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Gene id 9724
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary
Gene Symbol UTP14C   Gene   UCSC   Ensembl
Aliases 2700066J21Rik, KIAA0266, UTP14B
Gene name UTP14C, small subunit processome component
Alternate names U3 small nucleolar RNA-associated protein 14 homolog C, UTP14, U3 small nucleolar ribonucleoprotein, homolog C, UTP14, small subunit processome component homolog C,
Gene location 13q14.3 (52024690: 52033599)     Exons: 2     NC_000013.11
OMIM 608969

Protein Summary
Protein general information Q5TAP6  

Name: U3 small nucleolar RNA associated protein 14 homolog C

Length: 766  Mass: 87,188

Sequence MNVNQVAENLALSHQEELVDLPKNYPLSENEDEGDSDGERKHQKLLEAIISLDGKNRRKLAERSEASLKVSEFSV
SSEGSGEKLGLADLLEPVKTSSSLATVKKQLNRVKSKKVVELPLNKEKIEQIHREVAFSKTSQVLSKWDPIILKN
QQAEQLVFPLGKEQPAIAPIEHALSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPMEKASLQAMSLEEAKMHRAE
LQRARALQSYYEAKARKEKKIKSKKYHKVVKKGKAKKALKEFEQLQKVNPTVALEEMEKIENARMMERMSLKHQN
SGKWAKSKAIMAKYDLEARQAMQEQLAKNKELTQKLQVASESEEEEGGTEVEELLVPHVANEVQMNVDGPNPWMF
RSCTSDTKEAATQEDPEQVPELAAHEVSASEAEERPVAEEEILLREFEERQSLRKRSELNQDAEPASSQETKDSS
SQEVLSELRALSQKLKEKHQSRKQKASSEGTVPQVQREEPAPEEAEPLLLQRSERVQTLEELEELGKEDCFQNKE
LPRPVLEGQQSERTPNNRPDAPKEKKEKEQLINLQNFLTTQSPSVRSLAVPTIIEELEDEEERDQRQMIKEAFAG
DDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRQFLIKAPEGPPRKDKNLPNVIISEKRNIH
AAAHQVQVLPYPFTHHRQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIIKPIKAEDVGYQSSSRSDLPVIQ
RNPKRITTRHNKEEKL
Structural information
Interpro:  IPR006709  
MINT:  
STRING:   ENSP00000428619
Other Databases GeneCards:  UTP14C  Malacards:  UTP14C

Gene ontology

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GO accessionTerm nameEvidence codeGo category
GO:0005730 nucleolus
 IBA cellular component
GO:0007275 multicellular organism de
velopment
 IEA biological process
GO:0007283 spermatogenesis
 IEA biological process
GO:0030154 cell differentiation
 IEA biological process
GO:0030490 maturation of SSU-rRNA
 IBA biological process
GO:0032040 small-subunit processome
 IBA cellular component
GO:0051321 meiotic cell cycle
 IEA biological process
GO:0005634 nucleus
 IEA cellular component
GO:0005730 nucleolus
 IBA cellular component
GO:0005730 nucleolus
 IEA cellular component
GO:0006364 rRNA processing
 IEA biological process
GO:0007275 multicellular organism de
velopment
 IEA biological process
GO:0007283 spermatogenesis
 IEA biological process
GO:0030154 cell differentiation
 IEA biological process
GO:0030490 maturation of SSU-rRNA
 IBA biological process
GO:0032040 small-subunit processome
 IEA cellular component
GO:0032040 small-subunit processome
 IBA cellular component
GO:0042254 ribosome biogenesis
 IEA biological process
GO:0051321 meiotic cell cycle
 IEA biological process
GO:0005730 nucleolus
 IBA cellular component
GO:0030490 maturation of SSU-rRNA
 IBA biological process
GO:0032040 small-subunit processome
 IBA cellular component

Diseases

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Associated diseases References
Male factor infertility MIK: 16354793
Male fertility MIK: 16354793
Role in spermatid development MIK: 17291484
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
16354793 Male ferti
lity
442 (234 nonobs
tructive, azoos
permic/severely
oligospermic m
ales, 208 prove
n-fertile contr
ols)
 Male infertility UTP14c
 Show abstract
17291484 Role in sp
ermatid de
velopment

Male infertility
Show abstract
17327269 Teratozoos
permia
13 (5 controls,
8 cases)
 Male infertility GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
 Show abstract