• Gene id: 91752

Gene Summary

• Gene Symbol: ZNF804A   Gene   UCSC   Ensembl
• Aliases: C2orf10
• Gene name: zinc finger protein 804A
• Alternate names: zinc finger protein 804A,
• Gene location: 2q32.1 (184598528: 184939491)     Exons: 4     NC_000002.12
• Gene summary(Entrez): The protein encoded by this gene is a zinc finger binding protein. Polymorphisms in this gene, especially rs1344706, are thought to confer increased susceptibility to schizophrenia, bipolar disorder, and heroin addiciton. [provided by RefSeq, Nov 2015]

Protein Summary

• Protein general information: Q7Z570  
  • Name: Zinc finger protein 804A
  • Length: 1209  
  • Mass: 136888
• Sequence:

  MECYYIVISSTHLSNGHFRNIKGVFRGPLSKNGNKTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNH
  INSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVRENCNE
  ISQRVVVDSVNNQQDFKYTLIHSEENTKDATTVAEDPESANNYTAKNNQVGDQAQGIHRHKIGFSFAFPKKASVK
  LESSAAAFSEYSDDASVGKGFSRKSRFVPSACHLQQSSPTDVLLSSEEKTNSFHPPEAMCRDKETVQTQEIKEVS
  SEKDALLLPSFCKFQLQLSSDADNCQNSVPLADQIPLESVVINEDIPVSGNSFELLGNKSTVLDMSNDCISVQAT
  TEENVKHNEASTTEVENKNGPETLAPSNTEEVNITIHKKTNFCKRQCEPFVPVLNKHRSTVLQWPSEMLVYTTTK
  PSISYSCNPLCFDFKSTKVNNNLDKNKPDLKDLCSQQKQEDICMGPLSDYKDVSTEGLTDYEIGSSKNKCSQVTP
  LLADDILSSSCDSGKNENTGQRYKNISCKIRETEKYNFTKSQIKQDTLDEKYNKIRLKETHEYWFHKSRRKKKRK
  KLCQHHHMEKTKESETRCKMEAENSYTENAGKYLLEPISEKQYLAAEQLLDSHQLLDKRPKSESISLSDNEEMCK
  TWNTEYNTYDTISSKNHCKKNTILLNGQSNATMIHSGKHNLTYSRTYCCWKTKMSSCSQDHRSLVLQNDMKHMSQ
  NQAVKRGYNSVMNESERFYRKRRQHSHSYSSDESLNRQNHLPEEFLRPPSTSVAPCKPKKKRRRKRGRFHPGFET
  LELKENTDYPVKDNSSLNPLDRLISEDKKEKMKPQEVAKIERNSEQTNQLRNKLSFHPNNLLPSETNGETEHLEM
  ETTSGELSDVSNDPTTSVCVASAPTKEAIDNTLLEHKERSENINLNEKQIPFQVPNIERNFRQSQPKSYLCHYEL
  AEALPQGKMNETPTEWLRYNSGILNTQPPLPFKEAHVSGHTFVTAEQILAPLALPEQALLIPLENHDKFKNVPCE
  VYQHILQPNMLANKVKFTFPPAALPPPSTPLQPLPLQQSLCSTSVTTIHHTVLQQHAAAAAAAAAAAAAGTFKVL
  QPHQQFLSQIPALTRTSLPQLSVGPVGPRLCPGNQPTFVAPPQMPIIPASVLHPSHLAFPSLPHALFPSLLSPHP
  TVIPLQPLF

• Structural information:
  • Interpro: IPR022755  IPR036236  IPR013087  
  • Prosite: PS00028
  • STRING: ENSP00000303252
• Other Databases: GeneCards:  ZNF804A  Malacards:  ZNF804A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0098794	postsynapse	IEA	cellular component
GO:0030424	axon	IEA	cellular component
GO:1902952	positive regulation of dendritic spine maintenance	IEA	biological process
GO:0098793	presynapse	IEA	cellular component
GO:0043198	dendritic shaft	IEA	cellular component
GO:0043197	dendritic spine	IEA	cellular component
GO:0043025	neuronal cell body	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0043198	dendritic shaft	IDA	cellular component
GO:0030426	growth cone	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0043197	dendritic spine	IDA	cellular component
GO:1901588	dendritic microtubule	IDA	cellular component
GO:0005886	plasma membrane	IDA	cellular component
GO:0005634	nucleus	IDA	cellular component
GO:0043025	neuronal cell body	IDA	cellular component
GO:0098794	postsynapse	IDA	cellular component
GO:0003674	molecular_function	ND	molecular function
GO:0010975	regulation of neuron projection development	IGI	biological process
GO:0010976	positive regulation of neuron projection development	IMP	biological process
GO:0010628	positive regulation of gene expression	IMP	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq