• Gene id: 81605

Gene Summary

• Gene Symbol: URM1   Gene   UCSC   Ensembl
• Aliases: C9orf74
• Gene name: ubiquitin related modifier 1
• Alternate names: ubiquitin-related modifier 1, ubiquitin-related modifier 1 homolog,
• Gene location: 9q34.11 (128371318: 128392015)     Exons: 3     NC_000009.12
• OMIM: 605554

Protein Summary

• Protein general information: Q9BTM9  
  • Name: Ubiquitin related modifier 1
  • Length: 101  
  • Mass: 11380
• Sequence:

  MAAPLSVEVEFGGGAELLFDGIKKHRVTLPGQEEPWDIRNLLIWIKKNLLKERPELFIQGDSVRPGILVLINDAD
  WELLGELDYQLQDQDSVLFISTLHGG

• Structural information:
  • Interpro: IPR012675  IPR016155  IPR015221  
  • CDD: cd01764
  • DIP: 48631
  • STRING: ENSP00000412922
• Other Databases: GeneCards:  URM1  Malacards:  URM1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0031386	protein tag	IBA	molecular function
GO:0032447	protein urmylation	IBA	biological process
GO:0002143	tRNA wobble position uridine thiolation	IBA	biological process
GO:0005634	nucleus	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0097163	sulfur carrier activity	IBA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0034227	tRNA thio-modification	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0008033	tRNA processing	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0006400	tRNA modification	TAS	biological process
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0032447	protein urmylation	IEA	biological process
GO:0005829	cytosol	IEA	cellular component
GO:0034227	tRNA thio-modification	IEA	biological process
GO:0002098	tRNA wobble uridine modification	IEA	biological process
GO:0005829	cytosol	IC	cellular component
GO:0097163	sulfur carrier activity	IDA	molecular function
GO:0002098	tRNA wobble uridine modification	IMP	biological process
GO:0034227	tRNA thio-modification	IMP	biological process
GO:0031386	protein tag	IBA	molecular function
GO:0032447	protein urmylation	IBA	biological process
GO:0002143	tRNA wobble position uridine thiolation	IBA	biological process
GO:0005634	nucleus	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0097163	sulfur carrier activity	IBA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0034227	tRNA thio-modification	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0008033	tRNA processing	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0006400	tRNA modification	TAS	biological process
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0032447	protein urmylation	IEA	biological process
GO:0005829	cytosol	IEA	cellular component
GO:0034227	tRNA thio-modification	IEA	biological process
GO:0002098	tRNA wobble uridine modification	IEA	biological process
GO:0005829	cytosol	IC	cellular component
GO:0097163	sulfur carrier activity	IDA	molecular function
GO:0002098	tRNA wobble uridine modification	IMP	biological process
GO:0034227	tRNA thio-modification	IMP	biological process

KEGG pathways

Pathway id	Pathway name
hsa04122	Sulfur relay system

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq