• Gene id: 84985

Gene Summary

• Gene Symbol: FAM83A   Gene   UCSC   Ensembl
• Aliases: BJ-TSA-9
• Gene name: family with sequence similarity 83 member A
• Alternate names: protein FAM83A, tumor antigen BJ-TSA-9, tumor-specific gene expressed in prostate protein,
• Gene location: 8q24.13 (123179046: 123210078)     Exons: 7     NC_000008.11
• OMIM: 617791

Protein Summary

• Protein general information: Q86UY5  
  • Name: Protein FAM83A (Tumor antigen BJ TSA 9) (Tumor specific gene expressed in prostate protein)
  • Length: 434  
  • Mass: 47458
• Sequence:

  MSRSRHLGKIRKRLEDVKSQWVRPARADFSDNESARLATDALLDGGSEAYWRVLSQEGEVDFLSSVEAQYIQAQA
  REPPCPPDTLGGAEAGPKGLDSSSLQSGTYFPVASEGSEPALLHSWASAEKPYLKEKSSATVYFQTVKHNNIRDL
  VRRCITRTSQVLVILMDVFTDVEIFCDILEAANKRGVFVCVLLDQGGVKLFQEMCDKVQISDSHLKNISIRSVEG
  EIYCAKSGRKFAGQIREKFIISDWRFVLSGSYSFTWLCGHVHRNILSKFTGQAVELFDEEFRHLYASSKPVMGLK
  SPRLVAPVPPGAAPANGRLSSSSGSASDRTSSNPFSGRSAGSHPGTRSVSASSGPCSPAAPHPPPPPRFQPHQGP
  WGAPSPQAHLSPRPHDGPPAAVYSNLGAYRPTRLQLEQLGLVPRLTPTWRPFLQASPHF

• Structural information:
  • Interpro: IPR012461  
  • PDB: 4URJ
  • PDBsum: 4URJ
  • STRING: ENSP00000428876
• Other Databases: GeneCards:  FAM83A  Malacards:  FAM83A

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007165	signal transduction	IBA	biological process
GO:0019901	protein kinase binding	IBA	molecular function
GO:0007173	epidermal growth factor receptor signaling pathway	IBA	biological process
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	IDA	molecular function
GO:0019901	protein kinase binding	IDA	molecular function
GO:0007173	epidermal growth factor receptor signaling pathway	IDA	biological process
GO:0019901	protein kinase binding	IPI	molecular function
GO:0019901	protein kinase binding	IPI	molecular function
GO:0008283	cell population proliferation	IMP	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0042802	identical protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray