• Gene id: 84248

Gene Summary

• Gene Symbol: FYTTD1   Gene   UCSC   Ensembl
• Aliases: UIF
• Gene name: forty-two-three domain containing 1
• Alternate names: UAP56-interacting factor, forty-two-three domain-containing protein 1, protein 40-2-3,
• Gene location: 3q29 (197749552: 197787595)     Exons: 12     NC_000003.12
• OMIM: 616933

Protein Summary

• Protein general information: Q96QD9  
  • Name: UAP56 interacting factor (Forty two three domain containing protein 1) (Protein 40 2 3)
  • Length: 318  
  • Mass: 35818
  • Tissue specificity: Expressed in a wide variety of cancer types. {ECO
• Sequence:

  MNRFGTRLVGATATSSPPPKARSNENLDKIDMSLDDIIKLNRKEGKKQNFPRLNRRLLQQSGAQQFRMRVRWGIQ
  QNSGFGKTSLNRRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDKNIEQYFPVLKRKANLLRQNEGQ
  RKPVAVLKRPSQLSRKNNIPANFTRSGNKLNHQKDTRQATFLFRRGLKVQAQLNTEQLLDDVVAKRTRQWRTSTT
  NGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKE
  QRATLTYNKGGSRFVTVG

• Structural information:
  • Interpro: IPR009782  
  • DIP: 62119
  • STRING: ENSP00000241502
• Other Databases: GeneCards:  FYTTD1  Malacards:  FYTTD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003723	RNA binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0016607	nuclear speck	IEA	cellular component
GO:0005654	nucleoplasm	IEA	cellular component
GO:0016607	nuclear speck	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0003729	mRNA binding	IBA	molecular function
GO:0016607	nuclear speck	IBA	cellular component
GO:0006406	mRNA export from nucleus	IBA	biological process
GO:0005654	nucleoplasm	IDA	cellular component
GO:0003729	mRNA binding	IDA	molecular function
GO:0016607	nuclear speck	IDA	cellular component
GO:0006406	mRNA export from nucleus	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0003729	mRNA binding	IEA	molecular function
GO:0006406	mRNA export from nucleus	IEA	biological process
GO:0051028	mRNA transport	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq