|
Gene id |
9532 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
BAG2 Gene UCSC Ensembl |
|
Aliases |
BAG-2, dJ417I1.2 |
|
Gene name |
BCL2 associated athanogene 2 |
|
Alternate names |
BAG family molecular chaperone regulator 2, bcl-2-associated athanogene 2, dJ417I1.2 (BAG-family molecular chaperone regulator 2), |
|
Gene location |
6p12.1 (57172325: 57189832) Exons: 5 NC_000002.12
|
|
Gene summary(Entrez) |
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicte
|
|
OMIM |
603882 |
|
| Pathway id | Pathway name |
|---|
| hsa04141 | Protein processing in endoplasmic reticulum | |
|
| Associated diseases |
References |
| Spermatogenesis defects | MIK: 24899640 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Essential for spermatogenesis | MIK: 24899640 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 24899640 |
Essential
for sperma
togenesis
|
|
|
|
Male infertility |
HSPBP1
BAG2
HSPA4
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|