• Gene id: 85019

Gene Summary

• Gene Symbol: TMEM241   Gene   UCSC   Ensembl
• Aliases: C18orf45, hVVT
• Gene name: transmembrane protein 241
• Alternate names: transmembrane protein 241, putative vertebrate vrg4-like nucleotide-sugar transporter truncated variant2, putative vertebrate vrg4-like nucleotide-sugar transporter variant1, transmembrane protein C18orf45,
• Gene location: 18q11.2 (23437968: 23237251)     Exons: 23     NC_000018.10
• OMIM: 615430

Protein Summary

• Protein general information: Q24JQ0  
  • Name: Transmembrane protein 241
  • Length: 296  
  • Mass: 32647
• Sequence:

  MCVRRSLVGLTFCTCYLASYLTNKYVLSVLKFTYPTLFQGWQTLIGGLLLHVSWKLGWVEINSSSRSHVLVWLPA
  SVLFVGIIYAGSRALSRLAIPVFLTLHNVAEVIICGYQKCFQKEKTSPAKICSALLLLAAAGCLPFNDSQFNPDG
  YFWAIIHLLCVGAYKILQKSQKPSALSDIDQQYLNYIFSVVLLAFASHPTGDLFSVLDFPFLYFYRFHGSCCASG
  FLGFFLMFSTVKLKNLLAPGQCAAWIFFAKIITAGLSILLFDAILTSATTGCLLLGALGEALLVFSERKSS

• Structural information:
  • STRING: ENSP00000372720
• Other Databases: GeneCards:  TMEM241  Malacards:  TMEM241

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005338	nucleotide-sugar transmembrane transporter activity	IBA	molecular function
GO:0005457	GDP-fucose transmembrane transporter activity	IBA	molecular function
GO:0005794	Golgi apparatus	IBA	cellular component
GO:0015297	antiporter activity	IBA	molecular function
GO:0022857	transmembrane transporter activity	IBA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0055085	transmembrane transport	IEA	biological process
GO:0055085	transmembrane transport	IEA	biological process
GO:1901264	carbohydrate derivative transport	IEA	biological process
GO:0015931	nucleobase-containing compound transport	IEA	biological process
GO:0015783	GDP-fucose transmembrane transport	IEA	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq