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Gene id |
953 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
ENTPD1 Gene UCSC Ensembl |
|
Aliases |
ATPDase, CD39, NTPDase-1, SPG64 |
|
Gene name |
ectonucleoside triphosphate diphosphohydrolase 1 |
|
Alternate names |
ectonucleoside triphosphate diphosphohydrolase 1, CD39 antigen, ecto-ATP diphosphohydrolase 1, ecto-ATPDase 1, ecto-ATPase 1, ecto-apyrase, lymphoid cell activation antigen, |
|
Gene location |
10q24.1 (95710900: 95877265) Exons: 18 NC_000015.10
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|
Gene summary(Entrez) |
The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found f
|
|
OMIM |
601752 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Hereditary spastic paraplegia | KEGG: H00266 |
| Diabetes | GAD: 19095759 |
| Alzheimer's disease | GAD: 16385451 |
| Male factor infertility | MIK: 25160621 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Male infertility | MIK: 25160621 |
| Teratozoospermia | MIK: 17327269 |
|
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25160621 |
Male infer
tility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|