• Gene id: 805

Gene Summary

• Gene Symbol: CALM2   Gene   UCSC   Ensembl
• Aliases: CALM, CALML2, CAM1, CAM3, CAMC, CAMII, CAMIII, LQT15, PHKD, PHKD2, caM
• Gene name: calmodulin 2
• Alternate names: calmodulin-2, Calmodulin-1, Calmodulin-3, LP7057 protein, calmodulin 2 (phosphorylase kinase, delta), phosphorylase kinase delta, phosphorylase kinase subunit delta, prepro-calmodulin 2,
• Gene location: 2p21 (47176935: 47160081)     Exons: 8     NC_000002.12
• Gene summary(Entrez): This gene is a member of the calmodulin gene family. There are three distinct calmodulin genes dispersed throughout the genome that encode the identical protein, but differ at the nucleotide level. Calmodulin is a calcium binding protein that plays a role
• OMIM: 114182

Protein Summary

Gene ontology

GO accession	Term name	Evidence code	Go category

KEGG pathways

Pathway id	Pathway name
hsa05200	Pathways in cancer
hsa05010	Alzheimer disease
hsa05012	Parkinson disease
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04024	cAMP signaling pathway
hsa05163	Human cytomegalovirus infection
hsa04020	Calcium signaling pathway
hsa05034	Alcoholism
hsa05170	Human immunodeficiency virus 1 infection
hsa04022	cGMP-PKG signaling pathway
hsa05167	Kaposi sarcoma-associated herpesvirus infection
hsa04261	Adrenergic signaling in cardiomyocytes
hsa05152	Tuberculosis
hsa04740	Olfactory transduction
hsa04921	Oxytocin signaling pathway
hsa04371	Apelin signaling pathway
hsa04910	Insulin signaling pathway
hsa04218	Cellular senescence
hsa04728	Dopaminergic synapse
hsa04270	Vascular smooth muscle contraction
hsa05418	Fluid shear stress and atherosclerosis
hsa04114	Oocyte meiosis
hsa04722	Neurotrophin signaling pathway
hsa04070	Phosphatidylinositol signaling system
hsa04915	Estrogen signaling pathway
hsa04922	Glucagon signaling pathway
hsa04916	Melanogenesis
hsa04713	Circadian entrainment
hsa04625	C-type lectin receptor signaling pathway
hsa04925	Aldosterone synthesis and secretion
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04970	Salivary secretion
hsa04912	GnRH signaling pathway
hsa04971	Gastric acid secretion
hsa04720	Long-term potentiation
hsa05031	Amphetamine addiction
hsa04924	Renin secretion
hsa05214	Glioma
hsa05133	Pertussis
hsa04744	Phototransduction

Diseases

Associated diseases	References
Long QT syndrome	KEGG:H00720
Long QT syndrome	KEGG:H00720
Major depressive disorder	PMID:22885997
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881