Gene id |
9027 |
Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
Gene Symbol |
NAT8 Gene UCSC Ensembl |
Aliases |
ATase2, CCNAT, CML1, GLA, Hcml1, TSC501, TSC510 |
Gene name |
N-acetyltransferase 8 (putative) |
Alternate names |
N-acetyltransferase 8, N-acetyltransferase 8 (GCN5-related, putative), N-acetyltransferase 8 (camello like), acetyltransferase 2, camello-like protein 1, cysteinyl-conjugate N-acetyltransferase, kidney- and liver-specific gene product, probable N-acetyltransfera, |
Gene location |
2p13.1 (73642421: 73640722) Exons: 2 NC_000002.12
|
Gene summary(Entrez) |
This gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affect
|
OMIM |
602413 |
Protein Summary
|
Protein general information
| Q9UHE5
Name: N acetyltransferase 8 (EC 2.3.1. ) (Acetyltransferase 2) (ATase2) (Camello like protein 1) (Cysteinyl conjugate N acetyltransferase) (CCNAT) (EC 2.3.1.80)
Length: 227 Mass: 25619
Tissue specificity: Preferentially expressed in liver and kidney. Also detected in brain (at protein level). {ECO
|
Sequence |
MAPCHIRKYQESDRQWVVGLLSRGMAEHAPATFRQLLKLPRTLILLLGGPLALLLVSGSWLLALVFSISLFPALW FLAKKPWTEYVDMTLCTDMSDITKSYLSERGSCFWVAESEEKVVGMVGALPVDDPTLREKRLQLFHLFVDSEHRR QGIAKALVRTVLQFARDQGYSEVILDTGTIQLSAMALYQSMGFKKTGQSFFCVWARLVALHTVHFIYHLPSSKVG SL
|
Structural information |
|
Other Databases |
GeneCards: NAT8 Malacards: NAT8 |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0008080 |
N-acetyltransferase activ ity
|
IBA |
molecular function |
GO:0047198 |
cysteine-S-conjugate N-ac etyltransferase activity
|
IDA |
molecular function |
GO:0005789 |
endoplasmic reticulum mem brane
|
IDA |
cellular component |
GO:0018003 |
peptidyl-lysine N6-acetyl ation
|
IDA |
biological process |
GO:0043066 |
negative regulation of ap optotic process
|
IDA |
biological process |
GO:0018003 |
peptidyl-lysine N6-acetyl ation
|
IDA |
biological process |
GO:0005793 |
endoplasmic reticulum-Gol gi intermediate compartme nt
|
IDA |
cellular component |
GO:0016021 |
integral component of mem brane
|
IDA |
cellular component |
GO:0006749 |
glutathione metabolic pro cess
|
IDA |
biological process |
GO:0033116 |
endoplasmic reticulum-Gol gi intermediate compartme nt membrane
|
IDA |
cellular component |
GO:0004468 |
lysine N-acetyltransferas e activity, acting on ace tyl phosphate as donor
|
IDA |
molecular function |
GO:0004468 |
lysine N-acetyltransferas e activity, acting on ace tyl phosphate as donor
|
IDA |
molecular function |
GO:0050435 |
amyloid-beta metabolic pr ocess
|
IMP |
biological process |
GO:0010628 |
positive regulation of ge ne expression
|
IMP |
biological process |
GO:0010628 |
positive regulation of ge ne expression
|
IMP |
biological process |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0008080 |
N-acetyltransferase activ ity
|
IEA |
molecular function |
GO:0016746 |
transferase activity, tra nsferring acyl groups
|
IEA |
molecular function |
GO:0016740 |
transferase activity
|
IEA |
molecular function |
GO:0005783 |
endoplasmic reticulum
|
IEA |
cellular component |
GO:0016021 |
integral component of mem brane
|
IEA |
cellular component |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0042493 |
response to drug
|
TAS |
biological process |
GO:0047198 |
cysteine-S-conjugate N-ac etyltransferase activity
|
IEA |
molecular function |
GO:0044267 |
cellular protein metaboli c process
|
TAS |
biological process |
GO:0005789 |
endoplasmic reticulum mem brane
|
TAS |
cellular component |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005789 |
endoplasmic reticulum mem brane
|
IEA |
cellular component |
GO:0033116 |
endoplasmic reticulum-Gol gi intermediate compartme nt membrane
|
IEA |
cellular component |
GO:0005783 |
endoplasmic reticulum
|
IDA |
cellular component |
GO:0006749 |
glutathione metabolic pro cess
|
IEA |
biological process |
|
|
|
|
Associated diseases |
References |
Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
21674046 |
Aberrant C pGs in Low Motility Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|