|
Gene id |
79923 |
| Gene Summary KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
NANOG Gene UCSC Ensembl |
|
Gene name |
Nanog homeobox |
|
Alternate names |
homeobox protein NANOG, homeobox transcription factor Nanog, homeobox transcription factor Nanog-delta 48, |
|
Gene location |
12p13.31 (7789401: 7799145) Exons: 4 NC_000012.12
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own expressio
|
|
OMIM |
607937 |
|
| Pathway id | Pathway name |
|---|
| hsa04550 | Signaling pathways regulating pluripotency of stem cells | | hsa05205 | Proteoglycans in cancer | |
|
| Associated diseases |
References |
| Plays a role in meiotic and post-meiotic stages of male germ cell development | MIK: 20539761 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 20539761 |
Plays a ro
le in meio
tic and po
st-meiotic
stages of
male germ
cell deve
lopment
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
|