• Gene id: 83606

Gene Summary

• Gene Symbol: GUCD1   Gene   UCSC   Ensembl
• Aliases: C22orf13, LLN4
• Gene name: guanylyl cyclase domain containing 1
• Alternate names: protein GUCD1, CG13760 gene product [Drosophila melanogaster] homolog, guanylyl cyclase domain-containing protein 1,
• Gene location: 22q11.23 (24555934: 24540422)     Exons: 7     NC_000022.11
• OMIM: 0

Protein Summary

• Protein general information: Q96NT3  
  • Name: Protein GUCD1 (Guanylyl cyclase domain containing protein 1) (Protein LLN4)
  • Length: 240  
  • Mass: 27207
• Sequence:

  MRTEAEAAGPPLEPGDFVQLPVPVIQQLYHWDCGLACSRMVLRYLGQLDDSEFERALQKLQLTRSIWTIDLAYLM
  HHFGVRHRFCTQTLGVDKGYKNQSFYRKHFDTEETRVNQLFAQAKACKVLVEKCTVSVKDIQAHLAQGHVAIVLV
  NSGVLHCDLCSSPVKYCCFTPSGHHCFCRTPDYQGHFIVLRGYNRATGCIFYNNPAYADPGMCSTSISNFEEART
  SYGTDEDILFVYLDS

• Structural information:
  • Interpro: IPR018616  
  • STRING: ENSP00000479370
• Other Databases: GeneCards:  GUCD1  Malacards:  GUCD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq