• PMID: 20887985
• Gene Name: ESR1
• Condition: Nonsyndromic cryptorchidism
• Association: ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism.
• Population size: 1113
• Population details: 1113 (569 Spanish (180 nonsyndromic cryptorchism, 389 were controls), (193 cryptorchid patients, 351 controls))
• Sex: Male
• Infertility type: Male infertility
• Other associated phenotypes: Nonsyndromic cryptorchidism

ESR1 promoter polymorphism is not associated with nonsyndromic cryptorchidism

Lo Giacco D, Ars E, Bassas L, Galan JJ, Rajmil O, Ruíz P, Caffaratti J, Guarducci E, Ruiz-Castané E, Krausz C.

The ESR1 promoter microsatellite (TA)n was reported as a potential functional polymorphism. In a case-control study, we were unable to demonstrate any association between (TA)n and nonsyndromic cryptorchidism in Italian and Spanish study populations. CI - Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. FAU - Lo Giacco, Deborah AU - Lo Giacco D AD - Andrology Service, Molecular Biology Laboratory, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona, Spain. FAU - Ars, Elisabet AU - Ars E FAU - Bassas, Lluis AU - Bassas L FAU - Galan, José Jorge AU - Galan JJ FAU - Rajmil, Osvaldo AU - Rajmil O FAU - Ruíz, Patricia AU - Ruíz P FAU - Caffaratti, Jorge AU - Caffaratti J FAU - Guarducci, Elena AU - Guarducci E FAU - Ruiz-Castané, Eduard AU - Ruiz-Castané E