Gene id |
8800 |
Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
Gene Symbol |
PEX11A Gene UCSC Ensembl |
Aliases |
PEX11-ALPHA, PMP28, hsPEX11p |
Gene name |
peroxisomal biogenesis factor 11 alpha |
Alternate names |
peroxisomal membrane protein 11A, 28 kDa peroxisomal integral membrane protein, peroxin-11A, peroxisomal biogenesis factor 11A, protein PEX11 homolog alpha, |
Gene location |
15q26.1 (89690753: 89681534) Exons: 3 NC_000015.10
|
Gene summary(Entrez) |
This gene is a member of the PEX11 family, which is composed of membrane elongation factors involved in regulation of peroxisome maintenance and proliferation. This gene product interacts with peroxisomal membrane protein 19 and may respond to outside sti
|
OMIM |
612985 |
Protein Summary
|
Protein general information
| O75192
Name: Peroxisomal membrane protein 11A (HsPEX11p) (28 kDa peroxisomal integral membrane protein) (PMP28) (Peroxin 11A) (Peroxisomal biogenesis factor 11A) (Protein PEX11 homolog alpha) (PEX11 alpha)
Length: 247 Mass: 28353
|
Sequence |
MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSI HATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVT CDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLG GLVSSIAGMITVAYPQMKLKTR
|
Structural information |
|
Other Databases |
GeneCards: PEX11A Malacards: PEX11A |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0005778 |
peroxisomal membrane
|
IBA |
cellular component |
GO:0016559 |
peroxisome fission
|
IBA |
biological process |
GO:0044375 |
regulation of peroxisome size
|
IBA |
biological process |
GO:0016559 |
peroxisome fission
|
IEA |
biological process |
GO:0005779 |
integral component of per oxisomal membrane
|
IEA |
cellular component |
GO:0007031 |
peroxisome organization
|
IEA |
biological process |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0005777 |
peroxisome
|
IEA |
cellular component |
GO:0016021 |
integral component of mem brane
|
IEA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005778 |
peroxisomal membrane
|
TAS |
cellular component |
GO:0019216 |
regulation of lipid metab olic process
|
TAS |
biological process |
GO:0050873 |
brown fat cell differenti ation
|
IEA |
biological process |
GO:0016557 |
peroxisome membrane bioge nesis
|
IEA |
biological process |
GO:0005778 |
peroxisomal membrane
|
IEA |
cellular component |
GO:0005778 |
peroxisomal membrane
|
IEA |
cellular component |
GO:0044375 |
regulation of peroxisome size
|
IDA |
biological process |
GO:0032991 |
protein-containing comple x
|
IDA |
cellular component |
GO:0042803 |
protein homodimerization activity
|
IDA |
molecular function |
GO:0016559 |
peroxisome fission
|
IDA |
biological process |
GO:0005779 |
integral component of per oxisomal membrane
|
IDA |
cellular component |
GO:0005779 |
integral component of per oxisomal membrane
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0007165 |
signal transduction
|
IMP |
biological process |
GO:0007031 |
peroxisome organization
|
IMP |
biological process |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005778 |
peroxisomal membrane
|
IBA |
cellular component |
GO:0016559 |
peroxisome fission
|
IBA |
biological process |
GO:0044375 |
regulation of peroxisome size
|
IBA |
biological process |
GO:0016559 |
peroxisome fission
|
IEA |
biological process |
GO:0005779 |
integral component of per oxisomal membrane
|
IEA |
cellular component |
GO:0007031 |
peroxisome organization
|
IEA |
biological process |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0005777 |
peroxisome
|
IEA |
cellular component |
GO:0016021 |
integral component of mem brane
|
IEA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005778 |
peroxisomal membrane
|
TAS |
cellular component |
GO:0019216 |
regulation of lipid metab olic process
|
TAS |
biological process |
GO:0050873 |
brown fat cell differenti ation
|
IEA |
biological process |
GO:0016557 |
peroxisome membrane bioge nesis
|
IEA |
biological process |
GO:0005778 |
peroxisomal membrane
|
IEA |
cellular component |
GO:0005778 |
peroxisomal membrane
|
IEA |
cellular component |
GO:0044375 |
regulation of peroxisome size
|
IDA |
biological process |
GO:0032991 |
protein-containing comple x
|
IDA |
cellular component |
GO:0042803 |
protein homodimerization activity
|
IDA |
molecular function |
GO:0016559 |
peroxisome fission
|
IDA |
biological process |
GO:0005779 |
integral component of per oxisomal membrane
|
IDA |
cellular component |
GO:0005779 |
integral component of per oxisomal membrane
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0005777 |
peroxisome
|
IDA |
cellular component |
GO:0007165 |
signal transduction
|
IMP |
biological process |
GO:0007031 |
peroxisome organization
|
IMP |
biological process |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005515 |
protein binding
|
IPI |
molecular function |
|
|
Pathway id | Pathway name |
hsa04146 | Peroxisome | |
|
Associated diseases |
References |
Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
21674046 |
Aberrant C pGs in Low Motility Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|