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PMID 1897760
Gene Name KLK3
Condition Male infertility
Association Associated
Population size 62
Population details 62 (14 normozoospermia, 17 asthenozoospermia, 18 OAT-syndrome, 13 azoospermia)
Sex Male
Infertility type Male infertility
Associated genes G-SM
Other associated phenotypes Male infertility


Correlation between gamma seminoprotein in seminal plasma and ejaculate parameters

Maier U, Simak R.

Gamma seminoprotein (G-SM) levels in seminal plasma were determinated in 62 ejaculates using an enzymimmunoassay. There was no statistical significant difference in G-SM between men with normozoospermia (n = 14), asthenozoospermia (n = 17), OAT-syndrome (n = 18) and azoospermia (n = 13). Also there was no correlation of G-SM levels in those samples with normal (n = 14) or pathological (n = 35) motility and normal (n = 17) or pathological (n = 32) swelling test. Ejaculates with high viscosity (n = 12) showed similar G-SM levels than those with normal (n = 50) viscosity. According to these results seminal G-SM levels does not appear to provide an useful marker for evaluation of male fertility. FAU - Maier, U AU - Maier U AD - Department of Urology, University of Vienna, Medical School, Wien, Austria.