• Gene id: 80063

Gene Summary

• Gene Symbol: ATF7IP2   Gene   UCSC   Ensembl
• Aliases: MCAF2
• Gene name: activating transcription factor 7 interacting protein 2
• Alternate names: activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin associated factor 2,
• Gene location: 16p13.2-p13.13 (10386060: 10483642)     Exons: 17     NC_000016.10
• OMIM: 613645

Protein Summary

• Protein general information: Q5U623  
  • Name: Activating transcription factor 7 interacting protein 2 (ATF7 interacting protein 2) (MBD1 containing chromatin associated factor 2)
  • Length: 682  
  • Mass: 75764
• Sequence:

  MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGAS
  SLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTN
  VTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSG
  FVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTS
  EQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAKIAKLQRRI
  KTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSE
  SNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLES
  HSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITK
  INPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKSIP
  GFSENLT

• Structural information:
  • Protein Domains: (575..68-)
    (/note="Fibronectin-type-III)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00316"-)
  • Interpro: IPR026085  IPR026089  IPR031870  IPR003961  
  • Prosite: PS50853
  • STRING: ENSP00000379808
• Other Databases: GeneCards:  ATF7IP2  Malacards:  ATF7IP2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881