• Gene id: 81563

Gene Summary

• Gene Symbol: C1orf21   Gene   UCSC   Ensembl
• Aliases: PIG13
• Gene name: chromosome 1 open reading frame 21
• Alternate names: uncharacterized protein C1orf21, cell proliferation-inducing gene 13 protein, proliferation-inducing protein 13,
• Gene location: 1q25.3 (184387028: 184629018)     Exons: 6     NC_000001.11
• OMIM: 147586

Protein Summary

• Protein general information: Q9H246  
  • Name: Uncharacterized protein C1orf21 (Cell proliferation inducing gene 13 protein)
  • Length: 121  
  • Mass: 13865
  • Tissue specificity: Expressed in spleen, prostate, testis and uterus. {ECO
• Sequence:

  MGCASAKHVATVQNEEEAQKGKNYQNGDVFGDEYRIKPVEEVKYMKNGAEEEQKIAARNQENLEKSASSNVRLKT
  NKEVPGLVHQPRANMHISESQQEFFRMLDEKIEKGRDYCSEEEDIT

• Structural information:
  • Interpro: IPR027967  
  • STRING: ENSP00000235307
• Other Databases: GeneCards:  C1orf21  Malacards:  C1orf21

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R