• PMID: 12793288
• Gene Name: FAS
• Condition: Cryptorchidism
• Association: The results seem to dismiss FAS as a modulation apoptosis factor in the cryptorchidism.
• Sex: Male
• Infertility type: Male infertility
• Other associated phenotypes: Cryptorchidism

[Apoptosis in the cryptorchidism. Role of the FAS protein in it's modulation]

Paredes Esteban RM, Ramírez Chamond R, Velasco Sánchez B, Cuevas C, Rodríguez Vargas J, Marín Hidalgo M, García Ruiz M.

The cellular degeneration, present at the criptorchidism leads to a malfunction in the spermatogenosis and it's due to cellular apoptosis (programed cellular death). This process is turned on and modulated by different ways. One of then is mediated by Ag-Ac reactions and a protein called FAS seems to have an important role in it's modulation. We studied the relation between FAS an the increased apoptosis in undescended testics. Testicular biopsies were done in criptorchid patients during orchidopexy and FAS was measured by immune-techniques. Our results seem to dismiss FAS as a modulation apoptosis factor in the cryptorchidism. FAU - Paredes Esteban, R M AU - Paredes Esteban RM AD - Sección de Cirugía Infantil, Hospital Ciudad de Jaén, Jaén. FAU - Ramírez Chamond, R AU - Ramírez Chamond R FAU - Velasco Sánchez, B AU - Velasco Sánchez B FAU - Cuevas, C AU - Cuevas C FAU - Rodríguez Vargas, J AU - Rodríguez Vargas J FAU - Marín Hidalgo, M AU - Marín Hidalgo M