• Gene id: 80851

Gene Summary

• Gene Symbol: SH3BP5L   Gene   UCSC   Ensembl
• Gene name: SH3 binding domain protein 5 like
• Alternate names: SH3 domain-binding protein 5-like, SH3BP-5-like,
• Gene location: 1q44 (248825914: 248810445)     Exons: 11     NC_000001.11

Protein Summary

• Protein general information: Q7L8J4  
  • Name: SH3 domain binding protein 5 like (SH3BP 5 like)
  • Length: 393  
  • Mass: 43499
• Sequence:

  MAELRQVPGGRETPQGELRPEVVEDEVPRSPVAEEPGGGGSSSSEAKLSPREEEELDPRIQEELEHLNQASEEIN
  QVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREM
  VFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPY
  FELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSSPVGAEAGPED
  MEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDHVSLDGQELGTRSGGR
  RGSDGGARGGRHQRSVSL

• Structural information:
  • Interpro: IPR007940  
  • STRING: ENSP00000355428
• Other Databases: GeneCards:  SH3BP5L  Malacards:  SH3BP5L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0035556	intracellular signal transduction	IEA	biological process
GO:0061099	negative regulation of protein tyrosine kinase activity	IBA	biological process
GO:0035556	intracellular signal transduction	IBA	biological process
GO:0005737	cytoplasm	IBA	cellular component
GO:0004860	protein kinase inhibitor activity	IBA	molecular function
GO:0005085	guanyl-nucleotide exchange factor activity	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0017112	Rab guanyl-nucleotide exchange factor activity	IDA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq