• Gene id: 9715

Gene Summary

• Gene Symbol: FAM131B   Gene   UCSC   Ensembl
• Gene name: family with sequence similarity 131 member B
• Alternate names: protein FAM131B,
• Gene location: 7q34 (143382303: 143353399)     Exons: 11     NC_000007.14

Protein Summary

• Protein general information: Q86XD5  
  • Name: Protein FAM131B
  • Length: 332  
  • Mass: 35769
• Sequence:

  MDSTSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLKRNSNAYGIGALAKSSFSGISRSMKDHVTKPT
  AMGQGRVAHMIEWQGWGKTPAVQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGED
  MSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEASDQSLIASPATGSYLGPAF
  DDSQPSLHEMGPSQPASGYSALEPPPLLGGDTDWAPGVGAVDLARGPAEEEKRPLAPEEEEDAGCRDLESLSPRE
  DPEMSTALSRKVSDVTSSGVQSFDEEEGEANN

• Structural information:
  • Interpro: IPR026782  
  • STRING: ENSP00000410603
• Other Databases: GeneCards:  FAM131B  Malacards:  FAM131B

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881