• Gene id: 93953

Gene Summary

• Gene Symbol: GCNA   Gene   UCSC   Ensembl
• Aliases: ACRC, NAAR1
• Gene name: germ cell nuclear acidic peptidase
• Alternate names: acidic repeat-containing protein, acidic repeat containing, germ cell nuclear antigen, putative nuclear protein,
• Gene location: Xq13.1 (63593410: 63660244)     Exons: 13     NC_000001.11
• OMIM: 300369

Protein Summary

• Protein general information: Q96QF7  
  • Name: Acidic repeat containing protein (Germ cell nuclear antigen)
  • Length: 691  
  • Mass: 76112
  • Tissue specificity: Expressed in germ cells of the testis (at protein level) (PubMed
• Sequence:

  MDGCKKELPRLQEPEEDEDCYILNVQSSSDDTSGSSVARRAPKRQASCILNVQSRSGDTSGSSVARRAPKRQASS
  VVVIDSDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAPD
  DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVP
  DDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSD
  DSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDL
  GENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVE
  PLRKRKAKTKNVSVTPGHKKRGPSKKKPGAAKVEKRKTRTPKCKVPGCFLQDLEKSKKYSGKNLKRNKDELVQRI
  YDLFNRSVCDKKLPEKLRIGWNNKMVKTAGLCSTGEMWYPKWRRFAKIQIGLKVCDSADRIRDTLIHEMCHAASW
  LIDGIHDSHGDAWKYYARKSNRIHPELPRVTRCHNYKINYKVHYECTGCKTRIGCYTKSLDTSRFICAKCKGSLV
  MVPLTQKDGTRIVPHV

• Structural information:
  • Protein Domains: (522..67-)
    (/note="SprT-like"-)
  • Interpro: IPR006640  
  • STRING: ENSP00000362799
• Other Databases: GeneCards:  GCNA  Malacards:  GCNA

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IBA	cellular component
GO:0005634	nucleus	IDA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)