• Gene id: 91612

Gene Summary

• Gene Symbol: CHURC1   Gene   UCSC   Ensembl
• Aliases: C14orf52, My015, chch
• Gene name: churchill domain containing 1
• Alternate names: protein Churchill,
• Gene location: 14q23.3 (64914360: 64935367)     Exons: 5     NC_000014.9
• OMIM: 608577

Protein Summary

• Protein general information: Q8WUH1  
  • Name: Protein Churchill
  • Length: 139  
  • Mass: 16111
• Sequence:

  MRQPYLSSREVSSSRKRWRTFPVDCVAMCGDCVEKEYPNRGNTCLENGSFLLNFTGCAVCSKRDFMLITNKSLKE
  EDGEEIVTYDHLCKNCHHVIARHEYTFSIMDEFQEYTMLCLLCGKAEDTISILPDDPRQMTLLF

• Structural information:
  • Interpro: IPR038543  IPR009508  
  • PDB: 2JOX
  • PDBsum: 2JOX
  • STRING: ENSP00000475473
• Other Databases: GeneCards:  CHURC1  Malacards:  CHURC1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008270	zinc ion binding	IEA	molecular function
GO:0045893	positive regulation of transcription, DNA-templated	IEA	biological process
GO:0007275	multicellular organism development	IEA	biological process
GO:0046872	metal ion binding	IEA	molecular function
GO:0007275	multicellular organism development	IEA	biological process
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)