• Gene id: 9085

Gene Summary

• Gene Symbol: CDY1   Gene   UCSC   Ensembl
• Aliases: CDY, CDY1A
• Gene name: chromodomain Y-linked 1
• Alternate names: testis-specific chromodomain protein Y 1, chromodomain protein, Y chromosome, 1, chromodomain protein, Y-linked, 1, testis-specific chromodomain protein on Y,
• Gene location: Yq11.23 (543894: 542623)     Exons: 0     NC_017999.1
• Gene summary(Entrez): This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late
• OMIM: 400016

Protein Summary

Gene ontology

GO accession	Term name	Evidence code	Go category

Diseases

Associated diseases	References
Sertoli cell only syndrome (SCOS)	GAD: 18326516
Cryptorchidism	MIK: 17609244
Azoospermia	MIK: 26149076
Azoospermia	MIK: 18782837
Azoospermia	MIK: 11163833
Male factor infertility	MIK: 24009201
Spermatogenesis defects	MIK: 19088127
Sertoli cell only syndrome (SCOS)	MIK: 11263480
Spermatogenesis defects	MIK: 22927988
Spermatogenesis defects	MIK: 15520406
Hypospermatogenesis	MIK: 11263480
Oligozoospermia	MIK: 26149076
Non obstructive azoospermia	MIK: 25594150
Azoospermia	MIK: 20663794
Azoospermia	MIK: 11163833
Oligozoospermia	MIK: 26149076
Male infertility	MIK: 26149076
Spermatogenic defects	MIK: 14569460
Cryptorchidism	MIK: 17609244
Male infertility	MIK: 25042452
Nonobstructive azoospermia(NOA)	MIK: 25594150
Hypospermatogenesis	MIK: 11263480
Sertoli cell-only syndrome	MIK: 11263480
Spermatogenetic defects	MIK: 19088127
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
26149076	Azoospermia, Oligozoospermia	AZFc subdeletions (gr/gr, b1/b3 and b2/b3)		827 (312 controls, 172 azoospermic and 343 oligozoospermic subjects)	Male infertility	DAZ CDY1
25594150	Nonobstructive azoospermia(NOA), oligozoospermia			354 (120 patients with NOA, 109 with oligozoospermia, and 125 normal male controls)	Male infertility	DAZ CDY
22927988	Impaired spermatogenesis	gr/gr deletion, b2/b3 deleteion, b1/b3 deletion, b3/b4 deletion	Korean	594 (377 patients with azoo-/oligozoospermia, 217 controls)	Male infertility
19088127	Spermatogenetic defects	gr/gr deletion, the b2/b3 deletion	Han Chi nese	1147 (756 idiopathic infertile Han-Chinese, 391 healthy Han-Chinese)	Male infertility
18782837	Azoospermia	gr/gr deletions, b2/b4 duplication		169 men diagnosed with gr/gr deletions	Male infertility
17609244	Cryptorchidism	gr/gr deletion		286 (146 cryptorchid, 140 infertile patients)	Male infertility
15520406	Spermatogenic failure, Male infertility	AZFc deletions (gr/gr and b1/b3)		699 (300 infertile men, 399 control men)	Male infertility
25042452	Male infertility	CDY1a, CDY1b copy deletions	Tunisia n	356 (241 infertile men with different spermatogenic impairments, 115 fertile men)	Male infertility	CDY1a CDY1b
24009201	Male infertility	sY1206 deletion	Chines e (Yi e thnic p opulati on)	377 (224 infertile patients, 153 fertile subjects)	Male infertility	CDY1 DAZ
11263480	Severe hypospermatogenesis, Sertoli cell-only syndrome			17 infertile patients	Male infertility	DAZ  CDY1
11163833	Azoospermia			66 men with azoospermia	Male infertility	DAZ CDY1 RBM
14569460	Complete spermatogenesis				Male infertility
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)