Gene id |
83871 |
Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
Gene Symbol |
RAB34 Gene UCSC Ensembl |
Aliases |
NARR, RAB39, RAH |
Gene name |
RAB34, member RAS oncogene family |
Alternate names |
ras-related protein Rab-34, nine amino-acid residue-repeats, ras-related protein Rab-39, ras-related protein Rah, |
Gene location |
17q11.2 (28718439: 28714280) Exons: 11 NC_000017.11
|
Gene summary(Entrez) |
This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the acti
|
Protein Summary
|
Protein general information
| P0DI83
Name: Ras related protein Rab 34, isoform NARR (Nine amino acid residue repeats)
Length: 198 Mass: 21118
|
Sequence |
MVGQPQPRDDVGSPRPRVIVGTIRPRVIVGTIRPRVIVGSARARPPPDGTPRPQLAAEESPRPRVIFGTPRARVI LGSPRPRVIVSSPWPAVVVASPRPRTPVGSPWPRVVVGTPRPRVIVGSPRARVADADPASAPSQGALQGRRQDEH SGTRAEGSRPGGAAPVPEEGGRFARAQRLPPPRHLRLPGAPDRHRGQI
|
Structural information |
|
Other Databases |
GeneCards: RAB34  Malacards: RAB34 |
Protein general information
| Q9BZG1
Name: Ras related protein Rab 34 (Ras related protein Rab 39) (Ras related protein Rah)
Length: 259 Mass: 29044
|
Sequence |
MNILAPVRRDRVLAELPQCLRKEAALHGHKDFHPRVTCACQEHRTGTVGFKISKVIVVGDLSVGKTCLINRFCKD TFDKNYKATIGVDFEMERFEVLGIPFSLQLWDTAGQERFKCIASTYYRGAQAIIIVFNLNDVASLEHTKQWLADA LKENDPSSVLLFLVGSKKDLSTPAQYALMEKDALQVAQEMKAEYWAVSSLTGENVREFFFRVAALTFEANVLAEL EKSGARRIGDVVRINSDDSNLYLTASKKKPTCCP
|
Structural information |
|
Other Databases |
GeneCards: RAB34  Malacards: RAB34 |
|
GO accession | Term name | Evidence code | Go category |
---|
GO:0030742 |
GTP-dependent protein bin ding
|
IPI |
molecular function |
GO:0032482 |
Rab protein signal transd uction
|
IBA |
biological process |
GO:0012505 |
endomembrane system
|
IBA |
cellular component |
GO:0003924 |
GTPase activity
|
IBA |
molecular function |
GO:0090385 |
phagosome-lysosome fusion
|
IBA |
biological process |
GO:0006897 |
endocytosis
|
IBA |
biological process |
GO:0006886 |
intracellular protein tra nsport
|
IBA |
biological process |
GO:0045335 |
phagocytic vesicle
|
IDA |
cellular component |
GO:0090382 |
phagosome maturation
|
IMP |
biological process |
GO:0045880 |
positive regulation of sm oothened signaling pathwa y
|
ISS |
biological process |
GO:0090385 |
phagosome-lysosome fusion
|
IMP |
biological process |
GO:0003924 |
GTPase activity
|
IEA |
molecular function |
GO:0005525 |
GTP binding
|
IEA |
molecular function |
GO:0031410 |
cytoplasmic vesicle
|
IEA |
cellular component |
GO:0042995 |
cell projection
|
IEA |
cellular component |
GO:0005794 |
Golgi apparatus
|
IEA |
cellular component |
GO:0030030 |
cell projection organizat ion
|
IEA |
biological process |
GO:0005525 |
GTP binding
|
IEA |
molecular function |
GO:0016020 |
membrane
|
IEA |
cellular component |
GO:0000166 |
nucleotide binding
|
IEA |
molecular function |
GO:0015031 |
protein transport
|
IEA |
biological process |
GO:0005737 |
cytoplasm
|
IEA |
cellular component |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0005737 |
cytoplasm
|
IEA |
cellular component |
GO:0045335 |
phagocytic vesicle
|
IEA |
cellular component |
GO:0005929 |
cilium
|
IEA |
cellular component |
GO:0030670 |
phagocytic vesicle membra ne
|
IEA |
cellular component |
GO:0005794 |
Golgi apparatus
|
IEA |
cellular component |
GO:0072659 |
protein localization to p lasma membrane
|
IDA |
biological process |
GO:0005795 |
Golgi stack
|
IDA |
cellular component |
GO:0048471 |
perinuclear region of cyt oplasm
|
IDA |
cellular component |
GO:0032587 |
ruffle membrane
|
IDA |
NOT|cellular component |
GO:0032418 |
lysosome localization
|
IDA |
biological process |
GO:0005794 |
Golgi apparatus
|
IDA |
cellular component |
GO:0044351 |
macropinocytosis
|
IDA |
NOT|biological process |
GO:0043001 |
Golgi to plasma membrane protein transport
|
IDA |
biological process |
GO:0031985 |
Golgi cisterna
|
IDA |
cellular component |
GO:0031982 |
vesicle
|
IDA |
cellular component |
GO:0005515 |
protein binding
|
IPI |
molecular function |
GO:0070062 |
extracellular exosome
|
HDA |
cellular component |
GO:0019882 |
antigen processing and pr esentation
|
IMP |
biological process |
GO:0017160 |
Ral GTPase binding
|
IPI |
molecular function |
|
|
Associated diseases |
References |
Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
Hypospermatogenesis | MIK: 28361989 |
Spermatogenic defects | MIK: 31037746 |
|
|
PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
21674046 |
Aberrant C pGs in Low Motility Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
28361989 |
Hyposperma togenesis
|
|
|
6 (3 controls, 3 Klienfelter s yndrome
|
Male infertility |
Microarray
|
Show abstract |
31037746 |
Spermatoge nic defect s
|
|
|
28 men with az oospermia
|
Male infertility |
Microarray
|
Show abstract |
|