• Gene id: 84553

Gene Summary

• Gene Symbol: FAXC   Gene   UCSC   Ensembl
• Aliases: C6orf168, dJ273F20
• Gene name: failed axon connections homolog, metaxin like GST domain containing
• Alternate names: failed axon connections homolog,
• Gene location: 6q16.2 (99350055: 99271160)     Exons: 9     NC_000006.12
• OMIM: 604043

Protein Summary

• Protein general information: Q5TGI0  
  • Name: Failed axon connections homolog
  • Length: 409  
  • Mass: 46843
• Sequence:

  MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSDPWWKKTLYLTGGALL
  AAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWI
  EYNHEKVSGTEFIIDFLEEKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGP
  FSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAM
  WTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTETFEDEGA
  ENSFSRTPDTDFTGHSLFDSDVDMDDYTDHEQCK

• Structural information:
  • Interpro: IPR026928  IPR036282  IPR033468  IPR012336  IPR036249  
  • STRING: ENSP00000374328
• Other Databases: GeneCards:  FAXC  Malacards:  FAXC

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray