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Gene id 80313
Gene Summary    Protein Summary    Diseases    PubMed    

Gene Summary

Gene Symbol LRRC27   Gene   UCSC   Ensembl
Gene name leucine rich repeat containing 27
Alternate names leucine-rich repeat-containing protein 27, testicular tissue protein Li 108,
Gene location 10q26.3 (132330062: 132381507)     Exons: 20     NC_000010.11
OMIM 0

Protein Summary

Protein general information Q9C0I9  

Name: Leucine rich repeat containing protein 27

Length: 530  Mass: 60089

Sequence MEGSSSYEVPSVAAADLEEGAGQTRSLPATPSKDVHKGVGGIIFSSSPILDLSESGLCRLEEVFRIPSLQQLHLQ
RNALCVIPQDFFQLLPNLTWLDLRYNRIKALPSGIGAHQHLKTLLLERNPIKMLPVELGSVTTLKALNLRHCPLE
FPPQLVVQKGLVAIQRFLRMWAVEHSLPRNPTSQEAPPVREMTLRDLPSPGLELSGDHASNQGAVNAQDPEGAVM
KEKASFLPPVEKPDLSELRKSADSSENWPSEEEIRRFWKLRQEIVEHVKADVLGDQLLTRELPPNLKAALNIEKE
LPKPRHVFRRKTASSRSILPDLLSPYQMAIRAKRLEESRAAALRELQEKQALMEQQRREKRALQEWRERAQRMRK
RKEELSKLLPPRRSMVASKIPSATDLIDNRKVPLNPPGKMKPSKEKSPQASKEMSALQERNLEEKIKQHVLQMRE
QRRFHGQAPLEEMRKAAEDLEIATELQDEVLKLKLGLTLNKDRRRAALTGNLSLGLPAAQPQNTFFNTKYGESGN
VRRYQ
Structural information
Interpro:  IPR001611  IPR003591  IPR032675  
Prosite:   PS51450
STRING:   ENSP00000357603
Other Databases GeneCards:  LRRC27  Malacards:  LRRC27
Associated diseases References
Cryptorchidism MIK: 28606200
Spermatogenic defects MIK: 31037746
Teratozoospermia MIK: 17327269

PubMed references

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PMID Condition Mutation Ethnicity Population details Infertility_type Associated_genes Abstract
17327269 Teratozoos
permia

19 (6 controls
, 13 cases)
Male infertility GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
Show abstract
28606200 Cryptorchi
dism

Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
Male infertility MeDIP-Seq
Show abstract
31037746 Spermatoge
nic defect
s

28 men with az
oospermia
Male infertility Microarray
Show abstract