|
Gene id |
84678 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
KDM2B Gene UCSC Ensembl |
|
Aliases |
CXXC2, FBXL10, Fbl10, JHDM1B, PCCX2 |
|
Gene name |
lysine demethylase 2B |
|
Alternate names |
lysine-specific demethylase 2B, CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JEMMA (Jumonji domain, EMSY-interactor, methyltransferase motif) protein, [Histone-H3]-lysine-36 demethy, |
|
Gene location |
12q24.31 (121582267: 121402287) Exons: 29 NC_000012.12
|
|
Gene summary(Entrez) |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), w
|
|
OMIM |
609078 |
|
| Associated diseases |
References |
| Spermatogenesis defects | MIK: 26984996 |
| Male factor infertility | MIK: 26984996 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility | MIK: 26984996 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 26984996 |
Role in sp
ermatogene
sis, Male
infertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|