|
Gene id |
8290 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
H3-4 Gene UCSC Ensembl |
|
Aliases |
H3.4, H3/g, H3FT, H3t, HIST3H3 |
|
Gene name |
H3.4 histone |
|
Alternate names |
histone H3.1t, H3 histone family, member T, H3/t, histone 3, H3, histone cluster 3 H3, |
|
Gene location |
1q42.13 (228425359: 228424844) Exons: 1 NC_000001.11
|
|
Gene summary(Entrez) |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core hi
|
|
OMIM |
602820 |
Protein Summary
|
|
| Pathway id | Pathway name |
|---|
| hsa05202 | Transcriptional misregulation in cancer | | hsa05322 | Systemic lupus erythematosus | | hsa05034 | Alcoholism | |
|
| Associated diseases |
References |
| Endometriosis | INFBASE: 25820690 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Spermatogenic defects | MIK: 28099840 |
| Male infertility | MIK: 28099840 |
| Non obstructive azoospermia | MIK: 23869807 |
| Sertoli cell only syndrome | MIK: 23869807 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 28099840 |
Essential
for entry
into sperm
atogenesis
, Male inf
ertility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 23869807 |
Non obstru
ctive azoo
spermia, S
ertoli cel
l only syn
drome
|
|
|
20 (4 controls,
16 cases)
|
Male infertility |
GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|