• Gene id: 84331

Gene Summary

• Gene Symbol: MCRIP2   Gene   UCSC   Ensembl
• Aliases: C16orf14, FAM195A, c349E10.1
• Gene name: MAPK regulated corepressor interacting protein 2
• Alternate names: MAPK regulated corepressor interacting protein 2, MAPK regulated co-repressor interacting protein 2, family with sequence similarity 195, member A, protein FAM195A,
• Gene location: 16p13.3 (641827: 648473)     Exons: 8     NC_000016.10

Protein Summary

• Protein general information: Q9BUT9  
  • Name: MAPK regulated corepressor interacting protein 2 (Protein FAM195A)
  • Length: 160  
  • Mass: 17828
• Sequence:

  MYTITKGPSKLVAQRRTGPTQQQVEGRLGELLKCRQPAPPTSQPPRAQPFAQPPGPWPLSSPGPRLVFNRVNGRR
  APSTSPSFEGTQETYTVAHEENVRFVSEAWQQVQQQLDGGPAGEGGPRPVQYVERTPNPRLQNFVPIDLDEWWAQ
  QFLARITSCS

• Structural information:
  • Interpro: IPR029428  
  • STRING: ENSP00000305138
• Other Databases: GeneCards:  MCRIP2  Malacards:  MCRIP2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0010494	cytoplasmic stress granule	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0005634	nucleus	IDA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0010494	cytoplasmic stress granule	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq