• PMID: 3610359
• Gene Name: CALM1
• Condition: Associated with sperm motility, euspermic and infertile asthenozoospermic
• Association: Associated
• Sex: Male
• Infertility type: Male infertility
• Other associated phenotypes: Associated with sperm motility, euspermic and infertile asthenozoospermic

Concentrations of calmodulin in sperm in relation to their motility in fertile euspermic and infertile asthenozoospermic men

Reyes A, Martínez R, Luna M, Chavarría ME.

The relationship between calmodulin and sperm motility was assessed in euspermic and asthenozoospermic men using radioimmunoassay and time-lapse photography, respectively. There was a significant decrease in the % sperm motility, mean sperm velocity, motility index and % of progressively motile sperm in the asthenozoospermic group when compared with euspermic men. The former also exhibited a higher % of sperm with erratic or circular motility. Calmodulin concentration in sperm from the asthenozoospermic men was 4.8 +/- 1.4 micrograms/mg protein compared with 12.6 +/- 2.3 in euspermic men (P less than 0.0005). The differences observed in sperm motility characteristics between the two groups may, thus, be due to the observed differences in the concentration of calmodulin. FAU - Reyes, A AU - Reyes A FAU - Martínez, R AU - Martínez R FAU - Luna, M AU - Luna M