• Gene id: 9043

Gene Summary

• Gene Symbol: SPAG9   Gene   UCSC   Ensembl
• Aliases: CT89, HLC-6, HLC4, HLC6, JIP-4, JIP4, JLP, PHET, PIG6
• Gene name: sperm associated antigen 9
• Alternate names: C-Jun-amino-terminal kinase-interacting protein 4, JNK interacting protein, JNK/SAPK-associated protein, Max-binding protein, c-Jun NH2-terminal kinase-associated leucine zipper protein, cancer/testis antigen 89, human lung cancer oncogene 6 protein, lung cancer,
• Gene location: 17q21.33 (51120867: 50962173)     Exons: 34     NC_000011.10
• Gene summary(Entrez): This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to
• OMIM: 605430

Protein Summary

Gene ontology

GO accession	Term name	Evidence code	Go category

Diseases

Associated diseases	References
Associated with sperm motility	MIK: 25562328
Plays an important role in testis during development	MIK: 18574703
Acrosome reaction	MIK: 25562328
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenetic defects	MIK: 25562328
Testis development	MIK: 18574703
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
18574703	Plays an important role in testis during development				Male infertility
25562328	Associated with sperm motility, acrosome reaction				Male infertility
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881