• Gene id: 81932

Gene Summary

• Gene Symbol: HDHD3   Gene   UCSC   Ensembl
• Aliases: 2810435D12Rik, C9orf158
• Gene name: haloacid dehalogenase like hydrolase domain containing 3
• Alternate names: haloacid dehalogenase-like hydrolase domain-containing protein 3,
• Gene location: 9q32 (113376985: 113373415)     Exons: 3     NC_000009.12

Protein Summary

• Protein general information: Q9BSH5  
  • Name: Haloacid dehalogenase like hydrolase domain containing protein 3
  • Length: 251  
  • Mass: 28000
• Sequence:

  MAHRLQIRLLTWDVKDTLLRLRHPLGEAYATKARAHGLEVEPSALEQGFRQAYRAQSHSFPNYGLSHGLTSRQWW
  LDVVLQTFHLAGVQDAQAVAPIAEQLYKDFSHPCTWQVLDGAEDTLRECRTRGLRLAVISNFDRRLEGILGGLGL
  REHFDFVLTSEAAGWPKPDPRIFQEALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVRDSV
  PKEHILPSLAHLLPALDCLEGSTPGL

• Structural information:
  • Interpro: IPR036412  IPR006439  IPR011949  IPR041492  IPR023214  
  • PDB: 3K1Z
  • PDBsum: 3K1Z
  • STRING: ENSP00000238379
• Other Databases: GeneCards:  HDHD3  Malacards:  HDHD3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016787	hydrolase activity	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0043231	intracellular membrane-bounded organelle	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)