• Gene id: 81572

Gene Summary

• Gene Symbol: PDRG1   Gene   UCSC   Ensembl
• Aliases: C20orf126, PDRG
• Gene name: p53 and DNA damage regulated 1
• Alternate names: p53 and DNA damage-regulated protein 1, epididymis secretory sperm binding protein,
• Gene location: 20q11.21 (41955225: 42087829)     Exons: 27     NC_000018.10
• OMIM: 610789

Protein Summary

• Protein general information: Q9NUG6  
  • Name: p53 and DNA damage regulated protein 1
  • Length: 133  
  • Mass: 15511
  • Tissue specificity: Predominantly expressed in normal testis and exhibits reduced but detectable expression in other organs. {ECO
• Sequence:

  MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKE
  MIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG

• Structural information:
  • Interpro: IPR030482  IPR002777  
  • DIP: 27568
  • STRING: ENSP00000202017
• Other Databases: GeneCards:  PDRG1  Malacards:  PDRG1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0006457	protein folding	IEA	biological process
GO:0051082	unfolded protein binding	IEA	molecular function
GO:0016272	prefoldin complex	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881