• PMID: 17559848
• Gene Name: INSL3
• Condition: Infertility
• Association: The common INSL3 G178A polymorphism was not statistically significantly associated with male infertility (P>.05), even though INSL3 is essential for the occurrence of bilateral cryptorchidism.
• PMID: 17559848
• Gene Name: INSL3
• Condition: Nonobstructive male infertility, bilateral cryptorchidism
• Association: The common INSL3 G178A polymorphism was not statistically significantly associated with male infertility (P>.05), even though INSL3 is essential for the occurrence of bilateral cryptorchidism.
• Mutation: INSL3 G178A polymorphism
• Sex: Male
• Infertility type: Male infertility
• Other associated phenotypes: Nonobstructive male infertility, bilateral cryptorchidism

Preliminary analysis of the G178A polymorphism of insulin-like factor 3 in male infertility

Yun YJ, Lee HC, Kim JE, Song SH, Lee S.

We investigated the association of nonsynonymous insulin-like factor 3 (INSL3) G178A polymorphism with nonobstructive male infertility. The common INSL3 G178A polymorphism was not statistically significantly associated with male infertility (P>.05), even though INSL3 is essential for the occurrence of bilateral cryptorchidism. FAU - Yun, Yeo-Jin AU - Yun YJ AD - Functional Genomics Lab, CHA Research Institute, Bundang Campus, College of Medicine, Pochon CHA University, Sungnam City, Kyunggi-Do, Korea. FAU - Lee, Han-Chul AU - Lee HC FAU - Kim, Jee-Eun AU - Kim JE FAU - Song, Seung-Hun AU - Song SH