• PMID: 2508450
• Gene Name: DAO
• Condition: Male infertility, sperm motility
• Association: Associated
• Sex: Male
• Infertility type: Male infertility
• Associated genes: DAO
• Other associated phenotypes: Male infertility, sperm motility

[Studies on diamine oxidase (DAO) activity in seminal plasma]

Uchijima Y, Yoshida K, Kobayashi N, Saitoh H.

Diamine oxidase (DAO: EC 1.4.3.6) activity was measured for seminal plasma of patients complaining of infertility to investigate whether measurement of DAO activity in seminal plasma is a significant laboratory examination or not for evaluation of male infertility. (1) DAO activity showed a slight decrease with increasing sperm density, but there was no significant correlation between DAO activity and sperm density. (2) DAO activity was higher in samples with sperm motility below 20%. There was a significant negative correlation between DAO activity and sperm motility. (3) DAO activity was higher in samples with motile sperm count below 10 x 10/ml. In conclusion, the simple spectrophotometric assays for DAO could form the base of a routine examination of male infertility. FAU - Uchijima, Y AU - Uchijima Y AD - Department of Urology, Saitama Medical Center, Saitama Medical School. FAU - Yoshida, K AU - Yoshida K FAU - Kobayashi, N AU - Kobayashi N