|
Gene id |
81565 |
| Gene Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
NDEL1 Gene UCSC Ensembl |
|
Aliases |
EOPA, MITAP1, NDE1L1, NDE2, NUDEL |
|
Gene name |
nudE neurodevelopment protein 1 like 1 |
|
Alternate names |
nuclear distribution protein nudE-like 1, endooligopeptidase A, mitosin-associated protein 1, mitosin-associated protein MITAP1, nudE nuclear distribution E homolog-like 1, nudE nuclear distribution gene E homolog-like 1, protein Nudel, |
|
Gene location |
17p13.1 (8435883: 8472743) Exons: 13 NC_000003.12
|
|
Gene summary(Entrez) |
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have
|
|
OMIM |
607538 |
|
| Associated diseases |
References |
| Schizophrenia | GAD: 19632097 |
| Plays an important role in germ cell formation, including nucleoplasmic transport and nucleus shaping by manchette microtubules | MIK: 15147871 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Spermatogenic defects | MIK: 15147871 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 15147871 |
Plays an i
mportant r
ole in ger
m cell for
mation, in
cluding nu
cleoplasmi
c transpor
t and nucl
eus shapin
g by manch
ette micro
tubules
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|