• Gene id: 9205

Gene Summary

• Gene Symbol: ZMYM5   Gene   UCSC   Ensembl
• Aliases: HSPC050, MYM, ZNF198L1, ZNF237
• Gene name: zinc finger MYM-type containing 5
• Alternate names: zinc finger MYM-type protein 5, zinc finger protein 198-like 1, zinc finger protein 237, zinc finger, MYM-type 5,
• Gene location: 13q12.11 (19863648: 19823481)     Exons: 9     NC_000013.11
• OMIM: 616443

Protein Summary

• Protein general information: Q9UJ78  
  • Name: Zinc finger MYM type protein 5 (Zinc finger protein 198 like 1) (Zinc finger protein 237)
  • Length: 669  
  • Mass: 74817
• Sequence:

  MEKCSVGGLELTEQTPALLGNMAMATSLMDIGDSFGHPACPLVSRSRNSPVEDDDDDDDVVFIESIQPPSISAPA
  IADQRNFIFASSKNEKPQGNYSVIPPSSRDLASQKGNISETIVIDDEEDIETNGGAEKKSSCFIEWGLPGTKNKT
  NDLDFSTSSLSRSKTKTGVRPFNPGRMNVAGDLFQNGEFATHHSPDSWISQSASFPSNQKQPGVDSLSPVALLRK
  QNFQPTAQQQLTKPAKITCANCKKPLQKGQTAYQRKGSAHLFCSTTCLSSFSHKRTQNTRSIICKKDASTKKANV
  ILPVESSKSFQEFYSTSCLSPCENNWNLKKGVFNKSRCTICSKLAEIRHEVSVNNVTHKLCSNHCFNKYRLANGL
  IMNCCEHCGEYMPSKSTGNNILVIGGQQKRFCCQSCINEYKQMMETKSKKLTASENRKRNAFREENEKQLYGSSN
  TLLKKIEGIPEKKEKTSQLQLSVECGTDTLLIQENVNLPPSSTSTIADTFQEQLEEKNFEDSIVPVVLSADPGTW
  PRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCKLFGEGK
  NQLKNENGCKDWQHLSHILSKHEESEMHVNNSVKYSKLKSDLKKNKAIDAAEHRLYENEKNDGVLLLYT

• Structural information:
  • Interpro: IPR011017  IPR010507  
  • PDB: 2DAS
  • PDBsum: 2DAS
  • STRING: ENSP00000372361
• Other Databases: GeneCards:  ZMYM5  Malacards:  ZMYM5

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0006357	regulation of transcription by RNA polymerase II	IBA	biological process
GO:0022604	regulation of cell morphogenesis	IBA	biological process
GO:0005634	nucleus	IBA	cellular component
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	molecular function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	IDA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0008270	zinc ion binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)