|
Gene id |
8556 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
CDC14A Gene UCSC Ensembl |
|
Aliases |
DFNB105, DFNB32, DFNB35, cdc14, hCDC14 |
|
Gene name |
cell division cycle 14A |
|
Alternate names |
dual specificity protein phosphatase CDC14A, CDC10 (cell division cycle 10, S. cerevisiae, homolog), CDC14 cell division cycle 14 homolog A, deafness, autosomal recessive 32, |
|
Gene location |
1p21.2 (100345000: 100520280) Exons: 24 NC_000005.10
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA rep
|
|
OMIM |
603504 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa04110 | Cell cycle | |
|
| Associated diseases |
References |
| Deafness | OMIM: 603504 |
| Male infertility | MIK: 29293958 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29293958 |
Male infer
tility
|
p.C278S |
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|