• PMID: 315218
• Gene Name: CPN1
• Condition: Male infertility, Oligozoospermia
• Association: Associated
• Sex: Male
• Infertility type: Male infertility
• Associated genes: Kininase
• Other associated phenotypes: Male infertility, Oligozoospermia

Bradykininase and protease inhibitors in seminal plasma of fertile and infertile men

Gecse A, Ottlecz A, Török L, Telegdy G, Morvay J, Sas M.

The level of protease acrosin in the seminal plasma of oligozoospermic men was significantly higher than that of normozoospermic men. The amount of bradykininase in the seminal plasma was very high in both normozoospermic and oligozoospermic patients. When the acrosin and kininase content was referred to one million spermatozoa, seminal plasma kininase was significantly enhanced in oligozoospermic men, while the acrosin activity was similar in normozoospermic fertile men and infertile men. Human seminal plasma inhibitor I (HUSI I) increased along with sperm count. Human seminal plasma inhibitor II (HUSI II) showed no change. The motility of spermatozoa was depressed in oligozoospermic patients. FAU - Gecse, A AU - Gecse A FAU - Ottlecz, A AU - Ottlecz A FAU - Török, L AU - Török L FAU - Telegdy, G AU - Telegdy G FAU - Morvay, J AU - Morvay J