• PMID: 12876366
• Gene Name: PARK7
• Condition: Male infertility, parkinson
• Association: Associated
• Sex: Male
• Infertility type: Male infertility
• Associated genes: DJ-1
• Other associated phenotypes: Male infertility, parkinson

Crystallization and preliminary crystallographic analysis of DJ-1, a protein associated with male fertility and parkinsonism

Honbou K, Suzuki NN, Horiuchi M, Taira T, Niki T, Ariga H, Inagaki F.

DJ-1 was identified as a novel oncogene product that transformed mouse NIH3T3 cells in cooperation with activated Ras. DJ-1 was also correlated with male infertility and parkinsonism. DJ-1 was crystallized using sodium citrate and HEPES at pH 7.5. The crystal belongs to space group P3(1) or P3(2), with unit-cell parameters a = 75.04, c = 74.88 A and contains two molecules in an asymmetric unit. An intensity data set was collected to 2.00 A resolution. FAU - Honbou, Kazuya AU - Honbou K AD - Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. FAU - Suzuki, Nobuo N AU - Suzuki NN FAU - Horiuchi, Masataka AU - Horiuchi M FAU - Taira, Takahiro AU - Taira T FAU - Niki, Takeshi AU - Niki T FAU - Ariga, Hiroyoshi AU - Ariga H