• Gene id: 84940

Gene Summary

• Gene Symbol: CORO6   Gene   UCSC   Ensembl
• Gene name: coronin 6
• Alternate names: coronin-6, clipin-E, coronin, actin binding protein 6, coronin-like protein E,
• Gene location: 17q11.2 (29622911: 29614235)     Exons: 13     NC_000017.11

Protein Summary

• Protein general information: Q6QEF8  
  • Name: Coronin 6 (Coronin like protein E) (Clipin E)
  • Length: 472  
  • Mass: 52762
• Sequence:

  MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYP
  LVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSA
  GGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRA
  VFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEP
  PFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEA
  DEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERV
  QAQEQRITALENMLCELVDGTD

• Structural information:
  • Interpro: IPR024977  IPR027337  IPR015505  IPR015048  IPR015943   IPR001680  IPR019775  IPR017986  IPR036322  
  • Prosite: PS00678 PS50082 PS50294
  • STRING: ENSP00000344562
• Other Databases: GeneCards:  CORO6  Malacards:  CORO6

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007015	actin filament organization	IBA	biological process
GO:0016477	cell migration	IBA	biological process
GO:0051015	actin filament binding	IBA	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R