• Gene id: 8800

Gene Summary

• Gene Symbol: PEX11A   Gene   UCSC   Ensembl
• Aliases: PEX11-ALPHA, PMP28, hsPEX11p
• Gene name: peroxisomal biogenesis factor 11 alpha
• Alternate names: peroxisomal membrane protein 11A, 28 kDa peroxisomal integral membrane protein, peroxin-11A, peroxisomal biogenesis factor 11A, protein PEX11 homolog alpha,
• Gene location: 15q26.1 (89690753: 89681534)     Exons: 3     NC_000015.10
• Gene summary(Entrez): This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside sti
• OMIM: 612985

Protein Summary

• Protein general information: O75192  
  • Name: Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin 11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11 alpha)
  • Length: 247  
  • Mass: 28353
• Sequence:

  MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSI
  HATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVT
  CDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLG
  GLVSSIAGMITVAYPQMKLKTR

• Structural information:
  • Interpro: IPR008733  
  • STRING: ENSP00000300056
• Other Databases: GeneCards:  PEX11A  Malacards:  PEX11A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005778	peroxisomal membrane	IBA	cellular component
GO:0016559	peroxisome fission	IBA	biological process
GO:0044375	regulation of peroxisome size	IBA	biological process
GO:0016559	peroxisome fission	IEA	biological process
GO:0005779	integral component of peroxisomal membrane	IEA	cellular component
GO:0007031	peroxisome organization	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0005777	peroxisome	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005778	peroxisomal membrane	TAS	cellular component
GO:0019216	regulation of lipid metabolic process	TAS	biological process
GO:0050873	brown fat cell differentiation	IEA	biological process
GO:0016557	peroxisome membrane biogenesis	IEA	biological process
GO:0005778	peroxisomal membrane	IEA	cellular component
GO:0005778	peroxisomal membrane	IEA	cellular component
GO:0044375	regulation of peroxisome size	IDA	biological process
GO:0032991	protein-containing complex	IDA	cellular component
GO:0042803	protein homodimerization activity	IDA	molecular function
GO:0016559	peroxisome fission	IDA	biological process
GO:0005779	integral component of peroxisomal membrane	IDA	cellular component
GO:0005779	integral component of peroxisomal membrane	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0007165	signal transduction	IMP	biological process
GO:0007031	peroxisome organization	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005778	peroxisomal membrane	IBA	cellular component
GO:0016559	peroxisome fission	IBA	biological process
GO:0044375	regulation of peroxisome size	IBA	biological process
GO:0016559	peroxisome fission	IEA	biological process
GO:0005779	integral component of peroxisomal membrane	IEA	cellular component
GO:0007031	peroxisome organization	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0005777	peroxisome	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005778	peroxisomal membrane	TAS	cellular component
GO:0019216	regulation of lipid metabolic process	TAS	biological process
GO:0050873	brown fat cell differentiation	IEA	biological process
GO:0016557	peroxisome membrane biogenesis	IEA	biological process
GO:0005778	peroxisomal membrane	IEA	cellular component
GO:0005778	peroxisomal membrane	IEA	cellular component
GO:0044375	regulation of peroxisome size	IDA	biological process
GO:0032991	protein-containing complex	IDA	cellular component
GO:0042803	protein homodimerization activity	IDA	molecular function
GO:0016559	peroxisome fission	IDA	biological process
GO:0005779	integral component of peroxisomal membrane	IDA	cellular component
GO:0005779	integral component of peroxisomal membrane	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0005777	peroxisome	IDA	cellular component
GO:0007165	signal transduction	IMP	biological process
GO:0007031	peroxisome organization	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

KEGG pathways

Pathway id	Pathway name
hsa04146	Peroxisome

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881