• Gene id: 8045

Gene Summary

• Gene Symbol: RASSF7   Gene   UCSC   Ensembl
• Aliases: C11orf13, CFAP88, FAP88, HRAS1, HRC1
• Gene name: Ras association domain family member 7
• Alternate names: ras association domain-containing protein 7, HRAS1-related cluster protein 1, HRAS1-related cluster-1, Ras association (RalGDS/AF-6) domain family (N-terminal) member 7, Ras association (RalGDS/AF-6) domain family 7,
• Gene location: 11p15.5 (560969: 564024)     Exons: 6     NC_000011.10
• OMIM: 143023

Protein Summary

• Protein general information: Q02833  
  • Name: Ras association domain containing protein 7 (HRAS1 related cluster protein 1)
  • Length: 373  
  • Mass: 39945
• Sequence:

  MLLGLAAMELKVWVDGIQRVVCGVSEQTTCQEVVIALAQAIGQTGRFVLVQRLREKERQLLPQECPVGAQATCGQ
  FASDVQFVLRRTGPSLAGRPSSDSCPPPERCLIRASLPVKPRAALGCEPRKTLTPEPAPSLSRPGPAAPVTPTPG
  CCTDLRGLELRVQRNAEELGHEAFWEQELRREQAREREGQARLQALSAATAEHAARLQALDAQARALEAELQLAA
  EAPGPPSPMASATERLHQDLAVQERQSAEVQGSLALVSRALEAAERALQAQAQELEELNRELRQCNLQQFIQQTG
  AALPPPPRPDRGPPGTQGPLPPAREESLLGAPSESHAGAQPRPRGGPHDAELLEVAAAPAPEWCPLAAQPQAL

• Structural information:
  • Protein Domains: (6..8-)
    (/note="Ras-associating-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00166"-)
  • Interpro: IPR033593  IPR000159  IPR033631  IPR029071  
  • Prosite: PS50200
  • STRING: ENSP00000380713
• Other Databases: GeneCards:  RASSF7  Malacards:  RASSF7

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007165	signal transduction	IEA	biological process
GO:0070507	regulation of microtubule cytoskeleton organization	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0006915	apoptotic process	IEA	biological process
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005815	microtubule organizing center	IEA	cellular component
GO:0034451	centriolar satellite	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq