|
Gene id |
8847 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
DLEU2 Gene UCSC Ensembl |
|
Aliases |
ALT1, BCMSUN, DLB2, LEU2, LINC00022, MIR15AHG, NCRNA00022, RFP2, RFP2OS, TRIM13OS |
|
Gene name |
deleted in lymphocytic leukemia 2 |
|
Alternate names |
deleted in lymphocytic leukemia 2 (non-protein coding), leukemia associated gene 2, long intergenic non-protein coding RNA 22, mir-15a-16-1 cluster host gene (non-protein coding), ret finger protein 2 opposite strand, |
|
Gene location |
13q14.2 (50125540: 49982548) Exons: 11 NC_000013.11
|
|
Gene summary(Entrez) |
This locus represents a microRNA host gene and also produces long alternatively spliced non-coding RNAs. This genome region was observed to be deleted or epigenetically suppressed in leukemia, and was implicated as a negative regulator of cell proliferati
|
|
OMIM |
605766 |
|
| Associated diseases |
References |
| Cryptorchidism | MIK: 21412036 |
| Cryptorchidism | MIK: 28606200 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 21412036 |
Cryptorchi
dism
|
|
|
23 (4 controls,
19 cases)
|
Male infertility |
GSE25518 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|