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Gene id 8455
Gene Summary    Protein Summary    Gene ontology    Diseases    PubMed    

Gene Summary

Gene Symbol ATRN   Gene   UCSC   Ensembl
Aliases DPPT-L, MGCA
Gene name attractin
Alternate names attractin, attractin-2, mahogany homolog, mahogany protein,
Gene location 20p13 (3471017: 3651117)     Exons: 31     NC_000004.12
Gene summary(Entrez) This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune ce
OMIM 603130

Protein Summary

Gene ontology

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GO accessionTerm nameEvidence codeGo category
Associated diseases References
Cancer (squamous cell) GAD: 19384953
Melanoma GAD: 19320733
Male factor infertility MIK: 25318887
Obstructive azoospermia MIK: 25318887
Associated with testis vacuolation and impaired sperm function MIK: 20037821
Aberrant CpGs in Low Motility Sperm MIK: 21674046
Spermatogenic defects MIK: 20037821
Cryptorchidism MIK: 28606200
Obstructive azoospermia MIK: 25318887
Male infertility MIK: 25318887

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
20037821 Associated
with test
is vacuola
tion and i
mpaired sp
erm functi
on, which
may be res
ponsible f
or the imp
airment of
male repr
oductive a
bility


Male infertility
Show abstract
25318887 Obstructiv
e azoosper
mia, Male
infertilit
y


Male infertility
Show abstract
21674046 Aberrant C
pGs in Low
Motility
Sperm

18
Male infertility GSE26881
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract