|
Gene id |
8672 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
EIF4G3 Gene UCSC Ensembl |
|
Aliases |
eIF-4G 3, eIF4G 3, eIF4GII |
|
Gene name |
eukaryotic translation initiation factor 4 gamma 3 |
|
Alternate names |
eukaryotic translation initiation factor 4 gamma 3, eIF-4-gamma 3, eIF-4-gamma II, |
|
Gene location |
1p36.12 (21176896: 20806291) Exons: 42 NC_000001.11
|
|
Gene summary(Entrez) |
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthes
|
|
OMIM |
603929 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
|
|
|
| Associated diseases |
References |
| Spermatogenesis defects | MIK: 29161344 |
| Male infertility and meiotic arrest of mouse spermatocytes | MIK: 20430745 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility and meiotic arrest of mouse spermatocytes | MIK: 20430745 |
| Spermatogenesis defects | MIK: 29161344 |
| Male infertility | MIK: 29161344 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 20430745 |
Male infer
tility and
meiotic a
rrest of m
ouse sperm
atocytes
|
|
|
|
Male infertility |
|
Show abstract |
| 29161344 |
Spermatoge
nesis, Mal
e infertil
ity
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|