• Gene id: 91750

Gene Summary

• Gene Symbol: LIN52   Gene   UCSC   Ensembl
• Aliases: C14orf46, c14_5549
• Gene name: lin-52 DREAM MuvB core complex component
• Alternate names: protein lin-52 homolog, lin-52 homolog,
• Gene location: 14q24.3 (74084866: 74201492)     Exons: 10     NC_000014.9
• OMIM: 0

Protein Summary

• Protein general information: Q52LA3  
  • Name: Protein lin 52 homolog
  • Length: 116  
  • Mass: 13001
• Sequence:

  MGWKMASPTDGTDLEASLLSFEKLDRASPDLWPEQLPGVAEFAASFKSPITSSPPKWMAEIERDDIDMLKELGSL
  TTANLMEKVRGLQNLAYQLGLDESREMTRGKFLNILEKPKK

• Structural information:
  • Interpro: IPR018737  
  • PDB: 4YOO 6C48
  • PDBsum: 4YOO 6C48
  • STRING: ENSP00000451812
• Other Databases: GeneCards:  LIN52  Malacards:  LIN52

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0070176	DRM complex	IEA	cellular component
GO:0006351	transcription, DNA-templated	IEA	biological process
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005654	nucleoplasm	TAS	cellular component
GO:0051726	regulation of cell cycle	TAS	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

KEGG pathways

Pathway id	Pathway name
hsa04218	Cellular senescence

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)