GTF2E1, ESR1 |
| transcriptional repressor complex | cellular component | ELANE, SIN3A, GLI3, HDAC4, SPEN, RBBP8, ZNF350, MIER1, RCOR3, DEPDC1, JAZF1, CCND1, CTBP2, SP3, REST, SKI, HDGF, INSM2, HMGB1, DDX20, N4BP2L2, RLIM, GPS2, ZNF224, INSM1, C1D, NCOR2, ETV3, RBPJ, RCOR1, CTBP1, LIN37, H1-0, YWHAB, HEY2, HDAC3, TBL1X, NCOR1, RCOR2, CDX2, PRDM10, CBX5, ZBTB16, AKIRIN2, PHF12, RELB, LIN9, GFI1, PRDM16, TFAP4, ZFPM1, CORO2A, GATA1 |
| transcriptionally active chromatin | cellular component | ESR1, EXOSC10, ZC3H8, WDR61, PSIP1, TTC37, ICE2, ELL, PAF1, PELP1, EXOSC5, CTR9, PADI2, H1-2, EXOSC3, ICE1, EXOSC4, H2AB1, KMT2E, BCAS3, H2AB2 |
| transferase complex | cellular component | PDSS2, UBE2I, PIAS4, PDSS1 |
| translation initiation ternary complex | cellular component | EIF2S1 |
| translation release factor complex | cellular component | GSPT1, ETF1, GSPT2 |
| transmembrane transporter complex | cellular component | CNGB3, CNGB1 |
| transport vesicle | cellular component | GNAS, FGFR3, IGF2R, MYRIP, IL33, USO1, ARCN1, RAB9A, NRSN1, RAB11A, SURF4, SEC22B, CD55, KDELR2, RABEPK, GOSR1, COPB2, COPB1, COPZ1, AP1AR, CNST, SYT13, APH1B, KDELR3, ANKRD27, COPE, CD59, AP3S1, M6PR, ATP13A2, NTS, AP1G2, DEFA5, TMED2, VAMP4, CPA3, CAV2, SCG3, PCSK2, BGN, TRIP11, NPTX1, VAMP3, GALNT15, COPG1, BET1, VAMP7, TMED7, SCAMP2, TGOLN2, TMED10, AZIN2, CHP1, COPA, ERG28, BLOC1S6, YIPF2, GOLIM4, PRG2, KDELR1, SSPN, SIPA1, TMED9, C1QTNF5, CRISPLD2, CPE, PCSK1, SFTA2, YIPF3, COPG2, PLIN3, EDN1, HCK, GOLGA5, NRSN2, YIPF1, VGF, OVGP1, TMEM187, YKT6, RAB3D, FGFR4, INS, ASTL, RAB1B, COPZ2, ARFGEF3, EXOC3L1, PLEKHF2, FOLR1 |
| transport vesicle membrane | cellular component | HLA-DRB1, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DQA1, PAM, AQP2, CD74, RAB11FIP5, RAB1A, ECE2, EEF1AKMT4-ECE2, SYTL4, SYT1, HLA-DQA2, CYB561, SYCN, SLC30A8, SCG3, TMEM30A, CLCN3, PTPRN2, RAB26, HLA-DPA1, VAMP7, TMED10, ICA1, MAP6, ITPR1, SORL1, SNTB2, CEACAM1, CPE, DBH, TMEM184A, SYT7, CA4, SYT3, RPH3AL, SYT10, ARFGEF3 |
| transverse filament | cellular component | SYCP1 |
| TRAPP complex | cellular component | TRAPPC12, TRAPPC3, TRAPPC11, TRAPPC3L, TRAPPC5, TRAPPC10, TRAPPC2L, TRAPPC2, TRAPPC2B, TRAPPC4, TRAPPC8, TRAPPC1, TRAPPC9, TRAPPC6B |
| TRAPPI protein complex | cellular component | TRAPPC5 |
| TRAPPII protein complex | cellular component | TRAPPC5, TRAPPC10 |
| TRAPPIII protein complex | cellular component | TRAPPC5, TRAPPC8 |
| TRC complex | cellular component | SGTA |
| tricarboxylic acid cycle enzyme complex | cellular component | FH |
| tricellular tight junction | cellular component | SIPA1L3, ILDR1, LSR |
| tRNA (m1A) methyltransferase complex | cellular component | TRMT61A, TRMT61B, TRMT6 |
| tRNA methyltransferase complex | cellular component | WDR4 |
| tRNA-intron endonuclease complex | cellular component | TSEN2, CLP1 |
| tRNA-specific adenosine-34 deaminase complex | cellular component | ADAT3 |
| tRNA-splicing ligase complex | cellular component | DDX1, RTRAF, RTCB, ZBTB8OS, FAM98A, FAM98B, C2orf49 |
| troponin complex | cellular component | TNNI2, TNNT1, TNNT3, TNNI1 |
| TSC1-TSC2 complex | cellular component | TSC1, TSC2 |
| tubular endosome | cellular component | VPS26A, SNX6, ANKRD27, SNX5, VPS35 |
| tubulobulbar complex | cellular component | ARPC1B |
| tumor necrosis factor receptor superfamily complex | cellular component | TRADD, TRAF2 |
| type III intermediate filament | cellular component | PRPH, UPP2 |
| U1 snRNP | cellular component | SNRPN, SNRNP70, LUC7L2, SNRPB2, SNRPC, LUC7L3, SNRPE, SNRPB, PRPF40A, SNRPD1, SNRPD2, LUC7L, SNRPG, RBMXL3, SNRPF, PRPF39, SNRPA |
| U11/U12 snRNP | cellular component | SF3B1 |
| U12-type spliceosomal complex | cellular component | SF3B1, SNRNP35, SNRNP25, PHF5A, ZCRB1, YBX1, SNRPE, SF3B2, DHX15, SNRPB, SNRPD1, SF3B6, SNRPD2, SNRPG, RNPC3, SNRNP48, SF3B3, SF3B4, ZRSR2, ZMAT5, SNRPF, LSM7 |
| U2 snRNP | cellular component | SNRPN, RBMX2, SF3B1, HTATSF1, SNRPB2, PHF5A, SNRPE, SF3B2, SNRPB, SNRPD1, SNRPD2, SNRPG, SNRPA1, SF3A1, SF3A3, SF3A2 |
| U2-type catalytic step 1 spliceosome | cellular component | RBM22, PRPF19, CWC25, CASC3, RBM8A, PRPF8, MAGOHB, ISY1, SNRNP200, YJU2, EIF4A3 |
| U2-type catalytic step 2 spliceosome | cellular component | PLRG1, CWC15, RBM22, PRPF19, SNRNP40, SRRM2, CDC40, SNRPB2, BUD31, SYF2, SNRPE, SNRPB, AQR, SNRPD1, SNRPD2, BCAS2, SNRPG, PRPF8, SNRPA1, SNW1, EFTUD2, PPIE, SNRPF, CDC5L, CRNKL1 |
| U2-type post-spliceosomal complex | cellular component | PRPF18 |
| U2-type precatalytic spliceosome | cellular component | IK, CWC27, LSM3, SF3B1, TXNL4A, MFAP1, SNIP1, SRRM2, SNRPB2, PRPF6, PHF5A, PRPF31, SNU13, SNRPE, SF3B2, PRPF38A, WBP4, SNRPB, SNRPD1, PRPF3, SNRPD2, SNRPG, SMU1, PRPF8, MAGOHB, SNRPA1, LSM6, SF3A1, SNRNP200, LSM8, SF3B3, SF3B4, EFTUD2, SF3A3, DHX16, SNRPF, LSM7, LSM2, SART1, SF3A2, LSM4, PRPF4 |
| U2-type prespliceosome | cellular component | SNRPN, SNRNP70, SF3B1, LUC7L2, SNRPC, LUC7L3, SNRPB, PRPF40A, LUC7L, SNRPG, SF3A1, RBMXL3, LSM7, U2AF2, PRPF39, SF3A2 |
| U2-type spliceosomal complex | cellular component | MFAP1, HTATSF1, CWC25, PRPF31, SF3B2, CCDC130, CCDC12, SF3A1, RNF113B |
| U2AF complex | cellular component | U2AF1L4, ZRSR2, U2AF1L5, U2AF1, U2AF2 |
| U4 snRNP | cellular component | SNRPN, DDX39B, PRPF31, SNRPE, SNRPB, SNRPD1, SNRPD2, SNRPG, SNRPF |
| U4/U6 x U5 tri-snRNP complex | cellular component | SNRPN, LSM3, TXNL4A, PRPF18, DDX23, PRPF6, SART3, PRPF31, SNU13, SNRPE, SNRPB, CD2BP2, SNRPD1, PRPF3, SNRPD2, SNRPG, PRPF8, USP39, LSM6, SNRNP200, LSM8, PPIH, EFTUD2, TXNL4B, SNRPF, LSM7, LSM2, SART1, LSM4, PRPF4 |
| U4atac snRNP | cellular component | PRPF31, SNU13 |
| U5 snRNP | cellular component | SNRPN, TXNL4A, SNRNP40, PRPF18, DDX23, PRPF6, SNRPE, SNRPB, CD2BP2, SNRPD1, SNRPD2, SNRPG, PRPF8, SNRNP200, TXNL4B |
| U6 snRNP | cellular component | LSM3, DDX39B, LSM6, LSM8, LSM7, LSM2, LSM4 |
| U7 snRNP | cellular component | LSM11, SNRPE, SNRPB, SNRPG, SNRPF |
| UBC13-MMS2 complex | cellular component | UBE2N, UBE2V2 |
| UBC13-UEV1A complex | cellular component | UBE2N, UBE2V1 |
| ubiquitin conjugating enzyme complex | cellular component | STUB1, UBE2V1 |
| ubiquitin ligase complex | cellular component | BRCA1, UBR2, HSPA1A, HSPA1B, RNF8, MED7, UBE2D3, RNF20, FEM1C, UBE4A, FBXO11, ASB12, DCUN1D1, BRAP, RNF168, DCUN1D4, RNF19A, FBXL5, ARMC8, FBXO8, FBXL12, RNF14, ARIH1, UBE2N, RNF144B, WDR26, FBXO9, ARIH2, SUGT1, PRKN, RNF217, ANKIB1, MAEA, DCUN1D5, RMND5A, FBXO4, STUB1, MED21, MED10, CBX8, FBXO10, FBXL4, UBE2D4, GID4, NEDD4, UBR1, DYRK2, MED31, FBXO24, UBR3, FBXL3, IKBKG, BMI1, UBE2L3, UBE2V1, FBXO25, SHARPIN, TRAF7, CAND1, RNF11, WWP2, YPEL5, RNF19B, RCHY1, RBCK1, WWP1, GID8, RNF40, CBLL1, UBE2J2, MED30, UBE2L6, UBE2D1, UBE2E1, UBE4B, BARD1, MED12, RNF144A, UBE2C, RING1, SMURF2, FBXO7, FEM1A, FBXO21, MIB2, FBXL7, TRAF2, MED27, DCUN1D2, RANBP10, ABTB1, TOPORS, AMFR, UBE3D, RNF2, ASB1 |
| UDP-N-acetylglucosamine transferase complex | cellular component | ALG14, EXT2, UGT3A1 |
| UFD1-NPL4 complex | cellular component | UFD1, NPLOC4 |
| unconventional myosin complex | cellular component | MYL6, MYO5A, MYO6, MYO9A, MYO1F, MYL6B, MYO18B, MYO1C |
| uniplex complex | cellular component | SMDT1, MICU2, MCUB, MICU1 |
| upper tip-link density | cellular component | MYO7A |
| uropod | cellular component | EZR, PSTPIP1, FLOT1, PIP5K1B, MSN, SELPLG, BST1, SPN, MYH9, PIP5K1C |
| USH2 complex | cellular component | USH2A, ADGRV1, WHRN, PDZD7 |
| UTP-C complex | cellular component | RRP7A, NOL6 |
| vacuolar membrane | cellular component | ARL8B, SLC36A4, CTNS, SLC36A1, THBD, SLC30A2, ATP6V1A, SLC3A1, ABCC11, SLC36A2, SLC36A3, SBF2, ARL8A, YWHAB, VAC14, NAPA, SLC22A17, ATP6V0B, ABCB6, TMEM138, ATP6V0C, MAN2B2, NAPB, VMP1, NAPG |
| vacuolar proton-transporting V-type ATPase complex | cellular component | ATP6V0A2, ATP6V1B1, ATP6V1G1, ATP6AP2, ATP6V1G2, TMEM199, ATP6V1G3, CCDC115, ATP6V0D1, ATP6V0A4, ATP6V1F, TCIRG1, ATP6V0A1 |
| vacuolar proton-transporting V-type ATPase, V0 domain | cellular component | ATP6V0A2, ATP6V0A4, TCIRG1, ATP6V0A1 |
| vacuolar proton-transporting V-type ATPase, V1 domain | cellular component | ATP6V1C1, ATP6V1H, ATP6V1C2 |
| vacuole | cellular component | GLB1, RAB29, CD74, VMA21, CTSV, STX3, TMEM208, SLC30A2, GGH, ABCC11, YWHAB, LAMP1, CLN3, SLC22A17, ATP6V0B, GLB1L3, MST1R, STX4, GLB1L, TMEM138, ATP6V0C, CPA2, VMP1, GLB1L2 |
| varicosity | cellular component | TNFRSF1B, CRH, CRHBP, UCN, UCN3, DNM1, CD40, DAGLA, MAP1B |
| VCB complex | cellular component | USP33, ELOB, CUL2, RBX1, VHL |
| VCP-NPL4-UFD1 AAA ATPase complex | cellular component | FAF2, UFD1, UBXN7, FAF1, RNF125, NPLOC4, UBXN1 |
| VCP-NSFL1C complex | cellular component | NSFL1C |
| very-low-density lipoprotein particle | cellular component | APOE, APOB, SELENOS, PCYOX1, LPL, LSR, VLDLR, APOO, APOA1, APOC1, APOA5, APOC3, APOM, APOL1, APOH, APOBR |
| vesicle | cellular component | IL1B, IL1RN, AKT1, CIB1, TF, GAPDH, GSTP1, MIF, MUC1, SLC6A14, EZR, ANXA2, PACRG, MUC16, KIF5B, PRRT2, STX12, VPS26A, SRI, RAB11A, PIK3C2A, RAB29, ANXA7, RAB38, MYL6, ALS2, GDI2, STX8, STX10, ECE1, CD81, RPS27A, STX5, MYO5C, VTI1B, CORO1C, LAMP3, DYNC1I1, SLC9A3R1, SPP1, RAB4A, DYNC1I2, RAB3C, VAMP8, KCNN4, ANXA1, F7, CD59, NRXN1, SLC47A1, PKM, RAB32, CHMP4B, ATP13A2, STOM, PICALM, NOD2, MYO5A, TSPAN4, ANXA9, YWHAZ, TKT, CAV3, STX7, BMP1, RAB3B, AHNAK, CAPS, GLT6D1, VAPA, MYO6, TSPAN1, CALM1, CALM2, CALM3, SNAP25, BMP5, EPS8, TBC1D4, MSN, PLN, BASP1, RIPK2, MYO1B, SERPINB3, ARHGEF2, UBC, LRPAP1, OPRD1, PRKCZ, DCTN2, SLC30A7, MYO5B, NPC1, NPFF, UBA52, GPRC5A, MUC4, TUBA1C, KIF9, CLIC1, GAK, DNAJC6, LAMP1, SLC2A4, BMP6, APPL2, MYO1F, TAGLN2, YWHAG, MVB12A, LZTS2, WDR54, CASK, ALDH3B1, GNB2, H1-1, GIGYF2, SLC34A3, WDFY2, GPRC5C, MYO1C, CSH1, KCNC2, RAB34, RAB3D, UBB, CETP, ABO, LIM2, LGR6, MYO7A, CLEC16A, MYO7B, MYO1G, SLC34A1, SLC26A6, MVB12B, MYO1D, CSH2, PPIA, SPRN, KCNE3, HSPA1A, HSPA1B, Grn |
| vesicle coat | cellular component | SEC31A, SEC31B |
| vesicle lumen | cellular component | APOB |
| vesicle membrane | cellular component | APOB, ACPP, ANXA4, SYNJ1, ATP2A2, RAB21, SLC28A2, PIKFYVE, NCK1, GIPC1, ATP13A2, NCK2, GAD1, GBP1, CLCN3, GRB2, STK26, SLC2A4, SLC4A11, SLC5A6, WAS, APPL1, DGKQ, TRAF2, BAIAP2L2, SLC26A6, ASPSCR1, RIPOR1, FNDC3A |
| vesicle tethering complex | cellular component | SYNPO2 |
| viral envelope | cellular component | env, ERVW-1, ERVFRD-1 |
| viral integration complex | cellular component | TOP2A, TOP2B |
| viral replication complex | cellular component | FMR1, SHFL, MOV10, PI4KA |
| virion | cellular component | env, ERVW-1, ERVFRD-1 |
| virion membrane | cellular component | env |
| voltage-gated calcium channel complex | cellular component | CACNA2D1, CACNA1S, CACNA1E, CACNG2, CACNG6, CACNA1C, CACNG3, CACNG7, CACNA2D2, CACNA1A, PDE4B, CACHD1, CACNA1G, PDE4D, CACNA1I, CACNG4, CACNB4, CACNA1H, CACNA1D, CACNB1, CACNG1, CACNB3, STAC3, CACNA1B, CACNA2D4, CACNA2D3, CACNB2, CACNG8 |
| voltage-gated potassium channel complex | cellular component | DPP6, SUMO1, KCNAB1, KCNMB1, KCNJ16, KCNK2, KCNMB3, LRRC26, KCNH4, KCNA4, KCNH2, KCNN1, KCND3, KCNN4, CTTN, KCND2, KCNIP4, KCND1, KCNQ3, KCNG1, KCNQ2, KCNG4, CNTNAP2, CALM3, SNAP25, KCNC4, LRRC52, KCNB1, AKAP9, KCNE4, KCNJ4, DLG4, KCNV1, KCNF1, HCN2, KCNA6, KCNJ2, KCNV2, KCNS3, KCNIP1, KCNG2, KCNK1, KCNAB3, KCNE1, KCNA2, KCNIP2, KCNC1, KCNQ4, KCNJ8, KCNC2, KCNAB2, KCNA3, KCNA1, AMIGO1, KCNIP3, KCNJ1, KCNMA1, KCNC3, DLG2, KCNMB4, KCNG3, LRRC55, KCNQ5, KCNK6, KCNE3 |
| voltage-gated sodium channel complex | cellular component | SCN11A, SCN1B, SCN2A, CACNA1G, SCN1A, CACNA1I, CACNA1H, SCN4A, SCN4B, SCN5A, SCN10A, SCN2B, SCN3B, SCN8A |
| WASH complex | cellular component | WASHC5, SNX27, WASHC2A, WASHC3, CAPZA1, WASHC4, TBC1D23, CAPZB, WASHC2C |
| Weibel-Palade body | cellular component | VWF, RAB27A, ECE1, UNC13D, EDN1 |
| Wnt signalosome | cellular component | GSK3B, CTNNB1, ADGRA2, DVL1, LRP6, APC, LRP5, WNT3, FZD1, RECK, LRRK2 |
| Wnt-Frizzled-LRP5/6 complex | cellular component | FZD8, WNT3A, LRP6, LRP5 |
| XPC complex | cellular component | RAD23B, XPC, CETN2 |
| XY body | cellular component | UBE2B, H2AFX, SUMO1, MAEL, Dmrtc2, SIN3B, BIRC2, SMARCC1, PBX4 |
| Y chromosome | cellular component | SIN3B |
| Z disc | cellular component | MYH7, HSPB1, CTNNB1, AKAP4, ANK1, ANXA5, HDAC4, CAB39, DES, SRI, PPP2R5A, PALLD, PPP1R12A, TCAP, MYOM2, ANK3, DMD, FRG1, FBXL22, MYL12B, CRYAB, NEB, NOS1AP, FLNB, NEXN, CASQ2, PPP3CB, RYR1, RYR2, PDLIM1, BAG3, CAPN3, CACNA1C, SYNPO, PDLIM2, STUB1, CFL2, GLRX3, MYOM3, FBXO32, ACTN2, CAV3, DST, FLNC, NRAP, TTN, ADRA1A, PSEN1, FHL2, FHL5, MYPN, PGM5, JPH2, SORBS2, ANK2, PDE4B, SYNPO2, NEBL, ACTN1, CSRP3, PPP3CA, FBXO22, XIRP2, KRT19, SLC8A1, OBSCN, OBSL1, CSRP1, FKBP1B, SMN1, PARVB, SCN1A, HOMER1, PDLIM5, PARVA, LDB3, PDLIM7, FBP2, PPP1R12B, KRT8, JUP, KCNE1, PSEN2, PDLIM4, PDLIM3, MYO18B, SYNE2, TRIM54, SYNC, HRC, CACNA1D, FHOD3, AHNAK2, JPH1, ITGB1BP2, MYH6, ACTN4, SLC4A1, CASQ1, MYOM1, SCN5A, CEFIP, BIN1, KY, KCNN2, MYZAP, MYOZ1, MYOZ2, SCN3B, SCN8A, S100A1 |
| zeta DNA polymerase complex | cellular component | REV3L, POLD2, MAD2L2 |
| zona pellucida receptor complex | cellular component | HSPA1L, CCT4, CCT2, TCP1, CCT3, CCT8, ZPBP2 |
| zonula adherens | cellular component | SORBS1, CTNNA1, CTNND1, KIFC3, VCL, JUP, CAMSAP3 |
| zymogen granule | cellular component | GNAI3, RAB3D |
| zymogen granule membrane | cellular component | STX3, RAB27B, DMBT1, TMED2, SCAMP1, TMED10, STXBP2 |
| A axonemal microtubule | colocalizes with | CFAP206 |
| amyloid-beta complex | colocalizes with | ROCK1 |
| AP-3 adaptor complex | colocalizes with | VPS41, VPS18, AP3B1, AP3S2, AP3D1, AP3S1, AP3B2, VPS33A, VPS39 |
| basal ectoplasmic specialization | colocalizes with | KIAA1210 |
| calcium channel complex | colocalizes with | SESTD1, CASQ2, RYR1, RYR2, PKD2L1, CALM1, CALM2, CALM3, MICU2, FKBP1B, PDE4D, ASPH, MCUB, TRPC5, TRPC4, MICU1, ATP2A1, AKAP6 |
| chromaffin granule membrane | colocalizes with | SRI, ANXA7, SYT1, DNAJC5, ATP8A1, DBH, SYT2 |
| clathrin complex | colocalizes with | VPS41, SCLT1, CLTA, CLTCL1, CLTC, VPS33A, BAIAP2L2, SCN10A |
| contractile ring | colocalizes with | UTRN, PRC1, KIF20B, ALKBH4, DAG1, PDXP |
| cortical endoplasmic reticulum | colocalizes with | EMD, ARV1, OSBPL8, STIMATE, ASPH, C2CD2L, TMEM201, STIM1 |
| cortical microtubule plus-end | colocalizes with | PDE4DIP, CLASP2 |
| Cul5-RING ubiquitin ligase complex | colocalizes with | ARIH2, CUL5, ELOB, RBX1 |
| cytoplasmic region | colocalizes with | ITGB2 |
| cytosolic small ribosomal subunit | colocalizes with | EIF2D, RPS10, RPS3A, RPS7, RPS14, RPS4X, RPS6, MCTS1, DDX3X, RPS8, RPS21, RPS18, RPS13, RPS9, RPS20, RPS23, RPS27L, EIF2A, RPS2, RPS19, RPS5, RPS25, RPS27A, RACK1, RPS3, RPS12, RPS27, RPS4Y1, DHX29, RPS16, RPS29, RPS15, RPS15A, RPS24, RPS28, RPS17, UBA52, RPSA, RPS11, HBA1, RPS4Y2 |
| Dcp1-Dcp2 complex | colocalizes with | ZFP36 |
| DNA-dependent protein kinase complex | colocalizes with | UVRAG, ZBTB7A |
| GATOR2 complex | colocalizes with | SESN3, SEC13, MIOS, CASTOR3, SEH1L, SZT2, SESN2, WDR24, WDR59 |
| Holliday junction resolvase complex | colocalizes with | RAD51C, SLX4, MUS81, EME2 |
| IkappaB kinase complex | colocalizes with | MAP3K7, TRIM40, PYDC1, ERC1, IKBKG, IKBKB, PYCARD |
| inward rectifier potassium channel complex | colocalizes with | NOS1AP, KCNH2, KCNK1 |
| ionotropic glutamate receptor complex | colocalizes with | LRRC1, SCRIB, SHANK2, DLG1, GRIK5, DLG4, DLG3, GRID2, GRIA1, SHANK1, GRIK2, DLG2, SYNJ2BP |
| LUBAC complex | colocalizes with | OTULIN, SHARPIN, RBCK1, RNF31 |
| membrane microdomain | colocalizes with | LAMP2, PTPRC, DYSF |
| MICOS complex | colocalizes with | DNAJC11, CHCHD6, APOO, IMMT, MICOS10, MICOS13, CHCHD3, CHCHD10 |
| microtubule bundle | colocalizes with | TPPP3, MARK2, NUMA1, MTCL1, TPPP |
| microtubule minus-end | colocalizes with | ABRAXAS2, CAMSAP1, CAMSAP2, SVIL, NIN, ASPM, NUMA1, CAMSAP3 |
| mitochondrion-derived vesicle | colocalizes with | PRKN, VPS35 |
| mitotic spindle pole | colocalizes with | IK, BCCIP, GPSM2, NIN, KATNA1, SMC3, TNKS, CDK5RAP2, FAM83D, ASPM, RAE1, KATNBL1, KIF20B, STAG2, STAG1, MAD1L1, YPEL5, NUMA1, FAM161A, MAPKBP1, SMC1A, OR2A4, EML1 |
| neurofilament | colocalizes with | DYRK1A, NEFH, SHANK2, NEFM, NRP1, INA, NEFL |
| radial spoke stalk | colocalizes with | CFAP91, CFAP61 |
| Ragulator complex | colocalizes with | SLC38A9, LAMTOR3, LAMTOR5, LAMTOR1 |
| retromer complex | colocalizes with | SNX3, VPS26A, VPS29, MAGEL2, SNX6, SNX2, SNX27, ENTR1, VPS26B, SNX8, ANKFY1, DENND5A, SNX5, RAB7A, DENND4C, SNX12, TBC1D5, VPS35 |
| RNA N6-methyladenosine methyltransferase complex | colocalizes with | VIRMA, RBM15, WTAP, ZC3H13, CBLL1, RBM15B |
| SAM complex | colocalizes with | DNAJC11, SAMM50, MTX2, CHCHD6, APOO, MTX3, IMMT, MICOS10, MTX1, MICOS13, CHCHD3 |
| transcription export complex | colocalizes with | ZC3H11A, C12orf50, SARNP, THOC3, DDX39B, THOC7, THOC1, ALYREF, THOC2, CHTOP, THOC5, NXF1, THOC6 |
| tubulin complex | colocalizes with | BICD1 |
| U2-type post-mRNA release spliceosomal complex | colocalizes with | DHX15, TFIP11 |
| U4/U6 snRNP | colocalizes with | SART3, PPIH, PRPF4 |
| U6atac snRNP | colocalizes with | SART3 |
| X chromosome | colocalizes with | PCGF3, PCGF5, SIN3B |
| 3' overhang single-stranded DNA endodeoxyribonuclease activity | contributes to | ERCC4 |
| 3'-flap endonuclease activity | contributes to | SLX4, MUS81 |
| A-type (transient outward) potassium channel activity | contributes to | KCND3, KCND2, KCND1, KCNIP2 |
| acetylcholine binding | contributes to | CHRNA5, CHRNE, CHRNA2, CHRNB1, CHRM3, CHRNA7, CHRND, CHRFAM7A, CHRNA3, CHRNA6, CHRNG, CHRNB2, CHRNA4, CHRNA1, CHRNB4 |
| activin-activated receptor activity | contributes to | ACVR1B, ACVR2B, ACVR2A, TGFBR2 |
| alpha-ketoacid dehydrogenase activity | contributes to | BCKDHB, BCKDHA |
| AMPA glutamate receptor activity | contributes to | GRIA2, GRIA3, GRIA1 |
| amylin receptor activity | contributes to | RAMP2, RAMP3, RAMP1, CALCR |
| ATP-dependent peptidase activity | contributes to | CLPX, CLPP, LONP2, YME1L1, LONP1 |
| CAAX-protein geranylgeranyltransferase activity | contributes to | FNTA, PGGT1B |
| cytoskeletal protein-membrane anchor activity | contributes to | ACTR10, EPB41L3, ACTR1A, JUP, ACTR1B, SPTBN4 |
| DNA clamp loader activity | contributes to | RFC4, RFC5, RFC3, DSCC1, RAD17, CHTF8, RFC2, CHTF18, RFC1 |
| dolichyl-diphosphooligosaccharide-protein glycotransferase activity | contributes to | RPN2, STT3B, RPN1, STT3A, OSTC |
| GABA receptor activity | contributes to | GABRB2, GABRA1 |
| GPI anchor binding | contributes to | GPAA1, THY1, PIGK, PIGU, DPEP1 |
| H3K27me3 modified histone binding | contributes to | TAF7, CHD5, TAF1 |
| haptoglobin binding | contributes to | HBG2, HBD, HBB, HBZ, HBQ1, HBA1 |
| histone acetyltransferase activity (H3-K23 specific) | contributes to | BRPF1, MEAF6 |
| histone acetyltransferase activity (H4-K16 specific) | contributes to | OGT, KANSL1L, WDR5, MSL3, KANSL2, KANSL1, PHF20, KANSL3, MCRS1 |
| histone acetyltransferase activity (H4-K5 specific) | contributes to | OGT, KANSL1L, WDR5, KANSL2, KANSL1, PHF20, KANSL3, MCRS1 |
| histone acetyltransferase activity (H4-K8 specific) | contributes to | OGT, KANSL1L, WDR5, KANSL2, KANSL1, PHF20, KANSL3, MCRS1 |
| interleukin-12 receptor activity | contributes to | IL12RB1 |
| interleukin-23 binding | contributes to | IL12RB1, IL23R |
| interleukin-23 receptor activity | contributes to | IL12RB1, IL23R |
| interleukin-3 receptor activity | contributes to | CSF2RB |
| interleukin-4 receptor activity | contributes to | IL2RG, IL4R |
| interleukin-5 receptor activity | contributes to | CSF2RB, IL5RA |
| methylcrotonoyl-CoA carboxylase activity | contributes to | MCCC1, MCCC2 |
| nucleosome binding | contributes to | EED, SUPT16H, RNF168, SMARCA5, NAP1L4, ARID1B, GLYR1, SAP30L, L3MBTL1, DNTTIP1, HP1BP3, SMARCA1, MLLT10, RNF169, ZNHIT1, ARID1A, ACTR6, RCC1, MLLT6, SSRP1, PWWP3A, NOC2L |
| nucleosome-dependent ATPase activity | contributes to | SMARCA1, CHD3 |
| phosphatidic acid transfer activity | contributes to | PRELID1, PRELID2, PRELID3A, TRIAP1, PRELID3B |
| poly(A)-specific ribonuclease activity | contributes to | PAN3, CNOT1, CNOT8, PARN, TOE1, PAN2, CNOT6L, CNOT2, CNOT3 |
| protein farnesyltransferase activity | contributes to | FNTA, FNTB |
| queuine tRNA-ribosyltransferase activity | contributes to | QTRT2, QTRT1 |
| ribonuclease MRP activity | contributes to | POP4, POP1 |
| ribonuclease P activity | contributes to | POP4, RPP14, RPP38, POP1, RPP25, PRORP, POP5, RPP21, POP7 |
| RNA polymerase I activity | contributes to | POLR1C, POLR1A |
| RNA polymerase III activity | contributes to | POLR1C |
| single-stranded 3'-5' DNA helicase activity | contributes to | MCM7, MCM6 |
| single-stranded DNA helicase activity | contributes to | RFC4, RFC5, RFC3, DSCC1, CHTF8, WRNIP1, RFC2, HELB, CHTF18, RAD18 |
| stretch-activated, cation-selective, calcium channel activity | contributes to | FAM155B, FAM155A |
| sweet taste receptor activity | contributes to | TAS1R2, TAS1R3 |
| trans-hexaprenyltranstransferase activity | contributes to | PDSS2, PDSS1 |
| translation initiation factor activity | contributes to | EIF3H, DENR, EIF2D, EIF3E, COPS5, MCTS1, EIF1AY, EIF3D, EIF4G2, EIF3K, EIF3L, EIF3F, EIF2S2, EIF4A2, EIF3M, EIF1, EIF2A, EIF3G, EIF3J, EIF2S3, EIF2B3, EIF3A, EIF2B1, EIF4A1, EIF1AD, EIF3B, EIF5, DHX29, MTIF3, EIF4E, EIF3C, EIF4E2, EIF5B, EIF4B, EIF2S1, AGO2, EIF4E3, EIF1B, EIF1AX, EIF2B2, EIF6, EIF2B5, EIF3I, EIF2B4, EIF4H |
| tRNA (guanine-N7-)-methyltransferase activity | contributes to | WDR4 |
| plasma membrane protein complex | is active in | SLC6A6, SLC9A3R1, HJV, EFCAB7, HSPG2, LRP1, RET, EVC, EVC2 |
| (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity | molecular function | FASN |
| (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity | molecular function | ST6GALNAC4, ST6GALNAC3 |
| (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity | molecular function | B4GALNT1 |
| (R)-2-hydroxyglutarate dehydrogenase activity | molecular function | IDH1, D2HGDH |
| (R)-limonene 6-monooxygenase activity | molecular function | CYP2C19, CYP2C9 |
| (R,R)-butanediol dehydrogenase activity | molecular function | SORD |
| (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity | molecular function | ADSL |
| (S)-2-hydroxy-acid oxidase activity | molecular function | HAO2, L2HGDH, HAO1 |
| (S)-3-amino-2-methylpropionate transaminase activity | molecular function | ABAT |
| (S)-citramalyl-CoA lyase activity | molecular function | CLYBL |
| (S)-limonene 6-monooxygenase activity | molecular function | CYP2C19, CYP2C9 |
| (S)-limonene 7-monooxygenase activity | molecular function | CYP2C19, CYP2C9 |
| 1,4-alpha-glucan branching enzyme activity | molecular function | GBE1 |
| 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) | molecular function | GBE1 |
| 1,4-alpha-oligoglucan phosphorylase activity | molecular function | PYGL, PYGB, TYMP, MTAP, PYGM |
| 1,5-anhydro-D-fructose reductase activity | molecular function | AKR1E2 |
| 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding | molecular function | HTR2C |
| 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity | molecular function | PNLIPRP2 |
| 1-acyl-2-lysophosphatidylserine acylhydrolase activity | molecular function | PLAAT1, LPL, PLAAT3, LIPG, PLAAT5, LIPC, PLA2G15 |
| 1-acylglycerol-3-phosphate O-acyltransferase activity | molecular function | LCLAT1, MBOAT2, AGPAT1, ABHD5, AGPAT2, AGPAT3, PNPLA3, AGPAT4, GPAT3, LPCAT2, LPCAT1, CRLS1, MBOAT7 |
| 1-acylglycerophosphocholine O-acyltransferase activity | molecular function | LPCAT2, LPCAT1, LPCAT3, LPCAT4 |
| 1-alkenylglycerophosphocholine O-acyltransferase activity | molecular function | LPCAT2, LPCAT1 |
| 1-alkenylglycerophosphoethanolamine O-acyltransferase activity | molecular function | LPCAT4 |
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | molecular function | PAFAH1B2, PAFAH2, PLA2G10, PLA2G7, PAFAH1B3, ASPG, LCAT |
| 1-alkylglycerophosphocholine O-acetyltransferase activity | molecular function | LPCAT2, LPCAT1, LPCAT4 |
| 1-alkylglycerophosphocholine O-acyltransferase activity | molecular function | LPCAT1 |
| 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity | molecular function | CYP24A1 |
| 1-ethyladenine demethylase activity | molecular function | ALKBH1 |
| 1-phosphatidylinositol 4-kinase activity | molecular function | PI4K2B, PI4K2A, PI4KB, PI4KA |
| 1-phosphatidylinositol binding | molecular function | SCIN, WDFY1, SESTD1, SNX10, ZFYVE16, SCARB1, PICALM, ZFYVE1, SNAP91, SNX9, EEA1, WDFY3, EPB41, FRMPD2, ZFYVE9 |
| 1-phosphatidylinositol-3-kinase activity | molecular function | FGFR2, FGFR3, ATM, FGFR1, PIK3CA, FGF17, FGF8, PTPN11, FGF3, FGF9, PIK3C2A, PIK3C3, PIK3R3, PIK3CG, PIK3C2B, PIK3CD |
| 1-phosphatidylinositol-3-kinase regulator activity | molecular function | CISH, SOCS2, PIK3R1, SOCS5, SOCS4, SOCS1, SLA2, PIK3R3, SOCS7, SOCS6, PIK3R2, PIK3R6, PIK3R5, SOCS3 |
| 1-phosphatidylinositol-3-phosphate 5-kinase activity | molecular function | PIKFYVE |
| 1-phosphatidylinositol-4-phosphate 3-kinase activity | molecular function | PIK3CA, PIK3C2A, PIK3CG, PIK3C2B, PIK3CD |
| 1-phosphatidylinositol-4-phosphate 5-kinase activity | molecular function | PIKFYVE, PIP5K1A, PIP4K2A, PIP5K1B, PIP4K2B, PIP5K1C |
| 1-phosphatidylinositol-5-phosphate 4-kinase activity | molecular function | PIP4K2A, PIP4K2C, PIP4K2B |
| 1-pyrroline dehydrogenase activity | molecular function | ALDH9A1 |
| 1-pyrroline-5-carboxylate dehydrogenase activity | molecular function | ALDH4A1 |
| 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity | molecular function | EPHX2 |
| 11-beta-hydroxysteroid dehydrogenase (NADP+) activity | molecular function | HSD11B1 |
| 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity | molecular function | HSD11B1, HSD11B2 |
| 11-cis retinal binding | molecular function | OPN5, RLBP1, RHO, OPN4 |
| 12-hydroxyheptadecatrienoic acid synthase activity | molecular function | TBXAS1 |
| 13-prostaglandin reductase activity | molecular function | PTGR1, ZADH2, PTGR2 |
| 14-3-3 protein binding | molecular function | AKT1, BAD, YWHAQ, PPP1R12A, NEK1, DAB2IP, KLHL22, SRPK2, TBC1D22B, IRS2, SYNPO2, KSR1, TBC1D22A, TMCC3, HDAC7, PRKCZ, ZFP36, ZFP36L1, RBM7, PRKCE, KIF13B, PI4KB, ARRB2, SIK1, FOXK1, AANAT, RPTOR, HLA-F, RIPOR1, RIPOR2 |
| 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | molecular function | HPGD, CBR1, ABCC4 |
| 15-hydroxyprostaglandin dehydrogenase (NADP+) activity | molecular function | CBR1 |
| 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity | molecular function | AKR1C3 |
| 15-oxoprostaglandin 13-oxidase activity | molecular function | PTGR1, ZADH2, PTGR2 |
| 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity | molecular function | HSD17B2, AKR1C1 |
| 17-alpha-hydroxyprogesterone aldolase activity | molecular function | CYP17A1 |
| 17-beta-hydroxysteroid dehydrogenase (NAD+) activity | molecular function | HSD17B4 |
| 17-beta-hydroxysteroid dehydrogenase (NADP+) activity | molecular function | DHRS11 |
| 17-beta-ketosteroid reductase activity | molecular function | DHRS11 |
| 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity | molecular function | DIMT1 |
| 2 iron, 2 sulfur cluster binding | molecular function | XDH, SDHB, GLRX5, ISCA2, UQCRFS1, FXN, ISCA1, FECH, CIAPIN1, GLRX2, FDX1, NDUFS1, NDUFV2, ISCU, CISD1, FDX2, RFESD, AOX1, AIFM3, CISD3 |
| 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity | molecular function | ADPRM |
| 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity | molecular function | CNP |
| 2'-5'-oligoadenylate synthetase activity | molecular function | OAS1, OASL, OAS2 |
| 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity | molecular function | PGAM1, PGAM4, PGAM2 |
| 2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity | molecular function | ENOPH1 |
| 2,4-dienoyl-CoA reductase (NADPH) activity | molecular function | DECR1, DECR2, PECR |
| 2-(3-amino-3-carboxypropyl)histidine synthase activity | molecular function | DPH2 |
| 2-acylglycerol O-acyltransferase activity | molecular function | MOGAT1, DGAT2, DGAT1, MOGAT2, MOGAT3 |
| 2-acylglycerol-3-phosphate O-acyltransferase activity | molecular function | CRLS1, MBOAT7 |
| 2-alkenal reductase [NAD(P)+] activity | molecular function | PTGR1 |
| 2-aminoadipate transaminase activity | molecular function | AADAT |
| 2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | molecular function | COQ5 |
| 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity | molecular function | ENOPH1 |
| 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity | molecular function | UGT8 |
| 2-hydroxyglutarate dehydrogenase activity | molecular function | L2HGDH |
| 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity | molecular function | COQ5 |
| 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity | molecular function | COQ7 |
| 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity | molecular function | COQ3 |
| 23S rRNA (adenine(1618)-N(6))-methyltransferase activity | molecular function | METTL16 |
| 25-hydroxycholecalciferol-24-hydroxylase activity | molecular function | CYP24A1 |
| 3 iron, 4 sulfur cluster binding | molecular function | SDHB, ACO2, ACO1 |
| 3'(2'),5'-bisphosphate nucleotidase activity | molecular function | BPNT2 |
| 3',5'-cyclic-AMP phosphodiesterase activity | molecular function | PDE4C, PDE7A, PDE7B, PDE1B, PDE4B, PDE3A, PDE3B, PDE4D, PDE8A, PDE2A, PDE8B, PDE4A |
| 3',5'-cyclic-GMP phosphodiesterase activity | molecular function | PDE1C, PDE6A, PDE9A, PDE1B, PDE11A, PDE5A, PDE6G, PDE8A, PDE10A, PDE2A, PDE6B |
| 3',5'-cyclic-nucleotide phosphodiesterase activity | molecular function | PDE4C, PDE6D, PDE1C, PDE7A, PDE1A, PDE7B, PDE6A, PDE9A, PDE1B, PDE4B, PDE3A, PDE3B, PDE11A, PDE4D, PDE5A, PDE6G, PDE8A, PDE10A, PDE2A, PDE6B, PDE8B, PDE4A |
| 3',5'-nucleotide bisphosphate phosphatase activity | molecular function | BPNT2 |
| 3'-5' DNA helicase activity | molecular function | RECQL5, ASCC3, RECQL, MCM5, FBH1, BLM, GINS2, RECQL4, MCM2 |
| 3'-5' exonuclease activity | molecular function | POLG, APEX1, EXOSC10, REV3L, REXO2, REXO4, EXD1, ERI1, EXD3, MRE11, RAD9B, RAD9A, RAD1, TRIR, RAD50, EXD2, APLF, TREX1 |
| 3'-5' RNA helicase activity | molecular function | SUPV3L1 |
| 3'-5'-exodeoxyribonuclease activity | molecular function | TATDN1, MRE11, EXD2, TREX1, POLD1 |
| 3'-5'-exoribonuclease activity | molecular function | EXOSC10, CNOT8, PARN, EXOSC9, ERI2, ISG20, REXO2, TOE1, XRN2, EXOSC7, PAN2, ANGEL2, EXOSC5, ERI1, EXOSC3, DIS3, PNPT1, ERI3, CNOT6L, EXOSC4, EXD2, USB1, DIS3L, EXOSC2, DIS3L2, ISG20L2 |
| 3'-nucleotidase activity | molecular function | BPNT2 |
| 3'-phosphoadenosine 5'-phosphosulfate binding | molecular function | CHST12, GAL3ST3, CHST15, ENPP1, GAL3ST4 |
| 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity | molecular function | SLC35B3 |
| 3'-tRNA processing endoribonuclease activity | molecular function | ELAC1, ELAC2 |
| 3'-tyrosyl-DNA phosphodiesterase activity | molecular function | TDP1 |
| 3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity | molecular function | COQ3 |
| 3-beta-hydroxy-delta5-steroid dehydrogenase activity | molecular function | HSD3B1, HSD3B2, NSDHL, HSD3B7 |
| 3-chloroallyl aldehyde dehydrogenase activity | molecular function | ALDH1A2, ALDH3A2, ALDH3B1 |
| 3-demethylubiquinol-10 3-O-methyltransferase activity | molecular function | COQ3 |
| 3-demethylubiquinone-9 3-O-methyltransferase activity | molecular function | COQ3 |
| 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity | molecular function | FUT5, FUT3 |
| 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity | molecular function | HSD17B10 |
| 3-hydroxy-arachidoyl-CoA dehydratase activity | molecular function | HACD1, HACD2, HACD3 |
| 3-hydroxy-behenoyl-CoA dehydratase activity | molecular function | HACD1, HACD2, HACD3 |
| 3-hydroxy-lignoceroyl-CoA dehydratase activity | molecular function | HACD1, HACD2, HACD3 |
| 3-hydroxyacyl-CoA dehydratase activity | molecular function | HACD1, HACD2, HACD3 |
| 3-hydroxyacyl-CoA dehydrogenase activity | molecular function | HSD17B4, HADH, HSD17B8, HADHB, CRYL1, HADHA, HSD17B10 |
| 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity | molecular function | FASN |
| 3-hydroxyanthranilate 3,4-dioxygenase activity | molecular function | HAAO |
| 3-hydroxybutyrate dehydrogenase activity | molecular function | BDH2, BDH1 |
| 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity | molecular function | FASN |
| 3-hydroxyisobutyrate dehydrogenase activity | molecular function | HIBADH |
| 3-hydroxyisobutyryl-CoA hydrolase activity | molecular function | HIBCH |
| 3-hydroxykynureninase activity | molecular function | KYNU |
| 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity | molecular function | FASN |
| 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity | molecular function | FASN |
| 3-keto sterol reductase activity | molecular function | CBR3, HSD17B7, DHRS11 |
| 3-mercaptopyruvate sulfurtransferase activity | molecular function | MPST |
| 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity | molecular function | BCKDHB, BCKDHA |
| 3-oxo-5-alpha-steroid 4-dehydrogenase activity | molecular function | SRD5A2, SRD5A1, SRD5A3 |
| 3-oxo-arachidoyl-CoA reductase activity | molecular function | HSD17B12 |
| 3-oxo-arachidoyl-CoA synthase activity | molecular function | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| 3-oxo-behenoyl-CoA reductase activity | molecular function | HSD17B12 |
| 3-oxo-cerotoyl-CoA reductase activity | molecular function | HSD17B12 |
| 3-oxo-cerotoyl-CoA synthase activity | molecular function | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| 3-oxo-glutaryl-[acp] methyl ester reductase activity | molecular function | FASN |
| 3-oxo-lignoceronyl-CoA synthase activity | molecular function | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| 3-oxo-lignoceroyl-CoA reductase activity | molecular function | HSD17B12 |
| 3-oxo-pimeloyl-[acp] methyl ester reductase activity | molecular function | FASN |
| 3-oxoacid CoA-transferase activity | molecular function | OXCT2, OXCT1 |
| 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity | molecular function | CBR4, HSD17B8 |
| 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity | molecular function | FASN |
| 3-oxoacyl-[acyl-carrier-protein] synthase activity | molecular function | FASN, OXSM |
| 3-phosphoinositide-dependent protein kinase activity | molecular function | PDPK1 |
| 3-phosphoinositide-dependent protein kinase binding | molecular function | INSR, PTK2B |
| 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity | molecular function | HSD17B4 |
| 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity | molecular function | ACOX2 |
| 4 iron, 4 sulfur cluster binding | molecular function | ERCC2, SDHB, ISCA2, NUBPL, REV3L, PRIM2, EXO5, NFU1, ETFDH, CDK5RAP1, NUBP1, CIAPIN1, NDUFS2, IREB2, ACO2, LIAS, RSAD2, NDUFS1, NTHL1, RTEL1, MUTYH, NUBP2, ISCU, RSAD1, NDUFS8, PPAT, POLE, DPYD, BRIP1, CIAO3, ELP3, ACO1, DDX11, POLD1, CDKAL1, TYW1B, TYW1, NDUFS7, POLA1 |
| 4-alpha-glucanotransferase activity | molecular function | AGL |
| 4-alpha-hydroxytetrahydrobiopterin dehydratase activity | molecular function | PCBD1 |
| 4-aminobutyrate transaminase activity | molecular function | ABAT |
| 4-aminobutyrate:2-oxoglutarate transaminase activity | molecular function | ABAT |
| 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity | molecular function | FUT6, FUT5, FUT9, FUT7, FUT3 |
| 4-hydroxy-2-oxoglutarate aldolase activity | molecular function | HOGA1 |
| 4-hydroxybutyrate receptor activity | molecular function | SLC52A2 |
| 4-hydroxyphenylpyruvate dioxygenase activity | molecular function | HPD |
| 4-nitrophenol 2-monooxygenase activity | molecular function | CYP2E1 |
| 4-trimethylammoniobutyraldehyde dehydrogenase activity | molecular function | ALDH9A1 |
| 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity | molecular function | NSDHL |
| 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity | molecular function | NSDHL |
| 5'-3' DNA helicase activity | molecular function | ERCC2, RUVBL2, RUVBL1, HELB, IGHMBP2 |
| 5'-3' exodeoxyribonuclease activity | molecular function | DCLRE1C, EXO1, DCLRE1B, DCLRE1A |
| 5'-3' exonuclease activity | molecular function | FAN1, FEN1, CPSF3, XRN2, DCLRE1C, EXO1, DXO, DCLRE1B, MRE11, XRN1, TRIR, EXOG |
| 5'-3' exoribonuclease activity | molecular function | DCP2, XRN2, XRN1 |
| 5'-3' RNA helicase activity | molecular function | MOV10, IGHMBP2 |
| 5'-3' RNA polymerase activity | molecular function | TRNT1, TENT2 |
| 5'-deoxynucleotidase activity | molecular function | HDDC2 |
| 5'-deoxyribose-5-phosphate lyase activity | molecular function | POLQ, XRCC5, XRCC6, HMGA2, POLL |
| 5'-flap endonuclease activity | molecular function | FAN1, FEN1, SLX1A, SLX4, EXO1, GEN1 |
| 5'-nucleotidase activity | molecular function | ACPP, NT5DC1, NT5C3B, NT5C1A, NT5C, NT5E, NT5C1B, NT5C2, NT5M, NT5DC2 |
| 5'-tyrosyl-DNA phosphodiesterase activity | molecular function | TDP2 |
| 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding | molecular function | OXER1 |
| 5-amino-4-imidazole carboxylate lyase activity | molecular function | PAICS |
| 5-aminolevulinate synthase activity | molecular function | ALAS1 |
| 5-diphosphoinositol pentakisphosphate 3-kinase activity | molecular function | PPIP5K2 |
| 5-formyltetrahydrofolate cyclo-ligase activity | molecular function | MTHFS |
| 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding | molecular function | OXER1 |
| 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding | molecular function | OXER1 |
| 5-oxoprolinase (ATP-hydrolyzing) activity | molecular function | OPLAH |
| 5S rRNA binding | molecular function | RPL3, RPL5, GTF3A, RPL11, RPF2, EEF2, TST, RRS1 |
| 6,7-dihydropteridine reductase activity | molecular function | QDPR |
| 6-phosphofructo-2-kinase activity | molecular function | PFKFB2, PFKFB4 |
| 6-phosphofructokinase activity | molecular function | PFKM, PFKP, PFKL |
| 6-phosphogluconolactonase activity | molecular function | H6PD, PGLS |
| 6-pyruvoyltetrahydropterin synthase activity | molecular function | PTS |
| 7-dehydrocholesterol reductase activity | molecular function | DHCR7 |
| 7S RNA binding | molecular function | SRP9, SRP19, SRP14, SRP54, SRP72, EXOSC2 |
| 7SK snRNA binding | molecular function | CDK9, CCNT1, DDX21, HEXIM2, HEXIM1 |
| 8-hydroxy-2'-deoxyguanosine DNA binding | molecular function | POT1, BLM |
| 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity | molecular function | NUDT15, NUDT1 |
| 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity | molecular function | OGG1, MUTYH |
| 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity | molecular function | NUDT15, NUDT1 |
| 8-oxo-dGDP phosphatase activity | molecular function | NUDT5 |
| 8-oxo-dGTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| A1 adenosine receptor binding | molecular function | P2RY1 |
| A2A adenosine receptor binding | molecular function | TSNAX, NECAB2 |
| Ac-Asp-Glu binding | molecular function | FOLH1 |
| acetate CoA-transferase activity | molecular function | ACAA1 |
| acetate-CoA ligase activity | molecular function | ACSS3, ACSS1, ACSS2 |
| acetoacetate-CoA ligase activity | molecular function | AACS |
| acetolactate synthase activity | molecular function | ILVBL |
| acetyl-CoA C-acetyltransferase activity | molecular function | ACAT1, ACAA2, HADHA |
| acetyl-CoA C-acyltransferase activity | molecular function | SCP2, ACAA1, ACAA2, HADHB, HADHA |
| acetyl-CoA C-myristoyltransferase activity | molecular function | SCP2, ACAA1, HADHB |
| acetyl-CoA carboxylase activity | molecular function | ACACA, ACACB |
| acetyl-CoA hydrolase activity | molecular function | ACAA2, ACOT9 |
| acetyl-CoA transmembrane transporter activity | molecular function | SLC33A1 |
| acetylcholine receptor activator activity | molecular function | CDK5 |
| acetylcholine receptor activity | molecular function | CHRNA5, CHRNE, CHRNA2, ANXA9, CHRNB1, CHRNA7, CHRND, CHRFAM7A, CHRNA3, CHRNA6, CHRNG, CHRNB2, CHRNA4, CHRNA1, CHRNB4 |
| acetylcholine receptor binding | molecular function | APP, JAK2, RAPSN, UBXN2A, RIC3, LYNX1, RER1, DLG4, PSCA, LY6H |
| acetylcholine receptor inhibitor activity | molecular function | LYPD6, GPIHBP1, LY6G6D, LYNX1, LY6E, LY6H |
| acetylcholine receptor regulator activity | molecular function | FNTA, LYPD6, LYNX1, LYPD6B |
| acetylcholine transmembrane transporter activity | molecular function | SLC18A3, SLC22A1 |
| acetylcholine-gated cation-selective channel activity | molecular function | CHRNA5, CHRNE, CHRNA2, CHRNB1, CHRNA7, CHRND, CHRNA10, CHRNA3, CHRNA6, CHRNG, CHRNB2, CHRNA4, CHRNA1, CHRNB4 |
| acetylcholinesterase activity | molecular function | BCHE |
| acetylesterase activity | molecular function | ABHD2, ABHD1 |
| acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity | molecular function | B3GNT6 |
| acetylgalactosaminyltransferase activity | molecular function | B3GALNT1, CSGALNACT1, B4GALNT1, CHSY1, B3GALNT2, B3GALT2, B3GALT6, CHSY3, B3GALT1, B3GNT5, B3GALT5, CHPF, B3GNT3, B3GNT8, B3GNT4, B4GALNT3, B3GNT6, B4GALNT4, B3GNT9, B3GNT7, B4GALNT2, CSGALNACT2 |
| acetylglucosaminyltransferase activity | molecular function | HEXA, HEXB, B3GALNT1, OGT, EXT1, POMGNT2, B3GALNT2, MGAT4C, MGAT4A, B3GALT2, B3GLCT, EXTL1, B3GALT6, LARGE1, MFNG, B3GALT1, B3GNT5, B3GALT5, EXT2, POMGNT1, B3GNT3, B3GNT8, B3GNT4, MGAT4B, B3GNT6, LFNG, B3GNT9, B3GNT7, MGAT4D |
| acetylputrescine deacetylase activity | molecular function | HDAC10 |
| acetylpyruvate hydrolase activity | molecular function | FAHD1 |
| acetyltransferase activator activity | molecular function | PDCD5, NUPR1, BCAS3 |
| acetyltransferase activity | molecular function | NAT2, NAT1, GTF2B, CREBBP, NAA16, EP300, KAT5, ESCO1, NAA15, ELP3, MOGAT2, KAT2A, CASD1, NAA10, KAT6A, KAT2B, KAT6B |
| acid phosphatase activity | molecular function | ACP1, ACPP, PPIP5K1, MDP1, ACP2, ACP6, MINPP1, ACP4, ACP7 |
| acid sphingomyelin phosphodiesterase activity | molecular function | SMPD1 |
| acid-amino acid ligase activity | molecular function | GHDC |
| acid-sensing ion channel activity | molecular function | ASIC1 |
| acid-thiol ligase activity | molecular function | AASDH, ACSF3 |
| acidic amino acid transmembrane transporter activity | molecular function | SLC1A3 |
| acireductone dioxygenase [iron(II)-requiring] activity | molecular function | ADI1 |
| acireductone synthase activity | molecular function | ENOPH1 |
| aconitate hydratase activity | molecular function | IREB2, ACO2, ACO1 |
| acrosin binding | molecular function | SERPINA5, POMZP3, ZP3 |
| actin binding | molecular function | ACE, MYH7, ITGB1, TMSB4X, MEFV, EZR, CCR5, TWF1, PICK1, TPM1, PIP, NF2, AIF1, MYRIP, MYO19, PACRG, MYO15A, WIPF3, WASL, GC, CAPZA3, EMD, DSTN, HNRNPU, CAMK2B, SETD3, SHROOM3, ARPC1A, CORO1B, SORBS1, COBL, MYH10, CXCR4, ACTR3, DYRK1A, COTL1, MTSS2, PALLD, PAWR, FHDC1, BAIAP2L1, ARPC3, DIAPH2, SLC6A2, IQGAP2, EPB41L1, ABITRAM, VPS18, WASF3, SCIN, SVIL, DMD, YWHAH, FRG1, MYH14, TNS4, ABRA, PPP1R9B, SPTBN5, TPM3, P4HB, TMSB15A, TMSB15B, NEB, SNCA, VASP, PLEC, CNN2, MYO5C, CORO1C, GIPC1, ARPC5, WIPF1, WDR1, FLNB, S100A4, UTRN, CAPZA1, PTK2, NEXN, PLS1, CNN3, JMY, MACF1, EPB41L3, MYH7B, PRKN, PFN2, MARCKSL1, GCSAM, SNTG2, PDLIM1, MYH11, TPM4, SPTBN1, CCDC88A, MAEA, SYNPO, PDLIM2, SNTG1, ABLIM1, MYBPC3, PLEKHH2, MYO3B, MRTFA, PANX1, AIF1L, NOD2, ANLN, HOMER2, CFL2, MYO5A, TMSB4Y, MYH1, HPCA, INF2, VASH2, STK38L, MTSS1, DIAPH1, SYN1, ACTN2, HDGF, DST, CALD1, FLNC, MYBPC2, NRAP, POF1B, PHACTR1, LIMA1, DBNL, TLN2, ALDOA, MICAL3, MYPN, KLHL1, MYO6, MYO9A, SPTBN2, SSH2, PXK, FSCN3, ESPN, TMSB10, EPS8, CDK5R1, COBLL1, FBX |
| actin filament binding | molecular function | EGFR, EZR, PICK1, AIF1, WIPF3, SHTN1, DSTN, SHROOM3, ARPC1A, CORO1B, ANTXR1, MYH10, ACTR3, COTL1, FERMT2, ARPC3, IQGAP1, MYOM2, IQGAP2, ABITRAM, SCIN, SVIL, FRG1, MYH14, PPP1R9B, CTNNA3, TPM3, NEB, CTNNA1, MYO5C, CORO1C, ARPC5, WIPF1, WDR1, MYL4, UTRN, CAPZA1, NEXN, PLS1, RCSD1, IQGAP3, MACF1, MYH7B, TULP1, ZNF185, CTNNA2, MYH11, TPM4, CTTN, AJUBA, FERMT1, ABLIM1, EEF2, MACO1, PANX1, AIF1L, CFL2, MYO5A, MYH1, MYOM3, CORO6, USH1C, ACTN2, NRAP, POF1B, TTN, LIMA1, DBNL, TLN2, MYO18A, MYO6, FSCN3, ESPN, LRPPRC, CDK5R1, ADSS1, CLMN, GAS2L1, NEBL, ACTN1, SLC6A4, MAP1S, ADD3, XIRP2, MYO1B, ABL1, ADD2, CAPZA2, CYFIP1, PKNOX2, FMNL2, ITPRID2, GAS2L3, CTNNAL1, MYO5B, ABL2, CAPZB, ACTR2, TRIOBP, MYO10, BLOC1S6, SPTB, HCLS1, CAPG, FLII, PPP1R9A, MYO1F, LCP1, MYO16, CLASP2, ADD1, TIGD5, TWF2, GAS2L2, WIPF2, VPS16, AVIL, WAS, CORO7, DMTN, LASP1, MPRIP, SAMD14, SYNE2, CORO2B, MYO1C, GJB6, MARCKS, CORO1A, MYH9, ARPC4, FHOD3, TMOD4, ARPC1B, GAS2, TPM2, MISP, MICAL1, TLN1, KPTN, FSCN2, MYH3, MYH6, MYO7A, SHROOM2, TMEM201, MYO7 |
| actin monomer binding | molecular function | NOS3, TMSB4X, TWF1, COBL, MTSS2, ABITRAM, TMSB15A, TMSB15B, MYL4, PFN2, MRTFA, TMSB4Y, MTSS1, LIMA1, TMSB10, COBLL1, ABL1, PKNOX2, ABL2, PRKCE, TWF2, MYL2, CORO1A, MYL3, LMOD2 |
| actin-dependent ATPase activity | molecular function | MYH7, MYH10, MYL6, MYH14, MYO5C, MYO5A, MYO6, MYO1B, MYO5B, MYO10, MYO1F, MYO3A, MYO1C, MYH9, MYH6, MYO7A, MYO7B, MYO1G, MYO1D |
| actinin binding | molecular function | RELA, PKD2, TTN, CSRP3, CSRP1, PDLIM5, TRPC5, MICALL2 |
| activating MHC class I receptor activity | molecular function | CD160 |
| activating transcription factor binding | molecular function | PPARG, GATA4, MEF2A, WFS1, HDAC4, NPM1, PSIP1, HCFC1, FRMD1, RELA, MEF2C, TXLNG, EEF1D, EP300, MEF2D, HDAC7, SMAD2, HOXB4, GABPA, PTMA, CIITA, ZBTB7A, HOXC4, PRDM16, NEK6, DHX33, DGKQ, ZNF516, TAF9, HAND2, HOXA4 |
| active borate transmembrane transporter activity | molecular function | SLC4A11 |
| activin binding | molecular function | TGFBR3, FST, ACVR1B, ACVR1, ACVR2B, FSTL3, TGFBR1, ACVR2A, TGFBR2, ENG, ACVRL1 |
| activin receptor activity, type I | molecular function | ACVR1B, ACVR1, ACVR1C, TGFBR1, ACVRL1 |
| activin receptor activity, type II | molecular function | BMPR2, ACVR2B |
| activin receptor binding | molecular function | TDGF1, CFC1B, MAGI2 |
| acyl binding | molecular function | NDUFAB1 |
| acyl carnitine transmembrane transporter activity | molecular function | SLC25A48, SLC25A29, SLC25A20, SLC25A47 |
| acyl carrier activity | molecular function | NDUFAB1 |
| acyl-CoA dehydrogenase activity | molecular function | ACADM, ACAD11, ACAD9, IVD, ACAD10, GCDH, ACADVL, ACADL, ACADSB, ACAD8, ACADS |
| acyl-CoA delta5-desaturase activity | molecular function | FADS1 |
| acyl-CoA hydrolase activity | molecular function | ACSBG2, ACAA2, BAAT, ACOT13, ACOT9, ACOT7, ACOT2, ACOT11, ACOT4 |
| acyl-CoA ligase activity | molecular function | ACSL3, ACSL1, ACSBG2, ACSM2A, ACSL5, ACSL4, ACSM5, SLC27A2, ACSM3, ACSBG1, ACSM1, ACSF2 |
| acyl-CoA oxidase activity | molecular function | ACOX3, CRAT, ACOX2, ACOX1, ACOXL |
| acyl-L-homoserine-lactone lactonohydrolase activity | molecular function | PON1, PON2 |
| acyl-[acyl-carrier-protein] hydrolase activity | molecular function | OLAH, FASN |
| acylglycerol kinase activity | molecular function | AGK |
| acylglycerol lipase activity | molecular function | ABHD12B, ABHD12, ABHD16A, ABHD2, ABHD16B, ABHD1, ABHD6, PNLIPRP2, MGLL, FAAH |
| acylglycerol O-acyltransferase activity | molecular function | PLA2G15 |
| acyloxyacyl hydrolase activity | molecular function | AOAH |
| acylphosphatase activity | molecular function | ACYP1, ACYP2 |
| acylpyruvate hydrolase activity | molecular function | FAHD1 |
| adenine binding | molecular function | APRT |
| adenine nucleotide transmembrane transporter activity | molecular function | SLC25A5, SLC25A17 |
| adenine phosphoribosyltransferase activity | molecular function | APRT |
| adenine transmembrane transporter activity | molecular function | SLC25A4, SLC25A5 |
| adenine/guanine mispair binding | molecular function | MUTYH |
| adenosine deaminase activity | molecular function | ADAT1, CECR1, ADARB1, LACC1, ADAR, ADAL, ADAD2, ADA, ADARB2 |
| adenosine kinase activity | molecular function | ADK |
| adenosine receptor binding | molecular function | CECR1, USP4 |
| adenosine-diphosphatase activity | molecular function | NUDT9, CANT1, SLC25A42 |
| adenosylmethionine decarboxylase activity | molecular function | AMD1 |
| adenyl deoxyribonucleotide binding | molecular function | TREX1 |
| adenyl nucleotide binding | molecular function | AHCY |
| adenyl ribonucleotide binding | molecular function | PRKAG2 |
| adenyl-nucleotide exchange factor activity | molecular function | HSPH1, GRPEL1, BAG3, SIL1, BAG1, GRPEL2 |
| adenylate cyclase activator activity | molecular function | CALM1, CALM2, CALM3 |
| adenylate cyclase activity | molecular function | ADCY2, ADCY10, ADCY6, ADCY8, ADCY7, ADCY9, ADCY4, ADCY5 |
| adenylate cyclase binding | molecular function | ADCY2, AKAP12, ADRB2, CALM1, CALM2, CALM3, ADCYAP1R1, ADCY5, AKAP5, CAP2, CAP1, AKAP6 |
| adenylate cyclase inhibiting G protein-coupled glutamate receptor activity | molecular function | GRIK3, GRM6 |
| adenylate cyclase inhibitor activity | molecular function | ADGRV1, GRM7 |
| adenylate kinase activity | molecular function | AK2, AK6, AK4, AK1, AK9, AK3, RAD50, AK8, AK7 |
| adenylosuccinate synthase activity | molecular function | ADSS2, ADSS1 |
| adenylylsulfate kinase activity | molecular function | PAPSS2 |
| adenylyltransferase activity | molecular function | TENT2 |
| adipokinetic hormone receptor activity | molecular function | ADIPOR1, ADIPOR2 |
| adiponectin binding | molecular function | ADIPOR1, ADIPOR2, CDH13 |
| ADP binding | molecular function | MSH2, GLUD1, H1-4, CHORDC1, MYH10, COQ8A, GLUD2, GCLC, PRKAG2, RUVBL2, ME1, TAP1, PKM, ATP5F1D, ABCG1, MSH6, MYO18A, MYO6, ERN1, MIEF1, RUVBL1, CYB5R3, PPP5C, P2RY1, MYO3A, ATP1A1, MYH9, ABCD1, MYO7A, MYO9B, LONP1 |
| ADP transmembrane transporter activity | molecular function | SLC25A17, SLC25A42 |
| ADP-dependent NAD(P)H-hydrate dehydratase activity | molecular function | NAXD |
| ADP-ribose diphosphatase activity | molecular function | NUDT9, NUDT5, NUDT6, ADPRM, TRPM2 |
| ADP-ribosyl cyclase activity | molecular function | BST1 |
| ADP-ribosylarginine hydrolase activity | molecular function | ADPRH, ADPRHL1 |
| ADP-ribosylation factor binding | molecular function | RAB11FIP4, GGA3, SORL1, GGA2, GGA1, ADCYAP1R1, RAB11FIP3 |
| ADP-ribosylglutamate hydrolase activity | molecular function | OARD1, MACROD2, MACROD1 |
| ADP-ribosylserine hydrolase activity | molecular function | ADPRS |
| ADP-specific glucokinase activity | molecular function | ADPGK |
| ADP-sugar diphosphatase activity | molecular function | NUDT9, NUDT5 |
| adrenergic receptor activity | molecular function | ADRB2, ADRB3, ADRA2A, ADRA1A, ADRA2B, ADRA1D, ADRB1, ADRA1B, ADRA2C |
| adrenergic receptor binding | molecular function | C1QBP |
| adrenomedullin binding | molecular function | CALCRL, RAMP2 |
| adrenomedullin receptor activity | molecular function | CALCRL, RAMP2, RAMP3 |
| adrenomedullin receptor binding | molecular function | ADM |
| advanced glycation end-product receptor activity | molecular function | AGER |
| AF-2 domain binding | molecular function | NR0B1, ESRRG, PPARGC1B |
| agmatinase activity | molecular function | AGMAT |
| Ala-tRNA(Thr) hydrolase activity | molecular function | DTD2 |
| alanine transmembrane transporter activity | molecular function | SLC38A5 |
| alanine-glyoxylate transaminase activity | molecular function | AGXT |
| alanine-tRNA ligase activity | molecular function | AARS1, AARS2, AARSD1 |
| alanylglutamate dipeptidase activity | molecular function | CNDP2 |
| alcohol binding | molecular function | CDIPT |
| alcohol dehydrogenase (NAD+) activity | molecular function | ADH4, ADH5, DHRS9, ADH1A, ADH6, ADHFE1 |
| alcohol dehydrogenase (NADP+) activity | molecular function | AKR1B1, AKR1A1, AKR1C2, RDH14, AKR1B10, AKR1E2, AKR1D1, AKR1C1, AKR1C4 |
| alcohol dehydrogenase activity, zinc-dependent | molecular function | ADH4, ADH5, ADH1A, ADH6, ADH1B |
| alcohol sulfotransferase activity | molecular function | SULT2B1 |
| alcohol-forming fatty acyl-CoA reductase activity | molecular function | FAR1, FAR2 |
| aldehyde dehydrogenase (NAD) activity | molecular function | ALDH1A2, ALDH9A1, ALDH3A2, ALDH1A3, ALDH2, ALDH1L1, ALDH1A1, ALDH3B1, ALDH4A1, ALDH1L2 |
| aldehyde dehydrogenase [NAD(P)+] activity | molecular function | ALDH1A3, ALDH2, ALDH3B1 |
| aldehyde oxidase activity | molecular function | AOX1 |
| alditol:NADP+ 1-oxidoreductase activity | molecular function | AKR1C3, AKR1B1, ADH4, AKR7A2, AKR1A1, AKR1C2, AKR1B10, AKR1E2, AKR1D1, AKR1C1, AKR1C4 |
| aldo-keto reductase (NADP) activity | molecular function | AKR1C3, CYB5A, KCNAB1, AKR1A1, SPR, AKR1B10, KCNAB3, KCNAB2, AKR1D1, AKR1C1, AKR1C4 |
| aldose 1-epimerase activity | molecular function | GALM |
| aliphatic-amine oxidase activity | molecular function | AOC2, AOC3 |
| alkaline phosphatase activity | molecular function | ALPP, ALPI, CILP2, CILP, ALPL |
| alkane 1-monooxygenase activity | molecular function | CYP4A11, CYP4F8, CYP4F12, CYP4F2 |
| alkenylglycerophosphocholine hydrolase activity | molecular function | TMEM86B, TMEM86A |
| alkenylglycerophosphoethanolamine hydrolase activity | molecular function | TMEM86B, TMEM86A |
| alkyl hydroperoxide reductase activity | molecular function | PRDX3 |
| alkylbase DNA N-glycosylase activity | molecular function | MPG |
| alkylglycerone-phosphate synthase activity | molecular function | AGPS |
| alkylglycerophosphoethanolamine phosphodiesterase activity | molecular function | ENPP2, GNB1, GDPD1 |
| all-trans retinal binding | molecular function | ADH4, CYP2W1 |
| all-trans retinoic acid 18-hydroxylase activity | molecular function | CYP26A1 |
| all-trans-retinol 13,14-reductase activity | molecular function | RETSAT |
| all-trans-retinol binding | molecular function | RBP1, CYP2W1 |
| all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity | molecular function | RPE65 |
| all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity | molecular function | RPE65 |
| allantoicase activity | molecular function | ALLC |
| allyl-alcohol dehydrogenase activity | molecular function | AKR1B1, AKR1A1, AKR1B10 |
| alpha,alpha-trehalase activity | molecular function | TREH |
| alpha-(1,2)-fucosyltransferase activity | molecular function | FUT2 |
| alpha-(1->3)-fucosyltransferase activity | molecular function | FUT4, FUT6, FUT5, FUT9, FUT7, FUT3 |
| alpha-(1->6)-fucosyltransferase activity | molecular function | FUT8 |
| alpha-1,2-mannosyltransferase activity | molecular function | PIGB |
| alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | molecular function | MGAT4C, MGAT4A, MGAT4B |
| alpha-1,3-mannosyltransferase activity | molecular function | ALG2, ALG8, ALG3 |
| alpha-1,4-glucosidase activity | molecular function | GAA, MGAM, GANC |
| alpha-1,4-mannosyltransferase activity | molecular function | PIGM |
| alpha-1,4-N-acetylgalactosaminyltransferase activity | molecular function | EXTL2 |
| alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity | molecular function | MGAT2 |
| alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity | molecular function | MGAT5B |
| alpha-1,6-mannosyltransferase activity | molecular function | PIGV |
| alpha-1A adrenergic receptor binding | molecular function | ARRB2 |
| alpha-1B adrenergic receptor binding | molecular function | ADRA2A, ARRB2 |
| alpha-2 macroglobulin receptor activity | molecular function | LRP1 |
| alpha-2A adrenergic receptor binding | molecular function | GRK2, ADRB1, ADRA2C, UCHL1, APLP1 |
| alpha-2B adrenergic receptor binding | molecular function | APLP1 |
| alpha-2C adrenergic receptor binding | molecular function | ADRA2A, APLP1 |
| alpha-actinin binding | molecular function | ITGB1, PPARG, CACNA1C, PKD2, PKD2L1, SYNPO2, XIRP2, MAGI1, PDLIM4, DAG1, CACNA1D, ADORA2A, KCNN2, RARA |
| alpha-amylase activity | molecular function | AMY2A |
| alpha-catenin binding | molecular function | CTNNB1, NUMB, AJUBA, PTPRT, VCL, PKP2, JUP, PKP3, CDH24, CDH26 |
| alpha-galactosidase activity | molecular function | GLA, NAGA |
| alpha-glucosidase activity | molecular function | MGAM, GANC |
| alpha-glucoside transmembrane transporter activity | molecular function | SLC5A1, SLC5A2 |
| alpha-ketoglutarate transmembrane transporter activity | molecular function | SLC25A21 |
| alpha-L-fucosidase activity | molecular function | FUCA1, FUCA2 |
| alpha-mannosidase activity | molecular function | MAN1B1, MAN2B1, MAN2A1, MAN2A2, MAN2C1, MANEA, MANEAL, MAN2B2 |
| alpha-methylacyl-CoA racemase activity | molecular function | AMACR |
| alpha-N-acetylgalactosaminidase activity | molecular function | NAGA |
| alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity | molecular function | ST6GALNAC6, ST6GALNAC4, ST6GALNAC2, ST6GALNAC5, ST6GALNAC1, ST6GALNAC3 |
| alpha-N-acetylglucosaminidase activity | molecular function | NAGLU |
| alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity | molecular function | ST8SIA2, ST8SIA4, ST8SIA1, ST8SIA5, ST8SIA3 |
| alpha-sialidase activity | molecular function | NEU1 |
| alpha-tocopherol omega-hydroxylase activity | molecular function | CYP4F2 |
| alpha-tubulin binding | molecular function | PACRG, OFD1, EFHC1, HSPH1, FNTA, ARL8B, SLC6A2, BEX4, SNCA, TTLL7, PPARGC1A, BBS4, CAV3, DNAL1, CDK5R1, MAP11, ARL8A, B4GALT1, TAOK1, ARL4C, HDAC6, TBCE, NCALD, DYSF, INO80, FAM110C, SPAST |
| alpha1-adrenergic receptor activity | molecular function | ADRA1A, ADRA1D, ADRA1B |
| alpha2-adrenergic receptor activity | molecular function | ADRA2A, ADRA2B, ADRA2C |
| amidase activity | molecular function | ACR, FAAH |
| amide binding | molecular function | SRD5A2, SRD5A1, PHB2 |
| amide transmembrane transporter activity | molecular function | SLC47A1 |
| amidinotransferase activity | molecular function | GATM |
| amidophosphoribosyltransferase activity | molecular function | PPAT |
| amine N-methyltransferase activity | molecular function | INMT |
| amine sulfotransferase activity | molecular function | SULT1A3 |
| amine transmembrane transporter activity | molecular function | SLC22A2, AQP9, SLC22A16 |
| amino acid binding | molecular function | SHMT1, KARS1, DDAH1, ASS1, DPYS, DDC, AARS1, SLC1A3, AARS2, SHMT2, DDAH2, AGXT, TH, TAT, GOT2, CAD |
| amino acid kinase activity | molecular function | HYKK |
| amino acid transmembrane transporter activity | molecular function | SLC7A5, SLC6A14, SLC6A20, SLC38A9, SLC6A6, SLC1A5, SLC36A4, SLC38A7, SLC38A6, SLC36A1, SLC7A6, SLC38A1, SLC1A4, SLC38A11, SLC7A3, SLC3A1, SLC6A15, SLC7A8, SLC36A2, SLC38A2, SLC38A10, SLC7A9, SLC36A3, SLC38A4, SLC16A10, SLC7A14, SLC7A1, PDPN, SLC43A1, SLC6A12, SLC22A4, SLC38A8, SLC6A19, SLC6A18, SLC43A2, SLC38A5, SLC38A3, SLC32A1, SLC7A2, SLC7A4 |
| amino acid:proton symporter activity | molecular function | SLC36A1, SLC36A2, SLC36A3 |
| amino acid:sodium symporter activity | molecular function | SLC38A1, SLC6A9 |
| aminoacetone:oxygen oxidoreductase(deaminating) activity | molecular function | AOC2, AOC3 |
| aminoacyl-tRNA editing activity | molecular function | IARS1, DTD2, IARS2, DTD1, AARS1, AARS2, LARS1, TARS2, VARS1, LARS2, VARS2 |
| aminoacyl-tRNA hydrolase activity | molecular function | PTRH2, PTRHD1, MRPL58 |
| aminoacyl-tRNA ligase activity | molecular function | FARS2, KARS1, NARS1, MARS1, EPRS1, IARS1, YARS1, HARS1, CARS1, RARS1, DARS2, SARS2, IARS2, WARS1, HARS2, TARS1, CARS2, AARS1, AARS2, DALRD3, LARS1, SARS1, GARS1, PARS2, RARS2, FARSB, AARSD1, NARS2, TARS2, VARS1, QARS1, LARS2, FARSA, TARS3, EARS2, VARS2 |
| aminoacylase activity | molecular function | CAT, ASPA, ACY3 |
| aminobutyraldehyde dehydrogenase activity | molecular function | ALDH9A1 |
| aminomethyltransferase activity | molecular function | GCSH, AMT |
| aminomuconate-semialdehyde dehydrogenase activity | molecular function | ALDH8A1 |
| aminopeptidase activity | molecular function | DPP8, LTA4H, ERAP1, METAP2, ERAP2, BLMH, AOPEP, CTSV, DPP3, LAP3, NPEPPS, RNPEP, NAALADL1, XPNPEP2, METAP1D, PEPD, XPNPEP1, DNPEP, DPP4, XPNPEP3, TPP2, LNPEP, ENPEP, RNPEPL1, KDM8, TRHDE, CTSH, ANPEP, DPP9, NPEPL1, METAP1 |
| aminophospholipid flippase activity | molecular function | TMEM30B, TMEM30A, ATP8A2, ATP8B1 |
| ammonia-lyase activity | molecular function | HAL |
| ammonium transmembrane transporter activity | molecular function | SLC12A2, RHBG, SLC12A6, SLC12A4, AQP1, RHD, SLC12A7, RHCG, RHAG, RHCE |
| AMP binding | molecular function | H1-4, PFKM, PFKP, PRKAG2, FBP1, APRT, ACSS1, MPPED2, CYB5R3, PYGL, PFKL, ACSS2 |
| AMP deaminase activity | molecular function | AMPD2, AMPD3 |
| AMP transmembrane transporter activity | molecular function | SLC25A17, SLC25A42 |
| AMP-activated protein kinase activity | molecular function | PRKAB1, PRKACB, PRKAG2, PRKACG, PRKAA2 |
| amylase activity | molecular function | MGAM |
| amylo-alpha-1,6-glucosidase activity | molecular function | AGL |
| anandamide 11,12 epoxidase activity | molecular function | CYP2D6 |
| anandamide 14,15 epoxidase activity | molecular function | CYP4X1, CYP2D6 |
| anandamide 8,9 epoxidase activity | molecular function | CYP2D6 |
| anandamide amidohydrolase activity | molecular function | FAAH2, FAAH |
| anaphase-promoting complex binding | molecular function | PTEN, CDC20, FZR1, PLK1, CDC20B, CLSPN, UBE2S |
| androgen binding | molecular function | SHBG, AR, ALDH1A1 |
| androgen receptor activity | molecular function | AR |
| androgen receptor binding | molecular function | BRCA1, NRIP1, CTNNB1, PARK7, RB1, NSD1, SMARCA4, RNF14, PRPF6, TRIM68, KDM4C, FOXP1, RNF6, PRMT2, TGFB1I1, PRKCB, EP300, FOXP2, SNW1, WIPI1, ARID5A, PKN1, ZBTB7A, CALR, FOXH1 |
| androstan-3-alpha,17-beta-diol dehydrogenase activity | molecular function | DHRS9, CBR1, RDH5 |
| androsterone dehydrogenase (B-specific) activity | molecular function | AKR1C1 |
| androsterone dehydrogenase activity | molecular function | AKR1C3, DHRS9, AKR1C2, RDH5, AKR1C1, AKR1C4 |
| angiostatin binding | molecular function | ATP5F1B, AMOT, ATP5IF1 |
| angiotensin receptor activity | molecular function | MAS1 |
| angiotensin receptor binding | molecular function | ARRB2 |
| angiotensin type I receptor activity | molecular function | AGTR1 |
| angiotensin type II receptor activity | molecular function | MAS1, AGTR1, AGTRAP |
| anion channel activity | molecular function | VDAC1, GABRB1, SLC26A7, CCT8L2 |
| anion transmembrane transporter activity | molecular function | SLC26A8, SLC4A7, SLC1A2, SLC4A4, SLC26A7, SLC4A2, SLC4A8, SLC26A11, SLC4A1, SLC4A3, SLC26A6, SLC4A10, SLC4A9 |
| anion:anion antiporter activity | molecular function | SLC26A8, SLC26A4, SLC26A3, SLC22A9, SLC26A9, SLC26A5, SLC26A7, SLC26A2, SLC4A2, SLC4A11, SLC4A8, SLC26A11, SLC26A1, SLC4A1, SLC4A3, SLC26A10, SLC26A6, SLC4A10, SLC4A9 |
| anion:cation symporter activity | molecular function | SLC39A8, SLC39A14 |
| ankyrin binding | molecular function | CDH1, PLEC, RHBG, SPTBN1, FLNC, NRCAM, KCNQ2, PTPRC, SLC8A1, OBSCN, SPTB, ATP1A1, CACNA1D, RHCG, SLC4A1, SCN5A, SPTBN4, RHAG |
| ankyrin repeat binding | molecular function | RELA, HIF1AN, SHANK1, TNKS1BP1 |
| annealing helicase activity | molecular function | RECQL, SMARCAL1, SMARCA1, ZRANB3, BLM, RECQL4, RAD54L |
| anti-Mullerian hormone receptor activity | molecular function | AMHR2 |
| antigen binding | molecular function | TGFB1, HFE, ITGA4, HLA-G, AZGP1, TSPAN4, FCN3, CD48, IGLL5, IL7R, FCN1, LILRA2, IGLL1, LILRA1, SLAMF1, ABO, LILRA3, LILRB4, SPON2, CD40, TOPORS |
| antioxidant activity | molecular function | SOD1, APOE, ALB, PRDX4, CAT, PRDX2, PRDX1, S100A9, SELENOS, TP53INP1, UBIAD1, PRDX6, PRXL2B, PRDX3, KDM3B, PRXL2A, PRDX5, SELENOW, MT3, HP, SOD3, APOM, SRXN1 |
| antiporter activity | molecular function | SLC7A5, SLC35E2B, SLC26A3, SLC35A1, TMEM241, SLC35D1, SLC24A5, SLC24A4, CLCN7, SLC35D2, SLC7A6, SLC47A1, SLC9C1, SLC9A2, SLC9A1, SLC9A7, TMCO3, SLC9A9, SLC8A3, SLC47A2, SLC9B2, CLCN3, SLC9C2, SLC8A1, SLC37A4, SLC4A2, SLC35E2A, SLC24A3, SLC25A10, SLC37A1, SLC35E4, SLC9A6, CLCN4, CLCN6, SLC4A8, SLC25A16, SLC35E3, SLC35C1, SLC26A1, LETM1, SLC35D3, SLC4A3, SLC8B1, SLC26A10, SLC38A3, SLC26A6, SLC8A2, CLCN5, SLC4A10, SLC37A2, SLC4A9, SLC24A1 |
| AP-1 adaptor complex binding | molecular function | RAB38, AP1AR, RAB32, SIDT2 |
| AP-3 adaptor complex binding | molecular function | RAB38, RAB32, PI4K2A |
| apelin receptor activity | molecular function | APLNR |
| apolipoprotein A-I binding | molecular function | SCARB1, TREM2, LCAT |
| apolipoprotein A-I receptor activity | molecular function | ABCA7 |
| apolipoprotein A-I receptor binding | molecular function | CDC42, ABCA12, APOA1, NR1H2 |
| apolipoprotein binding | molecular function | CANX, LPL, SCARB1, VLDLR, LIPC, LRP6, TREM2, LRP1, PLG, LRP4, PCSK9 |
| apolipoprotein receptor activity | molecular function | LRP1 |
| apolipoprotein receptor binding | molecular function | APOA1, PCSK9 |
| aquacobalamin reductase (NADPH) activity | molecular function | MTRR |
| arachidonate 12(S)-lipoxygenase activity | molecular function | ALOX12B |
| arachidonate 15-lipoxygenase activity | molecular function | PTGS2, ALOX15B |
| arachidonate 5-lipoxygenase activity | molecular function | ALOX5 |
| arachidonate 8(R)-lipoxygenase activity | molecular function | ALOX12B |
| arachidonate 8(S)-lipoxygenase activity | molecular function | ALOX15B |
| arachidonate-CoA ligase activity | molecular function | ACSL3, ACSL1, ACSBG2, SLC27A3, SLC27A1, ACSL5, ACSL4, SLC27A2, SLC27A4 |
| arachidonic acid 11,12-epoxygenase activity | molecular function | CYP2J2 |
| arachidonic acid 14,15-epoxygenase activity | molecular function | CYP2J2 |
| arachidonic acid binding | molecular function | PPARG, S100A9, ALOX5AP, STX3, S100A8 |
| arachidonic acid epoxygenase activity | molecular function | CYP2B6, CYP2J2, CYP4A11, CYP2A7, CYP2C8, CYP2A6, CYP2C19, CYP2C18, CYP4F12, CYP2E1, CYP4F2, CYP2S1, CYP2C9 |
| arachidonic acid monooxygenase activity | molecular function | CYP4A11, CYP4F3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| arachidonic acid omega-hydroxylase activity | molecular function | CYP4F2 |
| aralkylamine N-acetyltransferase activity | molecular function | AANAT |
| ARF guanyl-nucleotide exchange factor activity | molecular function | ARF4, ARFGEF1, CYTH3, FBXO8, PSD3, ARFGEF2, IQSEC1, PSD2, SEC61B, IQSEC3, PSD, CYTH2, PSD4, GBF1, CYTH4, HERC1, CYTH1, ARFGEF3 |
| arginase activity | molecular function | ARG2 |
| arginine binding | molecular function | NOS3, NOS2, RARS1, PADI4, TM4SF5 |
| arginine decarboxylase activity | molecular function | AZIN2 |
| arginine transmembrane transporter activity | molecular function | SLC7A3, SLC66A1, SLC7A1, SLC7A2 |
| arginine-tRNA ligase activity | molecular function | RARS1, DALRD3, RARS2 |
| argininosuccinate lyase activity | molecular function | ASL |
| argininosuccinate synthase activity | molecular function | ASS1 |
| arginyltransferase activity | molecular function | ATE1 |
| armadillo repeat domain binding | molecular function | TCF7L2, CNOT1, CALCOCO1, CTNNBIP1, AXIN1, STRN, STRN3, STRN4, LEF1, CHD8 |
| aromatase activity | molecular function | CYP1A1, CYP19A1, CYP1A2, CYP1B1, CYP4A11, CYP4F3, CYP2A7, CYP2C8, CYP4F8, CYP4B1, CYP2C19, CYP3A5, CYP2C18, CYP4F12, CYP2E1, CYP4F2, CYP4Z1, CYP2D7, CYP4F11, CYP2C9, CYP3A43 |
| aromatic amino acid transmembrane transporter activity | molecular function | SLC16A10, SLC3A2 |
| aromatic-L-amino-acid decarboxylase activity | molecular function | DDC |
| Arp2/3 complex binding | molecular function | PICK1, CORO1B, IQGAP2, WASF3, JMY, SNX9, WASF2, WASF1, GMFB, AVIL, GMFG |
| arrestin family protein binding | molecular function | ITCH, GPR135, GPR61, ARRDC1, ARRB2, CHRM2 |
| arsenate reductase (glutaredoxin) activity | molecular function | GLRX2 |
| arsenite transmembrane transporter activity | molecular function | GET3 |
| aryl hydrocarbon receptor activity | molecular function | AHR |
| aryl hydrocarbon receptor binding | molecular function | ARNT2, AIP, NCOA1, TAF6, TAF4, ARNTL |
| aryl sulfotransferase activity | molecular function | SULT1E1, SULT1A1, SULT2A1, SULT1B1, SULT1C4, SULT1A3, SULT1A4, SULT1A2 |
| arylamine N-acetyltransferase activity | molecular function | NAT2, NAT1, AANAT |
| aryldialkylphosphatase activity | molecular function | PON1 |
| arylesterase activity | molecular function | PON1, PON2, CA2, APMAP, CA1 |
| arylformamidase activity | molecular function | AFMID |
| arylsulfatase activity | molecular function | ARSA, ARSH, ARSB, ARSD, ARSK, GALNS, SULF1, ARSI, SULF2, ARSG, STS, ARSL |
| asialoglycoprotein receptor activity | molecular function | ASGR2, ASGR1 |
| asparaginase activity | molecular function | ASRGL1, ASPG |
| asparagine synthase (glutamine-hydrolyzing) activity | molecular function | ASNSD1, ASNS |
| asparagine-tRNA ligase activity | molecular function | NARS1, NARS2 |
| aspartate 1-decarboxylase activity | molecular function | CSAD, GADL1 |
| aspartate binding | molecular function | CAD |
| aspartate carbamoyltransferase activity | molecular function | CAD |
| aspartate dehydrogenase activity | molecular function | ASPDH |
| aspartate N-acetyltransferase activity | molecular function | NAT8L |
| aspartate-tRNA ligase activity | molecular function | DARS2 |
| aspartate-tRNA(Asn) ligase activity | molecular function | DARS2 |
| aspartic endopeptidase activity, intramembrane cleaving | molecular function | SPPL2A, SPPL2B, HM13, PSEN1, SPPL3, PSEN2 |
| aspartic-type endopeptidase activity | molecular function | CASP3, CTSD, PIP, SPPL2A, PGC, NRIP3, SPPL2B, HM13, PSEN1, BACE2, ASPRV1, SPPL3, PSEN2, BACE1, NRIP2, DDI1, PGA5, NAPSA |
| aspartic-type endopeptidase inhibitor activity | molecular function | PRNP, ROCK1, NLRP7, WFDC2, CRB2, BIN1 |
| aspartic-type peptidase activity | molecular function | ASTL |
| aspartoacylase activity | molecular function | ASPA |
| AT DNA binding | molecular function | HNRNPD, MEF2C, HMGA2, KMT2A, H1-0, HAND2 |
| Atg12 transferase activity | molecular function | ATG10, ATG3 |
| Atg8 ligase activity | molecular function | ATG3 |
| ATP adenylyltransferase activity | molecular function | KARS1 |
| ATP binding | molecular function | DDX3Y, EGFR, TP53, MYH7, LIG4, FKBP4, AMHR2, TSSK4, TSSK6, AURKC, ERBB2, CDK1, HSP90AA1, ABCB1, MTHFD1, CFTR, FLT1, ERCC2, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, HSPA4, KDR, GSK3B, UBE2B, ADCY2, ATM, PANK2, CHD2, POLQ, FGFR1, PRPS2, CSNK2A2, ABCC1, HSPA9, MTOR, HSPA2, BRSK2, SPO11, MSH4, MSH5, INSR, PGK2, YES1, IGF1R, KIT, HSPA5, SRC, CHKA, MLH1, PIK3CA, MAPK8, PMS2, ATR, BMPR2, LMTK2, DDX4, MLH3, CDC7, PDXK, RAF1, HSPA1A, HSPA1B, HSPD1, MAK, HSPA1L, CLK3, CDK9, ACTB, TWF1, H1FNT, DNAH9, CHD7, DDX25, DICER1, KIF3B, SLC22A5, PGK1, NTRK1, TOP2A, DDR1, CAMK4, KIF26B, MAST2, PPIP5K1, KIF6, DNAH12, DYNC2H1, TDRD9, MYO19, ADCY10, MOV10L1, THG1L, DNAH1, STARD9, MYO15A, KIF3A, CKM, MSH2, LIMK2, DMPK, DYNC1H1, MAPK14, NLRP14, DNAH5, DNAH11, TEP1, XRCC2, FARS2, GLUD1, H1-4, HSPA8, ATP6V1B1, ATP2A2, PRPS1L1, MCM3, KIF5B, RYK, PSMC2, CCT5, CCT4, P2RY4, UBE2D3, KCNJ10, HNRNPU, ROR1, CENPE, CAMK2B, CAMK2D, GK2, DMC1, PDK4, PAN3, DGKK, ATAD2, AACS, NUBPL, HELQ, DDX1, HSPH1, UBE2W, WNK3, DNAH6, TUT1, NMNAT1, PNPL |
| ATP citrate synthase activity | molecular function | ACLY |
| ATP diphosphatase activity | molecular function | NUDT1 |
| ATP transmembrane transporter activity | molecular function | SLC25A4, SLC25A13, SLC25A43, SLC25A48, SLC25A18, SLC25A22, SLC25A41, SLC25A36, SLC25A6, SLC25A5, SLC25A1, SLC25A17, SLC25A24, SLC25A31, SLC25A44, SLC25A16, SLC25A29, SLC25A12, SLC25A25, SLC25A42, SLC25A23, SLC25A21, SLC25A19, SLC25A47 |
| ATP-activated inward rectifier potassium channel activity | molecular function | KCNJ10, ABCC9, KCNJ8, ABCC8, KCNJ1 |
| ATP-binding and phosphorylation-dependent chloride channel activity | molecular function | CFTR |
| ATP-dependent DNA helicase activity | molecular function | ERCC2, CHD2, NBN |
| ATP-dependent helicase activity | molecular function | ERCC2 |
| ATP-dependent microtubule motor activity | molecular function | KIF1B |
| ATP-dependent microtubule motor activity, minus-end-directed | molecular function | DNAH6, DNAH2, DNAH17, DYNC2LI1, DNAH3, DNHD1, DNAH10, DNAH8, KIFC3, KIF25, DNAH14 |
| ATP-dependent microtubule motor activity, plus-end-directed | molecular function | KIF3B, KIF26B, KIF3A, KIF5B, KIF17, KIF1C, KIF19, KIF14, KIF1B, KIF16B, KIF5A, KIF20B, KIF18A, KIF1A, KIF18B, KIF26A, KIF11 |
| ATP-dependent NAD(P)H-hydrate dehydratase activity | molecular function | NAXD |
| ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity | molecular function | N4BP2, CLP1 |
| ATP-dependent polynucleotide kinase activity | molecular function | CLP1 |
| ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity | molecular function | CLP1 |
| ATP-dependent protein binding | molecular function | PLA2G6, PRNP, PLK2, DDX39B, DNAJC5, SAE1 |
| ATP-dependent RNA helicase activity | molecular function | DDX3Y, DDX4, DDX25, TDRD9, MOV10L1 |
| ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity | molecular function | TRNT1 |
| ATP:ADP antiporter activity | molecular function | SLC25A4, SLC25A6, SLC25A5, SLC25A31 |
| ATPase activator activity | molecular function | TOR1AIP1, DNAJC10, DNAJA2, DNAJB4, RAB4A, DNAJC1, DNAJC15, MYBPC3, DNAJC19, DNAJC24, AHSA1, TOR1AIP2, DNAJB1, ATP1B1, GTF2H4, ATP1B2, DNAJB2, ATP1B3, HSCB, ATP4B |
| ATPase activity | molecular function | MYH7, HSP90AA1, ABCB1, CFTR, CLU, ABCC1, HSPA5, MLH1, PMS2, MLH3, HSPA1A, HSPA1B, HSPD1, PICK1, DNAH9, MT-ATP6, MT-ATP8, KIF6, DNAH12, DYNC2H1, MYO19, DNAH1, STARD9, MSH2, DYNC1H1, DNAH5, DNAH11, HSPA8, ATP2A2, KIF5B, PSMC2, ATP5F1C, CENPE, ATAD2, KIF17, KIF2A, DDX3X, ATP6V1G1, KIF20A, ATP5F1B, MYH10, SMARCA2, PSMC6, SRCAP, KIF1C, CLPX, HSPA14, EIF4A2, PSMD6, SWSAP1, SMARCA5, ATP5PF, SMARCA4, PMS1, ATP5F1E, DDX39B, KIF19, ABCC10, KIF24, MYH14, RSF1, KIF15, VPS4B, KATNA1, RFC3, NSF, AK6, PSMC5, KIF14, ABCA12, LONP2, CHD1L, MACF1, RUVBL2, PFN2, ABCA4, TAP1, AFG1L, KIF12, ABCC3, IDE, ATP13A2, OLA1, ACIN1, ATP6V1G2, PSMC3, ATP5F1D, ABCG1, ATP2C1, TAP2, TOR2A, ABCA13, KIFC1, KIF1B, ACTC1, SLFN11, ABCC11, KIF16B, ABCD2, GET3, MSH6, ABCA5, MYO18A, CLPB, DDX39A, ABCC9, CCT8, KIF5A, ABCB5, RNF213, KIF2B, ATP1A2, KIF20B, MDN1, RHOBTB3, SMARCA1, PSMC4, ATF7IP, ATP13A3, ABCB9, RUVBL1, VWA8, HSPA13, SHOC1, KIF18A, KIFC3, SMCHD1, ABCB4, ATP6V1H, PEX1, ATP13A5, KIF27, RAD50, WRNIP1, PAAT, KIF9, ATP8A1, BLM, ATP2A3, ABCB6, A |
| ATPase activity, coupled | molecular function | HSPA1A, HSPA1B |
| ATPase activity, coupled to transmembrane movement of substances | molecular function | ABCB1, CFTR, ABCC1, ATP6V1D, ATP6V1G1, ABCC10, RALBP1, ABCA12, ABCA4, TAP1, ABCC3, ATP6V1G2, ABCG1, TAP2, ABCA13, ABCC11, ABCD2, ABCA5, ATP6V1G3, ABCC9, ABCB5, ABCB9, ABCB4, ABCB6, ABCB10, ABCG4, ABCC5, ABCA7, ABCA10, ABCA3, ABCB8, ABCC6, ABCD1, ABCA2, ABCC4, ABCB11, ABCC8, ABCC12, ABCA6, ABCG2, ABCD4, ABCB7 |
| ATPase binding | molecular function | ESR1, PGR, AR, ATP6V0A2, BRSK2, EZR, WFS1, ANK1, ADCY10, PEX19, SELENOS, ATP6V1G1, TOR1AIP1, DNAJC10, NOP58, DERL1, RALA, CLPP, CHMP4A, SNX10, RAB4A, METTL21A, SDF2L1, RUVBL2, ATP6V1E1, SLN, PEX26, SNU13, SLC26A9, UFD1, PKD2, ATOX1, ALDOB, FXYD4, ATP5IF1, PSEN1, ATXN3, ATP6V1G3, SLC2A13, NSFL1C, RALB, ANK2, FBL, PLN, RAC1, PPP3CA, TOR1AIP2, NUFIP1, RUVBL1, RDX, PDE4D, TMTC4, SVIP, VCPKMT, ZNHIT6, USP25, DNAJB1, GABARAPL2, UBE4B, TRPC1, SYVN1, ATP6V0A4, ATP1B1, TRPC5, ATP1B2, LCK, HRC, TCIRG1, ATP1B3, SNTA1, NKD2, PTPN3, BBC3, FXYD7, UBXN1, TAF9, S100A1, NR1H2, CAV1, ATP6V0A1 |
| ATPase inhibitor activity | molecular function | TSC1, ATP5IF1, PLN, FNIP2, FNIP1 |
| ATPase regulator activity | molecular function | BRSK2 |
| ATPase-coupled anion transmembrane transporter activity | molecular function | CFTR, ABCC1 |
| ATPase-coupled bile acid transmembrane transporter activity | molecular function | ABCC3, ABCB11 |
| ATPase-coupled cation transmembrane transporter activity | molecular function | ATP13A2, ATP7B, ATP1A4, ABCC9, ATP1A2, ATP7A, ATP2B3, ATP8A1, ATP1B1, ATP2B1, KCNJ8, ATP1B3, ATP2B2, ABCC8 |
| ATPase-coupled chloride transmembrane transporter activity | molecular function | PCYOX1 |
| ATPase-coupled fatty-acyl-CoA transmembrane transporter activity | molecular function | ABCD1 |
| ATPase-coupled heme transmembrane transporter activity | molecular function | ABCB6 |
| ATPase-coupled intramembrane lipid transporter activity | molecular function | ATP10B, ATP8B3, ATP8B4, ATP8B2, ATP10D, ABCA4, ATP9B, ATP9A, ATP8A2, ATP11B, ABCB4, ATP11A, ATP8A1, ATP10A, ABCA7, ATP8B1 |
| ATPase-coupled ion transmembrane transporter activity | molecular function | ATP6V0E1, ATP6V0E2, ATP6V1F |
| ATPase-coupled lipid transmembrane transporter activity | molecular function | ABCA12 |
| ATPase-coupled peptide antigen transmembrane transporter activity | molecular function | TAP1, TAP2, TAPBP |
| ATPase-coupled peptide transmembrane transporter activity | molecular function | TAP1, TAP2, ABCB9 |
| ATPase-coupled sterol transmembrane transporter activity | molecular function | ABCG1 |
| ATPase-coupled zinc transmembrane transporter activity | molecular function | SLC30A3 |
| AU-rich element binding | molecular function | NUDT21, EXOSC9, EXOSC7, EXOSC8 |
| axon guidance receptor activity | molecular function | EPHB2, ROBO2, EPHB1, EPHA7, GFRA3, L1CAM, EPHB3, ROBO1 |
| azole transmembrane transporter activity | molecular function | SLC28A2, SLC28A1 |
| basal RNA polymerase II transcription machinery binding | molecular function | LLPH |
| basic amino acid transmembrane transporter activity | molecular function | SLC7A6, SLC7A3, SLC66A1, SLC3A1, SLC7A1, SLC7A7, SLC25A29, SLC7A2, SLC7A4 |
| BAT3 complex binding | molecular function | USP13, SGTA, AMFR |
| bent DNA binding | molecular function | SNAPC3, PIN4 |
| benzaldehyde dehydrogenase (NAD+) activity | molecular function | ALDH1A1, ALDH3B1 |
| benzaldehyde dehydrogenase (NADP+) activity | molecular function | ALDH3B1 |
| benzaldehyde dehydrogenase [NAD(P)+] activity | molecular function | ADH4 |
| benzoate-CoA ligase activity | molecular function | ACSM2A, ACSM1 |
| benzodiazepine receptor activity | molecular function | GABRA2, GABRG2, GABRA5, GABRA4, GABRG1, GABRA1, GABRA3, GABRG3 |
| benzodiazepine receptor binding | molecular function | DBI, RIMBP3B |
| beta,beta-carotene-9',10'-cleaving oxygenase activity | molecular function | BCO2 |
| beta-1 adrenergic receptor binding | molecular function | RAPGEF2, DLG4, SH3GL1, MAGI2 |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity | molecular function | POMGNT1, B3GNT3, B3GNT6 |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity | molecular function | GCNT1 |
| beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity | molecular function | MGAT3 |
| beta-2 adrenergic receptor binding | molecular function | GNAS, SLC9A3R1, NEDD4, PDE4D, AKAP5 |
| beta-2-microglobulin binding | molecular function | HLA-A, HLA-E, HFE, MR1, FCGRT, HLA-F |
| beta-3 adrenergic receptor binding | molecular function | ARRDC3 |
| beta-adrenergic receptor activity | molecular function | ADRB3, ADRB1 |
| beta-adrenergic receptor kinase activity | molecular function | GRK5, GRK2, GRK3, GRK6 |
| beta-amyloid binding | molecular function | APOE, PRNP, IAPP, CD74, GRIN1, FZD4, CRYAB, EPHB2, FBXO2, ITM2C, PGRMC1, LDLR, IDE, SCARB1, FCGR2B, PICALM, APBB2, ADRB2, ITGAM, MARCO, TM2D1, CACNA1A, ITGA2, CHRNA7, BCHE, ATP1A3, APOA1, GRIA2, TGFB2, GPRASP2, GSAP, LRPAP1, APBA2, ITM2A, EPHA4, HSPG2, GRIN2B, SORL1, APBA1, TREM2, RAMP3, ITGB2, LRP1, FPR2, FZD5, CLSTN1, GRIA3, FZD6, C1QA, NGFR, BACE1, GRIN2A, CALCR, APBB1, GRIA1, MAPK8IP2, CACNA1B, COL25A1, TLR6, CD36, AGER |
| beta-amyrin synthase activity | molecular function | LSS |
| beta-aspartyl-peptidase activity | molecular function | ASRGL1, BACE1 |
| beta-carotene 15,15'-monooxygenase activity | molecular function | BCO2, BCO1 |
| beta-catenin binding | molecular function | ESR1, AR, SOX9, GSK3B, KANK1, PROP1, CDH1, FOXO1, NF2, TCF7L2, PTPRJ, GLI3, TCF7, KLF4, ASH2L, SKP1, CARM1, CALCOCO1, PXN, PIN1, TCF7L1, CTNNBIP1, CTNNA3, BTRC, BCL9, KDM6B, CTNNA1, NUMB, DLG5, DVL1, SLC9A3R1, RUVBL2, PRKN, AMER3, LZIC, GSKIP, PTPRT, RORA, MED12L, CBY1, GRIP1, AXIN1, NR4A2, PSEN1, APC, EP300, SUFU, CTNND2, CXADR, BCL9L, TCF4, VCL, PTPRU, LEF1, CD2AP, TBL1X, DACT1, HDAC6, AMER1, AMER2, MED12, CDH5, DVL3, CDHR5, AXIN2, TAX1BP3, FOXO4, SLC9A3R2, SALL1, TRPC4, FOXO3, APC2, CHD8, SHROOM2, AJAP1, SETD1A, CDH24, SMAD3, CDH26, DACT2 |
| beta-catenin destruction complex binding | molecular function | AMER1, LRRK2 |
| beta-endorphin binding | molecular function | IDE |
| beta-galactosidase activity | molecular function | GLB1, PSAP, GLB1L3, GLB1L, GLB1L2 |
| beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | molecular function | ST3GAL4, ST3GAL1, ST3GAL2 |
| beta-galactoside alpha-2,3-sialyltransferase activity | molecular function | ST3GAL6 |
| beta-galactoside alpha-2,6-sialyltransferase activity | molecular function | ST6GAL1, ST6GAL2 |
| beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity | molecular function | B3GNT5, B3GNT3, B3GNT4 |
| beta-glucosidase activity | molecular function | LCT, GBA2, LCTL, KL |
| beta-glucuronidase activity | molecular function | HPSE, GUSB, KL |
| beta-lactamase activity | molecular function | DPEP1 |
| beta-maltose 4-alpha-glucanotransferase activity | molecular function | AGL |
| beta-mannosidase activity | molecular function | MANBA |
| beta-N-acetylgalactosaminidase activity | molecular function | GM2A |
| beta-N-acetylglucosaminidase activity | molecular function | MGEA5 |
| beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity | molecular function | B4GALT2, B4GALT3, B4GALT1, WDFY3 |
| beta-N-acetylhexosaminidase activity | molecular function | HEXA, HEXB, HEXD, GM2A |
| beta-tubulin binding | molecular function | GJA1, PACRG, CCT5, EMD, IFT74, ARL8B, SLC6A2, PDCD5, VAPB, SMC3, TTLL7, ADNP, BBS4, TBCA, RGS2, LRPPRC, CDK5R1, MAP1S, ARL8A, GABARAPL1, PEX14, GABARAP, B4GALT1, TAOK1, GABARAPL2, PIFO, BCAS3, HDAC6, HTT, TBCD, GJB6, APPL1, SPAST |
| beta-ureidopropionase activity | molecular function | UPB1 |
| beta1-adrenergic receptor activity | molecular function | ADRB1 |
| beta2-adrenergic receptor activity | molecular function | ADRB2 |
| beta3-adrenergic receptor activity | molecular function | ADRB3 |
| BH domain binding | molecular function | BAX, BAK1, BCL2L2, BOK, BCL2A1 |
| BH3 domain binding | molecular function | BCL2, BAX, MCL1, RACK1, IRGM, BCL2L1 |
| bHLH transcription factor binding | molecular function | SOX9, SP1, USF1, ISL1, BHLHE40, ASCL1, FHL2, TWIST1, PSMD9, TCF4, LMO2, MAP3K10, RUNX2, ARNTL, USF2, SMAD3, NCAPG2, FOXH1, BHLHE41 |
| bicarbonate binding | molecular function | ADCY10 |
| bicarbonate transmembrane transporter activity | molecular function | CFTR, SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC39A8, SLC26A2, SLC4A11, SLC4A8, SLC26A1, SLC4A1, SLC4A3, SLC26A10, SLC26A6 |
| bile acid binding | molecular function | AKR1C2, NR1H4, PLA2G1B, PYGL, STARD5, AKR1C1, AKR1C4 |
| bile acid receptor activity | molecular function | NR1H4, GPBAR1 |
| bile acid transmembrane transporter activity | molecular function | SLCO1B3, SLCO1A2, SLCO2B1, CEACAM1, SLC51B, ABCB11, SLC10A7, SLCO1C1, AKR1C4 |
| bile acid:sodium symporter activity | molecular function | SLC10A6, SLC10A3, SLC10A2 |
| bile-salt sulfotransferase activity | molecular function | SULT2A1 |
| biliverdin reductase activity | molecular function | BLVRB, BLVRA |
| binding, bridging | molecular function | GAS6, SEPTIN2, LAMTOR3, SEPTIN9, RB1CC1, SEPTIN10, CNOT1, SGTA, PSMG1, IQGAP1, AIMP2, LAMTOR5, RACK1, SLC9A3R1, CAPN3, MPP7, DISC1, SLC9A1, EIF3B, WWC1, CAV3, PSMG3, AXIN1, CAV2, ZMYND10, DLG1, AKAP9, SAV1, PDE4DIP, MAGI1, WWC3, AKAP13, ISCU, CHCHD3, ITSN2, SASH1, LAMTOR1, PKP2, SEPTIN11, TRADD, PCNT, SEPTIN1, SEPTIN5, ANAPC1, SLC9A3R2, SMARCD1, AKAP5, OTUD4, MAGI3, ARRB2, KLHL17, SEPTIN8, PAXX, TMEM250, ITSN1, IPPK, SEPTIN14, MAGI2, PSMG2, SEPTIN3, CAV1, AKAP6, SEPTIN7 |
| bioactive lipid receptor activity | molecular function | FFAR1 |
| biotin binding | molecular function | PCCA, MCCC1, PC, HLCS, ACACB |
| biotin carboxylase activity | molecular function | MCCC1 |
| biotin transmembrane transporter activity | molecular function | SLC27A1, SLC5A6, ABCG2 |
| biotin-protein ligase activity | molecular function | HLCS |
| biotin-[acetyl-CoA-carboxylase] ligase activity | molecular function | HLCS |
| biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity | molecular function | HLCS |
| biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity | molecular function | HLCS |
| biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity | molecular function | HLCS |
| biotinidase activity | molecular function | SIRT4, BTD |
| bis(5'-adenosyl)-hexaphosphatase activity | molecular function | NUDT4, NUDT3 |
| bis(5'-adenosyl)-pentaphosphatase activity | molecular function | NUDT4, NUDT3 |
| bis(5'-adenosyl)-triphosphatase activity | molecular function | FHIT |
| bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity | molecular function | NUDT2, GARS1 |
| bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity | molecular function | NUDT2 |
| bis(5'-nucleosyl)-tetraphosphatase activity | molecular function | NUDT2 |
| bisphosphoglycerate 2-phosphatase activity | molecular function | PGAM1, PGAM4, TIGAR |
| bisphosphoglycerate 3-phosphatase activity | molecular function | MINPP1 |
| bisphosphoglycerate mutase activity | molecular function | PGAM1, PGAM4, BPGM, PGAM2 |
| bitter taste receptor activity | molecular function | TAS2R38, TAS2R9, TAS2R19, TAS2R50, TAS2R60, TAS2R8, TAS2R1, TAS2R39 |
| BLOC-2 complex binding | molecular function | RAB38, RAB32 |
| blue light photoreceptor activity | molecular function | CRY1, CRY2 |
| BMP binding | molecular function | BMPR2, TCAP, CER1, HJV, GREM2, SOSTDC1, ENG, COMP, NBL1, GREM1, GDF5 |
| BMP receptor activity | molecular function | BMPR2, BMPR1A, HJV, SOSTDC1, ACVR2A, ACVRL1 |
| BMP receptor binding | molecular function | BMP7, BMP4, ELAPOR2, BMP5, BMP6, CDH5, PYCARD, BMP2 |
| bombesin receptor activity | molecular function | NMBR, BRS3 |
| box C/D snoRNA binding | molecular function | SNU13 |
| box H/ACA snoRNA binding | molecular function | DKC1, NOP10, NHP2, GAR1 |
| bradykinin receptor activity | molecular function | BDKRB2, BDKRB1 |
| bradykinin receptor binding | molecular function | ACE, AGTR1 |
| brain-derived neurotrophic factor binding | molecular function | NTRK2, FSTL4, HAP1 |
| brain-derived neurotrophic factor-activated receptor activity | molecular function | NTRK2 |
| branched-chain amino acid transmembrane transporter activity | molecular function | SLC25A44 |
| branched-chain-amino-acid transaminase activity | molecular function | BCAT1, BCAT2 |
| BRE binding | molecular function | CELF4 |
| bromide peroxidase activity | molecular function | PXDN |
| bubble DNA binding | molecular function | XPC, ERCC5, HMGB1, ABL1, BLM, RECQL4, NEIL3 |
| butyrate-CoA ligase activity | molecular function | AACS, ACSS3, ACSM2A, ACSM5, ACSM3, ACSM1, ACSF2 |
| butyryl-CoA dehydrogenase activity | molecular function | IVD, ACADS |
| C-22 sterol desaturase activity | molecular function | CYP26A1, CYP26C1 |
| C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity | molecular function | NSDHL |
| C-4 methylsterol oxidase activity | molecular function | MSMO1, CH25H, FAXDC2 |
| C-5 sterol desaturase activity | molecular function | SC5D, FADS1 |
| C-C chemokine binding | molecular function | CCR5, ACKR4, CXCR4, CCR1, XCR1, CXCR5, ACKR3, CXCR2, CCR6, CX3CR1, ZFP36, CCRL2, CXCR3, CXCR1, CCR7, CXCR6, ACKR1, CCR10, CCR3, ACKR2, CCR4 |
| C-C chemokine receptor activity | molecular function | CCR5, ACKR4, CXCR4, CCR1, XCR1, CXCR5, ACKR3, CXCR2, CCR6, CX3CR1, CCRL2, CXCR3, CXCR1, CCR7, CXCR6, GPR75, CCR10, CCR3, ACKR2, CCR4 |
| C-C motif chemokine 19 receptor activity | molecular function | CCR7 |
| C-C motif chemokine 21 receptor activity | molecular function | CCR7 |
| C-rich single-stranded DNA binding | molecular function | PCBP3, PCBP2 |
| C-X-C chemokine binding | molecular function | ACKR3, HMGB1, CXCR3, CXCR6 |
| C-X-C chemokine receptor activity | molecular function | CXCR4, CXCR5, ACKR3, CXCR2, CXCR3, CXCR1, CXCR6, GPR35 |
| C-X-C motif chemokine 12 receptor activity | molecular function | CXCR4 |
| C-X3-C chemokine binding | molecular function | ITGB1, ITGAV, ITGA4, ITGB3, CX3CR1 |
| C-X3-C chemokine receptor activity | molecular function | CX3CR1 |
| C2H2 zinc finger domain binding | molecular function | WT1, MBD2, SRRM2, EHMT2, HMGA2, ZXDC, EHMT1, EBF1, GATA2, LEF1, THAP7, ZXDA, U2AF2, TAF9, GATA1 |
| C3HC4-type RING finger domain binding | molecular function | HSPA1A, HSPA1B, HSPA8, KCNH2, PINK1 |
| C5-methylcytidine-containing RNA binding | molecular function | YBX1, ALYREF |
| C5L2 anaphylatoxin chemotactic receptor binding | molecular function | C3 |
| cadherin binding | molecular function | CTNNB1, CD46, SHTN1, USO1, HSPA8, EEF1G, KIF5B, EMD, EIF3E, RPL24, RPL6, SEPTIN2, CORO1B, GLOD4, SEPTIN9, NUMBL, DDX3X, RPL29, RPL15, RPL7A, EIF4G2, LRRFIP1, IQGAP1, TJP1, ANK3, RTN4, CHMP5, CDH7, SNX2, ATIC, RAB1A, PFKP, TRIM25, PDXDC1, MARK2, ZC3H15, EIF2A, KLC2, CTNNA3, SH3GLB1, BZW2, VAPB, RPS2, NCK1, PAICS, PSMB6, CTNNA1, EIF2S3, NUMB, VASP, RACK1, STX5, PLEC, DAB2IP, BZW1, KTN1, CNN2, GIPC1, FLNB, CAPZA1, RARS1, HDLBP, ACVR1, STK38, PCBP1, FNBP1L, SERBP1, ATXN2L, DCHS1, MACF1, CDH10, CTNND1, HCFC1, ZC3HAV1, LRRC59, CDH19, ARVCF, BAG3, PKM, CTNNA2, EPS15, SPTBN1, CTTN, MPP7, GCN1, CHMP4B, OLA1, ARGLU1, SWAP70, PPME1, EEF2, PRDX6, IST1, PICALM, ANLN, NOP56, EIF5, YWHAZ, PLCB3, CLINT1, DHX29, SNX5, PTPRT, CSNK1D, CALD1, SCRIB, PKP4, EHD4, LIMA1, DBNL, PACSIN2, ALDOA, EEF1D, PSEN1, MRE11, AHNAK, PKN2, EFHD2, DOCK9, PAK6, VAPA, SNX9, SPTBN2, DDX6, RPL34, FASN, CCT8, CDH12, ERC1, MRTFB, EXOC3, AHSA1, PTPRB, APC, TMPO, RPL14, YWHAE, RAN, CDH17, DLG1, CDK5R1, RAB11B, COBLL1, PHLDB2, PUF60, PTPRM, ARHGAP1, ARHGA |
| cadherin binding involved in cell-cell adhesion | molecular function | BAIAP2L1, BAIAP2, EPCAM, CNN3, ANXA1, PDLIM1, STXBP6, KRT18, CDC42EP1, PDLIM5, TMOD3, PAK4, TRIM29, PKP3 |
| cadmium ion binding | molecular function | NOS3, MT3, PRM2 |
| cadmium ion transmembrane transporter activity | molecular function | SLC39A8, SLC11A1, SLC39A14 |
| caffeine oxidase activity | molecular function | CYP1A2, CYP2C8, CYP2C9 |
| calcidiol 1-monooxygenase activity | molecular function | CYP27B1 |
| calcidiol binding | molecular function | GC |
| calcitonin binding | molecular function | CALCR |
| calcitonin gene-related peptide binding | molecular function | RAMP1 |
| calcitonin gene-related peptide receptor activity | molecular function | CALCRL, RAMP1, CALCR, CRCP |
| calcitonin receptor activity | molecular function | CALCRL, CALCR |
| calcitonin receptor binding | molecular function | CALCA, CALCB |
| calcitriol binding | molecular function | VDR |
| calcitriol receptor activity | molecular function | VDR |
| calcium activated cation channel activity | molecular function | CATSPER1, CATSPER2, CATSPER4, ANO6, TMEM63A, PKD2L1, TRPM3, TMEM63C, CALHM1, TRPM4, TMEM63B, ANO1, ANO10, TRPM5 |
| calcium channel activity | molecular function | CATSPER1, CATSPER2, CACNA2D1, PKD1, CATSPER4, CATSPER3, CACNA1S, GRIN1, TRPC3, CACNA1E, SLC24A5, SLC24A4, CACNG2, GPM6A, PKDREJ, RYR1, RYR2, CACNG6, CACNA1C, CACNG3, CACNG7, TMEM37, PANX1, ANXA9, PKD2, PKD2L1, TRPA1, ITPR3, CACNA2D2, CACNA1A, CHRNA7, PSEN1, CUL5, CHRNA10, TRPM3, TRPV2, TRPC7, CACNA1G, ITPR1, CACNA1I, TRPC1, TPCN2, SLC24A3, CACNG4, CACNB4, ITPR2, GRIN3A, TRPC5, CALHM1, CACNA1H, TRPC4, SEC61A1, CACNA1D, CACNB1, CACNG1, GRIN2A, TRPM4, GRIN3B, CACNB3, PKD1L2, TRPM1, TRPV3, TRPM2, CACNA1B, CACNA2D4, MCOLN2, CACNA2D3, TRPM6, TPCN1, CACNB2, CACNG8, TRPV6, SLC24A1, TRPV1 |
| calcium channel inhibitor activity | molecular function | PHPT1, CALM1, CALM2, SLC30A1, FKBP1B, ITPR1, MCUB, AMBP, PACSIN3 |
| calcium channel regulator activity | molecular function | CRISP1, INAFM1, SRI, GRM3, CACNG6, REM2, TSPAN13, NPY, GEM, CACNG7, NRXN2, CAV3, STIMATE, PRKCB, STIM2, YWHAE, PLN, SGK1, PRKG1, SGK3, GRM2, CACNG4, GNB2, REM1, CACNG1, CACNB3, CABP4, CABP2, RRAD, STIM1, CACNG8 |
| calcium ion binding | molecular function | F10, EGF, BGLAP, MGMT, PON1, DLK1, S100A12, GAS6, CIB1, CRP, MAN1B1, AMY2A, HSPA5, MMP12, CD69, PCDH17, CABYR, CDH1, ARSA, CALB2, CDH18, SHH, PLCZ1, ANXA2, AIF1, S100A9, ANXA6, ANXA5, ANXA4, PRF1, PLA2G2A, S100A11, NOX5, PLCH2, PRNP, H1-4, ATP2A2, PAM, LTBP2, EFHC1, CLEC6A, PCDH9, PCDHB9, CALU, ASTN2, CANX, SRI, CETN2, PPP2R3A, EFHC2, CCBE1, FKBP14, PADI1, EEF2K, PLA2G10, MATN4, ANXA7, RCVRN, IQGAP1, MYL6, NUCB2, FAT1, LTBP1, RGN, CAPSL, EDEM2, EDEM3, SLC25A13, CDH7, SCIN, LPL, CAPN2, CPS1, FBN2, GRIN1, ENPP2, RCN1, SYT13, RASGRP3, NIN, NELL1, PLA2G4C, RAPGEF2, PPEF2, MYL12B, PROC, HSP90B1, MYL12A, IDS, FBN1, SNCA, CACNA1E, C2CD5, USP32, CALML6, REPS1, CD93, PCDHGB1, NOTCH2NLC, ANXA3, MYL4, S100A4, CETN1, PLS1, NOTCH2NLA, RAB11FIP4, MCFD2, DCHS1, CAPNS2, PPP3R2, EGFL8, PKDREJ, ANKEF1, MACF1, LOXL2, FKBP7, CDH10, DGKB, CASQ2, CHP2, ANXA1, TPO, THBD, F7, BRAF, PPP3CB, RYR1, S100A5, BNIP2, MCTP2, CRELD2, SNED1, RYR2, FKBP10, CRELD1, ASPN, PITPNM3, CDH19, MATN2, ZZEF1, RASGRP1, LDLR, C1S, CAPN3, EPS15, TPM4, EFCA |
| calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular function | CALB1 |
| calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration | molecular function | CALB1 |
| calcium ion sensor activity | molecular function | SYT1, EFHD1, EFHB |
| calcium ion transmembrane transporter activity | molecular function | TMEM165, ATP2B3, ITPR1, ATP2A3, ITPR2, ATP2B1, SLC8A2 |
| calcium oxalate binding | molecular function | AMBP |
| calcium sensitive guanylate cyclase activator activity | molecular function | RCVRN, GUCA1A, GUCA2B, GUCA1C |
| calcium, potassium:sodium antiporter activity | molecular function | SLC24A5, SLC24A4, SLC24A3, SLC24A1 |
| calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity | molecular function | PDE1C, PDE1A, PDE1B |
| calcium- and calmodulin-responsive adenylate cyclase activity | molecular function | ADCY8 |
| calcium-activated potassium channel activity | molecular function | KCNN3, KCNMB1, KCNMB3, KCNN1, KCNN4, PKD2L1, KCNK18, KCNMA1, KCNMB4, KCNN2, CCT8L2 |
| calcium-dependent ATPase activity | molecular function | ATP2A3, TNNT1, ATP2A1, TNNT3 |
| calcium-dependent carbohydrate binding | molecular function | COLEC11 |
| calcium-dependent cysteine-type endopeptidase activity | molecular function | CAPN2, CAPNS2, CAPN3, CAPNS1, CAPN7, CAPN13, CAPN15, ADGB, CAPN5, CAPN1, CAPN9, CAPN10 |
| calcium-dependent cysteine-type endopeptidase inhibitor activity | molecular function | CAST |
| calcium-dependent phospholipase A2 activity | molecular function | PLA2G2A, PLA2G10, PLA2G4C, PLA2G3, PLA2G4A, PLA2G1B, PLA2G12A, PLA2G5, PLA2G2D |
| calcium-dependent phospholipase C activity | molecular function | PLCH1 |
| calcium-dependent phospholipid binding | molecular function | ANXA2, ANXA6, ANXA5, ANXA4, ANXA7, CPNE8, CPNE3, SYT13, PLA2G4C, C2CD5, ANXA3, ANXA1, MCTP2, SYT1, CPNE2, SYT5, ANXA9, CPNE9, ANXA11, DOC2A, SYT12, SYTL3, MCTP1, ANXA13, CPNE1, ESYT2, CPNE4, PLA2G4A, SYT17, CPNE6, ESYT1, RPH3A, SYT6, CPNE5, SYT9, ESYT3, DYSF, CPNE7, SYT7, SYT2, SYT3, SYT15, DOC2B, SYT10, ANXA8 |
| calcium-dependent protein binding | molecular function | NSMF, A2M, ANXA2, ANXA6, ANXA4, S100A11, S100PBP, ALG2, TSG101, ANXA7, RBM22, CPNE3, SEC31A, ANXA3, S100A4, CASQ2, ANXA1, NRXN1, SPACA9, S100A6, SLC9A1, SYT1, VLDLR, DMBT1, SYN1, SELP, MASP1, ANXA11, CALM3, SNAP25, PDCD6, VPS37C, CHP1, S100P, PDCD6IP, VPS37B, CABP1, S100B, RAC3, SYT6, MASP2, MBL2, PEF1, TNNT3, MYO1D, CPLX2, S100A1 |
| calcium-dependent protein kinase activity | molecular function | PINK1 |
| calcium-dependent protein kinase C activity | molecular function | PRKCH, CCL3, PRKD1, PRKCQ, PKN2, PKN3, PRKD3, PRKCB, PRKCZ, PRKCD, PRKCE, PRKD2, PKN1, PRKCG |
| calcium-dependent protein kinase inhibitor activity | molecular function | CIB1, CAMK2N2 |
| calcium-dependent protein serine/threonine kinase activity | molecular function | CAMK4, MAPKAPK5, MKNK2, MAPKAPK3, MKNK1, CAMK2A |
| calcium-dependent protein serine/threonine phosphatase activity | molecular function | PPP3CA, PPP3R1, CAMK2G |
| calcium-dependent protein serine/threonine phosphatase regulator activity | molecular function | RCAN2, RCAN3, RCAN1 |
| calcium-independent phospholipase A2 activity | molecular function | PLA2G6, PNPLA8, PLA2G4C, PRDX6, PLA2G4A, PLA2G15, PLA2G7, PLA2G5 |
| calcium-independent protein kinase C activity | molecular function | PRKCD, PRKCE |
| calcium-induced calcium release activity | molecular function | RYR1, RYR2, PKD2 |
| calcium-release channel activity | molecular function | RYR1, RYR2, TRPA1, ITPR3, ITPR1, ITPR2, RASA3, TRPM2, TRPV1 |
| calcium-transporting ATPase activity | molecular function | ANXA5, ATP2A2, ATP2C1, ATP2B3, ATP2A3, ATP2B1, ATP2A1, ATP2B2, ATP2C2 |
| calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential | molecular function | ATP2A2 |
| calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular function | ATP2B2 |
| calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration | molecular function | ATP2B3, ATP2B1, ATP2B2 |
| calcium:cation antiporter activity | molecular function | SLC8A3, SLC8B1 |
| calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular function | SLC8A3, SLC8A1, SLC8A2 |
| calcium:proton antiporter activity | molecular function | LETM1 |
| calcium:sodium antiporter activity | molecular function | SLC8A3, SLC8A1, SLC3A2, SLC8B1, SLC8A2 |
| calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential | molecular function | SLC8B1 |
| calmodulin binding | molecular function | MYH7, NOS3, SRY, NOS2, PLA2G6, CAMK4, SPATA17, MYO15A, EWSR1, CAMK2B, CAMK2D, CAMSAP1, MYH10, AKAP12, RIT1, KCNN3, EEF2K, IQGAP1, TJP1, CAMSAP2, IQGAP2, PHKB, GRIN1, MYH14, PDE1C, CNGA2, CNN2, MYO5C, RGS16, CNN3, IQGAP3, CAMK1D, KCNN1, CDK5RAP2, KCNN4, PPP3CB, RYR1, PPP3CC, MARCKSL1, PDE1A, MAPKAPK5, ASPM, RYR2, ARPP21, ITPKB, MYH11, SPTBN1, CACNA1C, MAP6D1, IQCF5, EDF1, SLC9A1, SYT1, PCP4, GEM, MKNK2, MYO5A, MYH1, PLCB3, UBR4, RIT2, KCNQ3, CALD1, CAMKK1, TTN, ATP5IF1, KCNQ2, SLC8A3, PDE1B, MYO6, STRN, PHKG2, MAP2, RGS2, CEP97, UNC13C, MBP, ADCY8, PPP3CA, STRN3, ADD3, UNC13B, MYO1B, IQCF3, SLC8A1, ADD2, EEA1, OBSCN, IQCF2, CTH, ATP2B3, CFAP221, MAP6, MYO5B, CNN1, RGS1, MYO10, STRN4, INVS, PHKA2, DAPK1, SNTB2, SPTAN1, MAPKAPK3, MYO1F, RASGRF2, MYO3A, CASK, PCNT, CEACAM1, ADD1, PPP3R1, SNTB1, AEBP1, REM1, ATP2B1, MKNK1, DAPK2, MYO1C, NGFR, ITPKA, MARCKS, MYH9, KCNQ4, CAMK2G, TRPM4, FBXL2, AKAP5, SNTA1, PHKG1, ENKUR, CAMKK2, IQCF6, MYH3, MYH6, ATP2B2, MYO7A, MYO9B, MYLK, NRGN, UNC13A, MYO1G, SYT7, MYH8, USP6, RR |
| calmodulin-dependent cyclic-nucleotide phosphodiesterase activity | molecular function | PDE1C, PDE1A, PDE1B |
| calmodulin-dependent protein kinase activity | molecular function | CAMK4, CAMK2B, CAMK2D, CAMK1D, CAMKK1, DAPK1, ITPKA, CAMK2G, CAMKK2, CAMK1, MYLK3, PNCK, MYLK2, PTK2B, CAMK2A, CAMKV |
| calmodulin-dependent protein phosphatase activity | molecular function | PPP3CB, PPP3CC, PPP3CA, PPM1A |
| calmodulin-lysine N-methyltransferase activity | molecular function | CAMKMT |
| cAMP binding | molecular function | PRKAR2A, RAPGEF2, CNGA2, BVES, POPDC3, CNBD2, PDE4B, PDE4D, POPDC2, HCN2, HCN1, PRKAR2B, RAPGEF3, PDE10A, PRKAR1B, PDE2A, CNGB1, HCN4, PDE4A, RAPGEF4 |
| cAMP response element binding | molecular function | CREB3, CREB3L2, HMGA2, ATF2, E4F1, CREB3L3, ATF6B, NR4A3 |
| cAMP response element binding protein binding | molecular function | CREM, DDIT3, CRTC3, CREB3, ATF4, ATF2, SIK1, CRTC1 |
| cAMP-dependent protein kinase activity | molecular function | PRKACB, PRKX, PRKACG, AKAP13 |
| cAMP-dependent protein kinase inhibitor activity | molecular function | PRKAR2A, PRKAG2, PKIG, PKIA, PKIB, PRKAR2B, PRKAR1B |
| cAMP-dependent protein kinase regulator activity | molecular function | PRKAR2A, PRKAG2, PRKAR2B, PRKAR1B, CXCL10 |
| canalicular bile acid transmembrane transporter activity | molecular function | ABCB11 |
| cannabinoid receptor activity | molecular function | CNR1, GPR55 |
| carbamoyl-phosphate synthase (ammonia) activity | molecular function | CPS1 |
| carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | molecular function | CPS1, CAD |
| carbohydrate binding | molecular function | KRT1, IL2, CD69, G6PD, UAP1, CLEC7A, PKD1, MAN2B1, GAA, CLEC6A, SIGLEC8, MRC2, LGALS8, CANX, MLEC, LGALS12, EMC7, OLR1, LGALS9, ADGRL1, SORD, REG3A, GALNT2, MAN2A1, CLEC14A, GAL3ST3, LMAN2L, MGAM, LY75, SI, SIGLEC11, CD93, REG1B, FBXO2, GUSB, KLRC1, CD34, SIGLEC6, CHI3L1, LMAN1, LMAN2, COLEC12, BCAN, SIGLEC7, ASGR2, MAN2A2, EVA1C, GANC, CLEC4C, SIGLEC12, CLEC2D, MRC1, KLRC2, AGL, TALDO1, RPIA, DGCR2, CNTN2, CNTN1, REG3G, GALNT13, LGALS14, COLEC11, CD209, KLRG2, FCN3, ACAN, KLRC3, LAYN, GALNT5, GALNT16, LGALS13, SELP, CLEC12A, GALNT4, CLEC2B, CLEC1B, PLA2R1, GALNT10, GALNT15, ADGRL2, GALM, ZG16B, GPCPD1, CRYBG1, FCN1, GALNT1, NPTX2, DCDC1, LGALS2, CLEC3B, LGALS4, OS9, CHI3L2, CLEC4G, GALNT8, STBD1, PYGL, PRG2, NECTIN1, NOMO2, GALNT18, CLEC10A, GALNT11, ITLN1, CD33, SFTPD, KLRG1, MAN2C1, CLEC4A, CD22, MGAT2, CLEC9A, CLEC5A, CDIPT, APCS, SELL, CD72, LGALS7, LGALSL, GALNT12, CLEC4D, MBL2, MAG, PKD1L2, CD248, SIGLEC9, LGALS9B, CLEC18B, GALNT9, MAN2B2, FCER2, CALR, SIGLEC1, NCAN, CLEC2L, NOMO1, GALNTL6, ATRNL1, GAL |
| carbohydrate derivative binding | molecular function | GFPT1, FCN3, FCN1 |
| carbohydrate kinase activity | molecular function | KHK, POMK |
| carbohydrate transmembrane transporter activity | molecular function | TMEM144 |
| carbohydrate:proton symporter activity | molecular function | SLC17A5, SLC2A10, SLC2A8, SLC2A6 |
| carbon dioxide transmembrane transporter activity | molecular function | AQP1, RHAG |
| carbon monoxide binding | molecular function | CBS |
| carbon-carbon lyase activity | molecular function | HACL1 |
| carbon-nitrogen ligase activity, with glutamine as amido-N-donor | molecular function | QRSL1, GATB, GATC |
| carbon-sulfur lyase activity | molecular function | CTH, CENPV |
| carbonate dehydratase activity | molecular function | CA2, CA5A, CA9, CA13, CA14, CA8, CA10, CA12, CA11, CA3, CA7, CA4, CA1 |
| carbonyl reductase (NADPH) activity | molecular function | DHRS2, CBR3, CBR1 |
| carboxy-lyase activity | molecular function | MLYCD, CSAD, PDXDC1, PAICS, PPCDC, AMD1, UROD, ODC1, PCK2, DDC, UXS1, GAD1, GADL1, ECHDC1, UMPS, MVD, PISD, BCKDHA, URAD, GAD2 |
| carboxyl- or carbamoyltransferase activity | molecular function | CAD |
| carboxylic acid binding | molecular function | GRHPR, AKR1C2, PHYH, GOT1, HIF1AN, HMGCL, GOT2, AKR1C1 |
| carboxylic acid transmembrane transporter activity | molecular function | AQP9, SLC16A1 |
| carboxylic ester hydrolase activity | molecular function | LYPLAL1, LPL, CES4A, ABHD5, CES1, LYPLA1, LIPG, SIAE, BAAT, PPME1, AADAC, ABHD2, LIPC, BCHE, ABHD1, ESD, LIPH, ACOT9, ACOT7, ACOT2, ACOT11, CES2, PNLIPRP2, NOTUM, PNLIPRP1, ABHD4, MGLL, PLA1A, NCEH1, PNLIP, ACOT4 |
| carboxypeptidase activity | molecular function | ACE, CPN1, ACE2, AGBL2, AGBL4, CPM, CPVL, BLMH, CPZ, FOLH1B, CPQ, CPXM1, PRCP, NAALADL1, NAALAD2, VASH2, CNDP1, CNDP2, CTSA, CPA3, CPA5, AGBL5, CPD, SCPEP1, FOLH1, CPE, AEBP1, CTSZ, CPA6, CPA1, VASH1, CPA2, AGBL1 |
| CARD domain binding | molecular function | BCL10, NOD2, CARD10, RIPK2, CARD18, CARD19, IRGM, CARD16, CARD8, CARD9, NOD1, CARD14, CARD11, MAVS |
| cardiolipin binding | molecular function | GSDME, STOML2, OPA1, UCP1, MME, NME4, ATP8B1, GSDMD, PLEKHN1, RPE65 |
| cardiolipin synthase activity | molecular function | CRLS1 |
| cargo adaptor activity | molecular function | AP1G1, AP2A2, AP1G2, AP2A1, AP4E1 |
| cargo receptor activity | molecular function | SCARB2, DAB2, VLDLR, ITGAM, MRC1, MARCO, MIA3, ITGB2, LRP1, FPR2, CUBN |
| carnitine O-acetyltransferase activity | molecular function | CRAT |
| carnitine O-octanoyltransferase activity | molecular function | CRAT |
| carnitine O-palmitoyltransferase activity | molecular function | CPT1A, CPT2, CPT1C, CPT1B |
| carnitine transmembrane transporter activity | molecular function | SLC22A5, SLC22A16, SLC22A4 |
| carnosine N-methyltransferase activity | molecular function | CARNMT1 |
| carnosine synthase activity | molecular function | HAO2 |
| carotenoid dioxygenase activity | molecular function | BCO2, BCO1 |
| caspase binding | molecular function | FADD, NLRP7, RIOK3, RIPK2, CARD18, CARD16, MAGEA3, BFAR, NOL3, BCL2L10 |
| catalase activity | molecular function | CAT, LOXHD1, GPX7, CYGB |
| catalytic activity | molecular function | CYP1A1, HSD17B1, RAG1, MEST, OGG1, MTHFD1, MGMT, MTHFR, HSD3B1, ACAT1, HSD3B2, CBS, LYZ, SPO11, AMY2A, XDH, ASAH1, LDHC, ARSA, EPHX2, SPAM1, PGAM1, PGAM4, PSAT1, CDY2A, CDY1, MAN2B1, LDHA, CKM, GAA, MPG, EXOSC10, PMPCB, ALPP, LDHB, PAM, HINT1, AACS, NMNAT1, DERA, CSAD, LANCL1, RNGTT, PAH, PFKM, MTHFD2, BCKDHB, SCP2, GLDC, SHMT1, TKTL1, ECH1, KYNU, NEIL1, ILKAP, NDST4, ACSS3, HACL1, PPM1B, DDAH1, GLA, ALPI, GART, FEN1, MDH2, ACLY, PHKB, CDK5RAP1, EDEM2, EDEM3, GMPR2, EPRS1, FAH, CKMT2, UQCRC2, CPS1, ATIC, FDFT1, MDH1, GYS2, PFKP, ENPP2, ESPL1, MAN2A1, PDXDC1, D2HGDH, GOT1L1, TKTL2, FOLH1B, AGPS, RTCA, MGAM, ECE2, EEF1AKMT4-ECE2, SI, PAICS, IDS, ECHS1, SUCLG1, PLD1, APTX, ECHDC2, APOBEC3F, LARGE2, PPCDC, ABHD8, DIP2B, SUCLA2, LYZL6, MOCS3, GCLC, RABGGTB, PIGH, TKFC, PHLPP2, CAMK1D, GNPAT, UGDH, ACSL3, BRAF, ACSL1, GBE1, ACSBG2, SLC27A3, PLD4, NMNAT3, AASS, ILVBL, PHYH, PNP, ACAA1, ODC1, PKM, IDE, CAPN3, ACAA2, AUH, HLTF, DIP2A, TAB1, HINT3, LANCL2, SLC27A5, ENPP3, POLR2D, LIAS, LARGE1, FBP1, PC, DDC, ERCC5, PRD |
| catechol O-methyltransferase activity | molecular function | COMT, LRTOMT |
| cation binding | molecular function | AMY2A, ILKAP, PPM1B, PARN, GBE1, PPM1L, PPM1K, PPM1G, PDP1, PPM1A, PDP2, PPM1E |
| cation channel activity | molecular function | CATSPER3, ASIC1, SCN11A, ASIC2, GRIN1, TMEM38B, PKD2, PKD2L1, TRPM3, TRPV2, ABCC9, GRIN2C, SCN2A, PIEZO2, CACNA1G, SCN1A, CALHM6, UNC80, MCOLN3, CACNA1I, TRPC1, CALHM5, CALHM1, CACNA1H, GRIN2A, GRIN3B, SCN4A, TRPM1, TRPV3, MCOLN1, CALHM2, TRPM2, SCN5A, PIEZO1, ASIC3, NALCN, MCOLN2, TRPM6, SCN10A, SCN8A, CALHM4, TRPV1 |
| cation transmembrane transporter activity | molecular function | SLC30A9, SLC30A5, CHRNE, SLC41A1, SLC30A2, SLC30A10, PKD2L1, SLC30A8, SLC30A1, SLC30A7, SLC30A3, SLC30A6, SLC8B1, SLC30A4, TRPV1 |
| cation:cation antiporter activity | molecular function | SLC22A5, SLC22A4 |
| cation:chloride symporter activity | molecular function | SLC12A2, SLC12A6, SLC12A4, SLC12A9, SLC12A7, SLC12A5, SLC12A3 |
| CCR chemokine receptor binding | molecular function | CX3CL1, CCL16, CCL20, CCL8, CCL1, CCL14, CCL3, CCL11, CCL22, CCL26, CCL18, CCRL2, CCL23, CCL19, CCL3L1, CCL7, CCL17, CCL21, CCL2, CCL15 |
| CCR1 chemokine receptor binding | molecular function | CCL5, CCL3, CREB3, CCL23, CCL7 |
| CCR10 chemokine receptor binding | molecular function | CCL19 |
| CCR2 chemokine receptor binding | molecular function | CCL7, CCL2 |
| CCR3 chemokine receptor binding | molecular function | NARS1, CCL11, CCL26, CCL27 |
| CCR4 chemokine receptor binding | molecular function | CCL5, CCL17 |
| CCR4-NOT complex binding | molecular function | GARRE1, MARF1 |
| CCR5 chemokine receptor binding | molecular function | STAT3, CCL5, CCL3, CNIH4, NES |
| CCR6 chemokine receptor binding | molecular function | CCL20, DEFB103A, DEFB4A, DEFB1 |
| CCR7 chemokine receptor binding | molecular function | CCL19, CCL21 |
| CD27 receptor binding | molecular function | SIVA1 |
| CD4 receptor binding | molecular function | CD74, SPG21, PLSCR4, PLSCR1, IL16, CD22, LCK |
| CD40 receptor binding | molecular function | TRAF2 |
| CD8 receptor binding | molecular function | LCK |
| CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity | molecular function | PGS1 |
| CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity | molecular function | CDIPT |
| CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity | molecular function | CRLS1 |
| CDP-diacylglycerol-serine O-phosphatidyltransferase activity | molecular function | PTDSS2 |
| CDP-glycerol diphosphatase activity | molecular function | ADPRM |
| cell adhesion molecule binding | molecular function | ITGB1, ITGA5, FGFR1, SRC, ITGA4, CDH1, EZR, CAMLG, NPTN, ADGRL1, VCAM1, NLGN4X, PTPRF, CD226, CTNND1, NRXN1, FGG, PTPN6, NLGN2, NTNG1, NRXN2, POSTN, NRXN3, FGB, DSP, NLGN4Y, ITGB3, TENM2, MSN, CXADR, TGFBI, ITGB7, ITGB2, DSG2, NECTIN1, CPE, CDHR5, FGA, JUP, JAML, SELL, PVR, CLDN7, ADAM8, PKP3, ITGAL, TENM4, CDHR2, TENM3, PTPRD, AFDN, SLC14A2 |
| cell adhesive protein binding involved in AV node cell-bundle of His cell communication | molecular function | CXADR |
| cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication | molecular function | DSP, PKP2, DSG2, DSC2, JUP |
| cell-cell adhesion mediator activity | molecular function | CNTN4, PALLD, NPTN, CD47, NEXN, JAM3, ROBO4, IGSF9, NTNG1, CNTN2, MYPN, DSCAM, ESAM, VSTM2L, PLXNB3, EMB, CNTN6, ROBO3 |
| centromeric DNA binding | molecular function | MLH3, MSH2, ZW10, CENPB, CENPC |
| ceramidase activity | molecular function | ASAH1, ACER3, ACER1, ACER2, ASAH2 |
| ceramidase activity | molecular function | ACER3, ACER1, ACER2, ASAH2 |
| ceramide 1-phosphate binding | molecular function | PLEKHA3, CERT1, CPTP, GLTP, PLA2G4A, PLEKHA8 |
| ceramide 1-phosphate transfer activity | molecular function | PLEKHA3, CERT1, CPTP, GLTP, PLEKHA8, MTTP |
| ceramide binding | molecular function | LAPTM4B, CLN8, CERT1, CD300LF, PLEKHA8 |
| ceramide cholinephosphotransferase activity | molecular function | SGMS2, SAMD8 |
| ceramide glucosyltransferase activity | molecular function | UGCG |
| ceramide kinase activity | molecular function | CERK, AGK |
| ceramide phosphoethanolamine synthase activity | molecular function | SGMS2, SAMD8 |
| ceramide transfer activity | molecular function | CERT1 |
| ceramide-1-phosphate phosphatase activity | molecular function | PLPP2, PLPP1, PLPP3 |
| cerebroside-sulfatase activity | molecular function | ARSA |
| cGMP-dependent protein kinase activity | molecular function | PRKG1 |
| cGMP-inhibited cyclic-nucleotide phosphodiesterase activity | molecular function | PDE3A, PDE3B |
| cGMP-stimulated cyclic-nucleotide phosphodiesterase activity | molecular function | PDE11A, PDE10A, PDE2A |
| CH domain binding | molecular function | SMTNL1 |
| channel activity | molecular function | BCL2, BAX, AQP2, PANX3, AQP11, AQP9, PANX1, PKD2, TRPA1, CHRNB1, AQP3, AQP12A, P2RX7, P2RX6, AQP1, AQP6, CHRNG, TMEM266, AQP10, AQP12B, PANX2, MPV17, STEAP1 |
| channel inhibitor activity | molecular function | BCL2 |
| channel regulator activity | molecular function | CNIH3, SNF8 |
| channel-conductance-controlling ATPase activity | molecular function | CFTR |
| chaperone binding | molecular function | SOD1, TP53, BAX, BAK1, BIRC5, VWF, ALB, CLU, HSPA5, HSPD1, PACRG, PRNP, HSPA8, GRPEL1, PTGES3, DNAJC10, DNAJA4, USP13, FICD, SLC12A2, DNAJA2, ST13, DNAJB4, TIMM9, DNAJB9, GNB5, CTSC, SCARB2, HES1, DNAJC1, SDF2L1, PRKN, BAG4, TSC1, TSACC, BAG3, DNAJB8, PFDN4, BAG5, STUB1, TBCC, WRAP53, FGB, CDC37L1, ATP1A3, BIRC2, TBCA, AHSA1, ATP1A2, LRP2, SLC25A17, CDKN1B, KSR1, SACS, FNIP2, STIP1, ATP7A, DNAJC3, FNIP1, DNAJB1, GET4, GAK, PFDN6, TIMM44, SYVN1, HYOU1, GRN, TBCE, PDPN, BAG1, TBCD, PLG, TIMM10, ATP1A1, UBL4A, DNAJB2, HSPE1, GRPEL2, CALR, BIN1, HSCB, AMFR, CDC37 |
| chemoattractant activity | molecular function | VEGFA, BMP4, CCL5, MIF, HGF, FGF8, SAA1, CCL16, PDGFB, SAA4, CCL3, DEFB103A, GPNMB, DEFB4A, DEFB104A, HMGB1, SAA2, VEGFC, SCG2, FGF7, VEGFB, FGF2, NTF3, ALKBH1, FGF10, CXCL10, CCL15 |
| chemokine (C-C motif) ligand 19 binding | molecular function | CCR7 |
| chemokine (C-C motif) ligand 21 binding | molecular function | CCR7 |
| chemokine (C-C motif) ligand 5 binding | molecular function | CCR5, CCR1 |
| chemokine (C-C motif) ligand 7 binding | molecular function | CCR1 |
| chemokine activity | molecular function | CXCL8, CCL5, CX3CL1, CCL16, CCL20, CCL8, CXCL11, CCL1, CCL14, CCL3, CXCL16, CCL11, C5, CXCL6, CKLF, CCL22, PF4, CXCL2, CCL26, CXCL1, CCL18, CCL23, CCL19, CCL3L1, PPBP, CXCL3, CCL7, CCL28, CXCL14, PF4V1, CXCL12, CCL17, CCL21, CCL27, CXCL10, CCL2, CXCL5, CCL15 |
| chemokine binding | molecular function | ACKR4, CXCR4, CCR1, PLP2, XCR1, CXCR5, ACKR3, CXCR2, CCR6, CX3CR1, CCRL2, CXCR3, PDPN, CXCR1, CCR7, CXCR6, ACKR1, FGF2, CCR10, CCR3, ACKR2, CCR4 |
| chemokine receptor activity | molecular function | CCR5, ACKR4, CXCR4, CCR1, XCR1, CXCR2, CCR6, CX3CR1, CCRL2, CXCR3, CXCR1, CCR7, CXCR6, CCR10, CMKLR1, GPR17, CCR3, ACKR2, CCR4 |
| chemokine receptor antagonist activity | molecular function | CCL5 |
| chemokine receptor binding | molecular function | CCL5, CCRL2, CCL19, CXCL12, CCL21 |
| chemorepellent activity | molecular function | SEMA7A, SEMA3A, NRG1, FLRT3, SEMA3E, SEMA6D, NRG3, SEMA3F, SEMA4C, SEMA3G, SEMA4G, SEMA4D, FLRT2, EFNA5, APOA1, DPP4, SEMA6A, SEMA3B, EPHA7, SEMA3C, SEMA6C, SEMA6B, SEMA4B |
| chenodeoxycholic acid binding | molecular function | NR1H4 |
| chitin binding | molecular function | FIBCD1, CHI3L1, CTBS, CHI3L2, CHID1, OVGP1 |
| chitobiosyldiphosphodolichol beta-mannosyltransferase activity | molecular function | ALG1 |
| chlordecone reductase activity | molecular function | AKR1C4 |
| chloride channel activity | molecular function | CFTR, CLCA4, CLCN2, SLC26A8, GABRB1, GABRA2, CLCN1, CLCNKA, ANO6, FXYD1, CLCN7, TTYH2, SLC1A4, CLIC4, SLC26A9, GABRG2, GABRB3, BEST3, GLRA3, GABRA5, ANO7, SLC26A7, CLCC1, CLIC3, FXYD3, PACC1, GABRB2, GABRA4, CLCNKB, GABRG1, ANO9, CLCN3, CLDN17, CLIC5, GABRP, CLIC1, GABRD, GLRA1, CLIC6, GABRR2, CLCN4, TTYH1, GABRA1, GABRA3, GABRQ, CLDN4, ANO1, ANO2, SLC26A6, TTYH3, GABRR3, ANO4, GABRG3, GLRA2, CLCN5, APOL1 |
| chloride channel inhibitor activity | molecular function | CFTR, WNK3, WNK4, STX8, VTI1B, VAMP8, WNK1, WNK2, STX7 |
| chloride channel regulator activity | molecular function | CFTR, SLC9A3R1, CHRNA7, SGK1, SGK3, TRPV1 |
| chloride ion binding | molecular function | ACE, AMY2A, NLGN4X, CTSC, TDG, NPR3, NUDT16, CLCN3, CLCN4, NQO2, CLCN5 |
| chloride transmembrane transporter activity | molecular function | CFTR, SLC26A4, SLC26A3, CLCN7, SLC26A9, SLC26A5, SLC26A7, SLC26A2, SLC12A5, CLCN6, SLC4A8, SLC26A1, SLC4A1, SLC26A10, SLC26A6 |
| chloride-activated potassium channel activity | molecular function | KCNT2 |
| cholate 7-alpha-dehydrogenase activity | molecular function | HSD17B10 |
| cholate-CoA ligase activity | molecular function | SLC27A5, SLC27A2 |
| cholecystokinin receptor activity | molecular function | CCKAR |
| cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity | molecular function | HSD3B7 |
| cholestenol delta-isomerase activity | molecular function | EBP, EBPL |
| cholestenone 5-alpha-reductase activity | molecular function | SRD5A2, SRD5A1, SRD5A3 |
| cholesterol 24-hydroxylase activity | molecular function | CYP46A1 |
| cholesterol 25-hydroxylase activity | molecular function | CH25H |
| cholesterol binding | molecular function | APOE, NPC2, NR1H3, ANXA6, GRAMD1C, ERLIN1, SCP2, OSBPL1A, STAR, CD81, SULT2B1, SCARB2, OSBPL5, STARD3NL, ABCG1, PMP2, SYP, APOF, OSBPL8, OSBPL2, APOD, APOA1, SOAT1, OSBP2, OSBPL6, NPC1, GRAMD1A, OSBPL10, OSBPL7, ERLIN2, APOA5, SIDT1, NFE2L1, STARD3, STARD4, OSBPL3, STARD5, CETP, PTCH1, GRAMD1B, PROM2, APOC3, CAV1 |
| cholesterol monooxygenase (side-chain-cleaving) activity | molecular function | CYP11A1 |
| cholesterol O-acyltransferase activity | molecular function | SOAT1 |
| cholesterol transfer activity | molecular function | GRAMD1C, SCP2, STAR, ABCG1, OSBPL2, APOA1, GRAMD1A, STARD3, STARD4, STARD5, CETP, GRAMD1B |
| cholesterol transporter activity | molecular function | APOE, APOB |
| choline binding | molecular function | CRP, CHKA, ACPP, BCHE, SLC5A7 |
| choline kinase activity | molecular function | CHKA |
| choline O-acetyltransferase activity | molecular function | CHAT |
| choline transmembrane transporter activity | molecular function | SLC22A2, SLC44A4, SLC44A1, SLC5A7, SLC44A2 |
| choline-phosphate cytidylyltransferase activity | molecular function | PCYT1B, PCYT1A |
| choline:sodium symporter activity | molecular function | SLC5A7 |
| cholinesterase activity | molecular function | CHKA, BCHE |
| choloyl-CoA hydrolase activity | molecular function | BAAT |
| chondroitin 4-sulfotransferase activity | molecular function | CHST12, CHST13, CHST11 |
| chondroitin 6-sulfotransferase activity | molecular function | CHST3, CHST7 |
| chondroitin sulfate binding | molecular function | RTN4R, PTN, DPYSL3, MDK, PTPRS, AGRN, ADGRE2, RTN4RL1 |
| chondroitin sulfate proteoglycan binding | molecular function | PTPRF, PTN, SEMA5A |
| chondroitin-glucuronate 5-epimerase activity | molecular function | DSE, DSEL |
| choriogonadotropin hormone binding | molecular function | LHCGR |
| choriogonadotropin hormone receptor activity | molecular function | LHCGR |
| chromatin binding | molecular function | NR5A2, EGFR, ESR1, TP53, AR, BRD2, BRCA1, SOX9, SOX10, FMR1, NR5A1, DNMT1, HSF1, EZH2, MBD2, DNMT3B, MBD1, DMRT1, POLQ, MTA2, CTNNB1, CSNK2B, MLH1, POLG, NCOA2, EBF2, MLH3, PROP1, PCNA, PPARG, GATA4, CDK9, MEF2A, FOXO1, CHD7, BRD4, RNF8, TOP2A, PRMT6, SIN3A, PYGO2, TP63, LRWD1, TOP1, RBMX, KIAA0101, PATZ1, EED, HMGN1, GLI3, SKIL, HOXD13, FUS, HDAC4, HNRNPU, CBX2, RNF20, ATAD2, MEIOB, DDX1, OVOL2, WAC, MCM8, TRIM24, NUDT21, NPM1, SMARCA2, ISL1, SSBP1, HMGN3, E2F4, SAMD13, SLC30A9, WDR82, IFT74, MTA3, PRDM13, ENY2, MORF4L1, PHF1, AIRE, NKX2-2, ACTL6A, PBX2, NAP1L1, PHC1, CBX1, MBTD1, ZC3H12A, RNF168, NOC3L, NSD1, FAAP24, CALCOCO1, HCFC2, PSIP1, SFPQ, BCL6, SMAD4, HNRNPD, NCOA6, ASXL2, ASXL1, AUTS2, HDAC2, TCF7L1, RERE, KDM6B, CCNT1, SIN3B, TRIM37, EOMES, ATRX, STAT5B, APTX, NAP1L4, TSPYL2, TDRD3, PLAC8, SMC3, PCGF2, NUP62, NCAPD3, ERCC6, SUZ12, TTF1, KMT5B, PAF1, JDP2, SMARCE1, SAMD11, ANKRD2, MCM9, CREB3, NFATC1, HCFC1, FOXA1, OBI1, NCAPH2, TSPYL5, CREBBP, VSX1, PPARGC1A, NUPR1, POLR2B, YBX1, ORC1, NCAPH, GLYR |
| chromatin DNA binding | molecular function | EZH2, STAT3, THRB, APEX1, CLOCK, H1-4, HNRNPU, PER1, ZIC2, BCL6, POLE3, KDM6B, XBP1, MACROH2A2, SUZ12, RUVBL2, H2AZ1, PPARGC1A, SBNO2, SBNO1, NOTCH1, KDM4D, RELA, H1-2, NKAP, UTY, EP300, KDM3B, INSM1, MACROH2A1, FOXC2, H1-0, GRHL1, H1-5, VAX2, SRF, MYOD1, MYOG, H1-1, H1-3, KDM5A, FOXO3, HR, WBP2, ACTN4, THRA, SMAD3, GRHL3, RARA, GATA1 |
| chromo shadow domain binding | molecular function | LBR, ATRX, SP100, NIPBL, CHAF1A |
| chylomicron binding | molecular function | GPIHBP1 |
| ciliary neurotrophic factor binding | molecular function | IL6R |
| ciliary neurotrophic factor receptor activity | molecular function | IL6R, IL6ST, CNTFR, LIFR |
| ciliary neurotrophic factor receptor binding | molecular function | IL6ST, LIFR, CRLF1, CLCF1, CNTF |
| cis-stilbene-oxide hydrolase activity | molecular function | EPHX1 |
| cis-trans isomerase activity | molecular function | PIN1 |
| citrate (Si)-synthase activity | molecular function | CS |
| citrate dehydratase activity | molecular function | ACO2, ACO1 |
| citrate secondary active transmembrane transporter activity | molecular function | SLC25A1 |
| citrate transmembrane transporter activity | molecular function | SLC13A3, SLC25A1, SLC13A1, SLC13A5, SFXN5 |
| citrate-L-glutamate ligase activity | molecular function | RIMKLB |
| class I DNA-(apurinic or apyrimidinic site) endonuclease activity | molecular function | NEIL1, RPS3, NEIL2, NTHL1, ALKBH1, NEIL3 |
| clathrin adaptor activity | molecular function | AP2S1, AP1G1, DAB2, AP2A2, AP1G2, AP2M1, AP2B1, STON1, AP2A1, HIP1R, AP1M1, STON2 |
| clathrin binding | molecular function | SYT13, EPN3, ENTHD1, TOM1, SYT1, PICALM, SYT5, SNAP91, CLINT1, AFTPH, SYT12, SCLT1, AP2B1, TOM1L1, SMAP1, EPN1, GAK, DNAJC6, AP1B1, SYT17, TRPC5, AP4B1, SYT6, NCALD, SYT9, SYT7, HIP1R, EPN2, SYT2, DNER, SYT3, SYT15, BIN1, SYT10, TOM1L2, LRRK2, CLBA1 |
| clathrin heavy chain binding | molecular function | CEMIP, LDLR, PICALM, SNAP91, GPR107, CLTA, LRP1, CLTB |
| clathrin light chain binding | molecular function | NSG2, CLTCL1, CLTC, CALY, NSG1, HIP1R |
| clathrin-uncoating ATPase activity | molecular function | HSPA8 |
| CMP-N-acetylneuraminate transmembrane transporter activity | molecular function | SLC35A1 |
| co-receptor binding | molecular function | HFE, BMP4, WNT9B, WNT3A, DKK1, TFR2, DKK4, BMP2, DKK2, LRRK2 |
| co-SMAD binding | molecular function | USP9Y, GATA4, CITED1, SMAD6, SMAD2, USP9X, TRIM33, TGIF1, SMAD3, FOXH1 |
| CoA carboxylase activity | molecular function | PCCA, MCCC1 |
| CoA-ligase activity | molecular function | ACSBG2, ACSF3, ACSBG1 |
| CoA-transferase activity | molecular function | AMACR, OXCT2, SUGCT, OXCT1 |
| cob(I)yrinic acid a,c-diamide adenosyltransferase activity | molecular function | MMAB |
| cobalamin binding | molecular function | MTR, CD320, MMAB, TCN1, TCN2, MMACHC, CUBN, CBLIF |
| cobalamin transporter activity | molecular function | CD320 |
| cobalamin-transporting ATPase activity | molecular function | ABCC1 |
| cobalt ion binding | molecular function | BIRC5, SHMT1, NUDT16, SHMT2, PML |
| cobalt ion transmembrane transporter activity | molecular function | MMGT1, SLC39A8 |
| cocaine binding | molecular function | SLC6A4 |
| coenzyme A binding | molecular function | HMGCR |
| coenzyme A transmembrane transporter activity | molecular function | SLC25A17, SLC25A42 |
| coenzyme binding | molecular function | ACAT1 |
| cofactor binding | molecular function | BIRC5, C3, DAO |
| collagen binding | molecular function | DCN, MMP9, CD44, VWF, ITGB1, FN1, DDR1, ANTXR1, MRC2, PPIB, CCBE1, CTSK, SMAD4, PDGFB, CTSL, CTSB, GP6, RELL2, ASPN, SPOCK2, USH2A, ITGA10, ITGA2, PDGFA, ABI3BP, ECM2, LOX, COL6A1, ADAM9, C1QTNF1, TGFBI, SPOCK1, CTSS, VTN, MMP13, COL6A2, ITGA9, NID2, HSD17B12, AEBP1, PCOLCE2, COL5A3, P3H1, COMP, PODN, P3H4, ITGA3, PCOLCE, CHADL, SMAD3, ITGA11, COCH, SERPINH1, SPARCL1 |
| collagen binding involved in cell-matrix adhesion | molecular function | ITGB1, ITGA10, ITGA2, ITGA11 |
| collagen fibril binding | molecular function | TNXB, CHADL |
| collagen receptor activity | molecular function | ITGA2, OSCAR, ITGA11 |
| collagen V binding | molecular function | THBS1, ECM2 |
| complement binding | molecular function | CD46, CD59, CFB, CR2, C8G |
| complement component C1q binding | molecular function | CRP, C1QBP, MEGF10, CD93, APCS, CALR |
| complement component C3a receptor activity | molecular function | C3AR1 |
| complement component C3b binding | molecular function | ITGAM, VSIG4, ITGB2 |
| complement component C4b binding | molecular function | MASP2 |
| complement component C5a binding | molecular function | C5AR1 |
| complement component C5a receptor activity | molecular function | C5AR2, C5AR1 |
| complement receptor activity | molecular function | FPR3, CR2, C3AR1, C5AR2, FPR2, CMKLR1, C5AR1 |
| connexin binding | molecular function | GJA1, CNST, CAV3, CXADR, GJA5 |
| COPII adaptor activity | molecular function | TEX261 |
| copper chaperone activity | molecular function | COX17, ATOX1 |
| copper ion binding | molecular function | SOD1, TP53, S100A12, IL1A, ALB, F5, COA6, PARK7, ACR, PRNP, PAM, COX17, LACC1, CUTC, OR5AR1, AOC2, SCO1, SNCA, COX11, LOXL2, S100A5, ADNP, ATP7B, ATOX1, TYR, LOX, COMMD1, HEPH, MT-CO2, AOC1, CUTA, ATP7A, F8, MT3, MOXD1, LOXL3, AOC3, SOD3, GPC1, P2RX4, ANG, DBH, SNAI3, HEPHL1, SCO2, S100A13, DCT |
| copper ion transmembrane transporter activity | molecular function | SLC31A2, ATP7B, ATP7A, SLC31A1 |
| copper transmembrane transporter activity, phosphorylative mechanism | molecular function | ATP7B, ATP7A |
| copper-dependent protein binding | molecular function | FKBP4, ATOX1, ATP7A |
| coproporphyrinogen oxidase activity | molecular function | RSAD1 |
| core promoter binding | molecular function | E2F1, EZH2, PARK7, RB1, CLOCK, NPAS2, RBMX |
| core promoter proximal region DNA binding | molecular function | HNF1B |
| core promoter proximal region sequence-specific DNA binding | molecular function | DMRT1, DMRT2, HOXD13, TFDP1, NR1D2, KLF4, ISL1, NKX2-2, GATA5, CXXC1, TFCP2, XBP1, CREBBP, ELL3, SP3, E2F3, GATA3, MEF2C, TIPARP, MIXL1, NFIC, LHX1, E2F2, SOX11, YY1, TEAD1, ZNF704, UHRF1, ATF2, GATA2, SMAD2, MYOCD, EPAS1, LEF1, RAI1, E2F7, E2F8, NFE2, IRF7, SRF, YY2, MYOD1, MYOG, MTF1, ZNF395, TBX19, ZNF516, FOXN4, ZBTB7B, ESRRB, SMAD3, FOXH1, GATA1 |
| core promoter sequence-specific DNA binding | molecular function | ESR1, TP53, SOX9, NRIP1, ESR2, SP1, CHD2, SOHLH1, PPARG, CLOCK, CREM, SOHLH2, TOP1, NPM1, DR1, GTF2B, FOXP1, JPH2, KLF10, AGO2, SNAPC3, AGO1, ZBTB17 |
| coreceptor activity | molecular function | ITGB1, TGFBR3, IGSF1, ITGAV, ITGA4, CCR5, CD8A, CXCR4, LY96, RGMA, CSPG4, RAMP2, HJV, CD86, ACKR3, LRP6, LILRA4, ITGB3, RGMB, ACVR2A, RAMP3, LRP5, LRP1, NECTIN1, CD4, CXCR6, NGFR, CD28, ENG, NRP1, RAMP1, LRP5L, CD8B, CD80 |
| coreceptor activity involved in canonical Wnt signaling pathway | molecular function | LRP6, LRP5, RECK |
| coreceptor activity involved in Wnt signaling pathway | molecular function | LRP6, LRP5 |
| coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway | molecular function | RYK, ROR1, PTK7, GPC6, GPC4, ROR2 |
| corticosterone 18-monooxygenase activity | molecular function | CYP11B1, CYP11B2 |
| corticotrophin-releasing factor receptor activity | molecular function | CRHR1, CRHR2 |
| corticotropin hormone receptor binding | molecular function | MRAP2 |
| corticotropin receptor activity | molecular function | MC2R |
| corticotropin-releasing hormone activity | molecular function | CRH |
| corticotropin-releasing hormone binding | molecular function | CRHBP, CRHR1 |
| corticotropin-releasing hormone receptor 1 binding | molecular function | GNAS, GNAO1, CRH, UCN |
| corticotropin-releasing hormone receptor 2 binding | molecular function | CRH, UCN, UCN3, UCN2 |
| corticotropin-releasing hormone receptor activity | molecular function | CRHR1, CRHR2 |
| corticotropin-releasing hormone receptor binding | molecular function | UCN3, UCN2 |
| coumarin 7-hydroxylase activity | molecular function | CYP2A6 |
| CP2 mannose-ethanolamine phosphotransferase activity | molecular function | PIGG |
| creatine kinase activity | molecular function | CKM, CKMT2, MAP4K4, CKB |
| creatine transmembrane transporter activity | molecular function | SLC6A8, SLC16A12 |
| creatine:sodium symporter activity | molecular function | SLC6A8 |
| crossover junction endodeoxyribonuclease activity | molecular function | SLX1A, RAD51C, SLX4, TEFM, GEN1, XRCC3 |
| CTP binding | molecular function | HSP90AA1 |
| CTP synthase activity | molecular function | CTPS1, CTPS2 |
| CTP:3'-cytidine-tRNA cytidylyltransferase activity | molecular function | TRNT1 |
| CTP:tRNA cytidylyltransferase activity | molecular function | TRNT1 |
| CTPase activity | molecular function | DDX3X |
| cullin family protein binding | molecular function | DCUN1D1, SKP1, DCUN1D4, KCTD9, PRKN, DCUN1D5, ANAPC11, BTBD1, KLHL36, KLHL21, CCDC22, KCTD17, RBX1, KCTD5, KCTD2, DCUN1D2, DDB1, KLHL9, KLHL13 |
| cupric ion binding | molecular function | PARK7, PRNP, ATP13A2, SUMF1 |
| cupric reductase activity | molecular function | STEAP4, STEAP2, STEAP3 |
| cuprous ion binding | molecular function | PARK7, PRNP, COX17, SNCA, ATP7A |
| CX3C chemokine receptor binding | molecular function | CX3CL1 |
| CXCR chemokine receptor binding | molecular function | ITCH, CXCL11, CXCL6, PF4, CXCL2, CXCL1, PPBP, CXCL3, PF4V1, CXCL12, CXCL10, CXCL5 |
| CXCR3 chemokine receptor binding | molecular function | CXCL11, PF4, CXCL10 |
| CXCR4 chemokine receptor binding | molecular function | TFF2 |
| cyanocobalamin reductase (cyanide-eliminating) activity | molecular function | MMACHC |
| cyclic ADP-ribose hydrolase | molecular function | BST1 |
| cyclic nucleotide binding | molecular function | CNP, FKBP1B |
| cyclic nucleotide-gated ion channel activity | molecular function | CNGB1 |
| cyclic-di-GMP binding | molecular function | STING1 |
| cyclic-GMP-AMP binding | molecular function | STING1 |
| cyclic-GMP-AMP hydrolase activity | molecular function | ENPP1 |
| cyclic-GMP-AMP synthase activity | molecular function | CGAS |
| cyclic-nucleotide phosphodiesterase activity | molecular function | PDE1B, PDE11A, PDE5A, PDE10A |
| cyclin binding | molecular function | CDK1, CDK14, FBXW7, RACK1, CDK15, CDK5RAP3, XRCC6, USP2, CDK13, PROCA1, CDK6, GPS2, CDKN1B, INSM1, KLHDC9, RBM4, MDFIC, GAK, HDAC3, CDKN1A, INCA1, CDK12, PTCH1, CRABP2, FBXO31, POLN, UBE3D |
| cyclin-dependent protein kinase activating kinase activity | molecular function | CDKN1A |
| cyclin-dependent protein serine/threonine kinase activator activity | molecular function | CCNT1, CKS1B, CCNK, CDK5R1, CDK5R2, MNAT1, CKS2 |
| cyclin-dependent protein serine/threonine kinase activity | molecular function | CCNB2, CDK1, CCNB1, MAK, CDK9, MOK, CDK7, CDK14, CDK15, CDKL3, CDKL4, CDK13, CCNK, CDK6, CDKL5, CDK19, CDK18, CDK3, CDKL1, CDK20, CDKL2, CDK12, CDK5, CDK17, CDK11B, CDK11A, CCND3 |
| cyclin-dependent protein serine/threonine kinase inhibitor activity | molecular function | CASP3, CDKN2A, CDKN2B, CDKN2D, HEXIM2, CDKN1B, CDKN2C, CDKN1A, INCA1, CDKN1C, KAT2B, HEXIM1 |
| cyclin-dependent protein serine/threonine kinase regulator activity | molecular function | CCNC, CCNYL1, CCNH, CCNY, CCNT1, CKS1B, CCNJL, CCNI, CCNQ, CCND1, CCNE1, CCNK, CCNL2, CNPPD1, CCNG1, CCNG2, CCNL1, CCNF, CCNE2, CCNP, CCNO, CKS2, CCND3, CCNB3 |
| cystathionine beta-synthase activity | molecular function | CBSL, CBS |
| cystathionine gamma-lyase activity | molecular function | CTH |
| cysteamine dioxygenase activity | molecular function | ADO |
| cysteine desulfurase activity | molecular function | NFS1 |
| cysteine dioxygenase activity | molecular function | CDO1 |
| cysteine synthase activity | molecular function | CBS |
| cysteine-S-conjugate beta-lyase activity | molecular function | KYAT1 |
| cysteine-S-conjugate N-acetyltransferase activity | molecular function | NAT8 |
| cysteine-tRNA ligase activity | molecular function | CARS1, CARS2 |
| cysteine-type carboxypeptidase activity | molecular function | MINDY4, MINDY1, MINDY3, MINDY2 |
| cysteine-type endopeptidase activator activity involved in apoptotic process | molecular function | CASP1, CASP3, BAD, BEX3, RPS27L, RACK1, NKX3-1, NLRP1, ATP2A3, CARD8, NLRP12, CASP8AP2, PYCARD, NOD1, CTSH |
| cysteine-type endopeptidase activity | molecular function | CASP1, CASP4, CASP6, USP1, CASP3, CASP9, CASP8, CTSD, PDIA3, USP8, MALT1, USP9Y, USP38, USP47, USP13, CTSK, USP14, CTSW, BLMH, USP16, ESPL1, CTSV, CTSL, CTSB, CTSC, ATG4A, USP28, USP29, LGMN, USP30, USP37, CASP2, USP33, PYDC1, CFLAR, USP2, CTSF, USP12, USP36, ATG4B, USP7, CASP7, USP48, USP25, TINAG, USP34, USP9X, CTSS, CASP10, ATG4C, USP15, USP11, USP49, RCE1, CTSZ, PYCARD, USP10, USP20, CTSH, USP35, USP6, USP18, USP40, UCHL1, USP5 |
| cysteine-type endopeptidase activity involved in apoptotic process | molecular function | CASP1, CASP4, CASP6, CASP3, CASP9, CASP8, CASP2, CFLAR, CASP7, CASP10, PYCARD |
| cysteine-type endopeptidase activity involved in apoptotic signaling pathway | molecular function | CASP8, CFLAR, CASP10 |
| cysteine-type endopeptidase activity involved in execution phase of apoptosis | molecular function | CASP3, CASP2, CASP7 |
| cysteine-type endopeptidase inhibitor activity | molecular function | BIRC5, LCN1, XIAP, CSTB, CST2, BIRC7, CST11, CST5, NAIP, UBE2Z, CSTA, CAST, SERPINB3, CARD18, BIRC6, SPOCK1, CARD16, WFDC2, CST6, CST7, HRG, CST4, UBE2O, AHSG, FETUB |
| cysteine-type endopeptidase inhibitor activity involved in apoptotic process | molecular function | BIRC5, GAS6, TNFAIP8, XIAP, SNCA, SERPINB9, BIRC7, NAIP, BIRC2, PRDX3, PRDX5, RPS6KA1, LEF1, MT3, TNFSF14, AVP, NOL3, DPEP1, VIL1 |
| cysteine-type endopeptidase regulator activity involved in apoptotic process | molecular function | FOXL2 |
| cysteine-type peptidase activity | molecular function | USP9Y, CASP1, CASP4, CASP6, USP1, CASP3, CASP9, CASP8, USP26, USP8, USP38, USP47, SENP2, USP13, UFSP2, EIF3F, CTSK, USP14, CTSW, BLMH, MINDY4, SENP6, USP16, USP3, CAPN2, ESPL1, MINDY1, MINDY3, CTSV, CTSL, CTSB, USP32, SENP5, CTSC, ATG4A, USP28, USP29, LGMN, CAPN3, USP30, USP51, USP37, OTUD7A, USP22, USP31, OTULIN, CASP2, ATXN3, USP33, CAPN7, CFLAR, USP2, CAPN13, USP45, OTUB2, USP44, USP27X, SENP3, CYLD, CTSF, USP12, CAPN15, USPL1, MINDY2, SENP1, USP36, ATG4B, YOD1, USP7, CASP7, USP48, ALG13, USP25, TINAG, USP4, USP34, USP9X, SENP8, ZRANB1, CAPN5, CAPN1, CTSS, CASP10, ATG4C, TINAGL1, USP15, USP11, USP49, OTUD5, SENP7, PGPEP1, CTSZ, USP10, OTUD6A, UCHL5, PIGK, OTUD4, OTUD7B, CAPN10, USP20, CTSH, USP35, USP21, USP6, USP43, ATG4D, BAP1, USP18, OTUD3, OTUD1, USP40, UCHL1, USP5 |
| cytidine deaminase activity | molecular function | APOBEC3F, CDADC1, CDA, APOBEC3G, APOBEC3A, APOBEC3C, APOBEC3B, APOBEC1, APOBEC2 |
| cytidine transmembrane transporter activity | molecular function | SLC28A1 |
| cytidylate kinase activity | molecular function | CMPK1, AK8, AK7 |
| cytidylyltransferase activity | molecular function | CRPPA |
| cytochrome-b5 reductase activity, acting on NAD(P)H | molecular function | NQO1, POR, CYB5R4, CYB5R2, CYB5R3 |
| cytochrome-c oxidase activity | molecular function | COA6, COX10, CYB5A, MT-CO1, MT-CO3, NDUFA4, COX7A2L, COX7C, COX5A, COX7B2, NMES1, COX7A2, COX7B, COX6A1, COX6C, COX5B, COX6B1, COX8A, MT-CO2, COX4I1, SURF1, NDUFA4L2, COX6A2, COX8C, COX7A1 |
| cytokine activity | molecular function | TIMP1, TGFB1, TNF, IFNG, IL1B, IL4, IL6, INHBA, CXCL8, TGFB3, LIF, VEGFA, IL1RN, IL11, KITLG, IL10, IL12A, TNFSF10, IL18, CMTM2, IL23A, IFNA1, FASLG, NODAL, IL1A, BMP7, GDF15, GDF9, BMP15, IL5, BMP4, CCL5, MIF, IL2, NRG1, IL17A, IL21, INHA, IL33, CSF1, CX3CL1, CCL16, AREG, CCL20, TNFSF15, IL15, NDP, CCL8, TNFRSF11B, IL7, CMTM7, CXCL11, CER1, CCL1, FAM3B, CCL14, TSLP, TNFSF12, CCL3, SPP1, CTF1, CMTM3, WNT10A, CXCL16, IFNA8, CCL11, WNT7B, LTB, IL1F10, IL17C, IL13, WNT4, CXCL6, ADIPOQ, IL34, IL17D, WNT9B, WNT3A, IL20, GDF11, NAMPT, IFNL1, CKLF, CCL22, PF4, IL3, WNT2B, WNT8B, SCGB3A1, IFNA10, HMGB1, BMP1, IL27, FAM3D, GREM2, IL36RN, C17orf99, FAM3C, BMP5, TGFB2, TAFA5, IL25, TNFSF13B, CXCL2, CCL26, LEFTY1, GPI, AIMP1, CXCL1, CCL18, CMTM1, CRLF1, SCG2, OSM, BMP6, TNFSF4, CCL23, IL16, CCL19, IL36G, WNT11, CSF3, IL32, GRN, TNFSF14, CCL3L1, IFNL3, IL19, WNT10B, MSTN, IFNA2, IFNA14, PPBP, EDN1, BMP2, CXCL3, CCL7, THNSL2, IL17F, GDF3, CCL28, CXCL14, FGF2, TNFSF8, INHBC, INHBE, IL24, GDF7, PF4V1, TNFSF9, EBI3, VSTM1, EP |
| cytokine binding | molecular function | PARK7, KIT, ELANE, IL13RA2, CXCR4, CD74, CSF3R, FZD4, IFNGR1, IL12RB1, CNTFR, IL13RA1, TNFRSF9, IL23R, CRLF2, LIFR, NRP2, GHR, GBP1, CRLF1, TNFRSF14, CHRD, IL2RG, TNFRSF11A, IL11RA, IL17F, OSMR, IL12RB2, IL5RA, IL31RA, NRP1, EBI3, CSF1R, IL27RA |
| cytokine receptor activity | molecular function | IL6R, CD44, IL6ST, F3, PRLR, LEPR, IL13RA2, CD74, CSF2RB, CSF3R, FZD4, IFNGR1, IL20RB, IL22RA2, IL12RB1, IL9R, IFNGR2, IL15RA, IL10RA, CNTFR, IL13RA1, IL23R, CRLF2, IFNAR1, LIFR, EPOR, GHR, IL21R, IL7R, MPL, CX3CR1, IL1RL1, CRLF1, IL2RB, IL2RG, IL11RA, OSMR, IL12RB2, IL5RA, IL22RA1, IL31RA, IL10RB, EBI3, IL27RA, IL4R |
| cytokine receptor binding | molecular function | IL4, IFNA1, MIF, IL17A, IL21, IL15, IL7, IFNA8, IL13, IFNA10, IFNA2, IFNA14, IL17F, IFNW1 |
| cytosine C-5 DNA demethylase activity | molecular function | ALKBH3 |
| cytosine deaminase activity | molecular function | APOBEC1 |
| cytoskeletal adaptor activity | molecular function | ANK1, BAIAP2, ANK3, NCK1, ABI2, BICD1, NCK2, SORBS2, ANK2, GAS2L1, SDCBP, BICD2, OBSL1, GAS2L3, GAS2L2, GAS2, BIN3 |
| cytoskeletal protein binding | molecular function | EZR, ANXA2, TPM1, NF2, PSTPIP1, SORBS1, DES, DYRK1A, TOR1AIP1, ANK3, EPB41L1, CAPN2, CRYAB, PLEC, DLG5, LIN7C, FCHO1, MACF1, EPB41L3, FABP3, GAS7, PKD2, PKD2L1, ALDOB, ACTN2, DST, FLNC, PACSIN2, ALDOA, MYPN, EPB41L5, DLG1, MYLIP, FARP1, FRMD3, NEBL, MSN, SLC8A1, FCHO2, ABI1, RDX, CNTRL, EPB41L4B, ACTR2, PIFO, LDB3, DUSP3, PSTPIP2, FARP2, CDK5, PDLIM3, ALDOC, CORO1A, CRK, FRMD5, PTPN4, CAPN10, NCKIPSD, KRT2, PACSIN3, BIN3, RPH3AL, EPB41, PTPN3, PACSIN1, EPB41L2, SGIP1 |
| cytoskeletal regulatory protein binding | molecular function | CDC42EP3 |
| cytoskeleton-nuclear membrane anchor activity | molecular function | SYNE2, SUN2, SYNE1 |
| cytosolic dipeptidase activity | molecular function | CNDP2 |
| D-amino-acid oxidase activity | molecular function | DAO, DDO |
| D-aminoacyl-tRNA deacylase activity | molecular function | DTD2, DTD1 |
| D-aspartate oxidase activity | molecular function | DDO |
| D-erythro-sphingosine kinase activity | molecular function | SPHK2 |
| D-glucose transmembrane transporter activity | molecular function | SLC2A10, SLC2A4, SLC5A1, SLC5A2 |
| D-glutamate cyclase activity | molecular function | DGLUCY |
| D-lactate dehydrogenase (cytochrome) activity | molecular function | LDHD |
| D-lactate dehydrogenase activity | molecular function | LDHD |
| D-ribitol-5-phosphate cytidylyltransferase activity | molecular function | CRPPA |
| D-ribulokinase activity | molecular function | FGGY |
| D-serine ammonia-lyase activity | molecular function | SRR |
| D-serine transmembrane transporter activity | molecular function | SFXN1 |
| D-tyrosyl-tRNA(Tyr) deacylase activity | molecular function | DTD2, DTD1 |
| D-xylose 1-dehydrogenase (NADP+) activity | molecular function | DHDH |
| D-xylulose reductase activity | molecular function | SORD |
| D1 dopamine receptor binding | molecular function | GNAS, PTPN11, PPP1R1B, SNX5, PTGER1, CAV2, DLG4, DRD3, ARRB2, VPS35 |
| D2 dopamine receptor binding | molecular function | PPP1R9B, PPP1R1B, CLIC6, DNM1 |
| D3 dopamine receptor binding | molecular function | PPP1R1B, PALM, CLIC6 |
| D3 vitamins binding | molecular function | CYP2R1 |
| D4 dopamine receptor binding | molecular function | PPP1R1B, CLIC6 |
| D5 dopamine receptor binding | molecular function | PPP1R1B, GNA12 |
| damaged DNA binding | molecular function | TP53, BRCA1, OGG1, ERCC1, MGMT, XRCC1, XPA, POLQ, RAD23A, RAD23B, MSH4, MSH5, PCNA, H2AFX, APEX1, XPC, TP63, NBN, MPG, MSH2, RBBP8, REV1, NEIL1, POLH, XRCC5, RPA2, FEN1, APTX, RPS3, DDB2, RPA1, CREBBP, POLK, DCLRE1C, TDG, KDM4D, NEIL2, FANCG, XRCC6, MSH6, DCLRE1B, HMGB1, RAD1, EP300, SDE2, POLI, RPA3, TP53BP1, ERCC4, DCLRE1A, POLB, NEIL3, AUNIP, POLD1, CRY2, UNG, RAD18, DDB1 |
| dATP binding | molecular function | HSP90AA1, H1-4, ST13 |
| dATP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| dATP pyrophosphohydrolase activity | molecular function | NUDT1 |
| dCMP deaminase activity | molecular function | CDADC1, DCTD |
| dCTP diphosphatase activity | molecular function | DCTPP1 |
| dCTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| deacetylase activity | molecular function | NDST4, HDAC2, MACROD2, AADAC, NDST1, NDST3, SIRT6, SIRT7, NDST2, HDAC10, MACROD1, YDJC |
| DEAD/H-box RNA helicase binding | molecular function | POT1, ETV3, SP7, AKAP8L, SMAD3, SMAD5 |
| deaminase activity | molecular function | CECR1, AMPD2, RIDA, ADAL, ADA, AMPD3, GDA |
| death domain binding | molecular function | DAP, TRADD, CRADD |
| death effector domain binding | molecular function | CASP8, FADD, CASP10 |
| death receptor activity | molecular function | TNFRSF10A, NGFR |
| death receptor agonist activity | molecular function | EDA |
| death receptor binding | molecular function | CASP3, FASLG, CASP8, BEX3, DAB2IP, MYD88, FEM1B, FADD, BID, CFLAR, TMBIM1, PIDD1, MADD, EDA, CASP8AP2 |
| decanoate-CoA ligase activity | molecular function | ACSL3, ACSL1, ACSBG2, ACSL5, ACSL4, SLC27A2, ACSBG1, ACSM1 |
| decaprenyldihydroxybenzoate methyltransferase activity | molecular function | COQ3 |
| dehydroascorbic acid transmembrane transporter activity | molecular function | SLC2A10, SLC2A14, SLC2A8, SLC23A1, SLC2A6 |
| dehydrodolichyl diphosphate synthase activity | molecular function | NUS1 |
| delayed rectifier potassium channel activity | molecular function | KCNA4, KCNH2, KCNQ3, KCNG1, KCNQ2, KCNG4, KCNC4, KCNB1, KCNE4, KCNA6, KCNS3, KCNG2, KCNE1, KCNA2, KCNC1, KCNQ4, KCNC2, KCNA3, KCNA1, KCNC3, KCNG3, KCNQ5, KCNE3 |
| delta-catenin binding | molecular function | PTPRJ, PTPRT, DACT1, CDH24, CDH26, DACT2 |
| delta14-sterol reductase activity | molecular function | LBR, TM7SF2 |
| delta24(24-1) sterol reductase activity | molecular function | DHCR24 |
| delta24-sterol reductase activity | molecular function | DHCR24 |
| delta3,5-delta2,4-dienoyl-CoA isomerase activity | molecular function | ECH1 |
| delta4-3-oxosteroid 5beta-reductase activity | molecular function | AKR1C3, AKR1D1 |
| demethylase activity | molecular function | CYP1A1, CYP1A2, ALKBH4, MMACHC |
| denatured protein binding | molecular function | HSPA1A |
| deoxyadenosine kinase activity | molecular function | DCK, DGUOK |
| deoxycytidine deaminase activity | molecular function | APOBEC3F, APOBEC3G, APOBEC3A, APOBEC3C, APOBEC3B |
| deoxycytidine kinase activity | molecular function | DCK, TK2 |
| deoxycytidyl transferase activity | molecular function | REV1 |
| deoxyguanosine kinase activity | molecular function | DCK, DGUOK |
| deoxyhypusine monooxygenase activity | molecular function | DOHH |
| deoxynucleoside kinase activity | molecular function | DCK, DGUOK, TK2 |
| deoxynucleotide transmembrane transporter activity | molecular function | SLC25A19 |
| deoxyribonuclease activity | molecular function | ENDOG, MAP1S, DFFB, DNASE1L3, NME1, DNASE1, DNASE1L1 |
| deoxyribonuclease I activity | molecular function | DICER1, DNASE1L3, DNASE1, DNASE1L1 |
| deoxyribonuclease II activity | molecular function | DNASE2B, DNASE2 |
| deoxyribonuclease inhibitor activity | molecular function | DFFA |
| deoxyribonucleoside 5'-monophosphate N-glycosidase activity | molecular function | DNPH1 |
| deoxyribose-phosphate aldolase activity | molecular function | DERA |
| dephospho-CoA kinase activity | molecular function | COASY, DCAKD |
| deubiquitinase activator activity | molecular function | TANK |
| dGTP binding | molecular function | SAMHD1 |
| dGTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| dGTPase activity | molecular function | SAMHD1 |
| DH domain binding | molecular function | EPHA4 |
| diacylglycerol binding | molecular function | RASGRP3, CHPT1, RAPGEF2, RASGRP1, RASGRP4, RASGRP2, UNC13C, UNC13B, CDIPT, UNC13A, DGKD |
| diacylglycerol cholinephosphotransferase activity | molecular function | CEPT1, CHPT1, CDS1 |
| diacylglycerol diphosphate phosphatase activity | molecular function | PLPP1, PLPP5, PLPP4 |
| diacylglycerol kinase activity | molecular function | DGKK, DGKE, DGKB, DGKI, DGKA, DGKG, DGKZ, DGKH, DGKQ, DGKD, AGK |
| diacylglycerol O-acyltransferase activity | molecular function | MOGAT1, DGAT2, DGAT1, MOGAT2, MOGAT3 |
| diamine N-acetyltransferase activity | molecular function | SAT1, SATL1, SAT2, KAT2B |
| diamine oxidase activity | molecular function | AOC1 |
| dicarboxylic acid transmembrane transporter activity | molecular function | SLC13A3, SLC25A10 |
| digestive hormone activity | molecular function | SCT |
| dihydroceramidase activity | molecular function | ACER3, ACER1, ACER2, ASAH2 |
| dihydroceramide glucosyltransferase activity | molecular function | UGCG |
| dihydroceramide kinase activity | molecular function | CERK, AGK |
| dihydrofolate reductase activity | molecular function | DHFR2, DHFR |
| dihydrolipoamide S-acyltransferase activity | molecular function | DLAT |
| dihydrolipoyllysine-residue acetyltransferase activity | molecular function | DLAT |
| dihydrolipoyllysine-residue succinyltransferase activity | molecular function | DLST |
| dihydronicotinamide riboside quinone reductase activity | molecular function | NQO2 |
| dihydroorotase activity | molecular function | CAD |
| dihydroorotate dehydrogenase activity | molecular function | DHODH |
| dihydropyrimidine dehydrogenase (NADP+) activity | molecular function | DPYD |
| dihydrotestosterone 17-beta-dehydrogenase activity | molecular function | AKR1C3, HSD17B10 |
| diiodophenylpyruvate reductase activity | molecular function | MDH1 |
| dimethylargininase activity | molecular function | DDAH1, DDAH2 |
| dimethylglycine dehydrogenase activity | molecular function | DMGDH |
| dinitrosyl-iron complex binding | molecular function | GSTP1 |
| dinucleotide insertion or deletion binding | molecular function | PCNA, MSH2 |
| dinucleotide repeat insertion binding | molecular function | MSH2 |
| diolein transacylation activity | molecular function | PNPLA3 |
| dioxygenase activity | molecular function | PTGS1, PTGS2, PLOD1, KDM5C, KDM5D, HAAO, P3H3, KDM5B, ASPHD2, IDO2, PIR, KDM6B, RIOX2, KDM4A, ALKBH7, PHF2, IDO1, RIOX1, PHYH, ETHE1, ADO, KDM4C, KDM4D, PLOD2, HGD, BCO2, ASPHD1, P4HA3, UTY, P4HA1, CDO1, KDM3B, PHF8, TET3, RSBN1L, OGFOD3, ADI1, KDM2A, ALOX5, TET1, KDM4B, ASPH, RSBN1, EGLN1, ALOXE3, HIF1AN, ALKBH3, ALKBH4, PLOD3, EGLN2, TYW5, P3H1, TMLHE, KDM5A, ALKBH1, ALKBH6, PHYHD1, TET2, KDM8, OGFOD1, ALOX15B, P4HA2, ALOX12B, OGFOD2, JMJD4, HPD, ALKBH5, BCO1 |
| dipeptidase activity | molecular function | FOLH1B, DPEP3, NAALAD2, CNDP1, CNDP2, SCRN3, PEPD, PM20D2, FOLH1, SCRN2, DPEP2, SCRN1, DPEP1 |
| dipeptide transmembrane transporter activity | molecular function | SLC15A2, SLC15A1 |
| dipeptidyl-peptidase activity | molecular function | DPP6, DPP8, DPEP3, DPP3, PRCP, NAALAD2, DPP4, DPEP2, DPEP1 |
| diphosphoinositol-pentakisphosphate kinase activity | molecular function | PPIP5K1, PPIP5K2 |
| diphosphoinositol-polyphosphate diphosphatase activity | molecular function | NUDT4B, NUDT4, NUDT3 |
| diphosphomevalonate decarboxylase activity | molecular function | MVD |
| diphthine methylesterase activity | molecular function | DPH7 |
| diphthine synthase activity | molecular function | DPH5 |
| diphthine-ammonia ligase activity | molecular function | DPH6 |
| disaccharide binding | molecular function | LGALS9 |
| disordered domain specific binding | molecular function | KEAP1, NCOA3, AP2A2, MYO5A, CALM1, CALM2, CALM3, RRM1, TEAD2, NUMA1, CLTC, SMAD2, DFFB, GJA5, FKBP8, KCNA1, SMTNL1, TP53, HSPA1A |
| disulfide oxidoreductase activity | molecular function | PDIA3, DNAJC10, TMX1, TXNL1, PDIA2, TMX2 |
| dITP diphosphatase activity | molecular function | ITPA, NUDT16 |
| divalent inorganic cation transmembrane transporter activity | molecular function | SLC41A1 |
| DNA (cytosine-5-)-methyltransferase activity | molecular function | DNMT1, DNMT3B |
| DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates | molecular function | DNMT1, DNMT3B |
| DNA 5'-adenosine monophosphate hydrolase activity | molecular function | APTX |
| DNA binding | molecular function | NR5A2, DDX3Y, ESR1, PRM1, TP53, PGR, AR, VDR, RAG1, ATF3, WT1, AHR, BRCA1, SOX9, LIG4, BRCA2, SOX10, NR5A1, HIF1A, NOSTRIN, ESR2, TERT, OGG1, ZEB2, NR1I2, PRM2, ERCC1, SP1, MGMT, ERCC2, HNF1A, XPA, DNMT1, MAPK1, HNF1B, SOX3, STAT1, NR0B1, HSF1, E2F1, HSF2, SRY, ATM, STAT4, EZH2, NFE2L2, CDKN2A, CTCFL, ARNT2, MBD2, DNMT3B, MBD1, PLAGL1, DMRT1, CHD2, POLQ, MTA2, ALB, NR3C1, APP, ENO1, TNP1, PARP1, CTNNB1, STAT3, TNP2, LBX2, SPO11, DMRT2, ZFP37, MSH4, MSH5, LTF, RB1, ACR, POLG, PMS2, KHDRBS1, ATR, SOHLH1, LIN28B, SYCP3, ESX1, EBF2, PARP2, PROP1, THRB, PCNA, H2AFX, NR2F2, APEX1, OTX1, PPARG, GATA4, SOX2, CDK9, XPC, MEF2A, EMX1, SOS1, FOXO1, H1FNT, HSFY1, MND1, ZNF331, CHD7, CLOCK, TOP2A, USF1, SOX5, ETV5, KDM5C, CREM, NR1H3, H2BFWT, TAF4B, MAEL, SIN3A, NPAS2, RHOXF2, KDM5D, TP63, TCF7L2, SOHLH2, GTF2A1L, SERPINA3, MYC, MYCN, TOP1, MPG, MSH2, AGFG1, TBPL1, HIST1H4A, FOXM1, SYCP1, ZNF174, TGIF2LY, TGIF2LX, PATZ1, ZNF230, YBX2, ETV2, ZNF646, ZBTB5, SHOX, HOXA3, XRCC2, HMGN1, GLI3, H1-4, MCM3, HOXD13, FUS, TCF7, HDAC |
| DNA binding domain binding | molecular function | PROX1 |
| DNA binding, bending | molecular function | SRY, TOP2A, HMGB3, HMGA2, HMGB1, LEF1, FOXI1, TRERF1, FOXC1, TFAM, HHEX, TREX1 |
| DNA clamp unloader activity | molecular function | ATAD5, RFC1 |
| DNA end binding | molecular function | XRCC5, NHEJ1 |
| DNA hairpin binding | molecular function | NR0B1 |
| DNA helicase activity | molecular function | MCM3, HELQ, MCM8, DDX3X, G3BP1, XRCC5, SUPV3L1, DHX36, ATRX, RECQL5, ERCC6, SETX, CHD1L, MCM9, RUVBL2, ASCC3, RECQL, ERCC8, XRCC6, NAV2, RTEL1, MRE11, CHD5, SMARCAL1, CHD9, MCM5, CHD4, ZRANB3, RUVBL1, FBH1, GTF2F2, RAD50, BLM, CHD6, MCM4, MCM7, SMARCAD1, MCM6, BRIP1, RECQL4, DDX11, CHD3, HELB, CHD8, IGHMBP2, MCM2, RAD54L2, RAD54B |
| DNA ligase (ATP) activity | molecular function | LIG4, PARP1, PARP2, LIG1, LIG3 |
| DNA ligase activity | molecular function | LIG4, XRCC1, LIG1, LIG3 |
| DNA N-glycosylase activity | molecular function | OGG1, MPG, NEIL1, RPS3, TDG, NEIL2, NTHL1, MUTYH, MBD4, SMUG1, NEIL3 |
| DNA nucleotidylexotransferase activity | molecular function | DNTT |
| DNA polymerase activity | molecular function | POLB, POLL, DNTT |
| DNA polymerase binding | molecular function | NCOA2, PCNA, PTGES3, SMARCA4, FANCD2, POLG2, RTEL1, HMGB1, SMG6, CDK2AP1, ACD, NABP2, LONP1, NAT10 |
| DNA polymerase processivity factor activity | molecular function | PCNA, POLG2, TEFM |
| DNA primase activity | molecular function | PRIM2, PRIM1, PRIMPOL |
| DNA replication origin binding | molecular function | HSPD1, MCM3, MCM8, ORC5, MCM9, ORC1, ORC3, CDC45, ORC2, CDC6, MCM5, ORC4, GRWD1, MCM4, MCM7, MCM6, DDX11, MCM10, MCM2, POLA1, MCMDC2 |
| DNA secondary structure binding | molecular function | CLSPN |
| DNA topoisomerase activity | molecular function | TOP2A, TOP1, TOP2B, TOP3B, TOP1MT |
| DNA topoisomerase binding | molecular function | NCAPH, NCL, TOPORS |
| DNA topoisomerase type I activity | molecular function | TOP1, TOP3B, TOP1MT |
| DNA topoisomerase type II (ATP-hydrolyzing) activity | molecular function | SPO11, TOP2A, TOP1, TOP2B |
| DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity | molecular function | NCAPH |
| DNA translocase activity | molecular function | ATRX, FBH1, RAD54B, RAD54L |
| DNA-(apurinic or apyrimidinic site) lyase activity | molecular function | OGG1, APEX1, NEIL1, HMCES, RPS3, APEX2, NEIL2, HMGA2, NTHL1, POLB, NEIL3, APLF |
| DNA-3-methyladenine glycosylase activity | molecular function | MPG |
| DNA-3-methylguanine glycosylase activity | molecular function | MPG |
| DNA-7-methyladenine glycosylase activity | molecular function | MPG |
| DNA-7-methylguanine glycosylase activity | molecular function | MPG |
| DNA-binding transcription activator activity | molecular function | E2F5, E2F4, E2F3, ZNF341 |
| DNA-binding transcription factor binding | molecular function | YAP1 |
| DNA-binding transcription factor inhibitor activity | molecular function | DDIT3, ID3, SMAD6, TAF1, ID4, ID2, MDFI, NCAPG2 |
| DNA-binding transcription repressor activity | molecular function | TCF7, HES1, YY1, SOX6, E2F7, E2F8 |
| DNA-dependent ATPase activity | molecular function | ERCC2, TOP2A, XRCC2, GTF2H3, DMC1, SMARCA2, CDK7, DHX36, RAD51C, SMARCA5, SMARCA4, TTF2, ERCC6, HLTF, ERCC8, MSH6, SMARCAL1, RBBP4, BTAF1, SMARCA1, GTF2H1, BPTF, ZRANB3, RAD51B, RAD51D, BLM, CHD6, SMARCAD1, DDX11, CHD8, INO80, XRCC3, IGHMBP2 |
| DNA-dependent protein kinase activity | molecular function | ATM, ATP23, PRKDC |
| DNA-directed 5'-3' RNA polymerase activity | molecular function | POLR1F, POLR1B, POLR1H, POLR2F, POLR3F, POLR2G, POLR1C, POLR1E, POLR2B, POLR3K, POLR2D, POLR1A, MED21, POLR1D, RPAP1, POLRMT, POLR3A, POLR3H, POLR2J, POLR2L, POLR2E, POLR2K, POLR2I, POLR3C, PRIM1, POLR2C, POLR3D, POLR2H, POLR3E, POLR2A, CRCP, PRIMPOL, POLR2M, POLR3B |
| DNA-directed DNA polymerase activity | molecular function | POLQ, POLG, REV1, REV3L, POLH, POLE3, POLK, POLG2, POLI, TENT4B, POLE4, CHRAC1, POLE, POLD4, POLB, POLL, POLD1, POLN, PRIMPOL, DNTT, POLA1 |
| DNA-methyltransferase activity | molecular function | MGMT, DNMT1, DNMT3B |
| DNA-N1-methyladenine dioxygenase activity | molecular function | ALKBH3 |
| DNA/DNA annealing activity | molecular function | ANXA1 |
| DNA/RNA helicase activity | molecular function | DDX1 |
| dodecanoyl-[acyl-carrier-protein] hydrolase activity | molecular function | OLAH |
| dodecenoyl-CoA delta-isomerase activity | molecular function | ECI2, ECI1 |
| dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity | molecular function | ALG3 |
| dolichol kinase activity | molecular function | DOLK |
| dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity | molecular function | ALG8 |
| dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity | molecular function | ALG10, ALG10B |
| dolichyl-phosphate beta-D-mannosyltransferase activity | molecular function | DPM1 |
| dolichyl-phosphate beta-glucosyltransferase activity | molecular function | ALG5 |
| dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity | molecular function | ALG8 |
| dolichyl-phosphate-mannose-protein mannosyltransferase activity | molecular function | TMTC2, SDF2L1, SDF2, TMTC1, TMTC4, POMT1, DPM1 |
| dopachrome isomerase activity | molecular function | MIF, DCT |
| dopamine beta-monooxygenase activity | molecular function | MOXD1, DBH |
| dopamine binding | molecular function | DRD3, TH, DRD1, DRD2, GPR143, SLC6A3, DRD4 |
| dopamine neurotransmitter receptor activity | molecular function | DRD3, DRD1, DRD2, DRD4 |
| dopamine neurotransmitter receptor activity, coupled via Gi/Go | molecular function | DRD3, DRD2, DRD4 |
| dopamine neurotransmitter receptor activity, coupled via Gs | molecular function | DRD1 |
| dopamine receptor binding | molecular function | SLC9A3R1 |
| dopamine:sodium symporter activity | molecular function | SLC6A2, SLC6A3, SLC22A1, SLC22A3 |
| double-strand/single-strand DNA junction binding | molecular function | MSH2, RBBP8 |
| double-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular function | APEX1, APEX2 |
| double-stranded DNA 5'-3' exodeoxyribonuclease activity | molecular function | EXO1 |
| double-stranded DNA binding | molecular function | NR5A2, EGFR, TP53, NR5A1, SP1, DNMT1, STAT1, CTNNB1, PARK7, USF1, TP63, MSH2, H1-4, HNRNPU, DMC1, RBBP8, KLF4, KIN, YBX3, CEBPG, ZNF638, MTERF1, POLR3F, XRCC5, RBMS1, FEN1, LSM14A, ZMPSTE24, PURA, APTX, HMGB3, AKAP8, PCBP3, JDP2, MNDA, FOSB, ZCCHC3, NFIB, YBX1, TEF, PCID2, REXO4, ERCC5, SP3, TDG, POLG2, XRCC6, LMNB1, TDP1, H1-2, ELK1, MSH6, NTHL1, HLF, MTERF3, MEN1, NFIC, HMGB1, MRE11, ASCL1, H1-8, CGGBP1, SATB1, NEUROD1, MAU2, HNRNPDL, PRKDC, CENPX, AIM2, ZMYND11, IFI16, CRY1, FBH1, PIN4, H1-0, SMAD2, MTERF2, RAD51B, FOS, CGAS, NKX2-8, PQBP1, H1-5, SAFB, DDX60, GTF2H4, PURG, AFF3, CDX2, H1-1, RAD51AP1, H1-3, ZBTB16, NEIL3, DDX11, JUND, MTERF4, CENPS, PURB, IMUP, TREX1, ZNF148, MCM10, SMAD3, PYHIN1, RFC1, HES2 |
| double-stranded DNA exodeoxyribonuclease activity | molecular function | APEX1, FEN1 |
| double-stranded DNA helicase activity | molecular function | ANXA1, CHD3 |
| double-stranded methylated DNA binding | molecular function | MBD1, EGR1, MECP2, MACROH2A1, ZNF445 |
| double-stranded RNA adenosine deaminase activity | molecular function | ADARB1, ADAR, ADAD2, ADARB2 |
| double-stranded RNA binding | molecular function | VIM, HSPD1, DROSHA, DICER1, HNRNPU, YRDC, DDX1, ADARB1, LRRFIP1, IFIH1, SUPV3L1, DHX36, AGO4, A1CF, OAS1, LSM14A, PRKRA, STAU1, ADAR, APTX, ILF2, DDX21, TFRC, EIF4A1, ZFR, ILF3, TARBP2, DHX58, AGO3, OASL, MBNL1, DHX15, ZBP1, RC3H2, TUBB4B, ADAD2, STAU2, ACTN1, MSN, RFTN1, RC3H1, DUS2, ZFR2, SIDT2, AGO2, CLTC, DHX30, SIDT1, EIF2AK2, DDX60, AGO1, MRPL44, TLR7, ADARB2, TLR3, SLC3A2, DHX33, OAS2, ZNF346 |
| double-stranded telomeric DNA binding | molecular function | APEX1, XRCC5, PURA, XRCC6, RAD50, HMBOX1, ZBTB48 |
| drug binding | molecular function | ACE, ESR2, NR1I2, ALB, GSTP1, IL2RA, ACR, CHKA, PPARG, TOP2A, ATP5PO, TYMS, CXCR4, RARB, UGT1A8, PPARD, PPP3CB, PNP, CHRNA2, NAMPT, CYP4B1, DCK, PGGT1B, HMGCS1, CHRM3, SMO, FASN, DHFR, CNR1, ATP1A2, LRP2, NPC1L1, PPP3CA, AOC1, SRP54, PDE4D, MT2A, NME2, DHODH, ATP1B1, PYGL, MT3, HTR2C, DRD3, HTR1B, TLR7, SIGMAR1, GABRA1, P2RX4, PDE2A, CHRNB2, CYP2D6, DRD2, PPARA, SLC6A3, FSCN1, DCAF15, CUBN, UGT1A7, DRD4, CHRNB4, RARA, CYP2C9, FOLR1, HTR2B, ATP4B |
| drug transmembrane transporter activity | molecular function | SLC22A18, SLC22A5 |
| drug:proton antiporter activity | molecular function | SLC22A18 |
| dTTP diphosphatase activity | molecular function | NUDT15, ITPA, ENPP3, ENPP1 |
| dTTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| dUTP diphosphatase activity | molecular function | DUT |
| dUTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| dynactin binding | molecular function | SNX6, SPTBN5, HOOK3, BICD1, BBS4, SNX5, BICD2, HTT, BICDL1 |
| dynein binding | molecular function | FMR1, KATNB1 |
| dynein complex binding | molecular function | KASH5, DNAAF1, GPSM2, RAB29, ATMIN, NEFH, SNCA, SMC3, BICD1, CENPF, APC, NUMA1, BICD2, CFAP73, TPR, HDAC6, CFAP100 |
| dynein heavy chain binding | molecular function | WDR63, TRIM58, DYNC2LI1, DYNC1I1, DYNC1I2, DNALI1, DYNC1LI2, DNAL1, DNAI2, WDR78, DYNC1LI1, WDR60, WDR34 |
| dynein intermediate chain binding | molecular function | DNAH6, DYNLRB1, DNAH2, DNAH17, DYNLRB2, SPTBN5, TRIM58, BAG3, HOOK3, BICD1, DNAH3, DNHD1, DNAL4, DNAH10, DNAH8, HTT, DYNLL2, DNAAF5, DNAH14, TCTEX1D2 |
| dynein light chain binding | molecular function | WDR63, DYNC1I1, DYNC1I2, HOOK3, GLUL, DNAI2, WDR78, WDR60, WDR34 |
| dynein light intermediate chain binding | molecular function | DYNC1H1, DNAH6, DNAH2, DNAH17, CCDC88B, CCDC88A, HOOK3, HOOK2, DNAH3, DNHD1, DNAL4, DNAH10, BICD2, DNAH8, CCDC88C, RILP, RILPL2, DYNLL2, RAB11FIP3, DNAH14, RILPL1 |
| dynorphin receptor activity | molecular function | OPRK1 |
| dystroglycan binding | molecular function | DMD, AGR2, AGR3, MAP2, VCL, CLASP2, DAG1, FKRP, AGRN, CLASP1 |
| E-box binding | molecular function | AHR, CLOCK, MYC, MAX, PER1, PSPC1, SFPQ, SREBF2, NEUROG2, HES1, ASCL2, NEUROG1, BHLHE40, MITF, GATA3, NONO, ASCL1, NEUROD1, TWIST1, ZEB1, TCF4, CRY1, NR1D1, LMO2, HES4, ARNTL, MYOD1, MYOG, MYBBP1A, SCRT2, TFAP4, HAND2, PTF1A, BHLHE41 |
| Edg-2 lysophosphatidic acid receptor binding | molecular function | RALA, GRK2 |
| efflux transmembrane transporter activity | molecular function | SLC22A2, SLC17A3, SLC27A1, ABCB5, ABCB6, XPR1, ABCC5, ABCC4, SLC26A6, ABCG2 |
| EH domain binding | molecular function | EPN3 |
| electron carrier activity | molecular function | CYP19A1, CYP1A2, GSR, SRD5A1, XDH, CYCS, MT-CO1, MT-CYB, SDHB, AKR1B1, HAAO, GLRX5, COX7A2L, NDUFS6, ADH5, GLDC, NDUFAF2, CYB5B, COX5A, ETFDH, TXNRD1, AOC2, DHRS3, CIAPIN1, AKR7A2, CYBB, COX7A2, COX11, AKR1A1, SH3BGRL3, LOXL2, NDUFS2, IDO1, ME1, GLRX2, POR, STEAP4, SDHD, GLRX3, FDX1, CYBA, NDUFS1, PTGES2, NDUFA12, HSD17B6, UQCR11, DEGS1, ETFB, IDH3B, NCF1, NDUFV2, ALDH2, DMGDH, QDPR, GPX2, PHGDH, ASPH, TSTA3, FDX2, CYC1, ETFA, SDHC, AOX1, ME2, ALDH4A1, GLRX, P4HA2, NQO2, COX7A1, AKR1C4, DHDH |
| electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity | molecular function | CYCS, CYC1 |
| electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity | molecular function | CYC1 |
| electron-transferring-flavoprotein dehydrogenase activity | molecular function | ETFDH |
| elongation factor-2 kinase activity | molecular function | EEF2K |
| endodeoxyribonuclease activity | molecular function | APEX1, RPS3, DNASE2B, ERCC5, MRE11, ZRANB3, MBD4, ERCC4, DNASE2, DNASE1L3, BIVM, APLF |
| endodeoxyribonuclease activity, producing 5'-phosphomonoesters | molecular function | TATDN1, ENDOV, TATDN2 |
| endogenous lipid antigen binding | molecular function | CD1C, CD1E |
| endonuclease activity | molecular function | RAG1, OGG1, ERCC1, PMS2, APEX1, DROSHA, DICER1, RNASET2, ANKLE1, RBBP8, FAN1, G3BP1, LACTB2, FEN1, ZC3H12A, N4BP2, SLX1A, RNASE11, CPSF3, RNASE4, ENDOV, DNASE2B, PELO, ELAC1, APEX2, MUS81, DCLRE1C, ELAC2, REXO4, AGO3, PXDNL, RNASE2, ERCC5, PPP1R8, ENDOG, EXO1, RNASEL, NTHL1, MRE11, SMG6, NOB1, YBEY, ERN1, TSN, ZRANB3, DIS3, AGO2, GEN1, ERCC4, RNASE6, RNASE3, RNASEH2A, DNASE2, DNASE1L3, MRPL44, ANG, DNASE1, ERN2, ZC3H12D, RNASEH1, SND1, EME2, DNASE1L1, PGBD5, RNASE7, EXOG |
| endopeptidase activator activity | molecular function | PSMD14, PSME1, ADRM1, SFRP2, VSIR |
| endopeptidase activity | molecular function | ACE, MMP9, CASP1, CASP6, KLK3, CD46, MMP12, ADAMTS20, ELANE, PSMA3, ACE2, PMPCB, PSMB1, PSMB5, PSMA8, PARL, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, TRAPPC12, UQCRC2, CPS1, APH1B, ZMPSTE24, CTSB, PSMB6, ECE1, CLPP, APH1A, F7, PSMB4, MBTPS1, MMEL1, TMEM59, IDE, PSMB8, ADAMTS9, PSMA6, CELA2A, PMPCA, PSEN1, CAPN7, PCSK2, PCSK6, HTRA4, TPP1, PSMB9, MMP14, RHBDD1, CPNE1, SENP1, ATG4B, PSMA4, TPP2, KLK13, PSMB3, MMP13, PIDD1, RCE1, PLG, MME, PCSK1, PSEN2, BACE1, KDM8, ADAMTS15, FURIN, ADAMTS13, TRABD2A, CTSH, GZMM, ADAMTS3, NAPSA, PREP, HTRA3, MMP8, PSMB10 |
| endopeptidase inhibitor activity | molecular function | C3, A2M, SPINK1, SLPI, USP14, TFPI, ITIH2, CSTB, SPINT2, C5, PROS1, SERPINF2, SMR3B, CSTA, CAST, PI3, PSMF1, WFDC2, CD109, UCHL5, CST7, HRG, RENBP, ITIH4, A2ML1, RECK, AHSG, ITIH3, SPP2, FETUB |
| endopeptidase regulator activity | molecular function | ABCA2 |
| endoplasmic reticulum signal peptide binding | molecular function | SRP14, SRP54 |
| endopolyphosphatase activity | molecular function | NUDT4, NUDT3 |
| endoribonuclease activity | molecular function | APEX1, DROSHA, DICER1, LACTB2, ZC3H12A, CPSF3, AGO3, ENDOG, RNASEL, SLFN11, SMG6, NOB1, YBEY, ERN1, TSN, KHNYN, AGO2, TSNAX, AGO1, RCL1, ERN2, ZC3H12D, SND1, EXOG |
| endoribonuclease activity, cleaving miRNA-paired mRNA | molecular function | AGO3, AGO2 |
| endoribonuclease activity, cleaving siRNA-paired mRNA | molecular function | AGO2 |
| endoribonuclease activity, producing 3'-phosphomonoesters | molecular function | RIDA |
| endoribonuclease activity, producing 5'-phosphomonoesters | molecular function | DICER1, ENDOV, ELAC1, AGO2 |
| endoribonuclease inhibitor activity | molecular function | TMBIM6 |
| endothelin A receptor binding | molecular function | EDN1 |
| endothelin B receptor binding | molecular function | EDN1, EDN3 |
| endothelin receptor activity | molecular function | EDNRA, EDNRB |
| enhancer binding | molecular function | AHR, SOX9 |
| enhancer sequence-specific DNA binding | molecular function | SOX9, GATA4 |
| enkephalin receptor activity | molecular function | OPRD1 |
| enoyl-CoA hydratase activity | molecular function | ECHS1, ECHDC2, AUH, HADHB, HADHA, ECHDC1, ECI1 |
| enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity | molecular function | FASN |
| enterobactin transmembrane transporter activity | molecular function | ASIC3 |
| enzyme activator activity | molecular function | DNMT3L, CASP9, ALOX5AP, DBF4, CYB5B, XRCC5, DTX3L, MGST2, PRKRA, SLX4, TAB1, PSAP, MMP15, DCP1B, DBNL, CLPS, CTSA, DDOST, CFLAR, MMP16, ARL1, RAB3GAP2, PRKCD, KRTCAP2, CXCL1, WRNIP1, PRKCE, LTC4S, APOA5, DCP1A, GMFB, SFRP2, DPM2, PPP1R12B, TRIM23, DAD1, GMFG, F2, MMP17, APOBEC1, PITRM1, SAE1, RFC1, GTF3C4, LRCOL1, GM2A |
| enzyme binding | molecular function | SOD1, EGFR, TGFB1, ESR1, TP53, CYP1A1, PGR, IL6R, AR, PTGS2, BRCA1, NR5A1, HIF1A, ESR2, DNMT3L, BIRC5, CYP1A2, GSTM1, HMOX1, CFTR, XRCC1, AKT1, STAT1, MDM2, ALB, APP, PARP1, ACAT1, CTNNB1, CBS, HSPA9, HSPA2, PTEN, PLAUR, PARK7, A2M, CAT, RB1, YES1, HSPA5, IGF2R, SRC, MAPK8, CABYR, HSPA1A, HSPA1B, THRB, PCNA, H2AFX, PPARG, CDC20, PICK1, CYB5A, TOP2A, ANK1, USF1, NPC2, TUBA4A, ECM1, TSPYL1, SLPI, MSH2, MAPK14, TEP1, PEX7, HSPA8, ATP2A2, COPS5, SELENOS, TSPAN10, TUT1, MCM8, TRAK2, PIAS1, PCCA, GLDC, COTL1, MLEC, CTNNBL1, PAWR, HACD1, RPA2, RFC4, CBX1, CBX3, PDCD2, WDR70, LGALS9, TULP3, BCL10, CAPN2, PMS1, BTG1, YWHAH, NCOA6, ANKMY2, DTX3L, HDAC2, SPDL1, BLZF1, UGT1A8, MAT2B, LUC7L2, PRKRA, VAPB, P4HB, RPS2, PRKCH, RFC5, RACK1, SUDS3, MARCHF7, ATXN10, DVL1, PPP1R3D, RPS3, PEBP1, TMBIM6, NOP14, SCARB2, NDUFAF7, LONP2, PHF6, MCM9, CASC3, PRKN, BCR, PPP3CB, RYR1, DHCR24, DYM, RYR2, HDHD2, MDM4, POR, ATF7, UGT1A4, TARBP2, RPS19BP1, NOXO1, BIRC7, KDM4C, ACIN1, STUB1, SUPT5H, DDC, CCND1, NOTCH1, PEX5, PARP14, NOXA1, NO |
| enzyme inhibitor activity | molecular function | TIMP1, CD46, NGF, TIMP2, PPP1R12A, TXNIP, DTX3L, UGT1A8, TIMP3, SLN, NOTCH1, SCG5, ATP5IF1, ANGPTL3, FRY, CCAR2, WDTC1, MRLN, PLN, PRPSAP1, CABP1, ANGPTL4, WFIKKN2, PDE6G, TIMP4, PPP1R12B, WFIKKN1, RENBP, LXN, PPP1R12C, UGT1A9, UGT1A7, PRPSAP2, FETUB |
| enzyme regulator activity | molecular function | DNMT3L, PSMD6, PPP1R7, RGN, PSMD1, CALML6, SLN, COX6A1, DCP1B, SCG5, CALM1, CALM2, CALM3, MTMR9, EFCAB11, PSMD2, RAB3GAP2, ATP6V1H, CALML4, DCP1A, CALML5, PSMD3, DPM2, CALML3, COX6A2, APOC3, CPN2 |
| EP4 subtype prostaglandin E2 receptor binding | molecular function | FEM1A |
| ephrin receptor activity | molecular function | EPHB2, EPHB1, EPHA6, EPHA4, EPHA1, EPHA2, EPHA7, EPHA3, EPHA8, EPHB3, EPHB4, EPHA10, EPHB6 |
| ephrin receptor binding | molecular function | SRC, CHN1, SHC1, NCK1, EFNA1, ANKS1A, EFNA5, CDK5R1, GRB2, ABL1, CBL, EFNA2, LYN, PTPN1, EPHA4, PIK3CG, EFNB1, EFNB2, EPHA7, CDK5, EFNB3, CRK, EFNA3, ANKS1B |
| epidermal growth factor binding | molecular function | SHC1, SEC61B, NRDC |
| epidermal growth factor receptor binding | molecular function | EGF, ITGA5, YES1, AREG, ARF4, SNX2, SHC1, SOCS5, TGFA, VAV3, SNX4, FAM83B, CCDC88A, AGR2, EREG, CNOT9, GRB2, PLSCR1, FER, CBL, VAV2, RNF126, MS4A1, HBEGF, BTC, CBLC, LINGO1, ATXN2, EFEMP1 |
| epidermal growth factor-activated receptor activity | molecular function | EGFR, EFEMP1 |
| epinephrine binding | molecular function | ADRB2, ADRB3, ADRA2A, ADRA2B, ADRB1, RNLS, ADRA2C, DRD4 |
| epoxide hydrolase activity | molecular function | EPHX2, LTA4H, RNPEP, EPHX4, EPHX1 |
| ER retention sequence binding | molecular function | KDELR2, KDELR3, CEMIP, KDELR1, KCNIP2 |
| ErbB-2 class receptor binding | molecular function | NRG1, ERBIN, MUC4, CDK5 |
| ErbB-3 class receptor binding | molecular function | ERBB2, NRG1, PIK3R1, ERBB3, CDK5 |
| erythropoietin receptor activity | molecular function | EPOR |
| erythropoietin receptor binding | molecular function | RNF41, EPO |
| estradiol 17-beta-dehydrogenase activity | molecular function | HSD17B1, HSD17B2, HSD17B7, HSD17B8, HSD17B14, HSD17B6, HSD17B11, HSD17B12, DHRS11, RDH8 |
| estradiol binding | molecular function | ESR2 |
| estrogen 16-alpha-hydroxylase activity | molecular function | CYP2C8, CYP3A5, CYP3A43 |
| estrogen receptor activity | molecular function | ESR1, ESR2, NKX3-1, LEF1, GPER1 |
| estrogen receptor binding | molecular function | NRIP1, DNMT1, CTNNB1, SRC, NCOA2, PCNA, PPARG, FUS, ISL1, CNOT1, NSD1, NCOA6, DCAF13, XBP1, NKX3-1, TACC1, PPARGC1A, DCAF1, PRMT2, PPID, DNAAF4, PHB2, PADI2, STRN, CCDC62, NCOA1, TRIP4, LATS1, PAGR1, TAF10, WIPI1, LEF1, ARID5A, MMS19, ZNF366, FOXL2, PPARGC1B, WBP2, DDX54, ESR1 |
| estrogen response element binding | molecular function | ESR1, ESR2, TRIM24 |
| estrone sulfotransferase activity | molecular function | SULT1E1, SULT2A1 |
| ethanol binding | molecular function | ADH4, PRKCE |
| ethanolamine kinase activity | molecular function | CHKA, ETNK2, ETNK1 |
| ethanolamine-phosphate cytidylyltransferase activity | molecular function | PCYT2 |
| ethanolaminephosphotransferase activity | molecular function | CEPT1, PIGF, SELENOI |
| ether hydrolase activity | molecular function | TMEM86B |
| euchromatin binding | molecular function | CTNNB1, ASH2L |
| eukaryotic initiation factor 4E binding | molecular function | DDX3X, EIF4EBP2, EIF4EBP1, C8orf88, LARP1, HHEX |
| eukaryotic initiation factor 4G binding | molecular function | EIF4E |
| eukaryotic initiation factor eIF2 binding | molecular function | NCK1, EIF5 |
| eukaryotic translation initiation factor 2alpha kinase activity | molecular function | EIF2AK1, EIF2AK2, EIF2AK3 |
| excitatory extracellular ligand-gated ion channel activity | molecular function | TRPV1 |
| exo-alpha-(2->3)-sialidase activity | molecular function | NEU1, NEU4, NEU2 |
| exo-alpha-(2->6)-sialidase activity | molecular function | NEU1, NEU4, NEU2 |
| exo-alpha-(2->8)-sialidase activity | molecular function | NEU1, NEU4, NEU2 |
| exo-alpha-sialidase activity | molecular function | GLB1, NEU1, NEU4, NEU2 |
| exodeoxyribonuclease I activity | molecular function | EXD2 |
| exodeoxyribonuclease III activity | molecular function | RAD9A, RAD1, TREX1 |
| exogenous lipid antigen binding | molecular function | CD1C, CD1E |
| exon-exon junction complex binding | molecular function | CPSF6 |
| exonuclease activity | molecular function | APEX1, EXOSC10, MEIOB, DDX1, FAN1, EXO5, FEN1, CNOT8, PARN, ERI2, ISG20, REXO2, AEN, PLD4, MGME1, XRN2, APEX2, REXO5, DCLRE1C, REXO4, PAN2, EXO1, TDP1, DXO, ENPP1, ERI1, REXO1, EXD3, DCLRE1B, MRE11, RAD9A, RAD1, XRN1, DIS3, PNPT1, ERI3, CNOT6L, TRIR, EXD2, DIS3L, DIS3L2, TREX1, POLD1, PLD3, ISG20L2 |
| exopeptidase activity | molecular function | ACE, GGH, MME, CPA1 |
| exopolyphosphatase activity | molecular function | BNIP2, BNIPL, PRUNE2, PRUNE1, ATCAY |
| exoribonuclease activity | molecular function | EXOSC10, ZC3H12A, EXOSC9, EXOSC7, EXOSC5, EXOSC1, EXOSC3, EXOSC8, EXOSC4, EXOSC6, DCPS, EXOSC2 |
| exoribonuclease activity, producing 5'-phosphomonoesters | molecular function | DCP2 |
| exoribonuclease II activity | molecular function | ISG20 |
| extracellular ligand-gated ion channel activity | molecular function | GABRB1, CHRNA5, GABRA2, CHRNE, HTR3B, HTR3A, CHRNA2, GABRG2, GABRB3, GLRA3, CHRNB1, GABRA5, CHRNA7, CHRND, CHRFAM7A, CHRNA10, GABRB2, GABRA4, GABRG1, CHRNA3, GABRP, GABRD, HTR3E, GLRA1, CHRNA6, GABRR2, CHRNG, GABRA1, CHRNB2, GABRA3, CHRNA4, ZACN, GABRQ, GABRR3, GABRG3, CHRNA1, GLRA2, CHRNB4, TRPV1 |
| extracellular matrix binding | molecular function | DCN, VEGFA, ADAMTS5, ITGAV, CCN1, COL11A1, CLEC14A, ITGA2B, SPP1, SPOCK2, THBS1, BGN, ITGB3, TGFBI, SPOCK1, VTN, ELN, ADAMTS15, SSC5D, CD248, FBLN2, OLFML2A, SMOC1, SPARCL1 |
| extracellular matrix constituent conferring elasticity | molecular function | LAMC1, FBN2, FBN1, FBLN5, EMILIN3, EMILIN1, MMRN1, ELN, FBLN2, EMILIN2 |
| extracellular matrix constituent, lubricant activity | molecular function | STATH, MUC4, MUC17 |
| extracellular matrix protein binding | molecular function | ITGAV, CLEC14A, ITGB8, CD248 |
| extracellular matrix structural constituent | molecular function | ANOS1, TFPI2, CCN1, COL11A1, LTBP2, COL5A2, LAMC1, TNXB, LTBP1, FBN2, MUC6, FBN1, MFAP4, COL9A3, MFAP2, SBSPON, COL3A1, COL4A1, COL11A2, COL8A1, MFAP5, CRELD1, MATN2, FGG, CHI3L1, ADIPOQ, FBN3, SRPX2, COL2A1, MFGE8, LAMA4, COL23A1, THBS1, COL4A2, LAMC2, UMOD, ACAN, COL9A1, FBLN1, PRELP, GP2, POSTN, IGFBP7, IMPG2, SPON1, MXRA5, FGB, COL4A6, BGN, SRPX, COL4A3, COL24A1, ABI3BP, FRAS1, COL1A2, FGL2, THSD4, MEGF9, EDIL3, TECTA, TNC, TGFBI, TINAGL1, EMILIN1, VTN, LAMB1, COL8A2, MMRN1, CD4, COL5A1, NID2, AEBP1, COL27A1, MATN3, FGA, MGP, COL5A3, COL18A1, LAMB3, PXDN, CILP, ELN, COL15A1, LAMA3, LAMA5, COMP, COL16A1, COL9A2, COL19A1, CTHRC1, COL17A1, AGRN, EFEMP2, FBLN2, PCOLCE, COL22A1, THBS2, THBS3, COL4A4, COL13A1, VWA1, LTBP4, COL28A1, DPT, ZP3, EFEMP1 |
| extracellular matrix structural constituent conferring compression resistance | molecular function | ASPN, ACAN, PRELP, BGN, HAPLN1, HSPG2, PRG2, PRG4, PODN, CHADL, OGN |
| extracellular matrix structural constituent conferring tensile strength | molecular function | COL11A1, COL5A2, COL9A3, COL12A1, COL3A1, COL4A1, COL11A2, COL8A1, COL7A1, COL2A1, COL23A1, COL4A2, COL9A1, COL4A6, COL4A3, COL24A1, COL1A2, COL6A1, COL6A6, COL21A1, COL8A2, COL6A2, COL5A1, COL27A1, COL5A3, COL18A1, COL15A1, COL6A3, COL16A1, COL9A2, COL19A1, COL17A1, COL4A4, COL13A1, COL6A5, COL28A1, COL25A1 |
| extracellularly ATP-gated cation channel activity | molecular function | P2RX7, P2RX6, P2RX4, P2RX5, P2RX3, P2RX2 |
| extracellularly glutamate-gated chloride channel activity | molecular function | SLC17A7 |
| extracellularly glutamate-gated ion channel activity | molecular function | GRIK2 |
| extracellularly glycine-gated chloride channel activity | molecular function | GLRA3, GLRA1, GLRA2 |
| extracellularly glycine-gated ion channel activity | molecular function | GLRA1 |
| F-box domain binding | molecular function | SKP1, PRKN |
| FAD binding | molecular function | MTRR, DAO, D2HGDH, AGPS, DHCR24, QSOX1, STEAP4, PRODH2, ACOX3, AIFM1, SQLE, MICAL3, CYB5R2, CYB5R3, LDHD, SQOR, AOX1, DDO, MICAL2, NQO2, MICAL1, MMACHC, CRY2, ACOX2, ACOX1, KDM1B, COQ6 |
| FAD transmembrane transporter activity | molecular function | SLC25A17, SLC25A32 |
| FAD-AMP lyase (cyclizing) activity | molecular function | TKFC |
| farnesyl-diphosphate farnesyltransferase activity | molecular function | FDFT1 |
| farnesylated protein binding | molecular function | AIPL1 |
| farnesyltranstransferase activity | molecular function | COX10 |
| Fas-activated serine/threonine kinase activity | molecular function | FASTK |
| FAT10 activating enzyme activity | molecular function | UBA6 |
| fatty acid alpha-hydroxylase activity | molecular function | FA2H |
| fatty acid amide hydrolase activity | molecular function | FAAH2, NAAA, FAAH |
| fatty acid binding | molecular function | ALB, PTGDS, ADH5, UGT1A8, SNCA, PPARD, FABP5, FABP3, GSTA1, PMP2, ACOX3, NDUFAB1, APOC1, NME2, HNF4A, ACOX2, ACOX1, CYP4F11, ACOXL |
| fatty acid elongase activity | molecular function | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| fatty acid ligase activity | molecular function | ACSM2A, ACSM5, ACSM3, ACSM1 |
| fatty acid peroxidase activity | molecular function | CYGB |
| fatty acid synthase activity | molecular function | MCAT, FASN |
| fatty acid transmembrane transporter activity | molecular function | SLC27A5, SLC27A1, MFSD2A, SLC27A2 |
| fatty-acyl-CoA binding | molecular function | ACBD3, SCP2, DBI, ACAD9, ECI2, GCDH, HADHA, ALDH6A1, SOAT1, ACADVL, ACADL, ACOT7, ACBD5, HMGCL, ACBD6, ACOT11, ACBD4 |
| fatty-acyl-CoA reductase (alcohol-forming) activity | molecular function | FAR1, FAR2 |
| fatty-acyl-CoA synthase activity | molecular function | ACSM2A, ACSM5, ACSM3, ACSM1 |
| FATZ binding | molecular function | TCAP, ACTN2, MYOZ1, MYOZ2 |
| FBXO family protein binding | molecular function | BIRC2, CDK6 |
| Fc-gamma receptor I complex binding | molecular function | FGR |
| ferric iron binding | molecular function | TF, FXN, FTL, RRM2, FTH1, FTMT, TH, FTHL17 |
| ferric iron transmembrane transporter activity | molecular function | TF |
| ferric-chelate reductase (NADPH) activity | molecular function | STEAP4, STEAP2, STEAP3 |
| ferric-chelate reductase activity | molecular function | CYB561, CYBRD1 |
| ferritin receptor activity | molecular function | SCARA5 |
| ferrochelatase activity | molecular function | FECH |
| ferrous iron binding | molecular function | PLOD1, TF, HAAO, FXN, FTL, FECH, SNCA, FTH1, PHYH, DNAJC24, CDO1, FTMT, HEPH, ISCU, EGLN1, HIF1AN, ALKBH3, TH, EGLN2, ALKBH1, TET2, FTHL17 |
| ferrous iron transmembrane transporter activity | molecular function | MMGT1, SLC40A1, SLC39A14 |
| ferroxidase activity | molecular function | FXN, FTH1, FTMT, HEPH, HEPHL1, FTHL17 |
| FFAT motif binding | molecular function | VAPB, VAPA, MOSPD3 |
| FHA domain binding | molecular function | MDC1 |
| fibrinogen binding | molecular function | ITGA2B, THBS1, FBLN1, CDH5 |
| fibroblast growth factor binding | molecular function | FGFR2, FGFR3, FGFR1, HSPA9, TGFBR3, ITGAV, CEP57, FGFBP3, RPS2, RPS19, THBS1, ITGB3, GLG1, API5, FIBP, FGFBP1, GPC1, KL, FGFR4, SCN5A, S100A13 |
| fibroblast growth factor receptor binding | molecular function | FGF17, FGF8, FLRT3, FGF3, FGF9, FGF12, FLRT1, FGF23, FLRT2, FGF5, FGF20, FRS2, FGF18, FGF22, FGF7, FRS3, FGF19, FGF21, FGF2, KL, FGF1, FGF14, FGF10 |
| fibroblast growth factor-activated receptor activity | molecular function | FGFR2, FGFR3, FGFR1, FGFR4 |
| fibronectin binding | molecular function | VEGFA, ITGB1, ITGAV, ITGA4, CCN2, CTSK, CTSL, SDC4, FSTL3, THBS1, FBLN1, ITGB3, PLEKHA2, CTSS, SFRP2, LOXL3, HSD17B12, SSC5D, IGFBP5, ITGA3, IGFBP6, MYOC |
| filamin binding | molecular function | RFLNB, DPYSL3, SYNPO2, NEBL, TMEM67, FBLIM1, CEACAM1, DPYSL4, CRMP1, MICALL2, RFLNA |
| first spliceosomal transesterification activity | molecular function | RBMX2 |
| FK506 binding | molecular function | FKBP4, FKBPL, FKBP6, FKBP5, NFATC1, FKBP10, FKBP3, FKBP1B, FKBP2 |
| flap endonuclease activity | molecular function | FEN1, EXO1, GEN1 |
| flap-structured DNA binding | molecular function | RBBP8, FAN1 |
| flavin adenine dinucleotide binding | molecular function | NOS3, MTHFR, MTRR, GSR, NOS2, XDH, PPOX, SDHA, NOX5, ACADM, ETFDH, TXNRD1, ACAD11, D2HGDH, AGPS, CYBB, ACAD9, IVD, DHCR24, ILVBL, POR, ACAD10, ACOX3, AIFM1, GCDH, FMO3, SQLE, DUS1L, MTO1, ACADVL, ACADL, DUS2, ACADSB, CYB5R3, NDOR1, ETFA, LDHD, AOX1, DPYD, ACAD8, FMO4, AIFM3, ACADS, FOXRED2, DUS3L, ACOX2, TXNRD2, ACOX1, KDM1B, GFER, FMO1, ACOXL, COQ6 |
| flavin-linked sulfhydryl oxidase activity | molecular function | QSOX1, QSOX2, GFER |
| flavonoid 3'-monooxygenase activity | molecular function | CYP1A1 |
| flavonoid binding | molecular function | IP6K2, IPMK |
| flavonol 3-sulfotransferase activity | molecular function | SULT1E1, SULT1A1, SULT1A2 |
| flippase activity | molecular function | ABCA4, ATP8A1 |
| floppase activity | molecular function | ABCG1, ABCA7 |
| fluorene oxygenase activity | molecular function | CYP4B1 |
| FMN adenylyltransferase activity | molecular function | FLAD1 |
| FMN binding | molecular function | NOS3, MTRR, NOS2, POR, DUS2, HAO2, NDOR1, DHODH, TYW1B, IYD, TYW1, PNPO, HAO1 |
| FMN transmembrane transporter activity | molecular function | SLC25A17 |
| folic acid binding | molecular function | SLC19A1, TYMS, GNMT, FTCD, MTHFS, DHFR, FOLR3, FOLR1 |
| folic acid receptor activity | molecular function | FOLR1 |
| folic acid transporter activity | molecular function | SLC19A1, SLC19A2, PDPN, SLC25A32 |
| follicle-stimulating hormone activity | molecular function | FSHB |
| follicle-stimulating hormone receptor activity | molecular function | FSHR |
| follicle-stimulating hormone receptor binding | molecular function | ARRB2 |
| forked DNA-dependent helicase activity | molecular function | BLM |
| formaldehyde dehydrogenase activity | molecular function | ADH5 |
| formate efflux transmembrane transporter activity | molecular function | SLC26A6 |
| formate transmembrane transporter activity | molecular function | SLC26A6 |
| formate-tetrahydrofolate ligase activity | molecular function | MTHFD1, MTHFD1L |
| formimidoyltetrahydrofolate cyclodeaminase activity | molecular function | FTCD |
| formimidoyltransferase activity | molecular function | FTCD |
| Formylglycine-generating oxidase activity | molecular function | SUMF1 |
| formyltetrahydrofolate dehydrogenase activity | molecular function | ALDH1L1, ALDH1L2 |
| four-way junction DNA binding | molecular function | MSH2, XRCC2, RAD51C, HMGB3, MSH6, MEN1, HMGB1, YY1, ABL1, GEN1, RAD51B, RAD51D, BLM, XRCC3 |
| four-way junction helicase activity | molecular function | RECQL5, RECQL, BLM, RECQL4 |
| frizzled binding | molecular function | RYK, NDP, BAMBI, DVL1, WNT10A, WNT7B, WNT4, WNT9B, WNT3A, RNF43, WNT2B, WNT8B, FZD7, LRP6, SDCBP, DVL2, CCDC88C, RSPO3, WNT11, DVL3, WNT10B, CTHRC1, ROR2, WNT9A, WNT3, ZNRF3, FZD1, WNT6, WNT7A, WNT5B, MYOC, WNT16 |
| fructokinase activity | molecular function | HKDC1, HK2, GCK, HK3 |
| fructosamine-3-kinase activity | molecular function | FN3K |
| fructose 1,6-bisphosphate 1-phosphatase activity | molecular function | FBP1, FBP2 |
| fructose binding | molecular function | SLC2A5, PFKM, ALDOB, ALDOA, PFKL |
| fructose transmembrane transporter activity | molecular function | SLC2A5, SLC2A8, SLC2A6, SLC2A7 |
| fructose-1-phosphate aldolase activity | molecular function | ALDOB |
| fructose-2,6-bisphosphate 2-phosphatase activity | molecular function | PFKFB2, PFKFB4, TIGAR |
| fructose-6-phosphate binding | molecular function | PFKM, PFKP, PFKL |
| fructose-bisphosphate aldolase activity | molecular function | ALDOB, ALDOA, ALDOC |
| fucokinase activity | molecular function | FCSK |
| fucose binding | molecular function | ACR, FUOM, COLEC11, SELP |
| fucose transmembrane transporter activity | molecular function | SLC5A1 |
| fucosylgalactoside 3-alpha-galactosyltransferase activity | molecular function | ABO |
| fucosyltransferase activity | molecular function | FUT4, FUT6, FUT5, POFUT2, FUT9, FUT7, FUT3, POFUT1, FUT2 |
| fumarate hydratase activity | molecular function | FH |
| fumarylacetoacetase activity | molecular function | FAH |
| fumarylpyruvate hydrolase activity | molecular function | FAHD1 |
| G protein-coupled acetylcholine receptor activity | molecular function | CHRM3, HRH4, HRH3, CHRM4, CHRM1, CHRM5, CHRM2 |
| G protein-coupled adenosine receptor activity | molecular function | P2RY12, ADORA3, ADORA2B, ADORA2A |
| G protein-coupled ADP receptor activity | molecular function | P2RY12, P2RY1, P2RY6 |
| G protein-coupled ATP receptor activity | molecular function | P2RY11, P2RY1 |
| G protein-coupled bile acid receptor activity | molecular function | GPBAR1 |
| G protein-coupled GABA receptor activity | molecular function | GABBR1, GPR156 |
| G protein-coupled glutamate receptor binding | molecular function | HOMER2, HOMER1, HOMER3 |
| G protein-coupled neurotensin receptor activity | molecular function | NTSR2, NTSR1 |
| G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular function | GRM1 |
| G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | molecular function | GABBR1, ADRB1 |
| G protein-coupled photoreceptor activity | molecular function | OPN5, ELOVL4, GNAT2, GPR88, RHO, OPN4, OPN3 |
| G protein-coupled purinergic nucleotide receptor activity | molecular function | P2RY4, GPR171, GPR34, P2RY12, P2RY1, P2RY14, PTAFR, P2RY2, P2RY6 |
| G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential | molecular function | GRM5, GRM1 |
| G protein-coupled receptor kinase activity | molecular function | GRK5, GRK4, GRK2, GRK3, GRK6, GRK7, GRK1 |
| G protein-coupled serotonin receptor activity | molecular function | HRH1, HTR7, CHRM3, HTR1E, HRH4, HTR2C, OR10H1, HTR1B, HRH3, CHRM4, CHRM1, CHRM5, HRH2, HTR5A, OR10H2, CHRM2, HTR6, DRD4, HTR2B, OR5T2 |
| G protein-coupled UDP receptor activity | molecular function | P2RY14, P2RY6 |
| G protein-coupled UTP receptor activity | molecular function | P2RY4, P2RY6 |
| G-protein activated inward rectifier potassium channel activity | molecular function | KCNJ9 |
| G-protein alpha-subunit binding | molecular function | IGF2R, F2R, GPSM2, NUCB2, CCDC88A, RIC8B, RGS2, RGS10, ADGRV1, CCDC88C, RGS1, SASH1, PPP5C, LPAR1, RGS19, GAS2L2, LPAR3, RGS14, RIC8A, NUCB1, PLCD4, RGS4, HTR2B |
| G-protein beta-subunit binding | molecular function | F2R, CCT5, GNG7, RASD2, RGS11, GNGT1, GNG10, GNG4, GNG2, GNG3, GNG11, GNG5, GNG8, GNG12, RGS7, GNG13, GNGT2 |
| G-protein beta/gamma-subunit complex binding | molecular function | GNAS, GNAO1, GNAI1, CETN2, GNAI2, CETN1, GNAI3, GNAZ, GNAT2, GNAL, GNA12, GNA11, GNAQ, GNA14, GNA15, PIK3R5 |
| G-protein coupled peptide receptor activity | molecular function | LHCGR, FSHR, KISS1R, LGR4, CYSLTR1, GPR37L1, PTH1R, CALCRL, RXFP1, NMBR, GIPR, GHRHR, MCHR2, NPR3, GCGR, LTB4R, BRS3, GLP1R, CX3CR1, CRHR1, CRHR2, UTS2R, NPR1, PTH2R, GLP2R, TSHR, ADCYAP1R1, GALR1, SCTR, RXFP4, GPR84, LGR5, CALCR, LTB4R2, GALR3, VIPR2, MC1R |
| G-protein coupled receptor activity | molecular function | LHCGR, FSHR, RXFP2, EDNRA, GNRHR, IGF2R, FPR1, GPRC6A, PROKR2, KISS1R, F2R, TACR3, OXTR, CCR5, TAS2R38, OR2W3, MAS1, P2RY4, OR12D2, VN1R2, LPAR4, ACKR4, GPR160, OR2AG2, LANCL1, CXCR4, GRM3, GRM4, F2RL3, FZD9, CCR1, GPR183, OR10AD1, OR5AR1, OR52D1, OR5V1, ADGRL1, BDKRB2, OR9A4, OR51A7, P2RY11, ADGRA2, LGR4, FZD8, GPR83, TAS2R9, FZD4, CYSLTR1, GPR171, GPR37L1, OR1G1, PTH1R, CALCRL, OR9Q2, OR51V1, HRH1, XCR1, TAS2R19, MC2R, TAS1R2, OR52A1, GPR45, LPAR6, OPN5, OR1L6, GPR119, HCAR1, RXFP1, GRM8, CCKAR, PRLHR, TAS2R50, FZD2, OR1N2, OR6B3, GHSR, TAAR6, HCRTR1, NPY, S1PR1, NMBR, OR10J1, HTR7, OR1D5, OR10A3, OR2T33, OR52E4, OR2H1, FZD3, GPR25, OR2J2, ADRB2, ADRB3, CXCR5, PTGER2, MTNR1A, OR56A4, OR10Q1, OR13C4, OR2T4, OR4X1, OR5P2, QRFPR, OR2M4, OR4C12, GPR34, OR5B21, OR5F1, ACKR3, AGTR1, PTGER1, GIPR, TAS2R60, GPR85, GHRHR, OR5I1, OR2L13, MCHR2, TM2D1, P2RY12, TAS2R8, GPR132, FZD7, ADRA2A, CHRM3, CXCR2, FPR3, ADRA1A, GPR4, GCGR, CCR6, ADGRF1, ADGRA3, ADGRF4, OR4D11, OR8D4, OR13A1, OR13C8, OR5R1, OR5K1, OR52B2, GPR22, |
| G-protein coupled receptor binding | molecular function | INSL3, GHRL, GNAI1, HSPA1A, HSPA1B, PROK2, PICK1, PACRG, SAA1, PROK1, HSPA8, TULP3, GNAI2, ARHGEF11, PRKN, GNAI3, GNAZ, STUB1, NPY, PSAP, GNAT2, S1PR1, UTS2B, MARCO, CORT, ARHGEF12, UCN, USP33, GNAL, ITGB4, GNA12, GNA11, GPRASP2, SAG, GNAQ, FCN1, S1PR2, NPFF, GNA14, ARHGEF1, GPRC5B, NPB, GNA15, SCT, UCN2, USP20, POMC, ARRB2, PYY, TUB |
| G-protein coupled serotonin receptor binding | molecular function | GNAO1, GNAI1, GNAI3, GNAZ |
| G-protein gamma-subunit binding | molecular function | GNB3, GNB5, GNB1, GNB4, CCDC88A, GNB2 |
| G-quadruplex DNA binding | molecular function | DHX36, XRN1, NME2, RAD50, BLM, DDX11, LONP1 |
| G-quadruplex RNA binding | molecular function | FMR1, DHX36, AFF2, XRN1, MCRS1, LIN28A |
| G-rich single-stranded DNA binding | molecular function | POT1 |
| G-rich strand telomeric DNA binding | molecular function | TERF2IP, HNRNPA1, RPA2, HNRNPA2B1, RPA1, POT1, NABP2 |
| G/U mismatch-specific uracil-DNA glycosylase activity | molecular function | TDG |
| GABA receptor binding | molecular function | GABRB1, TRAK2, PPP2CA, ARFGEF2, PLCL1, GABRA5, TRAK1, GABRG1, LHFPL4, GABARAPL1, GABARAP, GABARAPL2, MAF1, AKAP5, SHISA7, PLCL2 |
| GABA-A receptor activity | molecular function | GABRB1, GABRA2, GABRG2, GABRB3, GABRA5, GABRB2, GABRA4, GABRG1, GABRP, GABRD, GABRR2, GABRA1, GABRA3, GABRQ, GABRR3, GABRG3 |
| GABA-gated chloride ion channel activity | molecular function | GABRB1, GABRA2, GABRG2, GABRB3, GABRA5, GABRB2, GABRA4, GABRG1, GABRA1, GABRA3, GABRG3 |
| GAF domain binding | molecular function | AIP |
| galactokinase activity | molecular function | GALK2, GALK1 |
| galactolipase activity | molecular function | PNLIPRP2 |
| galactose 3-O-sulfotransferase activity | molecular function | GAL3ST3, GAL3ST2, GAL3ST4 |
| galactose binding | molecular function | LGALS9, COLEC12, GALK2, ENG, GALK1 |
| galactose transmembrane transporter activity | molecular function | SLC5A1 |
| galactoside 2-alpha-L-fucosyltransferase activity | molecular function | FUT2 |
| galactoside binding | molecular function | GLB1, GLA, LGALS9, LGALS2, LGALS4, LGALS9B |
| galactosylceramidase activity | molecular function | GALC |
| galactosylceramide sulfotransferase activity | molecular function | GAL3ST3, GAL3ST2, GAL3ST4 |
| galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity | molecular function | B3GALNT1 |
| galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity | molecular function | B3GAT1, B3GAT2, B3GAT3 |
| galactosyltransferase activity | molecular function | B4GALT2, B4GALT4, B4GALT3, B3GALT6, A4GALT, B4GALT6, B4GALT1, B4GALT5, B3GNT6 |
| galactosylxylosylprotein 3-beta-galactosyltransferase activity | molecular function | B3GALT6 |
| galanin receptor activity | molecular function | CYSLTR1, LTB4R, GALR1, GAL, LTB4R2, GALR3 |
| galanin receptor binding | molecular function | GAL |
| gamma-aminobutyric acid transmembrane transporter activity | molecular function | SLC6A6, SLC9A3R1 |
| gamma-aminobutyric acid:proton symporter activity | molecular function | SLC32A1 |
| gamma-aminobutyric acid:sodium symporter activity | molecular function | SLC6A6, SLC6A11, SLC6A12, SLC6A13 |
| gamma-catenin binding | molecular function | CDH1, TCF7L2, PTPRJ, CTNNA1, PTPRT, DSG1, APC, LEF1, DSC3, APC2 |
| gamma-glutamyl-peptidase activity | molecular function | GGH |
| gamma-glutamylcyclotransferase activity | molecular function | GGCT, CHAC1 |
| gamma-tubulin binding | molecular function | BRCA2, OFD1, BLOC1S2, CEP57, TUBGCP4, DDX3X, CEP70, NDN, RAB11FIP5, CDK5RAP2, FEZ1, CEP57L1, TUBGCP3, PDE4B, LYN, PIFO, RAD51D, TUBGCP5, NDRG1, TUBGCP2, NME1, TUBGCP6, BRSK1, MARK4, B9D2, DIXDC1 |
| ganglioside binding | molecular function | CLIP3 |
| ganglioside GM1 binding | molecular function | RTN4R, PSAP |
| ganglioside GM2 binding | molecular function | PSAP |
| ganglioside GM3 binding | molecular function | PSAP |
| ganglioside GP1c binding | molecular function | PSAP |
| ganglioside GT1b binding | molecular function | RTN4R, PSAP, MAG |
| gap junction channel activity | molecular function | GJA1, GJC2, GJD2, GJB1, PANX1, GJB3, GJB5, GJD4, GJA3, GJA5, GJA4, GJB6, GJB4, GJD3, GJC1, GJA9 |
| gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling | molecular function | GJA5 |
| gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling | molecular function | GJA5, GJC1 |
| gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling | molecular function | GJA5 |
| gap junction channel activity involved in cardiac conduction electrical coupling | molecular function | GJA1, GJA5, GJD3 |
| gap junction channel activity involved in cell communication by electrical coupling | molecular function | GJA1, GJC2, GJB6 |
| gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling | molecular function | GJA5 |
| gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling | molecular function | GJA5, GJC1 |
| GARP complex binding | molecular function | UHRF1BP1L |
| gastric inhibitory peptide receptor activity | molecular function | GIPR |
| GBD domain binding | molecular function | RHOQ |
| GDP binding | molecular function | GNAI1, 41153, DIRAS3, RAB9A, RAB18, RAB21, RIT1, ARL8B, RAB29, RAP2B, RAB27A, RALA, RAB2A, KRAS, RAB4A, ARL2, GNAI3, RRAS, RAB5A, ARL3, RAB31, RAB8B, GEM, ARF1, RAB35, RAB22A, RAB27B, SUCLG2, RIT2, RRAS2, RAB3B, RAB14, RAB7A, RALB, RAN, RHEB, RAB11B, GBP1, RAB28, RAB40C, MIEF1, DYNC1LI1, SRP54, RASEF, NME2, DIRAS2, RRAGD, RAB42, RAB5B, DIRAS1, HRAS, RAP2A, TRIM23, RAB5C, RAB8A, RAB17, MRAS, RAP1B, RHEBL1, RAB9B |
| GDP-4-dehydro-D-rhamnose reductase activity | molecular function | TSTA3 |
| GDP-dissociation inhibitor activity | molecular function | GPSM2, SH3BP4, GDI2, CHML, CCDC88A, GPSM1, EIF5, ITGB1BP1, ARHGDIG, SESN2, RGS14, GDI1 |
| GDP-fucose transmembrane transporter activity | molecular function | TMEM241, SLC35C1 |
| GDP-L-fucose synthase activity | molecular function | TSTA3 |
| GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity | molecular function | ALG2 |
| GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity | molecular function | ALG2 |
| GDP-mannose 3,5-epimerase activity | molecular function | TSTA3 |
| GDP-mannose 4,6-dehydratase activity | molecular function | GMDS |
| geranial:oxygen oxidoreductase activity | molecular function | AOX1 |
| geranylgeranyl reductase activity | molecular function | AKR1C3, AKR1B10 |
| ghrelin receptor binding | molecular function | GHRL |
| glial cell-derived neurotrophic factor receptor activity | molecular function | GFRA1, GFRA3, GFRA2, GFRA4 |
| glial cell-derived neurotrophic factor receptor binding | molecular function | NRTN, PSPN |
| glucagon receptor activity | molecular function | GCGR, GLP1R, GLP2R |
| glucagon-like peptide 1 receptor activity | molecular function | GLP1R |
| glucan 1,4-alpha-glucosidase activity | molecular function | MGAM, MGAM2 |
| glucocorticoid receptor activity | molecular function | NR3C1 |
| glucocorticoid receptor binding | molecular function | NRIP1, FKBP4, STAT3, NCOA2, YWHAH, STAT5B, TACC1, GRIP1, NR4A2, NCOR2, NR4A3, NR4A1, SMAD3, ETS2 |
| glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity | molecular function | NR3C1 |
| glucokinase activity | molecular function | HKDC1, HK2, GCK, HK3 |
| gluconokinase activity | molecular function | IDNK |
| gluconolactonase activity | molecular function | RGN |
| glucosamine 6-phosphate N-acetyltransferase activity | molecular function | GNPNAT1 |
| glucosamine-6-phosphate deaminase activity | molecular function | GNPDA1, GNPDA2 |
| glucosaminyl-phosphatidylinositol O-acyltransferase activity | molecular function | PIGW |
| glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity | molecular function | B3GALT2, B3GALT1 |
| glucose 1-dehydrogenase [NAD(P)] activity | molecular function | H6PD |
| glucose binding | molecular function | G6PD, UGP2, SLC2A3, HKDC1, SLC2A8, HK2, PYGL, GYS1, GCK, HK3 |
| glucose transmembrane transporter activity | molecular function | SLC2A5, SLC2A3, MFSD4B, SLC2A14, SLC2A8, SLC2A11, SLC2A4, SLC5A1, PPBP, SLC2A6, SLC2A7, MFSD4A |
| glucose-1,6-bisphosphate synthase activity | molecular function | PGM2L1 |
| glucose-6-phosphatase activity | molecular function | G6PC3, G6PC2 |
| glucose-6-phosphate dehydrogenase activity | molecular function | G6PD, H6PD |
| glucose-6-phosphate isomerase activity | molecular function | GPI |
| glucose-6-phosphate transmembrane transporter activity | molecular function | SLC37A4 |
| glucose:sodium symporter activity | molecular function | SLC5A1, SLC5A2, SLC5A10, SLC5A9 |
| glucoside transmembrane transporter activity | molecular function | SLC50A1 |
| glucosylceramidase activity | molecular function | GBA, GBA2 |
| glucosyltransferase activity | molecular function | POGLUT3, GBA2, POGLUT1 |
| glucuronolactone reductase activity | molecular function | AKR1A1 |
| glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | CSGALNACT1, CHSY1, CHSY3, CHPF |
| glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | molecular function | EXT1, EXTL1, EXT2 |
| glucuronosyltransferase activity | molecular function | B4GAT1, UGT2B7, UGT2B10, EXT1, CSGALNACT1, UGT1A8, LARGE2, UGT2B11, EXTL1, UGT1A4, UGT2B28, LARGE1, UGT2B15, UGT2B4, UGT2A3, EXT2, UGT2B17, UGT3A1, B3GAT3, UGT2A1, UGT1A9, UGT1A6, UGT1A3, UGT1A5, UGT1A7, UGT1A10 |
| glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity | molecular function | EXTL2, EXTL3 |
| glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | CSGALNACT1, EXTL2, CSGALNACT2 |
| glutamate 5-kinase activity | molecular function | ALDH18A1 |
| glutamate binding | molecular function | CPS1, GRIN1, GCLC, SLC1A3, GAD1, GLUL, GRIN2B, CEP104, GRM7, GAD2 |
| glutamate decarboxylase activity | molecular function | GAD1, GAD2 |
| glutamate dehydrogenase (NAD+) activity | molecular function | GLUD1, GLUD2 |
| glutamate dehydrogenase [NAD(P)+] activity | molecular function | GLUD1, GLUD2 |
| glutamate formimidoyltransferase activity | molecular function | FTCD |
| glutamate receptor activity | molecular function | GRM3, GRM4, GRM8, GRIA2, GRIN2C, GRIK3, GRIK5, GRIN2B, GRM2, GRIN3A, GRM6, GRID2, GRIA3, GRIK4, GRIN2A, GRIN3B, GRIA1, GRID1, GRIN2D, GRIK1, GRM5, GRIK2, GRM7, GRM1 |
| glutamate receptor binding | molecular function | HOMER2, SYNDIG1, AKAP5, RASGRF1, GRIP2, CAMK2A |
| glutamate-5-semialdehyde dehydrogenase activity | molecular function | ALDH18A1 |
| glutamate-ammonia ligase activity | molecular function | GLUL |
| glutamate-cysteine ligase activity | molecular function | GCLC |
| glutamate-gated calcium ion channel activity | molecular function | GRIN1, GRIN2C, GRIN2B, GRIN2A, GRIN2D |
| glutamate-tRNA ligase activity | molecular function | EPRS1, EARS2 |
| glutamate-tRNA(Gln) ligase activity | molecular function | EARS2 |
| glutamate:sodium symporter activity | molecular function | SLC1A2, SLC1A3 |
| glutamic-type peptidase activity | molecular function | ASTL |
| glutaminase activity | molecular function | NADSYN1, GLS2, GLS |
| glutamine N-acyltransferase activity | molecular function | GLYATL1 |
| glutamine-fructose-6-phosphate transaminase (isomerizing) activity | molecular function | GFPT1 |
| glutamine-phenylpyruvate transaminase activity | molecular function | KYAT1 |
| glutamine-tRNA ligase activity | molecular function | LARS1, QARS1 |
| glutaminyl-peptide cyclotransferase activity | molecular function | QPCTL, QPCT |
| glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity | molecular function | QRSL1, GATB, GATC |
| glutaryl-CoA dehydrogenase activity | molecular function | GCDH |
| glutaryl-CoA hydrolase activity | molecular function | ACOT4 |
| glutathione binding | molecular function | GSTM1, GSTP1, MGST1, LANCL1, MGST2, PTGES2, PTGES, GSTM4, MMACHC |
| glutathione dehydrogenase (ascorbate) activity | molecular function | GSTO1, GSTO2 |
| glutathione disulfide oxidoreductase activity | molecular function | GLRX2, GLRX |
| glutathione hydrolase activity | molecular function | GGTLC1, GGTLC2, GGT7, GGT1 |
| glutathione oxidoreductase activity | molecular function | GLRX |
| glutathione peroxidase activity | molecular function | GPX1, MGST1, GSTT1, GPX4, GSTK1, ALOX5AP, MGST3, MGST2, GSTA1, PRDX6, GPX3, GSTZ1, GPX2, LTC4S, GPX7 |
| glutathione specific gamma-glutamylcyclotransferase activity | molecular function | CHAC1 |
| glutathione transferase activity | molecular function | GSTM1, GSTP1, MGST1, GSTT1, GSTK1, GDAP1L1, ALOX5AP, LANCL1, MGST3, MGST2, GSTA1, GSTO1, GSTO2, GSTZ1, GSTM4, GSTA3, LTC4S, HPGDS, GSTA4, GSTA2, GSTM5 |
| glutathione-disulfide reductase activity | molecular function | GSR |
| glyceraldehyde oxidoreductase activity | molecular function | AKR1B1 |
| glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity | molecular function | ALDH9A1, ALDH3A2, ALDH2 |
| glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | molecular function | GAPDH, GAPDHS |
| glycerate dehydrogenase activity | molecular function | GRHPR |
| glycerate kinase activity | molecular function | GLYCTK |
| glycerol channel activity | molecular function | AQP5, AQP7, AQP11, AQP9, AQP3, AQP10 |
| glycerol kinase activity | molecular function | GK2, GK, GK5 |
| glycerol transmembrane transporter activity | molecular function | AQP2, AQP1 |
| glycerol-1-phosphatase activity | molecular function | PGP |
| glycerol-3-phosphatase activity | molecular function | PGP |
| glycerol-3-phosphate dehydrogenase (quinone) activity | molecular function | GPD2 |
| glycerol-3-phosphate O-acyltransferase activity | molecular function | GPAM, GPAT3 |
| glycerone kinase activity | molecular function | TKFC |
| glycerone-phosphate O-acyltransferase activity | molecular function | GNPAT |
| glycerophosphocholine cholinephosphodiesterase activity | molecular function | ENPP6 |
| glycerophosphocholine phosphodiesterase activity | molecular function | GDPD5, GPCPD1 |
| glycerophosphodiester phosphodiesterase activity | molecular function | GDE1, ENPP6 |
| glycerophosphoinositol glycerophosphodiesterase activity | molecular function | GDE1 |
| glycerophosphoinositol inositolphosphodiesterase activity | molecular function | GDPD2 |
| glyceryl-ether monooxygenase activity | molecular function | AGMO |
| glycine amidinotransferase activity | molecular function | GATM |
| glycine binding | molecular function | GLDC, GRIN1, GNMT, GLRA3, GRIN2B, GLRA1, GRIN3A, GRIN3B, SRR, CEP104, GLRA2 |
| glycine C-acetyltransferase activity | molecular function | GCAT |
| glycine dehydrogenase (decarboxylating) activity | molecular function | GLDC |
| glycine hydroxymethyltransferase activity | molecular function | SHMT1, SHMT2 |
| glycine N-acyltransferase activity | molecular function | GLYATL1, GLYAT |
| glycine N-benzoyltransferase activity | molecular function | GLYAT |
| glycine N-choloyltransferase activity | molecular function | BAAT |
| glycine N-methyltransferase activity | molecular function | GNMT |
| glycine transmembrane transporter activity | molecular function | SLC25A38, SLC36A1, SLC36A2, SLC36A3, SLC6A9, SLC6A5, SLC38A5, SLC32A1 |
| glycine-gated chloride ion channel activity | molecular function | GLRA3, GLRA2 |
| glycine-tRNA ligase activity | molecular function | GARS1 |
| glycine:sodium symporter activity | molecular function | SLC6A20, SLC6A9, SLC6A5 |
| glycogen (starch) synthase activity | molecular function | GYS2, GYS1 |
| glycogen binding | molecular function | PPP1R3D, PPP1R3C, PPP1R3B, STBD1 |
| glycogen debranching enzyme activity | molecular function | AGL |
| glycogen phosphorylase activity | molecular function | PYGL, PYGB, PYGM |
| glycogen synthase activity, transferring glucose-1-phosphate | molecular function | GYS2, GYS1 |
| glycogenin glucosyltransferase activity | molecular function | GYG1, GYG2 |
| glycolate oxidase activity | molecular function | HAO1 |
| glycolipid binding | molecular function | HSPA2, CD1C, GLTP, CLN3, PLEKHA8 |
| glycolipid mannosyltransferase activity | molecular function | PIGM, PIGV, PIGB |
| glycolipid transfer activity | molecular function | GLTP, PLEKHA8 |
| glycoprotein 6-alpha-L-fucosyltransferase activity | molecular function | FUT8 |
| glycoprotein binding | molecular function | TGFB1, VWF, SERPINA1, ITGB1, VIM, FGFR1, B2M, HSPA5, IGF2R, PLAT, CDH1, SHH, PIP, AZGP1, ACE2 |
| glycoprotein endo-alpha-1,2-mannosidase activity | molecular function | MANEA |
| glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity | molecular function | ABO |
| glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | molecular function | C1GALT1C1, C1GALT1 |
| glycosaminoglycan binding | molecular function | DCN, TGFBR3, SERPINA5, SHH, PRNP, PTN, EXTL2, SPOCK2, SGSH, BGN, ABI3BP, GNS, CRISPLD2, TGFBR2, EGFLAM, SMOC2, SULF1, ENG, PODXL2, VIT, LTBP4, HABP2, SULF2, NDNF |
| glycosphingolipid binding | molecular function | IL2, SELP, LYN, SELL |
| glycosylated region protein binding | molecular function | CD200R1 |
| glycosylceramidase activity | molecular function | LCT |
| glycosylphosphatidylinositol phospholipase D activity | molecular function | GPLD1 |
| glycylpeptide N-tetradecanoyltransferase activity | molecular function | NMT1, NMT2 |
| glyoxalase (glycolic acid-forming) activity | molecular function | PARK7 |
| glyoxalase III activity | molecular function | PARK7 |
| glyoxylate reductase (NADP) activity | molecular function | GRHPR |
| GMP binding | molecular function | KRAS, RAB26, MPPED2 |
| GMP reductase activity | molecular function | GMPR2, GMPR |
| GMP synthase (glutamine-hydrolyzing) activity | molecular function | GMPS |
| GMP synthase activity | molecular function | GMPS |
| gonadotropin hormone-releasing hormone activity | molecular function | GNRH1 |
| gonadotropin-releasing hormone receptor activity | molecular function | GNRHR, GPR173 |
| GPI-anchor transamidase activity | molecular function | PIGS, GPAA1, PIGK, PIGT, PIGU |
| GPI-linked ephrin receptor activity | molecular function | NTRK1, EPHA4, EPHA7, EPHA3, EPHA8 |
| Gq/11-coupled serotonin receptor activity | molecular function | HTR2C |
| granulocyte colony-stimulating factor binding | molecular function | CSF3R |
| granulocyte colony-stimulating factor receptor binding | molecular function | CSF3 |
| group II metabotropic glutamate receptor activity | molecular function | GRM3, GRM2 |
| group III metabotropic glutamate receptor activity | molecular function | GRM4, GRM8, GRM6, GRM7 |
| growth factor activity | molecular function | TIMP1, EGF, TGFB1, AMH, IL4, IL6, INHBA, TGFB3, LIF, VEGFA, IL11, KITLG, IL10, BDNF, IL12A, IGF2, NODAL, BMP7, LEP, PGF, GDF15, GDF9, BMP15, GH1, IGF1, IL5, BMP4, HGF, IL2, NRG1, CD320, FGF17, NGF, FGF8, INHA, FGF3, FGF9, CSF1, GDNF, PROK1, CECR1, AREG, CCN2, FGF12, RABEP1, OSGIN2, CCN6, IL7, TDGF1, NRG3, PDGFB, TGFA, PTN, PDGFD, MANF, NRG4, NTF4, IL34, MIA, FGF23, GDF11, MDK, DKK1, IL3, HDGF, CSHL1, ANGPTL3, GH2, FGF5, BMP1, AMBN, EREG, PDGFA, BMP5, TGFB2, FGF20, NENF, NRG2, OSGIN1, LEFTY1, GPI, CDNF, VEGFC, CXCL1, HBEGF, HDGFL3, OSM, BMP6, FGF18, CSF3, GRN, CCN3, GMFB, NRTN, FGF22, TYMP, FGF7, BTC, MSTN, PSPN, FGF19, PPBP, TFF1, FGF6, BMP2, VEGFB, GDF3, PDGFC, FGF21, VGF, FGF2, CSH1, NTF3, THBS4, INHBC, INHBE, GDF7, JAG2, GMFG, CSPG5, F2, JAG1, GDF2, LEFTY2, GDF1, CXCL12, AGT, FGF1, FGF14, CLCF1, CSH2, OGN, CNTF, THPO, GFER, FGF10, GDF5, EFEMP1, MACC1 |
| growth factor binding | molecular function | IL6ST, ERBB2, FLT1, KDR, A2M, BMPR2, CCN1, LTBP2, LTBP1, FGFBP3, ACVR1B, IGFBP1, ACVR1, FLT4, RHBDF1, ACVR2B, TEK, GHRHR, IGFBP7, LIFR, ACVR1C, NRP2, LRRC32, GHR, IGFBP4, TGFBR1, ACVR2A, DUSP1, IGFBP2, ERBB3, PDGFRB, LTBP3, FGFBP1, NRROS, OSMR, FGFBP2, PDGFRA, NRP1, IGFBP5, HTRA1, NKD2, CSF1R, RHBDF2, LTBP4, IGFBP6 |
| growth factor receptor binding | molecular function | APP, SRC, PDGFB, SLC9A3R1, PDGFD, PSEN1, PDGFA, PDGFC |
| growth hormone receptor activity | molecular function | GHR |
| growth hormone receptor binding | molecular function | TYK2, GH1, JAK2, SOCS2, CSHL1, GH2, JAK1, CSH1, CSH2 |
| growth hormone secretagogue receptor activity | molecular function | GHSR |
| growth hormone-releasing hormone activity | molecular function | GHRL |
| growth hormone-releasing hormone receptor activity | molecular function | GHSR, GHRHR, TAPT1 |
| GTP binding | molecular function | GNAS, FKBP4, HSP90AA1, GNAO1, GNAI1, TUBB2B, INSR, CDC42, RAP1A, TUBB3, 39326, 41153, DNM1L, TUBA4A, TUBA3C, THG1L, TUBA8, RABL2A, 38231, ANXA6, SPAG1, DIRAS3, GLUD1, H1-4, ARF4, RAB9A, DAP3, EEF1A1, SEPTIN2, GFM1, GTPBP4, IFT22, RAB18, SEPTIN9, RAB21, RNGTT, GSPT1, RAB11A, RAB2B, RAB40A, RIT1, SAR1A, ARL8B, GNL3L, SEPTIN10, DRG1, RAB29, SEPHS1, RAB38, RAP2B, IFI44L, GNAI2, RAB27A, RAB1A, RHOU, NIN, RAB6B, DNAJC27, SRPRA, RALA, ADSS2, EIF2S3, GLUD2, RND2, RAB2A, RASL11B, GNL3, RTCB, ERAL1, KRAS, RAB4A, ARL2, RABL3, NUGGC, GSPT2, IRGQ, RASD2, RAB3C, CPLANE2, GNAI3, RRAS, RAB6A, GNL1, RAB25, ARL9, RRAGA, GTPBP8, ATL1, GBP5, ARHGAP35, GNAZ, RAB5A, AK4, ARL3, ARL16, ARHGEF5, RAB31, RAB32, GNL2, TUBB2A, PCK2, REM2, RAB8B, ARL11, LANCL2, OLA1, RAB20, GTPBP1, RHOD, EEF2, GNAT2, GEM, RND3, ARF1, ARF5, RHOG, RAB40B, RAB35, RRAGB, EFL1, SRL, ARL6, RAB22A, DNM3, RAB27B, OPA1, SCG5, NUDT2, EIF5, RCC1L, SUCLG2, RIT2, TUBE1, SAR1B, MX1, GUCY2F, RAB15, RRAS2, RAB30, ARL13B, GIMAP6, ARL14, EHD4, NKIRAS1, RAB3B, GBP2, RAB14, |
| GTP cyclohydrolase I activity | molecular function | GCH1 |
| GTP diphosphatase activity | molecular function | NUDT1 |
| GTP phosphohydrolase activity | molecular function | ENTPD8, ENTPD3 |
| GTP-dependent protein binding | molecular function | CDC42, RAB38, AP3B1, AP1G1, RAB3C, RAPGEF6, RAB32, RASGRP4, RAB3B, UNC13B, EEA1, PARD6A, GCH1, RAB5B, RAB34, RAB3D, MRAS |
| GTP-dependent protein kinase activity | molecular function | LRRK2 |
| GTP-Rho binding | molecular function | CDC42EP5, TNFAIP1, KCTD13, ROCK2, STXBP6, ANLN, ROCK1, CDC42EP2, PKN2, PKN3, CDC42EP3, CDC42EP4, CDC42EP1, EXOC1, TRIOBP, KCTD10, RTKN, PKN1 |
| GTPase activating protein binding | molecular function | AKT1, GNAO1, GNAI1, CDH1, PIN1, GNAI3, TSC1, ARL3, PLCD1, TUBB, GAPVD1, RGS14, PLXNB1, FMNL1, FMNL3 |
| GTPase activator activity | molecular function | A2M, ARHGDIA, SOS1, RANGAP1, AGFG1, ASAP2, SIPA1L3, RASA1, ACAP2, TBC1D15, RIN2, ELMOD3, EVI5, RABEP1, SEC23B, MTSS2, RGPD4, USP6NL, ARFGEF1, CHN1, IQGAP1, SYDE2, RALGAPA1, ARAP1, ALS2, ARHGAP32, GDI2, ACAP1, RASGRP3, RGS17, ERRFI1, RAPGEF2, ARHGEF11, SRGAP3, RALBP1, DEPDC1, DAB2IP, TBC1D19, TBCK, NPRL2, ANKRD27, AGAP4, VAV3, GNB5, RGS16, CHML, OCRL, RASA2, PREX2, TBC1D1, DLC1, ARHGAP9, SIPA1L2, RABGAP1, RGS20, BCR, ABR, BNIP2, ARHGEF6, GARNL3, ARHGAP35, ARHGAP33, RINL, RALGAPB, ARHGAP45, ADAP2, RASAL2, DEPDC5, STXBP5, ARHGAP22, ARHGAP24, ARAP2, TBC1D20, RIC8B, TBC1D30, TBC1D10C, ARFGAP1, TBC1D22B, GIT1, RGS11, ADPRH, RIN1, ARHGAP17, ARAP3, TBC1D13, ARHGEF12, LARS1, CDC42EP2, ARHGAP8, ARHGAP5, ARHGAP27, AGAP3, STARD13, TBC1D3D, TBC1D3I, TBC1D3E, TBC1D3F, MYO9A, TBC1D3L, SRGAP2, RAP1GDS1, LLGL1, RALGAPA2, TBC1D26, DOCK5, HACD3, ADGRB3, RGS2, CHN2, ARHGAP19, ARHGAP31, RGS10, TBC1D4, TBC1D8, ARHGAP1, SEC23A, ARHGAP21, ARHGAP18, TBC1D22A, RANBP3, ECT2, ARHGEF10L, RGS5, TBC1D12, GNAQ, TBC1D28, TBC1D10B, ARHGAP29, |
| GTPase activity | molecular function | GNAS, GNAO1, GNAI1, TUBB2B, CDC42, RAP1A, TUBB3, DNM1L, TUBA4A, TUBA3C, TUBA8, RABL2A, 38231, DIRAS3, ARF4, RASA1, RAB9A, EEF1A1, SEPTIN2, GFM1, GTPBP4, IFT22, RAB18, SEPTIN9, RAB21, DDX3X, GSPT1, RAB11A, RAB2B, RAB40A, RIT1, SAR1A, ARL8B, SEPTIN10, DRG1, RAB29, RAB38, RAP2B, GNAI2, GNB3, RAB27A, RAB1A, RHOU, RAB6B, DNAJC27, RGS17, SRPRA, RALA, EIF2S3, RND2, RAB2A, RASL11B, GNB5, RGS16, GNG7, KRAS, RAB4A, ARL2, RABL3, NUGGC, GSPT2, RASD2, RAB3C, CPLANE2, RGS20, GNAI3, RRAS, RAB6A, GNL1, RAB25, GNB1, RRAGA, ATL1, GBP5, ARHGAP35, GNAZ, RAB5A, ARL3, RAB31, RAB32, GNL2, TUBB2A, REM2, RAB8B, RAB20, GTPBP1, RHOD, EEF2, GNAT2, GEM, RND3, ARF1, ARF5, RHOG, RAB40B, RAB35, TBCC, RRAGB, EFL1, ARL6, RAB22A, DNM3, RAB27B, OPA1, RIT2, TUBE1, SAR1B, RGS11, MX1, NUDT1, RAB15, RRAS2, RAB30, NKIRAS1, RAB3B, GBP2, RAB14, ARF3, ARHGAP5, MFN1, GUF1, GTPBP3, AGAP3, RHOF, RAB23, TUBB, TUBA3D, GNAL, RAB7A, GNGT1, RAB39A, NKIRAS2, EIF5B, RALB, RHOQ, RGS2, GNG10, RAN, TUBB4B, GNA12, EEF1A2, RHEB, RAB11B, ADSS1, GFM2, RGS10, RHOBTB3, M |
| GTPase binding | molecular function | HSP90AA1, ENO1, RASA1, EPRS1, GNB3, IARS1, FNBP1L, GNB1, YBX1, SPTBN1, RRAGB, STOML2, MARCHF5, ULK1, GOLGA4, BNIP3, CLTA, BECN1, AIMP1, RRAGD, POU4F1, LAMTOR1, PPP1R9A, LCP1, PAK3, GNB2, PREB, SH3GL1, RASIP1, AMBRA1, ATG16L1 |
| GTPase inhibitor activity | molecular function | IQGAP1, IQGAP2, PDE6D, ARL2, IPO5, DGKI, GPS2, CPEB2, RTKN, GPS1, CDC42SE1, RHOH, SLIT2 |
| GTPase regulator activity | molecular function | WASL, RIN2, GPSM2, PCP2, RIMS1, ARL2BP, GPSM1, KRIT1, IPO7, ARHGDIG, RAP1GAP, WAS, RGS14, RALGDS, RGS12, RUNDC3A |
| guanidinoacetate N-methyltransferase activity | molecular function | GAMT |
| guanine deaminase activity | molecular function | GDA |
| guanine phosphoribosyltransferase activity | molecular function | HPRT1 |
| guanine/thymine mispair binding | molecular function | MLH1, MSH2, MSH6 |
| guanosine phosphorylase activity | molecular function | LACC1 |
| guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity | molecular function | HDDC3 |
| guanosine-diphosphatase activity | molecular function | ENTPD5, CANT1 |
| guanyl nucleotide binding | molecular function | GNAS, GNAO1, GNAI1, GNAI2, GNAI3, GNAZ, RAB5A, GNAT2, GNAL, GNA12, GNA11, GNAQ, GNA14, GNA15 |
| guanyl ribonucleotide binding | molecular function | RRAGB |
| guanyl-nucleotide exchange factor activity | molecular function | SOS1, SBF1, LAMTOR3, DENND2A, RALGPS1, RGL4, ARHGEF3, ARFGEF1, ARHGEF10, KALRN, NUCB2, ALS2, RAB3IP, CYTH3, ARHGEF7, RALGPS2, RASGRP3, PCP2, C9orf72, FBXO8, RAPGEF2, ARHGEF11, LAMTOR5, CCZ1, DENND4A, DENND1C, RPGR, ANKRD27, EIF2B3, PSD3, RAPGEFL1, VAV3, EIF2B1, PREX2, DENND6A, ARFGEF2, MCF2, BCR, ABR, ARHGEF6, DENND1A, RAPGEF6, DENND2D, RANGRF, ARHGEF9, RASGRP1, ARHGEF5, CCDC88A, RINL, ARHGEF4, RASGRP4, RIC8B, RCC2, DENND5A, RASGRP2, RCC1L, HPS4, IQSEC1, P2RY12, ARHGEF12, SERGEF, EEF1D, GCGR, RAPGEF1, DOCK11, DOCK9, RGL1, PLCE1, SOS2, DENND1B, SBF2, ARHGEF40, DOCK5, PLEKHG3, TIAM1, RGL3, FGD6, ARHGEF28, ARHGEF39, DOCK7, FARP1, DENND11, DENND6B, DOCK8, SPATA13, PLEKHG2, ECT2, ARHGEF10L, DIS3, SH3BP5, VAV2, OBSCN, DENND4C, MCF2L2, DOCK3, ARHGEF2, CCDC88C, MYCBP2, AKAP13, DOCK1, PLEKHG4, FNIP1, ARHGEF37, TRIO, RABIF, EIF2B2, GAPVD1, RIC1, FLCN, SMCR8, RGP1, DOCK6, ITSN2, RGL2, RCC1, LAMTOR1, TAGAP, ARHGEF1, FGD4, PSD, RASGRF2, MCF2L, EEF1B2, EIF2B5, KNDC1, MON1A, NGEF, RAB3IL1, DENND10, ARHGEF17, CYTH2, FARP2, F |
| guanylate cyclase activator activity | molecular function | GUCA2B, GUCA2A |
| guanylate cyclase activity | molecular function | GUCY2F, GUCY1B1, GUCY1A2, GUCY1A1, NPR1, GUCY2D, NPR2 |
| guanylate cyclase inhibitor activity | molecular function | PDZD3 |
| guanylate cyclase regulator activity | molecular function | GUCA1A |
| guanylate kinase activity | molecular function | GUK1, DLG1, CASK, MPP1, LRGUK, MAGI3, CARD11, DLG2 |
| guanylyltransferase activity | molecular function | TENT4B, TENT4A |
| H2A histone acetyltransferase activity | molecular function | NAA40 |
| H3 histone acetyltransferase activity | molecular function | BRCA2, MCM3AP, KAT2A |
| H3K9me3 modified histone binding | molecular function | DPF2 |
| H4 histone acetyltransferase activity | molecular function | BRCA2, USP22, NAA40, NAA50, KAT5, HAT1, NAA60 |
| H4K20me3 modified histone binding | molecular function | PWP1, TTLL12 |
| heat shock protein binding | molecular function | FKBP4, BAX, BAK1, HSPA9, HSPA1A, HSPA1B, HSPA1L, PACRG, DMPK, HSPA8, FKBP5, DNAJA4, HSPA14, DNAJA2, ST13, METTL21C, HDAC2, IRAK1, BCOR, DNAJC7, METTL21A, PRKN, METTL18, LMAN2, STUB1, TOMM34, ITGAM, PPID, EEF1D, CDC37L1, APOA1, HSPA13, EEF1AKMT3, METTL22, TPR, ZFP36, METTL23, FAF1, PPP5C, ETFBKMT, DNAJC9, ITGB2, HTT, SPN, HSPA6, CAMKMT, TFAM, LIMK1, PDXP, CDC37 |
| HECT domain binding | molecular function | BPY2 |
| hedgehog family protein binding | molecular function | PTCH2, HHIP, PTCH1 |
| hedgehog receptor activity | molecular function | B9D1, PTCH2, PTCH1 |
| helicase activity | molecular function | DDX3Y, ERCC2, CHD2, DDX4, CHD7, DDX25, DICER1, TDRD9, MOV10L1, MCM3, HELQ, DDX1, MCM8, DDX3X, SMARCA2, G3BP1, SRCAP, DHX40, IFIH1, DDX47, DDX43, DDX19B, XRCC5, EIF4A2, DDX46, SUPV3L1, DHX36, SMARCA5, MTREX, SMARCA4, DDX39B, DHX32, DDX55, TTF2, ATRX, DDX23, RECQL5, ERCC6, DDX10, SETX, CHD1L, DDX31, DDX21, MCM9, RUVBL2, DDX52, EIF4A1, HELZ2, DDX24, HLTF, ASCC3, UPF1, DHX58, RECQL, DDX50, DHX15, XRCC6, DHX29, SLFN11, NAV2, RTEL1, DDX41, CHD5, SMARCAL1, DDX20, DDX39A, AQR, DDX6, HELZ, CHD9, TDRD12, DDX49, BTAF1, SMARCA1, MCM5, CHD4, ZRANB3, DDX60L, RUVBL1, DDX53, FBH1, DDX18, GTF2F2, DHX57, DHX30, DDX17, SNRNP200, BLM, CHD6, MOV10, MCM4, MCM7, DDX42, DDX60, SMARCAD1, MCM6, BRIP1, DHX16, RECQL4, DHX37, SKIV2L, DDX11, DDX56, CHD3, HELB, CHD8, HELLS, DDX51, EP400, DHX33, EIF4A3, DHX34, DDX54, IGHMBP2, MCM2, DHX35, RAD54L2, RAD54B, RAD54L, DDX27, DDX19A |
| heme binding | molecular function | CYP1A1, CYP19A1, PTGS1, NOS3, PTGS2, CYP24A1, CYP17A1, CYP1A2, HMOX1, CYP2B6, CYP11A1, CYP11B1, CBS, CAT, SRC, LPO, NOS2, CYCS, CYP21A2, CYP11B2, CYP1B1, CYP26B1, CYB5A, MT-CO1, NOX5, FLVCR2, PGRMC2, JAK2, CYP2J2, IDO2, CYB561D1, CYB5B, CYP4A11, CYP4F3, HEBP1, CYP20A1, FLVCR1, CYBB, CYP2R1, CYB5D2, EIF2AK1, TPO, IDO1, HBG2, PGRMC1, BACH1, CYP2A7, SLC48A1, PXDNL, CYP2C8, SUOX, STEAP4, SDHD, EPX, CYBA, CYP4F8, HEBP2, CYP26A1, CYP4B1, PTGES2, HBD, CYP2A6, CYP2C19, HBB, GUCY1B1, CYP4F22, CYP8B1, GUCY1A2, GUCY1A1, STC2, HBZ, HMOX2, CYP27B1, PTGIS, CYB5R4, FA2H, LOXHD1, CYP3A5, CYP2C18, ADGB, MB, NR1D1, CYP4F12, ABCB6, DUOX2, CYC1, CYP51A1, SDHC, MPO, HBQ1, PXDN, HRG, CYP2E1, TBXAS1, CYP4F2, CYP4Z1, CYP4X1, NGB, HBA1, CYP26C1, CYP46A1, AMBP, CYP2D6, CYP2S1, DUOX1, CYP2D7, CYP2W1, CYGB, THAP4, CYP4F11, CYP2C9, CYP3A43 |
| heme oxygenase (decyclizing) activity | molecular function | HMOX1, HMOX2 |
| heme transmembrane transporter activity | molecular function | FLVCR2, PGRMC2, FLVCR1, SLC48A1, ABCB7 |
| heme-copper terminal oxidase activity | molecular function | MT-CO3 |
| hemi-methylated DNA-binding | molecular function | EGR1, UHRF1 |
| hemoglobin alpha binding | molecular function | HBG2, HBD, HBB |
| hemoglobin binding | molecular function | AHSP, HBB, HPR, HP, SLC4A1 |
| heparan sulfate 2-O-sulfotransferase activity | molecular function | HS2ST1 |
| heparan sulfate 6-O-sulfotransferase activity | molecular function | HS6ST3, HS6ST1, HS6ST2 |
| heparan sulfate binding | molecular function | COL11A1, PTN, MDK, DMBT1 |
| heparan sulfate N-acetylglucosaminyltransferase activity | molecular function | EXT1, EXT2 |
| heparan sulfate N-deacetylase activity | molecular function | NDST1, NDST3 |
| heparan sulfate proteoglycan binding | molecular function | FST, LPL, CFH, HPSE2, PTPRC, ITGA2, FGF20, LRP1, AZU1, PTPRS, HRG, COMP, AGRN, PLA2G2D, SEMA5A |
| heparan-alpha-glucosaminide N-acetyltransferase activity | molecular function | HGSNAT |
| heparanase activity | molecular function | HPSE, HPSE2 |
| heparin binding | molecular function | SERPINC1, APOE, VEGFA, ANOS1, APOB, FGFR2, APP, FGFR1, BMP7, PGF, TGFBR3, ADAMTS1, ADAMTS5, LTF, SERPINA5, BMP4, CCL5, FN1, MMP7, BSPH1, ELANE, FGF9, SAA1, CECR1, CCN1, COL11A1, CCN2, FGF12, LTBP2, LRTM1, RPL29, TNXB, CCL8, FGFBP3, CCN6, LPL, NELL1, RTN4R, CXCL11, PDCD5, MPIG6B, PTPRF, PTN, FBN1, LIPG, ZNF207, GPNMB, CFH, CXCL6, SLIT1, EVA1C, APLP2, FSTL1, THBS1, MDK, LAMC2, PF4, CTSG, LIPC, HDGF, PRELP, POSTN, NAV2, IMPG2, ANGPTL3, PTPRC, SELP, RSPO2, GREM2, PCSK6, RPL22, ABI3BP, NRP2, ECM2, LIPH, AOC1, LRPAP1, ZNF146, HBEGF, CLEC3B, CCL23, APOA5, NELL2, RSPO3, VTN, PRG2, CCN3, CRISPLD2, CHRD, MPO, COL5A1, FGF7, PLA2G5, HSD17B12, SMOC2, PCOLCE2, MSTN, SOD3, AZU1, COL5A3, VEGFB, CCL7, H1-1, PTPRS, FGFBP1, PRSS57, HRG, FGF2, SELL, THBS4, ADAMTS15, LXN, SERPINA10, NRP1, ANG, PF4V1, FGFR4, COMP, COL16A1, COL19A1, FBLN7, LGR6, ADAMTS8, F2, PTCH1, PCOLCE, TMEM184A, THBS2, THBS3, COL13A1, PLA2G2D, ADAMTS3, SLIT3, SLIT2, CCN4, FGF1, RTN4RL1, FGF14, COL25A1, CCN5, LRTM2, NDNF, FGF10, APOH, CXCL10, APLP1, CCL15 |
| heparosan-N-sulfate-glucuronate 5-epimerase activity | molecular function | GLCE |
| hepatocyte growth factor binding | molecular function | SRPX2 |
| hepatocyte growth factor receptor binding | molecular function | ESM1 |
| hepoxilin A3 synthase activity | molecular function | ALOXE3 |
| heptaldehyde:oxygen oxidoreductase activity | molecular function | AOX1 |
| heteroduplex DNA loop binding | molecular function | XPC, MSH2 |
| heterotrimeric G-protein binding | molecular function | CETN2, CETN1, ADRA2A |
| hexaprenyldihydroxybenzoate methyltransferase activity | molecular function | COQ3 |
| hexokinase activity | molecular function | HKDC1, HK2, GCK, HK3 |
| hexosaminidase activity | molecular function | HEXD |
| high voltage-gated calcium channel activity | molecular function | CACNA1S, CACNA1C, CACNA1A, CACNB4, CACNA1D, CACNB1, CACNB3, CACNA1B, CACNB2 |
| high-affinity arginine transmembrane transporter activity | molecular function | SLC25A29 |
| high-affinity glutamate transmembrane transporter activity | molecular function | SLC1A2, SLC1A3, SLC1A6 |
| high-affinity inorganic phosphate:sodium symporter activity | molecular function | SLC20A1 |
| high-affinity lysine transmembrane transporter activity | molecular function | SLC25A29 |
| high-affinity sodium:dicarboxylate symporter activity | molecular function | SLC13A3 |
| high-density lipoprotein particle binding | molecular function | SCARB1, APOL2, APOA1, TREM2, APOL5, CD36 |
| high-density lipoprotein particle receptor activity | molecular function | ILDR1, SCARB1 |
| high-density lipoprotein particle receptor binding | molecular function | APOA1, APOC3 |
| histamine N-methyltransferase activity | molecular function | HNMT |
| histamine oxidase activity | molecular function | AOC1 |
| histamine receptor activity | molecular function | HRH1, ZNF219, HRH4, HRH3, HRH2, HTR6 |
| histidine ammonia-lyase activity | molecular function | HAL |
| histidine-tRNA ligase activity | molecular function | HARS1, HARS2 |
| histone acetyltransferase activity | molecular function | BRCA2, KAT7, NCOA2, CLOCK, TADA1, CDY2A, CDY1, TADA3, TAF12, EPC2, SRCAP, DPF1, RSF1, SUPT3H, BAZ1A, NCOA3, GTF2B, CREBBP, MCM3AP, SUPT7L, ING3, TAF5L, TAF1, EP300, PHF10, KAT5, NCOA1, EPC1, TADA2A, ATF2, TAF10, HAT1, KAT2A, KAT6A, KAT2B, KAT14, DPF2, KAT6B, NAA60, TAF9, GTF3C4 |
| histone acetyltransferase activity (H4-K12 specific) | molecular function | KAT2A |
| histone acetyltransferase binding | molecular function | TP53, HIF1A, SP1, PCNA, MEF2A, TAF7L, GLI3, EID1, KANSL1L, EGR1, TRIM68, ECD, TAF7, SIRT2, ETS1, KANSL1, TRIP4, MYOCD, EPAS1, CITED2, BCAS3, NR4A3, ZBTB7A, MTF1 |
| histone acetyltransferase regulator activity | molecular function | PYGO2, EID1 |
| histone binding | molecular function | RAG1, BRDT, CTCFL, CHD2, H2AFX, RNF8, PRMT6, PYGO2, HIST1H4A, NASP, RNF20, ATAD2, KDM5B, JAK2, NPM1, SMARCA2, SAMD13, SRCAP, DPF1, UIMC1, SUPT16H, AIRE, NAP1L1, PHC1, MBTD1, RNF168, USP16, USP3, SMARCA5, ANP32A, SMARCA4, DTX3L, ANP32B, RSF1, COPRS, CTSL, DEK, SNCA, ATRX, IPO9, NAP1L4, TSPYL2, RESF1, BAZ1B, TNKS, NCAPD3, CKS1B, PHF6, SAMD11, WDR5, SART3, TSPYL5, HIRA, GLYR1, USP51, L3MBTL4, SAP30L, SBNO2, L3MBTL1, SBNO1, WRAP53, SCML1, KMT2D, SPTY2D1, HJURP, MCM3AP, SAMD7, SFMBT1, PHC2, SMARCC2, NAP1L3, PRKCB, TSPY3, TSPY10, MLLT3, TSPY1, PWWP2A, UHRF2, RBBP4, WDTC1, KMT2C, PHF10, KAT5, DNAJC2, BAZ2A, SCML2, MLLT10, MYSM1, ANP32E, IPO7, FH, TSPYL6, UHRF1, BRD1, TP53BP1, PHC3, SMARCC1, BCAS3, LEF1, HAT1, TBL1X, RCC1, MLLT6, GRWD1, HPF1, NAP1L2, NPM3, SSRP1, USP49, KMT5C, STPG4, PTMA, L3MBTL2, NAP1L5, VPS72, PKN1, KDM5A, SET, KAT6A, SCMH1, HINFP, CKS2, NCAPD2, CHD8, TSPYL4, INO80, NOC2L, APBB1, TONSL, SFMBT2, DPF2, L3MBTL3, YEATS2, MCM2, SCML4, KDM1B, KAT6B, PRMT7, ATAD2B, TSPY4, ASF1B |
| histone butyryltransferase activity | molecular function | EP300 |
| histone crotonyltransferase activity | molecular function | EP300 |
| histone deacetylase activity | molecular function | MTA2, SIN3A, HDAC4, MIER3, MIER1, HDAC11, HDAC2, SIN3B, SUDS3, HDAC9, HDAC8, SIRT2, MIER2, ATXN3, HDAC7, HDAC3, SIRT6, SIRT7, HDAC6, HDAC10, HDAC5, BRMS1 |
| histone deacetylase activity (H4-K16 specific) | molecular function | HDAC9 |
| histone deacetylase binding | molecular function | NRIP1, HIF1A, HSP90AA1, SP1, DNMT1, DNMT3B, MTA2, PARP1, MAPK8, HSPA1A, HSPA1B, MEF2A, CDC20, TOP2A, USF1, ZMYND15, GLI3, HDAC4, KLF4, NUDT21, KPNA2, CIR1, MTA3, MIER3, MIER1, DHX36, BEX4, SFPQ, HNRNPD, HDAC2, MAGEA2, UHRF1BP1, BCOR, NKX3-1, SUDS3, AKAP8, HES1, PHF6, HDAC9, PRKN, CCND1, NACC2, PRDM1, RELA, MEF2C, SIRT2, MIER2, PKN2, DDX20, RAD9A, YWHAE, RBBP4, NIPBL, WDTC1, SIX3, RAC1, INSM1, CHD4, NCOR2, NR2C1, SP2, MEF2D, TRAF6, ZNHIT1, TOP2B, CRY1, YWHAB, MYOCD, HEY2, LEF1, HDAC3, NCOR1, ANKRA2, DACT1, HDAC6, H1-5, SRF, HIC1, NACC1, PKN1, KAT2A, HDAC10, RFXANK, CBX5, KAT2B, SMG5, HDAC5, BRMS1, AKAP8L, MEF2B, ZBTB7B, CAMTA2, TFAP4, ANKRD1, GCM1, TP53, RARA, HOXA10, BHLHE41 |
| histone deacetylase inhibitor activity | molecular function | SKI, UCN |
| histone deacetylase regulator activity | molecular function | MAPK8, TP53 |
| histone demethylase activity | molecular function | KDM5C, KDM5D, KDM5B, KDM4A, PHF2, KDM4C, KDM4D, JARID2, PHF8, KDM4B, KDM5A |
| histone demethylase activity (H3-dimethyl-K4 specific) | molecular function | KDM5B, KDM5A, KDM1B |
| histone demethylase activity (H3-K27 specific) | molecular function | KDM6B, UTY, PHF8 |
| histone demethylase activity (H3-K36 specific) | molecular function | RIOX2, KDM4A, RIOX1, KDM4C, PHF8, KDM2A, KDM4B, KDM8 |
| histone demethylase activity (H3-K4 specific) | molecular function | KDM5C, KDM5D, KDM5B, RIOX2, RIOX1 |
| histone demethylase activity (H3-K9 specific) | molecular function | KDM4A, PHF2, KDM4C, KDM4D, KDM3B, PHF8, KDM4B, HR |
| histone demethylase activity (H3-monomethyl-K4 specific) | molecular function | KDM1B |
| histone demethylase activity (H3-trimethyl-K4 specific) | molecular function | KDM5B, JARID2, KDM5A |
| histone demethylase activity (H4-K20 specific) | molecular function | PHF8 |
| histone glutaryltransferase activity | molecular function | KAT2A |
| histone kinase activity | molecular function | CDK1, CCNB1, BAZ1B |
| histone kinase activity (H2A-T120 specific) | molecular function | DCAF1 |
| histone kinase activity (H3-T11 specific) | molecular function | PKN1 |
| histone kinase activity (H3-T6 specific) | molecular function | PRKCB |
| histone kinase activity (H3-Y41 specific) | molecular function | JAK2 |
| histone methyltransferase activity | molecular function | EZH2, PRMT6, EED, PRDM13, CARM1, SUZ12, PRMT2, DOT1L, KMT2C, NTMT1, PRDM4, PRMT1, PRDM7, PRDM11 |
| histone methyltransferase activity (H2A-R3 specific) | molecular function | PRMT6 |
| histone methyltransferase activity (H3-K27 specific) | molecular function | EZH2, EED, SUZ12, EHMT2, EHMT1 |
| histone methyltransferase activity (H3-K36 specific) | molecular function | SETD3, NSD1, NSD3, NSD2, SETD5, ASH1L, PRDM7, SMYD2 |
| histone methyltransferase activity (H3-K4 specific) | molecular function | SETD3, WDR82, ASH2L, CXXC1, RBBP5, WDR5, KMT2D, KMT2A, KMT2C, SETD1B, ASH1L, PRDM7, SETD1A, KMT2B |
| histone methyltransferase activity (H3-K79 specific) | molecular function | DOT1L |
| histone methyltransferase activity (H3-K9 specific) | molecular function | SETDB2, EHMT2, EHMT1, SETD5, SETDB1, SUV39H2, ASH1L, MECOM, PRDM16 |
| histone methyltransferase activity (H3-R17 specific) | molecular function | CARM1 |
| histone methyltransferase activity (H3-R2 specific) | molecular function | PRMT6 |
| histone methyltransferase activity (H4-K20 specific) | molecular function | NSD1, KMT5B, NSD2, KMT5C, KMT5A |
| histone methyltransferase activity (H4-R3 specific) | molecular function | PRMT6, PRMT1, PRMT7 |
| histone methyltransferase binding | molecular function | CBX1, CBX3, NOP56, WIZ, PRDM4, PRDM12 |
| histone pre-mRNA DCP binding | molecular function | SNRPB, SLBP |
| histone pre-mRNA stem-loop binding | molecular function | ERI1, SLBP |
| histone serine kinase activity | molecular function | AURKC, PRKAA2, AURKB |
| histone succinyltransferase activity | molecular function | KAT2A |
| histone-arginine N-methyltransferase activity | molecular function | PRMT6, CARM1, PRMT2, PRMT8, PRMT7 |
| histone-glutamine methyltransferase activity | molecular function | FBL |
| histone-lysine N-methyltransferase activity | molecular function | EZH2, PRDM9, NSD1, NSD3, SETDB2, KMT5B, EHMT2, MEN1, EHMT1, DOT1L, NSD2, SETD1B, SETD7, SETDB1, KMT2E, SUV39H2, ASH1L, TTLL12, SMYD1, SETD1A, SMYD2, KMT5A |
| HLA-A specific activating MHC class I receptor activity | molecular function | CTSH |
| HLH domain binding | molecular function | HES1, UBE2I, PKD2 |
| HMG box domain binding | molecular function | SP1, HOXA3, GATA3, MEF2C, PRRX1, EGR2, POU3F3, ALX4, DLX5, HOXC4 |
| HNK-1 sulfotransferase activity | molecular function | CHST10 |
| holocytochrome-c synthase activity | molecular function | HCCS |
| homogentisate 1,2-dioxygenase activity | molecular function | HGD |
| hormone activity | molecular function | CGA, FSHB, LHB, AMH, INHBA, ADM, INSL3, IGF2, GHRL, GNRH2, GNRH1, PRL, CGB3, TRH, LEP, GH1, IGF1, INSL6, OXT, INHA, IAPP, ANGPTL8, UTS2, FNDC5, FBN1, RLN2, ADIPOQ, NPY, CRH, UTS2B, CORT, TSHB, PMCH, CSHL1, GH2, MLN, UCN, RETNLB, STC2, METRN, COPA, CALCA, NMB, HAMP, CGB1, AVP, PTHLH, EDN1, CCK, SCT, CALCB, SST, UCN3, VGF, C1QTNF9, CSH1, NPPC, INHBC, INHBE, OSTN, UCN2, KL, CHGB, GAL, GPHA2, POMC, INS, EPO, PRLH, METRNL, TG, INS-IGF2, AGT, PYY, EDN3, RLN1, CSH2, THPO, GUCA2A, GALP |
| hormone binding | molecular function | ESR1, AMHR2, ESR2, GHSR, MTNR1A, ABHD2, NPR3, MCHR1, NPR1, UCN2, NPR2, CALR |
| hormone receptor binding | molecular function | SRC, NCOA6, NPPC, GPHA2 |
| hormone-sensitive lipase activity | molecular function | LIPE, ABHD2 |
| Hsp27 protein binding | molecular function | GMEB1 |
| Hsp70 protein binding | molecular function | CDK1, BAG6, PACRG, HIKESHI, DNAJC10, FICD, DNAJC8, ST13, DNAJB12, PPEF2, SNCA, DNAJB9, RPS3, NUP62, METTL21A, PRKN, TSC1, STUB1, HDAC8, NOD2, PPID, DNAJB14, DNAJC2, ERN1, CDKN1B, SACS, STIP1, DNAJB1, DNAJC18, SPN, CYP2E1, MVD, DNAJB2, FGF1 |
| Hsp90 protein binding | molecular function | AHR, HIF1A, KDR, PACRG, NPAS2, FKBP6, CHORDC1, PTGES3, SLC12A2, PPEF2, RPS3, NUP62, TSC1, STUB1, HDAC8, NOD2, PPID, AHSA1, CSNK2A1, ERN1, GBP1, KSR1, STIP1, PPP5C, HDAC6, ARNTL, CDK5, CYP2E1, TSC2, UNC45B, UNC45A, CDC37, EIF2AK3 |
| hyaluronan synthase activity | molecular function | HAS2, HAS3, HAS1 |
| hyaluronic acid binding | molecular function | CD44, C1QBP, CEMIP, HMMR, TNFAIP6, BCAN, ACAN, LAYN, HAPLN4, IMPG2, SUSD5, STAB1, LYVE1, HAPLN1, HYAL2, HAPLN3, HAPLN2, NCAN, STAB2 |
| hyaluronoglucuronidase activity | molecular function | HYAL3, HYAL2 |
| hyalurononglucosaminidase activity | molecular function | CD44, MGEA5, SPAM1, CEMIP, HYAL3, CEMIP2, HYAL2 |
| hydro-lyase activity | molecular function | CA5A, CA9, CA13, CA14, CA8, L3HYPDH, CA10, CA12, FAHD2B, FAHD2A, CA11, CA3, CA7, CYP2S1, CA4, CA1 |
| hydrogen ion channel activity | molecular function | NOX5, OTOP3, SLC4A11, OTOP1 |
| hydrogen ion transmembrane transporter activity | molecular function | ATP6V0A2, MT-ATP6, MT-ATP8, ATP6V1B1, ATP6V1B2, ATP5PB, DMAC2L, ATP5MC3, ATP5PF, ATP5PD, SLC36A1, ATP6V0E1, ATP5MC1, ATP5MC2, ATP5MG, ATP5ME, ATP6V0E2, ATP6V1C1, ATP6V0D1, ATP6V0B, ATP6V0A4, ATP6V1F, TCIRG1, ATP6V0C, ATP6V1C2, ATP6V0A1 |
| hydrolase activity | molecular function | USP9Y, DDX3Y, F10, MMP2, ACE, MMP9, RAG1, CASP1, CASP4, CASP6, MEST, OGG1, USP1, ERCC1, ABCB1, MTHFD1, CFTR, ERCC2, PON1, CDC25A, CDC25C, CASP3, CASP9, CASP8, USP26, CHD2, MGEA5, HEXA, KLK3, CTSD, HEXB, ABCC1, PTEN, LYZ, CLCA4, PON2, ASRGL1, PARK7, G6PC3, ADAMTS1, MAN1B1, ADAMTS5, SPO11, LTF, AMY2A, ACR, MMP12, PMS2, ASAH1, DDX4, PLAU, PLAT, MMP7, ARSA, ACP1, APEX1, EPHX2, SPAM1, ADAMTS20, LIPE, PTPN11, SHH, DUSP6, DPP8, PLCZ1, DROSHA, CHD7, DDX25, DICER1, DNM1L, PLA2G6, ELANE, ACPP, PGAM1, PSMA3, USP8, PAFAH1B2, ARG2, PGAM4, TDRD9, MOV10L1, RNASET2, MAN2B1, GBA, GAA, PLA2G2A, CPN1, GLB1, MPG, EXOSC10, SPAG1, PTPRJ, ENGASE, ADAT1, ACE2, CECR1, MALT1, PTPDC1, INPP4B, SYNJ1, PLCH2, PMPCB, POP4, FUCA1, ALPP, LTA4H, ATP6V1B1, PSMB1, MCM3, PSMB5, PSMC2, HINT1, HDAC4, SEC11A, LACTB, PDE4C, IDI1, CDKN3, AGBL2, AGBL4, ATAD2, MEIOB, ANKLE1, USP38, PSMA8, HELQ, DDX1, COPS5, USP47, RBBP8, PARL, SENP2, PNPLA8, ERAP1, MCM8, HPSE, FAN1, NUDT4B, DDX3X, PSMA7, NUDT21, RNGTT, RPP14, LIPF, MTHFD2, CPM, ATP6V1B2, PSMA1, PSMA2, |
| hydrolase activity, acting on acid anhydrides | molecular function | CHD7, SMARCA2, XRCC5, SUPV3L1, SMARCA4, CHD9, CHD6, CHD8 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | ERCC2, SMARCA5, HLTF, DHX29, RTEL1, SMARCA1, BLM, BRIP1, DDX11 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | molecular function | DPYSL2, DPYSL3, AMDHD1, DPYS, DPYSL5, NAAA, GDA, AMDHD2, DPYSL4, CAD, CRMP1 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides | molecular function | DPYSL2, DPYSL3, AMDHD1, DPYS, DPYSL5, CD101, DPYSL4, CAD, CRMP1 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | molecular function | KLK3, ASAH1, NTAQ1, ASPA, NIT1, BTD, UPB1, ACER3, VNN2, PIGL, VNN1, VNN3, ACY3, ACER1, ACER2 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines | molecular function | ARG2, DDAH1, AGMAT, DDAH2 |
| hydrolase activity, acting on ester bonds | molecular function | PGAP3, FAN1, LIPF, FEN1, TATDN1, OLAH, LIPJ, ASPA, ETHE1, LIPA, ERCC5, EXO1, NT5E, PTER, PGAP1, DBR1, FASN, ESD, C11orf54, PLA2G7, ACY3, TATDN2, AOAH, PLB1 |
| hydrolase activity, acting on glycosyl bonds | molecular function | OGG1, MGEA5, HEXA, HEXB, LYZ, MAN1B1, AMY2A, SPAM1, MAN2B1, GBA, GAA, GLB1, ENGASE, FUCA1, HPSE, CD38, NEIL1, GLA, MAN2A1, MGAM, SI, CEMIP, LYZL6, GUSB, HEXD, MACROD2, SMPD1, MAN2A2, GANC, HPSE2, NEIL2, DNPH1, MAN1A2, LCT, AGL, GALC, PGGHG, MANBA, NTHL1, MUTYH, LYZL1, LYZL2, TREH, HYAL3, NAGA, CTBS, FUCA2, CEMIP2, GBA2, HYAL2, SMPDL3B, NEU1, IDUA, GLB1L3, MAN2C1, GLB1L, MAN1C1, MAN1A1, MANEA, MANEAL, NEIL3, KL, NAGLU, NEU4, MACROD1, MYORG, MAN2B2, NEU2, MGAM2, GLB1L2 |
| hydrolase activity, hydrolyzing N-glycosyl compounds | molecular function | NEIL1, MAN2A1, MAN2A2, NEIL2, DNPH1, NEIL3, UNG |
| hydrolase activity, hydrolyzing O-glycosyl compounds | molecular function | HEXA, HEXB, MAN2B1, GAA, GLB1, GLA, ABHD10, MGAM, SI, GUSB, GBE1, HEXD, GANC, GNE, LCT, PGGHG, MANBA, NAGA, CTBS, GBA2, IDUA, GLB1L3, ADPRS, GLB1L, LCTL, KL, MYORG, MGAM2, GLB1L2 |
| hydroperoxy icosatetraenoate dehydratase activity | molecular function | PTGIS, ALOXE3, CYP2S1 |
| hydroperoxy icosatetraenoate isomerase activity | molecular function | CYP2J2, ALOXE3 |
| hydroxyacid-oxoacid transhydrogenase activity | molecular function | ADHFE1 |
| hydroxyacylglutathione hydrolase activity | molecular function | PNKD, HAGH |
| hydroxyapatite binding | molecular function | BGLAP, HACD1, STATH, CEMP1 |
| hydroxylysine kinase activity | molecular function | HYKK |
| hydroxymethyl-, formyl- and related transferase activity | molecular function | GART, MTFMT, ALDH1L1, ALDH1L2 |
| hydroxymethylbilane synthase activity | molecular function | HMBS |
| hydroxymethylglutaryl-CoA lyase activity | molecular function | HMGCL, HMGCLL1 |
| hydroxymethylglutaryl-CoA reductase (NADPH) activity | molecular function | HMGCR |
| hydroxymethylglutaryl-CoA reductase activity | molecular function | HMGCR |
| hydroxymethylglutaryl-CoA synthase activity | molecular function | HMGCS2, HMGCS1 |
| hydroxypyruvate isomerase activity | molecular function | HYI |
| hydroxypyruvate reductase activity | molecular function | GRHPR |
| hypoglycin A gamma-glutamyl transpeptidase activity | molecular function | GGT7, GGT1 |
| hypoxanthine phosphoribosyltransferase activity | molecular function | HPRT1, PRTFDC1 |
| hypoxia-inducible factor-asparagine oxygenase activity | molecular function | HIF1AN |
| I-SMAD binding | molecular function | CTNNB1, SMAD4, TGFB1I1, AXIN1, SMAD6, TGFBR1, SMAD2, AXIN2 |
| ICAM-3 receptor activity | molecular function | ITGB2, ITGAL |
| icosatetraenoic acid binding | molecular function | FABP3 |
| identical protein binding | molecular function | SOD1, EGFR, TNF, APOE, ESR1, TP53, INHBA, BCL2, TGFB3, MMP9, VEGFA, ATF3, FAS, CASP6, SOX10, FMR1, BAX, BAK1, BIRC5, SOD2, VWF, ERBB2, HSP90AA1, MAPK1, AKT1, STAT1, MDM2, CASP8, SERPINA1, ALB, GAPDH, HSPB1, APP, VIM, PARP1, MGST1, FGFR1, PRPS2, CBS, STAT3, LEPR, PTEN, LYZ, B2M, CSNK2B, PON2, DAZL, PARK7, RB1, IGF1R, IGF2R, HGF, KHDRBS1, CLDN11, FN1, RAF1, G6PD, PCNA, NCAM1, PPARG, ACTB, CDC42, 39326, UAP1, PICK1, DNM1L, ACPP, DYNLT1, PRDX1, TP63, RASSF1, THG1L, LDHA, ANXA4, SHTN1, TCERG1, PSTPIP1, HNRNPCL1, EED, OFD1, CLDN14, MLYCD, GLUD1, PRNP, LDHB, IAPP, ACADM, SKIL, PAM, CCNC, KIF5B, FUS, MATR3, VPS41, RAB9A, HDAC4, CLDN6, CLDN2, LACTB, HNRNPU, BEX3, EWSR1, IK, IKZF1, CAMK2B, CAMK2D, DMC1, SEPTIN2, PCM1, UGP2, USH1G, RNF20, RAB11FIP2, TRIM69, CEP57, SIAH1, KASH5, MNS1, M1AP, OPTN, RBBP8, CORO1B, DPY30, NIF3L1, NMNAT1, GRPEL1, TBK1, RTRAF, BTBD3, PSMA7, LECT2, NUDT21, JAK2, TYMS, PFKM, ADH5, DES, CD38, IMPA1, SRI, SHMT1, COIL, CEBPG, SNX16, CXCR4, MAX, PSMC6, ADARB1, GPSM2, CREB5, PTS, TLE1, STK3, DYRK1A, |
| iduronate-2-sulfatase activity | molecular function | IDS |
| IgA binding | molecular function | FCAR, AMBP |
| IgA receptor activity | molecular function | FCAR |
| IgE binding | molecular function | FCER1A, FCER1G, FCER2, MS4A2 |
| IgE receptor activity | molecular function | FCER1G |
| IgG binding | molecular function | FCGR3A, PIP, FCGR2B, UMOD, FCGR3B, FCGR2A, FCER1G, FCGRT, FCGR2C |
| IgM binding | molecular function | LILRA2, CD22 |
| IkappaB kinase activity | molecular function | IKBKE, IKBKB |
| IkappaB kinase complex binding | molecular function | MAP3K13 |
| imidazolonepropionase activity | molecular function | AMDHD1 |
| immunoglobulin binding | molecular function | VWF, MS4A1, CD4, HRG |
| immunoglobulin receptor activity | molecular function | CD200R1 |
| immunoglobulin receptor binding | molecular function | IGLL5, FGR, IGLL1, CLEC4D, FES |
| IMP cyclohydrolase activity | molecular function | ATIC |
| IMP dehydrogenase activity | molecular function | IMPDH2, IMPDH1 |
| importin-alpha family protein binding | molecular function | TPX2, CDADC1, DESI1, GOLGA2 |
| indanol dehydrogenase activity | molecular function | AKR1C3, AKR1B10, AKR1C1 |
| indoleamine 2,3-dioxygenase activity | molecular function | IDO2, IDO1 |
| inhibin binding | molecular function | INHBA, IGSF1, INHA, ACVR1B, ACVR2A |
| inhibitory extracellular ligand-gated ion channel activity | molecular function | GABRA2, GABRG2, GABRA5, GABRB2, GABRA4, GABRG1, GABRA1, GABRA3, GABRG3 |
| inorganic anion exchanger activity | molecular function | SLC4A7, SLC4A4, SLC4A2, SLC4A11, SLC4A8, SLC22A11, SLC4A1, SLC4A3, SLC22A8, SLC4A10, SLC4A9 |
| inorganic cation transmembrane transporter activity | molecular function | MMGT1, SLC39A1 |
| inorganic diphosphatase activity | molecular function | PPA2, LHPP, PPA1, PRUNE1 |
| inorganic diphosphate transmembrane transporter activity | molecular function | ANKH |
| inorganic phosphate transmembrane transporter activity | molecular function | SLC20A1, ANKH, SLC25A3, SLC20A2, SLC17A7 |
| inositol 1,3,4,5 tetrakisphosphate binding | molecular function | ASTN2, ADAP2, ITPR3, ADAP1, SYT2 |
| inositol 1,4,5 trisphosphate binding | molecular function | TRPC3, PLCL1, ITPR3, TRPC7, ITPR1, TRPC1, ITPR2, CYTH2, TRPC5, RPH3A, TRPC4, PLCL2 |
| inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels | molecular function | ITPR1 |
| inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | molecular function | ITPR3, ITPR1, ITPR2 |
| inositol bisphosphate phosphatase activity | molecular function | INPP5K |
| inositol diphosphate pentakisphosphate diphosphatase activity | molecular function | NUDT4B, NUDT4, NUDT3 |
| inositol diphosphate tetrakisphosphate diphosphatase activity | molecular function | NUDT4B, NUDT4, NUDT3 |
| inositol heptakisphosphate kinase activity | molecular function | PPIP5K1, PPIP5K2 |
| inositol hexakisphosphate 1-kinase activity | molecular function | PPIP5K1, IP6K3, PPIP5K2 |
| inositol hexakisphosphate 2-phosphatase activity | molecular function | MINPP1 |
| inositol hexakisphosphate 3-kinase activity | molecular function | PPIP5K1, IP6K3, PPIP5K2 |
| inositol hexakisphosphate 5-kinase activity | molecular function | PPIP5K1, IP6K3, PPIP5K2, IP6K2 |
| inositol hexakisphosphate 6-kinase activity | molecular function | IP6K3 |
| inositol hexakisphosphate binding | molecular function | ITPR3, GLE1, XPR1 |
| inositol hexakisphosphate kinase activity | molecular function | PPIP5K1, IP6K3, PPIP5K2, IP6K2 |
| inositol monophosphate 1-phosphatase activity | molecular function | IMPA1, INPP5F, IMPA2 |
| inositol monophosphate 3-phosphatase activity | molecular function | IMPA1, INPP5F, IMPA2 |
| inositol monophosphate 4-phosphatase activity | molecular function | IMPA1, INPP5F, IMPA2 |
| inositol monophosphate phosphatase activity | molecular function | IMPA1, INPP5F, IMPA2 |
| inositol pentakisphosphate 2-kinase activity | molecular function | IPPK |
| inositol phosphate phosphatase activity | molecular function | OCRL, MINPP1, INPP5B |
| inositol tetrakisphosphate 1-kinase activity | molecular function | ITPK1 |
| inositol tetrakisphosphate 3-kinase activity | molecular function | IPMK |
| inositol tetrakisphosphate 5-kinase activity | molecular function | IPMK |
| inositol tetrakisphosphate 6-kinase activity | molecular function | ITPK1, IPMK |
| inositol tetrakisphosphate kinase activity | molecular function | ITPKB, ITPKA, IPMK |
| inositol trisphosphate phosphatase activity | molecular function | INPP5K |
| inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity | molecular function | MINPP1 |
| inositol-1,3,4,5,6-pentakisphosphate kinase activity | molecular function | PPIP5K1, IP6K3, PPIP5K2 |
| inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | molecular function | PTEN, MINPP1 |
| inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity | molecular function | OCRL, INPP5A, INPP5K, INPP5D |
| inositol-1,3,4-trisphosphate 5-kinase activity | molecular function | ITPK1 |
| inositol-1,3,4-trisphosphate 6-kinase activity | molecular function | ITPK1 |
| inositol-1,4,5-trisphosphate 3-kinase activity | molecular function | ITPKB, ITPKA, IPMK |
| inositol-1,4,5-trisphosphate 5-phosphatase activity | molecular function | OCRL, INPP5A, INPP5K, INPP5B, INPP5D |
| inositol-1,4,5-trisphosphate 6-kinase activity | molecular function | IPMK |
| inositol-1,4-bisphosphate 1-phosphatase activity | molecular function | INPP1 |
| inositol-3-phosphate synthase activity | molecular function | ISYNA1 |
| inositol-hexakisphosphate phosphatase activity | molecular function | MINPP1 |
| inositol-polyphosphate 5-phosphatase activity | molecular function | OCRL, INPP5A, INPP5K, INPP5E, INPP5D |
| insulin binding | molecular function | INSR, IGF1R, PIK3R1, IDE, C2CD2L |
| insulin receptor binding | molecular function | INSL3, IGF2, IGF1, IGF1R, SRC, PTPN11, SORBS1, SNX2, PIK3R1, SHC1, SNX4, GRB10, PHIP, CCDC88A, IRS2, ENPP1, IRS1, PTPN1, IRS4, PDPK1, INS |
| insulin receptor substrate binding | molecular function | INSR, IGF1R, PIK3CA, PTPN11, JAK2, PIK3R1, GRB2, PRKCZ, PRKCD, INSRR |
| insulin-activated receptor activity | molecular function | INSR, INSRR |
| insulin-like growth factor binding | molecular function | IGFALS, IGF1R, IGF2R, CCN1, CCN2, CCN6, IGFBP1, IGFBP7, HTRA4, IGFBP4, KAZALD1, IGFBP2, CCN3, ESM1, IGFBP5, HTRA1, CCN4, HTRA3, CCN5, IGFBP6 |
| insulin-like growth factor I binding | molecular function | INSR, ITGAV, IGF1R, ITGA6, IGFBP1, ITGB3, ITGB4, LRP2, IGFBP4, IGFBP2, IGFBP5, IGFBP6 |
| insulin-like growth factor II binding | molecular function | INSR, IGF2R, IGFBP1, IGFBP4, IGFBP2, IGFBP5, IGFBP6 |
| insulin-like growth factor receptor binding | molecular function | GNAS, IGF2, IGF1, INSR, SOCS2, PIK3R1, SHC1, YWHAH, SOCS1, IRS1, YWHAG, CRK, INS |
| insulin-like growth factor-activated receptor activity | molecular function | IGF1R, IGF2R |
| integrin binding | molecular function | ICAM1, VWF, KDR, GSK3B, SEMA7A, ITGB1, ITGA5, ADAMTS5, IGF1, SRC, ITGA6, NRG1, FN1, CD9, NF2, TIMP2, CX3CL1, CCN1, CCN2, LGALS8, FERMT2, TNN, ANXA7, TNXB, CCN6, VCAM1, PXN, P4HB, ITGB5, PTN, FBN1, CD81, ADAM11, SPP1, UTRN, PTK2, CD226, JAM3, COL3A1, PTPN2, SYK, GPNMB, TSPAN8, FERMT1, MFGE8, FBLN5, TSPAN4, THBS1, ITGAM, EMP2, FBLN1, ACTN2, CD151, DST, TLN2, ANGPTL3, ISG15, HMGB1, ITGA2, ITGB6, COL4A3, ITGB1BP1, ECM2, ITGB3, ITGB4, CDH17, EDIL3, ACTN1, MMP14, ADAM2, CIB2, CXADR, ADAM9, ADAM22, F11R, S1PR2, LYN, TGFBI, ITGBL1, ITGB8, HSPG2, ADAM23, ITGAX, ITGB7, VTN, ITGB2, LAMB1, LCP1, CCN3, ILK, SFRP2, COL5A1, ESM1, ICAM5, NISCH, PLPP3, ICAM3, ACTN3, LAMB3, JAML, S1PR3, THY1, FGF2, PTPRZ1, THBS4, MYH9, JAM2, LAMA3, FRMD5, FERMT3, LAMA5, COMP, COL16A1, ADAMTS13, ITGB1BP2, ADAMTS8, TLN1, ITGA3, ACTN4, FCER2, CALR, CXCL12, LTBP4, CCN4, FGF1, CDH26, CCN5, ICAM4 |
| integrin binding involved in cell-matrix adhesion | molecular function | MADCAM1, EMILIN1 |
| interferon receptor activity | molecular function | IFNAR1, IL22RA1 |
| interferon-gamma binding | molecular function | KLHL20 |
| interferon-gamma receptor activity | molecular function | IFNGR1, IFNGR2 |
| interferon-gamma receptor binding | molecular function | IFNG |
| interleukin-1 binding | molecular function | IL1RAPL1, A2M, IL1R1, HAX1, NLRP7, TRIM16 |
| interleukin-1 receptor activity | molecular function | IL1R2, IL1R1, IL1RAP, IL1RL1, IL1RL2 |
| interleukin-1 receptor antagonist activity | molecular function | IL1RN, IL36RN, PXDN |
| interleukin-1 receptor binding | molecular function | IL1B, IL1RN, IL1A, IL1F10, IL1RAP, IL36RN, IL36G, TLR9, TLR5, TRIP6, IRAK4 |
| interleukin-1 Type I receptor antagonist activity | molecular function | IL1RN |
| interleukin-1 Type II receptor antagonist activity | molecular function | IL1RN |
| interleukin-1, Type I receptor binding | molecular function | IL1RN, TOLLIP |
| interleukin-1, type I, activating receptor activity | molecular function | IL1R1, IL1RL2 |
| interleukin-1, Type II receptor binding | molecular function | IL1RN, ERAP1 |
| interleukin-1, Type II, blocking receptor activity | molecular function | IL1R2 |
| interleukin-10 binding | molecular function | IL10RA |
| interleukin-10 receptor activity | molecular function | IL10RA, IL10RB |
| interleukin-10 receptor binding | molecular function | IL10 |
| interleukin-11 binding | molecular function | IL6ST, IL11RA |
| interleukin-11 receptor activity | molecular function | IL6ST, IL11RA |
| interleukin-11 receptor binding | molecular function | IL11 |
| interleukin-12 beta subunit binding | molecular function | IL12A |
| interleukin-12 receptor binding | molecular function | IL12A, JAK2, IL12RB1, IL23R |
| interleukin-13 receptor binding | molecular function | IL13 |
| interleukin-15 receptor activity | molecular function | IL15RA, IL2RB, IL2RG |
| interleukin-15 receptor binding | molecular function | SYK |
| interleukin-16 binding | molecular function | CD4 |
| interleukin-16 receptor activity | molecular function | CD4 |
| interleukin-17 receptor activity | molecular function | IL17RD, IL17REL, IL17RA |
| interleukin-17E receptor binding | molecular function | IL25 |
| interleukin-18 binding | molecular function | IL18BP |
| interleukin-18 receptor activity | molecular function | IL18RAP |
| interleukin-2 binding | molecular function | IL2RA, IL13RA1, CRLF2, IL2RB, IL2RG |
| interleukin-2 receptor activity | molecular function | IL2RA, IL2RB, IL2RG |
| interleukin-2 receptor binding | molecular function | IL2, IL21, ECM1, GATA3, TIMM50 |
| interleukin-20 binding | molecular function | IFNAR2, IL20RB, IL22RA1 |
| interleukin-20 receptor binding | molecular function | IL20 |
| interleukin-21 receptor activity | molecular function | IL21R |
| interleukin-22 binding | molecular function | IL22RA2 |
| interleukin-22 receptor activity | molecular function | IL22RA2 |
| interleukin-22 receptor binding | molecular function | IL20 |
| interleukin-23 receptor binding | molecular function | IL23A |
| interleukin-27 binding | molecular function | IL12A |
| interleukin-27 receptor activity | molecular function | IL6ST, IL27RA |
| interleukin-27 receptor binding | molecular function | IL27, EBI3 |
| interleukin-28 receptor binding | molecular function | IFNL1 |
| interleukin-3 receptor binding | molecular function | RNF41, IL3 |
| interleukin-33 binding | molecular function | IL1RL1 |
| interleukin-33 receptor activity | molecular function | IL1RAP, IL1RL1 |
| interleukin-4 receptor binding | molecular function | IL4, PIBF1, CD300LF |
| interleukin-5 receptor binding | molecular function | IL5, SDCBP |
| interleukin-6 binding | molecular function | IL6R, IL6ST |
| interleukin-6 receptor activity | molecular function | IL6R, IL6ST |
| interleukin-6 receptor binding | molecular function | IL6, IL6R, IL6ST, ERAP1, PYCARD, CNTF |
| interleukin-7 receptor activity | molecular function | IL7R, IL2RG |
| interleukin-7 receptor binding | molecular function | IL7, TSLP |
| interleukin-8 binding | molecular function | A2M, CXCR2, CXCR1 |
| interleukin-8 receptor activity | molecular function | CXCR2, CXCR1 |
| interleukin-8 receptor binding | molecular function | CXCL8, YARS1 |
| interleukin-9 receptor activity | molecular function | IL9R |
| Intermediate conductance calcium-activated potassium channel activity | molecular function | KCNN4 |
| intermediate filament binding | molecular function | SYNM, MTM1, EPPK1, NME2, PKP2, EVPL, NME1, EVPLL, NES |
| intracellular calcium activated chloride channel activity | molecular function | CLCA4, ANO6, TTYH2, ANO7, ANO9, NMUR2, TTYH1, ANO1, ANO2, ANO10, TTYH3, ANO8, ANO4 |
| intracellular cAMP-activated cation channel activity | molecular function | CNGA2, CNGB3, HCN2, HCN1, CNGB1, HCN4 |
| intracellular cGMP-activated cation channel activity | molecular function | CNGA2, CNGB3, AQP1, CNGB1 |
| intracellular cyclic nucleotide activated cation channel activity | molecular function | CNGB1 |
| intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity | molecular function | MCOLN1 |
| intracellular sodium activated potassium channel activity | molecular function | KCNT2, KCNT1 |
| intraciliary transport particle A binding | molecular function | IFTAP, TULP3, TUB |
| intraciliary transport particle B binding | molecular function | TTC30A, TTC26, KIFAP3 |
| intramolecular oxidoreductase activity, transposing C=C bonds | molecular function | ECI2, ECI1 |
| intramolecular transferase activity | molecular function | LSS |
| intramolecular transferase activity, phosphotransferases | molecular function | PGAM1, PGAM4, PGM3, PGM2L1, PGM1, BPGM, PGAM2, PGM5, PGM2 |
| intramolecular transferase activity, transferring hydroxy groups | molecular function | ALOXE3 |
| intronic transcription regulatory region sequence-specific DNA binding | molecular function | BCL6, NKX2-1 |
| inward rectifier potassium channel activity | molecular function | KCNJ10, KCNJ16, KCNH2, KCNJ15, KCNJ4, KCNJ2, KCNK1, KCNJ9, KCNJ8, KCNJ12, KCNJ1, KCNK6 |
| inward rectifier potassium channel inhibitor activity | molecular function | CAV1 |
| iodide peroxidase activity | molecular function | TPO, IYD |
| iodide transmembrane transporter activity | molecular function | SLC26A4, ANO1, SLC5A5 |
| ion antiporter activity involved in regulation of postsynaptic membrane potential | molecular function | SLC8A3, SLC8A1 |
| ion antiporter activity involved in regulation of presynaptic membrane potential | molecular function | ATP1A3 |
| ion binding | molecular function | RIDA |
| ion channel activity | molecular function | CATSPER1, CATSPER2, CLCN2, CATSPER4, CATSPER3, CACNA1S, GABRB1, ASIC4, CHRNA5, ASIC1, KCNH6, SCN11A, ASIC2, GABRA2, CHRNE, GRIN1, TRPC3, HTR3B, HTR3A, CACNA1E, CNGA2, KCNH3, KCNH4, KCNA4, KCNH2, KCND3, RYR1, RYR2, TMEM120A, CACNA1C, SLC9C1, HVCN1, KCND2, CHRNA2, GABRG2, GABRB3, KCND1, KCNQ3, GLRA3, TRPA1, CHRNB1, GABRA5, ITPR3, KCNG1, CACNA1A, KCNQ2, CHRNA7, SCNN1G, CHRND, CHRFAM7A, KCNG4, CHRNA10, TRPM3, TRPV2, GABRB2, GABRA4, KCNC4, GABRG1, CHRNA3, GRIA2, KCNB1, GRIN2C, SCN2A, TRPC7, GRIK3, GRIK5, CACNA1G, GABRP, SCN1A, GRIN2B, ITPR1, CACNA1I, GABRD, TRPC1, KCNV1, TPCN2, P2RX7, KCNF1, HCN2, HTR3E, P2RX6, KCNA6, GLRA1, ITPR2, CHRNA6, GRIN3A, KCNV2, KCNS3, MCUB, KCNG2, TRPC5, GRID2, HCN1, CACNA1H, KCNA2, GABRR2, GRIA3, GRIK4, TRPC4, KCNK3, CHRNG, GABRA1, KCNC1, KCNQ4, CACNA1D, GRIN2A, TRPM4, KCNC2, P2RX4, GRIN3B, CHRNB2, GABRA3, SCN4A, CHRNA4, ZACN, P2RX5, GABRQ, HCN4, KCNA3, GRIA1, P2RX3, KCNA1, TRPM1, TRPV3, TRPM5, GRID1, TRPM2, CACNA1B, SCN5A, GJD3, KCNH8, P2RX2, TMEM120B, GABRR3, GRIN2D, GRIK1, KCNMA1, GR |
| ion channel binding | molecular function | FMR1, BAK1, HSP90AA1, CIB1, CTNNB1, YES1, SRC, YWHAQ, SUMO1, PKD1, VDAC1, GOPC, PRNP, ATP2A2, FGF12, CAMK2D, KCNAB1, SRI, PACS1, CRBN, RIMS2, TCAP, ANK3, NPTN, YWHAH, PPP1R9B, LRRC26, RIMS1, TRDN, PHPT1, KCND3, FXYD1, FHL1, RYR2, RANGRF, CHERP, PANX1, YWHAZ, PKD2, HERPUD1, TCAF2, DIAPH1, ACTN2, CAV3, SCN1B, AP2M1, KCNG4, ABCC9, CALM1, CALM2, CALM3, LRRC52, PRKCSH, YWHAE, ANK2, PDE4B, DLG1, KCNB1, AKAP9, ACTN1, GPD1L, NEDD4L, SLC8A1, LYN, FKBP1B, PDE4D, KCNE4, TRAPPC2, ASPH, HOMER1, TRPC1, ATP2A3, PKP2, PPP1R9A, TCAF1, HTT, ID2, ITPR2, CDH5, PYCARD, KCNAB3, KCNE1, ACTN3, USP10, KCNIP2, HRC, KCNC1, S100A10, KCNC2, RIMS3, CABP4, KCNAB2, SNTA1, SCN4B, PACS2, CBARP, KCNIP3, ACTN4, ABCC8, SCN5A, SH3GL1, KCNH5, SCN10A, HAP1, LRRK2, LRRC55, RIMS4, SCN3B, KCNE3, CAV1, AKAP6 |
| ion channel inhibitor activity | molecular function | RACK1, LYNX1, PDZD3, KCNV1 |
| ion channel regulator activity | molecular function | FXYD1, FXYD4, FXYD3, FXYD2, FXYD6, FXYD7 |
| ion gated channel activity | molecular function | ASIC1, ASIC2 |
| ion transmembrane transporter activity | molecular function | GJA1, PLP2, SFXN1, S100A6, TRPV2, ATP11B, SFXN3, LASP1, SFXN2, SFXN5 |
| ion transmembrane transporter activity, phosphorylative mechanism | molecular function | ABCC4 |
| ionotropic glutamate receptor activity | molecular function | GRIN1, GRIA2, GRIN2C, GRIK3, GRIK5, GRIN2B, GRIN3A, GRID2, GRIA3, GRIK4, GRIN2A, GRIN3B, GRIA1, GRID1, GRIN2D, GRIK1, GRIK2 |
| ionotropic glutamate receptor binding | molecular function | GNAS, GSK3B, CTNNB1, FUS, CANX, RAPSN, NSF, CACNG2, RAB4A, CACNG3, NEDD4, SHANK2, SQSTM1, FLOT1, CDK5R1, DLG4, NETO2, CACNG4, OPHN1, DLG3, DRD2, SHANK1, SHISA7, SHISA6, NETO1 |
| iron chaperone activity | molecular function | FXN |
| iron ion binding | molecular function | CYP1A1, CYP19A1, NOS3, PLOD1, CYP24A1, CYP17A1, CYP1A2, CYP2B6, CYP11A1, CYP11B1, LTF, XDH, CYP21A2, CYP11B2, CYP1B1, CYP26B1, MT-CO1, SCD, HAAO, ISCA2, P3H3, DOHH, PAH, CYP2J2, NFU1, FTL, CYP4A11, CYP4F3, FBXL5, CYP20A1, PPEF2, CYP2R1, AGMO, PHF2, SC5D, FTH1, RIOX1, ETHE1, CYP2A7, ACO2, CYP2C8, PLOD2, FDX1, CYP4F8, MSMO1, CYP26A1, CH25H, CYP4B1, CYP2A6, CYP2C19, CYP4F22, P4HA3, CYP8B1, PPEF1, P4HA1, CDO1, SCD5, FTMT, HBZ, TPH1, PHF8, CYP27B1, PTGIS, OGFOD3, FA2H, ADI1, ALOX5, CYP3A5, TPH2, TET1, ISCU, CYP2C18, EGLN1, ALOXE3, CYP4F12, CYP51A1, PLOD3, TH, HBQ1, AOX1, FAXDC2, EGLN2, TYW5, P3H1, ALKBH8, TMLHE, CYP2E1, TBXAS1, CYP4F2, CYP4Z1, CYP4X1, OGFOD1, ALOX15B, P4HA2, HBA1, CYP26C1, CYP46A1, ALOX12B, MELTF, CYP2D6, CYP2S1, FTHL17, CYP2D7, CALR, OGFOD2, CYP2W1, CYGB, CYP4F11, CYP2C9, CYP3A43 |
| iron ion transmembrane transporter activity | molecular function | SLC39A8, SLC25A37, SLC25A28, SLC11A1, SLC40A1, TTYH1, MCOLN1, SLC39A14 |
| iron ion transmembrane transporter inhibitor activity | molecular function | HAMP |
| iron-cytochrome-c reductase activity | molecular function | POR |
| iron-responsive element binding | molecular function | IREB2, ACO1 |
| iron-sulfur cluster binding | molecular function | ERCC2, XDH, SDHB, GLRX5, ISCA2, NUBPL, REV3L, UQCRFS1, PRIM2, ISCA1, EXO5, NFU1, ETFDH, CDK5RAP1, FECH, NUBP1, CIAPIN1, RPS3, NDUFS2, IREB2, GLRX2, ACO2, LIAS, RSAD2, GLRX3, FDX1, NDUFS1, NTHL1, RTEL1, MUTYH, NDUFV2, NUBP2, ISCU, CISD1, ABAT, NFS1, FDX2, RFESD, RSAD1, NDUFS8, KIF4A, PPAT, AOX1, POLE, DPYD, BRIP1, CIAO3, ELP3, AIFM3, ACO1, DDX11, POLD1, CISD3, KIF4B, CDKAL1, TYW1B, TYW1, NDUFS7, POLA1, BOLA2 |
| ISG15 activating enzyme activity | molecular function | UBA7 |
| ISG15 transferase activity | molecular function | UBE2E2, UBE2L6, UBE2E1, HERC5 |
| ISG15-specific protease activity | molecular function | USP43 |
| isocitrate dehydrogenase (NAD+) activity | molecular function | IDH3B, IDH3G, IDH3A |
| isocitrate dehydrogenase (NADP+) activity | molecular function | IDH1, IDH2 |
| isocitrate dehydrogenase activity | molecular function | IDH1, IDH2 |
| isoleucine-tRNA ligase activity | molecular function | IARS1, IARS2 |
| isomerase activity | molecular function | HSD17B4, FKBP4, HSD3B1, HSD3B2, SPO11, MIF, PDIA3, PTGDS, APOA1BP, TOP2A, PGAM1, PGAM4, TOP1, FKBP5, IDI1, PPIL4, PPIL3, DSE, DKC1, PPIB, CYP2J2, ECH1, PTGES3, FKBP14, PGM3, PIN1, PGM2L1, RPUSD4, MCEE, AMACR, KATNA1, P4HB, LSS, FKBP7, PGM1, PDIA6, RPUSD3, CRELD2, FKBP10, CRELD1, FKBP3, TRUB1, FUOM, GSTA1, PDIA4, EBP, PUSL1, ECI2, NKTR, MPI, RPIA, PPID, PUS10, DSEL, PMM1, GLCE, BPGM, HMGCS1, PTGES2, PGAM2, ISYNA1, PPIF, GALE, PTGES, TPI1, PPIG, ITPK1, RPE, MRI1, PUS3, GPI, PTGIS, GALM, GSTZ1, FKBP1B, TOP2B, FKBP11, PIN4, ENOSF1, PPWD1, PGM2, TSTA3, ALOXE3, PPIH, FKBP2, PPIE, FKBP8, PUS7L, HPGDS, TRUB2, TOP3B, TBXAS1, ECI1, RENBP, PDIA5, SRR, ALOX12B, CYP2S1, PDIA2, THAP4, PUS7, PPIA, RPE65, KATNAL2, TOP1MT, SPAST, DCT, PPIC, HYI, TMX3 |
| isopentenyl-diphosphate delta-isomerase activity | molecular function | IDI1 |
| isoprenoid binding | molecular function | PGGT1B |
| isovaleryl-CoA dehydrogenase activity | molecular function | IVD |
| itaconyl-CoA hydratase activity | molecular function | AUH |
| ITP binding | molecular function | NUDT16 |
| JAK pathway signal transduction adaptor activity | molecular function | SOCS2 |
| JUN kinase activity | molecular function | MAPK8, MAPK9, MAPK10 |
| JUN kinase binding | molecular function | GSTP1, KIF5B, MAPK8IP1, PTK2, RNF13, MAD2L2, DUSP10 |
| JUN kinase kinase activity | molecular function | MAP2K4, MAP2K7 |
| JUN kinase kinase kinase activity | molecular function | MAP3K13, MAP3K12, MAP3K9, MAP3K10 |
| JUN kinase phosphatase activity | molecular function | DUSP19 |
| K11-linked polyubiquitin modification-dependent protein binding | molecular function | MINDY2 |
| K48-linked polyubiquitin modification-dependent protein binding | molecular function | MINDY1, UFD1, IKBKE, ZFAND2B, MINDY2, UBQLN4, UBXN1 |
| K6-linked polyubiquitin modification-dependent protein binding | molecular function | MINDY2, UBXN1 |
| K63-linked polyubiquitin modification-dependent protein binding | molecular function | OPTN, UIMC1, RNF168, FAAP20, OTUD7A, IKBKE, SQSTM1, WDR81, IKBKG, TAB2, ZRANB3, PRPF8, MINDY2, RNF169, ZRANB1, TNIP2, SPRTN, OTUD7B, PARP10, ATRIP, ZBTB1 |
| kainate selective glutamate receptor activity | molecular function | GRIK3, GRIK5, GRIK4, GRIK1, GRIK2 |
| kappa-type opioid receptor binding | molecular function | IL2 |
| KDEL sequence binding | molecular function | KDELR2, KDELR3, KDELR1 |
| keratin filament binding | molecular function | VIM, EPPK1, FAM83H, KRT74, KRT14 |
| ketohexokinase activity | molecular function | KHK |
| ketoreductase activity | molecular function | AKR1C3 |
| ketosteroid monooxygenase activity | molecular function | AKR1C3, AKR1C2, AKR1D1, AKR1C1, AKR1C4 |
| kinase activator activity | molecular function | IL2, MALT1, LAMTOR3, BCL10, TAB1, MOB1B, ITSN1 |
| kinase activity | molecular function | EGFR, AMHR2, TSSK4, TSSK6, AURKC, ERBB2, CDK1, CCNB1, FLT1, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, KDR, GSK3B, ATM, PANK2, FGFR1, PRPS2, CSNK2A2, MTOR, BRSK2, INSR, PGK2, YES1, IGF1R, KIT, SRC, CHKA, PIK3CA, MAPK8, ATR, BMPR2, LMTK2, CDC7, PDXK, RAF1, MAK, CLK3, CDK9, PGK1, NTRK1, DDR1, CAMK4, MAST2, PPIP5K1, CKM, LIMK2, DMPK, MAPK14, PRPS1L1, RYK, ROR1, CAMK2B, CAMK2D, GK2, PDK4, DGKK, ADPGK, WNK3, NMRK1, TBK1, MOK, NME7, JAK2, PFKM, GK, GRK5, CSNK1A1, STK3, DYRK1A, PDK3, NADK2, NEK8, SPHK2, STK36, PLK2, MAP3K4, EEF2K, PIK3C2A, DYRK3, KALRN, MARK3, SEPHS1, CDK7, DGKE, AK2, ADK, MAP4K2, MAPK6, SGMS2, COQ8A, NEK1, TRIB3, RPS6KB2, CIT, FAM20B, CDK14, CKMT2, ACVR1B, PFKP, STK4, MAPK11, MARK2, ADCK2, MAP4K1, FGGY, WNK4, STK31, ALK, PIKFYVE, DYRK1B, MAP3K7, NADK, RPS6KB1, PRKCH, LTK, MAPK4, CSNK1E, IRAK1, TLK2, UHMK1, COQ8B, ALPK1, PASK, SEPHS2, EIF2AK1, MAP3K20, STK17A, BAZ1B, AK6, RPS6KL1, STK25, BUB1, BUB1B, STK17B, CCL3, PRKACB, EPHB2, TIE1, ACVR1, PTK2, PMVK, PRKD1, STK38, TKFC, CAMK1D, MASTL, CDK |
| kinase binding | molecular function | FAS, ITGB1, CTNNB1, PARK7, RB1, SRC, NTRK1, LDHA, PER3, EEF1A1, CAB39, PFKM, PPP2R5A, PER1, MYOM2, BCL10, BTG1, TNS2, LAPTM4B, RASGRP3, NIN, PPP1R9B, ERRFI1, DAB2IP, RPS3, MIDN, PRKN, WDCP, ABI2, STUB1, OPA1, KIF1B, EMP2, HPCA, SGO1, MOB1B, WWC1, PIP5K1A, PFKFB2, ATP1A4, TAX1BP1, CDC6, PTPN22, GADD45A, PARP16, MOB4, CNOT9, JAKMIP2, ITGB1BP1, SP100, PRDX3, DLG1, TIAM1, TOLLIP, STRADA, WWC3, PRKCD, CRY1, PARP6, JAKMIP3, TTC28, CHP1, CARD16, DGKH, DLG4, BARD1, HTT, TRADD, DLG3, PLG, CEACAM1, PARP8, PDE8A, BCAR3, LRRC14, CD160, PFKL, POLR2A, IGSF9B, MYOM1, DGKQ, DGKD, AURKB, DLG2, TRIP6, CDC37, SIT1 |
| kinase inhibitor activity | molecular function | WARS1, SOCS1, LRP6, RHOH, AHSG |
| kinase regulator activity | molecular function | GSTP1, BCCIP, GSKIP, AKAP11 |
| kinesin binding | molecular function | ACTB, SHTN1, IFT88, TRAK2, RAB29, ARHGEF10, AP1AR, KLC2, SPTBN5, MAPK8IP1, NEFH, SNCA, KTN1, KIFAP3, AP1G1, NUP62, FAM83D, DISC1, PRC1, KIF1B, DCDC2, TTBK2, KIF5A, PIFO, DCP1A, TOR1B, CLSTN1, KCNA2, KCNC1, KLC3, NEK6, MAPK8IP2, KIF18B, PLEKHM2, CROCC, ATCAY |
| kinetochore binding | molecular function | CENPE, SPDL1, MAD1L1, TTK, CLASP1, CENPH |
| kininogen binding | molecular function | C1QBP, CTSV |
| kisspeptin receptor binding | molecular function | KISS1 |
| kringle domain binding | molecular function | CLEC3B |
| kynureninase activity | molecular function | KYNU |
| kynurenine-oxoglutarate transaminase activity | molecular function | KYAT1, AADAT, GOT2 |
| L-alanine transmembrane transporter activity | molecular function | SLC36A4, SLC38A7, SLC36A1, SLC1A4, SLC36A2, SLC36A3, SLC38A3 |
| L-alanine:2-oxoglutarate aminotransferase activity | molecular function | GPT, GPT2 |
| L-allo-threonine aldolase activity | molecular function | SHMT1, SHMT2 |
| L-amino acid transmembrane transporter activity | molecular function | SLC7A5, SLC38A7, SLC7A6, SLC38A1, SLC7A8, SLC7A9, SLC7A7, SLC43A1, SLC7A10, SLC43A2 |
| L-arginine transmembrane transporter activity | molecular function | SLC38A9, SLC7A3, SLC7A1, SLC7A2 |
| L-ascorbate:sodium symporter activity | molecular function | SLC23A1, SLC23A2 |
| L-ascorbic acid binding | molecular function | PLOD1, PAM, P3H3, PHYH, PLOD2, P4HA3, P4HA1, OGFOD3, EGLN1, ALKBH3, PLOD3, EGLN2, P3H1, OGFOD1, P4HA2, DBH, OGFOD2 |
| L-ascorbic acid transmembrane transporter activity | molecular function | SLC23A1, SLC23A2 |
| L-asparagine transmembrane transporter activity | molecular function | SLC38A7, SLC38A5, SLC38A3 |
| L-aspartate transmembrane transporter activity | molecular function | SLC13A3, SLC1A5, SLC38A7, SLC25A13, SLC25A18, SLC25A22, SLC1A4, SLC1A6, SLC25A12 |
| L-aspartate:2-oxoglutarate aminotransferase activity | molecular function | GOT1L1, GOT1, GOT2 |
| L-cysteine desulfhydrase activity | molecular function | CTH |
| L-cysteine:2-oxoglutarate aminotransferase activity | molecular function | GOT1 |
| L-cystine L-cysteine-lyase (deaminating) | molecular function | CTH |
| L-cystine transmembrane transporter activity | molecular function | CTNS, SLC1A4, SLC3A1, SLC7A9 |
| L-DOPA binding | molecular function | GPR143 |
| L-dopa decarboxylase activator activity | molecular function | PARK7 |
| L-dopa decarboxylase activity | molecular function | DDC |
| L-dopa O-methyltransferase activity | molecular function | LRTOMT |
| L-DOPA receptor activity | molecular function | GPR143 |
| L-fuconate dehydratase activity | molecular function | ENOSF1 |
| L-fucose mutarotase activity | molecular function | FUOM |
| L-glucuronate reductase activity | molecular function | AKR1A1 |
| L-glutamate transmembrane transporter activity | molecular function | SLC38A7, SLC25A13, SLC25A18, SLC25A22, SLC1A2, SLC1A3, SLC17A6, SLC1A6, SLC1A7, SLC25A12, SLC17A7 |
| L-glutamine aminotransferase activity | molecular function | KYAT1 |
| L-glutamine transmembrane transporter activity | molecular function | SLC1A5, SLC38A7, SLC38A6, SLC38A1, SLC1A4, SLC38A2, SLC38A5, SLC38A3 |
| L-gulonate 3-dehydrogenase activity | molecular function | CRYL1 |
| L-histidine transmembrane transporter activity | molecular function | SLC15A4, SLC38A7, SLC7A1, SLC38A5, SLC38A3 |
| L-hydroxyproline transmembrane transporter activity | molecular function | SLC1A4 |
| L-iditol 2-dehydrogenase activity | molecular function | SORD |
| L-iduronidase activity | molecular function | IDUA |
| L-isoleucine transaminase activity | molecular function | BCAT1, BCAT2 |
| L-lactate dehydrogenase activity | molecular function | LDHC, LDHA, LDHB, LDHAL6B, HAO2, HAO1 |
| L-leucine transaminase activity | molecular function | BCAT1, BCAT2 |
| L-leucine transmembrane transporter activity | molecular function | SLC38A9, SLC38A7 |
| L-lysine transmembrane transporter activity | molecular function | SLC7A3, SLC66A1, SLC7A1, SLC7A2 |
| L-malate dehydrogenase activity | molecular function | MDH2, MDH1, MDH1B, PHGDH |
| L-methionine transmembrane transporter activity | molecular function | SLC38A7 |
| L-methionine-(R)-S-oxide reductase activity | molecular function | MSRB3, MSRB2, MSRB1 |
| L-methionine-(S)-S-oxide reductase activity | molecular function | MSRA |
| L-ornithine transmembrane transporter activity | molecular function | SLC7A3, SLC7A1, SLC25A15, SLC25A2, SLC7A2 |
| L-pipecolate oxidase activity | molecular function | PIPOX |
| L-proline transmembrane transporter activity | molecular function | SLC36A4, SLC36A1, SLC1A4, SLC36A2, SLC36A3, SLC6A7 |
| L-serine ammonia-lyase activity | molecular function | SDSL, SDS, SRR |
| L-serine transmembrane transporter activity | molecular function | SLC1A5, SLC38A7, SLC1A4, SFXN1, SLC38A2, SLC7A10, SLC38A5 |
| L-serine-phosphatidylethanolamine phosphatidyltransferase activity | molecular function | PTDSS2, PTDSS1 |
| L-seryl-tRNA(Sec) kinase activity | molecular function | PSTK |
| L-threonine ammonia-lyase activity | molecular function | SDSL, SDS |
| L-threonine transmembrane transporter activity | molecular function | SLC1A4 |
| L-tryptophan transmembrane transporter activity | molecular function | SLC36A4 |
| L-tyrosine transmembrane transporter activity | molecular function | OCA2 |
| L-tyrosine:2-oxoglutarate aminotransferase activity | molecular function | TAT |
| L-valine transaminase activity | molecular function | BCAT1, BCAT2 |
| L-xylulose reductase (NADP+) activity | molecular function | DCXR |
| L27 domain binding | molecular function | LIN7C, LIN7A, DLG1, LIN7B |
| lactase activity | molecular function | LCT |
| lactate dehydrogenase activity | molecular function | LDHA |
| lactate transmembrane transporter activity | molecular function | SLC16A7, SLC5A8, SLC5A12, SLC16A8, SLC16A1 |
| lactose binding | molecular function | LGALS12 |
| lactose synthase activity | molecular function | B4GALT2, B4GALT1, LALBA |
| lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity | molecular function | B3GNT5 |
| lactosylceramide 4-alpha-galactosyltransferase activity | molecular function | A4GALT |
| lactoylglutathione lyase activity | molecular function | GLO1 |
| lamin binding | molecular function | PRNP, LBR, NARF, TOR1AIP1, BNIP3L, MLIP, TMPO, IFI27, SUN2, TMEM201, SYNE1, AKAP8L |
| laminin binding | molecular function | ITGB1, ECM1, BCAM, THBS1, ITGA2, ADAM9, PLEKHA2, RPSA, CTSS, TINAGL1, LYPD3, ITGA9, DAG1, GPC1, SSC5D, AGRN, ITGA3, LYPD5 |
| laminin receptor activity | molecular function | BCAM, RPSA |
| laminin-1 binding | molecular function | SHH, NTN4, DAG1, SLIT2 |
| lanosterol synthase activity | molecular function | LSS |
| large conductance calcium-activated potassium channel activity | molecular function | KCNMA1 |
| large ribosomal subunit rRNA binding | molecular function | RPLP0, MRPL11, RPL12, RPL23 |
| latrotoxin receptor activity | molecular function | ADGRL1, ADGRL2 |
| LBD domain binding | molecular function | CITED1, SPON1, CITED2, PROX1 |
| leak channel activity | molecular function | PANX1, RHAG, NALCN |
| left-handed Z-DNA binding | molecular function | ZBP1 |
| leptin receptor activity | molecular function | LEPR |
| leptin receptor binding | molecular function | SNX2, SNX4 |
| leptomycin B binding | molecular function | ID3 |
| leucine binding | molecular function | UBR2, GLUD1, SESN3, GLUD2, UBR1, SESN2 |
| leucine zipper domain binding | molecular function | DDIT3, PAWR, MRTFA, ATF4, ERC1, AATF, NRL, PMF1, CRX, CDC5L |
| leucine-tRNA ligase activity | molecular function | LARS1, LARS2 |
| leukemia inhibitory factor receptor activity | molecular function | IL6ST, LIFR |
| leukemia inhibitory factor receptor binding | molecular function | LIF, CTF1 |
| leukotriene B4 receptor activity | molecular function | LTB4R, LTB4R2 |
| leukotriene C4 gamma-glutamyl transferase activity | molecular function | GGT7, GGT1 |
| leukotriene receptor activity | molecular function | CYSLTR1, LTB4R, LTB4R2 |
| leukotriene-A4 hydrolase activity | molecular function | LTA4H |
| leukotriene-B4 20-monooxygenase activity | molecular function | CYP4A11, CYP4F3, CYP4F8, CYP4F12, CYP4F2, CYP4F11 |
| leukotriene-C(4) hydrolase | molecular function | GGT1 |
| leukotriene-C4 synthase activity | molecular function | ALOX5AP, MGST3, MGST2, GSTM4, LTC4S |
| ligand-activated transcription factor activity | molecular function | RORA, RORC |
| ligand-dependent nuclear receptor binding | molecular function | NCOA2, TADA3, TRIM24, ISL1, SLC30A9, TACC1, SMARCE1, NCOA3, PPARGC1A, SMARCD3, NR1H4, BAZ2A, C1D, NCOA1, UBA3, NCOR2, TRIP4, ARID1A, JUND, PROX1 |
| ligand-dependent nuclear receptor transcription coactivator activity | molecular function | NCOA2, PPARG, TADA3, MED4, SLC30A9, TSG101, ENY2, CARM1, WDR77, CALCOCO1, NCOA6, BUD31, ZMIZ1, NCOA3, DCAF6, HELZ2, PPARGC1A, SS18, SMARCD3, CCAR1, PSMC3IP, USP22, MED14, ACTN2, MED13, PRKCB, SRA1, CCDC62, CCAR2, ACTN1, NCOA1, RBM14, SFR1, MED30, ZCCHC12, TRERF1, MED12, PKN1, THRAP3, FGF2, PPRC1, PPARGC1B, ACTN4, MED24, ZMIZ2, NCOA7 |
| ligand-gated calcium channel activity | molecular function | P2RX4, MCOLN1, TRPM2 |
| ligand-gated ion channel activity | molecular function | ANXA6, GABRB1, CHRNA5, GRIN1, HTR3B, HTR3A, CHRNB1, CHRND, CHRNA3, GRIA2, GRIN2C, GRIK3, GRIK5, GRIN2B, GRIN3A, GRID2, GRIA3, GRIK4, GRIN2A, GRIN3B, CHRNB2, CHRNA4, CNGB1, ZACN, GRIA1, GRID1, P2RX2, GRIN2D, GRIK1, GRIK2, CHRNB4, TRPV1 |
| ligand-gated ion channel activity involved in regulation of presynaptic membrane potential | molecular function | GRIK3, GRIK2 |
| ligand-gated sodium channel activity | molecular function | ASIC1, ASIC2, SCNN1G, SCNN1A, SCNN1D, SHROOM2, SCNN1B, ASIC3, TPCN1 |
| ligase activity | molecular function | RAG1, BRCA1, LIG4, MTHFD1, MDM2, UBR2, RNF114, RNF8, FARS2, AACS, PCCA, GMPS, KARS1, ACSS3, NARS1, GART, MARS1, EPRS1, CPS1, IARS1, TRIM25, BTRC, RTCA, PAICS, ADSS2, SUCLG1, YARS1, NADSYN1, SUCLA2, RTCB, HARS1, GCLC, CARS1, RARS1, DARS2, TTLL7, SARS2, IARS2, ACSL3, ASS1, ASNS, WARS1, ACSL1, HARS2, ACSBG2, SLC27A3, MTHFD1L, TTLL1, CTPS1, TARS1, UBA7, MCCC1, CARS2, SLC27A5, PC, AARS1, MTHFS, AARS2, SLC27A1, SUCLG2, AASDH, LARS1, GLUL, NAPRT, ACSM2A, DPH6, TTLL6, TTL, TTLL2, SARS1, TTLL4, ADSS1, ACSL5, RIMKLB, GARS1, TTLL11, UBA3, XRCC4, TTLL9, PARS2, MCCC2, ACSS1, ACSL4, PCCB, RARS2, ACSM5, PPCS, FARSB, UBA6, SLC27A2, LIG1, ACSM3, RIMKLA, ACACA, NARS2, TARS2, VARS1, QARS1, LIG3, QRSL1, FPGS, LARS2, GATB, FARSA, TARS3, HLCS, SLC27A4, ACACB, PFAS, ACSF3, ACSBG1, TTLL3, CAD, ACSM1, ACSF2, GATC, EARS2, SAE1, ACSS2, UCHL1, VARS2, CTPS2 |
| ligase activity, forming carbon-nitrogen bonds | molecular function | RIMKLB, RIMKLA |
| ligase activity, forming phosphoric ester bonds | molecular function | RTCB |
| ligase regulator activity | molecular function | CAPN3 |
| LIM domain binding | molecular function | ACTN2, RIPK2, LDB1, LDB2, KAT14, TLN1, RPH3AL |
| linear malto-oligosaccharide phosphorylase activity | molecular function | PYGL, PYGB, PYGM |
| linear polyubiquitin binding | molecular function | IKBKG |
| linoleate 13S-lipoxygenase activity | molecular function | ALOX15B |
| linoleate 9S-lipoxygenase activity | molecular function | ALOX12B |
| linoleic acid binding | molecular function | PPARD |
| linoleic acid epoxygenase activity | molecular function | CYP2J2 |
| linoleoyl-CoA desaturase activity | molecular function | FADS1, FADS2 |
| lipase activator activity | molecular function | APOA5 |
| lipase activity | molecular function | LIPE, LPL, LYPLA1, LIPG, LIPA, AADAC, LIPC, LIPH, DAGLB, PNLIPRP2, PNLIPRP1, MGLL, PLA1A, PLB1, PNLIP, LDAH |
| lipase binding | molecular function | APOB, FAF2, GPIHBP1, LRPAP1, APOA5 |
| lipase inhibitor activity | molecular function | FAF2, APOA1, APOC1, APOC3 |
| lipid antigen binding | molecular function | PSAP |
| lipid binding | molecular function | NR5A2, APOE, ESR1, SHBG, PGR, AR, PTGS1, PTGS2, BAX, NR5A1, ESR2, APOB, C3, ALB, NR3C1, SULT1E1, PTEN, BAD, CYP21A2, DNM1L, STARD9, ANXA6, SNX3, PITPNB, GRAMD1C, LPAR4, PGRMC2, ERLIN1, LIPF, SCP2, GRK5, SNX16, PAQR6, SNX19, FERMT2, OSBPL1A, OGT, DBI, CD55, ATP5MC3, PAQR9, PDZD8, FNBP1, SNX7, SNX6, CYTH3, SNX2, COQ9, APOL3, MARK2, PAQR8, SNX27, RTN4R, EPN3, SH3GLB1, CD1C, STAR, CD81, PITPNA, PPARD, WASHC2A, C2CD5, TEX2, OMA1, PASK, SH3GL2, CHMP4A, SNX10, FCHSD2, SNX4, PEBP1, HDLBP, FABP5, FNBP1L, VPS36, DLC1, RUFY1, ARHGAP9, PLEKHA1, DGKB, MANF, STARD6, GPR119, DENND1A, SH3GL3, PITPNM3, PLEKHA3, ARHGAP35, PGRMC1, RASGRP1, ARHGEF5, SNX20, AMER3, NOXO1, OSBPL5, SAP30L, ATP13A2, SNX8, AP2A2, FABP3, ATP5MC1, PSAP, RBP5, ATP5MC2, GPIHBP1, SNX21, RPS6KC1, STOML2, EPDR1, OPA1, PMP2, RBP1, DGKA, FABP6, UNC119, CLINT1, RASGRP2, KIF16B, APOLD1, OSBPL11, OSBPL8, OSBPL2, STARD7, SEC14L3, PCTP, SNX5, IQSEC1, AP2M1, PLEKHA4, CADPS, PACSIN2, SNX24, SEC14L2, APOD, TEC, DGKG, GRB7, MELK, BPIFC, BPIFB1, PARD3, BPIFA2, PRAM1, AP |
| lipid kinase activity | molecular function | SPHK2, DGKZ, CERK, PIK3C2B, AGK |
| lipid phosphatase activity | molecular function | EPHX2, PLPP2, PLPPR2, PLPP1, SGPP2, INPP5K, PLPPR4, PLPP3, PLPPR1, PLPPR3, PLPP6, SGPP1 |
| lipid transfer activity | molecular function | TTPA, CPTP, GLTP, PLEKHA8 |
| lipid transporter activity | molecular function | APOE, APOB, APOL3, ABCA12, ABCA4, ABCA13, APOF, ABCA5, APOD, APOA1, NPC1, SLCO2A1, RFT1, ABCA7, ABCA10, ABCA3, ATP8B1, ABCA2, APOM, MTTP, ABCA6, GM2A |
| lipoamidase activity | molecular function | SIRT4 |
| lipoate synthase activity | molecular function | LIAS |
| lipoic acid binding | molecular function | INSR |
| lipopeptide binding | molecular function | CD1C, TLR1, CD1E, LBP, TLR6 |
| lipopolysaccharide binding | molecular function | TLR4, TLR2, HSPD1, DROSHA, ZRANB2, PSMA1, LY96, CAMP, PSMB4, SCARB1, RNASE2, DMBT1, HMGB1, SELP, BPIFC, BPIFA2, DEFB114, RNASE3, P2RX7, TREM2, ADGRB1, BPI, PTAFR, CD6, SPON2, F2, LBP, RNASE7 |
| lipopolysaccharide receptor activity | molecular function | TLR4, TLR2, LY96, SCARB1, PTAFR |
| lipoprotein lipase activator activity | molecular function | APOA5, APOH |
| lipoprotein lipase activity | molecular function | LPL, LIPG |
| lipoprotein particle binding | molecular function | APOE, LPL, GPIHBP1, APOA1, TREM2, CDH13, CD36 |
| lipoprotein particle receptor activity | molecular function | APOBR |
| lipoprotein particle receptor binding | molecular function | APOA5, LRP1, RELN |
| lipoteichoic acid binding | molecular function | DMBT1, TREM2, CD6, LBP |
| lipoteichoic acid immune receptor activity | molecular function | CD36 |
| lipoyl synthase activity (acting on glycine-cleavage complex H protein | molecular function | LIAS |
| lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein) | molecular function | LIAS |
| lithium ion binding | molecular function | PDXK, IMPA1 |
| lithium:proton antiporter activity | molecular function | SLC9B2 |
| lithocholic acid binding | molecular function | VDR |
| lithocholic acid receptor activity | molecular function | VDR |
| long-chain acyl-CoA hydrolase activity | molecular function | BAAT, ACOT11 |
| long-chain fatty acid binding | molecular function | FABP3, UCP1, RIDA, PRR7 |
| long-chain fatty acid transporter activity | molecular function | FABP5, SLC27A3, SLC27A5, FABP3, SLC27A1, MFSD2A, SLC27A2, SLC27A4, ABCD1, CD36 |
| long-chain fatty acid-CoA ligase activity | molecular function | ACSL3, ACSL1, ACSBG2, SLC27A3, SLC27A5, SLC27A1, ACSL5, ACSL4, SLC27A2, SLC27A4, ACSBG1 |
| long-chain fatty acyl-CoA binding | molecular function | SCP2, DBI, PNPLA3, ACOT7, ACOT11 |
| long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity | molecular function | HAO2, HAO1 |
| long-chain-3-hydroxyacyl-CoA dehydrogenase activity | molecular function | HADHA |
| long-chain-acyl-CoA dehydrogenase activity | molecular function | ACAD11, ACAD9, ACADVL, ACADL |
| long-chain-alcohol oxidase activity | molecular function | ALDH3A2 |
| long-chain-aldehyde dehydrogenase activity | molecular function | ALDH3A2 |
| long-chain-enoyl-CoA hydratase activity | molecular function | HSD17B4, HADHA |
| low voltage-gated calcium channel activity | molecular function | CACNA1G, CACNA1I, CACNA1H |
| low-affinity glucose:sodium symporter activity | molecular function | SLC5A2, SLC5A9 |
| low-affinity IgG receptor activity | molecular function | FCGR2B |
| low-affinity phosphate transmembrane transporter activity | molecular function | ADAMTS8 |
| low-affinity sodium:dicarboxylate symporter activity | molecular function | SLC13A2 |
| low-density lipoprotein particle binding | molecular function | CRP, LDLR, COLEC12, SCARB1, THBS1, LIPC, STAB1, SORL1, TREM2, CDH13, APCS, PCSK9, SCARF1, STAB2, CD36 |
| low-density lipoprotein particle receptor activity | molecular function | OLR1, CXCL16, LDLR, VLDLR, LRP6, STAB1, LRP12, SORL1, LRP1, LRP10, STAB2, CD36 |
| low-density lipoprotein particle receptor binding | molecular function | APOE, APOB, CRP, LANCL1, HSP90B1, SYT1, PICALM, DKK1, AP2M1, MESD, LRPAP1, CLTC, HSPG2, APOA5, ANKRA2, AP2A1, PCSK9, SNX17 |
| LRR domain binding | molecular function | LRRFIP2, KRAS, ZXDC, POLR2J, ROBO1 |
| luteinizing hormone receptor activity | molecular function | LHCGR |
| lutropin-choriogonadotropic hormone receptor binding | molecular function | ATP2A2 |
| lyase activity | molecular function | HSD17B4, OGG1, CYP17A1, ADCY2, ENO1, CBSL, CBS, APEX1, ADCY10, CA2, MLYCD, PAM, DERA, CSAD, GLDC, PTS, GLO1, NEIL1, HACL1, HACD1, HCCS, MGST3, FECH, PDXDC1, MGST2, PAICS, ECHS1, ECHDC2, PPCDC, AMD1, RPS3, TKFC, UROD, ILVBL, ENO2, ODC1, AUH, PCK2, ACO2, RNASE2, DDC, CA5A, CA9, CA13, NEIL2, MOCOS, NPL, FTCD, XRCC6, SDSL, GMDS, ALDOB, HAL, GUCY2F, NTHL1, HACD2, UXS1, APIP, GAD1, PTGES2, GGCT, ALDOA, HMGB1, GUCY1B1, CA14, GUCY1A2, HADHA, FASN, GUCY1A1, HACD3, GADL1, ADCY6, ADSL, ADCY8, TPI1, PHYKPL, L3HYPDH, ADCY7, PTGIS, DGLUCY, NAXD, SCLY, ECHDC1, FH, CTH, CA12, ALAD, ENOSF1, ADCY9, ENO3, GSTM4, LTC4S, ALOXE3, NPR1, HMGCL, KYAT1, GUCY2D, FAHD1, ADCY4, CA3, UMPS, CA7, THNSL2, POLB, ALDOC, UROS, ACO1, MVD, ALKBH1, TSEN2, NEIL3, CHAC1, ADCY5, SDS, HOGA1, UROC1, SRR, POLL, ALOX12B, ASL, NPR2, CYP2S1, PISD, CA4, URAD, TYW1B, CLYBL, TYW1, CA1, PCBD1, GAD2, HMGCLL1 |
| Lys48-specific deubiquitinase activity | molecular function | USP13, MINDY4, MINDY1, MINDY3, DESI2, ATXN3, USP27X, CYLD, MINDY2, YOD1, USP7, USP9X, USP15, OTUD5, OTUD7B |
| Lys63-specific deubiquitinase activity | molecular function | PSMD14, STAMBPL1, DESI2, ATXN3, USP27X, CYLD, YOD1, OTUD5, STAMBP, OTUD4 |
| lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | molecular function | EP300, NAT8, KAT2B |
| lysine N-methyltransferase activity | molecular function | SETD9, SMYD2, KMT5A |
| lysine-acetylated histone binding | molecular function | BRD2, BRDT, BRD4, TRIM24, CARM1, SMARCA4, BRD9, YEATS4, PHIP, MLLT3, TAF1, KMT2A, BAZ2A, ZMYND8, BRD3, DPF2, ATAD2B |
| lysine-tRNA ligase activity | molecular function | KARS1 |
| lysophosphatidic acid acyltransferase activity | molecular function | ABHD5, AGPAT3, PNPLA3, AGPAT4, ABHD4 |
| lysophosphatidic acid binding | molecular function | LPAR4, PPT1, PNPLA3, TPP1, LPAR1, VIL1, CLN6, GAP43 |
| lysophosphatidic acid phosphatase activity | molecular function | ACPP, ACP6 |
| lysophosphatidic acid receptor activity | molecular function | LPAR4, LPAR6, LPAR1, LPAR3, LPAR2 |
| lysophosphatidylcholine flippase activity | molecular function | MFSD2A |
| lysophospholipase activity | molecular function | PNPLA8, LYPLAL1, ENPP2, ABHD12B, PLA2G4C, GDPD3, ABHD12, LYPLA1, ABHD16A, LIPC, LGALS13, PLA2G4A, PNPLA6, PLA2G15, GDE1, PNPLA7, ASPG, ABHD4, MGLL, PLB1, GDPD1 |
| lysophospholipid acyltransferase activity | molecular function | LPCAT3, LPCAT4, MBOAT7 |
| lysophospholipid:sodium symporter activity | molecular function | MFSD2A |
| lysozyme activity | molecular function | LYZ, SPACA3, LYZL6, LYZL1, LYZL2 |
| m7G(5')pppN diphosphatase activity | molecular function | NUDT4, NUDT5, DCP2, NUDT1, NUDT16, DCPS, NUDT3 |
| macromolecular complex binding | molecular function | MTOR, PRNP, SKIL, ATP6V1B1, NASP, HNRNPU, SLF2, CAB39, NDUFA4, CEBPG, MAX, SCAP, MLC1, CIR1, TSG101, MTA3, PLK2, XRCC5, IQGAP1, CDK5RAP1, VPS28, TULP3, BCL10, RARB, EPCAM, CAPN2, ATF1, ATP5PF, UQCRC2, CPS1, PXN, ST13, PPP2R2A, PFKP, GRIN1, DDX39B, PPP1R9B, NUP58, RTN4R, FZD4, PRKAB1, CTSV, VPS4B, CRYAB, P4HB, PTPRF, CTNNA1, FBN1, NSF, NDUFA8, PDCL, DAB2IP, SCFD1, LZTFL1, SLC9A3R1, KRAS, RPS3, EPHB2, NUP62, GCLC, ERCC6, JDP2, DDB2, KCNN1, MCM9, DLGAP1, PRKN, TFRC, RRAS, GNB1, TSC1, VPS33B, GNB4, BAG3, IDE, SPTBN1, TAB1, PEX26, ING2, VIPAS39, DISC1, CEP131, SLC27A5, NCK2, DEPDC5, CCND1, ERCC5, FCGR2B, IST1, CTBP2, ERCC8, CHRNA2, UFD1, NACC2, PANX1, WRAP53, NOD2, HOMER2, TULP2, OPA1, ADRB2, ITGAM, XRCC6, PRMT2, RELA, SLC3A1, FADD, CHMP6, SUCLG2, GIT1, FBLN1, GUCY2F, PDX1, EPHB1, CAV3, GAD1, PSMG3, DCLRE1B, ULK1, ITGA2, SQSTM1, CEBPE, SKAP1, PINK1, POLDIP3, CFLAR, STRN, TUBB, PCSK2, GUCY1A2, HADHA, ATP5ME, BIRC2, IKBKG, WIZ, YWHAE, DET1, SHARPIN, CRIPT, CLTA, CDKN1B, BCAP31, GRB2, RAC1, AP2B1, SLC25A3, PPP3CA, ST |
| macrophage colony-stimulating factor receptor activity | molecular function | MST1R, CSF1R |
| macrophage colony-stimulating factor receptor binding | molecular function | CSF1, STAP1, IL34 |
| macrophage migration inhibitory factor binding | molecular function | COPS5, CD74 |
| MADS box domain binding | molecular function | NKX3-1 |
| magnesium ion binding | molecular function | TSSK4, TSSK6, WEE1, ADCY2, ENO1, PRPS2, PTEN, GNAI1, BRSK2, PDXK, IDH1, COMT, EPHX2, TOP2A, MAST2, ADCY10, MOV10L1, THG1L, MSH2, ALPP, PRPS1L1, IDI1, FAN1, ATP10B, MTHFD2, IMPA1, PAPOLA, STK3, ENOPH1, HACL1, DYRK3, ATP8B3, PPM1B, ALPI, FEN1, ATP8B4, DHX36, NUDT5, PGM3, ATP8B2, STK4, MARK2, NT5C3B, MTPAP, ATP10D, MAP3K7, ADSS2, SNCA, PPA2, MAP3K20, SUCLA2, PRKACB, GCLC, STK38, PGM1, ENDOV, SRPK1, ILVBL, ENO2, PKM, ARL3, MAP3K8, SRPK2, NT5C1A, DCTPP1, GEM, ARF1, TDG, LHPP, XYLT2, UBA2, OPA1, MAP3K6, PRPS1, SUCLG2, STK38L, IRAK3, DXO, TKT, MSH6, ADPRH, PSPH, DYRK2, SNRK, MAP2K7, GLUL, RPS6KA2, NUDT16, CIB3, PINK1, ATP9B, PLK1, PGM5, TSSK3, NUDT12, IDH3B, ATP9A, PDCD6, RAN, RHEB, ADSS1, MAST4, ERN1, DUT, IDH2, ITPK1, CERK, ATP8A2, NLK, ATP11B, CIB2, TDP2, ABL1, NCS1, NT5C1B, MAP3K5, STK26, PGP, LATS1, HPRT1, IDH3G, FOXK2, PRPSAP1, PPA1, GEN1, PI4K2A, FARSB, SIK3, S100P, PPM1A, ABL2, ATP11A, RPS6KA1, ENOSF1, TESC, PGM2, EXD2, ATP8A1, ENO3, MAPK12, PUDP, CILK1, ATP10A, HMGCL, IDH3A, SIK2, CDC42BPB, RPS6KA5, OXSR1, |
| magnesium ion transmembrane transporter activity | molecular function | CNNM2, MMGT1, NIPA2, ZDHHC17, SLC41A1, CLDN16, CNNM4, MAGT1, NIPAL3, ZDHHC13, NIPAL1, NIPAL4, NIPA1, NIPAL2 |
| magnesium-dependent protein serine/threonine phosphatase activity | molecular function | ILKAP, PPM1B, TAB1, PPM1L, PPM1K, PPM1J, PPM1G, PDP1, PP2D1, PPM1A, PDP2, PPM1E, PPM1H |
| magnesium:sodium antiporter activity | molecular function | SLC41A1 |
| malate dehydrogenase (decarboxylating) (NAD+) activity | molecular function | ME1, ME2, ME3 |
| malate dehydrogenase (decarboxylating) (NADP+) activity | molecular function | ME1, ME2, ME3 |
| malate dehydrogenase (NADP+) activity | molecular function | MDH2 |
| malate dehydrogenase activity | molecular function | LIPF, MDH2, MDH1, MDH1B |
| malate synthase activity | molecular function | CLYBL |
| malate transmembrane transporter activity | molecular function | SLC25A10 |
| maleylacetoacetate isomerase activity | molecular function | GSTZ1 |
| malic enzyme activity | molecular function | MDH1, ME1, ME2, ME3 |
| malonate-semialdehyde dehydrogenase (acetylating) activity | molecular function | ALDH6A1 |
| malonyl-CoA decarboxylase activity | molecular function | MLYCD |
| malonyl-CoA synthetase activity | molecular function | ACSF3 |
| maltose alpha-glucosidase activity | molecular function | GAA, MGAM, GANC |
| manganese ion binding | molecular function | SOD2, ADCY2, ADCY10, IDI1, IMPA1, PAPOLA, PPM1B, FEN1, GYG1, GALNT2, MTPAP, PPEF2, LARGE2, EXTL2, LAP3, DCP2, ME1, PCK2, ATP13A2, LARGE1, ATP2C1, XYLT2, MGAT5B, FAM20C, DYRK2, GLUL, MRE11, GALNT4, NUDT16, PPEF1, PEPD, XPNPEP1, TDP2, ABL1, B4GALT1, NEK4, GALNT1, MPPED2, XPNPEP3, PPM1A, ABL2, EXD2, ADPRM, HMGCL, POMGNT1, MGAT2, CDIPT, ABO, XXYLT1, NPEPL1, PRIMPOL |
| manganese ion transmembrane transporter activity | molecular function | TMEM165, SLC30A10, SLC39A8, SLC11A1, SLC39A14 |
| manganese transmembrane transporter activity, phosphorylative mechanism | molecular function | ATP2C1, ATP13A1, ATP2C2 |
| mannokinase activity | molecular function | HKDC1, HK2, GCK, HK3 |
| mannose binding | molecular function | ACR, IGF2R, CLEC6A, LMAN2L, LMAN1, LMAN2, MRC1, COLEC11, CD209, MANBA, CLEC4A, MBL2, LMAN1L |
| mannose-1-phosphate guanylyltransferase activity | molecular function | GMPPB |
| mannose-6-phosphate isomerase activity | molecular function | MPI |
| mannose-ethanolamine phosphotransferase activity | molecular function | PIGO, PIGN, PIGF, PIGG |
| mannosidase activity | molecular function | MAN2B1, MAN2A1, MAN2A2, MAN1A1 |
| mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity | molecular function | ENGASE |
| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | molecular function | MAN1B1, EDEM2, EDEM3, MAN1A2, EDEM1, MAN1C1, MAN1A1 |
| mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity | molecular function | MAN2A1, MAN2A2 |
| mannosyltransferase activity | molecular function | DPY19L2, TMTC2, DPY19L1, PIGM, PIGV, TMTC1, PIGB, DPY19L3, DPY19L4, TMTC4, ALG1, POMT1, ALG3 |
| MAP kinase activity | molecular function | MAPK3, MAPK1, MAPK8, MAPK14, MOK, MAPK6, MAPK11, MAPK4, SRPK1, SRPK2, MAPK9, NLK, MAPK7, MAPK12, CILK1, SRPK3, MAPK15, MAPK13, MAPK10 |
| MAP kinase kinase activity | molecular function | MAPK14, MAPKAPK5, MAP2K4, MAP2K3, MAP2K7, MAP2K2, MAP3K9, MAP2K6, MAPKAPK3, MAP2K1, PAK3, MAP2K5, MAPK10, LRRK2 |
| MAP kinase kinase kinase activity | molecular function | EGFR, RAF1, MAP3K4, MAP3K7, MAP3K20, MAP3K8, TAOK2, MAP3K15, MAP3K6, TAOK3, MAP3K3, MAP3K13, MAP3K12, MAP3K9, MAP3K5, TAOK1, MAP3K2, MAP3K10, MAP3K14, MOS, MAP3K1 |
| MAP kinase kinase kinase kinase activity | molecular function | MAP4K2, MAP4K1, MAP4K3 |
| MAP kinase phosphatase activity | molecular function | DUSP3, DUSP10 |
| MAP kinase serine/threonine phosphatase activity | molecular function | PP2D1 |
| MAP kinase tyrosine phosphatase activity | molecular function | DUSP8, DUSP5, DUSP1, DUSP16, DUSP2, DUSP10 |
| MAP kinase tyrosine/serine/threonine phosphatase activity | molecular function | DUSP6, DUSP8, DUSP21, DUSP14, DUSP5, DUSP18, DUSP1, DUSP7, DUSP9, DUSP16, DUSP2, DUSP10 |
| MAP-kinase scaffold activity | molecular function | IQGAP1, DUSP19, MAPK8IP1, SH3RF1, MAP2K2, KSR1, AKAP13, MAP2K1, MAPK8IP2 |
| mast cell secretagogue receptor activity | molecular function | MRGPRX2 |
| MDM2/MDM4 family protein binding | molecular function | CDKN2A, MARCHF7, CDK5RAP3, RFWD3, PPARA, TP53 |
| mechanically-gated potassium channel activity | molecular function | KCNK4 |
| mechanosensitive ion channel activity | molecular function | TMC5, TMEM63A, TMC7, PIEZO2, TMC4, TMC6, TMC1, TMEM63B, TMC8, TMC3, PIEZO1, TMC2 |
| mediator complex binding | molecular function | GLI3, SMC3, NIPBL, SMC1A |
| medium-chain acyl-CoA hydrolase activity | molecular function | BAAT |
| medium-chain fatty acid-CoA ligase activity | molecular function | ACSF2 |
| medium-chain-(S)-2-hydroxy-acid oxidase activity | molecular function | HAO2, HAO1 |
| medium-chain-acyl-CoA dehydrogenase activity | molecular function | ACADM, ACAD11, ACAD9 |
| medium-chain-aldehyde dehydrogenase activity | molecular function | ALDH3A2 |
| melanin-concentrating hormone activity | molecular function | PMCH |
| melanin-concentrating hormone receptor activity | molecular function | MCHR1 |
| melanocortin receptor activity | molecular function | MC2R, MC1R, MC3R |
| melanocortin receptor binding | molecular function | ASIP |
| melanocyte-stimulating hormone receptor activity | molecular function | MC1R, MC3R |
| melatonin binding | molecular function | NQO2 |
| melatonin receptor activity | molecular function | MTNR1A |
| membrane curvature sensor activity | molecular function | ICA1 |
| membrane insertase activity | molecular function | COX18, OXA1L |
| mercury ion binding | molecular function | PARK7, FN1 |
| metal chelating activity | molecular function | APOE |
| metal ion binding | molecular function | NR5A2, SOD1, TIMP1, ESR1, TP53, CYP1A1, PGR, MMP2, AR, VDR, CYP19A1, ACE, MMP9, RAG1, WT1, PTGS1, NOS3, PTGS2, BRCA1, LIG4, TNFSF10, GNAS, PLOD1, CYP24A1, NR5A1, BAK1, AMHR2, TSSK4, ESR2, TSSK6, DNMT3L, TERT, BIRC5, ZEB2, NR1I2, BGLAP, SOD2, CYP17A1, CYP1A2, SP1, HMOX1, MGMT, ERCC2, CYP2B6, XPA, DNMT1, PON1, WEE1, S100A12, MDM2, ADCY2, GAS6, UBR2, CTCFL, MTR, CIB1, RNF17, PEG3, DNMT3B, MBD1, PLAGL1, DMRT1, MTA2, CRP, ALB, TF, NR3C1, APP, CYP11A1, ITGB1, ENO1, ITGA5, GNAO1, PARP1, CBSL, PRPS2, F5, CYP11B1, PRLR, ACAT1, CBS, GNAI1, CSNK2B, TNP2, CLCA4, PON2, BRSK2, ADAMTS1, MAN1B1, ADAMTS5, SPO11, DMRT2, ZFP37, KAT7, GH1, LTF, CAT, SEMG1, AMY2A, ITGAV, KIT, ITGA4, LPO, ITGA6, NOS2, MMP12, XDH, CACNA2D1, NANOS2, CYCS, BMPR2, LIN28B, APOA1BP, EBF2, ZDBF2, CDC7, PDXK, MEFV, IDH1, CABYR, RAF1, CYP21A2, MMP7, THRB, CDH1, ARSA, CYP11B2, COMT, CALB2, NR2F2, APEX1, EPHX2, PPARG, GATA4, ADAMTS20, SEMG2, CDH18, SHH, CYP1B1, NANOS1, CLEC7A, ZNF331, CYP26B1, PICK1, DROSHA, DICER1, RNF114, PEX10, RNF8, CYB5A, MT-CO1, TOP2A, |
| metal ion transmembrane transporter activity | molecular function | SLC12A2, TMEM165, SLC39A9, SLC39A12, SLC39A10, SLC39A5, SLC39A11, SLC39A8, SLC39A6, SLC39A13, SLC11A1, SLC39A3, SLC39A4, SLC39A1, SLC39A14, SLC39A7 |
| metal ion:proton antiporter activity | molecular function | SLC11A1 |
| metalloaminopeptidase activity | molecular function | LTA4H, ERAP1, METAP2, ERAP2, AOPEP, NPEPPS, MMP15, XPNPEP2, MMP16, METAP1D, MMP14, XPNPEP1, DNPEP, XPNPEP3, LNPEP, LVRN, ENPEP, RNPEPL1, TRHDE, ANPEP, MMP17, METAP1 |
| metallocarboxypeptidase activity | molecular function | CPN1, ACE2, AGBL2, AGBL4, CPM, CPZ, CPXM2, FOLH1B, CPXM1, VASH2, CPA3, CPA5, AGBL5, CPD, PEPD, FOLH1, CPE, AEBP1, CPA6, CPA1, VASH1, CPA2, AGBL1 |
| metallochaperone activity | molecular function | ATOX1 |
| metallodipeptidase activity | molecular function | ACE, CPQ, DPEP1 |
| metalloendopeptidase activity | molecular function | MMP2, MMP9, CLCA4, ADAMTS1, ADAMTS5, MMP12, MMP7, ADAMTS20, PMPCB, ADAM32, COPS5, ATP23, UQCRC2, ZMPSTE24, ECE2, EEF1AKMT4-ECE2, ECE1, OMA1, ADAM29, ADAM11, MMEL1, IDE, ADAMTS9, TLL2, MMP15, ADAMTS18, MMP28, MMP23B, THOP1, PHEX, PMPCA, BMP1, MMP16, ADAM18, YBEY, YME1L1, NLN, AFG3L2, MMP14, ADAM2, MBTPS2, NRDC, ADAM9, ADAM22, TRABD2B, ADAMDEC1, MMP20, ADAMTS19, ADAM30, TLL1, ADAMTS2, MIPEP, MMP25, ADAM23, ADAMTS10, ECEL1, MMP13, MMP21, ADAMTS14, RCE1, MME, KEL, ADAMTS17, MMP10, LMLN, MMP19, ADAMTS15, ADAM19, ADAMTS6, SPG7, MMP11, ADAM8, ADAMTS13, TRABD2A, ADAMTS7, ADAMTS8, ASTL, MMP17, ADAMTS4, ADAMTS3, ADAM12, ADAMTS12, PITRM1, ADAM33, MMP8 |
| metalloendopeptidase inhibitor activity | molecular function | TIMP1, NGF, TIMP2, BST2, TIMP3, SPOCK2, RARRES1, COL4A3, SPOCK1, WFIKKN2, TIMP4, WFIKKN1, LXN, RECK, FETUB |
| metalloexopeptidase activity | molecular function | ERAP1, METAP2, ZMPSTE24, DPEP3, LAP3, RNPEP, NUDT16, METAP1D, DPEP2, DPEP1, NPEPL1, METAP1 |
| metallopeptidase activity | molecular function | MMP2, ACE, MMP9, CLCA4, ADAMTS1, ADAMTS5, MMP12, MMP7, ADAMTS20, CPN1, ACE2, EIF3H, PMPCB, LTA4H, AGBL2, AGBL4, ADAM32, COPS5, ERAP1, CPM, ERAP2, ERMP1, AOPEP, ATP23, PSMD14, CPZ, FOLH1B, CPQ, ZMPSTE24, ECE2, EEF1AKMT4-ECE2, ECE1, OMA1, STAMBPL1, DPEP3, DPP3, ADAM29, ADAM11, NPEPPS, AMZ2, RNPEP, MMEL1, IDE, CPXM1, ADAMTS9, TLL2, MMP15, ADAMTS18, MMP28, CHMP1A, NAALADL1, NAALAD2, MMP23B, THOP1, PAPPA2, XPNPEP2, PHEX, CNDP1, CNDP2, BMP1, CPA3, CPA5, MMP16, AGBL5, ADAM18, CPD, PEPD, YME1L1, NLN, AFG3L2, MMP14, MYSM1, ADAM2, XPNPEP1, DNPEP, MBTPS2, NRDC, ADAM9, ADAM22, TRABD2B, ADAMDEC1, MMP20, FOLH1, ADAMTS19, XPNPEP3, ADAM30, TLL1, ADAMTS2, MIPEP, MMP25, LNPEP, ADAM23, ADAMTS10, ECEL1, MMP13, LVRN, MMP21, ADAMTS14, STAMBP, MME, CPE, KEL, ADAMTS17, DPEP2, MMP10, ENPEP, CPA6, LMLN, MMP19, RNPEPL1, ADAMTS15, ADAM19, ADAMTS6, TRHDE, SPG7, CPA1, MMP11, ADAM8, ADAMTS13, TRABD2A, ADAMTS7, ADAMTS8, ANPEP, AMZ1, ASTL, MMP17, ADAMTS4, CPA2, MPND, AGBL1, ADAMTS3, ADAM12, DPEP1, ADAMTS12, PITRM1, ADAM33, MMP8 |
| methanethiol oxidase activity | molecular function | SELENBP1 |
| methenyltetrahydrofolate cyclohydrolase activity | molecular function | MTHFD1, MTHFD2, MTHFD2L |
| methionine adenosyltransferase activity | molecular function | MAT2A, MAT1A |
| methionine adenosyltransferase regulator activity | molecular function | MAT2B |
| methionine synthase activity | molecular function | MTR |
| methionine-R-sulfoxide reductase activity | molecular function | MSRB1 |
| methionine-tRNA ligase activity | molecular function | MARS1 |
| methionyl-tRNA formyltransferase activity | molecular function | MTFMT |
| methotrexate binding | molecular function | DHFR, FOLR1 |
| methotrexate transporter activity | molecular function | SLC19A1 |
| methyl indole-3-acetate esterase activity | molecular function | CES1, CES2 |
| methyl-CpG binding | molecular function | DNMT1, MBD3L1, MBD2, MBD1, LRWD1, WDR77, ZBTB4, CXXC5, MECP2, CHTOP, TET3, ZBTB38, TET1, UHRF1, ZBTB33, PRMT1, ZBTB21, MBD3, ERH, HOXB13, CDX2, CDX1, LHX4 |
| methyl-CpNpG binding | molecular function | ZBTB4 |
| methylarsonate reductase activity | molecular function | GSTO1, GSTO2 |
| methylarsonite methyltransferase activity | molecular function | N6AMT1 |
| methylated histone binding | molecular function | FMR1, LRWD1, CDY1, CBX2, TRIM24, PHF1, MBTD1, CXXC1, ING1, ATRX, RBBP5, TDRD3, KDM4A, NCAPD3, SUZ12, PHF2, WDR5, GLYR1, MSL3, ING2, L3MBTL1, CBX8, FAM156A, MSH6, ING3, PHF8, BPTF, ZMYND11, UHRF1, PYGO1, TP53BP1, KMT2E, CDYL2, SGF29, MTF2, L3MBTL2, SPIN2A, ZMYND8, KDM5A, CBX5, KDM8, CHD8, CBX4, ING5, NCAPG2, ING4, RAG2 |
| methylated-DNA-[protein]-cysteine S-methyltransferase activity | molecular function | MGMT |
| methylcytosine dioxygenase activity | molecular function | TET3, TET1, ALKBH1, TET2 |
| methylenetetrahydrofolate dehydrogenase (NAD+) activity | molecular function | MTHFD1, MTHFD2, MTHFD2L |
| methylenetetrahydrofolate dehydrogenase (NADP+) activity | molecular function | MTHFD1, MTHFD2, MTHFD1L, MTHFD2L |
| methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity | molecular function | MTHFD1 |
| methylenetetrahydrofolate reductase (NAD(P)H) activity | molecular function | MTHFR |
| methylglutaconyl-CoA hydratase activity | molecular function | AUH |
| methylglyoxal synthase activity | molecular function | TPI1 |
| methylmalonate-semialdehyde dehydrogenase (acylating) activity | molecular function | ALDH6A1 |
| methylmalonyl-CoA epimerase activity | molecular function | MCEE |
| methylputrescine oxidase activity | molecular function | AOC1 |
| methylthioribulose 1-phosphate dehydratase activity | molecular function | APIP |
| methylthiotransferase activity | molecular function | CDK5RAP1, CDKAL1 |
| methyltransferase activity | molecular function | MGMT, DNMT1, EZH2, MTR, DNMT3B, NSUN7, COMT, PRMT6, PRDM9, PCMT1, GAMT, SETD3, METTL25, TYMS, TRMT2A, METTL2A, PRDM13, METTL7A, NSUN2, METTL2B, CARM1, NSD1, NSD3, TFB2M, SETD4, GNMT, NDUFAF5, METTL21C, CIAPIN1, EEF1AKMT1, SETDB2, DIMT1, ECE2, EEF1AKMT4-ECE2, NSUN6, COQ3, PRDM2, KMT5B, NDUFAF7, METTL21A, TRMT5, HENMT1, TYW3, SETD9, EHMT2, METTL18, ATPSCKMT, SETD6, TRMT61A, TRMT13, PEMT, NSUN5, PRDM8, KMT2D, RNMT, PRDM1, PRMT2, TRMT10C, METTL5, METTL15, FTSJ1, TRMT44, CMTR2, FAM86B1, METTL6, THUMPD2, BHMT2, NSUN3, EHMT1, PRMT8, TRMT9B, TPMT, COQ5, DOT1L, NSD2, KMT2A, MEPCE, KMT2C, EEF2KMT, ANTKMT, SETD5, LCMT1, SETD1B, FBL, EMG1, TGS1, THUMPD3, NTMT1, ARMT1, BUD23, CARNMT1, SETD7, EEF1AKMT3, METTL22, TRMT61B, PRDM6, SETDB1, BMT2, TRMT1L, DPH5, VCPKMT, PRDM4, HNMT, METTL23, TFB1M, LRTOMT, SUV39H2, ASH1L, TRDMT1, ETFBKMT, PRMT1, PRDM12, NOP2, KMT5C, TRMT10A, METTL17, MECOM, SPOUT1, SMYD5, METTL27, PRDM5, CAMKMT, CMTR1, ALKBH8, MRM3, PRDM10, FAM86C1, LCMT2, TRMT1, HEMK1, FTSJ3, PRDM16, PRDM7, EEF1AKNMT, SMYD1, SET |
| methylumbelliferyl-acetate deacetylase activity | molecular function | CES1, ESD, CES2 |
| mevalonate kinase activity | molecular function | MVK |
| mevalonate transmembrane transporter activity | molecular function | SLC16A1 |
| MH1 domain binding | molecular function | HMGA2 |
| MH2 domain binding | molecular function | HMGA2 |
| MHC class I protein binding | molecular function | HLA-E, CD8A, ATP5F1B, DERL1, TAP1, TAP2, PILRB, TUBB, TUBB4B, TAPBP, BCAP31, CD244, CD8B |
| MHC class I protein complex binding | molecular function | KLRC1, KLRC2, TAPBPL, CD160 |
| MHC class I receptor activity | molecular function | MR1, CD160, KLRF1 |
| MHC class Ib protein binding | molecular function | TAP1, KIR2DS4, TAP2, KIR3DL2 |
| MHC class Ib receptor activity | molecular function | CD160 |
| MHC class II protein binding | molecular function | CD74, CD81, COL2A1, CD4 |
| MHC class II protein binding, via antigen binding groove | molecular function | CD74 |
| MHC class II protein complex binding | molecular function | HLA-DRB1, HSP90AA1, HLA-DRA, HSPA8, CD74, CD81, PKM, HLA-DMB, HLA-DOA, ANXA11, YWHAE, MS4A1, ATP1B1 |
| MHC class II receptor activity | molecular function | HLA-DRB1, HLA-DQB1, HLA-DRA, HLA-DQA1, HLA-DQA2, HLA-DOA, HLA-DPA1 |
| MHC protein binding | molecular function | CLEC7A, TAP1, TAP2, MARCHF1, MARCHF8 |
| microfibril binding | molecular function | LTBP2, LTBP1, ADAMTSL2 |
| microfilament motor activity | molecular function | MYH7, MYH10, MYH14, MYO5C, MYO5A, MYO6, MYO1B, MYO5B, MYO1F, MYO3A, MYO1C, MYH9, MYH3, MYH6, MYO7A, MYO9B, MYO7B, MYO1G, MYH8, MYO1D, MYH13, MYH2 |
| microtubule binding | molecular function | FMR1, BIRC5, OGG1, GAPDH, EZR, NME8, KIF3B, KIF26B, MAST2, KIF6, KATNB1, STARD9, KIF3A, S100A9, PRNP, KIF5B, VPS41, CENPE, ABRAXAS2, CAMSAP1, CEP57, KIF17, KIF2A, KIF20A, CETN2, FNTA, RAB11A, DPYSL2, NUSAP1, FHDC1, MAP1LC3A, DRG1, KIF1C, CAMSAP2, TRAF3IP1, SBDS, TOGARAM1, CCDC88B, KIF19, KIF24, CEP350, REEP1, KIF15, BCL2L11, KATNA1, VAPB, CRYAB, NEFH, CCDC181, MAPRE3, DYNC1I1, RPS3, CETN1, KIF14, CNN3, TPGS1, CDK5RAP2, FAM83D, MACF1, ZNF207, MAP4, KIF12, ARL3, CCDC88A, HOOK3, WDR90, MAP6D1, CCDC66, PRC1, RP1, MACO1, NEIL2, C10orf90, KIFC1, RCC2, DNM3, SNPH, OPA1, KIF1B, MAP4K4, FTCD, ABRAXAS1, VASH2, HOOK2, KIF16B, MX1, CENPF, RAE1, DST, CCDC170, CEP57L1, VAPA, DCX, PLK1, KIF5A, SAXO1, KIF2B, JAKMIP2, REEP4, CETN3, MAP2, APC, LRPPRC, TIAM1, MAP9, KIF20B, GAS2L1, DPYSL5, CRIPT, CLIP1, MAP1S, ALMS1, KRIT1, NUMA1, FAM161A, KIF18A, SKA2, ARHGEF2, KIFC3, CEP295, GABARAPL1, CCDC88C, MTUS1, CCDC187, PEX14, GABARAP, JAKMIP3, GAS2L3, MDM1, MAP6, CHP1, S100A8, GABARAPL2, CKAP5, KIF27, SVBP, MAP1LC3B, KIF9, HDGFL3, DCDC |
| microtubule lateral binding | molecular function | KIF5B |
| microtubule minus-end binding | molecular function | CAMSAP1, TUBGCP4, CAMSAP2, HAUS4, MACF1, TUBGCP3, NUMA1, CEP290, TUBGCP5, TUBGCP2, TUBGCP6, CAMSAP3 |
| microtubule motor activity | molecular function | DNAH9, KIF3B, KIF26B, KIF6, DNAH12, DYNC2H1, KLC4, DNAH1, STARD9, KIF3A, DYNC1H1, DNAH5, DNAH11, KIF5B, CENPE, DNAH6, DYNLRB1, DNAH2, KIF17, DNAH17, KIF2A, KIF20A, KIF1C, DYNLRB2, KIF19, KIF24, KLC2, KIF15, SMC3, DYNC1I1, KLC1, DYNC1I2, KIF14, KIF12, KIFC1, DYNC1LI2, KIF1B, KIF16B, BBS4, DNAH3, KIF5A, KIF2B, APPBP2, DNHD1, DNAI2, KIF20B, DNAL4, DYNC1LI1, DNAH10, KIF18A, DNAH8, KIFC3, KIF27, KIF9, KIF4A, KIF3C, KIF1A, KIF23, KLC3, KIF13B, KIF21B, KIF7, KIF18B, KIF25, KIF26A, KIF4B, DNAH14, KIF11, KIF22, KIF13A |
| microtubule plus end polymerase | molecular function | CKAP5 |
| microtubule plus-end binding | molecular function | MAPRE3, DST, TTBK2, APC, CLIP1, CLIP4, NUMA1, KIF18A, KNSTRN, TBCB, MAPRE1, CLASP2, CLASP1, CLIP2, STIM1, CLIP3 |
| microtubule-severing ATPase activity | molecular function | KATNB1, KATNA1, FIGNL1, KATNAL2, SPAST |
| mineralocorticoid receptor binding | molecular function | SMAD3 |
| minus-end directed microfilament motor activity | molecular function | MYO6 |
| miRNA binding | molecular function | FMR1, SOX2, MATR3, PUM1, HNRNPA1, ZC3H12A, ZC3H7A, AGO4, RBM10, HNRNPA2B1, DDX21, YBX1, TARBP2, AGO3, ZC3H10, RC3H1, PNPT1, RBM4, AGO2, SOX4, TRIM71, ZC3H7B, AGO1, SPOUT1, TUT4, TUT7, ZNF346, LIN28A |
| misfolded protein binding | molecular function | CLU, BAG6, HSPA5, HSPA8, DERL2, DNAJC10, HSPA14, DERL1, DNAJB9, SDF2L1, STUB1, F12, HSPA13, RHBDD2, DNAJC3, HDAC6, CLUL1, EDEM1, HSPA6, DERL3, HSPA1A, HSPA1B |
| mismatched DNA binding | molecular function | MSH4, MSH5, MLH1, PMS2, MLH3, MSH2, PMS1, APTX, TDG, MSH6 |
| MIT domain binding | molecular function | IST1, CAPN7 |
| mitochondrial ATP-gated potassium channel activity | molecular function | CCDC51 |
| mitochondrial promoter sequence-specific DNA binding | molecular function | POLRMT, TFAM, LONP1 |
| mitochondrial proton-transporting ATP synthase complex binding | molecular function | ATP5IF1 |
| mitochondrial ribosome binding | molecular function | C1QBP, TACO1, MRPS27, OXA1L |
| mitochondrial sequence-specific DNA-binding transcription factor activity | molecular function | TFB2M, FOXO3 |
| mitochondrion targeting sequence binding | molecular function | TOMM20, TOMM20L |
| mitogen-activated protein kinase binding | molecular function | ACE, PTPRJ, NBR1, IQGAP1, DUSP8, MAPKAPK5, CDK5RAP3, ATF7, DUSP5, ABL1, MAPK7, TPR, GCH1, MICALCL, DUSP1, TNIP1, MAPKAPK3, DIRAS1, PTAFR, DUSP16, ARRB2, DUSP2, DUSP10 |
| mitogen-activated protein kinase kinase binding | molecular function | ACE, RAF1, TRIB3, PIN1, MAPK8IP1, DAB2IP, TAOK2, TRIB1, DLG1, KSR1, TRIB2 |
| mitogen-activated protein kinase kinase kinase binding | molecular function | MAPK1, CDC42, MAP4K2, DUSP19, MARVELD3, MAPK8IP1, PPEF2, DAB2IP, STK38, MAP2K4, DAZAP2, TRAF6, SASH1, TGFBR2, ROR2, TRAF2 |
| mitogen-activated protein kinase p38 binding | molecular function | NFATC1, TAB1, PRMT1, DUSP10 |
| Mo-molybdopterin cofactor sulfurase activity | molecular function | MOCOS |
| modification-dependent protein binding | molecular function | YEATS4, MLLT3, YEATS2 |
| modified amino acid binding | molecular function | MTHFR, CBS, CPS1, DPEP1 |
| molecular function regulator | molecular function | SMAD4 |
| molecular_function | molecular function | GNAS, NDRG2, DLK1, BRWD1, MSMB, DMRT2, TSPY1, EDDM3B, TAF7L, AIF1, SPAG11B, BSCL2, TEKT3, SLC6A8, SPATA25, DENR, PLCH2, ARL6IP5, VPS41, LRBA, REEP5, CFAP70, LHFPL2, H2AZ2, LRRC6, ZNF655, UBR7, TMEM116, PMFBP1, M1AP, TIMM21, C6orf62, MRPL47, HAUS2, ORC5, MFSD11, G0S2, TMEM50B, QRICH1, C3orf38, TTC27, GPR155, CCDC65, FAM184A, SCFD2, PHF3, TMEM106C, GHITM, C11orf1, CISH, ASNSD1, EMC3, TNN, OSGIN2, MPC1, FITM1, DISP2, CRYBA4, ATP5MPL, CSRP2, IFI44L, CWF19L1, DLEU7, CPNE8, TMEM126B, C19orf18, MDGA1, DCUN1D4, RAB5IF, TM6SF1, NYX, MRPL46, SMCO4, ZFAND5, PTTG1IP, KRT24, NDUFAF5, FNDC5, HAUS4, TMEM167B, NPAP1, STOX2, CDV3, CCPG1, SPCS1, TSPAN3, NXPH3, TPM3, TMSB15B, ZNF77, GRIPAP1, DHRS7B, WDR73, POMZP3, KRT73, TEX2, LRRC34, TRIM58, KIAA1191, H2AC12, AMDHD1, GGTLC1, C21orf62, DIP2B, NEMP1, ZNF324, SFT2D2, RWDD2B, C19orf57, MLLT11, GGTLC2, MIDN, TPRG1L, MBLAC2, ADNP2, SLC22A15, IMMP1L, C12orf57, TMEM126A, POPDC3, FANCF, NDRG4, SMIM24, HAUS5, TIAF1, TCTA, H2BC5, FHL1, ATRAID, OXR1, TC2N, ZNF114, KIF12, C1QTNF3, TMEM120A |
| molybdenum cofactor sulfurtransferase activity | molecular function | MOCOS |
| molybdenum ion binding | molecular function | SUOX, MOCOS, MTARC2, MTARC1 |
| molybdopterin adenylyltransferase activity | molecular function | GPHN |
| molybdopterin cofactor binding | molecular function | XDH, SUOX, MTARC2, GPHN, AOX1, MTARC1 |
| molybdopterin molybdotransferase activity | molecular function | GPHN |
| molybdopterin synthase activity | molecular function | MOCS2 |
| molybdopterin-synthase adenylyltransferase activity | molecular function | MOCS3 |
| molybdopterin-synthase sulfurtransferase activity | molecular function | MOCS3 |
| mono-ADP-D-ribose binding | molecular function | TRPM2 |
| mono-olein transacylation activity | molecular function | PNPLA3 |
| monoamine oxidase activity | molecular function | RNLS |
| monoamine transmembrane transporter activity | molecular function | SLC22A2, SLC6A2, SLC6A4, SLC18A2, SLC6A3, SLC22A1, SLC22A3 |
| monocarboxylate:sodium symporter activity | molecular function | SLC5A8 |
| monocarboxylic acid transmembrane transporter activity | molecular function | SLC16A7, SLC5A8, SLC16A5, SLC16A14, SLC16A10, SLC16A9, SLC16A13, SLC16A8, SLC16A1, SLC16A6, SLC16A12, SLC16A11 |
| monooxygenase activity | molecular function | CYP1A1, CYP19A1, CYP24A1, CYP17A1, CYP1A2, CYP2B6, CYP11A1, CYP11B1, CYP21A2, CYP11B2, CYP1B1, CYP26B1, PAM, DOHH, PAH, CYP2J2, CYP4A11, CYP4F3, CYP20A1, CYP2R1, CYP2A7, CYP2C8, CYP4F8, CYP26A1, CH25H, CYP4B1, CYP2A6, TYR, FMO3, CYP2C19, CYP4F22, MICAL3, CYP8B1, TPH1, CYP27B1, PTGIS, CYP3A5, TPH2, CYP2C18, CYP4F12, CYP51A1, MOXD1, TH, FMO4, MICAL2, CYP2E1, TBXAS1, CYP4F2, CYP4Z1, CYP4X1, CYP26C1, MICAL1, CYP46A1, DBH, CYP2D6, CYP2S1, CYP2D7, CYP2W1, TYRP1, FMO1, COQ7, CYP4F11, COQ6, CYP2C9, CYP3A43 |
| monophenol monooxygenase activity | molecular function | TYR, TYRP1 |
| monosaccharide binding | molecular function | PFKM, PFKP, ALPK1, FUOM, FBP1, TALDO1, RPIA, GPI, GNPNAT1, PFKL |
| monosialoganglioside sialyltransferase activity | molecular function | ST3GAL4, ST3GAL2 |
| monovalent cation:proton antiporter activity | molecular function | SLC9B2 |
| monovalent inorganic cation transmembrane transporter activity | molecular function | ASIC1 |
| morphogen activity | molecular function | NODAL, SHH, CER1, DAND5, NBL1, GREM1 |
| motilin receptor binding | molecular function | MLN |
| motor activity | molecular function | MYH7, DNAH9, DYNLT1, DNAH12, DYNC2H1, MYO19, DNAH1, MYO15A, DYNLL1, DYNC1H1, DNAH5, DNAH11, DNAI1, DNAH6, DYNLRB1, DNAH2, DNAH17, KIF2A, MYH10, KIF1C, MYL6, DYNLRB2, PIN1, MYH14, KIF15, TCTE3, DYNC2LI1, MYO5C, DYNC1I1, DYNLT3, KLC1, DYNC1I2, MYH7B, DNALI1, MYH11, MYO3B, MYO5A, DYNC1LI2, MYH1, CGNL1, DNAL1, DNAH3, GPR88, MYO6, MYO9A, KIF5A, DNAI2, DNAL4, DYNC1LI1, MYO1B, DNAH10, DNAH8, DCTN2, MYO5B, MYO10, MYO1F, MYO3A, MYO16, MYL6B, CCDC102A, KIF3C, KIF1A, MYO18B, MYO1C, MYH9, CGN, DYNLL2, MYH3, MYH6, MYO7A, MYO9B, MYO7B, KIF18B, MYO1G, MYH8, MYO15B, MYO1D, DNAH14, MYH13, MYH2 |
| MRF binding | molecular function | TSC22D3, CREBBP, BHLHE40, KLF5, BHLHE41 |
| mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity | molecular function | PCIF1 |
| mRNA (adenine-N1-)-methyltransferase activity | molecular function | TRMT61A, TRMT10C, TRMT61B |
| mRNA (cytidine-5-)-methyltransferase activity | molecular function | NSUN2 |
| mRNA (guanine-N7-)-methyltransferase activity | molecular function | RNMT, RAMAC |
| mRNA (N6-adenosine)-methyltransferase activity | molecular function | METTL16 |
| mRNA (nucleoside-2'-O-)-methyltransferase activity | molecular function | CMTR2, CMTR1 |
| mRNA 3'-UTR AU-rich region binding | molecular function | HNRNPA0, NUDT21, ZC3H12A, MEX3D, DHX36, EXOSC9, HNRNPD, TIA1, ILF3, ELAVL3, TIAL1, RBMS3, CPEB1, ELAVL4, ZFP36L2, EXOSC8, CPEB2, CPEB3, EXOSC4, ZFP36, ZFP36L1, RBM24, CPSF1, KHSRP, APOBEC1 |
| mRNA 3'-UTR binding | molecular function | FMR1, DAZL, PUM2, FUS, RPL5, CCT5, PCBP4, RPS7, HNRNPU, RNF20, TUT1, YBX3, PUM1, IGF2BP2, HNRNPR, FXR1, ZC3H12A, ZNF385A, DHX36, PARN, HNRNPC, RPL41, HNRNPA2B1, SERBP1, ELAVL2, AUH, ANGEL2, CPEB4, GEMIN5, UTP23, RBMS3, TAF15, CPEB1, FXR2, ELAVL4, RC3H1, CRYZ, CPEB2, SECISBP2L, RBM4, CARHSP1, RNF40, LARP1, CPEB3, PABPC5, RBM24, CSDC2, IGF2BP3, SECISBP2, PABPC4, RBM38, RSL1D1, IGF2BP1, NOVA1, TP53 |
| mRNA 5'-UTR binding | molecular function | FMR1, RPL5, CCT5, RPS3A, RPS7, RPS14, DDX3X, SHMT1, MYH10, MRPS11, IGF2BP2, RPS13, DHX36, RPL41, SYNCRIP, GNL3, UTP23, LARP6, LARP1, NCL, IGF2BP3, RPL26, RSL1D1, IGF2BP1, RARA |
| mRNA binding | molecular function | FMR1, HSP90AA1, MBD2, PIWIL2, PIWIL1, PARK7, NANOS2, C1QBP, RBMY1A1, RBMX, RBFOX2, DENR, ZC3H11A, CSTF2, MATR3, PCBP4, HNRNPA0, TDRD7, ZCCHC13, DDX3X, LSM1, NUDT21, TYMS, SNRNP70, HNRNPM, NCBP2, EIF4G2, ADARB1, G3BP1, PUM1, C12orf50, YTHDF1, NOVA2, IGF2BP2, RBM47, HNRNPR, SF3B1, HNRNPA1, RPL7, EIF2S2, FXR1, HNRNPA3, RPS13, GRSF1, ZC3H12A, CELF5, YTHDC1, RBM15, A1CF, RBM25, HNRNPD, SNRNP35, YTHDF3, RBM45, SRBD1, LSM14A, SNIP1, SRRM2, LUC7L2, SYNCRIP, PCF11, SSB, RPS2, RPS5, ESRP1, HNRNPA2B1, RPS3, RPL13A, RPL35, PCBP3, HDLBP, EIF3A, PCBP1, DHFR2, RBM4B, TACO1, MRPS7, SNRPC, EIF4A1, TRA2B, NCBP1, RBM46, HNRNPAB, EIF4ENIF1, DPPA5, LUC7L3, YBX1, FYTTD1, SUPT5H, PPP1R8, DCP1B, RBM8A, DXO, RC3H2, NUDT16, AQR, DDX6, CELF4, SAMD4A, SF3B6, DHFR, FXR2, MECP2, RIDA, THOC2, LUC7L, KHDRBS3, CELF2, SLBP, TSN, RC3H1, FUBP1, CELF6, KHNYN, THOC5, EDC3, FUBP3, RBM14, RBM4, LSM14B, UPF3B, AGO2, SCAF8, NCBP3, HNRNPLL, QKI, RBFOX1, NXF1, G3BP2, TPR, ZFP36, NUP98, COPA, ZFP36L1, CSTF3, PCBP2, RBM26, SLC4A1AP, YTHDF2, RBMXL3, RBM24 |
| mRNA binding involved in posttranscriptional gene silencing | molecular function | MARF1 |
| mRNA cap binding | molecular function | EIF3D, AGO2 |
| mRNA CDS binding | molecular function | UNK, RBM24 |
| mRNA guanylyltransferase activity | molecular function | RNGTT |
| mRNA N-acetyltransferase activity | molecular function | NAT10 |
| mu-type opioid receptor binding | molecular function | GNAS, GNAO1, WLS |
| muramyl dipeptide binding | molecular function | NOD2 |
| muscle alpha-actinin binding | molecular function | PALLD, MYOM2, PDLIM1, PDLIM2, PKD2, MYOM3, PKD2L1, NRAP, TTN, MYPN, SYNPO2, PDLIM5, LDB3, PDLIM7, PDLIM4, PDLIM3, MYOM1 |
| MutLalpha complex binding | molecular function | ATR, PCNA, MSH2, MSH6, MUTYH, TREX1 |
| MutLbeta complex binding | molecular function | MCM8, MCM9, MUTYH |
| MutSalpha complex binding | molecular function | MLH1, PMS2, ATR, MCM8, MCM9, MUTYH, TREX1 |
| MutSbeta complex binding | molecular function | MCM8, MCM9, MUTYH |
| mycophenolic acid acyl-glucuronide esterase activity | molecular function | ABHD10 |
| myo-inositol transmembrane transporter activity | molecular function | SLC2A13 |
| myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity | molecular function | IPMK |
| myo-inositol:proton symporter activity | molecular function | SLC2A13 |
| myo-inositol:sodium symporter activity | molecular function | SLC5A1 |
| myosin binding | molecular function | MYRIP, TRAK2, ARFGEF1, DMD, RALA, KIRREL1, GIPC1, ARFGEF2, VEZT, USH2A, MYBPC3, ACTC1, TRIM32, CALD1, TRAK1, LARP6, NPHS1, HAP1, MOBP |
| myosin heavy chain binding | molecular function | MYL12B, MYBPC3, MYL2, CORO1A, NKD2 |
| myosin I binding | molecular function | PYCARD |
| myosin II binding | molecular function | SLC9A3R1, GCSAM, STXBP5, LLGL1, TRIOBP, LLGL2, STXBP5L |
| myosin II head/neck binding | molecular function | LIMCH1 |
| myosin II heavy chain binding | molecular function | MYL4, MYL3 |
| myosin light chain binding | molecular function | MYO19, CXCR4, SPATA6, SPATA6L, MYH8, MYLK2, MYOC |
| myosin light chain kinase activity | molecular function | MYLK, MYLK4, MYLK3, MYLK2 |
| myosin phosphatase activity | molecular function | PPP1CB, MYH3, MYH6, MYH8 |
| myosin phosphatase regulator activity | molecular function | DMPK, PPP1R16B, PPP1R16A |
| myosin tail binding | molecular function | SPTBN5 |
| myosin V binding | molecular function | FUS, RAB11A, RAB27A, RAB6B, RAB3C, RAB6A, RAB25, RAB27B, RAB3B, RAB14, RAB11B, NPC1L1, RAB8A, RAB3D |
| myosin VI binding | molecular function | LMTK2 |
| myosin VI light chain binding | molecular function | IQGAP3 |
| myosin-light-chain-phosphatase activity | molecular function | PPP1CB |
| myristoyl-CoA hydrolase activity | molecular function | ACAA2, BAAT, THEM5, THEM4, ACOT7, ACOT2, ACOT11, ACOT4 |
| myristoyl-[acyl-carrier-protein] hydrolase activity | molecular function | OLAH, FASN |
| myristoyltransferase activity | molecular function | NMT1 |
| N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity | molecular function | PAOX |
| N(6)-L-threonylcarbamoyladenine synthase activity | molecular function | OSGEP |
| N,N-dimethylaniline monooxygenase activity | molecular function | FMO3, FMO4, FMO1 |
| N-(long-chain-acyl)ethanolamine deacylase activity | molecular function | NAAA |
| N-acetyl-beta-D-galactosaminidase activity | molecular function | HEXD |
| N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | B4GALNT3, B4GALNT4 |
| N-acetyl-L-aspartate-L-glutamate ligase activity | molecular function | RIMKLB, RIMKLA |
| N-acetylgalactosamine 4-O-sulfotransferase activity | molecular function | CHST9, CHST13, CHST14, CHST8, CHST11 |
| N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity | molecular function | CHST15, CHST11 |
| N-acetylgalactosamine kinase activity | molecular function | GALK2 |
| N-acetylgalactosamine-4-sulfatase activity | molecular function | ARSB, GALNS |
| N-acetylgalactosamine-6-phosphate deacetylase activity | molecular function | AMDHD2 |
| N-acetylgalactosamine-6-sulfatase activity | molecular function | GALNS |
| N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity | molecular function | CHSY1, CHSY3, CHPF |
| N-acetylglucosamine 6-O-sulfotransferase activity | molecular function | CHST6, CHST4, CHST5, CHST2, CHST3, CHST7 |
| N-acetylglucosamine kinase activity | molecular function | NAGK |
| N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity | molecular function | NAGPA |
| N-acetylglucosamine-6-phosphate deacetylase activity | molecular function | AMDHD2 |
| N-acetylglucosamine-6-sulfatase activity | molecular function | SGSH, GNS, SULF1, SULF2 |
| N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity | molecular function | EXT1, EXT2 |
| N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity | molecular function | ALG13 |
| N-acetylglucosaminylphosphatidylinositol deacetylase activity | molecular function | PIGL |
| N-acetyllactosamine synthase activity | molecular function | B4GALT2, B4GALT4, B4GALT3, B4GALT1, B4GALT5 |
| N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity | molecular function | GCNT2 |
| N-acetylmuramoyl-L-alanine amidase activity | molecular function | PGLYRP4, PGLYRP2 |
| N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity | molecular function | CASD1 |
| N-acetylneuraminate lyase activity | molecular function | NPL |
| N-acetylneuraminate synthase activity | molecular function | NANS |
| N-acetylphosphatidylethanolamine-hydrolysing phospholipase activity | molecular function | NAPEPLD |
| N-acetyltransferase activity | molecular function | NAA20, NAT14, SAT1, SMARCE1, NAT1, SATL1, SAT2, NAT8L, NAA40, NAA50, NAA30, NAT16, ESCO1, NAA80, NAT8, GNPNAT1, ELP3, KAT2A, NAA10, KAT2B, KAT14, AANAT, NAT10, NAA60 |
| N-acylglucosamine 2-epimerase activity | molecular function | RENBP |
| N-acylmannosamine kinase activity | molecular function | GNE |
| N-acylneuraminate cytidylyltransferase activity | molecular function | CMAS, NANS |
| N-acylneuraminate-9-phosphatase activity | molecular function | NANP |
| N-acylneuraminate-9-phosphate synthase activity | molecular function | NANS |
| N-acylphosphatidylethanolamine-specific phospholipase D activity | molecular function | PLD1, NAPEPLD, PLD2 |
| N-acylsphingosine galactosyltransferase activity | molecular function | UGT8 |
| N-acyltransferase activity | molecular function | GLYATL1, PLAAT1, PLAAT3, GLYAT, CERS5, BAAT, PLAAT5, CERS4, CERS1, CERS6, CERS3 |
| N-box binding | molecular function | HES1, HES4 |
| N-formyl peptide receptor activity | molecular function | FPR1, FPR3, FPR2 |
| N-formylglutamate deformylase activity | molecular function | NAALAD2 |
| N-methyltransferase activity | molecular function | HNMT, PRMT1, HEMK1, INMT, NNMT |
| N-retinylidene-phosphatidylethanolamine flippase activity | molecular function | ABCA4 |
| N-sulfoglucosamine sulfohydrolase activity | molecular function | SGSH |
| N-terminal myristoylation domain binding | molecular function | CALM1, CALM2, CALM3 |
| N-terminal protein N-methyltransferase activity | molecular function | NTMT1 |
| N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity | molecular function | PAOX |
| N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity | molecular function | PAOX |
| N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity | molecular function | SMOX |
| N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity | molecular function | ASRGL1, AGA |
| N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity | molecular function | ADSL |
| N6-isopentenyladenosine methylthiotransferase activity | molecular function | CDK5RAP1 |
| N6-methyladenosine-containing RNA binding | molecular function | YTHDF1, YTHDC1, DHX36, HNRNPC, YTHDF3, HNRNPA2B1, YTHDF2 |
| N6-threonylcarbomyladenosine methylthiotransferase activity | molecular function | CDKAL1 |
| NAADP-sensitive calcium-release channel activity | molecular function | MCOLN3, TPCN2, MCOLN1, MCOLN2, TPCN1 |
| NACHT domain binding | molecular function | CARD8, TRIM16 |
| NAD binding | molecular function | GAPDH, PARP1, GAPDHS, IDH1, LDHA, HIBADH, ADH4, GRHPR, MDH1, SORD, UGDH, NDUFS2, ME1, GLYR1, CTBP2, NNT, HPGD, NUDT6, HADHA, IDH3B, BDH2, ALDH2, AHCY, IDH2, GPD1L, IDH3G, CTBP1, PHGDH, CYB5R3, IDH3A, ALDH1A1, AOX1, ME2, ME3, HSD11B2 |
| NAD DNA ADP-ribosyltransferase activity | molecular function | PARP3 |
| NAD transmembrane transporter activity | molecular function | SLC25A17 |
| NAD(P)+ nucleosidase activity | molecular function | CD38, IL1R1, IL1RAP, SARM1, IL18RAP, TLR1, TLR10, IL1RL1, BST1, IL1RL2, TLR6 |
| NAD(P)+ transhydrogenase (B-specific) activity | molecular function | NNT |
| NAD(P)+ transhydrogenase activity | molecular function | NNT, DHDH |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | molecular function | ART3, ART4, SIRT6, ART5, ART1 |
| NAD(P)H dehydrogenase (quinone) activity | molecular function | CBR4, NQO1, NQO2 |
| NAD(P)H oxidase (H(2)O(2)-forming activity | molecular function | AIFM1, CYB5R4, DUOX2, MICAL2, MICAL1, DUOX1 |
| NAD+ ADP-ribosyltransferase activity | molecular function | PARP1, PARP2, ART3, SIRT5, TNKS, ART4, SIRT4, ZC3HAV1, PARP12, PARP14, TIPARP, SIRT2, PARP3, PARP16, TNKS2, TRPT1, PARP6, SIRT6, PARP8, ART5, PARP4, PARP11, PARP10, ART1 |
| NAD+ binding | molecular function | GLUD1, SIRT5, HADH, SIRT4, ZC3HAV1, PARP14, CRYL1, HPGD, SIRT2, ALDH1A3, UXS1, SIRT6, SIRT7 |
| NAD+ diphosphatase activity | molecular function | NUDT12 |
| NAD+ kinase activity | molecular function | DGKK, NADK2, SPHK2, DGKE, NADK, DGKB, DGKI, DGKA, DGKG, DGKZ, CERK, DGKH, DGKQ, DGKD, AGK |
| NAD+ nucleosidase activity | molecular function | CD38, SARM1, BST1 |
| NAD+ nucleotidase, cyclic ADP-ribose generating | molecular function | CD38, IL1R1, IL1RAP, SARM1, IL18RAP, TLR1, TLR10, IL1RL1, BST1, IL1RL2, TLR6 |
| NAD+ synthase (glutamine-hydrolyzing) activity | molecular function | NADSYN1 |
| NAD-dependent histone deacetylase activity | molecular function | SIRT2, SIRT6 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) | molecular function | HDAC4, HDAC11, HDAC2, HDAC9, HDAC8, HDAC7, HDAC3, HDAC6, HDAC5 |
| NAD-dependent histone deacetylase activity (H3-K18 specific) | molecular function | SIRT7 |
| NAD-dependent histone deacetylase activity (H3-K9 specific) | molecular function | SIRT6 |
| NAD-dependent histone deacetylase activity (H4-K16 specific) | molecular function | SIRT2 |
| NAD-dependent protein deacetylase activity | molecular function | SIRT5, SIRT4, SIRT2, SIRT6, SIRT7 |
| NADH binding | molecular function | HSD17B8, CRYZ, QDPR, RNLS |
| NADH dehydrogenase (ubiquinone) activity | molecular function | MT-ND4, NDUFC2, MT-ND5, NDUFA6, NDUFB9, NDUFA4, NDUFB5, NDUFS6, NDUFB6, NDUFAF2, NDUFC1, NDUFS4, NDUFA8, NDUFB8, NDUFS2, NDUFB10, NDUFA1, NDUFA2, WDR93, NDUFB1, NDUFS1, NDUFB4, NDUFA12, NDUFA5, NDUFAB1, NDUFA7, NDUFC2-KCTD14, NDUFA3, NDUFV2, NDUFA9, NDUFV3, NDUFB2, NDUFS8, NDUFB7, NDUFA10, MT-ND4L, MT-ND6, NDUFS5, NDUFS7, MT-ND1 |
| NADH dehydrogenase activity | molecular function | MT-ND5, NDUFB8, NDUFS2, NDUFB1, NDUFA9, NDUFS8, NDUFB7, NDUFS7 |
| NADH pyrophosphatase activity | molecular function | NUDT15, ITPA, ENPP3, ENPP1, NUDT6, NUDT17, NUDT12 |
| NADHX epimerase activity | molecular function | APOA1BP, YJEFN3 |
| NADP binding | molecular function | NOS3, MTHFR, MTRR, GSR, GAPDH, CAT, NOS2, GAPDHS, IDH1, G6PD, NOX5, NOX1, GRHPR, DHFR2, ME1, POR, GLYR1, HMGCR, NNT, SPR, PGD, HSD11B1, FMO3, CRYZL1, DHFR, H6PD, NDOR1, TM7SF2, DPYD, FMO4, DHCR7, ASPDH, DUOX1, FMO1 |
| NADP+ binding | molecular function | GMDS, ME3 |
| NADP-retinol dehydrogenase activity | molecular function | AKR1C3, AKR1B1, DHRS3, RDH14, AKR1B10, RDH13, RDH10, RDH11, RDH12, RDH8 |
| NADPH binding | molecular function | MTRR, SRD5A1, DECR1, KCNAB1, LBR, GRHPR, CBR3, TP53I3, CBR4, HMGCR, FASN, DHFR, DUS2, CRYZ, QDPR |
| NADPH dehydrogenase (quinone) activity | molecular function | CBR4 |
| NADPH-hemoprotein reductase activity | molecular function | MTRR, POR, NDOR1 |
| NADPH:quinone reductase activity | molecular function | ADH4, TP53I3, CRYZL1, CRYZ |
| NADPH:sulfur oxidoreductase activity | molecular function | MICAL2 |
| NADPHX epimerase activity | molecular function | APOA1BP, YJEFN3 |
| natriuretic peptide receptor activity | molecular function | GUCY2F, NPR3, NPR1, GUCY2D, NPR2 |
| natural killer cell lectin-like receptor binding | molecular function | HLA-E, MICB, RAET1E, ULBP3, ULBP2, ULBP1 |
| NEDD8 activating enzyme activity | molecular function | NAE1, UBA3 |
| NEDD8 conjugating enzyme activity | molecular function | UBE2F |
| NEDD8 ligase activity | molecular function | RBX1 |
| NEDD8 transferase activity | molecular function | UBA3, UBE2F, UBE2M, RBX1 |
| NEDD8-specific protease activity | molecular function | COPS5, COPS4, OTUB2, SENP8, USP21 |
| nerve growth factor binding | molecular function | NTRK1, PCSK6, SORT1, NGFR, FURIN |
| nerve growth factor receptor activity | molecular function | NTRK1, SORT1 |
| nerve growth factor receptor binding | molecular function | NGF, BEX3, NTF4, NTF3 |
| netrin receptor activity | molecular function | DCC, UNC5C, UNC5D, UNC5CL, UNC5B, UNC5A |
| netrin receptor activity involved in chemorepulsion | molecular function | UNC5C |
| netrin receptor binding | molecular function | DSCAM |
| neuregulin binding | molecular function | ITGAV, ITGA6, ITGB3, ITGB4, ERBB3 |
| neuregulin receptor activity | molecular function | RTN4R, ERBB3 |
| neurexin family protein binding | molecular function | NLGN4X, SYTL4, NLGN2, SYTL3, NLGN4Y, SYTL2, CASK, CPE, SYTL1, LRRTM2 |
| neurohypophyseal hormone activity | molecular function | OXT, AVP |
| neuroligin family protein binding | molecular function | NRXN1, SNTG2, NRXN2, NRXN3, DLG4 |
| neuromedin B receptor binding | molecular function | NMB |
| neuromedin U binding | molecular function | NMUR2, NMUR1 |
| neuromedin U receptor activity | molecular function | NMUR2, NMUR1 |
| neuromedin U receptor binding | molecular function | NMU |
| neuropeptide binding | molecular function | KISS1R, MCHR1, MRGPRX2, OPRD1, NPBWR1, SORL1, PTGDR2, SSTR4, SSTR3, ADCYAP1R1, GALR1, OPRL1, SSTR5, NPBWR2, GPR1, OPRK1, MC3R |
| neuropeptide hormone activity | molecular function | TRH, OXT, ASIP, QRFP, GRP, NPY, CRH, NTS, CORT, UCN, NPFF, NMB, CARTPT, AVP, HCRT, CCK, CALCB, VGF, ECRG4, GAL, PRLH, PYY, PENK |
| neuropeptide receptor activity | molecular function | KISS1R, PRLHR, MCHR1, SORCS3, NPFFR2, SORCS2, NPBWR1, NMUR2, NMUR1, SORCS1, NPBWR2, GPR139 |
| neuropeptide receptor binding | molecular function | NTS |
| neuropeptide Y receptor activity | molecular function | PROKR2, GPR83, PRLHR, QRFPR, NPY1R, PROKR1, NPY5R |
| neuropilin binding | molecular function | VEGFA, SEMA7A, SEMA3A, PXN, TAOK2, ABL1 |
| neurotensin receptor activity, non-G protein-coupled | molecular function | SORT1 |
| neurotransmitter binding | molecular function | SLC6A6, GRIN1, SLC6A11, NIPSNAP1, SLC6A12, GRIN3B, SLC6A13 |
| neurotransmitter receptor activity | molecular function | GABRB1, CHRNA5, GABRA2, CHRNE, P2RY11, HTR3B, HTR3A, HRH1, HTR7, CHRNA2, GABRG2, GABRB3, GLRA3, CHRNB1, GABRA5, CHRM3, CHRNA7, CHRND, CHRFAM7A, CHRNA10, GABRB2, GABRA4, GABRG1, CHRNA3, HTR1E, HRH4, GABRP, GABRD, HTR3E, GLRA1, HTR2C, CHRNA6, OR10H1, HTR1B, HRH3, GABRR2, CHRNG, CHRM4, CHRM1, GABRA1, GRIN3B, CHRM5, CHRNB2, HRH2, GABRA3, CHRNA4, HTR5A, ZACN, GABRQ, OR10H2, GABRR3, CHRM2, HTR6, GABRG3, CHRNA1, DRD4, GLRA2, CHRNB4, HTR2B, OR5T2 |
| neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration | molecular function | GRIA1, GRM5, GRM1 |
| neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | molecular function | CHRM1 |
| neurotransmitter transmembrane transporter activity | molecular function | SLC28A2, SLC22A2, SLC6A2, CPLX1, SLC6A15, SLC6A16, SLC17A6, SLC29A2, SLC6A4, SLC29A1, GABRQ, SLC6A3, SLC22A1, SLC22A3, CPLX3, SLC17A7 |
| neurotransmitter:sodium symporter activity | molecular function | SLC6A14, SLC6A20, SLC6A8, SLC6A2 |
| neurotrophin binding | molecular function | NTRK1, NTRK2, NGFR |
| neurotrophin p75 receptor binding | molecular function | NTRK1 |
| neurotrophin receptor activity | molecular function | NTRK1, NTRK2 |
| neurotrophin receptor binding | molecular function | NTF3 |
| neurotrophin TRKA receptor binding | molecular function | PIK3R1, SHC1, EFNA5, GRB2, FRS2 |
| neurotrophin TRKB receptor binding | molecular function | BDNF, EFNA5 |
| neurotrophin TRKC receptor binding | molecular function | EFNA5 |
| neutral amino acid transmembrane transporter activity | molecular function | SLC7A5, SLC1A5, SLC36A1, SLC38A1, SLC1A4, SLC7A8, SLC7A9, SLC43A1, SLC3A2, SLC6A19, SLC7A10, SLC43A2 |
| neutral amino acid:sodium symporter activity | molecular function | SLC38A1, SLC38A2 |
| neutral sphingomyelin phosphodiesterase activity | molecular function | SMPD3 |
| NF-kappaB binding | molecular function | CDKN2A, GSK3B, APEX1, TAF4B, ANXA4, NPM1, BCL10, HDAC2, PPARD, TP53BP2, AKAP8, CDK5RAP3, SETD6, PSMA6, RELA, NFKBIA, EP300, COMMD6, CPNE1, FAF1, HDAC3, HIF1AN, BRMS1 |
| NF-kappaB-inducing kinase activity | molecular function | ALK, IRAK1, IKBKE, PPP4C, MAP3K14, RIPK3 |
| NFAT protein binding | molecular function | GATA4, MAPK14, SPI1, PPARA |
| nickel cation binding | molecular function | CA3 |
| nicotinamide N-methyltransferase activity | molecular function | NNMT |
| nicotinamide phosphoribosyltransferase activity | molecular function | NAMPT |
| nicotinamide-nucleotide adenylyltransferase activity | molecular function | NMNAT1, NMNAT3, NMNAT2 |
| nicotinate phosphoribosyltransferase activity | molecular function | NAPRT |
| nicotinate transmembrane transporter activity | molecular function | SLC22A13 |
| nicotinate-nucleotide adenylyltransferase activity | molecular function | NMNAT1, NMNAT3, ABL1, NMNAT2 |
| nicotinate-nucleotide diphosphorylase (carboxylating) activity | molecular function | NAMPT, NAPRT, QPRT |
| nicotinic acid receptor activity | molecular function | HCAR2 |
| nitrate reductase activity | molecular function | MTARC2, GPHN, MTARC1 |
| nitrate transmembrane transporter activity | molecular function | AQP6 |
| nitric oxide binding | molecular function | GSTP1, CBS, THAP4 |
| nitric oxide dioxygenase activity | molecular function | POR |
| nitric oxide transmembrane transporter activity | molecular function | AQP1 |
| nitric-oxide synthase activity | molecular function | NOS3, NOS2 |
| nitric-oxide synthase binding | molecular function | CTNNB1, ACTB, CD74, DMD, NOS1AP, DNM3, CAV3, CALM3, SLC6A4, DNM1, SNTA1, SCN5A, CAV1 |
| nitric-oxide synthase regulator activity | molecular function | EGFR, ESR1, HSP90AA1, AKT1, CALM3 |
| nitrilase activity | molecular function | NIT1 |
| nitrite reductase (NO-forming) activity | molecular function | CBS |
| NMDA glutamate receptor activity | molecular function | GRIN1, GRIN2C, GRIN2B, GRIN3A, GRIN2A, GRIN3B, GRIN2D, PTK2B |
| nociceptin receptor activity | molecular function | OPRL1 |
| nodal binding | molecular function | TDGF1, ACVR1C, CFC1B |
| non-membrane spanning protein tyrosine kinase activity | molecular function | TYK2, WEE1, YES1, SRC, JAK2, DYRK1A, PEAK1, BAZ1B, PTK2, SYK, ITK, ZAP70, SRMS, TEC, MELK, JAK1, TNK1, RIPK2, ABL1, FER, CLK1, LYN, PRKCD, ABL2, BTK, FGR, EIF2AK2, SLA, HCK, LCK, CSK, FRK, FES, MATK, JAK3, PTK6, PKDCC, PTK2B, TXK, BLK |
| non-membrane spanning protein tyrosine phosphatase activity | molecular function | ACP1, PTPN11, DUSP22, PTPN2, PTPN22, PTPN9, PTPN12, PTPN18, PTPN4 |
| non-sequence-specific DNA binding, bending | molecular function | SAP30L |
| norepinephrine binding | molecular function | ADRB2, ADRB3, ADRA2A, ADRB1, DRD4 |
| norepinephrine:sodium symporter activity | molecular function | SLC6A2, SLC6A3, SLC22A1 |
| norspermine:oxygen oxidoreductase activity | molecular function | SMOX |
| Notch binding | molecular function | MEGF10, NOTCH2NLA, SNED1, NOTCH1, DTX1, AAK1, NCOR2, SNW1, NOTCH4, KCTD10, HIF1AN, CCN3, GALNT11, DLL1, CHAC1, JAG2, DLK2, JAG1, DNER, CNTN6, DLL3 |
| nuclear export signal receptor activity | molecular function | XPO4, XPO1, EIF4ENIF1, RAN, XPO7, CSE1L, XPO6, NUP42, NUP214 |
| nuclear hormone receptor binding | molecular function | NRIP1, HIF1A, CTNNB1, NCOA2, TCF7L2, BUD31, NCOA3, TACC2, SMARCD3, TAF1, EP300, NCOA1, NCOR2, SNW1, CRY1, BCAS3, NCOR1, CRX, JUP, MYOD1, ACTN4, NCOA7 |
| nuclear import signal receptor activity | molecular function | KPNA4, KPNA2, HIKESHI, IPO11, KPNA5, IPO9, IPO4, KPNA3, KPNA6, TMCO6, IPO5, TNPO3, TNPO1, KPNA1, SNUPN, RANBP6, NUTF2, TNPO2 |
| nuclear localization sequence binding | molecular function | KPNA4, KPNA2, BRAP, POM121, KPNA5, NUP58, NPAP1, IPO4, KPNA3, KPNA6, NUP153, IPO5, NFKBIA, POM121L2, TNPO1, KPNA1, NUP98, CABP1, RANBP6, TNPO2, NUP214 |
| nuclease activity | molecular function | RAG1, ERCC1, PMS2, APEX1, DROSHA, DICER1, RNASET2, EXOSC10, MEIOB, ANKLE1, DDX1, RBBP8, FAN1, G3BP1, LACTB2, EXO5, FEN1, ASTE1, ZC3H12A, SLX1A, CNOT8, PARN, TATDN1, RNASE11, STK31, ERI2, ISG20, CPSF3, REXO2, RNASE4, ENDOV, AEN, DNASE2B, PLD4, MGME1, PELO, XRN2, ELAC1, APEX2, REXO5, MUS81, DCLRE1C, ELAC2, REXO4, AGO3, PXDNL, RNASE2, ERCC5, PPP1R8, ENDOG, PAN2, EXO1, RNASEL, TDP1, DXO, PGAP1, ERI1, REXO1, EXD3, DCLRE1B, PRORP, MRE11, SMG6, NOB1, RAD9A, RAD1, YBEY, TSN, ZRANB3, XRN1, DIS3, TDP2, PNPT1, AGO2, ERI3, GEN1, CNOT6L, TRIR, ERCC4, RNASE6, EXD2, DFFB, RNASE3, USB1, RNASEH2A, DNASE2, DNASE1L3, MRPL44, DIS3L, TSEN15, TATDN2, TSEN2, ANG, DNASE1, DIS3L2, HARBI1, TREX1, ZC3H12D, RNASEH1, POLD1, SND1, PLD3, EME2, ISG20L2, DNASE1L1, PGBD5, RNASE7, EXOG |
| nucleic acid binding | molecular function | DDX3Y, RAG1, WT1, FMR1, DAZ2, DAZ4, DAZ1, ZEB2, SP1, ERCC2, CTCFL, PEG3, PLAGL1, POLQ, PIWIL2, DAZL, PIWIL1, ZFP37, PABPC1, POLG, KHDRBS1, PABPC1L, LIN28B, PABPC3, ZDBF2, DDX4, DAZ3, RBMY1A1, ZNF331, DDX25, DICER1, HNRNPL, SRSF4, SRSF9, SRSF6, PIWIL4, BOLL, TDRD9, PRDM9, RBMX2, RBMX, EXOSC10, ZNF174, PIWIL3, PATZ1, ZNF230, YBX2, RBFOX2, SYNJ1, HNRNPCL1, CSTF2, FUS, MATR3, HNRNPF, PCBP4, EWSR1, HNRNPA0, ZNF667, ZNF549, ZNF790, ZNF440, ZNF454, HELQ, PPIL4, ZCCHC13, DDX1, ZNF669, SPEN, ZNF350, TUT1, ZNF302, ZNF586, POLR1H, TBK1, FAN1, DDX3X, REV3L, NPM1, SNRNP70, YBX3, HNRNPM, NCBP2, G3BP1, ZNF638, KARS1, ZNF385B, SUGP2, DHX40, TRMT2A, ZNF615, ZCCHC14, NEIL1, MTERF1, ZNF700, DDX47, ZNF430, DDX43, ZNF492, DBF4, DDX19B, NOVA2, TDRKH, IGF2BP2, RBM47, HNRNPR, NARS1, CNOT4, HNRNPA1, RBMS1, FXR1, HNRNPA3, ZNF136, RPS18, ZNF33A, ZNF33B, GRSF1, EIF4A2, R3HDM1, TIGD7, ZNF620, DDX46, POGZ, BRAP, MEX3D, ZNF786, CELF5, ZNF671, THAP6, ZNF398, SRSF12, PSPC1, RBM41, ZNF385A, RBM15, SRSF8, DHX36, ZNF160, AGO4, A1CF, RBM22, CNOT |
| nucleic acid transmembrane transporter activity | molecular function | SIDT2 |
| nucleobase transmembrane transporter activity | molecular function | SLC23A1, SLC23A2 |
| nucleobase-containing compound kinase activity | molecular function | AK2, AK4, AK1, AK9, CMPK1, AK3, AK8, AK7 |
| nucleoside binding | molecular function | PNP, CDA, ACTN4 |
| nucleoside diphosphate kinase activity | molecular function | NME8, NME7, NME5, NME9, AK4, AK1, AK9, CMPK1, NME6, NME2, AK8, NME3, AK7, NME1, NME4, DTYMK |
| nucleoside kinase activity | molecular function | UCK1, UCK2, TK2 |
| nucleoside monophosphate kinase activity | molecular function | AK6, AK4, AK9 |
| nucleoside transmembrane transporter activity | molecular function | SLC28A2, SLC28A1, SLC29A2, SLC29A1, SLC29A3, SLC28A3 |
| nucleoside-diphosphatase activity | molecular function | NUDT5, NUDT15, ENTPD5, CANT1, ENTPD4, ENTPD8, ENTPD2, ENTPD3 |
| nucleoside-triphosphatase activity | molecular function | DDX3X, NTPCR, DHX29, ENTPD8, ENTPD2, ENTPD3 |
| nucleoside-triphosphate diphosphatase activity | molecular function | NUDT15, ITPA, DCTPP1, ENPP3, ENPP1 |
| nucleoside:sodium symporter activity | molecular function | SLC28A2, SLC28A1, SLC28A3 |
| nucleosomal DNA binding | molecular function | MBD2, MTA2, ACTB, HMGN1, H1-4, HMGN4, HMGN3, ACTL6A, HNRNPC, SMARCA4, HDAC2, SMARCE1, H2AZ1, H1-2, HMGA2, SMARCB1, H1-8, SMARCC2, RBBP4, CHD4, MACROH2A1, HMGN5, H1-0, SMARCC1, RCC1, MBD3, H1-5, H1-1, H1-3, GATAD2B, HMGN2, H3-3A |
| nucleosomal histone binding | molecular function | SPHK2, L3MBTL1, UHRF1 |
| nucleotidase activity | molecular function | NT5C, NT5M |
| nucleotide binding | molecular function | DDX3Y, EGFR, MYH7, LIG4, GNAS, DAZ2, AMHR2, TSSK4, DAZ4, TSSK6, DAZ1, AURKC, ERBB2, CDK1, HSP90AA1, ABCB1, MTHFD1, CFTR, FLT1, ERCC2, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, HSPA4, KDR, GSK3B, UBE2B, ADCY2, ATM, PANK2, CHD2, POLQ, GNAO1, FGFR1, PRPS2, CSNK2A2, ABCC1, HSPA9, MTOR, VDAC2, HSPA2, GNAI1, BRSK2, DAZL, TUBB2B, MSH4, MSH5, INSR, PGK2, YES1, IGF1R, KIT, HSPA5, PABPC1, SRC, CHKA, PIK3CA, MAPK8, ATR, BMPR2, PABPC1L, LMTK2, APOA1BP, PABPC3, DDX4, DAZ3, CDC7, PDXK, RAF1, RBMY1A1, HSPA1A, HSPA1B, HSPD1, MAK, HSPA1L, CLK3, CDK9, ACTB, CDC42, RAP1A, TUBB3, 39326, H1FNT, 41153, DNAH9, CHD7, DDX25, DICER1, DNM1L, KIF3B, SLC22A5, PGK1, NTRK1, TOP2A, HNRNPL, TUBA4A, SRSF4, DDR1, SRSF9, SRSF6, TUBA3C, CAMK4, KIF26B, MAST2, PPIP5K1, KIF6, DNAH12, BOLL, DYNC2H1, TDRD9, MYO19, ADCY10, MOV10L1, THG1L, TUBA8, DNAH1, STARD9, RABL2A, MYO15A, RBMX2, KIF3A, 38231, CKM, RBMX, MSH2, LIMK2, EXOSC10, SPAG1, DMPK, DYNC1H1, MAPK14, NLRP14, DNAH5, DNAH11, TEP1, NXF2, FARS2, DIRAS3, GLUD1, H1-4, HSPA8, ATP2A2, ARF4, P |
| nucleotide diphosphatase activity | molecular function | ENPP2, NUDT15, ITPA, ENPP3, ENPP1, CILP2, CILP |
| nucleotide phosphatase activity, acting on free nucleotides | molecular function | DUSP11, NTPCR, NUDT16, PGP |
| nucleotide-sugar transmembrane transporter activity | molecular function | TMEM241, SLC35D2, SLC35E3 |
| nucleotidyltransferase activity | molecular function | TERT, POLQ, POLG, UAP1, THG1L, GALT, UGP2, YRDC, CMAS, TUT1, POLR1B, NMNAT1, REV1, REV3L, RNGTT, PAPOLA, FICD, POLH, TRNT1, NUDT5, OAS1, TENT5C, MTPAP, EIF2B3, MOCS3, TENT5A, NMNAT3, POLK, POLR2B, PAPOLB, POLR1A, OASL, RPAP1, PCYT1B, POLRMT, POLR3A, TAMM41, TENT2, PCYT2, PAPOLG, CDS1, TENT5D, PNPT1, POLI, PAPSS2, TENT4B, CGAS, CHRAC1, PRIM1, POLE, TUT4, TENT4A, TENT5B, COASY, CTU1, GMPPA, POLB, GMPPB, POLL, POLR2A, POLD1, CTU2, NMNAT2, SELENOO, CRPPA, PCYT1A, POLN, PRIMPOL, DNTT, OAS2, TUT7, FLAD1, POLR3B, POLA1 |
| O-acetyl-ADP-ribose deacetylase activity | molecular function | OARD1, ADPRS |
| O-acyltransferase activity | molecular function | MOGAT1, LCLAT1, PLAAT1, PLA2G4C, GNPAT, DGAT2, HHAT, DGAT1, SOAT1, PLA2G4A, PLA2G15, GPAM, DGAT2L6, PIGW, MOGAT2, MOGAT3, LCAT |
| O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity | molecular function | MFNG, LFNG |
| O-methyltransferase activity | molecular function | COMT, COQ3, HENMT1, MEPCE, LRTOMT |
| O-phospho-L-serine:2-oxoglutarate aminotransferase activity | molecular function | PSAT1 |
| odorant binding | molecular function | OR5AR1, OR9Q2, OR6B3, OR10Q1, OR5P2, OR5B21, OR5F1, OR5I1, OR8D4, OR13A1, OR5R1, OR5K1, OBP2A, OR5C1, OBP2B, OR8G1, OR9Q1, OR5AC2, OR5P3, OR8D2 |
| oleamide hydrolase activity | molecular function | FAAH2, FAAH |
| oleate transmembrane transporter activity | molecular function | MFSD2A |
| oleic acid binding | molecular function | SCP2, FABP3 |
| oleoyl-[acyl-carrier-protein] hydrolase activity | molecular function | OLAH, FASN |
| olfactory receptor activity | molecular function | OR2W3, OR12D2, OR2AG2, OR10AD1, OR5AR1, OR52D1, OR5V1, OR9A4, OR51A7, OR1G1, OR9Q2, OR51V1, OR52A1, OR1L6, OR1N2, OR6B3, OR10J1, OR1D5, OR10A3, OR2T33, OR52E4, OR2H1, OR2J2, OR56A4, OR10Q1, OR13C4, OR2T4, OR4X1, OR5P2, OR2M4, OR4C12, OR5B21, OR5F1, OR5I1, OR2L13, OR4D11, OR8D4, OR13A1, OR13C8, OR5R1, OR5K1, OR52B2, OR51B6, OR51B5, OR2S2, OR7C2, OR3A1, OR10A4, OR2A4, OR1E1, OR2W1, OR10H1, OR7C1, OR2A14, OR10A5, OR51I2, OR10H2, OR5C1, OR2T1, OR1C1, OR8G1, OR9Q1, OR1F1, OR2Z1, OR2T6, OR5AC2, OR6C68, OR4K17, OR5T2, OR5P3, OR8D2 |
| olfactory receptor binding | molecular function | RTP5, REEP1, RTP3, RTP1 |
| oligo-1,6-glucosidase activity | molecular function | GAA, SI |
| oligopeptidase activity | molecular function | MME, PREP |
| oligopeptide transmembrane transporter activity | molecular function | SLC15A4, SLC15A2, SLC15A1 |
| oligosaccharide binding | molecular function | REG3A, REG1B, LOXL2, REG3G, COLEC11, SELP, ITLN1, CHID1, SELL |
| oligosaccharyl transferase activity | molecular function | ALG5, STT3B, STT3A |
| omega peptidase activity | molecular function | APEH, GGH, UCHL1 |
| omega-6 fatty acid desaturase activity | molecular function | FADS1 |
| oncostatin-M receptor activity | molecular function | IL6ST, LIFR, OSMR |
| oncostatin-M receptor binding | molecular function | OSM |
| open rectifier potassium channel activity | molecular function | KCNK3 |
| opioid peptide activity | molecular function | CDC42EP2, PDYN, PENK |
| opioid receptor activity | molecular function | OGFR, OGFRL1, OPRD1, NPBWR1, SIGMAR1, OPRL1, NPBWR2, OPRK1 |
| opioid receptor binding | molecular function | NPFFR2, PDYN, PENK |
| opsin binding | molecular function | SAG, PRCD |
| opsonin binding | molecular function | ITGAV |
| orcinol O-methyltransferase activity | molecular function | LRTOMT |
| orexigenic neuropeptide QRFP receptor binding | molecular function | QRFP |
| orexin receptor activity | molecular function | HCRTR1 |
| organic acid binding | molecular function | HBG2, HMGCS1, HBD, HBB, HBZ, HBQ1, HBA1 |
| organic acid:sodium symporter activity | molecular function | SLC13A3, SLC5A8, SLC5A12 |
| organic anion transmembrane transporter activity | molecular function | SLC17A3, SLCO1B3, ABCC11, MFSD10, SLC22A7, SLCO1A2, SLCO2B1, ABCC5, SLC22A11, SLC22A3, SLCO1C1 |
| organic cation transmembrane transporter activity | molecular function | SLC22A2, SLC7A8, SLC22A16, SLC22A1, SLC22A3 |
| organic cyclic compound binding | molecular function | RYR2, MTNR1A, SLC16A1 |
| ornithine decarboxylase activator activity | molecular function | PRLR, AZIN1, AZIN2 |
| ornithine decarboxylase activity | molecular function | ODC1, AZIN1, AZIN2 |
| ornithine decarboxylase inhibitor activity | molecular function | OAZ3, OAZ1, OAZ2 |
| ornithine(lysine) transaminase activity | molecular function | OAT |
| ornithine-oxo-acid transaminase activity | molecular function | OAT |
| orotate phosphoribosyltransferase activity | molecular function | UMPS |
| orotidine-5'-phosphate decarboxylase activity | molecular function | UMPS |
| osmolarity-sensing cation channel activity | molecular function | TMEM63A, TMEM63C, TMEM63B |
| outward rectifier potassium channel activity | molecular function | KCNK2, PKD2, KCNT2, KCNK18, KCNA2, KCNA3, KCNT1 |
| oxalate transmembrane transporter activity | molecular function | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC26A2, SLC26A1, SLC26A10, SLC26A6 |
| oxaloacetate decarboxylase activity | molecular function | ME1, FAHD1, ME2, ME3 |
| oxaloacetate transmembrane transporter activity | molecular function | SLC25A10 |
| oxidative DNA demethylase activity | molecular function | ALKBH4, ALKBH1 |
| oxidative phosphorylation uncoupler activity | molecular function | UCP3, UCP1, UCP2 |
| oxidative RNA demethylase activity | molecular function | ALKBH1, ALKBH5 |
| oxidised low-density lipoprotein particle receptor activity | molecular function | CD36 |
| oxidized purine DNA binding | molecular function | OGG1, MSH2, RPS3, MSH6, MUTYH, RECQL4 |
| oxidized purine nucleobase lesion DNA N-glycosylase activity | molecular function | OGG1, NTHL1 |
| oxidized pyrimidine DNA binding | molecular function | RPS3 |
| oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity | molecular function | NTHL1, SMUG1 |
| oxidoreductase activity | molecular function | SOD1, CYP1A1, CYP19A1, HSD17B1, PTGS1, NOS3, SRD5A2, PTGS2, HSD17B4, PLOD1, CYP24A1, SOD2, CYP17A1, CYP1A2, HMOX1, MTHFD1, CYP2B6, HSD17B3, MTHFR, MTRR, GSR, GAPDH, CYP11A1, GPX1, HSD3B1, CYP11B1, SRD5A1, HSD3B2, GPX4, HSD17B2, AKR1C3, PRDX4, DECR1, CAT, LPO, NOS2, XDH, PPOX, GAPDHS, IDH1, LDHC, CYP21A2, G6PD, CYP11B2, APEX1, PRDX2, CYP1B1, CYP26B1, ALDH1A2, MT-CO1, KDM5C, PRDX1, KDM5D, MT-CYB, LDHA, MT-ND4, DAO, SDHB, SDHA, HIBADH, DCXR, NOX5, SCD, SELENOF, TXNDC12, GLUD1, LDHB, ACADM, AKR1B1, PAM, HAAO, KCNAB1, LBR, PTGR1, P3H3, DOHH, KDM5B, PAH, ADH4, ADH5, MTHFD2, BCKDHB, GLDC, UQCRFS1, CYP2J2, FXN, ASPHD2, IDO2, DNAJC10, CYB561D1, SCCPDH, GFOD1, NOX1, PIR, PDHA1, MDH2, SESN3, CYP4A11, CYP4F3, DHRS2, ETFDH, HADH, TXNRD1, ACAD11, MSRB3, GMPR2, GRHPR, PCYOX1, MSRA, DHRS7, MGST3, AOC2, DHRS3, RRM2, MDH1, ALDH9A1, SORD, OGDH, NDUFAF5, CYP20A1, D2HGDH, MGST2, SRD5A3, AGPS, KDM6B, AKR7A2, CYBB, IFI30, COX7A2, SNCA, GLUD2, DHRS7B, CYP2R1, AGMO, RIOX2, KIAA1191, ACAD9, KDM4A, CBR3, AKR1A1, IVD, HSD17B7, NSDHL, TP |
| oxidoreductase activity, acting on a sulfur group of donors | molecular function | IFI30, SRXN1 |
| oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor | molecular function | TXNDC8, TXNDC2, DNAJC10, MSRB3, ERO1A, MSRB2, ERO1B |
| oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor | molecular function | GSR, TXNRD1, TXNRD2 |
| oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | molecular function | PCYOX1 |
| oxidoreductase activity, acting on CH-OH group of donors | molecular function | XDH, DCXR, H6PD |
| oxidoreductase activity, acting on diphenols and related substances as donors | molecular function | CYP1A1 |
| oxidoreductase activity, acting on NAD(P)H | molecular function | DECR1, NDUFS4, NDUFS2, WDR93, NDUFS1, AIFM1, NDOR1, NDUFS8, RNLS, MT-ND4L |
| oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor | molecular function | CYB5R4 |
| oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular function | AKR1C3, DCXR, AKR1C2, CBR1, NDUFS7, AKR1C1, AKR1C4 |
| oxidoreductase activity, acting on other nitrogenous compounds as donors | molecular function | NQO2 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | molecular function | CYP1A1, CYP19A1, PLOD1, CYP24A1, CYP17A1, CYP1A2, CYP2B6, CYP11A1, CYP11B1, CYP21A2, CYP11B2, CYP1B1, CYP26B1, P3H3, CYP2J2, CYP4A11, CYP4F3, CYP20A1, CYP2R1, CYP2A7, CYP2C8, PLOD2, CYP4F8, CYP26A1, CYP4B1, CYP2A6, CYP2C19, CYP4F22, P4HA3, CYP8B1, P4HA1, CYP27B1, PTGIS, OGFOD3, CYP3A5, CYP2C18, EGLN1, CYP4F12, CYP51A1, PLOD3, EGLN2, P3H1, CYP2E1, TBXAS1, CYP4F2, CYP4Z1, CYP4X1, OGFOD1, P4HA2, CYP26C1, CYP46A1, CYP2D6, CYP2S1, CYP2D7, OGFOD2, CYP2W1, CYP4F11, CYP2C9, CYP3A43 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | molecular function | KDM5C, KDM5D, HSPBAP1, RIOX1, PHF8, EGLN1, HIF1AN, ALKBH3, ALKBH4, EGLN2, TYW5, ALKBH8, ALKBH1, PHYHD1, KDM8, OGFOD1, JMJD4, ALKBH5 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | molecular function | CYP11A1, CYP11B1, CYP11B2, POR, CYP26A1, MICAL3, NDOR1, MICAL2, CYP2E1, CYP4F2, MICAL1, COQ7, CYP4F11, COQ6 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen | molecular function | PAM, NLRP11, MOXD1, DBH |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | molecular function | CYP1A1, CYP19A1, CYP1A2, CYP2B6, CYP1B1, CYP2J2, CYP2R1, CYP2A7, CYP2C8, CYP2A6, CYP2C19, CYP3A5, CYP2C18, CYP2E1, CYP2D6, CYP2S1, CYP2D7, CYP2W1, COQ6, CYP2C9, CYP3A43 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | molecular function | PAH, TPH1, TPH2, TH |
| oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water | molecular function | SCD, SCD5 |
| oxidoreductase activity, acting on peroxide as acceptor | molecular function | PARK7, CAT, SESN3, SESN2 |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | molecular function | HPD |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | molecular function | PTGS2, ADO, BCO2, P4HA3, P4HA1, CDO1, ALOX5, ALOXE3, TMLHE, ALOX15B, P4HA2, ALOX12B, BCO1, RPE65 |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors | molecular function | XDH |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | molecular function | PDHA1, OGDH, OGDHL, DHTKD1, BCKDHA |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | molecular function | GAPDH, GAPDHS, ALDH1A2, ADH4, ALDH9A1, ALDH3A2, ALDH1A3, ALDH18A1, ALDH6A1, ALDH2, ALDH1L1, ALDH5A1, ALDH1A1, ALDH3B1, ALDH4A1, ALDH8A1, ALDH16A1, ALDH1L2 |
| oxidoreductase activity, acting on the CH-CH group of donors | molecular function | SRD5A2, SRD5A1, SDHA, ACADM, LBR, ACAD11, SRD5A3, ACAD9, IVD, ACAD10, ACOX3, GCDH, ACADVL, TECRL, TECR, ACADL, ACADSB, DHODH, SDHC, TM7SF2, DPYD, ACAD8, DHCR7, ACADS, ACOX2, ACOX1, ACOXL |
| oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | molecular function | LBR, SRD5A3, DHCR24, BDH2, TM7SF2, DHCR7 |
| oxidoreductase activity, acting on the CH-NH group of donors | molecular function | PRODH2 |
| oxidoreductase activity, acting on the CH-NH2 group of donors | molecular function | PNPO |
| oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | molecular function | GLUD1, GLUD2 |
| oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor | molecular function | LOXL2, LOX, LOXL3 |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | molecular function | HSD17B4, HSD3B1, HSD3B2, IDH1, LDHC, LDHA, LDHB, MDH2, GRHPR, DHRS3, MDH1, NSDHL, UGDH, CBR4, GLYR1, HSD17B8, HMGCR, CTBP2, PRXL2B, HPGD, HSD3B7, IDH3B, BDH2, IDH2, GPD1L, IDH3G, CTBP1, MDH1B, PHGDH, LDHAL6B, HSD17B11, IDH3A, RDH10, RDH11 |
| oxidoreductase activity, oxidizing metal ions with flavin as acceptor | molecular function | ETFDH |
| oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor | molecular function | MTRR |
| oxoglutarate dehydrogenase (succinyl-transferring) activity | molecular function | OGDH, OGDHL, DHTKD1 |
| oxoglutarate:malate antiporter activity | molecular function | SLC25A11 |
| oxygen binding | molecular function | CYP1A1, CYP19A1, CYP17A1, CYP1A2, CYP2B6, ALB, CBS, CYP1B1, HBG2, CYP2A7, CYP26A1, CYP4B1, HBD, CYP2C19, HBB, CYP8B1, HBZ, CYP3A5, CYP2C18, ADGB, MB, TH, HBQ1, CYP2E1, NGB, HBA1, CYGB |
| oxygen carrier activity | molecular function | IPCEF1, HBG2, HBD, HBB, HBZ, MB, HBQ1, NGB, HBA1, CYGB |
| oxygen sensor activity | molecular function | HIF1AN, EGLN2 |
| oxygen-dependent protoporphyrinogen oxidase activity | molecular function | PPOX |
| oxysterol binding | molecular function | GPR183, OSBPL5, RORA, OSBP, RORC |
| oxytocin receptor activity | molecular function | OXTR |
| oxytocin receptor binding | molecular function | OXT |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity | molecular function | SEC61G, TOMM20, TIMM17B, TIMM17A |
| P-TEFb complex binding | molecular function | TAF7 |
| P2Y1 nucleotide receptor binding | molecular function | DLG4 |
| p53 binding | molecular function | TP53, GSK3B, MDM2, CDKN2A, MUC1, HSPD1, BRD4, TP63, TEP1, RNF20, RNF34, TRIM24, ZNF385B, BCL2L12, ZNF385A, SMARCA4, PTTG1IP, TP53BP2, MAPKAPK5, CREBBP, EHMT2, EEF2, RFWD3, MSX1, TAF3, SMARCB1, EHMT1, TRIAP1, TAF1, EP300, SETD7, USP7, RCHY1, TP53BP1, BLM, PPP1R13B, HTT, POU4F2, BANP, CDKN2AIP, CDK5, TRIM29, USP10, PLK3, TP53RK, RNF125, CHD8, DUSP26, ANKRD1, TAF9, SMYD2, NUAK1, GATA1, KMT5A |
| palmitoleoyltransferase activity | molecular function | CPT1A |
| palmitoleyl hydrolase activity | molecular function | NOTUM |
| palmitoyl hydrolase activity | molecular function | PPT1 |
| palmitoyl-(protein) hydrolase activity | molecular function | PPT1, LYPLAL1, ABHD12, LYPLA1, ABHD17B, ABHD17A |
| palmitoyl-CoA 9-desaturase activity | molecular function | SCD |
| palmitoyl-CoA hydrolase activity | molecular function | PPT1, GNPAT, ACAA2, BAAT, THEM5, THEM4, ACOT7, ACOT2, ACOT11, ACOT4 |
| palmitoyl-CoA oxidase activity | molecular function | ACAA1, ACADL, ACOX1 |
| palmitoyl-[acyl-carrier-protein] hydrolase activity | molecular function | OLAH, FASN |
| palmitoyltransferase activity | molecular function | ZDHHC16, ZDHHC8, ZDHHC5, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC23, HHAT, ZDHHC19, ZDHHC21, ZDHHC11, ZDHHC20, ZDHHC3, ZDHHC2, ZDHHC13, ZDHHC7, ZDHHC24, ZDHHC4, ZDHHC22, ZDHHC12, ZDHHC18, ZDHHC1 |
| pancreatic polypeptide receptor activity | molecular function | NPY1R, NPY5R |
| pantetheine hydrolase activity | molecular function | VNN2, VNN1, VNN3 |
| pantetheine-phosphate adenylyltransferase activity | molecular function | COASY |
| pantothenate kinase activity | molecular function | PANK2, PANK4, PANK1 |
| pantothenate transmembrane transporter activity | molecular function | SLC5A6 |
| parathyroid hormone receptor activity | molecular function | PTH1R, PTH2R |
| passive transmembrane transporter activity | molecular function | SLC5A8 |
| patched binding | molecular function | CCNB1, SHH, SMO, DHH, PTCH1, IHH, BBS1, CAV1 |
| pattern recognition receptor activity | molecular function | COLEC12, NOD2, MARCO, DMBT1, FCN1, TLR9, TLR7, NOD1, TRIM5 |
| PDZ domain binding | molecular function | CFTR, PTEN, TGFBR3, NCOA2, GJA1, SLC22A5, BAIAP2, CIT, FZD8, FZD4, RAPGEF2, NSF, LIN7C, SLC9A3R1, GIPC1, KIF14, SLC22A12, PLEKHA1, PRKN, SDC2, SNTG2, SYNJ2, FZD2, CACNG3, FZD3, DTNA, LNX1, FZD7, PSEN1, ERC1, KIDINS220, MAP2K2, CRIPT, CLCN3, CXADR, GRIK5, ARHGAP29, PLEKHA2, CCDC88C, F11R, ATP2B3, EXOC4, GNG5, ACVR2A, KCNJ4, DLG4, LPAR1, LLGL2, DLG3, GNG12, ADGRB1, GRID2, SNTB1, SLC22A4, ADRB1, ATP2B1, MUC17, SNTA1, SRR, GRIA1, ATP2B2, ARHGEF16, SLC34A1, SLC26A6, FZD1, GRIK2, GRM7, ACOX1, SHISA6, DOCK4, LIN7B, NKD1 |
| pentose transmembrane transporter activity | molecular function | SLC5A1 |
| peptidase activator activity | molecular function | APP, FN1, CLPX, FBLN1, PINK1, CFLAR, PCOLCE2, PCOLCE, CAV1 |
| peptidase activator activity involved in apoptotic process | molecular function | CTSC, EBAG9, MAL, CASP8AP2, CTSH |
| peptidase activity | molecular function | USP9Y, F10, MMP2, ACE, MMP9, CASP1, CASP4, CASP6, USP1, CASP3, CASP9, CASP8, USP26, KLK3, CTSD, CLCA4, ASRGL1, PARK7, ADAMTS1, ADAMTS5, LTF, ACR, MMP12, PLAU, PLAT, MMP7, ADAMTS20, SHH, DPP8, ELANE, PSMA3, USP8, CPN1, ACE2, MALT1, PMPCB, LTA4H, PSMB1, PSMB5, SEC11A, LACTB, AGBL2, AGBL4, USP38, PSMA8, COPS5, USP47, PARL, SENP2, ERAP1, PSMA7, CPM, PSMA1, PSMA2, PSMA5, PSMB2, METAP2, ERAP2, SPPL2A, USP13, PSMB7, SEC11C, CPVL, UFSP2, EIF3F, CTSK, USP14, CTSW, BLMH, MINDY4, ERMP1, AOPEP, HMCES, SENP6, KLK9, USP16, ATP23, USP3, PSMD14, CFD, SPCS3, ESPL1, CPZ, MINDY1, APH1B, MINDY3, FOLH1B, CPQ, SPCS1, CTSV, ZMPSTE24, PROC, CTSL, CTSB, ECE2, EEF1AKMT4-ECE2, PGC, TPSB2, PSMB6, ECE1, SPCS2, TPSAB1, CLPP, USP32, OMA1, STAMBPL1, SENP5, DPEP3, DPP3, LAP3, CTSC, NPEPPS, AMZ2, LONP2, ATG4A, IMMP1L, USP28, DESI2, RNPEP, USP29, RHBDL2, HTRA2, F7, GZMB, PSMB4, MBTPS1, MMEL1, LGMN, TPSG1, CELA3B, C1S, IDE, CAPN3, PSMB8, CTRL, USP30, USP51, USP37, CPXM1, ADAMTS9, TLL2, PRCP, MMP15, PSMA6, TMPRSS11B, TMPRSS12, OTUD7A, ADAMTS18, |
| peptidase inhibitor activity | molecular function | SERPINC1, TIMP1, ANOS1, BIRC5, SERPINE1, TFPI2, SERPINA1, APP, A2M, SERPINA5, EPPIN, NGF, SPINK1, SERPINA3, SLPI, TIMP2, XIAP, SERPINB7, TFPI, WFDC10A, SPINK5, ITIH2, SERPINB6, WFDC8, CSTB, CST2, PEBP1, SPINT2, TIMP3, SERPINB2, SERPINB9, COL7A1, PI16, WFDC13, BIRC7, CST11, WFDC1, SPINT1, CST5, APLP2, SERPINF2, SERPINB1, NAIP, SERPINA4, PI15, SPINK6, CSTA, CAST, SERPINB3, SPINT3, CARD18, BIRC6, PI3, CARD16, WFIKKN2, SERPINI1, WFDC2, TIMP4, R3HDML, SERPINB8, CST6, ITIH6, CD109, WFIKKN1, CST7, SERPING1, RENBP, LXN, SERPINA10, CST4, COL6A3, GPC3, ITIH4, WFDC3, WFDC12, AMBP, UMODL1, ITIH5, SERPINA9, SERPINA12, A2ML1, COL28A1, WFDC5, HMSD, PAPLN, RECK, ITIH3, FETUB |
| peptide alpha-N-acetyltransferase activity | molecular function | NAA20, NAA25, NAA35, NAA16, NAA50, NAA30, NAA15, NAA80, NAA10, NAA60 |
| peptide antigen binding | molecular function | HLA-DRB1, HLA-DPB1, HLA-B, HLA-DQB1, HLA-A, HLA-E, HLA-DRA, HFE, HLA-DQA1, HLA-G, SLC7A5, AZGP1, HLA-C, TAP1, DHCR24, CD209, SLC7A8, SLC7A9, TAPBP, HLA-DPA1, FCGRT, MAML1, HLA-F |
| peptide binding | molecular function | PLOD1, ITGB1, GNRHR, OXTR, TUBB3, MAS1, ERAP1, ERAP2, RPS6KB2, GPR37L1, CTSV, NPEPPS, IDE, CCKAR, ADNP, HCRTR1, THOP1, RELA, CRHBP, PGGT1B, NPR3, MCHR1, NPFFR2, PPIF, CRIP1, TMEM158, NLN, TPP1, CLTA, OPRD1, NPBWR1, NUP98, LNPEP, PROKR1, PTGDR2, AVPR2, AVPR1B, LVRN, GPR150, MME, CLTB, SSTR4, SSTR3, ENPEP, TRHDE, ANG, FURIN, ANPEP, OPRL1, CALR, SSTR5, NPBWR2, GPR1, OPRK1, BDKRB1 |
| peptide butyryltransferase activity | molecular function | EP300 |
| peptide deformylase activity | molecular function | PDF |
| peptide disulfide oxidoreductase activity | molecular function | TXNDC12, P4HB, PDIA6, PDIA4, PDIA5, PDIA2 |
| peptide hormone binding | molecular function | INHBA, RXFP2, PRLR, OXTR, MAS1, ANXA5, ECE1, PTH1R, ACVR1, IDE, CCKAR, GHSR, HCRTR1, GIPR, GUCY2F, GHRHR, NPR3, GCGR, EDNRB, GLP1R, GHR, CRHR1, CRHR2, SLC40A1, NPR1, PTH2R, GLP2R, GUCY2D, ADCYAP1R1, GALR1, SCTR, NPR2, GALR3, VIPR2, MC3R |
| peptide hormone receptor binding | molecular function | LEP, PTPN11, JAK2, PTHLH, CCK |
| peptide receptor activity | molecular function | GUCY2F, NPR1, GUCY2D, NPR2 |
| peptide transmembrane transporter activity | molecular function | SLC15A4, TAP1, SLC15A2, TAP2, SLC15A1 |
| peptide YY receptor activity | molecular function | NPY1R, NPY5R |
| peptide-aspartate beta-dioxygenase activity | molecular function | ASPH |
| peptide-glutamate-N-acetyltransferase activity | molecular function | NAA10 |
| peptide-lysine-N-acetyltransferase activity | molecular function | CREBBP, EP300, KAT5, ESCO1, KAT2A, KAT2B |
| peptide-methionine (R)-S-oxide reductase activity | molecular function | MSRB3, MSRB2, MSRB1, TXN2 |
| peptide-methionine (S)-S-oxide reductase activity | molecular function | MSRA, TXN2 |
| peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity | molecular function | NGLY1 |
| peptide-O-fucosyltransferase activity | molecular function | POFUT2, POFUT1 |
| peptide-serine-N-acetyltransferase activity | molecular function | NAA40, NAA10 |
| peptide:proton symporter activity | molecular function | SLC15A4, SLC15A2, SLC15A1 |
| peptidoglycan binding | molecular function | TLR2, REG3A, REG1B, NOD2, REG3G, PGLYRP4, NLRP3, PGLYRP2, TREM2, NOD1, RNASE7 |
| peptidoglycan glycosyltransferase activity | molecular function | CSGALNACT1 |
| peptidoglycan immune receptor activity | molecular function | PGLYRP4, PGLYRP2 |
| peptidyl-asparagine 3-dioxygenase activity | molecular function | HIF1AN |
| peptidyl-aspartic acid 3-dioxygenase activity | molecular function | ASPH |
| peptidyl-cysteine S-nitrosylase activity | molecular function | GAPDH |
| peptidyl-dipeptidase activity | molecular function | ACE, ACE2 |
| peptidyl-dipeptidase inhibitor activity | molecular function | GPC3 |
| peptidyl-histidine dioxygenase activity | molecular function | HIF1AN |
| peptidyl-lysine acetyltransferase activity | molecular function | NAA50 |
| peptidyl-proline 3-dioxygenase activity | molecular function | OGFOD1 |
| peptidyl-proline 4-dioxygenase activity | molecular function | EGLN1, EGLN2 |
| peptidyl-proline dioxygenase activity | molecular function | EGLN1, EGLN2, OGFOD1 |
| peptidyl-prolyl cis-trans isomerase activity | molecular function | FKBP4, FKBPL, FKBP6, FKBP5, CWC27, PPIL6, PPIL4, PPIL3, PPIB, FKBP14, PIN1, AIP, FKBP7, FKBP10, FKBP3, NKTR, PPID, PPIF, PPIG, FKBP1B, FKBP11, PIN4, RANBP2, PPWD1, PPIH, FKBP2, PPIE, FKBP8, AIPL1, PPIL2, PPIA, PPIC |
| peptidylamidoglycolate lyase activity | molecular function | PAM |
| peptidylglycine monooxygenase activity | molecular function | PAM |
| peptidyltransferase activity | molecular function | GGT7, GGT1 |
| peroxidase activity | molecular function | PTGS1, PTGS2, GPX1, GPX4, PRDX4, CAT, LPO, PRDX2, PRDX1, IPCEF1, TPO, HBG2, PXDNL, GSTA1, PRDX6, EPX, GPX3, HBD, HBB, HBZ, PRDX3, GPX2, PRDX5, DUOX2, MPO, HBQ1, TXNDC17, PXDN, GPX7, HBA1, DUOX1, CYGB |
| peroxidase inhibitor activity | molecular function | LRRK2 |
| peroxiredoxin activity | molecular function | PRDX4, PARK7, PRDX2, PRDX1, PRDX6, PRDX3, PRDX5 |
| peroxisome matrix targeting signal-1 binding | molecular function | PEX5, PEX5L |
| peroxisome matrix targeting signal-2 binding | molecular function | PEX7 |
| peroxisome membrane class-1 targeting sequence binding | molecular function | PEX19 |
| peroxisome membrane targeting sequence binding | molecular function | PEX19, PEX5 |
| peroxisome proliferator activated receptor binding | molecular function | ESR2, MDM2, ASXL2, ASXL1, TACC1, PPARGC1A, PRMT2, IKBKG, NFATC4, ASXL3 |
| peroxisome targeting sequence binding | molecular function | PEX5, BABAM2, PEX5L |
| peroxynitrite isomerase activity | molecular function | THAP4 |
| peroxynitrite reductase activity | molecular function | PRDX5 |
| PH domain binding | molecular function | INPP5A, EPHA4, LSM4, EPB41L2 |
| pH-gated chloride channel activity | molecular function | PACC1 |
| phenanthrene 9,10-monooxygenase activity | molecular function | AKR1C3, AKR1C2, AKR1C1 |
| phenanthrene-9,10-epoxide hydrolase activity | molecular function | AKR7A2 |
| phenethylamine:oxygen oxidoreductase (deaminating) activity | molecular function | AOC2, AOC3 |
| phenylalanine 4-monooxygenase activity | molecular function | PAH, PCBD1 |
| phenylalanine-tRNA ligase activity | molecular function | FARS2, LRRC47, FARSB, FARSA |
| phenylpyruvate tautomerase activity | molecular function | MIF |
| pheromone receptor activity | molecular function | VN1R2, VN1R3 |
| phosphatase activator activity | molecular function | GTF2F1, FRS2, BMP2 |
| phosphatase activity | molecular function | PTEN, ACP1, EPHX2, PTPN11, DUSP6, ACPP, PTPRJ, PTPDC1, ALPP, CDKN3, RNGTT, MTM1, DUSP13, PXYLP1, DUSP11, ALPI, PTPRR, MDP1, DUSP22, DUSP8, DUSP19, NT5C3B, DUSP15, PLPP2, PTPRF, MTMR4, PTPRA, PLPPR2, PTPN23, PTPN2, HDHD2, PLPP1, PTPN6, FBP1, PPP1CB, NT5C, PTP4A1, LHPP, DUSP21, PTPRG, DUSP27, PTPRT, DUSP14, PSPH, PTPN20, PTPN22, PTPRC, DUSP5, MINPP1, PTPN13, SSH2, PLPP5, PHOSPHO1, SACM1L, PTPRB, PTPN9, ATP1A2, CTDSP2, CDC14B, PTPRM, PHOSPHO2, PTPMT1, PTPRN2, ARMT1, CTDSPL2, MTMR1, DUSP18, PGP, DUSP28, SSH3, PTPRU, PTPN1, PTPRE, CTDSPL, DUSP1, PPP5C, PUDP, CTDSP1, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, PLPPR4, FBP2, PTPN5, SSH1, PLPP3, ATP1A1, CA3, PTPRS, PTPN14, PRUNE1, PLPPR1, PGAM5, CTDNEP1, PTPRZ1, PTPN12, PTPN18, PTPRH, PTPN4, DUSP9, DUSP16, ALPL, DUPD1, PDXP, PLPPR3, DUSP26, PTPRD, PTPN3, PLPP4, DUSP2, MTMR7, DUSP10 |
| phosphatase binding | molecular function | MAPK3, MAPK1, MAST2, TERF2IP, CNST, TRPC4AP, PPP1R36, SIGLEC11, SLC9A3R1, CTSC, ELL, DZIP3, PPP1R35, CSRNP2, SYK, SPRED1, WNK1, NFATC2, PPP1R32, SBF2, DLG1, SYTL2, RCAN3, CARHSP1, CRY1, SH3RF2, SH3YL1, CHCHD3, SMAD2, TPRN, DLG3, SFI1, PPP3R1, SLC9A3R2, TSC2, PPP1R27, PPARA, CRY2, SH3GL1, SPTBN4, SMAD3, CEP192, MAGI2, SIGLEC10 |
| phosphatase inhibitor activity | molecular function | ARPP19, URI1, ANP32E, TESC |
| phosphatase regulator activity | molecular function | ZEB2, SBF1, PPP1R12A, BMP2K, SBF2, MTMR12, PPP1R12B, PPP1R12C |
| phosphate ion binding | molecular function | MTHFD2, ADSS2, PNP, RELA, ADSS1, GNG12, RPH3A, CHST14, PDE2A |
| phosphate ion transmembrane transporter activity | molecular function | SLC17A1, ANKH, XPR1 |
| phosphate:proton symporter activity | molecular function | SLC25A3 |
| phosphatidate cytidylyltransferase activity | molecular function | TAMM41, CDS1 |
| phosphatidate phosphatase activity | molecular function | PLPP2, PLPPR2, PLPP1, LPIN1, PLPP5, LPIN2, PLPPR4, PLPP3, PLPPR1, PLPPR3, LPIN3, PLPP4 |
| phosphatidic acid binding | molecular function | RAPGEF2, SESTD1, RAPGEF6, ATP13A2, OPA1, PACSIN2, MAPKAP1, JPH2, PITPNC1, COMMD1, PITPNM1, GRAMD1B, NRGN, GSDMD, MICALL1, PLEKHN1, MARK1 |
| phosphatidyl phospholipase B activity | molecular function | PNPLA8, LIPC, PLA2G4A, PNPLA6, PLA2G15, PNPLA7, ASPG, PLB1 |
| phosphatidyl-N-dimethylethanolamine N-methyltransferase activity | molecular function | PEMT |
| phosphatidyl-N-methylethanolamine N-methyltransferase activity | molecular function | PEMT |
| phosphatidylcholine binding | molecular function | SERPINA5, PITPNB, CHMP2A, PITPNA, SESTD1, SCARB2, GPR119, RASGRP1, PCTP, PCYT1B, APOA1, ANXA13, ESYT2, APOC1, PITPNM1, APOA5, ESYT1, PITPNM2, ESYT3, CETP, GPR12, NF1, PCYT1A, CHMP3, RPE65 |
| phosphatidylcholine floppase activity | molecular function | ABCG1, ABCB4, ABCA7 |
| phosphatidylcholine transfer activity | molecular function | SCP2 |
| phosphatidylcholine transporter activity | molecular function | PITPNB, PITPNA, PCTP, PITPNC1, PITPNM1, PITPNM2 |
| phosphatidylcholine-sterol O-acyltransferase activator activity | molecular function | APOE, APOA1, APOC1, APOA5 |
| phosphatidylcholine-sterol O-acyltransferase activity | molecular function | LCAT |
| phosphatidylethanolamine binding | molecular function | MAP1LC3A, PEBP1, PEMT, MFGE8, ANXA11, ESYT2, ESYT1, ESYT3, NF1 |
| phosphatidylethanolamine flippase activity | molecular function | ABCA4 |
| phosphatidylethanolamine N-methyltransferase activity | molecular function | PEMT |
| phosphatidylglycerol binding | molecular function | PITPNA, PITPNC1, ANXA13 |
| phosphatidylglycerophosphatase activity | molecular function | PTPMT1 |
| phosphatidylinositol 3-kinase activity | molecular function | PIK3CA, PIK3C2A, PIK3C3, PIK3CG, PIK3CD |
| phosphatidylinositol 3-kinase binding | molecular function | INSR, IGF1R, JAK2, PIK3R1, DAB2IP, RASD2, IRS2, IRS1, CALM3, BECN1, IRS4, PDGFRB, ATP1A1, LCK, CORO1A, INSRR, TYRO3 |
| phosphatidylinositol 3-kinase catalytic subunit binding | molecular function | FAM83B, PIK3IP1 |
| phosphatidylinositol 3-kinase regulator activity | molecular function | KLF4, PIK3R1, WDR91, WDR81, AGAP2 |
| phosphatidylinositol 3-kinase regulatory subunit binding | molecular function | ESR1, PIK3R1, DAB2IP, FAM83B, PIK3AP1, PTPN13, CBL, FBXL2, FAM83A |
| phosphatidylinositol binding | molecular function | 41153, SNX3, PITPNB, SNX16, MTM1, ZCCHC14, SNX19, PIK3C2A, SNX7, SNX6, ARHGAP32, SNX2, TULP3, SNX27, PITPNA, PLD1, PASK, SNX14, SNX10, SNX4, ARHGAP33, CCDC88A, HS1BP3, SNX20, SNX32, NOXO1, ING2, SNX8, PARD3B, SNX21, RPS6KC1, SNX30, SNX33, KIF16B, SNX5, ITPR3, AIDA, SNX24, GRB7, SNX29, PARD3, MITD1, SNX9, PXK, SBF2, PITPNC1, NCF1, SNX13, ESYT2, FCHO2, NUMA1, SGK3, GRAMD2A, EXOC8, SH3YL1, SNX12, PITPNM1, ITPR1, ZCCHC2, APPL2, SNX15, PIK3C2B, MCF2L, ITPR2, PLD2, NCF4, ESYT1, PITPNM2, NISCH, C2CD2L, PXDC1, SNX18, PHF12, APPL1, ESYT3, SNX22, TLN1, SH3PXD2B, FES, HIP1R, SNX17, SH3PXD2A, PLEKHF1, TNFAIP8L3, SNX25, PLEKHF2, RAG2, TRPV1 |
| phosphatidylinositol bisphosphate binding | molecular function | LAPTM4B, ADAP2, TTPA, ADAP1, CLVS1, RLBP1, TTPAL |
| phosphatidylinositol deacylase activity | molecular function | PGAP1 |
| phosphatidylinositol kinase activity | molecular function | PIK3C2A, PIK3C3, PIK3CG, PIK3C2B, PIK3CD, PI4KB, PI4KA |
| phosphatidylinositol N-acetylglucosaminyltransferase activity | molecular function | PIGA, PIGH, PIGP, PIGQ, PIGY |
| phosphatidylinositol phosphate 4-phosphatase activity | molecular function | INPP5F, SACM1L |
| phosphatidylinositol phosphate 5-phosphatase activity | molecular function | SYNJ1, INPP5F, SYNJ2, INPP5K |
| phosphatidylinositol phosphate binding | molecular function | SNX3, RNF34, ARHGAP32, PHLDA2, DENND1C, DENND1A, ANKFY1, WDR45, DENND1B, RUBCNL, RUBCN, FGD2, RPH3A, PLEKHN1, PHLDA3, GAP43, PHLDA1 |
| phosphatidylinositol phosphate kinase activity | molecular function | PIKFYVE, PIP5K1A, PIP4K2A, PIP5K1B, PIP4K2C, PIP4K2B, PIP5K1C |
| phosphatidylinositol phosphate phosphatase activity | molecular function | MTMR6, MTMR1, MTMR7 |
| phosphatidylinositol phospholipase C activity | molecular function | EDNRA, CCL5, CCR5, PLCZ1, PLCH2, CCR1, BDKRB2, PLCL1, PLCB2, PLCB3, PLCD1, CHRM3, PLCE1, GDPD5, F2RL2, CHRM1, CHRM5, PLCD4, PLCG2, PLCH1, PLCL2 |
| phosphatidylinositol transfer activity | molecular function | PITPNB, SCP2, PITPNA, OSBPL2, PITPNC1, PITPNM1, PITPNM2, C2CD2L, TNFAIP8L3 |
| phosphatidylinositol trisphosphate phosphatase activity | molecular function | INPP5K |
| phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity | molecular function | PTEN, TPTE, INPP5E, INPP5D, TPTE2 |
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity | molecular function | INPP5K |
| phosphatidylinositol-3,4,5-trisphosphate binding | molecular function | AKT1, FERMT2, OGT, IQGAP1, IQGAP2, ARAP1, CYTH3, DAPP1, FCHSD2, ARHGAP9, ZFYVE16, ADAP2, ARAP2, ZFYVE1, KIF16B, ARAP3, PARD3, GAB2, MAPKAP1, JPH2, COMMD1, PLEKHB2, MYO1B, OBSCN, ADAP1, MYO10, BTK, GBF1, NRGN, MYO1G, HIP1R, WASHC2C, PHLDA3, ANXA8, RAG2, ASAP1 |
| phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity | molecular function | PTEN |
| phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity | molecular function | INPP4B, INPP4A |
| phosphatidylinositol-3,4-bisphosphate 5-kinase activity | molecular function | PIK3CG, PIK3CD, IPMK |
| phosphatidylinositol-3,4-bisphosphate binding | molecular function | AKT1, DAPP1, SESTD1, FCHSD2, PLEKHA1, PLEK, ADAP2, PLEK2, ZFYVE1, KIF16B, ARAP3, PLEKHA4, GAB2, MAPKAP1, NCF1, TTPA, COMMD1, OBSCN, PLEKHA2, MYO1G, HIP1R, SH3PXD2A, WASHC2C, PHLDA3, ANXA8, RAG2 |
| phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | molecular function | MTM1, MTMR6, MTMR4, MTMR8, MTMR1, MTMR3 |
| phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity | molecular function | PIKFYVE |
| phosphatidylinositol-3,5-bisphosphate binding | molecular function | SNX3, ACAP2, SESTD1, SNX14, ATP13A2, PLEK2, KIF16B, SNX5, PLEKHA4, WDR45, MAPKAP1, JPH2, COMMD1, WIPI2, WDR45B, WIPI1, CLVS1, GBF1, PLEKHA5, SH3PXD2B, HIP1R, TPCN1, WASHC2C, PHLDA3, RAG2 |
| phosphatidylinositol-3,5-bisphosphate phosphatase activity | molecular function | MTMR6, MTMR8 |
| phosphatidylinositol-3-phosphatase activity | molecular function | PTEN, SYNJ1, MTM1, MTMR6, MTMR4, MTMR8, MTMR11, MTMR9, SACM1L, MTMR12, MTMR1, MTMR3, MTMR14, MTMR7 |
| phosphatidylinositol-3-phosphate binding | molecular function | SNX3, SNX19, BBS5, SNX27, DAB2IP, SESTD1, VPS36, DENND1A, SNX20, NOXO1, SAP30L, LANCL2, PLEK2, SNX21, ZFYVE1, KIF16B, RUFY4, PLEKHA4, SNX24, PARD3, WDR45, JPH2, NCF1, WIPI2, WDR45B, SNX13, OBSCN, RUBCNL, PLA2G4A, SNX12, WIPI1, ZFYVE26, NCF4, PLEKHA5, SH3PXD2B, TECPR1, SH3PXD2A, PLEKHF1, ZFYVE28, WASHC2C, PHLDA3 |
| phosphatidylinositol-4,5-bisphosphate 3-kinase activity | molecular function | EGFR, EGF, KITLG, ERBB2, FGFR2, FGFR3, FGFR1, KIT, PIK3CA, NRG1, FGF17, FGF8, PTPN11, FGF3, FGF9, PIK3CG, PIK3CD, PIK3R6, IPMK |
| phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity | molecular function | INPP4B, INPP4A, PIP4P1, PIP4P2 |
| phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | molecular function | SYNJ1, OCRL, SYNJ2, PTPMT1, INPP5K, INPP5B, INPP5E, INPP5D |
| phosphatidylinositol-4,5-bisphosphate binding | molecular function | TWF1, ANXA2, MTSS2, SCIN, GSDME, TULP3, SESTD1, TULP1, PFN2, SNX20, AMER3, STXBP6, ADAP2, SLC9A1, SYT1, PICALM, RAB35, SNX21, SYT5, SNAP91, ANXA9, OSBPL2, ACTN2, PLCD1, TIRAP, GSDMB, PLEKHA4, FZD7, PARD3, SDCBP2, MAPKAP1, JPH2, TTPA, COMMD1, SDCBP, KRIT1, MYO1B, FCHO2, OBSCN, SYTL2, GRAMD2A, EXOC1, CAPG, CGAS, KCNJ2, AMER1, AMER2, TWF2, RPH3A, AVIL, SNX18, SYT9, MYO1G, SYT7, HIP1R, GSDMD, FRMPD4, SH3PXD2A, KCNJ1, SYT10, MARK1, VIL1, GSDMA, GSDMC, WASHC2C, PHLDA3, ANXA8, RAG2, ASAP1 |
| phosphatidylinositol-4,5-bisphosphate phosphatase activity | molecular function | INPP5E |
| phosphatidylinositol-4-phosphate binding | molecular function | SNX3, DAB2IP, SESTD1, PLEKHA3, OSBPL5, SAP30L, LANCL2, OSBPL8, SNX5, GSDMB, SNX24, JPH2, CERT1, GOLPH3L, GOLPH3, OBSCN, RUBCNL, PLA2G4A, ARFIP1, OSBP, PLEKHA8, PLEKHA5, SH3PXD2B, GSDMD, SH3PXD2A, PLEKHF1, GSDMA, GSDMC, WASHC2C |
| phosphatidylinositol-4-phosphate phosphatase activity | molecular function | SYNJ1, INPP5F, SACM1L |
| phosphatidylinositol-5-phosphate binding | molecular function | SNX3, SESTD1, SAP30L, LANCL2, SNX5, SNX24, JPH2, WIPI2, OBSCN, RUBCNL, PLA2G4A, VEPH1, PLEKHA5, SH3PXD2B, SH3PXD2A, PLEKHF1, WASHC2C, PHLDA3 |
| phosphatidylserine 1-acylhydrolase activity | molecular function | PLAAT1, LPL, PLAAT3, LIPG, PLAAT5, LIPC, PLA2G15, PLA1A |
| phosphatidylserine binding | molecular function | AXL, GAS6, HSPA8, SCIN, SYT13, SESTD1, SCARB2, SCARB1, OSBPL5, SYT1, MFGE8, SYT5, ANXA9, THBS1, OSBPL8, GSDMB, HMGB1, SYT12, JPH2, ANXA13, CPNE1, FCHO2, SYTL2, OSBPL10, APPL2, CD300LF, SYT17, ADGRB1, CPNE6, MME, SYT6, SYT9, APPL1, TLN1, GRAMD1B, TRIM72, SYT7, GSDMD, SYT2, SYT3, SYT15, PLEKHN1, SYT10, MARK1, RPE65, GSDMA, GSDMC, CAVIN2, GAP43, ASAP1 |
| phosphatidylserine decarboxylase activity | molecular function | GOT1, PISD |
| phosphatidylserine floppase activity | molecular function | ABCA7 |
| phosphatidylserine transfer activity | molecular function | OSBPL5, OSBPL8 |
| phospho-N-acetylmuramoyl-pentapeptide-transferase activity | molecular function | DPAGT1 |
| phosphoacetylglucosamine mutase activity | molecular function | PGM3 |
| phosphocholine phosphatase activity | molecular function | PHOSPHO1 |
| phosphodiesterase decapping endonuclease activity | molecular function | NUDT16, EDC3 |
| phosphodiesterase I activity | molecular function | APEX1, FAN1, ENPP2, APEX2, ENPP3, ENPP1 |
| phosphoenolpyruvate carboxykinase (GTP) activity | molecular function | PCK2 |
| phosphoenolpyruvate carboxykinase activity | molecular function | PCK2 |
| phosphoethanolamine phosphatase activity | molecular function | PHOSPHO1 |
| phosphoglucomutase activity | molecular function | PGM3, PGM1, PGM5, PGM2 |
| phosphogluconate dehydrogenase (decarboxylating) activity | molecular function | HIBADH, PGD |
| phosphoglycerate dehydrogenase activity | molecular function | PHGDH |
| phosphoglycerate kinase activity | molecular function | PGK2, PGK1 |
| phosphoglycerate mutase activity | molecular function | PGAM1, PGAM4, BPGM, PGAM2 |
| phosphoglycolate phosphatase activity | molecular function | APTX, PGP |
| phospholipase A1 activity | molecular function | PLAAT1, LPL, PLAAT3, PLA2G4C, LIPG, PLAAT5, LIPC, PLA2G15, PLA1A |
| phospholipase A2 activator activity | molecular function | CASP3, PLAA |
| phospholipase A2 activity | molecular function | PLA2G6, PAFAH1B2, PLA2G2A, PLA2G10, PLAAT1, PLAAT3, PLA2G4C, PRDX6, PLA2G3, PLAAT5, PROCA1, PNPLA3, PLA2G4A, PLA2G15, PLA2G1B, PGAP6, PLA2G12A, PLA2G5, PLA2G2D, PLB1, PLA2G12B |
| phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) | molecular function | PLA2G10, PLAAT1, PLAAT3, PLA2G4C, PRDX6, PLA2G3, PLAAT5, PLA2G4A, PLA2G15, PLA2G1B, PGAP6, PLA2G12A, PLA2G5, PLA2G2D, PLB1 |
| phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) | molecular function | PLA2G10, PLAAT1, PLAAT3, PLA2G4C, PRDX6, PLA2G3, PLAAT5, PLA2G4A, PLA2G15, PLA2G1B, PGAP6, PLA2G12A, PLA2G5, PLA2G2D, PLB1 |
| phospholipase A2 inhibitor activity | molecular function | ANXA2, ANXA3, ANXA1, ANXA9 |
| phospholipase activator activity | molecular function | CCL5, CCL8, CCL3, ARHGAP6, PDPK1, GM2A |
| phospholipase activity | molecular function | PNPLA8, PLA2G10, LPL, PLA2G4C, ABHD12, LYPLA1, LIPG, PITPNM3, PLBD2, ABHD16A, LIPC, NAPEPLD, DDHD2, DDHD1, ABHD16B, SMPD3, LIPH, PLA2G4A, ABHD6, PNLIPRP2, PLA1A, PLB1 |
| phospholipase binding | molecular function | PTPN11, PRKN, LMNB1, SRSF3, PLA2R1, ARHGAP6, PRKCZ, WAS, PDPK1, DGKQ, NEFL |
| phospholipase C activity | molecular function | PDIA3, PLCZ1, PLCH2, PLCL1, PLCB2, PLCB3, PLCE1, NOTUM, PLCD4, PLCG2 |
| phospholipase D activator activity | molecular function | ARF1 |
| phospholipase D activity | molecular function | HMOX1, PLD1, FAM83B, PLD4, GPLD1, PLD2, PLD3 |
| phospholipase inhibitor activity | molecular function | ANXA2, ANXA5, ANXA4, ANXA3, ANXA1, ANGPTL3, APOC1 |
| phospholipid binding | molecular function | NR5A2, F10, APOE, NR5A1, APOB, PON1, F3, BAD, ANXA5, PLA2G2A, GRK5, PAFAH2, OSBPL1A, MAP1LC3A, SHC1, CPS1, NUP35, EPN3, DAPP1, PLA2G4C, SNCA, ENTHD1, NUP62, RASA2, STAP1, ANXA1, SYTL4, ARHGAP35, SPTBN1, NOXO1, PSAP, SYT1, ABCG1, PICALM, ARL6, SNAP91, ANXA9, DGKA, CLINT1, PSD2, PACSIN2, FAM92A, SEC14L2, TEC, AMPH, BPIFC, SPTBN2, SYTL3, NSFL1C, APOA1, GLE1, UNC13C, UNC13B, CPTP, ARHGAP26, ARFIP1, PLA2G15, PLA2G7, BIN2, EPN1, APOA5, LPAR1, TREM2, PSD, OPHN1, MYOF, PLA2G5, PSD4, PREX1, LPAR3, PTAFR, RASA4, DYSF, GOT2, AGAP1, JAG1, CARMIL2, PACSIN3, UNC13A, HIP1R, BAIAP3, EPN2, APOC3, BAIAP2L2, SPTBN4, PLA2G2D, BIN1, RASAL1, ARHGAP44, PACSIN1, APOM, MAP1B, SYT16, CAVIN2, APOH, SGIP1 |
| phospholipid scramblase activity | molecular function | ANO6, ANO7, PLSCR4, ANO9, PLSCR1, ANO4, PLSCR2 |
| phospholipid transfer activity | molecular function | MTTP |
| phospholipid transporter activity | molecular function | PITPNB, PITPNA, ABCA4, OSBPL5, OSBPL8, PITPNC1, MFSD2A, ABCB4, PITPNM1, OSBPL10, PITPNM2, CETP, MTTP |
| phospholipid-hydroperoxide glutathione peroxidase activity | molecular function | GPX4 |
| phosphomannomutase activity | molecular function | PMM1 |
| phosphomevalonate kinase activity | molecular function | PMVK |
| phosphopantetheine binding | molecular function | FASN |
| phosphopantothenate--cysteine ligase activity | molecular function | PPCS |
| phosphopantothenoylcysteine decarboxylase activity | molecular function | PPCDC |
| phosphopentomutase activity | molecular function | PGM2 |
| phosphoprotein binding | molecular function | FKBP4, MTOR, RB1, IGF2R, SRC, PLAT, TBK1, PIN1, SNCA, APTX, PHF6, RRAGA, DPYS, PKD2, LRP11, URI1, PRKCSH, YWHAE, GRB2, SAG, SFN, LYN, YWHAB, UBASH3B, TBL2, MID2, MID1, THRAP3, CBX4, GPRIN1, EPB41, TRPV1, PITX2 |
| phosphoprotein phosphatase activity | molecular function | CDC25A, CDC25C, PTEN, ACP1, PTPN11, DUSP6, PTPRJ, PTPDC1, CDKN3, TPTE, MTM1, PPP2R5A, DUSP13, ILKAP, PPM1B, PPP2CA, PTPRR, MDP1, PPP4R1, DUSP22, DUSP8, TNS2, DUSP19, DUSP15, PPEF2, PTPRF, MTMR4, PPP6C, PPP1R3D, PTPRA, PHLPP2, PTPN23, PHPT1, PPP3CB, PTPN2, PPP3CC, UBLCP1, PTPN6, PPP1CB, PPM1L, PTP4A1, DUSP21, PTPRG, PPM1K, PTPRT, DUSP14, PTPN20, PTPN22, PTPRC, PPP2R5D, DUSP5, PPM1J, PPEF1, PTPN13, SSH2, PTPRB, PTPN9, DLG1, TIMM50, CTDSP2, PPM1G, CDC14B, PTPRM, PPP3CA, PPP1R3B, PTPMT1, PTPRN2, PDP1, EYA4, CTDSPL2, DUSP18, PGP, DUSP28, PPTC7, SSH3, PTPRU, PTPN1, PTPRE, PPM1A, UBASH3B, SSU72, CTDSPL, DNAJC6, DUSP1, PPP5C, PPP4C, MTMR3, CTDSP1, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, PTPN5, SSH1, EYA1, PDP2, PTPRS, PTPN14, PPM1E, PGAM5, CTDNEP1, PTPRZ1, PTPN12, PTPN18, PTPRH, PTPN4, DUSP9, DUSP16, PHLPP1, DUPD1, PDXP, CDC25B, DUSP26, EYA2, PTPRD, PTPN3, CPPED1, PPM1H, CTDP1, DUSP2, DUSP10 |
| phosphopyruvate hydratase activity | molecular function | ENO1, ENO2, ENO3 |
| phosphoribosylamine-glycine ligase activity | molecular function | GART |
| phosphoribosylaminoimidazole carboxylase activity | molecular function | PAICS |
| phosphoribosylaminoimidazolecarboxamide formyltransferase activity | molecular function | ATIC |
| phosphoribosylaminoimidazolesuccinocarboxamide synthase activity | molecular function | PAICS |
| phosphoribosylformylglycinamidine cyclo-ligase activity | molecular function | GART |
| phosphoribosylformylglycinamidine synthase activity | molecular function | PFAS |
| phosphoribosylglycinamide formyltransferase activity | molecular function | GART |
| phosphoric diester hydrolase activity | molecular function | APEX1, PLCZ1, PLCH2, PDE4C, GDPD4, PDE1C, GDPD3, PDE7A, PDE1A, SMPD1, SMPDL3A, GDPD2, PDE7B, PLCL1, PDE6A, PLCB2, PLCB3, TDP1, PDE9A, PLCD1, PDE1B, PLCE1, PDE4B, PDE3A, GDPD5, PDE3B, PDE11A, GPCPD1, PDE4D, MPPED2, GDE1, SMPDL3B, PDE5A, PDE8A, PDE10A, PDE2A, PDE6B, ENPP7, ENPP6, PLCD4, PLCG2, PLCH1, PLCL2, PDE8B, GDPD1, PLCXD1, PDE4A |
| phosphoric ester hydrolase activity | molecular function | SYNJ1, INPP5F, SYNJ2, FBP1, PGAP1, SACM1L, FBP2 |
| phosphorus-oxygen lyase activity | molecular function | ADCY2, ADCY10, CD38, GUCY2F, GUCY1B1, GUCY1A2, GUCY1A1, ADCY6, ADCY8, ADCY7, ADCY9, NPR1, GUCY2D, BST1, ADCY4, ADCY5, NPR2 |
| phosphorylase kinase activity | molecular function | PHKB, PHKG2, PHKA2, PHKG1 |
| phosphorylase kinase regulator activity | molecular function | ELP4, PRKAG2, ELP3 |
| phosphorylation-dependent protein binding | molecular function | PTPN6, ANK2, LYN |
| phosphoserine phosphatase activity | molecular function | PSPH, PDXP, DUSP26 |
| phosphoserine residue binding | molecular function | PIN1, NEDD4, YWHAE, YWHAB |
| phosphothreonine residue binding | molecular function | PIN1, FBXW7, NEDD4 |
| phosphotransferase activity, alcohol group as acceptor | molecular function | GK2, ADPGK, GK, ADK, FAM20B, FGGY, HKDC1, FAM20C, SHPK, GK5, FAM20A, GALK2, RBKS, HK2, POMK, XYLB, GALK1, GCK, HK3 |
| phosphotransferase activity, for other substituted phosphate groups | molecular function | CEPT1, CHPT1, PIGG, CDIPT, CRLS1, SELENOI |
| phosphotransferase activity, phosphate group as acceptor | molecular function | AK2, AK4, AK3 |
| phosphotyrosine binding | molecular function | MAPK3, MAPK1, RASA1, PIK3R1, SHC1, SHE, STAP1, SYK, PTPN6, NCK2, ZAP70, IRS1, SH3BP2, SAMSN1, GRB2, ABL1, CBL, VAV2, PIK3R3, ABL2, FGR, PTPN5, CBLB, BCAR3, HCK, LCK, CRK, PIK3R2, VAV1, CBLC, PLCG2, PTPN3, SHB, SHC3, SOCS3, CRKL |
| photoreceptor activity | molecular function | OPN5, CRY1, CRY2, RHO, OPN4, OPN3 |
| phytanate-CoA ligase activity | molecular function | ACSL1, SLC27A2 |
| phytanoyl-CoA dioxygenase activity | molecular function | PHYH |
| phytoceramidase activity | molecular function | ACER3, ASAH2 |
| piRNA binding | molecular function | PIWIL2, PIWIL1, PIWIL4, TEX19 |
| placental growth factor-activated receptor activity | molecular function | FLT1 |
| plasmalogen synthase activity | molecular function | LPCAT2, LPCAT1 |
| plasmanylethanolamine desaturase activity | molecular function | TMEM189 |
| platelet activating factor receptor activity | molecular function | PDGFRB, PDGFRL, PTAFR |
| platelet activating factor receptor binding | molecular function | ARRB2 |
| platelet-activating factor acetyltransferase activity | molecular function | PAFAH1B2, PAFAH1B3, LCAT |
| platelet-derived growth factor alpha-receptor activity | molecular function | PDGFRA |
| platelet-derived growth factor beta-receptor activity | molecular function | PDGFRB, PDGFRL |
| platelet-derived growth factor binding | molecular function | PDGFB, COL3A1, COL4A1, COL2A1, PDGFA, COL1A2, COL6A1, PDGFRB, COL5A1, PDGFRA |
| platelet-derived growth factor receptor binding | molecular function | VEGFA, ITGA5, PTEN, PTPRJ, PDGFB, IL1R1, PDGFD, PDGFA, ITGB3, ERN1, LYN, PDGFRB, PDGFC, PDGFRA |
| platelet-derived growth factor-activated receptor activity | molecular function | PDGFRB |
| plus-end directed microfilament motor activity | molecular function | MYO19, MYO10, MYO3A |
| poly(A) binding | molecular function | PABPC1, KHDRBS1, PABPC3, HNRNPU, DDX1, DDX3X, ZC3H14, SYNCRIP, TIA1, RBMS3, HNRNPDL, ELAVL4, PABPC5, PPIE, PABPC4, EIF4A3, RBPMS |
| poly(A) RNA binding | molecular function | DCN, FKBP4, FMR1, HSP90AA1, CDKN2A, CHD2, HSPB1, ENO1, PARP1, HSPA9, TMSB4X, COA6, PABPC1, PDIA3, KHDRBS1, LIN28B, PUM2, HSPD1, EZR, APEX1, CLK3, SUMO1, DROSHA, ANXA2, TOP2A, HNRNPL, PRDX1, SRSF4, SRSF9, SRSF6, TDRD9, RBMX2, TOP1, RBMX, YLPM1, HIST1H4A, EXOSC10, DYNC1H1, NXF2 |
| poly(ADP-ribose) glycohydrolase activity | molecular function | ADPRS, PARG |
| poly(C) RNA binding | molecular function | HNRNPU, PABPC4 |
| poly(G) binding | molecular function | FMR1, HNRNPU, PATL1, ATXN1, HNRNPDL, PNPT1, MCRS1 |
| poly(U) RNA binding | molecular function | FMR1, PABPC1, KHDRBS1, RPS7, HNRNPC, SSB, PATL1, ATXN1, RBMS3, HNRNPH1, PNPT1, PABPC5, MCRS1, MSI1, PABPC4, DIS3L2 |
| poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends | molecular function | USB1 |
| poly-ADP-D-ribose binding | molecular function | HPF1, RNF146 |
| poly-pyrimidine tract binding | molecular function | U2AF2 |
| polyamine oxidase activity | molecular function | PAOX, SMOX |
| polydeoxyribonucleotide kinase activity | molecular function | CLP1 |
| polymeric immunoglobulin receptor activity | molecular function | PIGR |
| polynucleotide 3'-phosphatase activity | molecular function | APTX |
| polynucleotide 5'-hydroxyl-kinase activity | molecular function | NOL9, CLP1 |
| polynucleotide 5'-phosphatase activity | molecular function | RNGTT, DUSP11 |
| polynucleotide adenylyltransferase activity | molecular function | TUT1, PAPOLA, TENT5C, MTPAP, PAPOLB, TENT2, PAPOLG, TENT5D, TENT4B, TENT4A |
| polyol transmembrane transporter activity | molecular function | AQP9 |
| polypeptide N-acetylgalactosaminyltransferase activity | molecular function | GALNT2, GALNT13, GALNT5, GALNT16, GALNT4, GALNT10, GALNT15, GALNT1, GALNT8, GALNT18, GALNT11, GALNT12, GALNT9, GALNTL6, GALNT17, GALNT7 |
| polyprenol reductase activity | molecular function | SRD5A3 |
| polyribonucleotide nucleotidyltransferase activity | molecular function | PNPT1 |
| polysaccharide binding | molecular function | ENPP2, AGL, ENPP1, CLEC4G, STBD1, VTN, PRG4, CLEC18B |
| polysome binding | molecular function | YBX3, UNK, IMPACT, LIN28A |
| polyubiquitin binding | molecular function | BAG6, RAD23A, RAD23B, ABRAXAS2, OPTN, TNIP3, DZIP3, FAAP20, EPS15, PSMD4, UFD1, BABAM2, AGL, ABRAXAS1, ZFAND2B, AGAP3, UBQLNL, UBQLN3, ZFAND6, SHARPIN, TNIP1, UBL7, HDAC6, TNIP2, SPRTN, DNAJB2, UBQLN4, RAD18, UBXN1 |
| porin activity | molecular function | VDAC2, VDAC1, TOMM40 |
| porphobilinogen synthase activity | molecular function | ALAD |
| potassium channel activator activity | molecular function | LRRC26, LRRC52, LRRC55 |
| potassium channel activity | molecular function | KCNK9, KCNK17, KCNK4, KCNJ10, KCNH6, KCNK2, KCNH3, KCNH4, KCNA4, KCNH2, KCND3, KCNN4, CCDC51, TMEM38B, KCND2, KCNIP4, PKD2, KCND1, KCNQ3, FXYD4, KCNG1, KCNQ2, KCNK10, KCNG4, ABCC9, KCNC4, LRRC52, KCNB1, KCNT2, KCNE4, KCNV1, KCNK18, KCNF1, HCN2, KCNA6, AQP1, KCNV2, KCNS3, KCNIP1, KCNG2, KCNK1, HCN1, KCNK15, KCNE1, KCNA2, KCNIP2, KCNK3, KCNC1, KCNQ4, KCNC2, KCNK7, HCN4, KCNA3, KCNA1, KCNT1, TRPM5, KCNIP3, ABCC8, KCNH8, TMEM175, KCNMA1, KCNC3, KCNH5, KCNG3, KCNK13, KCNQ5, KCNK6, KCNE3, KCNH7 |
| potassium channel inhibitor activity | molecular function | RASA1, WNK3, KCNK2, WNK4, WNK1, CAV3, WNK2, NEDD4L |
| potassium channel regulator activity | molecular function | DPP6, SUMO1, KCNAB1, KCNMB1, KCNMB3, LRRC26, ARPP19, KCNIP4, SGK2, ADRB2, ABCC9, YWHAE, DLG1, AKAP9, NEDD4L, SGK1, SGK3, PRKCZ, KCNE4, CHP1, KCNV1, KCNS3, KCNIP1, KCNAB3, KCNE1, KCNIP2, KCNAB2, PIAS3, DRD2, AMIGO1, KCNIP3, KCNMB4, DRD4, KCNE3 |
| potassium ion binding | molecular function | PDXK, HDAC4, DRG1, KCNA4, PKM, ADPRH, ATP1A2, ATP1B1, ATP1A1, PKLR |
| potassium ion leak channel activity | molecular function | KCNK9, KCNK17, KCNK4, KCNK2, KCNK10, KCNK18, KCNK1, KCNK15, KCNK3, KCNK7, TMEM175, KCNK13, KCNK6 |
| potassium ion transmembrane transporter activity | molecular function | SLC12A2, SLC12A6, AQP1, KCNA1 |
| potassium transmembrane transporter activity, phosphorylative mechanism | molecular function | ATP1A4, ATP1A3, ATP1A2, ATP1A1, ATP4A |
| potassium:chloride symporter activity | molecular function | SLC12A2, SLC12A6, SLC12A4, SLC12A9, SLC12A7, SLC12A5, SLC12A3, SLC12A8 |
| potassium:proton antiporter activity | molecular function | SLC9C1, SLC9A2, SLC9A1, SLC9A7, SLC9A9, SLC9C2, SLC9A6 |
| potassium:proton exchanging ATPase activity | molecular function | ATP4A, ATP4B |
| POZ domain binding | molecular function | ZBTB21, KLHL17 |
| pre-miRNA binding | molecular function | DICER1, DHX36, PRKRA, TARBP2, RAN |
| pre-mRNA 3'-splice site binding | molecular function | SLU7, U2AF1L4, ZRSR2, U2AF1L5, U2AF1, U2AF2 |
| pre-mRNA 5'-splice site binding | molecular function | SNRPC |
| pre-mRNA binding | molecular function | SRSF6, HNRNPU, LSM1, HNRNPA1, CELF5, RBM22, TRA2B, TARBP2, CELF4, CELF2, SRSF2 |
| pre-mRNA branch point binding | molecular function | SF1 |
| pre-mRNA intronic binding | molecular function | SOX9, HNRNPL, HNRNPA2B1, EP300, PRPF8, RNPC3, RBM4, RBM7, RBM24 |
| pre-mRNA intronic pyrimidine-rich binding | molecular function | ELAVL4, RBM4 |
| prenylated protein tyrosine phosphatase activity | molecular function | PTP4A3 |
| prenylcysteine oxidase activity | molecular function | PCYOX1 |
| prenyltransferase activity | molecular function | COX10, FNTA, RABGGTB, UBIAD1, PDSS2, NUS1, PGGT1B, PTAR1, FNTB, PDSS1 |
| preribosome binding | molecular function | NVL |
| primary amine oxidase activity | molecular function | AOC2, VCAM1, AOC1, AOC3 |
| primary miRNA binding | molecular function | DROSHA, PUS10, SMAD2, SRF, SMAD3 |
| pristanate-CoA ligase activity | molecular function | SLC27A2 |
| pristanoyl-CoA oxidase activity | molecular function | ACOX3 |
| procollagen galactosyltransferase activity | molecular function | COLGALT2, CERCAM, PLOD3, COLGALT1 |
| procollagen-lysine 5-dioxygenase activity | molecular function | PLOD1, PLOD2, PLOD3 |
| procollagen-proline 3-dioxygenase activity | molecular function | P3H3, P3H1 |
| procollagen-proline 4-dioxygenase activity | molecular function | P4HB, P4HA3, P4HA1, P4HA2 |
| profilin binding | molecular function | VASP, WIPF1, CTTN, RHOQ, EVL, ACTG1, ENAH, HTT, FMNL1 |
| progesterone receptor binding | molecular function | NCOA2, PRMT2, NCOA1 |
| prolactin receptor activity | molecular function | PRLR |
| prolactin receptor binding | molecular function | PRL, GH1 |
| prolactin-releasing peptide receptor binding | molecular function | PRLH |
| proline dehydrogenase activity | molecular function | PRODH2 |
| proline dipeptidase activity | molecular function | PEPD |
| proline-rich region binding | molecular function | TCERG1, BAIAP2L1, BAIAP2, ABI2, CCND1, WBP4, NEDD4, CYLD, GHR, ABL1, YAP1, GAREM1, GIGYF2, CSK, SH3D19, RABAC1, APBB1, ITSN1 |
| proline-tRNA ligase activity | molecular function | EPRS1, PARS2 |
| proline:sodium symporter activity | molecular function | SLC6A15, SLC6A7 |
| promoter-specific chromatin binding | molecular function | DNMT1, EZH2, RBL1, HDAC4, HNRNPU, RBL2, KLF4, ISL1, TAF5, E2F4, USP3, ZNF750, HDAC2, GTF2F1, PCGF2, SUZ12, PCGF1, EGR1, GTF2B, EHMT2, PPARGC1A, PRDM1, PDX1, ZNF609, GADD45A, ZNF683, WDR13, TAF5L, BMI1, NIPBL, MACROH2A1, FOXC2, SETDB1, NUP98, TAF10, ERCC4, NRL, POU4F2, NFE2L1, MYOD1, FOXO4, FOXC1, GLI2, POLR2A, PRDM15, TP53 |
| propane-1,3-diamine oxidase activity | molecular function | AOC1 |
| propanoyl-CoA C-acyltransferase activity | molecular function | SCP2 |
| propionate CoA-transferase activity | molecular function | ACSM3 |
| propionate transmembrane transporter activity | molecular function | SLC5A8 |
| propionate-CoA ligase activity | molecular function | ACSS3, ACSS1, ACSM3, ACSS2 |
| propionyl-CoA C2-trimethyltridecanoyltransferase activity | molecular function | SCP2 |
| propionyl-CoA carboxylase activity | molecular function | PCCA, PCCB |
| prosaposin receptor activity | molecular function | GPR37L1 |
| prostacyclin receptor activity | molecular function | PTGIR |
| prostaglandin D receptor activity | molecular function | PTGDR, PTGDR2 |
| prostaglandin D2 11-ketoreductase activity | molecular function | AKR1C3 |
| prostaglandin E receptor activity | molecular function | HPGD, PTGER2, PTGER1, PTGER3, PTGER4 |
| prostaglandin F receptor activity | molecular function | PTGDR2 |
| prostaglandin H2 endoperoxidase reductase activity | molecular function | AKR1C3 |
| prostaglandin J receptor activity | molecular function | PTGDR, PTGDR2 |
| prostaglandin receptor activity | molecular function | PPARG, PTGER1, PTGER3, PTGER4 |
| prostaglandin transmembrane transporter activity | molecular function | SLCO2A1 |
| prostaglandin-D synthase activity | molecular function | PTGDS, PTGES, HPGDS |
| prostaglandin-E synthase activity | molecular function | PTGES3, PTGES2, PTGES |
| prostaglandin-E2 9-reductase activity | molecular function | CBR1 |
| prostaglandin-endoperoxide synthase activity | molecular function | PTGS1, PTGS2 |
| prostaglandin-F synthase activity | molecular function | AKR1C3, PRXL2B |
| prostaglandin-I synthase activity | molecular function | PTGIS |
| protease binding | molecular function | SERPINC1, TIMP1, TNF, TP53, BCL2, FAS, INSL3, BRCA2, VWF, SERPINE1, CASP3, SERPINA1, ITGB1, F3, A2M, SERPINA5, ITGAV, ACR, KIT, POLG, FN1, SEMG2, ANXA2, ELANE, ECM1, TIMP2, MALT1, PRNP, SRI, CCBE1, ALPI, BCL10, BDKRB2, DERL1, IL1R1, XBP1, SERPINB6, CSTB, LONP2, COL3A1, RYR1, TIMP3, LDLR, SERPINB9, PSAP, PANX1, ANXA9, SERPINF2, FADD, NTRK2, TTN, PINK1, CFLAR, ADRM1, NFRKB, SLC2A13, CHL1, ATP9A, FLOT1, ITGB3, COL1A2, CDK5R1, MBP, CSTA, DPP4, SERPINB3, TRIP4, RNF139, UBC, THAP5, OS9, LRP1, DVL3, TIMP4, PYCARD, TNFRSF10A, CD28, SELL, FURIN, COMP, INS, ITGA3, ADAMTS4, SLC6A3, SH3PXD2A, A2ML1, BIN1, NDUFS7, CRADD, STIM1 |
| proteasome binding | molecular function | BAG6, USP13, PSMG1, USP14, PSMD14, ZFAND1, UBD, ADRM1, SACS, PSMF1, UCHL5, DNAJB2 |
| proteasome core complex binding | molecular function | ALAD |
| proteasome regulatory particle binding | molecular function | UBXN1 |
| proteasome-activating ATPase activity | molecular function | PSMC2, PSMC4, PSMC1 |
| protein adenylylhydrolase activity | molecular function | FICD |
| protein adenylyltransferase activity | molecular function | FICD, SELENOO |
| protein ADP-ribosylase activity | molecular function | TNKS, ZC3HAV1, PARP12, PARP14, TIPARP, PARP3, PARP16, TNKS2, PARP6, PARP8, PARP4, PARP11, PARP10 |
| protein anchor | molecular function | CIB1, RAPSN, LPL, NUP153, PDCD6, TPR, MYH9, SUN2, SLC4A1, AKAP6 |
| protein antigen binding | molecular function | ITGA4, KLRC1, KLRC2, PLG, PPP2R1A, EP400 |
| protein binding | molecular function | NR5A2, SOD1, EGFR, F10, SERPINC1, TIMP1, EGF, TGFB1, CGA, FSHB, TNF, APOE, ESR1, TP53, CYP1A1, IL4, IL6, ICAM1, PGR, MMP2, INHBA, IL6R, CXCL8, AR, BCL2, TGFB3, VDR, ACE, MYH7, HLA-DRB1, MMP9, LIF, VEGFA, RAG1, CD44, IL1RN, ATF3, TNFRSF1A, WT1, TNFRSF1B, IL11, KITLG, IL10, ANOS1, FSHR, BRD2, FAS, IL12A, CASP1, NOS3, ADM, PTGS2, AHR, BRCA1, IL6ST, SOX9, NRIP1, LIG4, TNFSF10, BRCA2, CASP6, SOX10, GNAS, FKBP4, FMR1, BAX, NR5A1, IL18, BAK1, HIF1A, AMHR2, TSSK4, NOSTRIN, CATSPER1, ESR2, BCL2L2, CATSPER2, TSSK6, IL23A, DAZ1, FKBPL, DNMT3L, NDRG2, FAM50B, TERT, BIRC5, OGG1, ZEB2, NR1I2, USP1, CCNB2, IGF2, APOB, VWF, ERBB2, SERPINE1, CDK1, HSP90AA1, ERCC1, SP1, ABCB1, HMOX1, NAT2, MTHFD1, CFTR, CCNB1, FLT1, ERCC2, XRCC1, HNF1A, FGFR2, FGFR3, XPA, DNMT1, MAPK3, MAPK1, TYK2, WEE1, CDC25A, CDC25C, AXL, AKT1, HSPA4, HNF1B, KDR, STAT1, CASP3, CDKN2A, FASLG, GSK3B, NR0B1, CASP9, UBE2B, SNRPN, S100A12, HSF1, MDM2, E2F1, HSF2, ATM, GAS6, KANK1, STAT4, CASP8, EZH2, NFE2L2, UBR2, CTCFL, MTR, CIB1, USP26, WDR11, MBD2, DNMT3B, MT |
| protein binding involved in heterotypic cell-cell adhesion | molecular function | CD47, GLDN, NRCAM, NFASC |
| protein binding involved in protein folding | molecular function | HSPA1A, HSPA1B, HSPA8, CD74, HSPA14, CCT2, RIC3, DNAJB8, ZMYND10, PFDN1, HSPA13, DNAJB1, FKBP8, HSPA6, DFFA, CALR, HSPB1 |
| protein binding, bridging | molecular function | FKBP4, FLRT3, HSPA8, COL11A1, OPTN, TRIM17, PSMC6, PPP2R3A, TCAP, ANK3, VPS18, ST13, FBXW7, FLRT1, NEFH, NCK1, BCL3, TRDN, COL11A2, HCFC1, CNKSR1, ADAP2, STUB1, SLC9A1, CUX1, FLRT2, SH2D1B, TIRAP, GATAD2A, MEN1, CAV2, SERINC1, DDX20, FSCN3, PDCD6, COL1A2, PEX3, ANK2, PPP4R2, SYNPO2, ICE1, NUFIP1, DVL2, FRMD4A, RAD50, ERG28, COL8A2, MMS19, BFAR, CBX5, CRK, ARPC4, COL19A1, FSCN2, RPTOR, TRAF2, FSCN1, AMFR, CRADD, DDB1, TRIM6, TRIM5, NEFL, CAV1, TRIM22 |
| protein C-terminal carboxyl O-methyltransferase activity | molecular function | LCMT1 |
| protein C-terminal leucine carboxyl O-methyltransferase activity | molecular function | LCMT1 |
| protein C-terminal methylesterase activity | molecular function | PPME1 |
| protein C-terminus binding | molecular function | LIG4, ERBB2, ERCC1, SP1, ERCC2, CIB1, VIM, CTNNB1, PABPC1, SRC, PROP1, YWHAQ, CDC20, PICK1, PEX10, TOP2A, ECM1, MSH2, DYNLL1, MAPK14, ATP2A2, CCN2, EFHC1, BLOC1S2, SIAH1, OPTN, JAK2, PIAS1, PFKM, COIL, GPSM2, NEIL1, BAIAP2, XRCC5, CDK7, PPP2CA, SARNP, CALCOCO1, IFT52, BCL10, SREBF2, TFCP2, NPAT, PPP1R9B, VTA1, VPS4B, SH3GL2, MAPRE3, FOXN3, TRIM3, MPDZ, YEATS4, BCAM, ERCC6, VPS36, PCGF1, MID1IP1, KPNA3, DAB2, ITGB3BP, SH3GL3, PEX26, SNTG1, SYT1, PEX5, TAF13, CEP120, TOPBP1, CITED1, FBLN5, XRCC6, PHB2, ATF4, FBLN1, CENPF, CAV3, DST, IFT46, DBNL, GRIP1, PEX12, MKI67, MRE11, DGKZ, PDZD3, MCHR1, SDCBP2, ATXN1, MAD2L1, PXK, SCLT1, SCAF4, PRDX3, EP300, DLG1, NIPBL, PRRC2C, TNNI3K, KSR1, ABL1, STIP1, XRCC4, NUMA1, USP7, HIC2, MAGI1, AGO2, TCF4, TOP2B, CTBP1, SNF8, RBFOX1, PEX1, YWHAB, YAP1, HSPG2, ERCC4, CD2AP, TBL1X, SASH1, EML2, DLG4, MAPRE1, PPP1R9A, PEX16, ATP1B1, MAP2K1, DLG3, MED12, SIPA1, CEP250, NCL, CIITA, HESX1, MIF4GD, TAX1BP3, HRAS, SLC9A3R2, MYO1C, KCNK3, LCK, CORO1A, ZBTB16, CNRIP1, CSK, DNM1, RABAC1, P |
| protein carboxyl O-methyltransferase activity | molecular function | ARMT1 |
| protein channel activity | molecular function | MCL1 |
| protein complex binding | molecular function | ESR1, ICAM1, FAS, BAX, HIF1A, HNF1B, CASP3, MTHFR, ATM, CASP8, ITGB1, GNAO1, FGFR1, CTNNB1, INSR, SRC, KHDRBS1, NCOA2, EZR, APEX1, RAP1A, TWF1, SIN3A, MT-CYB, MYC, ANXA6, VDAC1 |
| protein deacetylase activity | molecular function | SIN3A, HDAC4, HDAC2, HDAC9, SIRT2, HDAC7, HDAC3, SIRT6, HDAC6, HDAC10, HDAC5 |
| protein dimerization activity | molecular function | AR, AHR, HIF1A, ERBB2, HNF1A, ATM, ARNT2, STAT3, NCOA2, SOHLH1, MEF2A, STRA8, CLOCK, PIP, USF1, NPAS2, SOHLH2, MYC, MYCN, DAO, E2F5, ZMYM1, OLIG3, MAX, E2F4, NARS1, NHLH1, HIF3A, ST13, SREBF2, BHLHE22, NEUROG2, BTRC, STAT5B, POLR1C, LYL1, MXD1, HES1, ANO6, NEUROD6, ASCL3, TCFL5, NCOA3, CREB3, PPP3CB, CCL11, ASCL4, ASCL2, EBF3, MXI1, OLIG1, NEUROG1, HES6, EBF4, BHLHE40, MSGN1, E2F3, MITF, POLR1D, ID3, MEF2C, HPS4, AIFM1, SIM1, ANO7, NEUROD4, ZBED1, ASCL1, E2F2, HES7, ZBED4, POLR2J, NHLH2, NEUROD1, NPAS3, PDCD6, SP100, ADCY8, GARS1, ID4, PPP3CA, TWIST1, NCOA1, MLXIP, E2F6, TFE3, MEF2D, NSMCE3, TCF4, NSMCE1, EBF1, BOK, BHLHA15, MGA, MNT, EPAS1, HEY2, MXD4, SLC4A11, HES4, SREBF1, ID2, RILP, TFEC, SRF, CEACAM1, POLR2C, RILPL2, MXD3, PYCARD, ARNTL, MYOD1, MYOG, TAL2, HEY1, MYCL, HPS1, NPAS1, MESP1, TFEB, TCF15, MLX, AHRR, ANO1, NPAS4, ANO2, PEF1, MEF2B, SIM2, USF2, TFAP4, ANO4, RILPL1, FIGLA, THAP12, HAND2, PTF1A, BHLHE41, HES2 |
| protein disulfide isomerase activity | molecular function | PDIA3, P4HB, PDIA6, CRELD2, CRELD1, GLRX2, QSOX1, PDIA4, QSOX2, ERO1A, ERP27, ITGB3, ERP44, ERO1B, TXNDC5, PDIA5, PIGK, PDIA2, TMX3 |
| protein disulfide oxidoreductase activity | molecular function | GSTK1, TXNDC8, TXNDC2, GLRX5, DNAJC10, TXNRD1, SH3BGRL3, GLRX2, GLRX3, ERO1A, PTGES2, STAB1, ERO1B, GLRX, TXN2, SCO2, GFER, STAB2 |
| protein domain specific binding | molecular function | IL1B, ERCC1, XPA, DNMT1, NR0B1, NFE2L2, MBD2, ITGB1, MTOR, CSNK2B, PLAUR, INSR, HSPA5, SRC, CABYR, EZR, GJA1, YWHAQ, PTPN11, PICK1, DICER1, NF2, PKD1, TP63, HIST1H4A, DYNLL1, TADA3, SKIL, IKZF1, TFDP1, KCNAB1, IPCEF1, SENP2, MRPL17, CHMP2A, PIAS1, HNRNPM, GPSM2, RABEP1, E2F4, CNOT1, HNRNPA1, PRKAR2A, IQGAP1, MLF1, RAP2B, SKP1, CBX3, ZNF521, ST13, RAB27A, YWHAH, SCAF1, XPO1, NCK1, GTF2F1, TRIM11, LIN7C, SLC9A3R1, KCTD13, TRIM9, RNF41, STX18, ACSL3, GUSB, GNAI3, RAB6A, WARS1, FOXA1, TRA2B, HGS, M6PR, MPP7, ARHGEF4, BHLHE40, AP2A2, DDC, IST1, WNT3A, ARF1, TDG, CHMP1A, HOMER2, STMN3, RCC2, RAB27B, SKI, LAMP2, YWHAZ, ID3, VRK2, IRS2, ACTN2, NEDD4, AIDA, PHRF1, DBNL, CASP2, STX1B, MITD1, VAPA, DDX20, TUBB, CALM1, CALM2, CALM3, DDX6, CNOT9, CACYBP, EPB41L5, IKBKG, SP100, MECP2, YWHAE, SRSF7, KHDRBS3, GRB2, PRKDC, BASP1, TWIST1, SHC4, DVL2, ABL1, ARL1, NUMA1, MRPS31, MAP3K5, TRPS1, SSX2IP, NFASC, POU2F2, RDX, ARFIP1, ICA1, CTBP1, TFDP2, NLRP1, YWHAB, CITED2, STRN4, FAF1, TBL1X, DFFB, LAMP1, ESRRA, TGM2, CAPG, PPP1R9A |
| protein geranylgeranyltransferase activity | molecular function | FNTA, PGGT1B |
| protein heterodimerization activity | molecular function | EGFR, TGFB1, TP53, INHBA, BCL2, TGFB3, MYH7, VEGFA, ATF3, IL12A, AHR, SOX9, FMR1, BAX, BAK1, HIF1A, BCL2L2, BIRC5, ERBB2, HNF1A, AXL, HNF1B, SRY, ADCY2, ARNT2, DMRT1, TLR2, ITGB1, ENO1, HEXA, HEXB, PGF, BAD, HGF, KCNK9, CABYR, RAF1, H2AFX, MEF2A, MCL1, SOS1, INHA, TOP2A, USF1, PAFAH1B2, H2BFWT, TAF4B, KATNB1, LIMK2, HIST1H4A, SUPT4H1, H2AZ2, BCL11A, ALG2, SRI, DDIT3, GTF2A2, TAF12, MIGA1, QTRT2, ZHX1, FZD9, SEPHS1, FXR1, PPP2CA, EXT1, MAPK6, RALGAPA1, SNX2, ATF1, PIK3R1, BDKRB2, DR1, YWHAH, UGT1A8, TAF9B, POLE3, FZD4, KATNA1, VAPB, PDGFB, CYBB, P4HB, XBP1, MAPK4, IRAK1, H2BC21, H2AC12, MACROH2A2, SMC3, IRAK2, SUPT3H, NAE1, CENPT, JAM3, H2AZ1, H2BC5, RRAGA, ZNF397, UGT1A4, TPM4, RALGAPB, H2AJ, SUPT5H, BHLHE40, MAFG, SYT1, ABCG1, RUNX1, TAF13, TAF7, PDSS2, H2AC6, UBA2, SYT5, H2BC12, CYBA, CEACAM8, MEF2C, TAF11, PHB2, IRAK3, ATF4, H2AC7, AGTR1, H2BC3, SIM1, TAF3, SUPT7L, ADRA2A, GADD45A, ADRA1A, CEACAM6, NR4A2, CAV2, H2AC20, H2AC21, SDCBP2, VAPA, TAF6L, PDGFA, CD3E, SRGAP2C, SOS2, NEUROD1, NFYC, RALGAPA2, NPAS3, |
| protein histidine kinase activity | molecular function | NME2 |
| protein histidine phosphatase activity | molecular function | PHPT1, LHPP, MINPP1 |
| protein homodimerization activity | molecular function | SOD1, TGFB1, APOE, IL6R, BCL2, MYH7, VEGFA, RAG1, ATF3, PTGS2, IL6ST, HSD17B4, PLOD1, FMR1, BAX, BAK1, BCL2L2, TERT, BIRC5, VWF, HSP90AA1, SP1, GSTM1, HMOX1, HNF1A, FGFR2, XPA, PON1, HNF1B, STAT1, NR0B1, HSF2, RNF17, DMRT1, HEXB, MGST1, FGFR1, PRPS2, PRLR, ACAT1, CBS, PGF, PRDX4, PARK7, DMRT2, CAT, KIT, BMP4, CCL5, HLA-G, NOS2, CHKA, XDH, IZUMO1, APOA1BP, MUC13, KCNK9, PDXK, IDH1, G6PD, NR2F2, EPHX2, MCL1, 41153, DROSHA, FLRT3, DNM1L, RNF8, NTRK1, TOP2A, USF1, PAFAH1B2, CCDC103, DSCAML1, CD8A, ANXA6, CSF1, S100A11, GDNF, MSH2, GAMT, ZNF174, CECR1, PEX7, CIDEA, PRPS1L1, CAMK2B, CAMK2D, RAB11FIP2, CEP57, DPY30, BCL11A, GRPEL1, NRBP1, NUDT21, NPM1, ST6GAL1, GLDC, IMPA1, SHMT1, DDIT3, GTF2A2, NDP, KARS1, RABEP1, KYNU, LRRFIP1, NADK2, PHETA2, MIGA1, SPPL2A, TSG101, PDCD10, FICD, QTRT2, UHRF1BP1L, FZD9, TPST1, GLA, GYG1, SEPHS1, FXR1, EXT1, CARM1, SUPV3L1, ALS2, MFF, RTN4, ZBTB4, GRHPR, NUDT5, SNX6, SNX2, COQ9, PEX11B, LPL, EPRS1, SFPQ, RRM2, ATIC, PSMD7, BST2, STK4, SMAD4, NLGN4X, UGT1A8, MTPAP, THAP1, FZD4, SH3GL |
| protein kinase A binding | molecular function | AKAP4, MYRIP, AKAP12, RPS3, AKAP7, GSKIP, WASF2, RDX, AKAP13, WASF1, AKAP10, DACT1, AKAP11, AKAP5, AKAIN1, SPHKAP, LRRK2, CRYBG3, RARA, AKAP6, DACT2 |
| protein kinase A catalytic subunit binding | molecular function | SOX9, GSK3B, EZR, PJA2, PRKAR2A, RYR2, PKIA, PRKAR2B, PRKAR1B, CSK |
| protein kinase A regulatory subunit binding | molecular function | EZR, PJA2, ACBD3, ARFGEF1, AKAP14, WASF3, AKAP8, PRKACB, ARFGEF2, RYR2, AKAP7, GSKIP, PRRC1, AKAP1, AKAP9, C2orf88, WASF2, WASF1, AKAP11, AKAP5, AKAP8L, AKAP6 |
| protein kinase activator activity | molecular function | PIK3CA, CAB39, MARK2, DUSP19, PRKAG2, RPLP1, WNK1, CDK5R1, STRADA, SPDYA, TOM1L1, AGAP2, GPRC5A, RGCC, DBF4B, GPRC5B, WNT11, MT3, NCKAP1L, MADD, GPRC5C, EPO, MAPK8IP2, RPTOR, GPRC5D |
| protein kinase activity | molecular function | EGFR, SOX9, AMHR2, TSSK4, TSSK6, AURKC, ERBB2, CDK1, FLT1, ERCC2, FGFR2, FGFR3, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, KDR, GSK3B, ATM, FGFR1, CSNK2A2, MTOR, BRSK2, INSR, YES1, IGF1R, KIT, SRC, CCL5, MAPK8, ATR, BMPR2, LMTK2, CDC7, RAF1, MAK, CLK3, CDK9, NTRK1, DDR1, CAMK4, MAST2, LIMK2, DMPK, MAPK14, ROR1, CAMK2B, CAMK2D, PDK4, PAN3, WNK3, TBK1, MOK, TRIM24, JAK2, GRK5, CSNK1A1, STK3, DYRK1A, PDK3, NEK8, STK36, PLK2, MAP3K4, EEF2K, DYRK3, KALRN, MARK3, CDK7, CCL8, MAP4K2, MAPK6, COQ8A, NEK1, RPS6KB2, CIT, CDK14, ACVR1B, STK4, PTK7, MAPK11, MARK2, MAP4K1, WNK4, PPP1R9B, STK31, PEAK1, ALK, DYRK1B, PRKAB1, MAP3K7, RPS6KB1, PRKCH, LTK, MAPK4, CSNK1E, IRAK1, TLK2, UHMK1, TBCK, NPRL2, COQ8B, PASK, EIF2AK1, MAP3K20, STK17A, RPS6KL1, STK25, IRAK2, BUB1, BUB1B, STK17B, CCL3, PRKACB, EPHB2, TIE1, ACVR1, PTK2, PRKD1, STK38, CAMK1D, MASTL, CDK15, ROCK2, BRAF, GRK4, FLT4, BMPR1A, SYK, CLK2, HIPK1, MAPKAPK5, NEK11, SRPK1, STRADB, MAP3K8, PRKX, SRPK2, CDKL3, HIPK4, TAOK2, STK10, ROS1, CCND1, NEK3, ITK, ACVR2B, MAP3K15, MAP4K |
| protein kinase B binding | molecular function | BAD, BCL10, ANKRD2, CCDC88A, PINK1, PDE3B, TRAF6, APPL1, ARRB2, SRSF5, RARA |
| protein kinase binding | molecular function | TP53, HIF1A, HSP90AA1, CCNB1, MAPK1, CDC25A, CDC25C, AKT1, CDKN2A, GSK3B, CASP9, E2F1, CIB1, HSPB1, ITGB1, PARP1, CTNNB1, STAT3, MTOR, IFNAR2, PTEN, BRSK2, BAD, PIWIL1, INSR, SRC, GATA4, CDC42, MEF2A, LIPE, PLA2G6, PGAM1, USF1, PKD1, SPAG16, TCF7L2, CD8A, CCNA2, VDAC1, MSH2, FOXM1, PTPRJ, PAM, HDAC4, RPS7, RPS6, EEF1A1, HNRNPA0, BORA, RAB11FIP2, BCL11A, JAK2, KIF20A, NPM1, CIR1, CACUL1, RB1CC1, PDCD10, INKA2, PPP1R12A, IQGAP1, SLC12A2, PTPRR, MAPK6, ELP2, CCNYL1, TRIB3, CDK5RAP1, ZBTB4, PARN, BCL10, SHC1, PXN, ARHGEF7, RHOU, CCNY, ADIPOR1, ERRFI1, MAPK8IP1, PRKAB1, BCL2L11, CCNT1, NEFH, XBP1, PTN, MAPK4, RPS19, NSF, DAB2IP, SPDYE1, TRIM58, SH3GL2, MAPRE3, DVL1, RPS3, PEBP1, UTRN, CKS1B, PTK2, KIF14, CD226, RBBP6, INKA1, CDK5RAP2, PTPN23, FAM83D, PRKAG2, STAP1, TPRKB, PRKN, CTNND1, ACSL3, TFRC, PTPN2, WARS1, SYK, TRAF3, FAM83B, CSPG4, SPRED1, GCSAM, RNF138, RYR2, CDK5RAP3, ARHGAP33, PTPN6, IL15RA, USP37, GCN1, BICD1, AKAP7, GSKIP, SLC12A6, BAG5, PPME1, RHOD, SOCS1, PRC1, AP2A2, CEP43, EEF2, CCND1, CTBP2, BCAR1 |
| protein kinase C activity | molecular function | PRKCH, PRKD1, PRKCQ, PKN2, PKN3, PRKD3, PRKCB, PRKCZ, PRKCD, PRKCE, PRKD2, PKN1, PRKCG |
| protein kinase C binding | molecular function | AKT1, HSPB1, ITGAV, SRC, C1QBP, PICK1, TOP2A, HINT1, GRK5, NELL1, RACK1, HDAC9, PLEK, CCDC88A, SDC4, TDG, GLRX3, FEZ1, IRS1, TIRAP, SQSTM1, PRKCB, DSP, PRKCSH, ADCY6, ABL1, ADAM9, HDAC7, TOP2B, CAVIN3, PARD6A, PDLIM5, PARD6B, LDB3, NELL2, PKP2, DACT1, AVPR1B, YWHAG, SRSF2, TWF2, ADCY4, PRKD2, PKN1, MARCKS, HDAC5, KIAA1614, PARD6G, UGT1A7, UGT1A10, CAVIN2, DACT2 |
| protein kinase C inhibitor activity | molecular function | HSPB1, SFN, YWHAG |
| protein kinase inhibitor activity | molecular function | DCN, FLRT3, LRRC4C, NPM1, TRIB3, DUSP19, MAPK8IP1, NCK1, SNCA, MBIP, PPP1R1B, GSKIP, SOCS1, TRIB1, WNK1, TAOK3, PKIG, ITPRIP, CDKN1B, PKIA, DUS2, SH3BP5, PKIB, DNAJC3, CHP1, SMCR8, TESC, CDKN1A, INCA1, GMFB, QARS1, TRIB2, CAMK2N2, CDKN1C, GMFG, IMPACT, SH3BP5L, SOCS3 |
| protein kinase regulator activity | molecular function | CSNK2B, PRKAG2, GCN1, KIDINS220, APC, RAC2, FAF1, ANKRD54, ATG13, CDC37 |
| protein methylesterase activity | molecular function | PPME1 |
| protein methyltransferase activity | molecular function | CARM1, FAM98A, METTL21A, FAM98B, LCMT1, NTMT1, METTL22, PRMT1, HEMK1, N6AMT1 |
| protein N-acetylglucosaminyltransferase activity | molecular function | OGT, EOGT, B3GNT8 |
| protein N-terminus binding | molecular function | TGFB1, TP53, DCN, VWF, ERCC2, ATM, PARP1, CLU, CSNK2A2, YWHAQ, RASSF1, NBN, ALOX5AP, PEX19, EIF3E, GTF2H3, TDRD7, ALG2, RPS21, PDCD10, MORF4L1, RPA2, SMARCA4, NPAT, CFAP36, SRRM2, RND2, STX5, APTX, SCFD1, SLC9A3R1, EIF5A, ERCC6, SMARCE1, NCOA3, HAX1, TSC1, ZWINT, TARBP2, ERCC5, PEX5, RELA, TAF11, CHMP6, PHB2, FEZ1, GAD1, MEN1, GADD45A, SLA2, CALM3, BIRC2, MAU2, MECP2, CSNK2A1, NIPBL, SDCBP, NCOA1, NCOR2, EXOC5, RBPJ, TRAF6, PEX14, EXOC4, SNF8, HYPK, ERCC4, SMARCC1, SGF29, PDLIM5, DCTN4, ARF6, MAP2K1, NFE2, VPS25, THAP7, HESX1, ZMYND8, SCT, GLRX, MNAT1, KCNIP2, PIAS3, NTSR1, MYO7A, ACTN4, SYNGR3, SLC6A3, EPB41, ACOX1, EXOC2, HSPA1A, HSPA1B, KLHL13 |
| protein O-GlcNAc transferase activity | molecular function | OGT, POMGNT2, EOGT |
| protein phosphatase 1 binding | molecular function | PPP1R9B, STAU1, PPP1R3D, SHOC2, PPP1R3C, PHACTR1, PPP1R3B, PPP1R16B, FER, SH3RF2, PPP1R15A, PPP1R16A, PPP1R9A, AKAP11, PPP1R11, PHACTR4, PHACTR3, SMTNL1, CDC5L |
| protein phosphatase 2A binding | molecular function | TP53, BCL2, AKT1, FOXO1, PPP2R2A, CTTNBP2NL, DAB2IP, MASTL, PPME1, HMGCR, ARPP19, EIF4EBP1, SMG7, STRN, BOD1L2, ANKLE2, BOD1, ADCY8, STRN3, IGBP1, PTPN1, STRN4, BOD1L1, GRIN3A, MFHAS1, SMG5, SLC6A3 |
| protein phosphatase 2B binding | molecular function | SOD1, BAD, PPP3CB, SLC9A1, AKAP5, MYOZ2 |
| protein phosphatase activator activity | molecular function | PPP2R5A, PPP2R5C, PPP2R5E, PPP2R5D, CALM1, CALM2, CALM3, PPP1R15A, PHACTR4, B3GAT3 |
| protein phosphatase binding | molecular function | EGFR, TP53, BCL2, ERBB2, HSP90AA1, CTNNB1, STAT3, BAD, INSR, PPARG, MAPK14, SNX3, TBK1, RPA2, IQGAP1, PIK3R1, PXN, AP3B1, HSP90B1, GTF2F1, RACK1, KIFAP3, MTMR4, PPP6R2, PTK2, ANAPC5, SHOC2, KCNN4, FLT4, TRAF3, PPME1, ROS1, STX17, IKBKE, ANAPC7, PPP1R3C, IRS2, PTPRT, MAP2K7, SKAP1, PARD3, FCRL2, PPP6R3, VRK3, MTMR9, JAK1, CDKN1B, GRB2, MAP3K5, CDC27, DLG4, MTMR3, DLG3, MYO16, CEACAM1, CD33, CDH5, JUP, CD22, PDLIM4, KAT2A, LCK, FBXL2, PIK3R2, CSK, CSF1R, JAK3, ANAPC4, HSF4, STAT6, TRAF2, MVP, NEK2, EIF2AK3 |
| protein phosphatase inhibitor activity | molecular function | LMTK2, PPP1R2, ELFN2, PPP1R14A, PPP1R36, PPP1R9B, PTN, PPP1R35, PPP1R1B, PPP1R14C, PPME1, ARPP19, PPP1R8, PPP1R1A, PHACTR1, BOD1L2, URI1, BOD1, SAG, SH3RF2, PPP1R1C, BOD1L1, PPP1R26, PPP1R11, SET, PPP1R10, PPP1R27, PHACTR3, ELFN1, CABIN1, PHACTR2 |
| protein phosphatase regulator activity | molecular function | PPP2R2B, PPP2R3A, PPP2R5A, PPP1R7, PPP4R1, PPP2R2A, PPP2R1B, PPP6R2, PPP2R5C, SHOC2, PPP1R1B, PPP2R2C, PPME1, ARPP19, PPP1R8, PPP2R5E, PHACTR1, PPP2R5D, PPP6R3, ANKLE2, PPP4R2, PPP1R3B, PPP1R16B, PPP2R2D, PPP4R4, IGBP1, PPP1R15A, PPP1R16A, EIF2AK2, SET, PHACTR4, PHACTR3, PPP2R1A |
| protein phosphorylated amino acid binding | molecular function | BTRC, CRK |
| protein prenyltransferase activity | molecular function | FNTA, PTAR1 |
| protein propionyltransferase activity | molecular function | EP300 |
| protein self-association | molecular function | TP53, CCL5, MALT1, VPS41, TMEM190, GPSM2, DYRK1A, SGTA, MDH2, BCL10, SPTBN5, PTH1R, KCTD9, NKX3-1, MYD88, SLC9A3R1, CTSC, RYR2, TDG, RSAD2, FOXP1, SYP, CNTN2, TRIM32, TTN, ATXN1, DVL2, CCDC88C, SVIP, CD2, AGXT, ACVR2A, ZNF639, DMTN, CRK, ADAM8, PCSK9, FHOD1, AGA, SMTNL1 |
| protein sequestering activity | molecular function | PEX5, CDKN1A, TMC8 |
| protein serine/threonine kinase activator activity | molecular function | TGFB1, IGF2, LTF, CAB39, DDX3X, STK3, DBF4, IQGAP1, ALS2, STK4, DAZAP2, PARP16, CALM1, CALM2, CALM3, MAP2K2, CDK5R1, STRADA, FAM20A, CAB39L, PARP6, TAOK1, IRGM, MTCP1, TCL1A, DBF4B, ETAA1, SPRY2, MAP2K1, PARP8, MLST8, TCL1B, INCENP, DELE1 |
| protein serine/threonine kinase activity | molecular function | AMHR2, TSSK4, TSSK6, AURKC, CDK1, MAPK3, MAPK1, AKT1, GSK3B, ATM, CSNK2A2, MTOR, CSNK2B, BRSK2, PIK3CA, MAPK8, ATR, BMPR2, LMTK2, CDC7, RAF1, MAK, CLK3, CDK9, CAMK4, MAST2, LIMK2, DMPK, MAPK14, CAMK2B, CAMK2D, PDK4, WNK3, TBK1, NRBP1, MOK, CAB39, GRK5, CSNK1A1, STK3, DYRK1A, PDK3, NEK8, STK36, PLK2, MAP3K4, EEF2K, DYRK3, KALRN, MARK3, CDK7, MAP4K2, MAPK6, NEK1, RPS6KB2, CIT, CPNE3, CDK14, ACVR1B, STK4, MAPK11, MARK2, ADCK2, MAP4K1, WNK4, STK31, DYRK1B, MAP3K7, RPS6KB1, PRKCH, MAPK4, CSNK1E, IRAK1, TLK2, UHMK1, ALPK1, PASK, EIF2AK1, MAP3K20, STK17A, RPS6KL1, STK25, IRAK2, BUB1, BUB1B, STK17B, PRKACB, ACVR1, PRKD1, STK38, CAMK1D, MASTL, CDK15, ROCK2, BCR, BRAF, GRK4, BMPR1A, SYK, CLK2, HIPK1, MAPKAPK5, NEK11, SRPK1, STRADB, MAP3K8, PRKX, SRPK2, ALPK2, CDKL3, HIPK4, TAOK2, DCAF1, STK10, NEK3, ACVR2B, FASTK, MAP3K15, MAP4K3, MYO3B, RPS6KC1, MKNK2, SGK2, BMP2K, MAP3K6, MAP4K4, PRKCQ, IKBKE, CDKL4, NEK10, VRK2, ULK2, STK35, RIOK1, WNK1, STK38L, IRAK3, GRK2, MAP2K4, MAP2K3, CSNK1D, ROCK1, FAM20C, CAMKK1, TTN, DYRK2, |
| protein serine/threonine kinase inhibitor activity | molecular function | CIB1, INKA2, INKA1, SPRED1, MACROH2A1, SPRY2, RPTOR |
| protein serine/threonine phosphatase activity | molecular function | PTEN, CYCS, CDKN3, ILKAP, PPM1B, PPP2CA, PPP4R1, MTMR6, PPEF2, PPP2R1B, PPA2, MTMR4, PPP6C, PPP1R3D, PHLPP2, PPP3CB, UBLCP1, TAB1, LRRC28, PPP1CB, PPM1L, LRRC8D, PPM1K, PPP1R3C, PPM1J, PPEF1, LRRC8C, TIMM50, PPM1G, CDC14B, PPP3CA, PDP1, PP2D1, PPTC7, PPM1A, DUSP1, PPP5C, PPP4C, MTMR3, LRRC8B, PDP2, PPM1E, PGAM5, CTDNEP1, LCK, PHLPP1, PPP2R1A, PPM1H |
| protein serine/threonine phosphatase inhibitor activity | molecular function | PPP1R2, PPP1R14A, PPP1R14C, PPP1R8, PPP1R1A, FAM122A, PPP1R11, MYOZ1 |
| protein serine/threonine/tyrosine kinase activity | molecular function | AURKC, AKT1, CLK3, DYRK1A, DYRK3, DYRK1B, RPS6KB1, CLK2, ACVR2B, DYRK2, RPS6KA2, MAP2K2, MAPK9, CLK4, SGK1, TTK, CLK1, DSTYK, PRKAA2, RPS6KA1, MAP2K1, TESK2, PRKCG, AURKB |
| protein tag | molecular function | SUMO1, RPS27A, NEDD8, ISG15, UBC, UBA52, UBL5, URM1, UBB |
| protein transmembrane transporter activity | molecular function | AZGP1, SEC63, TOMM22, TOMM70, SEC61G, TOMM7, SEC61A2, SEC61A1, TOMM40 |
| protein transporter activity | molecular function | RAP1A |
| protein transporter activity | molecular function | TIMM9, GPIHBP1, LRP2, TIMM10 |
| protein tyrosine kinase activator activity | molecular function | GAS6, GHRL, NRG1, ERCC6, AFAP1L2, ABI1, ERBB3, GRM5 |
| protein tyrosine kinase activity | molecular function | EGFR, EGF, ERBB2, HSP90AA1, FLT1, FGFR2, FGFR3, TYK2, WEE1, AXL, KDR, FGFR1, IL5, INSR, YES1, IGF1R, KIT, SRC, NRG1, FGF17, CLK3, FGF8, TWF1, NTRK1, FGF3, FGF9, DDR1, RYK, JAK2, DYRK1A, DYRK3, NEK1, ALK, DYRK1B, LTK, BAZ1B, EPHB2, TIE1, PTK2, FLT4, SYK, CLK2, HIPK1, HIPK4, ROS1, ITK, ZAP70, TEK, NTRK2, MAP2K4, MAP2K3, EPHB1, TTN, DYRK2, SRMS, MAP2K7, TEC, EPHA6, HIPK3, JAK1, MAP2K2, HIPK2, TNK1, CLK4, ABL1, FER, TTK, CLK1, LYN, DSTYK, ABL2, EPHA4, SCYL1, EPHA1, MAP2K6, BTK, FGR, EIF2AK2, ERBB3, MAP2K1, AATK, RET, PDGFRB, EPHA2, MAP2K5, EPHA7, HCK, MST1R, LCK, PDGFRA, EPHA3, EPHA8, FGFR4, CSK, FRK, CAMKK2, TESK2, FES, CSF1R, INSRR, MATK, JAK3, EPHB3, EPHB4, ROR2, PTK6, EPHA10, MERTK, PKDCC, PTK2B, TXK, TTBK1, BLK, TYRO3 |
| protein tyrosine kinase binding | molecular function | BANK1, DUSP22, SH2B3, ACVR1, NEDD9, CD247, CBL, DSCAM, EPHA4, TREM2, DUSP3, CLASP2, CD4, CEACAM1, CDH5, CRK, PRR7, PHYHIP, GRM5, TRIM6 |
| protein tyrosine kinase collagen receptor activity | molecular function | DDR1 |
| protein tyrosine kinase inhibitor activity | molecular function | RACK1, CEP43, IBTK |
| protein tyrosine phosphatase activity | molecular function | CDC25A, CDC25C, PTEN, ACP1, PTPN11, DUSP6, PTPRJ, PTPDC1, CDKN3, RNGTT, TPTE, MTM1, DUSP13, DUSP11, PTPRR, MDP1, DUSP22, MTMR6, DUSP8, TNS2, DUSP19, DUSP15, PTPRF, MTMR4, PTPRA, PTPN23, PTPN2, PTPN6, PTP4A1, DUSP21, PTPRG, MTMR8, PTPRT, DUSP14, PTPN20, HACD2, PTPN22, PTPRC, DUSP5, PTPN13, SSH2, PTPRB, PTPN9, TIMM50, CDC14B, PTPRM, PTPMT1, PTPRN2, EYA4, MTMR1, DUSP18, PGP, DUSP28, SSH3, PTPRU, PTPN1, PTPRE, UBASH3B, DNAJC6, DUSP1, MTMR3, PTP4A3, PTPN7, DUSP3, PTPRO, DUSP7, PTPN5, SSH1, EYA1, PTPRS, PTPN14, PTPRZ1, PTPN12, PTPN18, PTPRH, PTPN4, DUSP9, DUSP16, ACP4, DUPD1, PALD1, CDC25B, DUSP26, EYA2, PTPRD, PTPN3, MTMR14, DUSP2, TPTE2, MTMR7, DUSP10 |
| protein tyrosine/serine/threonine phosphatase activity | molecular function | PTEN, DUSP6, SBF1, PTPDC1, CDKN3, RNGTT, TPTE, DUSP13, DUSP11, DUSP22, DUSP8, DUSP19, DUSP15, PTP4A1, DUSP21, DUSP27, DUSP14, DUSP5, SSH2, CDC14B, PTPMT1, DUSP18, DUSP28, SSH3, DUSP1, PTP4A3, DUSP3, DUSP7, SSH1, DUSP9, DUSP16, DUPD1, DUSP26, DUSP2, TPTE2, DUSP10 |
| protein tyrosine/threonine phosphatase activity | molecular function | DUSP8, DUSP5, DUSP1, DUSP16, DUSP2, DUSP10 |
| protein xylosyltransferase activity | molecular function | XYLT2, XYLT1 |
| protein-(glutamine-N5) methyltransferase activity | molecular function | HEMK1 |
| protein-arginine deiminase activity | molecular function | PADI1, PADI2, PADI3, PADI4, PADI6 |
| protein-arginine N-methyltransferase activity | molecular function | PRMT6, FBXO11, CARM1, PRMT2, PRMT8, PRMT1, PRMT3, PRMT7, PRMT9 |
| protein-arginine omega-N asymmetric methyltransferase activity | molecular function | PRMT6, CARM1, PRMT2, PRMT8, PRMT1 |
| protein-arginine omega-N monomethyltransferase activity | molecular function | PRMT6, PRMT8, PRMT1, PRMT7 |
| protein-arginine omega-N symmetric methyltransferase activity | molecular function | NDUFAF7, PRMT7, PRMT9 |
| protein-cysteine S-palmitoyltransferase activity | molecular function | ZDHHC16, ZDHHC8, GOLGA7, ZDHHC5, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC23, GLUL, ZDHHC19, ZDHHC21, ZDHHC11, ZDHHC20, ZDHHC3, ZDHHC2, ZDHHC13, ZDHHC7, ZDHHC24, ZDHHC4, YKT6, ZDHHC22, ZDHHC12, ZDHHC18, ZDHHC1 |
| protein-disulfide reductase (glutathione) activity | molecular function | TXNDC12 |
| protein-disulfide reductase activity | molecular function | NXN, TXNDC17 |
| protein-fructosamine 3-kinase activity | molecular function | FN3K |
| protein-glucosylgalactosylhydroxylysine glucosidase activity | molecular function | PGGHG |
| protein-glutamic acid ligase activity | molecular function | TTLL6, TTLL4 |
| protein-glutamine gamma-glutamyltransferase activity | molecular function | EPB42, TGM1, TGM5, TGM7, TGM4, TGM2, TGM6, TGM3 |
| protein-glutamine N-methyltransferase activity | molecular function | N6AMT1 |
| protein-glutaryllysine deglutarylase activity | molecular function | SIRT5, SIRT7 |
| protein-glycine ligase activity, initiating | molecular function | TTLL3 |
| protein-histidine N-methyltransferase activity | molecular function | SETD3, METTL18 |
| protein-hormone receptor activity | molecular function | LHCGR, FSHR, RXFP2, GNRHR, LGR4, TSHR, LGR5, LGR6 |
| protein-L-isoaspartate (D-aspartate) O-methyltransferase activity | molecular function | PCMT1, PCMTD1, PCMTD2 |
| protein-lysine 6-oxidase activity | molecular function | LOXL2, LOX, LOXL3 |
| protein-lysine N-methyltransferase activity | molecular function | EZH2, SETD3, SETD4, METTL21C, EEF1AKMT1, METTL21A, EHMT2, ATPSCKMT, SETD6, EHMT1, EEF2KMT, ANTKMT, SETD7, EEF1AKMT3, METTL22, VCPKMT, ETFBKMT, FAM86C1, EEF1AKMT2, EEF1AKMT4, SMYD2, KMT5A |
| protein-malonyllysine demalonylase activity | molecular function | SIRT5 |
| protein-N-terminal asparagine amidohydrolase activity | molecular function | NTAQ1, NTAN1 |
| protein-N-terminal glutamine amidohydrolase activity | molecular function | NTAQ1 |
| protein-propionyllysine depropionylase activity | molecular function | SIRT7 |
| protein-ribulosamine 3-kinase activity | molecular function | FN3KRP, FN3K |
| protein-succinyllysine desuccinylase activity | molecular function | SIRT5, SIRT7 |
| protein-tyrosine sulfotransferase activity | molecular function | TPST1 |
| proteinase activated receptor binding | molecular function | BICD1, PDCD6IP |
| proteoglycan binding | molecular function | CECR1, CTSK, CTSL, CTSB, PTN, COL2A1, THBS1, CTSS, COL5A1, COL5A3, COMP, SLIT2 |
| proteoglycan sulfotransferase activity | molecular function | GAL3ST3, GAL3ST4 |
| protoheme IX farnesyltransferase activity | molecular function | COX10 |
| proton-dependent oligopeptide secondary active transmembrane transporter activity | molecular function | CDH17, SLC15A1 |
| proton-exporting ATPase activity, phosphorylative mechanism | molecular function | ATP2A2, ATP6V1G1, ATP6V1E1, ATP6V1G2, ATP2C1, ATP6V1G3, ATP6V1C1, ATP6V0D1, ATP2A3, ATP6V1E2, ATP2A1, ATP2C2, ATP6V1C2 |
| proton-transporting ATP synthase activity, rotational mechanism | molecular function | ATP5F1C, ATP5PO, ATP5F1B, ATP5PB, ATP5MC3, ATP5PF, ATP5F1E, ATP5PD, ATP5MC1, ATP5F1D, ATP5MC2, ATP5MG, ATP5MF, ATP5ME, ATP6V0C |
| proton-transporting ATPase activity, rotational mechanism | molecular function | ATP6V0A2, ATP6V1D, ATP5F1B, ATP6V1B2, ATP6V1E1, ATP6V0E1, ATP6V1A, ATP6V0E2, ATP6V1C1, ATP6V1H, ATP6V0D1, ATP6V0B, ATP6V0A4, ATP6V1F, TCIRG1, ATP6V1E2, ATP6V0C, ATP6V1C2, ATP6V0A1 |
| pseudouridine 5'-phosphatase activity | molecular function | PUDP |
| pseudouridine synthase activity | molecular function | DKC1, RPUSD4, RPUSD3, TRUB1, PUSL1, PUS10, PUS3, PUS7L, RPUSD1, TRUB2, PUS7 |
| PTB domain binding | molecular function | APP, INSR, NUP62 |
| purine nucleobase binding | molecular function | PNP, PYGL |
| purine nucleobase transmembrane transporter activity | molecular function | SLC28A2, SLC28A1, AQP9, SLC28A3 |
| purine nucleoside binding | molecular function | OARD1, ADA |
| purine nucleoside transmembrane transporter activity | molecular function | SLC28A2, SLC29A2, SLC29A1 |
| purine nucleotide binding | molecular function | PCK2, RRM1, FAM114A2, RENBP, POLA1 |
| purine nucleotide transmembrane transporter activity | molecular function | ABCC11 |
| purine ribonucleoside triphosphate binding | molecular function | PSMA6 |
| purine ribonucleotide binding | molecular function | UCP1 |
| purine-nucleoside phosphorylase activity | molecular function | LACC1, PNP, MTAP |
| purine-rich negative regulatory element binding | molecular function | PURA, ELK3, PURG, PURB |
| purine-specific mismatch base pair DNA N-glycosylase activity | molecular function | PCNA, MUTYH |
| purine-specific nucleoside:sodium symporter activity | molecular function | SLC28A3 |
| purinergic nucleotide receptor activity | molecular function | P2RX7, P2RX6, P2RX4, P2RX5, P2RX3, P2RX2 |
| putrescine binding | molecular function | AMD1 |
| putrescine transmembrane transporter activity | molecular function | OAZ3 |
| pyridine N-methyltransferase activity | molecular function | NNMT |
| pyridoxal binding | molecular function | GLDC |
| pyridoxal kinase activity | molecular function | PDXK |
| pyridoxal phosphatase activity | molecular function | PHOSPHO2, PDXP |
| pyridoxal phosphate binding | molecular function | ALB, CBS, PDXK, CSAD, GLDC, SHMT1, KYNU, PDXDC1, GOT1L1, DDC, MOCOS, SDSL, GPT, MTARC2, GAD1, SHMT2, SPTLC3, GOT1, GADL1, GPT2, PLPBP, OAT, PHYKPL, CTH, SPTLC1, ABAT, NFS1, GCAT, AGXT, PYGL, PYGB, KYAT1, SPTLC2, TAT, AADAT, ACCS, THNSL2, GOT2, SDS, SRR, ALAS1, PYGM, GAD2, PNPO, MTARC1 |
| pyridoxamine-phosphate oxidase activity | molecular function | PNPO |
| pyrimidine deoxyribonucleotide binding | molecular function | DCTPP1 |
| pyrimidine nucleobase transmembrane transporter activity | molecular function | AQP9 |
| pyrimidine nucleotide binding | molecular function | NT5C, POLA1 |
| pyrimidine nucleotide transmembrane transporter activity | molecular function | SLC25A33, SLC25A36 |
| pyrimidine nucleotide-sugar transmembrane transporter activity | molecular function | SLC35A1, SLC35D1, SLC35D2, SLC35A5, SLC35A3, SLC35A4, SLC35E4, SLC35A2 |
| pyrimidine ribonucleotide binding | molecular function | UGP2 |
| pyrimidine- and adenine-specific:sodium symporter activity | molecular function | SLC28A2, SLC28A1, SLC28A3 |
| pyrimidine-nucleoside phosphorylase activity | molecular function | TYMP |
| pyrimidine-specific mismatch base pair DNA N-glycosylase activity | molecular function | TDG, MBD4 |
| Pyrin domain binding | molecular function | PYCARD, NLRP2 |
| pyroglutamyl-peptidase activity | molecular function | PGPEP1 |
| pyrophosphatase activity | molecular function | GMPS, DCTPP1, PHOSPHO1, PPA1, PRUNE2, PRUNE1, ALPL |
| pyrroline-5-carboxylate reductase activity | molecular function | PYCR2, PYCR1, PYCR3 |
| pyruvate carboxylase activity | molecular function | PC |
| pyruvate dehydrogenase (acetyl-transferring) activity | molecular function | PDHA1, PDHB |
| pyruvate dehydrogenase (acetyl-transferring) kinase activity | molecular function | PDK4, PDK3, PDK1, PDK2 |
| pyruvate dehydrogenase (NAD+) activity | molecular function | PDHA1, PDHX, PDHB, DLAT |
| pyruvate dehydrogenase activity | molecular function | PDHA1 |
| pyruvate kinase activity | molecular function | PKM, PKLR |
| pyruvate secondary active transmembrane transporter activity | molecular function | SLC16A7 |
| pyruvate transmembrane transporter activity | molecular function | SLC16A7, MPC1, MPC2, MPC1L, SLC16A11 |
| quaternary ammonium group transmembrane transporter activity | molecular function | SLC22A5, SLC22A4, SLC22A1, SLC22A3 |
| quercetin 2,3-dioxygenase activity | molecular function | PIR |
| quinone binding | molecular function | ETFDH, AOC2, TP53I3, NDUFS2, CBR4, HSD17B8, AOC1, VKORC1L1, SQOR, AOC3, NDUFS7, VKORC1 |
| R-SMAD binding | molecular function | ZEB2, PARP1, SMAD4, PMEPA1, MEN1, SMAD6, RANBP3, PPM1A, SMAD2, MYOCD, RGCC, TRIM33, FOS, ZC3H3, LDLRAD4, SMAD3, FOXH1, ANKRD1 |
| Rab GDP-dissociation inhibitor activity | molecular function | GDI2, GDI1 |
| Rab geranylgeranyltransferase activity | molecular function | FNTA, RABGGTB |
| Rab GTPase binding | molecular function | ODF2, ANXA2, MYRIP, ACAP2, RAB11FIP2, TBC1D15, OPTN, EVI5, USP6NL, RIMS2, AP3M1, RAB29, VPS52, ALS2, RAB11FIP5, GDI2, C9orf72, PDE6D, NSF, RIMS1, DENND1C, TBCK, ANKRD27, AP1G1, CHML, RABGGTB, TBC1D1, RAB11FIP4, EXPH5, RABGAP1, DENND1A, SYTL4, BICD1, PICALM, STXBP5, TBC1D20, ANKFY1, RABGEF1, TBC1D30, MYO5A, ANXA9, DENND5A, TBC1D10C, DMXL2, KIF16B, HPS4, TBC1D22B, ADPRH, TBC1D13, TMEM127, ULK1, MICAL3, TBC1D3D, TBC1D3I, TBC1D3E, TBC1D3F, TBC1D3L, LLGL1, SYTL3, DENND1B, TBC1D26, ERC1, NPC1L1, TBC1D4, RHOBTB3, TBC1D8, RAC1, ARHGAP1, RAB11FIP1, TBC1D22A, UNC13B, TBC1D12, TBC1D28, TBC1D10B, HACE1, BICD2, RAB3GAP2, SYTL2, RABGAP1L, MYO5B, SGSM2, RIC1, TBC1D9, PIFO, RGP1, TBC1D9B, YIPF2, LLGL2, RILP, ATP6AP1, UNC13D, TBC1D16, NDRG1, EVI5L, RPH3A, GAS8, GOLGA5, TBC1D5, YIPF1, NGFR, RAB8A, RAB3GAP1, BICDL1, SYTL1, RIMS3, GRTP1, MICAL1, TBC1D7, CLEC16A, SGSM3, TBC1D2, RAB11FIP3, USP6, TBC1D25, MICALL2, RUSC2, MICALL1, RIN3, TBC1D17, RPH3AL, TBC1D14, STXBP5L, MOBP, RIMS4, GDI1 |
| Rab guanyl-nucleotide exchange factor activity | molecular function | SBF1, RIN2, DENND2A, ALS2, RAB3IP, C9orf72, DENND4A, DENND1C, DENND6A, DENND1A, DENND2D, RABGEF1, DENND5A, WDR41, DENND1B, SBF2, DENND6B, SH3BP5, DENND4C, RAB3GAP2, RIC1, SMCR8, RGP1, RAB3IL1, MADD, RAB3GAP1, DENND3, DENND4B, SH3BP5L, RIN3, DENND5B |
| Rac GTPase binding | molecular function | SOD1, MTSS2, NOX1, IQGAP1, IQGAP2, ALS2, NCKAP1, GARRE1, SRGAP3, RALBP1, CORO1C, DVL1, OCRL, IQGAP3, ABI2, NOXA1, RCC2, ARHGAP17, CYFIP2, SRGAP2, SRGAP2C, EPS8, TIAM1, DOCK7, CDKL5, ELMO2, DVL2, CYFIP1, HACE1, ARHGEF2, ATP7A, ARHGDIB, WASF1, ELMO3, ARHGDIG, NCKAP1L, DVL3, WAS, ARHGAP4, PKN1, ITPKA, SH3BP1, SRGAP1, ARHGAP44, ELMO1, FMNL1, DOCK4, CAV1, CYRIA |
| Rac guanyl-nucleotide exchange factor activity | molecular function | ALS2, VAV3, PREX2, ARHGEF4, FRMD7, EPS8, TIAM1, FARP1, SPATA13, ECT2, DOCK3, ARHGEF2, FARP2, PREX1, VAV1, EPS8L1, TIAM2, DOCK2, DOCK4 |
| racemase and epimerase activity | molecular function | DHRS9 |
| racemase and epimerase activity, acting on carbohydrates and derivatives | molecular function | FUOM, GLCE, RPE |
| raffinose alpha-galactosidase activity | molecular function | GLA |
| RAGE receptor binding | molecular function | S100A12, FPR1, S100A9, S100A4, HMGB1, S100A8, S100P, S100A7, S100B, S100A13 |
| Ral GTPase binding | molecular function | RALBP1, RNF41, USP33, EXOC5, EXOC8, PIH1D2, EXOC4, LSM2, MYO1C, RAB34, EXOC2 |
| Ral guanyl-nucleotide exchange factor activity | molecular function | RALGPS1, RGL1, RGL3 |
| Ran GTPase binding | molecular function | BIRC5, RANGAP1, RGPD4, IPO11, XPO1, IPO9, IPO4, IPO8, RANGRF, IPO5, SPRYD3, TNPO3, NXT1, XPOT, TNPO1, XPO7, CSE1L, RANBP3, MYCBP2, IPO7, RGPD2, XPO6, RANBP2, RCC1, RANBP3L, IPO13, NUTF2, TNPO2, RGPD1, RANBP10, RGPD8, RGPD5 |
| Ran guanyl-nucleotide exchange factor activity | molecular function | RANGRF, SERGEF, RCBTB2, RCC1 |
| Rap guanyl-nucleotide exchange factor activity | molecular function | RAP1A, RAPGEF2, RAPGEF1, RAPGEF3 |
| Ras GTPase binding | molecular function | CIB1, RAP1A, SPHK2, SH3BP4, IQGAP1, IQGAP2, RASGRP3, IQGAP3, RAPGEF6, DGKI, LZTR1, RASSF5, RIN1, PLCE1, MAPKAP1, TIAM1, RGL3, RAP1GAP, AFDN, RAPGEF4 |
| Ras guanyl-nucleotide exchange factor activity | molecular function | EGFR, EGF, KITLG, ERBB2, FGFR2, FGFR3, FGFR1, IL2RA, IL5, KIT, GFRA1, IL2, NRG1, FGF17, NCAM1, FGF8, SOS1, FGF3, FGF9, GDNF, RASGRP3, RAPGEF2, RASGRP1, RASGRP4, RGL2, RASGRF2, KNDC1, RASGEF1A, ADRB1, RASGRF1, RAPGEF4 |
| rDNA binding | molecular function | TSPYL2, MACROH2A1, DHX33 |
| receptor activator activity | molecular function | IGF2, ANXA2, PRKCE |
| receptor activity | molecular function | ICAM1, FAS, AMHR2, TLR4, TLR2, KRT1, ITGB1, PLAUR, IGSF1, IGF2R, CD46, FPR1, GFRA1, TNFRSF25 |
| receptor agonist activity | molecular function | VEGFA, GAS6, NODAL, WNT10A, CCL11, WNT7B, GPNMB, TAFA4, WNT4, IL17D, WNT9B, WNT3A, NTS, WNT8B, TAC4, GREM2, CCL26, LRPAP1, TAFA2, SFRP2, WNT10B, TAFA3, WNT9A, NBL1, WNT3, WNT7A, AGT, GREM1, ZP3 |
| receptor antagonist activity | molecular function | ESR2, DKK1, SPINT3, LRPAP1, WFIKKN2, DKK4, IL18BP, WFIKKN1, DKK2 |
| receptor binding | molecular function | LHB, IL1B, AMH, IL6, PGR, INHBA, AR, LIF, BDNF, ADM, NRIP1, TNFSF10, INSL3, HSD17B4, HLA-B, SERPINE1, HLA-E, FASLG, GAS6, C3, APP, ITGB1, LEP, CSNK2B, PLAUR, HFE, PARK7, IL1RAPL1, GSTK1, A2M, CAT, YES1, SRC, MIF, HLA-G, NOS2, GFRA1, NRG1, NCOA2, IZUMO1, TAC3, FGF17, IDH1, PLAT, NGF, HSPA1A, HSPA1B, GJA1, F2R, EPHX2, FGF8, PICK1, INHA, FGF3, FGF9, GBA, DAO, TAC1, GDNF, CX3CL1, IAPP, RASA1, BEX3, FGL1, ERBIN, TRIM24, TRAK2, JAK2, TNFSF15, SCP2, SRI, BANK1, TESPA1, DIAPH2, GLA, STRAP, UTS2, LPL, TDGF1, NRG3, GRIN1, FZD8, BEX1, AMACR, NXPH3, LGI1, IGFBP1, NCK1, ASIP, RACK1, SLC9A3R1, GIPC1, TNFSF12, PLXNC1, CD58, EFNA1, EPHB2, PSMC5, TRDN, ABCA12, EGFL8, WNT10A, TRAF3IP2, CTNND1, ANXA1, GUSB, F7, WNT7B, NRXN1, LTB, PIK3AP1, NRG4, PPARGC1A, C5, FGG, GRP, NTF4, WNT4, ADIPOQ, SMARCD3, RAB8B, SEMA3G, WNT9B, SRPX2, NPY, CNTFR, ARPP19, WNT3A, LAMA4, IGFL2, HJV, SEMA4D, UFD1, PANX1, CYTL1, IL20, STOML2, CRH, PKD2, APOF, MOG, IFNL1, BTN3A1, MTSS1, DIAPH1, FCN3, NMU, WNT2B, WNT8B, SRMS, LRRC4B, TRAK1, ANGPTL3, LRP6, FGB, |
| receptor inhibitor activity | molecular function | PCSK9 |
| receptor regulator activity | molecular function | MRAP2 |
| receptor serine/threonine kinase binding | molecular function | FADD, OPRD1, GPR17 |
| receptor signaling protein tyrosine kinase activator activity | molecular function | CCL5, ALKAL2, ALKAL1 |
| receptor signaling protein tyrosine kinase inhibitor activity | molecular function | HYAL2 |
| receptor tyrosine kinase binding | molecular function | TP53, GAS6, NRG1, PCNA, PTPN11, ANXA5, FNTA, CPNE3, SHC1, NRG3, MAP3K7, SOCS5, NCK1, RACK1, EIF3A, RNF41, STAP1, PTPN2, PITPNM3, SQSTM1, DAZAP2, ANGPT4, ANGPT1, TIAM1, ZPR1, SHC4, ELMO2, CBL, ALKAL2, FIZ1, ANGPT2, MST1, TOB1, PITPNM1, PTPN1, CD2, ITGAX, HYAL2, DUSP3, YWHAG, ALKAL1, NRTN, CBLB, PITPNM2, PSPN, PTPN14, PIK3R2, ACP4, CBLC, LRP4, SHC2, ARHGEF16, SHC3, FLT3LG, DOCK4, MYOC |
| receptor-receptor interaction | molecular function | FGF20, FGF2 |
| recombinase activity | molecular function | DMC1 |
| reduced folate carrier activity | molecular function | SLC19A1 |
| reelin receptor activity | molecular function | VLDLR |
| regulatory region DNA binding | molecular function | EZH2 |
| regulatory region RNA binding | molecular function | MBNL1 |
| repressing transcription factor binding | molecular function | CTNNB1, PARK7, MYC, HDAC4, SRI, TLE1, ZNF503, MAGEA2, HDAC9, SKI, RELA, HMGB1, DDX20, EIF4E, TLE4, KAT5, RBPJ, HDAC7, CTBP1, NFYB, TLE2, RUNX2, ZNF703, PRDM5, ZMYND8, ARNTL, TLE5, CBX5, HHEX, HDAC5, NOC2L, TLE3, TLE6 |
| resveratrol binding | molecular function | NQO2 |
| retinal binding | molecular function | ALDH1A2, RBP5, RBP1, RBP2, RBP7, RLBP1, CRABP1, RBP4, CRABP2, STRA6, RBP3 |
| retinal dehydrogenase activity | molecular function | AKR1C3, ALDH1A2, AKR1B1, AKR1B10, ALDH1A3, ALDH1A1, ALDH8A1, AKR1C4 |
| retinal isomerase activity | molecular function | BCO2, BCO1, RPE65 |
| retinoic acid 4-hydroxylase activity | molecular function | CYP26B1, CYP2C8, CYP26A1, CYP3A5, CYP2C18, CYP26C1, CYP2S1, CYP2W1 |
| retinoic acid binding | molecular function | SERPINA5, IGF2R, NR2F2, CYP26B1, UGT2B7, UGT1A8, FABP5, UGT1A4, CYP26A1, UGT2B15, UGT2B4, UGT2B17, CRABP1, LCN12, CYP26C1, CRABP2, CYP2W1, UGT1A9, UGT1A6, UGT1A3, UGT1A7, UGT1A10, RARA |
| retinoic acid receptor binding | molecular function | NRIP1, NCOA2, CNOT1, NSD1, ASXL1, TACC1, CTBP2, PRMT2, PRAME, MED25, NCOA1, NCOR2, SNW1, LRIF1, ACTN4 |
| retinoic acid-responsive element binding | molecular function | ZNF536, NR2F1, RXRG, RARA |
| retinoid binding | molecular function | PTGDS, RBP5, RBP1, RBP2, RBP7, CRABP1, RBP4, CRABP2, RBP3 |
| retinoid X receptor binding | molecular function | VDR, NRIP1, NCOA2, PPARG, FUS, NSD1, RARB, NCOA6, TACC1, NR4A2, MED25, NR1H4, NCOA1, NCOR2, ARID5A, RARG, NR1H2 |
| retinol binding | molecular function | ADH4, RBP5, RBP1, RBP2, RBP7, RLBP1, CRABP1, RBP4, CRABP2, STRA6, C8G, RBP3 |
| retinol dehydrogenase activity | molecular function | AKR1C3, ADH4, DHRS3, AKR1A1, DHRS9, ADH1A, ADH6, HSD17B6, ADH1B, RDH10, RDH11, BMP2, RDH5, RDH12, RDH8 |
| retinol isomerase activity | molecular function | DEGS1, RPE65 |
| retinol O-fatty-acyltransferase activity | molecular function | DGAT2, DGAT1 |
| retinol transmembrane transporter activity | molecular function | RBP4, STRA6 |
| retinyl-palmitate esterase activity | molecular function | PNPLA4, PLB1 |
| retromer complex binding | molecular function | M6PR, RAB7A, SORT1, TBC1D5, WASHC2C |
| Rho GDP-dissociation inhibitor activity | molecular function | ARHGDIA, ARHGDIB, ARHGDIG |
| Rho GDP-dissociation inhibitor binding | molecular function | HSP90AA1, CDC42, RAC1, PLXNB3 |
| Rho GTPase binding | molecular function | KIF3B, YBX3, DIAPH2, IQGAP1, IQGAP2, IQGAP3, ROCK2, INF2, DIAPH1, ROCK1, DOCK11, SIKE1, STRN3, ECT2, CDC42SE2, ARHGEF2, FMNL2, AKAP13, PARD6A, PARD6B, CDC42BPB, PAK3, DAAM2, RTKN, CDC42SE1, RHOH, MYO9B, ARHGEF16, KIAA1614, PARD6G, FMNL1, LRRK2, DIAPH3, FMNL3 |
| Rho guanyl-nucleotide exchange factor activity | molecular function | SOS1, ARHGEF3, ARHGEF10, KALRN, ARHGEF11, VAV3, MCF2, BCR, ARHGEF6, ARHGEF5, ARHGEF12, DOCK11, PLEKHG3, TIAM1, FGD6, ARHGEF28, FARP1, PLEKHG2, ECT2, ARHGEF10L, ARHGEF2, AKAP13, DOCK1, ARHGEF37, TRIO, RGL2, ARHGEF1, FGD4, MCF2L, NGEF, ARHGEF17, FARP2, FGD2, PREX1, ARHGEF25, VAV1, PLEKHG5, ARHGEF16, ARHGEF18, EPS8L1, NET1, FGD5, ARHGEF26, PLEKHG1 |
| Rho-dependent protein serine/threonine kinase activity | molecular function | ROCK2, ROCK1 |
| rhodopsin kinase activity | molecular function | GRK4, GRK7, GRK1 |
| ribitol 2-dehydrogenase activity | molecular function | SORD |
| ribitol beta-1,4-xylosyltransferase activity | molecular function | RXYLT1 |
| riboflavin kinase activity | molecular function | RFK |
| riboflavin reductase (NADPH) activity | molecular function | BLVRB |
| riboflavin transmembrane transporter activity | molecular function | SLC52A3, SLC52A2, SLC52A1, ABCG2 |
| ribokinase activity | molecular function | RBKS |
| ribonuclease A activity | molecular function | RNASE4, RNASE2 |
| ribonuclease activity | molecular function | AZGP1, RNASET2, POP4, RPP14, ZC3H12A, RNASE11, RNASE4, HELZ2, RNASE2, RNASEL, ERN1, DIS3, SAMHD1, RNASE6, RNASE3, POP5, RNASEH2A, DIS3L, ANG, ERN2, DIS3L2, RNASEH1, RNASE7 |
| ribonuclease E activity | molecular function | PPP1R8 |
| ribonuclease III activity | molecular function | DROSHA, DICER1, MRPL44 |
| ribonuclease inhibitor activity | molecular function | RNH1 |
| ribonuclease P RNA binding | molecular function | POP4, RPP14, RPP38, POP1, RPP25, POP5, RPP21, POP7 |
| ribonuclease T2 activity | molecular function | RNASET2 |
| ribonucleoprotein complex binding | molecular function | EZH2, HNRNPU, ITCH, IFIH1, UHMK1, PHF6, PRPF6, RPLP1, PRPF31, WDR12, RNASEL, RNF135, CD2BP2, SMG6, GEMIN4, TIMM50, SRP54, SECISBP2L, CKAP5, PPIH, PQBP1, PES1, CBX5, SECISBP2, EIF4A3, EEFSEC, APOBEC1, PRMT7, PITX2 |
| ribonucleoside binding | molecular function | POLR1B, POLR2B, POLR3B |
| ribonucleoside-diphosphate reductase activity | molecular function | RRM1 |
| ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor | molecular function | RRM2, RRM2B, RRM1 |
| ribose phosphate diphosphokinase activity | molecular function | PRPS2, PRPS1L1, PRPS1, PRPSAP1, PRPSAP2 |
| ribose-5-phosphate isomerase activity | molecular function | RPIA |
| ribosomal large subunit binding | molecular function | NPM1, LTN1, NEMF, RBM3, MRRF, OLA1, CPEB2, MALSU1, EIF6, ZNF593, CPSF6, DHX33 |
| ribosomal protein S6 kinase activity | molecular function | RPS6KB2, RPS6KB1, RPS6KA2, RPS6KA1, RPS6KA4 |
| ribosomal small subunit binding | molecular function | DDX3X, NPM1, PTCD3, EIF1, ERAL1, DHX29, MTIF3, CPEB2, LARP1, EIF1B, NME1, UNG |
| ribosome binding | molecular function | FMR1, MTOR, BAG6, HSPA5, ETF1, YTHDF1, EIF3K, ZC3H12A, LETMD1, MAIP1, SBDS, SRP19, YTHDF3, EIF2A, RPN2, RACK1, EIF5A, EIF5A2, MTRF1L, MTRF1, PELO, NAA16, GCN1, OLA1, EEF2, EFL1, PYM1, MTIF3, CPEB4, ERI1, GUF1, GEMIN5, EIF3C, CPEB1, SHFL, EIF2S1, CPEB2, NAA15, SRP72, LETM2, CPEB3, SEC61A2, RPSA, EIF6, ABCF1, NAA10, SEC61A1, IMPACT, LETM1, PRMT3, IGHMBP2, ZNF598, GTPBP6 |
| ribosylnicotinamide kinase activity | molecular function | NMRK1, NMRK2 |
| ribosylnicotinate kinase activity | molecular function | NMRK1, NMRK2 |
| ribulose-phosphate 3-epimerase activity | molecular function | RPE |
| RIG-I binding | molecular function | TRIM25, SEC14L1, RNF135 |
| RING-like zinc finger domain binding | molecular function | UBE2I, BMI1, MAFK, RNF2 |
| RISC complex binding | molecular function | SND1 |
| RNA 2'-O-methyltransferase activity | molecular function | FTSJ3 |
| RNA 5'-methyltransferase activity | molecular function | MEPCE |
| RNA 7-methylguanosine cap binding | molecular function | NCBP2, NCBP1, GEMIN5, CYFIP2, EIF4E, EIF4E2, CYFIP1, AGO2, NCBP3, LARP1, EIF4E3, DCPS |
| RNA adenylyltransferase activity | molecular function | TENT5C, TENT5A, TENT5D, TENT5B |
| RNA binding | molecular function | DDX3Y, WT1, BRCA1, FMR1, DAZ2, DAZ4, DAZ1, TERT, DNMT1, NR0B1, SNRPN, EZH2, NR3C1, ENO1, PIWIL2, DAZL, PIWIL1, PARK7, PABPC1, NANOS2, KHDRBS1, PABPC1L, LIN28B, NSUN7, PUM2, PABPC3, DAZ3, RBMY1A1, APEX1, NANOS1, DROSHA, DDX25, DICER1, ANXA2, HNRNPL, SRSF4, SRSF9, SRSF6, PIWIL4, BOLL, SIN3A, MOV10L1, RBMX2, RNASET2, RBMX, AGFG1, NANOS3, EXOSC10, PIWIL3, TEP1, ADAT1, NXF2, YBX2, TCERG1, EIF3H, RBFOX2, SYNJ1, USO1, MRPS14, HNRNPCL1, ZC3H11A, ZRANB2, NSA2, POP4, LTA4H, RO60, H1-4, HSPA8, CSTF2, FUS, ATP5F1C, RPL4, RPL3, EIF2D, MATR3, RPL5, RPS10, ARCN1, SRP9, CCT4, DAP3, HNRNPF, CLNS1A, PCBP4, EIF3E, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, EEF1A1, MRPS15, RPL24, HNRNPU, EWSR1, RPL6, HNRNPA0, LBR, PAN3, IBA57, CFAP65, TDRD7, PPIL4, DDX1, GTF3A, GFM1, SPEN, LLPH, MRPL20, GTPBP4, PAIP1, TUT1, RPF1, UPF2, SPATS2L, MRPL22, BCCIP, CPSF2, RSL24D1, MKRN1, MCTS1, RTRAF, CCDC9, NUDT4B, DDX3X, EIF1AY, LSM1, EIF3D, NUDT21, DKC1, KIN, RPP14, UBR5, RPLP0, NPM1, SNRNP70, MRPL3, GSPT1, YBX3, BTF3, PPIB, PSMA1, CANX, RPL29, |
| RNA cap binding | molecular function | LSM1, NCBP2, EIF4A1, NCBP1, EIF4E, EIF4E2, NCBP3, LARP1, SNUPN |
| RNA guanylyltransferase activity | molecular function | RNGTT |
| RNA helicase activity | molecular function | DDX1, DDX3X, G3BP1, DHX40, IFIH1, DDX47, DDX43, DDX19B, EIF4A2, DDX46, SUPV3L1, DHX36, MTREX, DDX39B, DHX32, DDX55, DDX23, DDX10, DDX31, DDX21, DDX52, EIF4A1, HELZ2, DDX24, UPF1, DHX58, DDX50, DHX15, DHX29, DDX41, DDX20, DDX39A, AQR, DDX6, TDRD12, DDX49, DDX60L, DDX53, DDX18, DHX57, DHX30, DDX17, SNRNP200, MOV10, DDX42, DDX60, BRIP1, DHX16, DHX37, SKIV2L, DDX56, DDX51, DHX33, EIF4A3, DHX34, DDX54, IGHMBP2, DHX35, RAD54B, DDX27, DDX3Y, DDX19A |
| RNA lariat debranching enzyme activator activity | molecular function | CWF19L1 |
| RNA lariat debranching enzyme activity | molecular function | DBR1 |
| RNA ligase (ATP) activity | molecular function | RTCB |
| RNA ligase activity | molecular function | RTCB |
| RNA methyltransferase activity | molecular function | TRMT2A, HENMT1, FTSJ1, MEPCE, TGS1, MRM3, FTSJ3, METTL4 |
| RNA N1-methyladenosine dioxygenase activity | molecular function | ALKBH3 |
| RNA N6-methyladenosine dioxygenase activity | molecular function | ALKBH5 |
| RNA NAD-cap (NAD-forming) hydrolase activity | molecular function | DXO |
| RNA NAD-cap (NMN-forming) hydrolase activity | molecular function | NUDT12 |
| RNA polymerase binding | molecular function | TCERG1, PPIB, ANP32B, CCNT1, ERCC6, STOM, NEDD4, PHRF1, PKN2, GSG1, RRN3, ZFP36, TAF10, PABPN1, BIN1, TCERG1L |
| RNA polymerase core enzyme binding | molecular function | SCAF8 |
| RNA polymerase I cis-regulatory region sequence-specific DNA binding | molecular function | UBTF |
| RNA polymerase I core binding | molecular function | ERBB2, SPTY2D1, RRN3, TCOF1 |
| RNA polymerase I core promoter sequence-specific DNA binding | molecular function | SMARCA4, UBTF, TAF1C, TAF1B, SMARCB1, BAZ2A, RRN3 |
| RNA polymerase I general transcription initiation factor activity | molecular function | UBTF, TAF1C, TAF1, RRN3 |
| RNA polymerase I general transcription initiation factor binding | molecular function | POLR1E |
| RNA polymerase II activating transcription factor binding | molecular function | NFE2L2, CTNNB1, RB1, SIN3A, RBL1, RBL2, SETD3, ISL1, TBX10, EXOSC9, BEX1, EOMES, CREBBP, BHLHE40, TBR1, NHLH2, NEUROD1, EP300, TBX5, HIPK2, EGR2, IFI27, MAD2L2, ATF2, TP53BP1, MGA, HEY2, TBX3, NCOR1, FOS, LMO2, LDB1, TBX20, HNF4A, ID2, TBX21, MYOD1, LDB2, TBX6, TBX19, DUSP26, SMAD3, ZFPM1, TBX2, TBX15, PITX2, BHLHE41 |
| RNA polymerase II activity | molecular function | POLR2J, POLR2A |
| RNA polymerase II C-terminal domain binding | molecular function | HNRNPU, SCAF1, PCIF1 |
| RNA polymerase II C-terminal domain phosphoserine binding | molecular function | RTF1, SCAF4, SCAF8, LEO1 |
| RNA polymerase II carboxy-terminal domain kinase activity | molecular function | CDK1, ERCC2, MAPK1, CDK9, GTF2H3, CDK7, CCNH, CDK13, CCNK, GTF2H1, CDK19, GTF2H4, CDK12 |
| RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending | molecular function | CEBPG |
| RNA polymerase II complex binding | molecular function | SUPT4H1, HNRNPU, WAC, RTRAF, RPRD2, ELP2, PCF11, RECQL5, PAF1, ELP4, NCOA3, GTF2B, UVSSA, ERCC5, CTR9, CDC73, URI1, CCAR2, ELOF1, AGO2, SCAF8, RPRD1A, ZNF326, AGO1, RPRD1B, ESRRB, GTF2E1, SMYD2 |
| RNA polymerase II complex recruiting activity | molecular function | GTF2B |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | molecular function | NR5A2, ESR1, PGR, AR, ATF3, SOX10, SP1, STAT1, HSF1, CTCFL, ARNT2, MBD2, MTA2, NR3C1, STAT3, MUC1, NCOA2, EBF2, OTX1, ACTB, MEF2A, ZNF331, CHD7, CLOCK, TCF7L2, MYC, PATZ1, ETV2, HOXA3, EED, GLI3, SKIL, HOXD13, TCF7, HDAC4, HNRNPU, IKZF1, NR1D2, BCL11A, FOXJ3, KLF4, YBX3, HOXA6, DDIT3, CEBPG, MAX, ISL1, E2F4, LRRFIP1, TBPL2, FOXJ1, MED8, NDN, ZNF430, ZNF492, PER1, NKX2-2, ACTL6A, SPI1, PBX2, RFX5, SARNP, HSF5, NSD1, GATA5, DHX36, CALCOCO1, HIF3A, USP3, HOXA2, HNRNPC, SFPQ, HOXD3, BCL6, RFX3, SMARCA4, SREBF2, TFCP2, SMAD4, HNF4G, ZBTB6, ZNF750, HDAC2, PHOX2B, GZF1, TCF7L1, THAP1, LHX3, KDM6B, XBP1, HOXA5, BCL3, STAT5B, SUB1, ZNF746, NKX3-1, UBP1, HBP1, ELF1, SOX18, ZNF92, MXD1, SUZ12, ZNF502, JDP2, SMARCE1, NEUROD6, NKX1-2, TCFL5, RUVBL2, CREB3, NFATC1, HOXB5, H2AZ1, PBX3, HCFC1, FOSB, FOXA1, NKX3-2, MYT1, ZNF141, BATF, ZNF628, MYPOP, SPIC, ZNF114, ASCL2, EBF3, ZNF219, NFIB, BACH1, HOXB9, ATF7, MAZ, YBX1, HLTF, ZFHX4, CCAR1, KLF16, ZNF281, BHLHE40, MAFG, ZBTB11, NOTCH1, IRF9, RUNX1, SP3, NFATC3, REST, ZNF239, Z |
| RNA polymerase II core promoter sequence-specific DNA binding | molecular function | SOX3, STAT1, HSF1, HSF2, CDK9, TBPL2, RUVBL2, H2AZ1, GTF2B, REST, RELA, TAF1, GTF2A1, MACROH2A1, FOS, POU2F1, GBX2, H3-3A, POU2AF1 |
| RNA polymerase II CTD heptapeptide repeat phosphatase activity | molecular function | CTDSP2, CTDSPL2, SSU72, CTDSPL, CTDSP1, CTDP1 |
| RNA polymerase II distal enhancer sequence-specific DNA binding | molecular function | NR5A2, SOX10, NR5A1, NFE2L2, MBD2, MTA2, PROP1, ACTB |
| RNA polymerase II general transcription initiation factor activity | molecular function | GTF2H3, GTF2A2, TAF5, TAF12, CCNH, DR1, TAF9B, GTF2F1, GTF2B, TAF13, TAF7, TAF11, TAF3, SNAPC5, TAF6L, TAF5L, TAF1, GTF2A1, TAF2, TAF6, TAF4, GTF2F2, TAF10, GTF2H4, DRAP1, GTF2E2, GTF2E1, TAF9 |
| RNA polymerase II general transcription initiation factor binding | molecular function | DRAP1 |
| RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding | molecular function | HSF1, HSF2, NCOA2, ZNF350, ZC3H8, EMX2, VAX2, GSX1 |
| RNA polymerase II regulatory region sequence-specific DNA binding | molecular function | ATF3, NR1I2, SP1, HSF2, STAT4, PLAGL1, DMRT1, DMRT2, SOHLH1, ESX1, GATA4, MEF2A, ETV5, ZBTB5, GLI3, RBL1, RBL2, IKZF1, TFDP1, NR1D2, NFXL1, HOXD8, YBX3, MAX, PCGF3, ZNF700, AIRE, TBX10, ZIC2, PBX2, ESRRG, NHLH1, ZBTB4, RARB, ATF1, HOXD3, BCL6, NFX1, SMAD4, HNF4G, PCGF5, CREBRF, PHOX2B, LHX3, EOMES, ZNF14, XBP1, PURA, PPARD, BCOR, MACROH2A2, LYL1, RPS3, PRDM2, HES1, ZNF627, ASCL3, CREB3, NFATC1, EGR1, VEZF1, ASCL4, ASCL2, LMX1B, HOXB9, MXI1, TEF, ARID5B, HES6, BHLHE40, DUX1, CUX1, KLF3, RUNX1, SP3, DUX5, IER2, SCRT1, TFCP2L1, ZNF443, E2F3, GATA3, MSX1, RELA, MEF2C, TBR1, LIN54, JARID2, ARID3C, DEAF1, ATF4, RORA, HLF, ZNF791, NR2E3, ZNF205, NR2F6, NR4A2, LHX1, ASCL1, DBP, E2F2, STOX1, HES7, CGGBP1, CUX2, TFAP2A, NFKB2, SATB1, NHLH2, REL, KLF12, PBX1, EP300, ARID3B, NR1H4, TBX5, ARID3A, HOXC10, TWIST1, ZNF101, BCL6B, MLXIP, ZNF175, NCOR2, MACROH2A1, E2F6, NR2C1, FOSL2, ETV3, MEF2D, PKNOX2, FOXC2, TRPS1, JUNB, TFDP2, GBX1, ZNF57, DACH1, IRF2, ATF2, HOXD10, BHLHA15, MGA, RREB1, MNT, HEY2, LEF1, SALL2, TBX3, NCOR1, |
| RNA polymerase II repressing transcription factor binding | molecular function | SP1, MTA2, STAT3, SIN3A, TCF7L2, TCERG1, RBBP8, GTF2A2, MTA3, BBS2, MIER3, MIER1, BBS5, HDAC2, PPARD, DMAP1, MKKS, TTC8, MIER2, BBS4, MIXL1, GTF2A1, CHD4, RBPJ, GSC, DDRGK1, PPARA, BBS1 |
| RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity | molecular function | KLF4 |
| RNA polymerase II transcription coactivator activity | molecular function | MEF2A |
| RNA polymerase II transcription coactivator binding | molecular function | NFATC1, RELA |
| RNA polymerase II transcription corepressor activity | molecular function | SOX3, ELANE, SIN3A |
| RNA polymerase II transcription corepressor binding | molecular function | CNOT2 |
| RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding | molecular function | ESR1, ESR2 |
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | molecular function | NR5A2, ESR1, AR, VDR, AHR, NR5A1, ESR2, NR1I2, NR0B1, STAT3, NR2F2, PPARG, NR1H3, NR1D2, ESRRG, RARB, PPARD, NKX3-1, RORA, NR2E3, NR4A2, NR1H4, BRD8, NR1D1, SREBF1, RXRG, NR4A3, RARG, AHRR, NR4A1, PPARA, THRA, RORC, RARA, NR1H2 |
| RNA polymerase II transcription factor activity, sequence-specific DNA binding | molecular function | TP53, SOX9, SOX10, HIF1A, SRY, PEG3, STAT3, GATA4, MEF2A, FOXO1, FOXM1, ZNF174, ETV2, ZBTB5, SHOX, HOXA3, GLI3, SKIL, HOXD13, TCF7, IRX6, MLLT1, TFDP1, NR1D2, E2F5, ZMYM1, NFXL1, OLIG3, ZMYM2, FOXJ3, KLF4, HOXD8, YBX3, PAX7, HOXA6, DDIT3, CEBPG, MAX, ISL1, CREB5, KLF9, ELF2, E2F4, QRICH1, ZBED5, ZC3H8, FOXJ1, ZHX1, AIRE, TBX10, NKX2-2, ZIC2, SPI1, PBX2, RFX5, ESRRG, IRX1, NHLH1, HSF5, MIER3, MIER1, THAP6, GATA5, RCOR3, HIF3A, HOXA2, RARB, ATF1, HOXD3, RFX3, DR1, SREBF2, TFCP2, NFX1, SMAD4, HNF4G, CREBRF, BHLHE22, PHOX2B, NEUROG2, TCF7L1, THAP1, RERE, LHX3, EOMES, XBP1, HOXA5, STAT5B, PPARD, LCOR, NKX3-1, UBP1, FOXN3, HBP1, TSC22D2, LYL1, ELF1, SOX18, SP4, MXD1, PRDM2, ZMYM3, HES1, PCBP1, TSC22D1, ADNP2, JDP2, CSRNP3, ZNF414, NEUROD6, FEV, CSRNP2, ASCL3, NKX1-2, TCFL5, NCOA3, CREB3, NFATC1, HOXB5, EGR1, BMPR1A, PBX3, FOSB, FOXA1, NKX3-2, MYT1, BATF, ASCL4, MYPOP, SPIC, ASCL2, EBF3, VSX1, NFIB, BACH1, LMX1B, HOXB9, ATF7, MXI1, MAZ, YBX1, TEF, MIDEAS, TSHZ1, ZFHX4, OLIG1, NEUROG1, HES6, EBF4, KLF16, ADNP, VGLL3, |
| RNA polymerase II transcription factor binding | molecular function | TP53, AR, GSK3B, MTA2, CTNNB1, GATA4, MEF2A, HDAC4, ZFPM2, SPEN, KLF4, PIAS1, PRDM13, SPI1, SMAD4, RERE, LHX3, PIAS2, HES1, ZMIZ1, NFATC1, CREBBP, HIRA, FBP1, MAMSTR, ATF4, ELK1, MIXL1, EP300, ID4, WWP2, TBX3, HCLS1, GFI1B, DACT1, TBX20, PITX3, GSC, GBX2, TBX6, HDAC5, PIAS3, PIAS4, ZMIZ2, TEAD3, ZFPM1, ANKRD1, GATA1, PITX2 |
| RNA polymerase II-specific DNA-binding transcription factor binding | molecular function | PSMD10, ANKRD2, HES6, TAF1, MYOCD, SRF, ANKRD1, HSPB1 |
| RNA polymerase III core binding | molecular function | MAF1 |
| RNA polymerase III general transcription initiation factor activity | molecular function | SNAPC5 |
| RNA polymerase III transcription regulatory region sequence-specific DNA binding | molecular function | TBPL2, PRDX5 |
| RNA polymerase III type 1 promoter DNA binding | molecular function | MTOR |
| RNA polymerase III type 1 promoter sequence-specific DNA binding | molecular function | MAF1, RPTOR |
| RNA polymerase III type 2 promoter DNA binding | molecular function | MTOR |
| RNA polymerase III type 2 promoter sequence-specific DNA binding | molecular function | MAF1, RPTOR |
| RNA polymerase III type 3 promoter DNA binding | molecular function | MTOR |
| RNA polymerase III type 3 promoter sequence-specific DNA binding | molecular function | SNAPC3, BRF2, MAF1, RPTOR, BRF1 |
| RNA pyrophosphohydrolase activity | molecular function | DXO |
| RNA stem-loop binding | molecular function | FMR1, DDX3X, MYH10, ZC3H12A, EPRS1, RC3H2, RC3H1, LARP6, CPEB3, EIF4A3, METTL16 |
| RNA strand annealing activity | molecular function | FMR1, DDX3X, FXR1, EIF4B |
| RNA transmembrane transporter activity | molecular function | SIDT2, SIDT1 |
| RNA trimethylguanosine synthase activity | molecular function | TGS1 |
| RNA uridylyltransferase activity | molecular function | TUT1, TUT4, TUT7 |
| RNA-3'-phosphate cyclase activity | molecular function | RTCA |
| RNA-dependent ATPase activity | molecular function | DDX39B, DDX17, DDX11, IGHMBP2 |
| RNA-directed 5'-3' RNA polymerase activity | molecular function | TERT, POLR2A |
| RNA-directed DNA polymerase activity | molecular function | TERT |
| RNA-DNA hybrid ribonuclease activity | molecular function | APEX1, FEN1, RNASEH2B, EXO1, RNASEH2A, RNASEH1 |
| Roundabout binding | molecular function | LRTM1, SLIT1, TGFB1I1, LGR6, MYO9B, SLIT3, SLIT2, LRTM2 |
| rRNA (adenine) methyltransferase activity | molecular function | TRMT61B, BMT2 |
| rRNA (adenine-N6,N6-)-dimethyltransferase activity | molecular function | TFB2M, DIMT1, TFB1M, RRNAD1 |
| rRNA (adenine-N6-)-methyltransferase activity | molecular function | METTL5 |
| rRNA (cytosine-C5-)-methyltransferase activity | molecular function | NSUN5, NOP2 |
| rRNA (cytosine-N4-)-methyltransferase activity | molecular function | METTL15 |
| rRNA (guanine) methyltransferase activity | molecular function | BUD23, FTSJ3 |
| rRNA (guanosine-2'-O-)-methyltransferase activity | molecular function | MRM3 |
| rRNA (pseudouridine) methyltransferase activity | molecular function | EMG1 |
| rRNA (uridine-2'-O-)-methyltransferase activity | molecular function | FTSJ3 |
| rRNA binding | molecular function | RPL5, RPS4X, MRPL20, RPF1, IMP3, MRPL16, RPS18, RPL11, FASTKD5, PTCD3, MRPS17, SBDS, RPS9, RPL9, RPS5, ERAL1, TACO1, DDX21, MRPS7, FASTKD2, RPS4Y1, RPL8, RPF2, MRPL11, RNASEL, RCC1L, ERI1, RPL12, MRPS27, RPL37, EMG1, RPL23A, RPS11, NOL12, DIEXF, ANG, MTERF4, NGRN, CAVIN1, RPS4Y2, PPAN, MRPS6 |
| rRNA cytidine N-acetyltransferase activity | molecular function | NAT10 |
| rRNA methyltransferase activity | molecular function | TFB2M, DIMT1, FBL, TFB1M, RRNAD1, FTSJ3 |
| rRNA primary transcript binding | molecular function | CAVIN1 |
| RS domain binding | molecular function | SARNP, SRSF12, SON, LUC7L |
| ryanodine-sensitive calcium-release channel activity | molecular function | RYR1, RYR2, FKBP1B |
| S-(hydroxymethyl)glutathione dehydrogenase activity | molecular function | ADH4, ADH5 |
| S-acetyltransferase activity | molecular function | FASN |
| S-adenosyl-L-methionine binding | molecular function | CBS, GNMT, KMT5B, METTL5, PRMT8, TPMT, BMT2, SUV39H2, TSR3, PRMT1, KMT5C, PCIF1 |
| S-adenosyl-L-methionine transmembrane transporter activity | molecular function | SLC25A26 |
| S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity | molecular function | INMT |
| S-adenosylmethionine-dependent methyltransferase activity | molecular function | GAMT, PEMT, PRMT8, TPMT, MEPCE, LCMT1, ARMT1, CARNMT1, NOP2, PRMT7, N6AMT1 |
| S-adenosylmethionine-homocysteine S-methyltransferase activity | molecular function | MTR |
| S-formylglutathione hydrolase activity | molecular function | ESD |
| S-malonyltransferase activity | molecular function | MCAT, FASN |
| S-methyl-5-thioadenosine phosphorylase activity | molecular function | LACC1, MTAP |
| S-methyl-5-thioribose-1-phosphate isomerase activity | molecular function | MRI1 |
| S-methylmethionine-homocysteine S-methyltransferase activity | molecular function | BHMT2 |
| S-nitrosoglutathione binding | molecular function | GSTP1 |
| S100 protein binding | molecular function | EZR, ANXA2, S100A11, ATP2A2, IQGAP1, S100A6, ANXA11, AHNAK, CACYBP, S100B, KCNK3, FGF1, S100A1, AGER |
| saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity | molecular function | AASS |
| saccharopine dehydrogenase (NADP+, L-lysine-forming) activity | molecular function | AASS |
| SAM domain binding | molecular function | L3MBTL1, DGKH |
| Sar guanyl-nucleotide exchange factor activity | molecular function | PREB |
| sarcosine dehydrogenase activity | molecular function | SARDH |
| sarcosine oxidase activity | molecular function | PIPOX |
| satellite DNA binding | molecular function | MBD2, MLH3, MBD4, CENPB |
| scaffold protein binding | molecular function | NOS3, MAPK3, MDM2, CASP8, VIM, PARK7, SRC, GJA1, GRM3, BAIAP2, CIT, NLGN4X, MAP3K7, KCNH2, PHF6, BRAF, NCK2, PANX1, KIF1B, KRT18, UBTF, CAV2, TREM1, DSP, NLGN4Y, MAP2K2, YWHAE, CRIPT, CACNA1G, PDE4D, DLG4, TCOF1, GRM2, TREM2, IKBKB, P2RY1, MAP2K1, ITPR2, GRID2, CACNA1H, KRT8, DLL1, CRK, ADCY5, KRT15, AKAP5, DYNLL2, LRP4, SHANK1, SCN5A, CDC37 |
| scavenger receptor activity | molecular function | LGALS3BP, MEGF10, ACKR4, ENPP2, SCARB2, CXCL16, LOXL2, COLEC12, SCARB1, MARCO, DMBT1, ENPP1, ACKR3, SSC4D, TMPRSS2, PRSS12, TMPRSS15, STAB1, HHIPL1, TMPRSS3, VTN, LRP1, SCARF2, LOXL3, SCARA3, SCARA5, CD6, PRG4, SSC5D, CD163, TMPRSS4, SCARF1, TMPRSS13, CD5, TMPRSS5, CFI, STAB2, CD163L1, ACKR2, CD36, AGER |
| scavenger receptor binding | molecular function | FPR2 |
| secalciferol 1-monooxygenase activity | molecular function | CYP27B1 |
| second spliceosomal transesterification activity | molecular function | SLU7 |
| secondary active organic cation transmembrane transporter activity | molecular function | SLC22A4, SLC22A1 |
| secondary active sulfate transmembrane transporter activity | molecular function | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC13A1, SLC26A2, SLC26A11, SLC26A1, SLC26A10, SLC26A6 |
| secondary active transmembrane transporter activity | molecular function | SLC25A16 |
| secretin receptor activity | molecular function | SCTR |
| sedoheptulokinase activity | molecular function | SHPK |
| sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity | molecular function | TALDO1 |
| selenide, water dikinase activity | molecular function | SEPHS1, SEPHS2 |
| selenite:proton symporter activity | molecular function | SLC39A8 |
| selenium binding | molecular function | SELENOP, SELENOT, GPX3, DIO2, RPH3A, SELENBP1 |
| selenocysteine insertion sequence binding | molecular function | RPL30, SECISBP2L, SECISBP2, EIF4A3, EEFSEC |
| selenocysteine lyase activity | molecular function | SCLY |
| semaphorin receptor activity | molecular function | PLXNC1, NRP2, PLXNA1, PLXNA4, PLXNB3, NRP1, PLXNA3, PLXNB2, PLXNB1, PLXNA2, PLXND1 |
| semaphorin receptor binding | molecular function | SEMA7A, SEMA3A, SEMA3E, SEMA6D, SEMA3F, SEMA4C, SEMA3G, SEMA4G, SEMA4D, RIT2, SEMA6A, SEMA3B, SEMA3C, SEMA6C, SEMA6B, PLXNB1, SH3BP1, SEMA4B, SEMA5A |
| sepiapterin reductase activity | molecular function | SPR |
| sequence-specific DNA binding | molecular function | NR5A2, ESR1, TP53, PGR, AR, BCL2, VDR, RAG1, ATF3, WT1, SOX9, NR5A1, HIF1A, ESR2, NR1I2, SP1, HNF1B, NR0B1, HSF1, E2F1, HSF2, EZH2, NFE2L2, CTCFL, DMRT1, MTA2, NR3C1, STAT3, DMRT2, ESX1, PROP1, THRB, NR2F2, OTX1, PPARG, GATA4, SOX2, MEF2A, EMX1, FOXO1, HSFY1, CLOCK, USF1, ETV5, CREM, NR1H3, MAEL, RHOXF2, TP63, TCF7L2, FOXM1, ETV2, SHOX, HOXA3, GLI3, HOXD13, HDAC4, IRX6, HNRNPU, NR1D2, E2F5, Dmrtc2, ZNF440, ZNF669, OVOL2, BCL11A, FOXJ3, TRIM24, KLF4, HOXD8, PAX7, HOXA6, CEBPG, MAX, ISL1, ELF2, E2F4, SNAPC1, ZC3H8, FOXJ1, MTA3, ZNF768, NKX2-2, SPI1, PBX2, RFX5, ESRRG, IRX1, HSF5, ZNF620, GATAD1, GATA5, ZBTB4, CALCOCO1, CHCHD2, HOXA2, RARB, ATF1, HOXD3, BCL6, RFX3, TFCP2, SMAD4, HNRNPD, HNF4G, HDAC2, PHOX2B, GZF1, THAP1, SLTM, RERE, LHX3, KDM6B, EOMES, XBP1, HOXA5, PURA, PPARD, ZNF77, NKX3-1, UBP1, FOXN3, ELF1, SOX18, SP4, PRDM2, HES1, SUZ12, ZNF529, PHF6, CSRNP3, FEV, CSRNP2, NKX1-2, HOXB5, EGR1, ZNF10, RPA1, PBX3, FOSB, FOXA1, NKX3-2, BATF, SPIC, HNRNPAB, ASCL2, VSX1, PPARGC1A, LMX1B, HOXB9, TEF, ZNF177, CBFB, |
| sequence-specific double-stranded DNA binding | molecular function | HOXD13, HNRNPU, KDM5B, HNRNPD, HNRNPAB, NEUROG1, LMNB1, ETS1, HNRNPDL, ABL1, AHRR |
| sequence-specific mRNA binding | molecular function | FMR1, SRSF4, TYMS, ETF1, SSB, SRSF3, DHFR, SHFL, LARP6, RBM24, LIN28A |
| sequence-specific single stranded DNA binding | molecular function | PCBP1 |
| Ser-tRNA(Ala) hydrolase activity | molecular function | AARS1, AARSD1 |
| serine binding | molecular function | SHMT1, SHMT2, THNSL2, GRM7 |
| serine C-palmitoyltransferase activity | molecular function | SPTLC3, SPTLC1, SPTSSA, SPTLC2 |
| serine hydrolase activity | molecular function | CELA2A, AADAC |
| serine racemase activity | molecular function | SRR |
| serine transmembrane transporter activity | molecular function | SFXN1, SFXN3, SFXN2, SLC38A5 |
| serine-pyruvate transaminase activity | molecular function | AGXT |
| serine-tRNA ligase activity | molecular function | SARS2, SARS1 |
| serine-type carboxypeptidase activity | molecular function | CPN1, CPVL, PRCP, CTSA, CPD, SCPEP1 |
| serine-type endopeptidase activity | molecular function | F10, MMP2, MMP9, C3, KLK3, CTSD, LTF, ACR, HGF, MMP12, PLAU, PLAT, MMP7, ELANE, PARL, KLK9, CFD, PROC, TPSB2, TPSAB1, CLPP, CTSC, LONP2, RHBDL2, HTRA2, F7, GZMB, APEH, MBTPS1, RHBDF1, TPSG1, CELA3B, C1S, CTRL, TMPRSS11B, TMPRSS12, HPN, CELA2A, PRSS22, F12, CTSG, TMPRSS9, TMPRSS2, TMPRSS11D, KLK8, CFB, CELA3A, GZMH, MASP1, PRSS12, HGFAC, TPSD1, TMPRSS11E, PCSK2, PCSK6, HTRA4, TMPRSS15, PRSS54, PCSK4, PRSS58, PRSS23, KLK15, TPP1, RHBDL1, RHBDD1, PRSS21, KLK2, DPP4, PREPL, RHBDD2, MST1, PRSS3, TMPRSS3, TPP2, KLK13, GZMA, KLK10, HPR, HP, PLG, PCSK1, KLK5, C1R, KLK1, AZU1, PRSS57, PIK3IP1, PRSS50, PRSS27, MASP2, C2, FURIN, PRTN3, ADAM8, HTRA1, PRSS38, F2, CTSH, GZMM, PRSS36, TMPRSS6, PCSK9, TMPRSS4, KLK12, LONP1, PCSK7, PRSS53, MST1L, RHBDF2, KLK6, TMPRSS13, KLK11, ST14, PROZ, PREP, RHBDL3, HTRA3, HABP2, TMPRSS5, CFI, CTRB1, MMP8, C1RL, KLK4, KLK7 |
| serine-type endopeptidase inhibitor activity | molecular function | SERPINC1, ANOS1, SERPINE1, TFPI2, SERPINA1, APP, A2M, SERPINA5, EPPIN, SPINK1, SERPINA3, SLPI, WFDC9, SERPINB7, TFPI, WFDC10A, SPINK5, ITIH2, SERPINB6, WFDC8, PEBP1, SPINT2, SERPINB2, SERPINB9, COL7A1, WFDC13, WFDC1, SPINT1, APLP2, SERPINF2, SERPINB1, SERPINA7, SERPINA4, SPINK6, SERPINB3, SPINT3, SERPINB5, PI3, SPOCK1, WFIKKN2, SERPINI1, WFDC2, SERPINB8, ITIH6, CD109, WFIKKN1, HRG, SERPING1, SERPINA10, FURIN, COL6A3, SERPINF1, ITIH4, WFDC3, WFDC12, AMBP, ITIH5, SERPINA9, SERPINA12, A2ML1, AGT, COL28A1, WFDC5, HMSD, PAPLN, RECK, SERPINH1, ITIH3 |
| serine-type exopeptidase activity | molecular function | HPN, PREPL, PREP |
| serine-type peptidase activity | molecular function | F10, KLK3, LTF, ACR, DPP6, PLAU, PLAT, DPP8, ELANE, SEC11A, PARL, SEC11C, KLK9, CFD, PROC, TPSB2, TPSAB1, CLPP, LONP2, IMMP1L, RHBDL2, HTRA2, F7, GZMB, APEH, MBTPS1, TPSG1, CELA3B, C1S, CTRL, PRCP, TMPRSS11B, TMPRSS12, NAALAD2, HPN, CELA2A, PRSS22, F12, CTSG, TMPRSS9, TMPRSS2, TMPRSS11D, KLK8, CFB, CELA3A, GZMH, MASP1, PRSS12, HGFAC, TPSD1, TMPRSS11E, PCSK2, PCSK6, HTRA4, TMPRSS15, PCSK4, PRSS58, PRSS23, KLK15, TPP1, RHBDL1, RHBDD1, IMMP2L, PRSS21, KLK2, DPP4, PREPL, PRSS3, TMPRSS3, TPP2, NUP98, KLK13, GZMA, KLK10, PLG, PCSK1, KLK5, C1R, KLK1, PRSS57, PRSS27, MASP2, C2, FURIN, PRTN3, HTRA1, PRSS38, F2, GZMM, PRSS36, TMPRSS6, PCSK9, TMPRSS4, KLK12, LONP1, PCSK7, PRSS53, DPP9, KLK6, TMPRSS13, KLK11, ST14, PREP, RHBDL3, HTRA3, HABP2, TMPRSS5, CFI, CTRB1, RELN, C1RL, KLK4, RBP3, KLK7 |
| serotonin binding | molecular function | HTR3A, SLC6A4, HTR1E, HTR2C, HTR1B, HTR5A, HTR2B |
| serotonin-gated cation-selective channel activity | molecular function | HTR3B, HTR3A, HTR3E |
| serotonin:sodium symporter activity | molecular function | SLC6A4, SLC18A2 |
| serpin family protein binding | molecular function | CTSL |
| serum response element binding | molecular function | SRF |
| SET domain binding | molecular function | WIZ |
| SH2 domain binding | molecular function | SRC, JAK2, RACK1, NUP62, PTK2, DLC1, RUFY1, SYK, PTPN6, CCDC88A, LAT2, AFAP1L2, SYP, CTR9, IRS1, ARHGAP5, SQSTM1, SKAP1, SHCBP1, NLK, ABL1, PAG1, DAG1, LCK, CRK, SLAMF1, SH3PXD2B, SYNGR3, AFAP1, SH2B2, SIGLEC10, LAX1, SIT1 |
| SH3 domain binding | molecular function | CASP9, GPX1, KHDRBS1, CABYR, GJA1, SOS1, USP8, SIRPA, WIPF3, SYNJ1, PRRT2, LANCL1, ZNF106, SH3BGRL2, CIT, ERRFI1, VASP, TP53BP2, DPYSL3, CCDC6, DAB2IP, REPS1, WIPF1, RUFY1, PRKN, DENND1A, ABI2, PTTG2, SYNJ2, PTPN6, EPS15, BCAR1, NOXA1, AFAP1L2, CTTNBP2, SH2D2A, CYBA, ARHGAP17, DTX1, OSTF1, SHANK2, PTPN22, SH3BP2, RAPGEF1, ARHGAP27, MYPN, SKAP1, RUFY2, FUT8, PLSCR4, CD3E, RAD9A, ESPN, NCF1, LRP2, ARHGAP31, KHDRBS3, GRB2, ARHGAP1, ELMO2, EVL, WASF2, PLSCR1, SH3BP5, ABL1, CBL, ADAM9, GRIK5, DOCK3, ABI1, ARHGAP6, SH3BGRL, TOM1L1, LYN, DOCK1, ENAH, QKI, UVRAG, SOCS7, CD2AP, DNAJC6, HCLS1, ILK, ELMO3, MVB12A, PAK3, CBLB, EFS, WAS, CRK, PTPN12, ADAM19, AKAP5, DNM1, ENKUR, MAPK15, MICAL1, NCKIPSD, ITGB1BP2, CBLC, SH3BP1, SHANK1, HIP1R, CNTNAP1, AFAP1, SH3GL1, CRB3, ADAM12, FMN1, ELMO1, INPP5D, SH3KBP1, DRD4, DOCK4, ABI3, SGIP1 |
| SH3/SH2 adaptor activity | molecular function | SRC, KHDRBS1, PTPN11 |
| SHG alpha-glucan phosphorylase activity | molecular function | PYGL, PYGB, PYGM |
| short-chain carboxylesterase activity | molecular function | AADAC, ABHD2, ABHD1, NCEH1 |
| short-chain fatty acid transmembrane transporter activity | molecular function | SLC5A8, SLC22A9, CD36 |
| sialate O-acetylesterase activity | molecular function | SIAE |
| sialic acid binding | molecular function | SIGLEC8, SIGLEC11, SIGLEC6, ADIPOQ, SIGLEC7, SIGLEC12, SELP, ST8SIA2, ST8SIA4, SIGLECL1, FCN1, CD33, CD22, MAG, SIGLEC9, AGRN, ST8SIA3, SIGLEC10 |
| sialic acid transmembrane transporter activity | molecular function | SLC17A5 |
| sialic acid:proton symporter activity | molecular function | SLC17A5 |
| sialyltransferase activity | molecular function | ST6GALNAC6, ST6GAL1, ST6GALNAC4, ST8SIA2, ST8SIA4, ST6GAL2, ST6GALNAC2, ST8SIA1, ST3GAL4, ST6GALNAC5, ST6GALNAC1, ST3GAL6, ST8SIA5, ST3GAL1, ST3GAL2, ST6GALNAC3, ST8SIA3 |
| signal recognition particle binding | molecular function | SRP9, SRPRA, SRP72 |
| signal sequence binding | molecular function | AP2M1, AP2B1, SEC61A2, SEC61A1 |
| signal transducer activity | molecular function | EGFR, LHCGR, FSHR, FAS, GNAS, RXFP2, HMOX1, STAT1, GNAO1, EDNRA, GNRHR, CTNNB1, STAT3, GNAI1, FPR1, CHKA, PDCD1, GPRC6A, PROKR2, KISS1R, GJA1, F2R, TACR3, OXTR, CCR5, TAS2R38, OR2W3, PLCZ1, ECM1, MAS1, S100A9, FST, MALT1 |
| signal transducer activity, downstream of receptor | molecular function | RAF1, FLRT3 |
| signal transducer, downstream of receptor, with protein tyrosine kinase activity | molecular function | EGFR, ERBB2, KDR, INSR, KIT |
| signal transducer, downstream of receptor, with serine/threonine kinase activity | molecular function | AMHR2, BMPR2 |
| signaling adaptor activity | molecular function | SH2B3, NCK1, RACK1, DAB2IP, STAP1, MPP7, NCK2, AFAP1L2, SARM1, AXIN1, FCRL2, SLA2, EPS8, CDC42SE2, ZDHHC11, HOMER1, PAG1, STAP2, CRK, SH2B2, MAVS |
| signaling pattern recognition receptor activity | molecular function | TLR2, CLEC7A |
| signaling receptor activity | molecular function | PRNP, EIF2D, NR1D2, TRAM1, SELENOS, ANTXR1, MRC2, PAQR6, ATP6AP2, CSF2RB, SLC1A5, PAQR9, SEC63, TNFRSF11B, RARB, GRIN1, REG3A, NLGN4X, PAQR8, ADIPOR1, P2RY11, CSF3R, SEC62, DERL1, RTN4R, FZD4, LY75, ITGB5, PPARD, SLC20A1, CD93, OGFR, EPHB2, REG1B, TAS1R2, GP6, SLAMF8, THBD, BTLA, FKBP3, IL10RA, NLGN2, ROBO4, SIGLEC7, TNFRSF10B, NOTCH1, ANTXR2, TNFRSF17, ANXA2R, AMOT, SEMA4D, TNFRSF19, MRC1, CD86, TEK, REG3G, ADIPOR2, GABRA5, GUCY2F, TNFRSF9, TLR1, MMD, OGFRL1, TLR10, NRXN3, TNFRSF6B, ITGB6, CHRM3, CCR6, GUCY1B1, CUL5, LRRC19, TREM1, ANTXRL, CD48, GUCY1A1, PLA2R1, TREML4, NLGN4Y, LYVE1, NRP2, GRIA2, KIR2DL1, GRIN2C, NR1H4, PAQR3, PLXNA1, NR2C1, GRIK3, GRIK5, RNF139, RRBP1, NPC1, ITGB8, VAC14, GRIN2B, LILRA2, CD2, NR1D1, ITGAX, ITGB7, CXCR3, CD200R1, NOTCH4, P2RX7, CD244, TREM2, NOTCH3, ITGB2, P2RY1, LRP1, NECTIN1, GRIN3A, PAQR5, GRID2, LRRN2, CD4, RET, CD33, FPR2, TGFBR2, FOLR3, GUCY2D, KLRG1, TNFRSF13C, TNFRSF11A, TNFRSF10A, TSHR, MCC, APLNR, GRIA3, GRIK4, ACKR1, TREML2, PAQR4, SIGMAR1, XPR1, EDAR, TLR3, GFRA |
| signaling receptor complex adaptor activity | molecular function | SORBS1, SH2B3, NCK1, DLG5, DEDD2, NUP62, NCK2, CARD10, IRS1, SHANK2, GRIP1, CD3E, ROPN1B, CD3G, G3BP2, MMS19, LAT, RGS14, SHANK1, GRIP2, LRRK2, MAGI2 |
| single base insertion or deletion binding | molecular function | PMS2 |
| single guanine insertion binding | molecular function | MSH2, MSH6 |
| single thymine insertion binding | molecular function | MSH2, MSH6 |
| single-strand break-containing DNA binding | molecular function | APTX |
| single-strand selective uracil DNA N-glycosylase activity | molecular function | SMUG1 |
| single-stranded DNA 3'-5' exodeoxyribonuclease activity | molecular function | MEIOB, EXO5, ERI2, ISG20, EXD2, POLE |
| single-stranded DNA 5'-3' exodeoxyribonuclease activity | molecular function | EXO5, PLD4, EXO1, PLD3 |
| single-stranded DNA binding | molecular function | BRCA2, ERCC1, RAD23A, RAD23B, PARK7, MLH1, PMS2, MLH3, HSPD1, XPC, MSH2, MCM3, HNRNPU, DMC1, MEIOB, RBBP8, MCM8, SSBP1, HNRNPA1, RPA2, RBMS1, SWSAP1, HMCES, DHX36, POLR2G, NUP35, WBP11, SUB1, PURA, APTX, SSBP2, PCBP1, MCM9, ANXA1, RPA1, RNF138, YBX1, RTF1, SSBP3, REXO4, ERCC5, CDC45, TDP1, HMGB1, RAD52, HNRNPDL, LRPPRC, MCM5, TSN, FUBP1, NABP1, SAMHD1, TDP2, SHOC1, FUBP3, RPA3, FBH1, TSNAX, POLR3C, SMC4, PCBP2, ERCC4, RAD51B, RAD51D, BLM, POU4F1, MCM4, MCM7, PRIM1, HROB, STN1, MYEF2, MCM6, BIVM, SSBP4, RAD51AP1, NABP2, NME1, POLR2H, NEIL3, DDX11, HNRNPK, PURB, IMUP, TREX1, CRY2, LONP1, MCM10, IGHMBP2, MCM2, RAD18, SMC2, POLA1, MCMDC2 |
| single-stranded DNA endodeoxyribonuclease activity | molecular function | ERCC1, RBBP8, DCLRE1C, ENDOG, MRE11, RAD50, ERCC4, EXOG |
| single-stranded DNA exodeoxyribonuclease activity | molecular function | MGME1 |
| single-stranded DNA-dependent ATPase activity | molecular function | POLQ |
| single-stranded RNA binding | molecular function | PIWIL1, HNRNPF, SUPT4H1, HNRNPU, ZCCHC13, LACTB2, IFIH1, HNRNPA1, AGO4, A1CF, POLR2G, LSM14A, ANXA1, SNRPC, ENDOV, ZFR, ILF3, DHX58, AGO3, CBX8, CBX6, ZFR2, AGO2, RBM7, MSI1, DDX60, AGO1, TLR7, ADARB2, L1TD1, DDX11, CBX4, LONP1, DLX2 |
| single-stranded telomeric DNA binding | molecular function | HNRNPA2B1, RPA1, POT1, RAD50, STN1 |
| siRNA binding | molecular function | FMR1, MBD2, DICER1, FAM172A, TARBP2, MECP2, AGO2, TLR9, TLR7 |
| site-specific DNA-methyltransferase (adenine-specific) activity | molecular function | N6AMT1, METTL4 |
| site-specific endodeoxyribonuclease activity, specific for altered base | molecular function | APEX1 |
| SMAD binding | molecular function | CTNNB1, TGFBR3, MEF2A, SKIL, COL5A2, ACVR1B, PURA, ACVR1, ZMIZ1, COL3A1, BMPR1A, DAB2, STUB1, SKI, HMGA2, AXIN1, COL1A2, YY1, HIPK2, RNF111, IPO7, PML, TGFBR1, TOB1, SNW1, SMAD2, ZC3H3, USP15, RANBP3L, TGFBR2, TGFBRAP1, BMP2, SMURF2, ACVRL1, ZBTB7A, PURB, PRDM16, SMAD3, FOXH1, MAGI2 |
| small conductance calcium-activated potassium channel activity | molecular function | KCNN3, KCNN1, KCNN4, KCNN2 |
| small GTPase binding | molecular function | RAF1, IQGAP1, GDI2, ERRFI1, BRAF, PEX5, RCC2, PEX5L, RGL3, FGD6, FGD4, DENND10, RILP, FGD2, RILPL2, WAS, TSC2, RNF152, RILPL1, FGD5 |
| small molecule binding | molecular function | PAEP, PTGDS, SHMT1, OBP2A, LCN12, LCN9, OBP2B |
| small protein activating enzyme binding | molecular function | PARK7, UBA2, UBE2I, SAE1 |
| small ribosomal subunit rRNA binding | molecular function | RPS14, MRPS11, RPS13, MRPS18A, RPS3, MRPS18C, UTP23, MRPS6 |
| SMC family protein binding | molecular function | TENT4A |
| smoothened binding | molecular function | PTCH2, PTCH1, BBS1 |
| sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity | molecular function | GPAM, GPAT3 |
| sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity | molecular function | GPD2 |
| sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity | molecular function | GPD2 |
| SNAP receptor activity | molecular function | STX12, SEC22B, SNAP23, GOSR1, STX8, STX10, STX5, VTI1B, BNIP1, STX3, VAMP8, BET1L, STX18, VAMP1, SNAP29, STX17, STX7, STX1B, SNAP25, VAMP3, STX16, BET1, VAMP7, SNAP47, GOSR2, TSNARE1, VTI1A, STX4, STX11, YKT6 |
| SNARE binding | molecular function | STX12, SYT13, STX8, STX10, SNCA, NSF, SEC24C, STX5, ANKRD27, VTI1B, SNAPIN, STX3, TRIM9, CPLX1, NBAS, SYT1, PICALM, SYT5, SNAP91, STX17, STX7, STX1B, SYT12, SNAP25, EXOC3, VAMP3, STX16, VAMP7, GOSR2, SEC24D, VPS50, UVRAG, GABARAPL2, NAPA, TSNARE1, EXOC3L2, SYT17, VTI1A, STX4, SYT6, STX11, TNFAIP2, SYT9, CAPN10, SYT7, BAIAP3, SYT2, SYT3, SYT15, SYT10, LRRK2, CPLX2, EXOC3L1, CPLX3 |
| snoRNA binding | molecular function | IMP3, NUDT4, NOP58, NUDT5, NOP14, NOP10, DDX21, IMP4, SNU13, UTP6, NOP56, NUDT1, NUDT16, HEATR1, NUFIP1 |
| snRNA binding | molecular function | CDK9, HNRNPU, SNRNP70, NCBP2, SNRNP35, CCNT1, TOE1, GEMIN5, MEPCE, HEXIM2, RBM7, RBMXL3, HEXIM1 |
| snRNP binding | molecular function | SNRPB2, PRPF31 |
| sodium channel activity | molecular function | ASIC4, ASIC1, SCN11A, ASIC2, PKD2L1, SCN1B, SCNN1G, SCN2A, SCN1A, SCNN1A, SLC4A11, HCN2, KCNK1, HCN1, SCNN1D, SCN4A, SCN4B, HCN4, TRPM5, TRPM2, SCNN1B, SCN5A, ASIC3, NALCN, SCN10A, SCN2B, SCN3B, SCN8A |
| sodium channel inhibitor activity | molecular function | CAMK2D, NEDD4, SCN1B, COMMD1, NEDD4L, PCSK9, RSC1A1, SCN3B |
| sodium channel regulator activity | molecular function | FGF12, YWHAH, FXYD1, RANGRF, SGK2, CAV3, FXYD4, SCN1B, FXYD3, GPLD1, SCLT1, GPD1L, NEDD4L, SGK1, SGK3, TMPRSS3, PKP2, FXYD2, FXYD6, SNTA1, SCN4B, AGT, PTPN3, SCN2B, FXYD7, SCN3B |
| sodium ion binding | molecular function | PDXK, CAPN3, TDG, ATP1A2, ATP1B1, ATP1A1 |
| sodium ion transmembrane transporter activity | molecular function | ASIC4, SLC12A2, CNNM4, SLC23A1, SLC4A8, SLC12A3, SLC8A2 |
| sodium transmembrane transporter activity, phosphorylative mechanism | molecular function | ABCB11 |
| sodium-dependent L-ascorbate transmembrane transporter activity | molecular function | SLC23A1, SLC23A2 |
| sodium-dependent multivitamin transmembrane transporter activity | molecular function | SLC5A6 |
| sodium-dependent organic anion transmembrane transporter activity | molecular function | SLC10A6 |
| sodium-independent organic anion transmembrane transporter activity | molecular function | SLCO6A1, SLCO1B3, SLC22A9, SLCO5A1, SLC22A7, SLCO1A2, SLCO4C1, SLCO2B1, SLCO2A1, SLCO4A1, SLC22A11, SLCO1C1, SLCO3A1 |
| sodium:bicarbonate symporter activity | molecular function | SLC4A7, SLC4A4, SLC4A8, SLC4A10, SLC4A9 |
| sodium:chloride symporter activity | molecular function | SLC12A2, SLC12A3 |
| sodium:dicarboxylate symporter activity | molecular function | SLC13A3, SLC13A1, SLC13A5 |
| sodium:inorganic phosphate symporter activity | molecular function | SLC20A1, SLC20A2, SLC17A7 |
| sodium:iodide symporter activity | molecular function | SLC5A5 |
| sodium:phosphate symporter activity | molecular function | SLC17A3, SLC20A1, SLC17A1, SLC34A3, SLC20A2, SLC34A1, SLC17A2, SLC17A7 |
| sodium:potassium-exchanging ATPase activity | molecular function | ATP1A4, ATP1A3, ATP1A2, ATP1B1, FXYD2, ATP1A1, ATP1B2, ATP4A, ATP1B3, ATP4B |
| sodium:potassium:chloride symporter activity | molecular function | SLC12A2, SLC12A3 |
| sodium:proton antiporter activity | molecular function | SLC9C1, SLC9A2, SLC9A1, SLC9A7, SLC9A9, SLC9B2, SLC9C2, SLC9A6 |
| sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential | molecular function | SLC9A1 |
| sodium:sulfate symporter activity | molecular function | SLC13A1 |
| soluble NSF attachment protein activity | molecular function | NAPA, NAPB, NAPG |
| solute:proton antiporter activity | molecular function | SLC9C1, SLC9A2, SLC9A1, SLC9A7, TMCO3, SLC9A9, SLC9B2, CLCN3, SLC9C2, SLC9A6, CLCN4, CLCN5 |
| solute:proton symporter activity | molecular function | SLC33A1, MFSD3 |
| solute:sodium symporter activity | molecular function | SLC5A10 |
| somatostatin receptor activity | molecular function | SSTR4, SSTR3, SSTR5 |
| somatostatin receptor binding | molecular function | SHANK1 |
| sour taste receptor activity | molecular function | PKD2L1 |
| spectrin binding | molecular function | ANK1, KIF3A, USH1G, CAMSAP1, CAMSAP2, ANK3, GNB3, SPTBN5, DYNC1I1, GNB1, USH1C, SLC26A5, PTPRC, ANK2, GBP1, ADD3, ADD2, DCTN2, MYO10, PDE6G, ADD1, DMTN, MYO7A, SPTBN4, CAMSAP3, EPB41, EPB41L2 |
| spermidine binding | molecular function | SAT1, SATL1, SAT2 |
| spermidine synthase activity | molecular function | SRM |
| spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity | molecular function | PAOX |
| spermine synthase activity | molecular function | SMS |
| spermine:oxygen oxidoreductase (spermidine-forming) activity | molecular function | PAOX, SMOX |
| sphinganine kinase activity | molecular function | SPHK2 |
| sphinganine-1-phosphate aldolase activity | molecular function | PDXDC1 |
| sphingolipid activator protein activity | molecular function | GM2A |
| sphingolipid binding | molecular function | S1PR1, PHB2, TRAF2 |
| sphingolipid delta-4 desaturase activity | molecular function | DEGS2, DEGS1 |
| sphingolipid transporter activity | molecular function | SPNS2, MFSD2B |
| sphingomyelin phosphodiesterase activator activity | molecular function | NSMAF, STX4 |
| sphingomyelin phosphodiesterase activity | molecular function | SMPD1, SMPDL3A, SMPD3, SMPDL3B, SMPD2, SMPD4, ENPP7 |
| sphingomyelin phosphodiesterase D activity | molecular function | SMPD4 |
| sphingomyelin synthase activity | molecular function | SGMS2, SAMD8 |
| sphingosine hydroxylase activity | molecular function | DEGS2 |
| sphingosine N-acyltransferase activity | molecular function | TLCD3B, CERS5, CERS4, CERS1, CERS6, CERS3 |
| sphingosine-1-phosphate phosphatase activity | molecular function | PLPP2, PLPP1, SGPP2, PLPP3, SGPP1 |
| sphingosine-1-phosphate receptor activity | molecular function | SPHK2, S1PR1, S1PR2, S1PR5, S1PR3, S1PR4 |
| splicing factor binding | molecular function | SF3B1, SF3B4 |
| squalene monooxygenase activity | molecular function | SQLE |
| squalene synthase activity | molecular function | FDFT1 |
| starch binding | molecular function | GPCPD1, STBD1 |
| STAT family protein binding | molecular function | DTX3L, PTPN2, PTPRT, EP300, H2BC9, FAM220A |
| stearoyl-CoA 9-desaturase activity | molecular function | SCD, SCD5, FADS2 |
| stem cell factor receptor activity | molecular function | KIT |
| stem cell factor receptor binding | molecular function | KITLG, SH2B3, SPRED1 |
| steroid 11-beta-monooxygenase activity | molecular function | CYP11B1, CYP11B2 |
| steroid 17-alpha-monooxygenase activity | molecular function | CYP17A1 |
| steroid 21-monooxygenase activity | molecular function | CYP21A2 |
| steroid binding | molecular function | ESR1, SHBG, PGR, AR, ESR2, NR3C1, SULT1E1, IGF1, CYP21A2, PGRMC2, PAQR6, ESRRG, PAQR9, PAQR8, UGT1A8, PGRMC1, HSD11B1, ESRRA, PAQR5, HSD11B2, PDIA2, ESRRB, NR3C2, AKR1D1, PAQR7, GPER1 |
| steroid dehydrogenase activity | molecular function | AKR1C2, RDH14, HSD17B11, AKR1D1, AKR1C1, AKR1C4 |
| steroid delta-isomerase activity | molecular function | HSD3B1, HSD3B2, GSTA1, EBP |
| steroid hormone binding | molecular function | ESR2, NR3C1, SULT2B1, ATP1A3, ATP1A2, ATP1A1, GPER1 |
| steroid hormone receptor activity | molecular function | NR5A2, ESR1, PGR, VDR, NR5A1, ESR2, NR1I2, NR0B1, NR3C1, THRB, NR2F2, PPARG, NR1H3, NR1D2, PGRMC2, ESRRG, RARB, HNF4G, PAQR8, PPARD, ABHD2, RORA, NR2E3, NR2F6, NR4A2, NR1H4, NR2C1, ESRRA, NR1D1, HNF4A, NR2F1, RXRG, NR4A3, RARG, NR4A1, PPARA, THRA, RORC, ESRRB, NR3C2, PAQR7, RARA, NR2C2, NR1H2, GPER1 |
| steroid hormone receptor binding | molecular function | NR0B1 |
| steroid hydroxylase activity | molecular function | CYP1A1, CYP19A1, CYP2B6, CYP21A2, CYP11B2, CYP2J2, CYP2R1, CYP2A7, CYP2C8, CH25H, CYP2A6, CYP2C19, CYP3A5, CYP2C18, CYP2E1, CYP46A1, CYP2D6, CYP2S1, CYP2D7, CYP2W1, CYP2C9, CYP3A43 |
| steroid sulfotransferase activity | molecular function | SULT1E1, SULT1A1, SULT2A1, SULT2B1 |
| sterol 12-alpha-hydroxylase activity | molecular function | CYP8B1 |
| sterol 14-demethylase activity | molecular function | CYP51A1 |
| sterol 5-alpha reductase activity | molecular function | SRD5A2 |
| sterol binding | molecular function | SCP2, SCAP, OSBPL1A, OSBPL5, OSBPL11, OSBPL8, OSBPL2, OSBP2, OSBPL9, OSBPL6, OSBPL10, OSBPL7, OSBP, OSBPL3 |
| sterol delta7 reductase activity | molecular function | DHCR7 |
| sterol esterase activity | molecular function | CES4A, CES1, LIPA, NCEH1 |
| sterol O-acyltransferase activity | molecular function | SOAT1 |
| sterol response element binding | molecular function | NR1H3, SREBF1 |
| sterol transfer activity | molecular function | OSBP |
| sterol transporter activity | molecular function | ARV1, OSBPL1A, OSBPL5, OSBPL11, OSBPL8, OSBPL2, OSBP2, OSBPL9, OSBPL6, NPC1, OSBPL10, OSBPL7, OSBP, OSBPL3 |
| sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity | molecular function | NSDHL |
| steryl-beta-glucosidase activity | molecular function | GBA2 |
| steryl-sulfatase activity | molecular function | STS |
| store-operated calcium channel activity | molecular function | TRPC3, STIM2, TRPC7, TRPC1, TRPC5, TRPC4, ORAI2, ORAI3 |
| strictosidine synthase activity | molecular function | APMAP |
| structural constituent of bone | molecular function | BGLAP, MGP |
| structural constituent of cytoskeleton | molecular function | VIM, TUBB2B, ACTB, TUBB3, SYNM, TPM1, ANK1, TUBA4A, TUBA3C, TUBA8, ERBIN, TUBGCP4, DES, ACTR3, ARPC3, ANK3, ACTL7B, DMD, NEFH, PLEC, CCDC6, ARPC5, YEATS4, PLS1, KRT84, EPB41L3, EPB42, KRT6B, CTNNA2, SPTBN1, TUBB2A, BICD1, KRT6A, KRT20, CYLC2, TUBE1, TLN2, SPTBN2, TUBB, TUBA3D, DSP, TUBGCP3, ACTL7A, SORBS3, SORBS2, TUBB4B, ANK2, TUBG1, MSN, ADD3, KRT19, ADD2, CYLC1, ACTG1, EPB41L4B, PPL, ACTR2, TUBA1C, CD2AP, TUBB4A, SPTB, SPTAN1, TUBA3E, NEFM, ADD1, TUBB8, TUBB6, TUBAL3, KRT9, ARPC4, ARPC1B, ACTL6B, KRT15, TLN1, AGRN, KRT14, KRT2, TUBG2, GFAP, CROCC, SPTBN4, EPB41, BFSP2, INA, NEFL |
| structural constituent of egg coat | molecular function | POMZP3, ZP3 |
| structural constituent of epidermis | molecular function | KRT10, KRT84, SPRR1A, KRTAP5-8, FLG, PI3, KRT82, KRT2 |
| structural constituent of eye lens | molecular function | VIM, CRYBA4, CRYGA, CRYAB, CRYGS, CRYBA1, CRYGD, CRYGN, CRYBA2, CRYBB1, CRYAA2, CRYAA, LIM2, CRYBB2, BFSP2, CRYBG3 |
| structural constituent of muscle | molecular function | SYNM, TPM1, TCAP, MYOM2, MYL6, DMD, NEB, PLEC, NEXN, ANKRD2, CAPN3, MYH11, TPM4, MYBPC3, MYOM3, ACTN2, MYBPC2, TTN, SORBS2, NEBL, CSRP3, KRT19, MYBPC1, OBSCN, CSRP1, MYL5, ASPH, SMTN, MYL6B, MYL2, ACTN3, DAG1, PDLIM3, TPM2, JPH1, MYL3, MYH8, MYOM1, MYBPH |
| structural constituent of myelin sheath | molecular function | MALL, MARVELD1, MBP, MAL2, MAL, NCMAP, CMTM8, MOBP, PLLP |
| structural constituent of nuclear pore | molecular function | NUP93, NUP88, NUP85, NUP107, POM121, NUP35, NUP58, NPAP1, NUP205, NUP62, UPF3A, NUP155, NUP153, POM121L2, NUP133, UPF3B, NUP54, TPR, NUP98, NUTF2, NUP188, NUP214, NUP160 |
| structural constituent of postsynapse | molecular function | DNM3, ACTN1 |
| structural constituent of postsynaptic actin cytoskeleton | molecular function | ACTL8, ACTG1, ACTBL2, INA |
| structural constituent of postsynaptic density | molecular function | DLG1, DLG3, DLG2 |
| structural constituent of postsynaptic intermediate filament cytoskeleton | molecular function | NEFH, INA, NEFL |
| structural constituent of presynapse | molecular function | PPFIA2 |
| structural constituent of presynaptic active zone | molecular function | CTBP2, BSN, ERC2 |
| structural constituent of ribosome | molecular function | MRPS14, RPL4, RPL3, RPL5, RPS10, DAP3, RPS3A, RPL27, RPS7, RPS14, RPS4X, RPS6, RPL31, MRPS15, RPL24, RPL6, RPL10L, MRPL20, MRPL47, MRPL17, MRPL22, RSL24D1, RPLP0, MRPL3, RPL29, RPL15, RPS8, RPL7A, RPL32, RPS21, MRPS22, MRPS35, MRPS11, MRPS21, MRPS9, MRPL16, MRPS23, RPL7, RPL13, RPS18, RPS13, RPL11, RPL19, MRPL14, MRPL43, RPL39L, MRPL46, MRPS17, RPL35A, RPL21, RPS9, RPS20, RPL37A, RPS23, RPL41, MRPL49, RPS27L, SRBD1, MRPS30, MRPS18A, MRPL15, RPS2, RPL9, RPS19, RPS5, MRPL19, RPS25, RPL30, RPS27A, RPL38, MRPL51, MRPS24, MRPL35, MRPL27, RPS3, RPL13A, RPL35, RPL36AL, MRPS7, MRPS18C, RPLP1, RPS12, RPS27, RPL39, MRPL10, RPS4Y1, RPL8, MRPL37, MRPS33, MRPL11, RPL3L, MRPL33, MRPL23, MRPS12, RPL27A, MRPS25, RPL18A, NDUFA7, RPL12, RPL22, RPL28, RPL34, RPS16, RPS29, RPS15, RPL10A, MRPL54, MRPL57, MRPS16, RPL14, RPL37, RPS15A, RPS24, RPS28, MRPL21, MRPL55, MRPL41, RPL36, RPL10, MRPL34, RPL26L1, RPL22L1, MRPS31, RPLP2, RPS17, RPL23A, RPL18, MRPL52, UBA52, MRPL36, MRPS2, RPSA, RPL7L1, RPS11, MRPS34, RPL36A, RPL17, MRPL12, RP |
| structural constituent of synapse | molecular function | SPTBN2 |
| structural constituent of tooth enamel | molecular function | STATH, AMBN, TUFT1 |
| structural molecule activity | molecular function | BGLAP, KRT1, VIM, ODF2, NPHP1, CLDN11, KRT10, 39326, SYNM, NPHP4, ANK1, 38231, env, CLDN14, MATR3, CLDN6, CLDN2, ISCA2, KRT38, KRT75, ISCA1, EPB41L1, SEC31A, COPB2, COPB1, KRT24, CLDN9, CRYAB, CTNNA1, SEC13, CLDN15, PLEC, BVES, PANX3, KRT23, CLDN5, MPZ, EIF3A, MACF1, EPB41L3, COPE, ROCK2, DCTN3, MAP4, GNL1, SNTG2, FGG, CTNNA2, SPRR1A, SNTG1, PANX1, KRT18, LMNB1, KRT20, SPRR3, CLDN16, CLDN18, DST, SEH1L, KRTAP3-1, TLN2, FGB, FLG, KRT32, CLDN23, TUBB, DSP, PRPH, COL4A3, PGM5, LLGL1, KRT222, TUBGCP3, MAP2, PNN, COPG1, CLTA, ADD3, KRT19, ADD2, CYLC1, NUMA1, OLFM4, VCL, CLTCL1, CLDN17, EPPK1, CLTC, PPL, SPRR1B, COPA, KRT17, ASPH, TUBA1C, CLDN10, SNTB2, MPZL1, NEFM, LAMB1, HMGCL, EVPL, VPS25, CLTB, ADD1, SNTB1, SEPTIN5, COPG2, FGA, JUP, KRT85, LAMB3, LAMC3, CLDN1, CRYAA, KRT9, COL15A1, LAMA3, SEC31B, CLDN7, KRT15, SNTA1, CLDN4, KRT14, KRT13, JAG1, MAPK8IP2, TUBG2, EVPLL, TGM3, CROCC, PANX2, EPB41, CRYBB2, BFSP2, UPK1B, MAP1B, PSMD13, EPB41L2, CLDN8, SEPTIN7 |
| structural molecule activity conferring elasticity | molecular function | TTN, AHNAK |
| structure-specific DNA binding | molecular function | ERCC1 |
| substance K receptor activity | molecular function | TACR2 |
| substance K receptor binding | molecular function | TAC4 |
| substance P receptor binding | molecular function | TAC1, TAC4 |
| succinate dehydrogenase (ubiquinone) activity | molecular function | SDHB, SDHA |
| succinate dehydrogenase activity | molecular function | SDHA, SDHD, SDHC |
| succinate transmembrane transporter activity | molecular function | SLC13A3, SLC13A2, SLC13A1, SLC25A10, SLC13A5 |
| succinate-CoA ligase (ADP-forming) activity | molecular function | SUCLG1, SUCLA2, SUCLG2 |
| succinate-CoA ligase (GDP-forming) activity | molecular function | SUCLG1, SUCLG2 |
| succinate-hydroxymethylglutarate CoA-transferase activity | molecular function | SUGCT |
| succinate-semialdehyde dehydrogenase (NAD+) activity | molecular function | ALDH5A1 |
| succinate-semialdehyde dehydrogenase binding | molecular function | ABAT |
| succinate-semialdehyde dehydrogenase [NAD(P)+] activity | molecular function | ALDH5A1 |
| succinyl-CoA hydrolase activity | molecular function | ACOT4 |
| sucrose alpha-glucosidase activity | molecular function | SI |
| sucrose:proton symporter activity | molecular function | SLC45A2, SLC45A1, SLC45A4 |
| sugar transmembrane transporter activity | molecular function | SLC50A1 |
| sulfate adenylyltransferase (ATP) activity | molecular function | PAPSS2 |
| sulfate binding | molecular function | SMAD4, CD34, RCC1, SULT1A3 |
| sulfate transmembrane transporter activity | molecular function | SLC26A8, SLC26A4, SLC26A3, SLC26A9, SLC26A5, SLC26A7, SLC26A2, SLC25A10, SLC26A11, SLC26A1, SLC26A10, SLC26A6 |
| sulfatide binding | molecular function | PPT1, MANF, TPP1, CLN3, CLN6 |
| sulfide:quinone oxidoreductase activity | molecular function | SQOR |
| sulfinoalanine decarboxylase activity | molecular function | CSAD, GADL1 |
| sulfiredoxin activity | molecular function | SESN2, SRXN1 |
| sulfite oxidase activity | molecular function | SUOX |
| sulfonylurea receptor activity | molecular function | ABCC9, ABCC8 |
| sulfonylurea receptor binding | molecular function | HSP90AA1 |
| sulfotransferase activity | molecular function | SULT1E1, SULT1A1, SULT2A1, NDST4, TPST1, CHST12, GAL3ST3, SULT4A1, SULT2B1, HS3ST3A1, SULT1C2, DSEL, HS3ST2, CHST9, NDST1, CHST13, CHST6, HS6ST3, SULT1B1, NDST3, CHST4, SULT1C4, NDST2, HS3ST3B1, CHST10, SULT1A3, SULT1A4, HS3ST1, CHST14, SULT1A2, WSCD1, CHST5, GAL3ST2, CHST2, HS6ST1, HS2ST1, CHST3, CHST8, CHST11, HS3ST4, HS6ST2, GAL3ST4, HS3ST6, CHST7, UST |
| sulfur carrier activity | molecular function | URM1 |
| sulfur dioxygenase activity | molecular function | ETHE1 |
| sulfuric ester hydrolase activity | molecular function | ARSA, IDS, ARSH, SGSH, ARSB, ARSD, ARSK, GNS, GALNS, SULF1, ARSI, SULF2, ARSG, STS, ARSL |
| sulfurtransferase activity | molecular function | MOCS3, LIAS, TRMU, CTU2 |
| SUMO activating enzyme activity | molecular function | UBA2, SAE1 |
| SUMO binding | molecular function | SERBP1, TDG, UBA2, TOLLIP, USPL1, PML, USP25, HABP4, CBX4, HERC2 |
| SUMO conjugating enzyme activity | molecular function | UBE2I |
| SUMO ligase activity | molecular function | PIAS1, PIAS2, ZMIZ1, ZNF451, EGR2, KIAA1586, PIAS3, PIAS4, ZMIZ2 |
| SUMO polymer binding | molecular function | SIMC1, RNF111, CASP8AP2, SOBP |
| SUMO transferase activity | molecular function | MDM2, CDKN2A, HDAC4, PIAS1, NSMCE2, PIAS2, UBE2I, ZBED1, RANBP2, MUL1, PIAS3, PIAS4, CBX4, TOPORS |
| sumo-dependent protein binding | molecular function | PML |
| SUMO-specific endopeptidase activity | molecular function | SENP2, SENP6, SENP7 |
| SUMO-specific isopeptidase activity | molecular function | SENP2, USPL1, SENP1 |
| supercoiled DNA binding | molecular function | PSIP1, RPS3, HMGB1, ABL1 |
| superoxide dismutase activity | molecular function | SOD1, SOD2, NQO1, SOD3 |
| superoxide dismutase copper chaperone activity | molecular function | PARK7, ATP7A |
| superoxide-generating NADPH oxidase activator activity | molecular function | PDGFB, NOXO1, NOXA1, NCF1, NCF4, SH3PXD2B, SH3PXD2A, AGT |
| superoxide-generating NADPH oxidase activity | molecular function | NOX5, NOX1, CYBB, CYBA, NCF1, DUOX2, NCF4, DUOX1 |
| suramin binding | molecular function | RYR2 |
| symporter activity | molecular function | SLC22A18, SLC6A14, SLC13A3, SLC6A20, SLC16A7, SLC22A5, SLC6A8, SLC5A8, SLC28A2, SLC6A6, SLC28A1, SLC6A2, SLC12A2, SLC1A5, SLC36A4, SLC15A4, SLC17A3, SLC16A5, SLC24A5, SLC24A4, SLC20A1, SLC36A1, SLC25A18, SLC25A22, SLC4A7, SLC1A2, SLC15A2, MFSD4B, SLC38A1, SLC1A4, SLC13A2, SLC5A12, SLC17A5, SLC12A6, SLC4A4, SLC1A3, SLC17A1, SLC10A6, SLC6A15, SLC16A14, SLC38A2, SLC12A4, SLC6A11, SLC13A1, SLC6A16, SLC17A6, SLC38A4, SLC6A4, SLC25A3, MFSD2A, SLC1A6, SLC16A9, SLC10A3, SLC16A13, SLC4A11, SLC24A3, SLC23A1, SLC12A7, SLC16A8, SLC5A1, SLC6A12, SLC5A7, SLC22A4, SLC12A5, SLC5A6, SLC1A7, SLC5A2, SLC16A1, SLC34A3, SLC6A7, SLC16A6, SLC6A9, SLC20A2, MFSD12, SLC16A12, SLC6A5, MFSD2B, SLC6A19, SLC13A5, SLC6A18, SLC45A1, SLC12A3, SLC6A3, SLC34A1, SLC5A5, SLC38A3, SLC6A13, SLC23A2, SLC10A7, SLC28A3, SLC12A8, SLC17A2, SLC15A1, SLC4A10, SLC16A11, SLC17A7, SLC24A1, SLC10A2, SLC46A2, SLC6A17 |
| synaptic receptor adaptor activity | molecular function | HOMER2, SHANK2, SHANK1 |
| syndecan binding | molecular function | HPSE, PTN, GPNMB, SDCBP, TNC, CHRD, SEMA5A |
| syntaxin binding | molecular function | STXBP4, RAB11A, SEC22B, VPS52, VPS18, SNAP23, STX8, STX10, NSF, SCFD1, RAB4A, VAMP8, CPLX1, PTPN2, SYT1, VAMP1, STXBP5, SYT5, SNAP29, TXLNG, CACNA1A, STX7, SYT12, SNAP25, VAMP3, STX16, ABL1, VAMP7, SNAP47, TMED10, STXBP3, BLOC1S6, NAPA, TMED9, SYT6, SYT9, GOLGA2, SYT7, BAIAP3, STXBP2, SYT2, SYT3, DOC2B, SYT10, NAPB, STXBP5L, CPLX2, CPLX3, NAPG |
| syntaxin-1 binding | molecular function | PRRT2, SYPL1, NSF, CPLX1, SYT1, STXBP5, SNPH, SYP, SNAP25, VAMP3, UNC13C, SLC6A4, UNC13B, SYPL2, RNF40, STXBP3, DAPK1, UNC13A, STXBP2, LRRK2, CPLX2 |
| syntaxin-3 binding | molecular function | SYT1, STXBP2 |
| T cell receptor binding | molecular function | CD3E, CD3G, MR1, LCK, EPS8L1, DOCK2 |
| tachykinin receptor activity | molecular function | TACR3, TACR2 |
| talin binding | molecular function | CORO2B |
| TAP binding | molecular function | HLA-A |
| TAP complex binding | molecular function | TAPBP |
| TAP1 binding | molecular function | TAP1, TAP2, TAPBP, HLA-F |
| TAP2 binding | molecular function | TAP1, TAPBP, HLA-F |
| tapasin binding | molecular function | TAP2 |
| taste receptor activity | molecular function | TAS2R9, TAS1R2, TAS2R8, TAS2R1, TAS1R3, TAS1R1 |
| Tat protein binding | molecular function | ACTB, NPM1, SMARCA4, TRIM32, SMARCB1, GABARAPL1, MDFIC, DLL1, CTDP1 |
| tau protein binding | molecular function | APOE, FKBP4, GSK3B, DYRK1A, MARK3, PPP2CA, PPP2R2A, PIN1, MARK2, SNCA, ROCK2, LGMN, TAOK2, STUB1, PICALM, ROCK1, TTBK2, MAP2, EP300, TAOK1, AATF, SMAD2, S100B, PPP5C, HDAC6, CDK5, APBB1, BRSK1, MARK4, BIN1, MARK1, TTBK1 |
| tau-protein kinase activity | molecular function | GSK3B, BRSK2, DYRK1A, MARK3, MARK2, ROCK2, TAOK2, CSNK1D, ROCK1, TTBK2, PHKG2, TAOK1, SIK3, CDK5, PHKG1, BRSK1, MARK4, MARK1, TTBK1 |
| taurine binding | molecular function | GLRA1 |
| taurine transmembrane transporter activity | molecular function | SLC6A6 |
| taurine:sodium symporter activity | molecular function | SLC6A6 |
| TBP-class protein binding | molecular function | PSMC2, HNRNPF, GTF2A2, TAF12, DR1, PSMC5, RUVBL2, GTF2B, TAF13, TAF11, TAF1B, TAF1, GTF2A1, CAND1, RUVBL1, PSMC1, DRAP1, HHEX, CAND2, BRF1, THRA, YEATS2, ESR1 |
| telethonin binding | molecular function | TTN, CSRP3, KCNE1, MYOZ1, MYOZ2 |
| telomerase activity | molecular function | TERT, TEP1, DKC1, PTGES3 |
| telomerase inhibitor activity | molecular function | POT1, ERCC4, MCRS1, PINX1 |
| telomerase RNA binding | molecular function | TERT, TEP1, HNRNPU, DKC1, DHX36, PARN, HNRNPC, DCP2, NOP10, NHP2, WRAP53, SNRPB, SMG7, SMG6, XRN1, TENT4B, NAF1, SMG5, PINX1, GAR1 |
| telomerase RNA reverse transcriptase activity | molecular function | TERT |
| telomeric D-loop binding | molecular function | POT1, BLM, RECQL4 |
| telomeric DNA binding | molecular function | TERT, UPF2, TERF2IP, XRCC5, HNRNPD, UPF3A, POT1, UPF1, TINF2, XRCC6, SMG7, SMG6, SMG1, ACD, TP53BP1, HMBOX1, STN1, NCL, SMG5 |
| telomeric repeat-containing RNA binding | molecular function | HNRNPA1 |
| temperature-gated cation channel activity | molecular function | KCNK4, TRPA1 |
| temperature-gated ion channel activity | molecular function | TRPV1 |
| testosterone 17-beta-dehydrogenase (NADP+) activity | molecular function | HSD17B3, AKR1C3, HSD17B14 |
| testosterone 6-beta-hydroxylase activity | molecular function | CYP3A5, CYP3A43 |
| testosterone dehydrogenase (NAD+) activity | molecular function | HSD17B1, HSD17B3, HSD17B2, AKR1C3, DHRS9, HSD17B8, HSD17B6 |
| testosterone dehydrogenase [NAD(P)] activity | molecular function | HSD17B10 |
| tetracycline transmembrane transporter activity | molecular function | MFSD10 |
| tetrahydrobiopterin binding | molecular function | NOS3, NOS2, TH |
| tetrahydrofolyl-poly(glutamate) polymer binding | molecular function | FOLH1 |
| tetrahydrofolylpolyglutamate synthase activity | molecular function | FPGS |
| TFIIB-class transcription factor binding | molecular function | TCF4, ESR1 |
| TFIID-class transcription factor binding | molecular function | ERCC1, NOP58, RUVBL2, EDF1, FBL, RUVBL1, ZNHIT6, ERCC4, TP53 |
| TFIIF-class transcription factor complex binding | molecular function | GTF2F1, CTDP1 |
| TFIIH-class transcription factor complex binding | molecular function | HNRNPU, TAF7 |
| TFIIIC-class transcription factor binding | molecular function | MTOR, BDP1, RPTOR |
| thiamin-triphosphatase activity | molecular function | THTPA |
| thiamine binding | molecular function | TPK1 |
| thiamine diphosphokinase activity | molecular function | TPK1 |
| thiamine phosphate phosphatase activity | molecular function | ACPP |
| thiamine pyrophosphate binding | molecular function | TKTL1, HACL1, OGDH, TKTL2, ILVBL, TKT, OGDHL, DHTKD1 |
| thiamine pyrophosphate transmembrane transporter activity | molecular function | SLC44A4, SLC25A19 |
| thiamine transmembrane transporter activity | molecular function | SLC22A2, SLC19A3, SLC19A2, SLC22A1, SLC25A19 |
| thienylcyclohexylpiperidine binding | molecular function | CEP104 |
| thiocyanate peroxidase activity | molecular function | LPO |
| thioesterase binding | molecular function | CDC42, TRAF3, ADRA2A, RAC1, TRAF6, TRAF4, ARF6, TRAF5, TRAF1, TRAF2 |
| thioether S-methyltransferase activity | molecular function | INMT |
| thiol oxidase activity | molecular function | QSOX1, QSOX2, GFER, TMX3 |
| thiol-dependent ubiquitin-specific protease activity | molecular function | USP9Y, USP1, USP8, USP38, COPS5, USP47, USP13, EIF3F, USP14, ZC3H12A, USP16, USP3, PSMD14, MINDY1, MINDY3, USP32, STAMBPL1, USP28, USP29, USP30, USP51, USP37, PAN2, OTUD7A, UFD1, USP22, USP31, OTULIN, ATXN3, USP33, TANK, USP2, USP45, OTUB2, USP44, USP27X, CYLD, USP12, MYSM1, MINDY2, USP36, YOD1, USP7, USP48, USP25, USP4, USP34, USP9X, ZRANB1, USP15, USP11, USP49, OTUD5, STAMBP, JOSD2, USP10, OTUD6A, UCHL5, OTUD4, OTUD7B, USP20, USP35, USP21, USP6, BAP1, USP18, JOSD1, OTUD3, OTUD1, USP40, UCHL1, USP5 |
| thiol-dependent ubiquitinyl hydrolase activity | molecular function | USP9Y, USP1, USP26, USP8, USP38, USP47, USP13, EIF3F, USP14, MINDY4, USP16, USP3, PSMD14, MINDY1, MINDY3, USP32, USP28, DESI2, USP29, USP30, USP51, USP37, OTUD7A, USP22, USP31, OTULIN, USP53, ATXN3, USP33, ZUP1, USP2, USP45, OTUB2, USP44, USP27X, CYLD, USP12, MYSM1, MINDY2, USP36, USP39, YOD1, USP7, USP48, ALG13, USP25, USP4, USP34, USP9X, ZRANB1, USP15, USP11, USP49, OTUD5, JOSD2, USP10, OTUD6A, UCHL5, OTUD4, OTUD7B, USP20, USP35, USP21, USP6, USP43, BAP1, USP54, USP18, JOSD1, OTUD3, OTUD1, USP40, UCHL1, USP5 |
| thiolester hydrolase activity | molecular function | UFSP2, PPT1, BAAT, ACOT7, ACOT2, ACOT11, ACOT4 |
| thiopurine S-methyltransferase activity | molecular function | TPMT |
| thioredoxin peroxidase activity | molecular function | PRDX4, PRDX2, PRDX1, PRDX3, PRDX5 |
| thioredoxin-disulfide reductase activity | molecular function | TXNDC2, TXNRD1, SELENOT, NXN, TXNRD2 |
| thiosulfate sulfurtransferase activity | molecular function | MOCS3, TST, MPST |
| thiosulfate transmembrane transporter activity | molecular function | SLC25A10 |
| thiosulfate-thiol sulfurtransferase activity | molecular function | TSTD1 |
| threonine racemase activity | molecular function | SRR |
| threonine-tRNA ligase activity | molecular function | TARS1, TARS2, TARS3 |
| threonine-type endopeptidase activity | molecular function | PSMA3, PSMB1, PSMB5, PSMA8, PSMA7, PSMA1, PSMA2, PSMA5, PSMB2, PSMB7, PSMB6, PSMB4, PSMB8, PSMA6, PSMB9, PSMA4, PSMB3, PRSS50, TASP1, PSMB10 |
| thrombin-activated receptor activity | molecular function | F2R, F2RL3, F2RL2, GP1BA |
| thrombopoietin receptor activity | molecular function | MPL |
| thrombospondin receptor activity | molecular function | CD47, SDC4, F2, CD36 |
| thromboxane A2 receptor activity | molecular function | TBXA2R |
| thromboxane A2 receptor binding | molecular function | RPGRIP1L |
| thromboxane receptor activity | molecular function | TBXA2R |
| thromboxane-A synthase activity | molecular function | TBXAS1, CYP2S1 |
| thymidine kinase activity | molecular function | TK2, TK1 |
| thymidine phosphorylase activity | molecular function | TYMP |
| thymidylate kinase activity | molecular function | DTYMK |
| thymidylate synthase activity | molecular function | TYMS |
| thymine binding | molecular function | DPYS |
| thyroid hormone binding | molecular function | THRB, PKM, ALDH1A3, CTSH, THRA |
| thyroid hormone receptor activity | molecular function | THRB |
| thyroid hormone receptor binding | molecular function | NCOA2, FUS, MED4, TRIP12, HMGN3, NSD1, NCOA6, ZNHIT3, TACC1, NCOA3, GTF2B, TAF7, OASL, PRMT2, TAF11, MED13, GAS2L1, GTF2H1, MED30, NCOR1, MED16, MED12, ARID5A, THRAP3, MED24, TRIP6 |
| thyroid hormone receptor coactivator activity | molecular function | NCOA2, ACTN2, MED16 |
| thyroid hormone transmembrane transporter activity | molecular function | SLC16A10, SLCO4A1, SLCO1C1 |
| thyroid-stimulating hormone receptor activity | molecular function | PAX8, TSHR |
| thyrotropin-releasing hormone activity | molecular function | TRH |
| thyrotropin-releasing hormone receptor binding | molecular function | PSMC5, GPHA2 |
| thyroxine 5'-deiodinase activity | molecular function | DIO2, DIO3 |
| thyroxine 5-deiodinase activity | molecular function | DIO2, DIO3 |
| TIR domain binding | molecular function | MYD88 |
| titin binding | molecular function | CAMK2D, TCAP, ANKRD2, CAPN3, MYBPC3, ACTN2, CALM1, CALM2, CALM3, MYBPC1, OBSCN, ANKRD23, ANKRD1 |
| titin Z domain binding | molecular function | TCAP, ACTN2 |
| tocotrienol omega-hydroxylase activity | molecular function | CYP4F2 |
| Toll-like receptor 2 binding | molecular function | TIRAP, TLR1, TLR6 |
| Toll-like receptor 4 binding | molecular function | S100A9, LY96, DAB2IP, TIRAP, S100A8 |
| Toll-like receptor binding | molecular function | TLR2, MYD88, SYK, TOLLIP, UNC93B1, CD36 |
| TORC2 complex binding | molecular function | PINK1, RPL23A |
| toxic substance binding | molecular function | ALB, EPHX2, ASS1, CYP4B1, CHRNA7, A4GALT, DSG1, AZU1 |
| toxin transmembrane transporter activity | molecular function | SLC22A2, SLC17A3, ABCG1, SLC7A8, LRP6, LRP5, SLC22A1, SLC22A3 |
| TPR domain binding | molecular function | HSP90AA1, TRAK2, RAB8B, STUB1, TRAK1, SRP72, PDE2A |
| trace-amine receptor activity | molecular function | TAAR6, GPR21, TAAR5 |
| TRAIL binding | molecular function | TNFRSF10C, TNFRSF10D, TNFRSF10B, TNFRSF10A |
| trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity | molecular function | AKR1C3, AKR1C2, AKR1C1, DHDH |
| trans-2-enoyl-CoA reductase (NADPH) activity | molecular function | DECR2, PECR |
| trans-L-3-hydroxyproline dehydratase activity | molecular function | L3HYPDH |
| trans-octaprenyltranstransferase activity | molecular function | PDSS2, PDSS1 |
| transaminase activity | molecular function | PSAT1, GFPT1, GOT1L1, BCAT1, GPT, GOT1, GPT2, OAT, PHYKPL, ABAT, AGXT, AMT, KYAT1, TAT, AADAT, BCAT2, GOT2 |
| transcription coactivator activity | molecular function | BRCA1, NRIP1, SOX10, NR5A1, ESR2, NR1I2, HSF2, BRDT, CTNNB1, PARK7, RB1, NCOA2, MAK, APEX1, GATA4, TAF7L, NR1H3, TADA1, GTF2A1L, TBPL1, TCERG1, MED7, TADA3, FUS, UBE3A, NACA, RNF20, SETD3, ZFPM2, COPS5, MED4, TRIM24, NPM1, DDIT3, SMARCA2, GTF2A2, ISL1, DYRK1A, TAF5, TAF12, SRCAP, MTA3, ENY2, NKX2-2, ACTL6A, NCOA4, BICRAL, CARM1, NSD3, CALCOCO1, HIF3A, USP16, HCFC2, PSIP1, BCL10, SMARCA4, NPAT, NCOA6, UTF1, ASXL1, RERE, RNF14, DYRK1B, MAGED1, AIP, BCL9, SUB1, PPARD, TDRD3, ARL2BP, SUPT3H, SP4, JMY, SMARCE1, ZMIZ1, NCOA3, PHF2, PRPF6, HCFC1, ARID1B, CREBBP, PPARGC1A, PDLIM1, NUPR1, CBFB, ARID5B, SS18, SMARCD3, CCAR1, SOX12, EDF1, CTBP2, WNT3A, MED21, TAF7, MRTFA, CITED1, USP22, KMT2D, GATA3, PRMT2, ID3, TRIM32, LPIN1, TAF11, WWC1, PER2, TGFB1I1, MED14, MED6, DTX1, MED12L, CITED4, MED13, SUPT7L, HMGB1, PRRX1, SMARCB1, FHL5, SMARCC2, MYCBP, MED23, TAF6L, SOX11, BIRC2, SRA1, MRTFB, TAF5L, UBE2L3, EP300, GPS2, TRIP11, KMT2C, KAT5, HTATIP2, HIPK2, SIX3, NCOA1, MYSM1, RUVBL1, PSMD9, MED26, ABL1, SERTAD2, TRIP4, NFKBI |
| transcription coactivator binding | molecular function | ESR1, TERT, CDK9, FOXO1, SMAD4, PPARD, RORA, MED25, TEAD2, SIX1, VGLL4, RPL23, ZBTB17, FOXC1, NR4A3, TFAM, PPARA, RORC, SMAD3 |
| transcription cofactor activity | molecular function | NRIP1, MUC1, NRG1, TCERG1, MED7, FUS, EWSR1, DDX1, MED4, LPXN, PIAS1, MED8, BCLAF1, PIR, NSD1, TFB2M, CALCOCO1, PXN, BTG1, DR1, NPAT, AIP, PIAS2, SUPT3H, ZMIZ1, RYBP, SUPT20H, CREBBP, PPARGC1A, CBFB, TRIP13, HES6, SAP30L, MED21, TDG, TAF13, MAMSTR, MED10, GATA3, YY1AP1, TGFB1I1, MED14, MED6, NAB1, MED12L, MED13, FHL2, FHL5, MED31, SAP30, GON4L, MED13L, TAF15, EP300, BTAF1, MED26, TFDP2, MED30, CNOT2, TP53BP1, LDB1, TRERF1, MED12, MED15, MEIS2, MSX2, NFE2L1, PTPN14, THRAP3, LDB2, DRAP1, NAB2, PPRC1, PHF12, MED18, PPARGC1B, KAT2B, PRDM16, MED9, PIAS3, SND1, PIAS4, RALY, MED24, MED22, ZMIZ2, TCERG1L, POU2AF1, MED19, BCLAF3 |
| transcription cofactor binding | molecular function | NFE2L2, KLF4, BAIAP2, UBE2I, LMO2, CHD6, MAFK, FOXO3 |
| transcription corepressor activity | molecular function | ATF3, NRIP1, NR0B1, DNMT3B, ENO1, C1QBP, THRB, NR2F2, APEX1, SIN3A, TCERG1, RBFOX2, SKIL, HDAC4, HNRNPU, OLIG3, ZFPM2, SPEN, RBBP8, KDM5B, EID1, PIAS1, TLE1, CIR1, PAWR, TSG101, MTA3, ZHX1, ZNF136, MIER3, MIER1, NSD1, TRIB3, PFDN5, RCOR3, HIF3A, SIAH2, SMARCA4, DR1, NPAT, TAF9B, RERE, SIN3B, BCOR, RIOX2, IRF2BPL, SAP18, MXD1, JAZF1, DMAP1, HDAC9, RUVBL2, RUNX1T1, RYBP, CREBBP, NFIB, MXI1, HIRA, WNT4, CCAR1, AJUBA, LMCD1, ZNF281, BHLHE40, CCND1, CTBP2, PARP14, SCAI, CBFA2T3, SKI, COPS2, MLIP, MIER2, HDGF, EID2B, SFMBT1, HSBP1, LHX1, FHL2, PBXIP1, SAP30, GON4L, N4BP2L2, RLIM, KLF12, URI1, MECP2, TLE4, GPS2, HIPK2, ZNF451, BASP1, C1D, ATF7IP, SUFU, NCOR2, TDP2, ZMYND11, HDAC7, RCOR1, WTIP, PEX14, TOB1, CTBP1, SNW1, IRF2BP2, CREG1, DNAJB1, YAP1, CDYL2, MNT, CITED2, HDAC3, TBL1X, NCOR1, POU4F1, MAP3K10, TLE2, MXD4, RCOR2, SIRT6, E2F7, SIRT7, E2F8, CBFA2T2, SRSF2, POU4F2, ERF, ARID5A, KCTD1, AEBP1, CDX2, LIMD1, CASP8AP2, ZMYND8, TLE5, SF1, ZNF366, WWTR1, NAB2, PHF12, HR, NFIL3, MYBBP1A, NOC2L, PIAS4, SMYD1, KCNIP3, |
| transcription corepressor binding | molecular function | PER3, PER1, PER2, RORA, HDGF, SIX3, FAM89B, NR1D1, PHF12, ZBTB7A, NEK6, CDC5L |
| transcription elongation regulator activity | molecular function | TCERG1 |
| transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | ATF3, SP1, CLOCK |
| transcription factor activity, RNA polymerase II core promoter sequence-specific | molecular function | STAT1 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | molecular function | NR5A2, SOX9, SOX10, NR5A1, HIF1A, HNF1B, SRY, MEF2A, USF1 |
| transcription factor activity, RNA polymerase II transcription factor binding | molecular function | HIF1A, GATA4 |
| transcription factor activity, RNA polymerase II transcription factor recruiting | molecular function | LIF |
| transcription factor activity, sequence-specific DNA binding | molecular function | NR5A2, ESR1, TP53, PGR, AR, VDR, ATF3, WT1, AHR, SOX9, SOX10, NR5A1, HIF1A, ESR2, NR1I2, SP1, HNF1A, HNF1B, SOX3, STAT1, HSF1, E2F1, HSF2, SRY, STAT4, NFE2L2, PEG3, ARNT2, DMRT1, MTA2, NR3C1, ENO1, CTNNB1, STAT3, DMRT2, ZFP37, KAT7, RB1, SOHLH1, THRB, NR2F2, OTX1, PPARG, GATA4, SOX2, MEF2A, FOXO1, HSFY1, CLOCK, USF1, SOX5, ETV5, CREM, NR1H3, TAF4B, SIN3A, TSC22D3, NPAS2, TP63, TCF7L2, MYC, MYCN, FOXM1, ZNF174, ETV2, ZNF646, HOXA3, ZRANB2, GLI3, HOXD13, TCF7, IKZF1, TFDP1, NR1D2, E2F5, NFXL1, Dmrtc2, ZNF440, ZFP62, ZNF669, ZNF350, BCL11A, FOXJ3, KLF4, HOXD8, PAX7, HOXA6, DDIT3, CEBPG, MAX, CREB5, KLF9, ELF2, E2F4, PCGF3, TBPL2, ZC3H8, FOXJ1, ZNF768, ZHX1, TBX10, NKX2-2, ZIC2, SPI1, PBX2, RFX5, ESRRG, ZNF33A, ZSCAN26, HSF5, ZNF620, ZNF444, ZNF786, ZNF521, ZSCAN31, GATA5, ZSCAN16, ZBTB4, RCOR3, CNOT8, HIF3A, HOXA2, RARB, ATF1, HOXD3, BCL6, RFX3, SREBF2, TFCP2, NFX1, SMAD4, HNF4G, ZNF770, ZNF600, PCGF5, GPBP1, CREBRF, BLZF1, TCF7L1, EOMES, XBP1, HOXA5, BCL3, STAT5B, PURA, PPARD, ZNF77, ZNF746, NKX3-1, UBP1, FOXN3 |
| transcription factor activity, transcription factor binding | molecular function | HIF1A, MTA2, FOXO1, TP63 |
| transcription factor binding | molecular function | ESR1, TP53, AR, BCL2, AHR, SOX10, HIF1A, SP1, MAPK1, GSK3B, NR0B1, E2F1, SRY, CDKN2A, PARP1, CTNNB1, STAT3, CSNK2B, PARK7, RB1, C1QBP, NCOA2, PPARG, GATA4, CDK9, SUMO1, FOXO1, TAF7L, SIN3A, TCF7L2, NBN, MYC, RBFOX2, RBL1, HNRNPF, HDAC4, PER3, TFDP1, NR1D2, E2F5, ZFPM2, NIF3L1, DDX3X, KLF4, PIAS1, NPM1, DDIT3, GTF2A2, CEBPG, TLE1, KEAP1, E2F4, TAF12, TBPL2, STK36, DRG1, PER1, NKX2-2, SPI1, PBX2, HDAC11, RNF19A, RCOR3, HCFC2, CHCHD2, BCL10, RARB, PIK3R1, SMARCA4, TFCP2, STK4, ENPP2, HNRNPD, HDAC2, TAF9B, AIP, CCNT1, PIAS2, BCL3, GTF2F1, PURA, PPARD, BCOR, TRIM11, NKX3-1, HMGB3, PSMD10, RPS3, PSMC5, HES1, ASCL3, HDAC9, NFATC1, CD34, PBX3, HCFC1, FOSB, FOXA1, GTF2B, ASCL4, CREBBP, ASCL2, PPARGC1A, ATF7, MIDEAS, SMARCD3, CXXC5, HES6, CCND1, RUNX1, NFATC3, REST, TDG, TAF7, PELP1, APBB2, HDAC8, UBA2, E2F3, UBXN7, GATA3, YWHAZ, UBE2I, ID3, RELA, MEF2C, PPID, NFIA, TAF11, SIRT2, JARID2, TRIB1, PER2, MED6, ATF4, GPX3, RORA, CENPF, HMGA2, PDX1, SLC26A5, NFATC2, NAB1, TXLNG, HMGB1, ETS1, NFKBIA, ASCL1, FHL2, E2F2, HES7, |
| transcription regulatory region DNA binding | molecular function | NR5A2, TNF, TP53, AR, ATF3, WT1, AHR, BRCA1, SOX9, SOX10, SP1, HNF1A, HNF1B, E2F1, NFE2L2, CTCFL, MTA2, CTNNB1, STAT3, PPARG, GATA4, SOX2, CDK9, TAF7L, HNRNPL, ETV5, NR1H3, TP63, TCF7L2, ZNF174 |
| transcription regulatory region sequence-specific DNA binding | molecular function | NR5A2, ATF3, SOX9, NR5A1, NFE2L2, SOX2, SIN3A, TCF7, HDAC4, PER3, IKZF1, OVOL2, ZNF350, KLF4, DDIT3, SMARCA2, KLF9, TAF5, FOXJ1, ASH2L, PER1, AIRE, XRCC5, RFX5, CARM1, PSPC1, GATA5, DHX36, CALCOCO1, RCOR3, SFPQ, RFX3, SMAD4, GABPB2, TAF9B, XBP1, SNCA, RBBP5, ZNF568, ZNF746, BCOR, RNF10, NKX3-1, MACROH2A2, SOX18, SP4, CDK5RAP2, PRKN, EGR1, FOXA1, VSX1, ARID5B, MIDEAS, ZFHX4, KLF16, ZNF281, SOX12, KLF3, RUNX1, SP3, REST, TAF7, ZNF613, ZNF564, ZBTB20, KMT2D, ZBTB24, XRCC6, GATA3, RELA, MEF2C, PAX8, NONO, ZFHX3, CREB3L2, GLMP, PER2, ATF4, HMGA2, NFATC2, SP8, MTERF3, ZNF335, MEN1, HMGB1, MZF1, SMAD6, TFAP2A, SOX11, NFYC, CDK13, KLF12, KLF11, YY1, KMT2A, KDM3B, KLF14, NR1H4, SIX3, NFYA, BASP1, EGR3, ZNF217, MACROH2A1, EGR2, TFE3, SP2, KLF10, MEF2D, TAF2, FOXC2, RCOR1, POU2F2, SOX6, FOXK2, NFYB, YAP1, SOX4, KLF5, ZNF567, SUV39H2, GRHL1, LEF1, IKZF2, TBL1X, NCOR1, KLF7, FOS, NR1D1, FOXI1, SIX1, CREB3L3, RAI1, RCOR2, TRERF1, ZNF541, SIX2, MAFK, WNT11, GLI1, HNF4A, DLX5, GABPA, NFE2, SP6, KLF17, ZNF691, ZNF497, RFX6, Z |
| transcription termination site sequence-specific DNA binding | molecular function | SETX, XRN2 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | NR5A2, ESR1, PGR, AR, WT1, SOX9, HIF1A, HNF1A, CTCFL, ARNT2, NR3C1, STAT3, EBF2, OTX1, SOX2, MEF2A, TP63, MYC, PATZ1 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | molecular function | ZEB2, NFE2L2, PROP1 |
| transcriptional activator activity, RNA polymerase II transcription factor binding | molecular function | SOX10, CLOCK |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular function | TP53, ATF3, SOX9, HIF1A, NR1I2, HSF2, PLAGL1, DMRT1, STAT3, SOHLH1, GATA4, ETV5, SOHLH2, ETV2, SHOX, HOXD13, TCF7, IRX6, TFDP1, OVOL2, FOXJ3, KLF4, HOXD8, DDIT3, CEBPG, ISL1, E2F4, FOXJ1, NDN, AIRE, TBX10, NKX2-2, SPI1, PBX2, RFX5, ESRRG, NHLH1, ATMIN, ATF1, HOXD3, TFCP2, SMAD4, HNF4G, ZNF750, CREBRF, PHOX2B, TCF7L1, LHX3, EOMES, HOXA5, STAT5B, UBP1, ELF1, SOX18, PRDM2, CSRNP3, NEUROD6, CSRNP2, CREB3, NFATC1, HOXB5, EGR1, PBX3, FOSB, FOXA1, VEZF1, BATF, SPIC, EBF3, NFIB, BACH1, YBX1, HLTF, EBF4, FOXN1, SOX12, MAFG, DUX1, GCM2, NOTCH1, RUNX1, NFATC3, IER2, MSGN1, E2F3, MITF, GATA3, MSX1, RELA, MEF2C, PAX8, NFIA, TBR1, CREB3L2, BCL11B, FOXJ2, NKX6-3, ARID3C, MAF, ATF4, ELK1, HMGA2, NFATC2, HLF, MIXL1, MAFF, NR2E3, ZBED1, NFIC, ETS1, MZF1, ELK3, NR4A2, DBP, IRF5, E2F2, CEBPE, MEIS3, OVOL1, NKRF, ONECUT2, TFAP2A, ZNF24, SOX11, NFKB2, NHLH2, REL, NEUROD1, NFYC, PBX1, PAX5, ARID3B, NR1H4, TBX5, ARID3A, HOXC10, SIX3, HOXB7, NFYA, ELK4, EGR3, TEAD2, MLXIP, ZNF175, PLSCR1, EGR2, FOSL2, TFE3, POU3F3, TEAD1, HOXA7, ZNF1 |
| transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | molecular function | ATF3, HSF1, FOXO1 |
| transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding | molecular function | PROP1 |
| transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding | molecular function | ESX1, FOXO1, ZBTB5, SKIL, TCF7, IRX6, NR1D2, OVOL2, ZNF350, BCL11A, YBX3, MAX, LRRFIP1, ZC3H8, SPI1, IRX1, SARNP, ZBTB4, HOXA2, BCL6, SREBF2, NFX1, ZBTB6, GZF1, THAP1, PURA, PPARD, ZNF746, HBP1, PCBP3, MXD1, PRDM2, HES1, PHF6, JDP2, ASCL3, TCFL5, PRKN, NKX3-2, MYPOP, ASCL2, ZNF219, BACH1, ATF7, MXI1, ARID5B, HES6, KLF16, ZNF281, BHLHE40, SP3, NFATC3, REST, ZNF239, NACC2, SCRT1, ZBTB20, MITF, PRDM1, SKI, GATA3, MSX1, ZNF140, IRX4, RELA, ZFHX3, JARID2, NKX6-3, DEAF1, HMGA2, NFATC2, CC2D1B, ZBTB37, INSM2, FOXS1, ZNF205, NR2F6, MZF1, ELK3, ASCL1, PRRX1, BTG2, EMX2, HES7, IRX2, CGGBP1, CUX2, OVOL1, ZNF536, TFAP2A, SATB1, JPH2, BACH2, ZBTB32, KLF12, YY1, MECP2, ZNF224, INSM1, BCL6B, ZBTB26, MYT1L, ZNF175, ZNF217, E2F6, NR2C1, ZEB1, ETV3, SP2, ZNF85, IFI16, ZBTB2, BATF3, RCOR1, FOXP2, SOX6, FOXK2, ZFP90, ZBTB18, CHCHD3, DACH1, IRX5, MNT, HEY2, TBX3, ESRRA, NR1D1, IRX3, NFATC4, TGIF1, E4F1, HMBOX1, E2F7, HES4, ZBTB21, E2F8, MAFK, HIVEP1, GSC, IRF8, EN1, POU4F2, DMBX1, VAX2, PURG, TBX21, TFEC, ZBTB14, KLF8, MSX2, ERF, |
| transferase activity | molecular function | EGFR, AMHR2, TSSK4, TSSK6, AURKC, TERT, ERBB2, CDK1, GSTM1, NAT2, MGMT, FLT1, FGFR2, FGFR3, DNMT1, MAPK3, MAPK1, TYK2, WEE1, AXL, AKT1, KDR, GSK3B, UBE2B, ATM, EZH2, MTR, PANK2, DNMT3B, POLQ, GAPDH, GSTP1, PARP1, MGST1, FGFR1, PRPS2, CSNK2A2, ACAT1, GSTT1, MTOR, SULT1E1, BRSK2, GSTK1, KAT7, INSR, PGK2, YES1, IGF1R, KIT, SRC, FUT4, CHKA, PIK3CA, MAPK8, SULT1A1, POLG, ATR, BMPR2, DPY19L2, LMTK2, NSUN7, PARP2, CDC7, PDXK, RAF1, MAK, COMT, CLK3, CDK9, COX10, UAP1, CLOCK, PGK1, NTRK1, DDR1, ART3, CAMK4, MAST2, PPIP5K1, PRMT6, PRDM9, THG1L, PSAT1, CDY2A, CDY1, CKM, PCMT1, LIMK2, SULT2A1, DMPK, GAMT, MAPK14, ST6GALNAC6, PJA2, B4GALT2, GALT, PRPS1L1, RYK, TTC3, UBE2D3, ROR1, UBE3A, CAMK2B, CAMK2D, GK2, PDK4, UGP2, DGKK, IBA57, RNF20, SETD3, MARCHF3, TRIM69, SIAH1, METTL25, UBR7, CMAS, GLYATL1, RNF34, UBE2W, MOGAT1, ADPGK, WNK3, ALG2, TUT1, POLR1B, NMNAT1, NMRK1, HECW2, REV1, MKRN1, TBK1, MOK, TRIM17, NME7, ALG5, CEPT1, TRIM24, B4GAT1, LANCL1, REV3L, JAK2, RNGTT, B3GALNT1, PIAS1, UBR5, TYMS, PFKM, ST6GAL1, UGT2B7, SCP |
| transferase activity, transferring acyl groups | molecular function | NAT2, ACAT1, KAT7, CLOCK, CDY2A, CDY1, GLYATL1, MOGAT1, SCP2, NAA20, LCLAT1, MBOAT2, AGPAT1, LIPT1, NAT14, ZDHHC16, ZDHHC8, ABHD5, ZDHHC5, AGPAT2, SAT1, CPT1A, GLYAT, ZDHHC17, NCOA3, GNPAT, NAT1, GTF2B, SATL1, ZDHHC14, CREBBP, SAT2, DGAT2, ZDHHC6, ACAA1, TGM1, ACAA2, BAAT, ZDHHC23, NAT8L, PDHX, TGM5, HADHB, HGSNAT, PLAAT5, QPCTL, MCM3AP, NAA40, NAA50, HHAT, TGM7, DGAT1, NAA30, NAT16, ZDHHC19, SPTLC3, TAF1, SOAT1, CRAT, EP300, ZDHHC21, KMT2C, KAT5, AGPAT3, PNPLA3, CPT2, NCOA1, ESCO1, ATE1, ZDHHC11, NMT1, ZDHHC20, PLA2G15, GPAM, ZDHHC3, ZDHHC2, SPTLC1, TGM4, QPCT, ZDHHC13, NAA80, AGPAT4, HAT1, GCAT, TGM2, OSGEP, HHATL, NAT8, SPTLC2, CIITA, GPAT3, DGAT2L6, PIGW, GNPNAT1, ELP3, ZDHHC7, TGM6, MOGAT2, ZDHHC24, KAT2A, CASD1, ZDHHC4, DLAT, NAA10, LPCAT2, LPCAT1, KAT6A, GGT7, GGT1, CHAT, LPCAT3, CPT1C, KAT2B, ALAS1, AANAT, LPCAT4, MOGAT3, CPT1B, TGM3, ASPG, ZDHHC22, ZDHHC12, NMT2, DLST, KAT6B, MBOAT7, NAT10, NAA60, ZDHHC18, LCAT, GTF3C4, ZDHHC1, OXSM |
| transferase activity, transferring acyl groups other than amino-acyl groups | molecular function | ACAT1, KAT7, MOGAT1, SCP2, ELOVL6, DGAT2, ACAA1, ACAA2, HADHB, ELOVL2, NAT16, OSGEP, DGAT2L6, MOGAT2, MOGAT3, ASPG, OXSM |
| transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer | molecular function | ACLY, CS |
| transferase activity, transferring alkyl or aryl (other than methyl) groups | molecular function | FDFT1, UBIAD1, NUS1 |
| transferase activity, transferring glycosyl groups | molecular function | PARP1, FUT4, DPY19L2, PARP2, ART3, GALNTL5, ST6GALNAC6, B4GALT2, ALG2, ALG5, B4GAT1, B3GALNT1, ST6GAL1, UGT2B7, GLT8D1, OGT, UGT2B10, PIGA, GYG1, EXT1, B4GALT4, GYS2, B4GALNT1, GALNT2, POMGNT2, UGT1A8, FUT6, CHSY1, LARGE2, STT3B, ALG8, EXTL2, TNKS, PIGH, ALG10, B3GALNT2, ART4, MGAT4C, MGAT4A, B3GALT2, UGT2B11, GBE1, DPY19L1, B3GLCT, EXTL1, DPAGT1, B4GALT3, PNP, UGT1A4, B3GALT6, UGT2B28, PIGM, LARGE1, STT3A, PIGP, PARP14, XYLT2, ST6GALNAC4, PIGV, AGL, NAMPT, FUT5, UPP1, TIPARP, GALNT13, HAS2, GLT8D2, GYG2, MGAT5B, ALG10B, B3GNTL1, GALNT5, XYLT1, GCNT2, GALNT16, POFUT2, PARP3, APRT, GXYLT1, POGLUT3, GLT6D1, GALNT4, PARP16, ST8SIA2, ST8SIA4, ST6GAL2, FUT8, A4GALT, MFNG, GLT1D1, TNKS2, ST6GALNAC2, GALNT10, GALNT15, PIGB, B3GALT1, UGT2B15, DPY19L3, DPY19L4, B4GALT6, GCNT1, B3GNT5, GBA2, HPRT1, B4GALT1, GALNT1, PARP6, ALG13, COLGALT2, C1GALT1, B3GALT5, B4GALT5, UGT2B4, UGT2A3, CHPF, ST8SIA1, EXT2, ALG1, GALNT8, UGGT1, PYGL, PYGB, ST3GAL4, GALNT18, POGLUT1, GALNT11, POMGNT1, FUT9, HAS3, PLOD3, UGT2B17, TYMP, PPAT, F |
| transferase activity, transferring hexosyl groups | molecular function | B3GALNT1, B4GALNT1, ALG8, B3GALNT2, B3GALT2, B3GALT6, GLT6D1, A4GALT, B3GALT1, B3GNT5, ALG13, B3GALT5, B3GNT3, ABO, B3GNT8, B3GNT4, B3GNT6, B3GNT9, B3GNT7, B4GALNT2 |
| transferase activity, transferring pentosyl groups | molecular function | QTRT2, PNP, UPP1, TYMP, MTAP, QPRT, QTRT1, UPP2 |
| transferase activity, transferring phosphorus-containing groups | molecular function | CKM, CKMT2, PIGO, FCSK, CDS1, CKB |
| transferase activity, transferring selenium-containing groups | molecular function | SEPSECS |
| transferrin receptor activity | molecular function | TFRC, TFR2 |
| transferrin receptor binding | molecular function | TF, HFE, SNX2, CD81, SNX4, RGMA, HJV, IKBKG, IKBKB |
| transforming growth factor beta binding | molecular function | TGFB3, TGFBR3, ITGAV, LTBP1, CD93, ACVR1, THBS1, LRRC32, SPINT3, TWSG1, TGFBR1, HYAL2, WFIKKN2, TGFBR2, LTBP3, CD109, NRROS, WFIKKN1, ENG, ACVRL1, VASN, LTBP4, CD36 |
| transforming growth factor beta receptor activity, type I | molecular function | ACVR1, BMPR1A, TGFBR1, ACVRL1 |
| transforming growth factor beta receptor activity, type II | molecular function | AMHR2, TGFBR2 |
| transforming growth factor beta receptor activity, type III | molecular function | TGFBR3 |
| transforming growth factor beta receptor binding | molecular function | TGFB1, AMH, INHBA, TGFB3, NODAL, BMP7, TGFBR3, GDF15, GDF9, BMP15, BMP4, INHA, RASL11B, TGFB2, LEFTY1, LRG1, SMAD2, USP15, TGFBRAP1, SMURF2, INHBC, LEFTY2, SMAD3 |
| transforming growth factor beta-activated receptor activity | molecular function | TGFBR3, LTBP1, TGFBR1, TGFBR2, ENG, ACVRL1, LTBP4 |
| transition metal ion binding | molecular function | APP, TCHHL1, S100A4, S100A5, APLP2, FLG, RIDA, S100P, S100A7, HRNR, S100G, APLP1 |
| transition metal ion transmembrane transporter activity | molecular function | SLC11A1 |
| transketolase activity | molecular function | TKTL1, TKTL2, TKT |
| translation activator activity | molecular function | DAZ1, DAZL, PABPC1, BOLL, PAIP1, RPS27L, DHX29, CTIF, LARP1, ABCF1, MIF4GD, C1QBP |
| translation elongation factor activity | molecular function | EEF1G, EEF1A1, GFM1, EIF5A, EIF5A2, GTPBP1, EEF2, EFL1, EEF1D, EEF1A2, GFM2, TSFM, TUFM, EEF1B2, EEFSEC, ABTB1, GTPBP2 |
| translation factor activity, non-nucleic acid binding | molecular function | NEURL1 |
| translation factor activity, RNA binding | molecular function | EIF4G2, EEF2K, EIF2S2, EIF1, EIF2S3, EIF2B3, EIF4A1, GCN1, MTIF3, CPEB4, EEF1D, CPEB1, EIF4E2, EEF1A2, CPEB2, CPEB3, EIF1AX, ABCF1, EIF4H |
| translation initiation factor binding | molecular function | FMR1, DDX3X, EIF3F, EIF2S2, EIF3M, POLR2G, POLR2D, EIF3B, TRIM32, EIF4EBP1, EIF3C, RPS24, GLE1, ZPR1, LARP1, GCH1, TBL2, EIF2B5, EIF2B4, LIN28A |
| translation regulator activity | molecular function | RPS14, ZCCHC13, IGF2BP2, AIRE, FXR1, RPS9, AARS1, CPEB4, EIF4E, CPEB1, FXR2, RPL10, CYFIP1, CPEB2, CPEB3, IGF2BP3, PKP3, EIF4A3, IGF2BP1 |
| translation release factor activity | molecular function | GSPT1, ETF1, MRPL58, GSPT2, MTRF1L, MTRF1, C12orf65 |
| translation release factor activity, codon nonspecific | molecular function | MRPL58 |
| translation release factor activity, codon specific | molecular function | ETF1, MTRF1L, MTRF1 |
| translation repressor activity | molecular function | FMR1, NANOS1, EIF4EBP2, IREB2, EIF4EBP1, SAMD4A, TRIM71, SAMD4B |
| translation repressor activity, mRNA regulatory element binding | molecular function | TYMS, SHMT1, PURA, ZNF540, CPEB4, CPEB1, CELF4, DHFR, CPEB2, CPEB3, RARA |
| translation termination factor activity | molecular function | ETF1 |
| transmembrane receptor protein serine/threonine kinase activity | molecular function | AMHR2, BMPR2, ACVR1B, ACVR1, BMPR1A, ACVR2B, ACVR1C, TGFBR1, ACVR2A, TGFBR2, ACVRL1 |
| transmembrane receptor protein tyrosine kinase activator activity | molecular function | EGF, NRG1, NRG3, EFNA5, ANGPT4, DGKQ, GREM1 |
| transmembrane receptor protein tyrosine kinase activity | molecular function | EGFR, ERBB2, FLT1, FGFR2, FGFR3, AXL, KDR, FGFR1, INSR, IGF1R, KIT, NTRK1, DDR1, RYK, ROR1, ALK, LTK, EPHB2, TIE1, FLT4, ROS1, TEK, NTRK2, EPHB1, EPHA6, EPHA4, EPHA1, ERBB3, RET, PDGFRB, EPHA2, EPHA7, MST1R, PDGFRA, EPHA3, EPHA8, FGFR4, CSF1R, INSRR, EPHB3, EPHB4, ROR2, EPHA10, MERTK, EPHB6, TYRO3 |
| transmembrane receptor protein tyrosine kinase adaptor activity | molecular function | SH2B3, PIK3R1, SHC1, STAP1, IRS1, GAB2, FRS2, TRADD, DOK2, SH2B2, TRAT1 |
| transmembrane receptor protein tyrosine phosphatase activity | molecular function | PTPRR, PTPRF, PTPRA, PTPN6, PTPRG, PTPRT, PTPRC, PTPRB, PTPRM, PTPRN2, PTPRU, PTPRE, PTPRO, PTPRZ1, PTPRH, PTPRD |
| transmembrane signaling receptor activity | molecular function | EGFR, ICAM1, FAS, ERBB2, KIR2DS2, TLR4, TLR2, LEPR, CD79A, CD69, GABRB1, RYK, OR12D2, ANTXR1, SIGLEC8, CHRNA5, FZD9, GP1BB, LMBR1, TNFRSF10C, ADGRL1, CD79B, GABRA2, CHRNE, ADGRA2, LGR4, FZD8, FZD4, HTR3B, IL1R1, HTR3A, OR1G1, PTH1R, CALCRL, BCAM, SCARB2, GP6, OR52A1, THBD, KLRC1, NRXN1, OR1L6, M6PR, FZD2, OR1N2, TNFRSF10D, OR10J1, FCGR2B, NOTCH1, OR1D5, ANTXR2, EBP, CHRNA2, SEMA4D, FZD3, CLEC2D, FCER1A, GABRG2, MRC1, KLRC2, GABRB3, CD300C, OR4X1, OR4C12, NRXN2, MARCO, GLRA3, CHRNB1, GABRA5, GIPR, GHRHR, KLRC3, TLR1, TLR10, FZD7, CHRNA7, GCGR, CHRND, CHRFAM7A, ADGRF1, ADGRA3, ADGRF4, OR4D11, FCRL2, SMO, CHRNA10, CELSR2, CELSR1, CLEC1B, ANTXRL, CD3E, TNFRSF8, DCC, GABRB2, GABRA4, C17orf99, GABRG1, FCRL4, LYVE1, ADGRB3, IGSF6, CD3G, EPOR, CHRNA3, GLP1R, CD247, IL21R, GPR182, OR7C2, ADGRL2, ADGRV1, GPR157, GABRP, NPC1, FCGR3B, CR2, OR3A1, SORL1, INTS6, GABRD, ADGRB2, OR2A4, OR1E1, CRHR1, CRHR2, LMBR1L, SLC22A17, ADGRE3, HTR3E, P2RX6, ERBB3, EVI2A, GLRA1, PTH2R, CHRNA6, TLR9, GABBR1, ADGRB1, OR7C1, GLP2R, CD4, FCG |
| transmembrane transporter activity | molecular function | GJA1, SLC22A5, MT-ATP6, MT-ATP8, SLC35E2B, SLC2A5, TMEM241, SLC5A8, SLC35B3, FLVCR2, SLC2A3, SLC25A4, SLC35B1, SLC49A3, CNNM2, SLC22A2, SLC12A2, SLC44A4, SLC15A4, SLC35D1, SLC17A3, SLC16A5, SLC44A3, SLC44A5, SLC44A1, SLCO1B3, FLVCR1, RALBP1, MFSD14A, ABCA12, SLC41A1, SLC22A15, SLC22A12, SLC22A23, CLCN7, SLC15A2, SLC35F1, MFSD4B, SLC35D2, SLC22A9, SLC7A6, SLC47A1, ABCC3, SLC25A6, SLC13A2, SLC5A12, SVOPL, SLC7A3, SFXN1, SLC17A5, SLC12A6, SLC25A5, SLC18A3, OSCP1, SLC2A10, SLC17A1, MFSD8, SLC7A8, MFSD10, CNNM4, SLC16A14, SLC22A24, SLCO5A1, SLC12A4, UCP1, SLC7A9, SLC47A2, SLC37A3, ABCC9, SLC2A13, SLC13A1, SLC17A6, SLC22A7, SLCO1A2, SV2C, SLCO4C1, SLC22A16, SLC16A10, ABCB9, SLC7A14, SLC25A31, MFSD1, SLC23A3, SLC16A9, SLC46A3, SLC2A14, SLC2A8, SLC22A13, SLC37A4, SLC7A1, SFXN3, SLC2A11, ATP8A1, SLC35E2A, SLC2A4, SLC16A13, SLC22A17, AQP1, SLC37A1, SLC35E4, SPNS3, CNNM3, SLCO2A1, SLC12A9, SLC23A1, SLC7A7, SLC12A7, SLC43A1, SLC16A8, SLC5A1, SLC5A7, SLC22A4, SLC12A5, SLC5A6, SLC5A2, CLCN6, SLC16A1, SV2B, SLC35F2, SLC35F6 |
| transmembrane-ephrin receptor activity | molecular function | EPHB2, EPHB1, EPHA6, EPHA4, EPHA1, EPHA2, EPHA7, EFNB3, EPHA3, EPHA8, EPHA10, EFNA3 |
| transmitter-gated ion channel activity | molecular function | GLRA3, GLRA1, GLRA2 |
| transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | molecular function | GABRB1, GABRA2, CHRNE, GRIN1, GABRG2, GABRB3, CHRNB1, GABRA5, CHRND, CHRNA10, GABRB2, GABRA4, GABRG1, GRIA2, GRIN2C, GRIK3, GRIK5, GRIN2B, GABRD, GLRA1, GRIN3A, GRID2, GABRR2, GRIA3, GRIK4, GABRA1, GRIN2A, GRIN3B, CHRNB2, GABRA3, GRIA1, GRID1, GRIN2D, GRIK1, GRIK2, GABRG3, CHRNA1, GLRA2, CHRNB4 |
| transporter activity | molecular function | ABCB1, ABCC1, IGF2R, PTGDS, SLC22A18, AQP5, SLC13A3, SLC22A5, AQP7, SLC26A3, NUP88, UCP3, ABCA4, SCARB1, SEC22A, SYN1, GABRA5, PACSIN2, CDH17, CPNE1, IPO7, ATP6V1C1, NUP98, TCOF1, ATP6V0B, OCA2, CPNE6, FXYD2, TCIRG1, ABCC6, CPNE7, ABCB11, STEAP1 |
| transposase activity | molecular function | THAP10, THAP9, PGBD5 |
| triacyl lipopeptide binding | molecular function | TLR2 |
| tricarboxylic acid transmembrane transporter activity | molecular function | SLC25A1, SLC13A5 |
| triglyceride binding | molecular function | LPL, CETP |
| triglyceride lipase activity | molecular function | LIPE, LIPF, LPL, CES4A, ABHD5, CES1, LIPG, AADAC, LIPC, DDHD2, LIPH, PNPLA3, PNPLA4, DAGLB, PNLIPRP2, PNLIPRP1, PLA1A, PNPLA1, PNLIP, PNPLA5 |
| triglyceride transfer activity | molecular function | MTTP |
| trimethylamine monooxygenase activity | molecular function | FMO3 |
| trimethylamine receptor activity | molecular function | TAAR5 |
| trimethyllysine dioxygenase activity | molecular function | TMLHE |
| triokinase activity | molecular function | TKFC |
| triose-phosphate isomerase activity | molecular function | TPI1 |
| tripeptide transmembrane transporter activity | molecular function | SLC15A1 |
| tripeptidyl-peptidase activity | molecular function | ACE, TPP1, TPP2 |
| triphosphatase activity | molecular function | RNGTT |
| triphosphoric monoester hydrolase activity | molecular function | SAMHD1 |
| triplex DNA binding | molecular function | DDX11 |
| tRNA (adenine-N1-)-methyltransferase activity | molecular function | TRMT61A, TRMT10C, TRMT61B |
| tRNA (cytosine) methyltransferase activity | molecular function | METTL2A, METTL2B |
| tRNA (cytosine-2'-O-)-methyltransferase activity | molecular function | FTSJ1 |
| tRNA (cytosine-3-)-methyltransferase activity | molecular function | METTL2A, METTL2B, METTL6 |
| tRNA (cytosine-5-)-methyltransferase activity | molecular function | NSUN2, NSUN6, NSUN3, TRDMT1 |
| tRNA (guanine(37)-N(1))-methyltransferase activity | molecular function | TRMT5 |
| tRNA (guanine(9)-N(1))-methyltransferase activity | molecular function | TRMT10C, TRMT10A |
| tRNA (guanine) methyltransferase activity | molecular function | THUMPD2, THUMPD3 |
| tRNA (guanine-N1-)-methyltransferase activity | molecular function | TRMT5, TRMT10C, TRMT10A |
| tRNA (guanine-N2-)-methyltransferase activity | molecular function | TRMT1L, TRMT1 |
| tRNA (guanosine-2'-O-)-methyltransferase activity | molecular function | FTSJ1 |
| tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase | molecular function | CDKAL1 |
| tRNA (uracil) methyltransferase activity | molecular function | TRMT44, TRMT9B, ALKBH8 |
| tRNA 2'-O-methyltransferase activity | molecular function | TRMT13 |
| tRNA 2'-phosphotransferase activity | molecular function | TRPT1 |
| tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity | molecular function | TRMT12 |
| tRNA binding | molecular function | TERT, THG1L, FARS2, EEF1A1, YRDC, KARS1, MARS1, NSUN2, TRNT1, RPL35A, IARS1, EIF2A, PTCD1, SSB, YARS1, NSUN6, DTD2, CARS1, RARS1, DARS2, SARS2, IARS2, NEMF, TARS1, DTD1, AARS1, AARS2, TRMT10C, SLFN11, SEPSECS, NSUN3, TRNAU1AP, MRPS27, XPOT, ELP1, SARS1, PSTK, AIMP1, TRMT1L, TRMU, HSD17B10, TRMT10A, ELP3, TYW5, CTU1, ALKBH8, ALKBH1, TRMT1, FARSA, CTU2, EEFSEC, IGHMBP2, EARS2, NAT10 |
| tRNA demethylase activity | molecular function | ALKBH1 |
| tRNA dihydrouridine synthase activity | molecular function | DUS1L, DUS2, DUS3L |
| tRNA dimethylallyltransferase activity | molecular function | TRIT1 |
| tRNA guanylyltransferase activity | molecular function | THG1L |
| tRNA methyltransferase activity | molecular function | TRMT5, TYW3, TRMT13, TRMT12, FTSJ1, TRMT9B, TRDMT1, LCMT2 |
| tRNA pseudouridine synthase activity | molecular function | PUS10, PUS3 |
| tRNA-4-demethylwyosine synthase activity | molecular function | TYW1B, TYW1 |
| tRNA-dihydrouridine20 synthase activity | molecular function | DUS2 |
| tRNA-intron endonuclease activity | molecular function | TSEN2 |
| tRNA-specific adenosine deaminase activity | molecular function | ADAT1, ADARB1, ADAR, ADAD2, ADARB2 |
| tRNA-specific adenosine-34 deaminase activity | molecular function | ADAT3 |
| tRNA-specific ribonuclease activity | molecular function | ELAC2 |
| tRNA-uridine aminocarboxypropyltransferase activity | molecular function | DTWD1 |
| tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity | molecular function | TYW5 |
| tropomyosin binding | molecular function | S100A6, CALD1, NEBL, TMOD3, PYCARD, TMOD4, TNNT1, LMOD2, TMOD1, TNNT3, LMOD1, SMTNL1 |
| troponin C binding | molecular function | TNNT3 |
| troponin I binding | molecular function | TNNI3K, RCAN3, TNNT3 |
| troponin T binding | molecular function | TNNI2, TNNT1 |
| tryptamine:oxygen oxidoreductase (deaminating) activity | molecular function | AOC2, AOC3 |
| tryptophan 2,3-dioxygenase activity | molecular function | IDO2, IDO1 |
| tryptophan 5-monooxygenase activity | molecular function | TPH1, TPH2 |
| tryptophan-tRNA ligase activity | molecular function | WARS1 |
| TSC1-TSC2 complex binding | molecular function | WDR45B |
| tubulin binding | molecular function | BRCA1, BIRC5, PRNP, AGBL4, BCCIP, STMND1, DYRK1A, TPPP3, VBP1, RPS3, TPPP2, KIF14, TTLL7, TPGS1, PHF6, CDK5RAP2, RABGAP1, PRKN, MAP4, TTLL1, STMN1, TBCC, STMN3, HDGF, ALDOA, TTLL6, AGBL5, TTLL2, CACYBP, TBCA, UNC5C, MAP2, TTLL4, CLIP1, MAP1S, TTLL11, RITA1, NUMA1, TTLL9, GPAA1, TPR, HDGFL3, EML2, TTLL12, EML1, DAG1, PRUNE1, NCALD, TPPP, AGBL1, MAP1B, LRRK2, MAP7D3, IFT81, SGIP1 |
| tubulin deacetylase activity | molecular function | SIRT2, HDAC6 |
| tubulin-dependent ATPase activity | molecular function | KIF18A |
| tubulin-glutamic acid ligase activity | molecular function | TTLL7, TPGS1, TTLL1, TTLL6, TTLL2, TTLL4, TTLL11, TTLL9 |
| tubulin-tyrosine ligase activity | molecular function | TTL, TTLL12 |
| tumor necrosis factor binding | molecular function | TNFRSF1A, A2M, TMC8, TRAF2 |
| tumor necrosis factor receptor binding | molecular function | TNF, TNFSF10, STAT1, FASLG, CASP8, TNFSF15, TRIM37, TNFSF12, LTB, TRAF3, BABAM2, FADD, TNFSF13B, TRAF6, TRAF4, TNFSF4, TRAP1, TRADD, TRAF5, TNFSF14, EDA, SIVA1, TNFSF8, TNFSF9, TRAF1, TRAF2, TNFSF13, LTA |
| tumor necrosis factor receptor superfamily binding | molecular function | TNFSF10, FADD, TNFSF4, TNFSF9 |
| tumor necrosis factor-activated receptor activity | molecular function | TNFRSF1A, TNFRSF1B, FAS, TNFRSF25, TNFRSF19, TNFRSF4, TNFRSF14, TNFRSF18, TNFRSF11A, EDA2R |
| type 1 angiotensin receptor binding | molecular function | TYK2, JAK2, ARAP1, BDKRB2, EDNRB, ARRB2, AGT |
| type 1 cannabinoid receptor binding | molecular function | CNRIP1 |
| type 1 fibroblast growth factor receptor binding | molecular function | FGF17, FGF8, NPTN, NRXN1, FGF23, FGF18 |
| type 1 galanin receptor binding | molecular function | GAL |
| type 1 hypocretin receptor binding | molecular function | HCRT |
| type 1 melanin-concentrating hormone receptor binding | molecular function | PMCH |
| type 1 melanocortin receptor binding | molecular function | MRAP2, POMC |
| type 1 metabotropic glutamate receptor binding | molecular function | ESR1, DNM3 |
| type 1 neuromedin U receptor binding | molecular function | NMU |
| type 2 angiotensin receptor binding | molecular function | AGT |
| type 2 fibroblast growth factor receptor binding | molecular function | FGF17, FGF8, FGF18, FGF10 |
| type 2 galanin receptor binding | molecular function | GAL |
| type 2 hypocretin receptor binding | molecular function | HCRT |
| type 2 metabotropic glutamate receptor binding | molecular function | SLC9A3R1, SLC9A3R2 |
| type 2 neuromedin U receptor binding | molecular function | NMU |
| type 2A serotonin receptor binding | molecular function | GNA11, GNAQ, ARRB2 |
| type 3 galanin receptor binding | molecular function | GAL |
| type 3 melanocortin receptor binding | molecular function | ASIP, MRAP2, POMC |
| type 3 metabotropic glutamate receptor binding | molecular function | SLC9A3R1, CALM3, SLC9A3R2 |
| type 4 melanocortin receptor binding | molecular function | ASIP, MRAP2, POMC |
| type 5 melanocortin receptor binding | molecular function | MRAP2 |
| type 5 metabotropic glutamate receptor binding | molecular function | PRNP, DNM3, ADORA2A, NECAB2 |
| type I activin receptor binding | molecular function | NODAL, SMAD6 |
| type I interferon binding | molecular function | IFNAR2, IFNAR1 |
| type I interferon receptor activity | molecular function | IFNAR2, IFNAR1 |
| type I interferon receptor binding | molecular function | IFNA1, IFNA8, IFNA10, IFNA2, IFNA14, IFNW1 |
| type I transforming growth factor beta receptor binding | molecular function | TGFB1, TGFB3, SMAD6, SMAD2, TGFBR2, ENG, SNX25 |
| type II activin receptor binding | molecular function | INHBA, MAGI2 |
| type II transforming growth factor beta receptor binding | molecular function | TGFB1, TGFB3, TGFBR3, BAMBI, TGFB2, TGFBR1, ENG |
| type III transforming growth factor beta receptor binding | molecular function | TGFB1, TGFB3, TGFB2, TGFBR2 |
| tyrosine 3-monooxygenase activator activity | molecular function | PARK7 |
| tyrosine 3-monooxygenase activity | molecular function | TH |
| tyrosine binding | molecular function | GPR143 |
| tyrosine-tRNA ligase activity | molecular function | YARS1 |
| tyrosyl-RNA phosphodiesterase activity | molecular function | TDP2 |
| U1 snRNA binding | molecular function | SNRNP70, COIL, SNRPB2, ISG20, SNRPC, GEMIN5, PRPF8, RBMXL3, SNRPA |
| U1 snRNP binding | molecular function | SNRPC, SNRPB, SNRPD1, SNRPA |
| U12 snRNA binding | molecular function | RNPC3 |
| U2 snRNA binding | molecular function | RO60, COIL, ISG20, PRPF8, SNRPA1 |
| U2 snRNP binding | molecular function | SNRPB |
| U3 snoRNA binding | molecular function | XRCC5, ISG20, SNU13, PRKDC, TSR1, DHX37, DIEXF, TBL3, BMS1 |
| U4 snRNA binding | molecular function | DDX39B, SART3, PRPF31, SNU13, GEMIN5, PRPF4 |
| U4atac snRNA binding | molecular function | PRPF31, SNU13, GEMIN5 |
| U5 snRNA binding | molecular function | PRPF8, EFTUD2 |
| U6 snRNA (adenine-(43)-N(6))-methyltransferase activity | molecular function | METTL16 |
| U6 snRNA 3'-end binding | molecular function | LSM3, METTL16 |
| U6 snRNA binding | molecular function | TUT1, RBM22, DDX39B, EIF5A, SART3, PRPF8, LSM8, LSM7, LSM2, LSM4, PRPF4 |
| U6atac snRNA binding | molecular function | SART3 |
| U7 snRNA binding | molecular function | LSM11 |
| ubiquinol-cytochrome-c reductase activity | molecular function | MT-CYB, UQCRFS1, UQCR11, UQCRQ, UQCRHL, UQCRC1, UQCR10, UQCRH |
| ubiquinone binding | molecular function | SDHB, ETFDH, COQ10B, SDHD, DHODH |
| ubiquitin activating enzyme activity | molecular function | UBA6, SAE1 |
| ubiquitin binding | molecular function | HSPB1, TOP2A, NBR1, UBR5, CXCR4, USP13, TSG101, BUB3, RNF168, VPS28, USP16, FBXW7, FAF2, UBE2N, MARCHF7, NUP62, CKS1B, VPS36, PRKN, FAAP20, UBXN2A, OTULINL, UBAP1, UBXN7, TRIM32, SIRT2, ZFAND2B, NEDD4, RAE1, ILRUN, GGA3, SQSTM1, USP33, WDR92, BIRC2, ADRM1, OTUB2, NSFL1C, TOLLIP, SHARPIN, USPL1, UBXN2B, RNF19B, RBCK1, TOM1L1, WDR48, USP25, UBE2L6, RNFT1, RNF185, FAF1, HDAC6, MVB12A, PLAA, SPRTN, AUP1, FBXO7, DNAJB2, CKS2, RNF31, UBXN11, MARK4, ASCC2, MVB12B, SMAD3, NPLOC4, UBXN1, UCHL1, USP5 |
| ubiquitin conjugating enzyme activity | molecular function | UBE2B, UBE2D3, UBE2W, UBE3C, UBE2R2, UBE3B, UBE2Q2, AKTIP, UBE2N, UBE2G1, UBE2Q1, UBE2H, UBE2NL, UBE2E3, UBE2D4, UBE2Z, UBE2U, TAF1, UBE2L3, UBE2V1, UBE2T, UBE2E2, CDC34, UBE2V2, UBE2J2, UBE2F, BIRC6, UBE2L6, UBE2D1, UBE2E1, UBE2K, UBE2M, UBE2C, UBE2QL1, UBE2O, UBE2S |
| ubiquitin conjugating enzyme binding | molecular function | RNF114, SIAH1, ZMYM2, DCUN1D1, DCUN1D4, RNF19A, SIAH2, RNF14, ARIH1, RNF144B, MARCHF7, ARIH2, RASD2, PRKN, RNF217, ANKIB1, DCUN1D5, SIAH3, TOLLIP, RNF19B, TRAF6, RNF40, MARCHF6, RNF144A, AUP1, FOXL2, RNF125, PPARA, TRIM72, GRIK2, DCUN1D2, UBE3D |
| ubiquitin ligase activator activity | molecular function | FZR1, BTRC, CDC20B |
| ubiquitin ligase inhibitor activity | molecular function | RPL5, RPS7, RPL11, RPL23 |
| ubiquitin ligase-substrate adaptor activity | molecular function | SKP1, BTRC, ARRDC4, HERPUD1, PDCD6, DET1, ARRDC1, SPSB1, VHL, SPSB2, FBXO7, PEF1, ARRDC5, SPSB4 |
| ubiquitin modification-dependent histone binding | molecular function | DNAJC2, TP53BP1, USP15 |
| ubiquitin protein ligase activity | molecular function | RAG1, UBE2B, MDM2, UBR2, CDC42, RNF114, PJA2, MED7, UBE3A, TRIM69, SIAH1, UBR7, RNF34, HECW2, MKRN1, TRIM17, TRIM24, UBR5, TRIP12, UBE3C, TRIM74, ZNRF2, ASB12, ITCH, RNF26, TRIM4, TRIM13, XIAP, BRAP, RNF149, COP1, RNF183, TRIM39, RNF19A, PRPF19, SIAH2, LTN1, NFX1, TRIM25, FBXL22, HUWE1, DTX3L, FBXO17, PELI1, RNF14, BTRC, ARIH1, TRIM37, MEX3C, RNF144B, RNF10, TRIM58, TRIM11, IRF2BPL, TRIM3, NEURL1, ARIH2, RBBP6, DZIP3, CBLL2, CHFR, NEURL4, TRIM9, TRIM2, RNF41, FBXO2, PRKN, TRIM61, TRIM68, RNF217, RNF138, TRIM44, TRIM15, RNF167, ANKIB1, HLTF, BIRC7, FBXO4, STUB1, MED21, BSPRY, RFWD3, SH3RF1, FBXO30, C10orf90, MED10, FANCL, RNF6, TRIM64, TRIM32, UBR4, RNF43, RNF135, GID4, RNF170, PELI2, MGRN1, NEDD4, TRIM40, DTX1, UBR1, PJA1, SH3RF3, RC3H2, CCNB1IP1, MARCHF5, TRIM10, RNF150, RNF175, MED31, BIRC2, RNF151, UBR3, ZNRF4, UHRF2, RLIM, TRIM49C, SKP2, SIAH3, MYLIP, ANAPC11, FBXO40, NOSIP, TMEM129, RNF103, TRIM38, RNF187, RC3H1, RNF165, NEDD4L, RNF11, WWP2, RNF13, CBL, RNF19B, RNF111, TRIM59, HACE1, RNF139, RCHY1, RNF15 |
| ubiquitin protein ligase binding | molecular function | EGFR, TP53, BCL2, TNFRSF1B, BRCA1, HIF1A, GSK3B, UBE2B, MDM2, CASP8, CLU, CBS, HSPA9, BAG6, RB1, HSPA5, SLC22A18, HSPA1A, HSPA1B, HSPD1, HSPA1L, SUMO1, FOXO1, DNM1L, WFS1, RNF8, RANGAP1, PACRG, HSPA8, RPL5, PER3, UBE2D3, RNF20, SLF2, RNF34, UBE2W, ERLIN1, PIAS1, CXCR4, CACUL1, USP13, TSG101, MAP1LC3A, SNCAIP, PER1, XRCC5, PRKAR2A, RPA2, CAMLG, RPL11, CUL9, TRIB3, PSMD1, TXNIP, RTN4, BCL10, ACVR1B, PXN, CCT2, LAPTM4B, FBXW7, FAF2, DERL1, BLZF1, FZD8, FZD4, STX8, ARIH1, PIAS2, TRIM37, RALA, XBP1, TCP1, MAGEA2, UBE2N, SUMO2, UBE2G1, RPS27A, ZNF746, KDM4A, PRKACB, TMBIM6, KCNH2, NAE1, JKAMP, CASC3, PRKN, NDUFS2, BAG4, TRAF3, CUL1, RRAGA, ABI2, PPARGC1A, HLTF, BAG5, STUB1, SLC25A5, PRDX6, CCDC50, WRAP53, FANCL, UBE2D4, UBXN7, SKI, FHIT, YWHAZ, RELA, IKBKE, NEDD8, TRIB1, DTX1, HM13, PTPN22, AXIN1, ISG15, NFKBIA, ATXN3, BID, SQSTM1, TANK, CUL5, PINK1, SNX9, SMAD6, USP2, TUBB, PRR5L, CACYBP, IKBKG, SPOP, EIF4E2, RALB, JAK1, APC, LRPPRC, YWHAE, UBE2L3, ELOB, DET1, SPART, TOLLIP, UBE2T, MFN2, TPI1, CUL2, BECN1, NLK, GP |
| ubiquitin-dependent protein binding | molecular function | FAN1, FAAP20, ANKRD13A, IDE, ANKRD13B, DNAJB2, ANKRD13D |
| ubiquitin-like modifier activating enzyme activity | molecular function | MOCS3, NAE1, UBA7, UBA2, UBA3, UBA5, UBA6, SAE1 |
| ubiquitin-like protein binding | molecular function | DCUN1D1, DCUN1D4, DCUN1D5, DCUN1D2 |
| ubiquitin-like protein conjugating enzyme binding | molecular function | PARK7, TCERG1, RPS3, UBA2, RNF185, UBE3D |
| ubiquitin-like protein ligase binding | molecular function | USP13, ITCH, DTX3L, CDK5RAP3, HGS, STAM, TRIP4, STAT2, H2BC9, UBE2C, DDRGK1, PRR7 |
| ubiquitin-like protein-specific protease activity | molecular function | SENP5, OTULINL, USP25 |
| ubiquitin-protein transferase activator activity | molecular function | CDC20, FBXW7, FZR1, CBX8, CDC20B, UBE2L3, AUP1, RING1 |
| ubiquitin-protein transferase activity | molecular function | RAG1, BRCA1, BIRC5, UBE2B, MDM2, UBR2, RNF114, RNF8, KLHL10, MALT1, PJA2, TTC3, UBE2D3, UBE3A, RNF20, MARCHF3, TRIM69, SIAH1, RNF34, UBE2W, HECW2, TRIM17, TRIM24, UBR5, UBE4A, TRIP12, UBE3C, FBXO11, MIB1, ITCH, TRIM13, CNOT4, XIAP, BRAP, RNF168, COP1, ZFP91, RNF19A, MAGEL2, CDC23, FBXL5, PRPF19, SIAH2, LTN1, UBE2R2, UBE3B, HUWE1, DTX3L, UBE2Q2, PELI1, RNF14, BTRC, ARIH1, TRIM37, UBE2N, UBE2G1, TNFAIP1, HERC4, BCOR, RNF144B, TRIM11, FBXO9, TRIM3, NEURL1, ARIH2, RBBP6, DZIP3, KCTD13, DDB2, CHFR, TRIM2, RNF41, DTL, FBXO2, FBXO3, PRKN, UBE2H, TRAF3, CUL1, OBI1, TRIM68, RNF217, RNF167, ANKIB1, UBA7, WDSUB1, BIRC7, RMND5A, FBXO4, STUB1, ERCC8, RFWD3, UBE2E3, FANCL, FBXO10, RNF6, UBE2D4, TRIM32, UBR4, RNF43, RNF135, LNX1, MGRN1, NEDD4, UBR1, RC3H2, PEX12, RFPL1, CUL5, FBXO24, BIRC2, RNF213, UBR3, UHRF2, RLIM, FBXL3, UBE2L3, FBXO25, MYLIP, RSPRY1, SHARPIN, UBE2T, ANAPC11, RNF103, CUL2, RNF187, RC3H1, TRAF7, RNF214, FBXO22, UBE2E2, NEDD4L, FBXW2, WWP2, RNF13, CBL, RNF19B, HACE1, RNF139, RCHY1, RBCK1, WWP1, KLHL21, KLH |
| ubiquitin-protein transferase inhibitor activity | molecular function | CDKN2A |
| ubiquitin-protein transferase regulator activity | molecular function | TRIB3, TRIB1, TRIB2 |
| ubiquitin-specific protease binding | molecular function | BAG6, RAD23A, PARK7, SELENOS, DERL2, DERL1, PRKN, SART3, PDZD3, RHBDD2, CLTC, SYVN1, MARCHF6, DERL3, AMFR, CHMP3 |
| ubiquitin-ubiquitin ligase activity | molecular function | UBR5, UBE4A, PRPF19, PELI1, STUB1, PELI2, ANAPC11, UBE2K, UBE4B, RBX1, PPIL2, UBOX5, AMFR |
| ubiquitinyl hydrolase activity | molecular function | USP47, EIF3F, DESI2, USP12, YOD1, USP7, USP9X, OTUD5 |
| UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity | molecular function | GYG1, GYG2 |
| UDP-galactose transmembrane transporter activity | molecular function | SLC35A1, SLC35B1, SLC35A3, SLC35A2 |
| UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity | molecular function | B3GALNT1, B3GAT1, B3GALT2, B3GALT6, B3GALT1, B3GALT5 |
| UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity | molecular function | B4GALT6, B4GALT5, UGT8 |
| UDP-galactosyltransferase activity | molecular function | B3GALT6, B4GALT1 |
| UDP-glucose 4-epimerase activity | molecular function | GALE |
| UDP-glucose 6-dehydrogenase activity | molecular function | UGDH |
| UDP-glucose transmembrane transporter activity | molecular function | SLC35B1 |
| UDP-glucose:glycoprotein glucosyltransferase activity | molecular function | UGGT1, UGGT2 |
| UDP-glucose:hexose-1-phosphate uridylyltransferase activity | molecular function | GALT |
| UDP-glucosyltransferase activity | molecular function | POGLUT3, POGLUT1 |
| UDP-glucuronate decarboxylase activity | molecular function | UXS1 |
| UDP-glucuronic acid transmembrane transporter activity | molecular function | SLC35D1, SLC35D2 |
| UDP-glycosyltransferase activity | molecular function | UGT2B7, UGT2B10, PIGA, UGT1A8, UGT2B11, UGT1A4, UGT2B28, UGT2B15, UGT2B4, UGT2A3, UGT2B17, UGT3A1, UGT2A1, UGT1A9, UGT1A6, UGT1A3, UGT1A5, UGT1A7, UGT1A10, UGT8 |
| UDP-N-acetylgalactosamine transmembrane transporter activity | molecular function | SLC35D1, SLC35D2 |
| UDP-N-acetylglucosamine 2-epimerase activity | molecular function | GNE |
| UDP-N-acetylglucosamine 4-epimerase activity | molecular function | GALE |
| UDP-N-acetylglucosamine diphosphorylase activity | molecular function | UAP1 |
| UDP-N-acetylglucosamine transmembrane transporter activity | molecular function | SLC35D1, SLC35D2, SLC35A3 |
| UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity | molecular function | DPAGT1 |
| UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity | molecular function | DPAGT1, GNPTG |
| UDP-xylosyltransferase activity | molecular function | LARGE2, LARGE1, GXYLT1, POGLUT3, POGLUT1, XXYLT1 |
| UFM1 activating enzyme activity | molecular function | UBA5 |
| UFM1 conjugating enzyme activity | molecular function | UFC1 |
| UFM1 hydrolase activity | molecular function | UFSP2 |
| UFM1 transferase activity | molecular function | UFC1 |
| UMP kinase activity | molecular function | CMPK1 |
| unfolded protein binding | molecular function | HSP90AA1, HSPA9, HSPA2, HSPA5, HSPA1A, HSPA1B, HSPD1, HSPA1L, HSPA8, CCT5, CCT4, GRPEL1, NPM1, PPIB, CANX, SCAP, PTGES3, SHQ1, DNAJA4, CCT7, AHSP, DNAJB11, CLPX, HSPA14, SRSF12, CCT6B, PFDN5, TTC1, NACA2, NDUFAF1, DNAJA2, ST13, CCT2, DNAJB4, AIP, CRYAB, HSP90B1, TCP1, CCT6A, NAP1L4, RUVBL2, HTRA2, MKKS, LMAN1, CCT3, DNAJB8, PFDN4, PDRG1, SCG5, NUDCD2, CDC37L1, PET100, CCT8, TUBB4B, TOMM20, DNAJC4, MDN1, AFG3L2, TAPBP, ERN1, HEATR3, CCDC115, PFDN1, HSPA13, TMEM67, ERLEC1, SIL1, DNAJB1, ERO1B, PFDN6, TRAP1, SYVN1, UGGT1, AIPL1, HSPA6, NUDC, CRYAA, APCS, NUDCD3, SPG7, DNAJB2, HSPE1, CHAF1A, ERN2, GRPEL2, NACAD, CALR, RP2, SERPINH1, PPIA, CDC37, UGGT2 |
| unmethylated CpG binding | molecular function | DNMT1, DNMT3B, CXXC1, KMT2A, KDM2A, TLR9, FBXL19, KMT2B |
| uracil binding | molecular function | DPYS, DPYD |
| uracil DNA N-glycosylase activity | molecular function | APEX1, TDG, SMUG1, UNG |
| urate transmembrane transporter activity | molecular function | SLC17A3, SLC22A12, ABCG2 |
| urea channel activity | molecular function | SLC14A1, AQP9 |
| urea transmembrane transporter activity | molecular function | AQP7, SLC14A1, AQP9, AQP3, AQP10, SLC14A2 |
| uridine kinase activity | molecular function | UCK1, UCKL1, CMPK1, UCK2 |
| uridine phosphorylase activity | molecular function | UPP1, UPP2 |
| uridine transmembrane transporter activity | molecular function | SLC28A2, SLC28A1, SLC29A2, SLC29A1, SLC28A3 |
| uridine-diphosphatase activity | molecular function | ENTPD5, CANT1, ENTPD4 |
| uridylate kinase activity | molecular function | CMPK1, DTYMK |
| uridylyltransferase activity | molecular function | UAP1, UGP2, TUT7 |
| URM1 activating enzyme activity | molecular function | MOCS3 |
| urocanate hydratase activity | molecular function | UROC1 |
| urokinase plasminogen activator receptor activity | molecular function | PLAUR |
| uroporphyrinogen decarboxylase activity | molecular function | UROD |
| uroporphyrinogen-III synthase activity | molecular function | UROS |
| urotensin II receptor activity | molecular function | UTS2R, GPR84 |
| UTP binding | molecular function | HSP90AA1, MTPAP |
| UTP:glucose-1-phosphate uridylyltransferase activity | molecular function | UGP2 |
| V1A vasopressin receptor binding | molecular function | AVP |
| V1B vasopressin receptor binding | molecular function | AVP |
| valine-tRNA ligase activity | molecular function | VARS1, VARS2 |
| vascular endothelial growth factor binding | molecular function | KDR, PTN, FLT4, PDGFRB, PDGFRA, NRP1 |
| vascular endothelial growth factor receptor 1 binding | molecular function | VEGFA, VEGFB |
| vascular endothelial growth factor receptor 2 binding | molecular function | VEGFA, ITGA5, DAB2IP, CCDC88A, ITGB3, CDH5, GREM1 |
| vascular endothelial growth factor receptor 3 binding | molecular function | VEGFC |
| vascular endothelial growth factor receptor binding | molecular function | VEGFA, VEGFC, CD2AP, VEGFB |
| vascular endothelial growth factor-activated receptor activity | molecular function | FLT1, KDR, FLT4, NRP2, PDGFRA, NRP1 |
| vasoactive intestinal polypeptide receptor activity | molecular function | ADCYAP1R1, VIPR2 |
| vasopressin receptor activity | molecular function | OXTR, INPP5K, AVPR2, AVPR1B |
| VEGF-A-activated receptor activity | molecular function | FLT1 |
| VEGF-B-activated receptor activity | molecular function | FLT1 |
| VEGF-C-activated receptor activity | molecular function | FLT4 |
| very long chain acyl-CoA hydrolase activity | molecular function | BAAT |
| very long-chain fatty acid-CoA ligase activity | molecular function | SLC27A3, SLC27A5, SLC27A1, ACSL4, SLC27A2, SLC27A4, ACSF3, ACSBG1 |
| very-long-chain 3-hydroxyacyl-CoA dehydratase activity | molecular function | HACD1, HACD2, HACD3 |
| very-long-chain 3-ketoacyl-CoA synthase activity | molecular function | ELOVL6, ELOVL4, ELOVL2, ELOVL5, ELOVL1, ELOVL3 |
| very-long-chain enoyl-CoA reductase activity | molecular function | TECR |
| very-long-chain-(S)-2-hydroxy-acid oxidase activity | molecular function | HAO2, HAO1 |
| very-long-chain-acyl-CoA dehydrogenase activity | molecular function | ACAD11, ACAD9, ACADVL |
| very-low-density lipoprotein particle binding | molecular function | VLDLR, TREM2, PCSK9 |
| very-low-density lipoprotein particle receptor activity | molecular function | LDLR, VLDLR, APOBR |
| very-low-density lipoprotein particle receptor binding | molecular function | APOE, LRPAP1, PCSK9, RELN |
| vinculin binding | molecular function | SYNM, DMD, PXN, CTNNA1, RTCB, UTRN, SORBS3, ACTN1, DAG1, CORO2B, TLN1 |
| virion binding | molecular function | CRP, TSG101, ANXA9, CD209, HIPK2, NECTIN1, APCS, SIGLEC1, PPIA |
| virus receptor activity | molecular function | ICAM1, AXL, ITGB1, ITGA5, ITGAV, CD46, HSPA1A, HSPA1B, NCAM1, CCR5, ACE2, CLDN6, CXCR4, CD55, SLC1A5, CLDN9, ITGB5, CD81, SCARB2, TFRC, LDLR, IDE, SCARB1, MRC1, CD86, MOG, CD209, ITGA2, ITGB6, TNFRSF4, ITGB3, HYAL3, NECTIN4, GYPA, DPP4, SERPINB3, CXADR, F11R, NPC1, CR2, RPSA, LAMP1, ITGB7, HYAL2, SELPLG, CLEC4G, TNFRSF14, NECTIN1, CD4, EPHA2, EFNB2, SIVA1, DAG1, EFNB3, CLEC5A, XPR1, CLDN1, PVR, SLAMF1, SLC52A2, SLC20A2, ANPEP, SLC52A1, CDHR3, CD80, TYRO3 |
| vitamin binding | molecular function | TTPA, PYGL |
| vitamin D 24-hydroxylase activity | molecular function | CYP1A1 |
| vitamin D binding | molecular function | GC, CALB1, IRX5, KL, S100G |
| vitamin D receptor binding | molecular function | MED4, TAF7, TAF11, MED14, MED13, SNW1, MED30, MED16, MED12, THRAP3, MED24, TOB2 |
| vitamin D response element binding | molecular function | VDR |
| vitamin D3 25-hydroxylase activity | molecular function | CYP2R1 |
| vitamin E binding | molecular function | AFM, SEC14L2, TTPA |
| vitamin transmembrane transporter activity | molecular function | SLC19A3, C2orf83, SLC19A2 |
| vitamin transporter activity | molecular function | GC |
| vitamin-K-epoxide reductase (warfarin-insensitive) activity | molecular function | VKORC1 |
| vitamin-K-epoxide reductase (warfarin-sensitive) activity | molecular function | VKORC1L1, VKORC1 |
| voltage-gated anion channel activity | molecular function | VDAC2, VDAC1, SLC17A3, GPR89A, GPR89B |
| voltage-gated calcium channel activity | molecular function | CATSPER1, CATSPER2, GAS6, IL1RAPL1, ITGAV, CACNA2D1, CATSPER4, CATSPER3, CACNA1S, CACNA1E, CACNG2, RYR1, CACNG6, CACNA1C, CACNG3, CACNG7, PKD2, CACNA2D2, CACNA1A, CACHD1, NCS1, CACNA1G, CACNA1I, TPCN2, CACNG4, CACNB4, CALHM1, CACNA1H, CACNA1D, CACNB1, CACNG1, TMC1, CACNB3, CACNA1B, CACNA2D4, CACNA2D3, TPCN1, CACNB2, TMC2, CACNG8 |
| voltage-gated calcium channel activity involved in AV node cell action potential | molecular function | CACNA1C, CACNA1G, CACNB2 |
| voltage-gated calcium channel activity involved in cardiac muscle cell action potential | molecular function | CACNA2D1, CACNA1C, CACNA1D, CACNB2 |
| voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels | molecular function | CNR1, CDK5, CACNA1D, CACNB2 |
| voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels | molecular function | NCS1, HTR1B |
| voltage-gated calcium channel activity involved SA node cell action potential | molecular function | CACNA1G, CACNA1D |
| voltage-gated cation channel activity | molecular function | CACNA1E, HVCN1, PKD2, HCN1 |
| voltage-gated chloride channel activity | molecular function | CLCN2, CLCN1, CLCNKA, ANO6, CLCN7, CLCNKB, CLCN3, CLCN4, CLCN6, ANO1, CLCN5 |
| voltage-gated ion channel activity | molecular function | CATSPER1, CATSPER2, CACNA2D1, KCNK17, KCNK4, CLCN2, CATSPER4, CATSPER3, CACNA1S, KCNJ10, KCNAB1, KCNH6, SCN11A, NOX1, KCNJ16, CYBB, CLCN1, CACNA1E, KCNH3, KCNH4, CACNG2, KCNA4, CLCNKA, KCNH2, ANO6, KCND3, CACNG6, CACNA1C, HVCN1, KCND2, CLIC4, CACNG3, CACNG7, KCNIP4, TMEM37, PKD2, KCND1, KCNQ3, SCN1B, CACNA2D2, KCNG1, CACNA1A, KCNQ2, CLIC3, KCNK10, KCNG4, CLCNKB, KCNC4, KCNB1, SCN2A, KCNJ15, GPR89A, GPR89B, CACNA1G, KCNE4, CLIC5, SCN1A, CACNA1I, CLIC1, KCNJ4, KCNV1, TPCN2, KCNF1, CACNG4, HCN2, CACNB4, KCNA6, KCNJ2, KCNV2, KCNS3, KCNIP1, KCNG2, HCN1, CALHM1, CLIC6, KCNK15, KCNAB3, CACNA1H, KCNE1, KCNA2, KCNJ9, KCNIP2, KCNC1, KCNQ4, CACNA1D, CACNB1, CACNG1, KCNJ8, KCNC2, SCN4A, CACNB3, KCNAB2, SCN4B, KCNK7, HCN4, KCNA3, KCNA1, KCNJ12, TRPM5, KCNIP3, CACNA1B, SCN5A, CACNA2D4, KCNH8, TMEM109, KCNJ1, KCNMA1, KCNC3, NALCN, CACNA2D3, KCNH5, KCNG3, TPCN1, SCN10A, SCN2B, CACNB2, CACNG8, KCNK13, KCNQ5, SCN3B, SCN8A, KCNK6, KCNE3, KCNH7 |
| voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential | molecular function | KCND2, KCNA1 |
| voltage-gated ion channel activity involved in regulation of presynaptic membrane potential | molecular function | KCNC1, KCNC2, KCNA1 |
| voltage-gated potassium channel activity | molecular function | KCNK9, KCNAB1, KCNH6, KCNK2, LRRC26, KCNH3, KCNH4, KCNA4, KCNH2, KCND3, KCND2, PKD2, KCND1, KCNQ3, KCNG1, KCNQ2, KCNG4, SNAP25, KCNC4, LRRC52, KCNB1, KCNE4, KCNV1, KCNF1, HCN2, KCNA6, KCNV2, KCNS3, KCNG2, KCNK1, HCN1, KCNAB3, KCNE1, KCNA2, KCNC1, KCNQ4, KCNC2, KCNAB2, HCN4, KCNA3, KCNA1, KCNH8, KCNMA1, KCNC3, KCNH5, KCNG3, LRRC55, KCNQ5, KCNE3, KCNH7 |
| voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization | molecular function | KCNH2, KCND3, KCNJ2, KCNE1, KCNIP2 |
| voltage-gated potassium channel activity involved in SA node cell action potential depolarization | molecular function | HCN4 |
| voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization | molecular function | KCNH2, KCND3, KCNE4, KCNE1, KCNJ8, KCNE3 |
| voltage-gated proton channel activity | molecular function | HVCN1 |
| voltage-gated sodium channel activity | molecular function | CATSPER4, SCN11A, PKD2, SCN1B, SCN2A, CACNA1G, SCN1A, CACNA1I, HCN2, HCN1, CACNA1H, SCN4A, SCN4B, HCN4, SCN5A, TPCN1, SCN10A, SCN2B, SCN8A |
| voltage-gated sodium channel activity involved in AV node cell action potential | molecular function | SCN5A |
| voltage-gated sodium channel activity involved in bundle of His cell action potential | molecular function | SCN5A |
| voltage-gated sodium channel activity involved in cardiac muscle cell action potential | molecular function | SCN1B, SCN4B, SCN5A, SCN2B, SCN3B |
| voltage-gated sodium channel activity involved in Purkinje myocyte action potential | molecular function | SCN1B, SCN5A |
| voltage-gated sodium channel activity involved in SA node cell action potential | molecular function | SCN5A |
| volume-sensitive anion channel activity | molecular function | PHLPP2, LRRC28, LRRC8D, LRRC8C, LRRC8B, PHLPP1 |
| volume-sensitive chloride channel activity | molecular function | TTYH2, CLCN3, TTYH1, TTYH3 |
| water channel activity | molecular function | AQP5, AQP7, AQP2, AQP11, AQP9, AQP3, AQP1, AQP6, PDPN, AQP10 |
| water transmembrane transporter activity | molecular function | AQP2, SLC14A1, AQP9, AQP1, PDPN, SLC5A1 |
| WD40-repeat domain binding | molecular function | USP47, CCT6A, DDB1, CDC5L |
| wide pore channel activity | molecular function | PRF1, PANX3, PANX1, PANX2 |
| Wnt-activated receptor activity | molecular function | EGF, RYK, ROR1, FZD9, FZD8, FZD4, FZD2, FZD3, FZD7, LRP6, TSPAN12, LRP5, FZD5, FZD6, LRP5L, FZD1 |
| Wnt-protein binding | molecular function | EGF, RYK, ROR1, FZD9, FZD8, FZD4, WLS, FZD2, FRZB, FZD3, FZD7, LRP6, WIF1, TRABD2B, LRP5, PTPRO, SFRP2, FZD5, SFRP5, FZD6, SFRP4, APCDD1, TRABD2A, CTHRC1, ROR2, LRP5L, FZD1, APCDD1L, RECK |
| WW domain binding | molecular function | CDC25C, TP63, TCEAL8, TCEAL4, WBP11, RAPGEF2, PMEPA1, SCNN1G, DAZAP2, KIF20B, TCEAL2, TCEAL9, LITAF, NDFIP1, NDFIP2, ENAH, SCNN1A, TCEAL1, TRAF4, NFE2, TCEAL3, FAM189B, TCEAL7, TREX1, TCEAL5, SHISA5, SCNN1B |
| X11-like protein binding | molecular function | CLSTN1 |
| xanthine dehydrogenase activity | molecular function | XDH, AOX1 |
| xanthine oxidase activity | molecular function | XDH |
| xenobiotic transmembrane transporter activity | molecular function | SLC22A2, SLC17A3, RALBP1, SLC47A1, ABCC3, EBP, SLC47A2, SLC22A4, ABCC5, ABCC4, SLC22A1, SLC22A3, ABCG2 |
| xenobiotic-transporting ATPase activity | molecular function | ABCB1, ABCG2 |
| XTP binding | molecular function | NUDT16 |
| xylosyltransferase activity | molecular function | LARGE2, LARGE1 |
| xylulokinase activity | molecular function | XYLB |
| Y-form DNA binding | molecular function | MSH2, RBBP8, MEN1, BLM, RAD18 |
| zinc ion binding | molecular function | NR5A2, SOD1, ESR1, TP53, PGR, MMP2, AR, VDR, ACE, MMP9, RAG1, WT1, BRCA1, NR5A1, ESR2, BIRC5, NR1I2, DNMT1, S100A12, MDM2, UBR2, MTR, RNF17, MBD1, MTA2, ALB, NR3C1, PARP1, TNP2, ADAMTS1, ADAMTS5, ZFP37, KAT7, ACR, MMP12, NANOS2, LIN28B, ZDBF2, PDXK, MEFV, MMP7, THRB, NR2F2, PPARG, GATA4, ADAMTS20, SHH, NANOS1, ZNF331, RNF114, PEX10, RNF8, KDM5C, NR1H3, MYRIP, DPF3, PYGO2, KDM5D, RASSF1, MAN2B1, CA2, S100A9, CPN1, LIMK2, NANOS3, ACE2, CECR1, ALPP, GALT, LTA4H, PAM, MATR3, HDAC4, SUPT4H1, NBR1, NR1D2, ZMYM1, AGBL2, AGBL4, NFXL1, MARCHF3, SIAH1, UBR7, MORC4, ZCCHC13, ZFPM2, ERAP1, POLR1H, ZMYM2, KDM5B, CHORDC1, TRIM17, TRIM24, KLF4, LANCL1, PIAS1, UBR5, ADH4, ADH5, CPM, SHMT1, GLO1, ZNF638, SEC23B, LACTB2, ZNF385B, ERAP2, TRIM74, FBXO11, MIB1, SLC30A5, ZCCHC14, DPF1, USP13, NEIL1, NSMCE2, MTA3, RNF26, IFIH1, TRIM4, SIRT5, DBF4, ZBBX, AIRE, TRIM13, ALPI, ESRRG, PHC1, MBTD1, RGN, BRAP, MSRB3, AOPEP, GATAD1, NSD1, ZNF385A, GATA5, ZSWIM4, TRIM39, CXXC1, USP16, USP3, SIAH2, ZFAND5, LTN1, CPSF4, EPRS1, RARB, DMD, SORD |
| zinc ion transmembrane transporter activity | molecular function | SLC30A5, SLC30A2, SLC39A12, SLC30A10, SLC39A10, SLC39A5, SLC30A8, SLC39A11, SLC39A8, SLC30A1, SLC39A6, SLC39A13, SLC39A3, SLC30A3, SLC30A6, SLC39A4, SLC39A1, SLC39A14, SLC30A4, SLC39A7 |
| zinc:bicarbonate symporter activity | molecular function | SLC39A8 |
| zymogen binding | molecular function | DMBT1 |
| [acetyl-CoA carboxylase] kinase activity | molecular function | PRKAA2 |
| [acyl-carrier-protein] S-acetyltransferase activity | molecular function | FASN |
| [acyl-carrier-protein] S-malonyltransferase activity | molecular function | MCAT, FASN |
| [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity | molecular function | HS3ST3A1, HS3ST2, HS3ST3B1, HS3ST1, HS3ST4, HS3ST6 |
| [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity | molecular function | HS3ST2 |
| [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity | molecular function | HS3ST3A1, HS3ST3B1 |
| [heparan sulfate]-glucosamine N-sulfotransferase activity | molecular function | NDST4, NDST1, NDST3, NDST2 |
| [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity | molecular function | PRKAA2 |
| [methionine synthase] reductase activity | molecular function | MTRR |
| [myelin basic protein]-arginine N-methyltransferase activity | molecular function | PRMT7 |
| [phosphorylase] phosphatase activity | molecular function | PPP1R3B |
| [pyruvate dehydrogenase (lipoamide)] phosphatase activity | molecular function | PPM1J, PDP1, PDP2, PPM1H |
| amino acid import | NOT|biological process | SH3BP4 |
| amino-acid betaine metabolic process | NOT|biological process | BHMT2 |
| ARF protein signal transduction | NOT|biological process | MYO9B |
| caveola assembly | NOT|biological process | EMP2, CAV3, PACSIN2, CAV2, CAV1 |
| cell proliferation involved in endocardial cushion morphogenesis | NOT|biological process | TGFBR2 |
| centriole replication | NOT|biological process | OFD1, CETN2, CCP110, DEUP1, CETN1, CDK5RAP2, KIAA0753, RTTN, WDR62, CEP63, SASS6, CNTROB, CEP72 |
| ceramide translocation | NOT|biological process | ABCB4, ABCA2 |
| chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration | NOT|biological process | SLIT1, SLIT3, SLIT2 |
| dTTP catabolic process | NOT|biological process | DCTPP1 |
| early endosome to Golgi transport | NOT|biological process | SURF4, SNX2, STX10, STX5, RAB6A, LMAN1, SNX8, TRAPPC10, TMED9, EHD3 |
| establishment of endothelial intestinal barrier | NOT|biological process | RAP2B, TJP1, RAB1A, RAPGEF2, RAPGEF6, FASN, F11R, PTPRS, CLDN1, RAB1B, AFDN |
| induction of bacterial agglutination | NOT|biological process | RNASE2, DMBT1, FGB, RNASE3, SFTPD, FGA, SPON2 |
| inorganic diphosphate transport | NOT|biological process | ENPP3, ANKH, ENPP1 |
| mature conventional dendritic cell differentiation | NOT|biological process | LGALS9, CCL19, CCR7, PRTN3 |
| mRNA cleavage involved in gene silencing by miRNA | NOT|biological process | AGO4, AGO3, AGO2, MOV10, AGO1 |
| mRNA cleavage involved in gene silencing by siRNA | NOT|biological process | AGO4, AGO3, AGO2, AGO1 |
| negative regulation of low-density lipoprotein receptor activity | NOT|biological process | PSEN1, PCSK9, ABCA2 |
| negative regulation of nerve growth factor production | NOT|biological process | FURIN |
| negative regulation of nuclear receptor transcription coactivator activity | NOT|biological process | CREB3 |
| nuclear matrix organization | NOT|biological process | TPR |
| peptidyl-lysine trimethylation | NOT|biological process | SETD3, ATPSCKMT, EEF2KMT, ANTKMT, VCPKMT, ETFBKMT, FAM86C1 |
| photoreactive repair | NOT|biological process | CRY2 |
| poly-N-acetyllactosamine biosynthetic process | NOT|biological process | B4GAT1, B3GNT5, B4GALT5, B3GNT3, B3GNT8, B3GNT4, B3GNT6, B3GNT9, B3GNT7 |
| polyamine deacetylation | NOT|biological process | HDAC6, HDAC10 |
| proepicardium development | NOT|biological process | TGFBR1, ZFP36L1, NKX2-5 |
| protein exit from endoplasmic reticulum | NOT|biological process | SURF4, SEC16A, SEC13, RANGRF, TECPR2, LMAN1, TMED9, PREB, MAP1LC3C |
| protein polyglycylation | NOT|biological process | TTLL10, TTLL3 |
| pyrimidine nucleobase catabolic process | NOT|biological process | DPYSL2, DPYSL3, DPYS, DPYSL5, DPYD, DPYSL4, CRMP1 |
| regulation of activated CD4-positive, alpha-beta T cell apoptotic process | NOT|biological process | CD274 |
| regulation of activated T cell proliferation | NOT|biological process | IDO1, CD274, RIPK3 |
| regulation of amyloid-beta formation | NOT|biological process | PICALM, ROCK1, TMED10 |
| regulation of cardiac muscle cell apoptotic process | NOT|biological process | BMPR1A, ENG |
| regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis | NOT|biological process | ENG |
| regulation of cell proliferation involved in heart morphogenesis | NOT|biological process | ENG |
| regulation of exosomal secretion | NOT|biological process | CHMP6, CHMP3 |
| regulation of glomerular mesangial cell proliferation | NOT|biological process | PDGFA |
| regulation of glucose mediated signaling pathway | NOT|biological process | UBTF |
| regulation of histamine secretion by mast cell | NOT|biological process | SNX6, VAMP3 |
| regulation of histone H4-K20 methylation | NOT|biological process | TTLL12 |
| regulation of homophilic cell adhesion | NOT|biological process | PTPRR, PTPRG, CEACAM1, TENM3 |
| regulation of interleukin-5 production | NOT|biological process | LGALS9, IL5RA |
| regulation of locomotion involved in locomotory behavior | NOT|biological process | GNB3, DRD3, DRD2 |
| regulation of male germ cell proliferation | NOT|biological process | RHBDD1 |
| regulation of mRNA polyadenylation | NOT|biological process | NCBP2, NCBP1, ZC3H3, SNRPA |
| regulation of neural crest cell differentiation | NOT|biological process | BMPR1A |
| regulation of neutrophil extravasation | NOT|biological process | OLFM4, FUT7 |
| regulation of phospholipase C activity | NOT|biological process | RASGRP1 |
| regulation of post-translational protein modification | NOT|biological process | PPIB, ABCA2 |
| regulation of protein kinase C activity | NOT|biological process | IAPP |
| regulation of T cell apoptotic process | NOT|biological process | CD274, JAK3 |
| regulation of toll-like receptor 4 signaling pathway | NOT|biological process | FLOT1, APPL2, APPL1 |
| regulation of viral release from host cell | NOT|biological process | TSG101, TRIM25, TRIM62, TRIM31 |
| response to bile acid | NOT|biological process | FGFR4 |
| RIG-I signaling pathway | NOT|biological process | TRIM25, LSM14A, RNF135, PHB2, CLPB |
| spermidine deacetylation | NOT|biological process | HDAC6, HDAC10 |
| superior endocardial cushion morphogenesis | NOT|biological process | TGFBR2 |
| tight junction assembly | NOT|biological process | CLDN12, CLDN5, ACTG1 |
| super elongation complex | NOT|cellular component | AFF2, AFF3, AFF1, EAF2, EAF1 |
| U4atac/U6atac snRNP | NOT|colocalizes with | SART3 |
| 1-aminocyclopropane-1-carboxylate synthase activity | NOT|molecular function | ACCS |
| acetyl-CoA binding | NOT|molecular function | TAF1, NAA80, PANK1 |
| acetylspermidine deacetylase activity | NOT|molecular function | HDAC6, HDAC10 |
| adenosylhomocysteinase activity | NOT|molecular function | AHCYL1, AHCY, AHCYL2 |
| AP-2 adaptor complex binding | NOT|molecular function | RAB38, FCHO1, RAB32, BMP2K, OTOF, AAK1, SIDT2, TBC1D5 |
| betaine-homocysteine S-methyltransferase activity | NOT|molecular function | BHMT2 |
| C-8 sterol isomerase activity | NOT|molecular function | SREBF2, EBP |
| C-rich strand telomeric DNA binding | NOT|molecular function | NABP2 |
| ceramide floppase activity | NOT|molecular function | ABCB4, ABCA2 |
| cGMP binding | NOT|molecular function | RAPGEF2, CNGA2, PRKG1, PDE11A, CNGB3, PDE5A, PDE6G, PDE10A, PDE2A, CNGB1 |
| chitinase activity | NOT|molecular function | CHI3L1, CTBS, CHI3L2, OVGP1 |
| cyclosporin A binding | NOT|molecular function | CWC27, PPIL6, PPIB, NKTR, PPID, PPIF, PPP3CA, PPIG, RANBP2, PPWD1, PPIH, PPIE, PPP3R1, PPIL2, PPIA, PPIC |
| deoxyribodipyrimidine photo-lyase activity | NOT|molecular function | CRY1, CRY2 |
| dihydropyrimidinase activity | NOT|molecular function | DPYSL2, DPYSL3, DPYS, DPYSL5, DPYSL4, CRMP1 |
| DNA (6-4) photolyase activity | NOT|molecular function | CRY1, CRY2 |
| gap junction hemi-channel activity | NOT|molecular function | PANX3, PANX1, GJA3, GJA5, PANX2 |
| glucose 6-phosphate:inorganic phosphate antiporter activity | NOT|molecular function | SLC37A3, SLC37A4, SLC37A1, SLC37A2 |
| glycerol-3-phosphate dehydrogenase [NAD+] activity | NOT|molecular function | GPD1L |
| N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity | NOT|molecular function | B4GAT1, B3GNT5, B3GNT3, B3GNT8, B3GNT4, B3GNT6, B3GNT9, B3GNT7 |
| nucleoside triphosphate adenylate kinase activity | NOT|molecular function | AK4, AK3 |
| oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor | NOT|molecular function | LACC1 |
| para-aminobenzoyl-glutamate hydrolase activity | NOT|molecular function | PM20D2 |
| phospholipase D inhibitor activity | NOT|molecular function | SNCA |
| procollagen glucosyltransferase activity | NOT|molecular function | PLOD2, PLOD3 |
| proline racemase activity | NOT|molecular function | L3HYPDH |
| protein-glycine ligase activity | NOT|molecular function | TTLL10, TTLL3 |
| steroid receptor RNA activator RNA binding | NOT|molecular function | SRA1 |
| telomeric G-quadruplex DNA binding | NOT|molecular function | POT1, BLM |
| threonine synthase activity | NOT|molecular function | THNSL2 |
| type 8 metabotropic glutamate receptor binding | NOT|molecular function | PRNP |
| ubiquitin-like protein transferase activity | NOT|molecular function | AKTIP, RNF14, ARIH1, RNF139, ATG3, UBE2L6, UBL4A, ATG16L1 |
| voltage-gated channel activity | NOT|molecular function | TMEM266 |
| GO NAME | QUALIFIER | SYMBOL |