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Gene id |
8505 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
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|
Gene Symbol |
PARG Gene UCSC Ensembl |
|
Aliases |
PARG99 |
|
Gene name |
poly(ADP-ribose) glycohydrolase |
|
Alternate names |
poly(ADP-ribose) glycohydrolase, mitochondrial poly(ADP-ribose) glycohydrolase, poly(ADP-ribose) glycohydrolase 60 kDa isoform, |
|
Gene location |
10q11.23 (49942026: 49818273) Exons: 21 NC_000010.11
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|
Gene summary(Entrez) |
Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smalle
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Protein Summary
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|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|