• Gene id: 84337

Gene Summary

• Gene Symbol: ELOF1   Gene   UCSC   Ensembl
• Aliases: ELF1
• Gene name: elongation factor 1 homolog
• Alternate names: transcription elongation factor 1 homolog, ELF1 homolog, elongation factor 1, elongation factor 1 homolog (ELF1, S. cerevisiae),
• Gene location: 19p13.2 (11559235: 11553042)     Exons: 9     NC_000019.10
• OMIM: 0

Protein Summary

• Protein general information: P60002  
  • Name: Transcription elongation factor 1 homolog
  • Length: 83  
  • Mass: 9462
• Sequence:

  MGRRKSKRKPPPKKKMTGTLETQFTCPFCNHEKSCDVKMDRARNTGVISCTVCLEEFQTPITYLSEPVDVYSDWI
  DACEAANQ

• Structural information:
  • Interpro: IPR007808  IPR038567  
  • STRING: ENSP00000252445
• Other Databases: GeneCards:  ELOF1  Malacards:  ELOF1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0048096	chromatin-mediated maintenance of transcription	IBA	biological process
GO:0008023	transcription elongation factor complex	IBA	cellular component
GO:0006368	transcription elongation from RNA polymerase II promoter	IBA	biological process
GO:0000993	RNA polymerase II complex binding	IBA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq